LOCUS       DAVKMO010000001       109025 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVKMO010000001 DAVKMO010000000
VERSION     DAVKMO010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 109025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 109025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..109025
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.001"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            86..484
                     /gene="spx"
                     /locus_tag="VW361_000001"
     CDS             86..484
                     /gene="spx"
                     /locus_tag="VW361_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU9743156.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            550..1119
                     /locus_tag="VW361_000002"
     CDS             550..1119
                     /locus_tag="VW361_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU9743157.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSNYISDRLANGATEQ"
     gene            1206..1472
                     /locus_tag="VW361_000003"
     CDS             1206..1472
                     /locus_tag="VW361_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU9743158.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            1476..1895
                     /gene="ruvX"
                     /locus_tag="VW361_000004"
     CDS             1476..1895
                     /gene="ruvX"
                     /locus_tag="VW361_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU9743159.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            1911..2216
                     /locus_tag="VW361_000005"
     CDS             1911..2216
                     /locus_tag="VW361_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU9743160.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            2523..3773
                     /locus_tag="VW361_000006"
     CDS             2523..3773
                     /locus_tag="VW361_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9743161.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSYREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            3770..4288
                     /locus_tag="VW361_000007"
     CDS             3770..4288
                     /locus_tag="VW361_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU9743162.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDGTYTGQDDG
                     DRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNGNQIVVDDM
                     DRDPSDQIVLTK"
     gene            4434..5966
                     /gene="cls"
                     /locus_tag="VW361_000008"
     CDS             4434..5966
                     /gene="cls"
                     /locus_tag="VW361_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU9743163.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGINLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            6224..7762
                     /locus_tag="VW361_000009"
     CDS             6224..7762
                     /locus_tag="VW361_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU9743164.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLQVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVEVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            7882..10089
                     /gene="nrdD"
                     /locus_tag="VW361_000010"
     CDS             7882..10089
                     /gene="nrdD"
                     /locus_tag="VW361_000010"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU9743165.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            10101..10241
                     /locus_tag="VW361_000011"
     CDS             10101..10241
                     /locus_tag="VW361_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743166.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            10285..10791
                     /locus_tag="VW361_000012"
     CDS             10285..10791
                     /locus_tag="VW361_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9743167.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDTENFVYEEWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDAHNGVER
                     YWIEVANE"
     gene            10784..11374
                     /gene="nrdG"
                     /locus_tag="VW361_000013"
     CDS             10784..11374
                     /gene="nrdG"
                     /locus_tag="VW361_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU9743168.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGILYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            11371..11988
                     /locus_tag="VW361_000014"
     CDS             11371..11988
                     /locus_tag="VW361_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU9743169.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            12254..12562
                     /gene="rpsJ"
                     /locus_tag="VW361_000015"
     CDS             12254..12562
                     /gene="rpsJ"
                     /locus_tag="VW361_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU9743170.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            12779..13405
                     /gene="rplC"
                     /locus_tag="VW361_000016"
     CDS             12779..13405
                     /gene="rplC"
                     /locus_tag="VW361_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU9743171.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            13430..14053
                     /gene="rplD"
                     /locus_tag="VW361_000017"
     CDS             13430..14053
                     /gene="rplD"
                     /locus_tag="VW361_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU9743172.1"
                     /translation="MANVTLFDQTGKEAGQVVLNDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            14053..14349
                     /locus_tag="VW361_000018"
     CDS             14053..14349
                     /locus_tag="VW361_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU9743173.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            14367..15200
                     /gene="rplB"
                     /locus_tag="VW361_000019"
     CDS             14367..15200
                     /gene="rplB"
                     /locus_tag="VW361_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU9743174.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            15304..15585
                     /gene="rpsS"
                     /locus_tag="VW361_000020"
     CDS             15304..15585
                     /gene="rpsS"
                     /locus_tag="VW361_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU9743175.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            15597..15941
                     /gene="rplV"
                     /locus_tag="VW361_000021"
     CDS             15597..15941
                     /gene="rplV"
                     /locus_tag="VW361_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU9743176.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            15954..16607
                     /gene="rpsC"
                     /locus_tag="VW361_000022"
     CDS             15954..16607
                     /gene="rpsC"
                     /locus_tag="VW361_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU9743177.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            16611..17024
                     /gene="rplP"
                     /locus_tag="VW361_000023"
     CDS             16611..17024
                     /gene="rplP"
                     /locus_tag="VW361_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU9743178.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            17034..17240
                     /locus_tag="VW361_000024"
     CDS             17034..17240
                     /locus_tag="VW361_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU9743179.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            17265..17525
                     /gene="rpsQ"
                     /locus_tag="VW361_000025"
     CDS             17265..17525
                     /gene="rpsQ"
                     /locus_tag="VW361_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU9743180.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            17551..17919
                     /gene="rplN"
                     /locus_tag="VW361_000026"
     CDS             17551..17919
                     /gene="rplN"
                     /locus_tag="VW361_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU9743181.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            17997..18302
                     /gene="rplX"
                     /locus_tag="VW361_000027"
     CDS             17997..18302
                     /gene="rplX"
                     /locus_tag="VW361_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU9743182.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            18326..18868
                     /gene="rplE"
                     /locus_tag="VW361_000028"
     CDS             18326..18868
                     /gene="rplE"
                     /locus_tag="VW361_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU9743183.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            18886..19155
                     /gene="rpsN"
                     /locus_tag="VW361_000029"
     CDS             18886..19155
                     /gene="rpsN"
                     /locus_tag="VW361_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU9743184.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            19440..19838
                     /gene="rpsH"
                     /locus_tag="VW361_000030"
     CDS             19440..19838
                     /gene="rpsH"
                     /locus_tag="VW361_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU9743185.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            20030..20566
                     /gene="rplF"
                     /locus_tag="VW361_000031"
     CDS             20030..20566
                     /gene="rplF"
                     /locus_tag="VW361_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU9743186.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            20650..21006
                     /gene="rplR"
                     /locus_tag="VW361_000032"
     CDS             20650..21006
                     /gene="rplR"
                     /locus_tag="VW361_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU9743187.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            21024..21518
                     /gene="rpsE"
                     /locus_tag="VW361_000033"
     CDS             21024..21518
                     /gene="rpsE"
                     /locus_tag="VW361_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU9743188.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            21490..21714
                     /gene="rpmD"
                     /locus_tag="VW361_000034"
     CDS             21490..21714
                     /gene="rpmD"
                     /locus_tag="VW361_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU9743189.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            21859..22299
                     /gene="rplO"
                     /locus_tag="VW361_000035"
     CDS             21859..22299
                     /gene="rplO"
                     /locus_tag="VW361_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU9743190.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            22312..23622
                     /gene="secY"
                     /locus_tag="VW361_000036"
     CDS             22312..23622
                     /gene="secY"
                     /locus_tag="VW361_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU9743191.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            23773..24411
                     /locus_tag="VW361_000037"
     CDS             23773..24411
                     /locus_tag="VW361_000037"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU9743192.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            24528..24746
                     /gene="infA"
                     /locus_tag="VW361_000038"
     CDS             24528..24746
                     /gene="infA"
                     /locus_tag="VW361_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU9743193.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            24771..24887
                     /gene="rpmJ"
                     /locus_tag="VW361_000039"
     CDS             24771..24887
                     /gene="rpmJ"
                     /locus_tag="VW361_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU9743194.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            24905..25270
                     /gene="rpsM"
                     /locus_tag="VW361_000040"
     CDS             24905..25270
                     /gene="rpsM"
                     /locus_tag="VW361_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU9743195.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            25288..25671
                     /gene="rpsK"
                     /locus_tag="VW361_000041"
     CDS             25288..25671
                     /gene="rpsK"
                     /locus_tag="VW361_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU9743196.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            25714..26649
                     /locus_tag="VW361_000042"
     CDS             25714..26649
                     /locus_tag="VW361_000042"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU9743197.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            26661..27047
                     /gene="rplQ"
                     /locus_tag="VW361_000043"
     CDS             26661..27047
                     /gene="rplQ"
                     /locus_tag="VW361_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU9743198.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            27312..27578
                     /locus_tag="VW361_000044"
     CDS             27312..27578
                     /locus_tag="VW361_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU9743199.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            27588..28925
                     /locus_tag="VW361_000045"
     CDS             27588..28925
                     /locus_tag="VW361_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU9743200.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            29169..29861
                     /locus_tag="VW361_000046"
     CDS             29169..29861
                     /locus_tag="VW361_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9743201.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLISGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(29964..31609)
                     /locus_tag="VW361_000047"
                     /pseudo
     CDS             complement(29964..31609)
                     /locus_tag="VW361_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(31599..32690)
                     /locus_tag="VW361_000048"
     CDS             complement(31599..32690)
                     /locus_tag="VW361_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743202.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLGLMQIAQYADRKPDKLSGGQQQRVTLACVLAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     KELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDGYALRMLALDQVEEQAIHV
                     SIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASKIQVSEESTFEEELQKGNR
                     IRLRINTQKLNIFSADGSQNLIKGVNHGT"
     gene            complement(32703..33824)
                     /locus_tag="VW361_000049"
                     /pseudo
     CDS             complement(32703..33824)
                     /locus_tag="VW361_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(34041..34238)
                     /locus_tag="VW361_000050"
     CDS             complement(34041..34238)
                     /locus_tag="VW361_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9743203.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKHLHISPKELKLLGRIVK"
     gene            complement(34313..35089)
                     /locus_tag="VW361_000051"
     CDS             complement(34313..35089)
                     /locus_tag="VW361_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU9743204.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            35211..35957
                     /locus_tag="VW361_000052"
     CDS             35211..35957
                     /locus_tag="VW361_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9743205.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYETKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRVIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     CQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAVSDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            35970..36950
                     /locus_tag="VW361_000053"
     CDS             35970..36950
                     /locus_tag="VW361_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU9743206.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNVGIVKIEIENFDTNMFKLENYVKEKYSLESLEIIPNEFDDTPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            37145..37465
                     /locus_tag="VW361_000054"
     CDS             37145..37465
                     /locus_tag="VW361_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9743207.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            37511..37819
                     /locus_tag="VW361_000055"
     CDS             37511..37819
                     /locus_tag="VW361_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9743208.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            37836..39134
                     /locus_tag="VW361_000056"
     CDS             37836..39134
                     /locus_tag="VW361_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9743209.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            39264..41702
                     /locus_tag="VW361_000057"
     CDS             39264..41702
                     /locus_tag="VW361_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU9743210.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            41721..42389
                     /locus_tag="VW361_000058"
     CDS             41721..42389
                     /locus_tag="VW361_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU9743211.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            42407..43495
                     /locus_tag="VW361_000059"
     CDS             42407..43495
                     /locus_tag="VW361_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU9743212.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            43950..46451
                     /locus_tag="VW361_000060"
     CDS             43950..46451
                     /locus_tag="VW361_000060"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU9743213.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDISREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            46669..46881
                     /locus_tag="VW361_000061"
     CDS             46669..46881
                     /locus_tag="VW361_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU9743214.1"
                     /translation="MIGESMEGYTPGELTSIELLEGRYARIEALSVEKHAEDLLAVYG
                     PDTPQEMWTYLFQEPVADMEELVSLL"
     gene            46981..47437
                     /locus_tag="VW361_000062"
                     /pseudo
     CDS             46981..47437
                     /locus_tag="VW361_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            47449..47865
                     /locus_tag="VW361_000063"
     CDS             47449..47865
                     /locus_tag="VW361_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9743215.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEQTERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(48492..48584)
                     /locus_tag="VW361_000064"
     CDS             complement(48492..48584)
                     /locus_tag="VW361_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU9743216.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            48745..49716
                     /gene="ruvB"
                     /locus_tag="VW361_000065"
     CDS             48745..49716
                     /gene="ruvB"
                     /locus_tag="VW361_000065"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU9743217.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            49697..50269
                     /locus_tag="VW361_000066"
                     /pseudo
     CDS             49697..50269
                     /locus_tag="VW361_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
     gene            50500..51258
                     /locus_tag="VW361_000067"
     CDS             50500..51258
                     /locus_tag="VW361_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU9743218.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            51267..52070
                     /locus_tag="VW361_000068"
     CDS             51267..52070
                     /locus_tag="VW361_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU9743219.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFVLTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            52092..53351
                     /gene="rseP"
                     /locus_tag="VW361_000069"
     CDS             52092..53351
                     /gene="rseP"
                     /locus_tag="VW361_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU9743220.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            53364..55217
                     /locus_tag="VW361_000070"
     CDS             53364..55217
                     /locus_tag="VW361_000070"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU9743221.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            55316..56695
                     /gene="bglA"
                     /locus_tag="VW361_000071"
     CDS             55316..56695
                     /gene="bglA"
                     /locus_tag="VW361_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU9743222.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNTQGVDFYRK
                     VFEAIKAKGICLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDT
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPDSPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            56887..58695
                     /gene="glmS"
                     /locus_tag="VW361_000072"
     CDS             56887..58695
                     /gene="glmS"
                     /locus_tag="VW361_000072"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU9743223.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGTDNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVVDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLIHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            58814..59863
                     /locus_tag="VW361_000073"
     CDS             58814..59863
                     /locus_tag="VW361_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU9743224.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(59963..63760)
                     /gene="spuA"
                     /locus_tag="VW361_000074"
     CDS             complement(59963..63760)
                     /gene="spuA"
                     /locus_tag="VW361_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU9743225.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATSKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSNDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQNEASHPAHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVRKESVENSSKENISATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            64177..64590
                     /gene="rpsL"
                     /locus_tag="VW361_000075"
     CDS             64177..64590
                     /gene="rpsL"
                     /locus_tag="VW361_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU9743226.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            64610..65080
                     /gene="rpsG"
                     /locus_tag="VW361_000076"
     CDS             64610..65080
                     /gene="rpsG"
                     /locus_tag="VW361_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU9743227.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            65505..67586
                     /gene="fusA"
                     /locus_tag="VW361_000077"
     CDS             65505..67586
                     /gene="fusA"
                     /locus_tag="VW361_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU9743228.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            67690..72081
                     /locus_tag="VW361_000078"
     CDS             67690..72081
                     /locus_tag="VW361_000078"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU9743229.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQTTEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            72183..72446
                     /locus_tag="VW361_000079"
     CDS             72183..72446
                     /locus_tag="VW361_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU9743230.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            72439..72717
                     /locus_tag="VW361_000080"
     CDS             72439..72717
                     /locus_tag="VW361_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU9743231.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVCECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            72738..72890
                     /locus_tag="VW361_000081"
     CDS             72738..72890
                     /locus_tag="VW361_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743232.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            72912..74153
                     /locus_tag="VW361_000082"
     CDS             72912..74153
                     /locus_tag="VW361_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU9743233.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NATSDEEAVDLLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVLLFRNGNWAN"
     gene            74163..74393
                     /locus_tag="VW361_000083"
     CDS             74163..74393
                     /locus_tag="VW361_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9743234.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            74616..75338
                     /locus_tag="VW361_000084"
     CDS             74616..75338
                     /locus_tag="VW361_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9743235.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            75556..76890
                     /gene="pepC"
                     /locus_tag="VW361_000085"
     CDS             75556..76890
                     /gene="pepC"
                     /locus_tag="VW361_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU9743236.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAETIVLTPWDPMGALAE"
     gene            complement(76946..77857)
                     /locus_tag="VW361_000086"
     CDS             complement(76946..77857)
                     /locus_tag="VW361_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9743237.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(77881..78684)
                     /locus_tag="VW361_000087"
     CDS             complement(77881..78684)
                     /locus_tag="VW361_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU9743238.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(78712..79701)
                     /gene="manX"
                     /locus_tag="VW361_000088"
     CDS             complement(78712..79701)
                     /gene="manX"
                     /locus_tag="VW361_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU9743239.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVVANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQAAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIDISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(79934..80953)
                     /gene="adhP"
                     /locus_tag="VW361_000089"
     CDS             complement(79934..80953)
                     /gene="adhP"
                     /locus_tag="VW361_000089"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU9743240.1"
                     /translation="MKAVVVKPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVARLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(81292..82104)
                     /locus_tag="VW361_000090"
     CDS             complement(81292..82104)
                     /locus_tag="VW361_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9743241.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKNPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            82294..83712
                     /locus_tag="VW361_000091"
     CDS             82294..83712
                     /locus_tag="VW361_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU9743242.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            83766..84473
                     /locus_tag="VW361_000092"
     CDS             83766..84473
                     /locus_tag="VW361_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9743243.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQMSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     SWGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            84567..85541
                     /gene="folP"
                     /locus_tag="VW361_000093"
     CDS             84567..85541
                     /gene="folP"
                     /locus_tag="VW361_000093"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU9743244.1"
                     /translation="MMKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLITEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFNQTFTVEELADFETLPIEDLMVAFFERALARAAEAGIAPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            85543..86865
                     /locus_tag="VW361_000094"
     CDS             85543..86865
                     /locus_tag="VW361_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9743245.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLFDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEGKDAPR
                     LAYGTDYQVRHQDSVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNVTDKKEEKQTVRIVTGSLYFLSQVRVYLMERKNENGYTKD"
     gene            86846..87400
                     /gene="folE"
                     /locus_tag="VW361_000095"
     CDS             86846..87400
                     /gene="folE"
                     /locus_tag="VW361_000095"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU9743246.1"
                     /translation="MDTQKIEAAVKMIIEAVGEDANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVIIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            87443..88255
                     /gene="folK"
                     /locus_tag="VW361_000096"
     CDS             87443..88255
                     /gene="folK"
                     /locus_tag="VW361_000096"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU9743247.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(88300..88617)
                     /locus_tag="VW361_000097"
     CDS             complement(88300..88617)
                     /locus_tag="VW361_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU9743248.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            88972..89418
                     /gene="rplM"
                     /locus_tag="VW361_000098"
     CDS             88972..89418
                     /gene="rplM"
                     /locus_tag="VW361_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU9743249.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            89437..89829
                     /gene="rpsI"
                     /locus_tag="VW361_000099"
     CDS             89437..89829
                     /gene="rpsI"
                     /locus_tag="VW361_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU9743250.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            90220..90558
                     /locus_tag="VW361_000100"
     CDS             90220..90558
                     /locus_tag="VW361_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU9743251.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQEALDKHHQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            90748..92184
                     /locus_tag="VW361_000101"
     CDS             90748..92184
                     /locus_tag="VW361_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU9743252.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSLAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAVHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTAQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            92236..92475
                     /locus_tag="VW361_000102"
     CDS             92236..92475
                     /locus_tag="VW361_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HEU9743253.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGTIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            92605..92919
                     /locus_tag="VW361_000103"
     CDS             92605..92919
                     /locus_tag="VW361_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU9743254.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            93037..95016
                     /locus_tag="VW361_000104"
     CDS             93037..95016
                     /locus_tag="VW361_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU9743255.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKFGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMVQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEEKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            95026..95340
                     /locus_tag="VW361_000105"
     CDS             95026..95340
                     /locus_tag="VW361_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU9743256.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            95371..95877
                     /locus_tag="VW361_000106"
     CDS             95371..95877
                     /locus_tag="VW361_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743257.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATIEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKVYQQFVQ
                     LEKNSLSL"
     gene            95957..97303
                     /gene="celB"
                     /locus_tag="VW361_000107"
     CDS             95957..97303
                     /gene="celB"
                     /locus_tag="VW361_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU9743258.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANSATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            97684..97860
                     /locus_tag="VW361_000108"
     CDS             97684..97860
                     /locus_tag="VW361_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743259.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFRSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            98261..100474
                     /locus_tag="VW361_000109"
     CDS             98261..100474
                     /locus_tag="VW361_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU9743260.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDSLWLLNHYHYQDSCKNAEGGLTLSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVQTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDVSNI
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(100696..101172)
                     /locus_tag="VW361_000110"
     CDS             complement(100696..101172)
                     /locus_tag="VW361_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU9743261.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDHKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            101395..104598
                     /locus_tag="VW361_000111"
                     /pseudo
     CDS             101395..104598
                     /locus_tag="VW361_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            104979..105355
                     /gene="tnpA"
                     /locus_tag="VW361_000112"
                     /pseudo
     CDS             104979..105355
                     /gene="tnpA"
                     /locus_tag="VW361_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(105743..106372)
                     /locus_tag="VW361_000113"
     CDS             complement(105743..106372)
                     /locus_tag="VW361_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU9743262.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDKSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPSSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYVTLR"
     gene            complement(106382..107383)
                     /locus_tag="VW361_000114"
     CDS             complement(106382..107383)
                     /locus_tag="VW361_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU9743263.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIQPNMLDMDSLFQGISHFHFSGITVAIGQEVRTILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(107414..108055)
                     /locus_tag="VW361_000115"
     CDS             complement(107414..108055)
                     /locus_tag="VW361_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU9743264.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKGYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(108074..108889)
                     /locus_tag="VW361_000116"
     CDS             complement(108074..108889)
                     /locus_tag="VW361_000116"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU9743265.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
BASE COUNT        33167 a        19465 c        24152 g        32241 t
ORIGIN      
        1 aaattaaaaa taggtcgcaa gtcggatgtt ttttatggta taatagacta aactgatagt
       61 aacatgtagc gaaaggggta ggtacatgat taaaatttat acagtctcaa gttgtactag
      121 ctgtaaaaaa gcaaaaacct ggctcaatgc ccaccagtta agttataaag aacaaaacct
      181 tggtaaagaa ggaattacga gagaagaatt actggatatt ctaaccaaaa cagataacgg
      241 aatagccagc atcgtttcgt ctaaaaatcg ctatgccaaa gcccttggag tggatattga
      301 agatttgagt gtcaatgaag ttctcaatct gattatggaa acaccgagaa ttttaaagag
      361 cccaatcctt gtagatgaaa aacgcctgca agttggctac aaggaagacg atattcgtgc
      421 cttcctacca cgctctgtcc gtaatgtaga aaatgcagaa gcacgtttgc gtgcagctct
      481 ataaacatca aggctgggag cacttcccag tcttattcta ttttaatttc aaaaagaaag
      541 aagaaagaaa tgaaaaaaat agttcttgtt agtctagctt tcctttttgt cctggttggt
      601 tgcggacaga aaaaagaaac tggaccagct acaaaaacag aaaaagatac gcttcagtcg
      661 gcattgccag ttattgaaaa tgctgagaag aatacagttg taactaagac tttggtcttg
      721 cccaagtcag atgatggtag ccagcaaact caaaccatta catacaagga caagactttt
      781 ttgagcttaa cgattcaaca aaaacgtcca gtttctgatg agttgaagac ttatattgac
      841 caacatggag tggaagaaac tcaaaaagct cttcttgaag cggaggagaa ggataagtct
      901 atcattgaag ctcgtaaatt ggtaggtttc aaacttgaaa caaaactatt gagcgcaacg
      961 gaacttcaaa caacgactag ttttgatttt caagttctgg atgtcaagaa ggcttcccag
     1021 ttggaacatc tgaagaatat tggtttggaa aatcttttga aaaatgaacc aagcaactat
     1081 atttcagaca gattggcaaa tggtgcgaca gaacagtaga aaatccaaat aaatagactg
     1141 cctgaattgt agaaggtaag gaattatgct ataatggtac tattctaagg aaagagggtg
     1201 ttagaatggg atttactgaa gaaacagtac gttttaaatt ggacgattcc aataaaaaag
     1261 aaattagcga aactttgaca gatgtttatg cttcgttgaa cgataagggt tacaacccaa
     1321 ttaaccaaat cgtaggttac gtattgagtg gagaccctgc ctacgttcct cgttataata
     1381 atgcacgaaa tcaaatccgt aagtatgagc gtgatgaaat cgttgaggaa ttggttcgct
     1441 actacctcaa aggacaagga gtcgatctat aacctatgag aattatggga ttggacgtcg
     1501 gttcaaaaac ggtaggggtg gcgattagcg atccgcttgg ttttacagct caagggcttg
     1561 aaatcatcca gataaatgaa gaacaaggcc aatttggttt tgaccgcgtt aaggaattgg
     1621 ttgatactta caaggtggaa cgatttgtag tgggcttgcc taaaaacatg aacaatacaa
     1681 gtggaccgcg cgtagaagct agtcaagcct acggagcaaa gctagaagag ttttttggtt
     1741 taccagtaga ctatcaggat gaacgcttga caacagtggc tgctgagcgc atgttgattg
     1801 aacaagcaga tatcagtcgc aataagcgca agaaagtcat tgataagtta gcagctcagc
     1861 tgattttaca aaattattta gatagaaaat tttaatataa aggagaggct atgtcacacg
     1921 atcataacca cgaccacgaa gaacgtgaac taatcacact agtagatgag caaggaaatg
     1981 aaaccttgtt tgaaatcctt ttgacaattg atggaaaaga agaatttggt aaaaactatg
     2041 ttcttctagt accagttaac gcagaagaag acgaagacgg acaagttgaa atccaagctt
     2101 actcattcat cgaaaacgaa gatggaacag aaggcgaatt gcaaccaatc ccagaagact
     2161 cagaagacga atggaacatg attgaagaag tcttcaacag ctttatggag gagtaaaaac
     2221 gtccggggga cgtttttagc cctgcgctag aaattagaaa cgcaggtagt ctgagagact
     2281 gtatcagccc aactcccaga aatggggaag agttggaacg tccagtgaac atttttaccc
     2341 caactcctag aaattgagaa gagttggaac atctagtgga tatttttagc ccacgttcac
     2401 attcatagta gctagttatt agctaaccag gtaagaggtc gggacgaaaa tcctggcctt
     2461 gtttttatta gtaactatac tttaatgcga taattgattg gacttttgtc aaggagatgt
     2521 gtatgtttga agtagaagaa tggcttcata gtcggattgg tttgaatttt cgatcaggtt
     2581 tgggccgaat acagcaagcg gtggatttgt taggaaatcc tgagcagtct taccctatta
     2641 tccacgtaac agggactaat gggaaaggat ctaccattgc ttttatgagg gaattattta
     2701 tggggcatgg caaaaaagtt gcgaccttta cctcccctca tatcgtatcc atcaatgacc
     2761 gaatttgcat taatgggcaa cctatagcag acgcagactt tatccgtttg gctgatcagg
     2821 tcaaggagat ggagaaaacg cttctgcaaa ctcctgacca gttgtccttt tttgaattgc
     2881 tgaccttggt tgcttttctt tattttaggg agcaggaggt ggatttggtt ttattagaag
     2941 tgggaattgg tggcttactt gacacgacca atgtggtaac tggagagctt gctgtcatca
     3001 cctccattgg gcttgaccat caagaaacct tgggtgatag tctagaagca attgcagagc
     3061 agaaagctgg tattttcaag gctggtaaga aggcagtgat tgcgaaattg cctccagaag
     3121 ctaggcttgt ctgtcagaaa aaagccgaat ctttagctgt taacctttat caggcaggtc
     3181 aagatttttt aatgctgaat ggtgattttt caagctcttt actaaatctt tcacagctga
     3241 acataggctt agaaggagtc tatcagcagg agaatgcagc cttggcgttg caaacttttc
     3301 ttctttttat gggagaagga aaggaagctg ttgatgaaca ggctgtaaga aaggccttgg
     3361 aacagaccca ttgggctggt cgcttggagc gtattcgccc acagatttac ttggatggtg
     3421 ctcataacct ccctgccttg actcgcttgg ttgagtttat caaagaaaaa gagcaggaag
     3481 gttatcgtcc tcaaatcctt tttggagcct tgaaacggaa ggattatcaa gggatgttag
     3541 gttacctgac tgaaaaattg cctcaggtgg aactcaaggt gaccggcttt gactatcagg
     3601 gggctttgga cgaaagggat gtgacaggtt acgatatagt ttcttcttac cgagaattta
     3661 tcagcgattt tgaagaaaga gcagatgctc aggatttgct gttcgttaca gggtctctct
     3721 attttatctc agaagtacgg ggctacctgc tggaccgtga gcagataaat tgaccccctt
     3781 gtttgaactt gttatactag gggaattgct ggttagagaa aatttctcta aattggtagc
     3841 agaaaggaaa ttcatcatga aattaaaaag attcacactt tctcttgctt ctctagcaag
     3901 ttttagtctc ttagtagctt gttcacaaag agctcaacag gttcaacagc ctgctcaaca
     3961 gaataccaat actgcaaatg caggaggtaa ccaaaatcaa gcggctccag tacaaaacca
     4021 acctgttgct caaccgaccg atattgatgg gacttatact ggtcaggatg acggagaccg
     4081 tatcacttta gtggtaactg gaacgactgg tacatggact gagctcgaat ctgacgggga
     4141 tcagaaagtc aaacaggtta catttgattc agcaaatcaa cgcatgatta ttggcgatga
     4201 tgtcaaaatt tacactgtaa acggtaatca aatcgtcgta gatgatatgg atagagaccc
     4261 atcggaccaa atcgttttaa ctaaataaga ctatgcaagt agaaagggct ggatttttca
     4321 gcctttttac ttttacctag aaaataatca taaatacttg ccttctaccg aatacctgcg
     4381 ttatactagt atcaattact tgtttttagc attcaaacta tcaaggaggg gatatgaaat
     4441 ataggaaatt tcaattattg atgtccaagt atggctttag tctttcgatt atgctacttg
     4501 aactttgtct tgtttttggt ctctttcttt atttaggacg catggctccc attttatgga
     4561 ttactgtcct cattctactg agtatcatca caatcatttc gatagtcaac cgtaatacga
     4621 ctcctgagaa taaggtaacc tggttgttag tagcctttgt gccagtattt ggtcccttgc
     4681 tctatctgat gtttggtgaa aggcgattgt ccaaaaaaga aatcaaacaa ctgaagaagc
     4741 taggctctat gcatttccaa gaagcaaata gccagctact aaaagagaaa ttaaaagaaa
     4801 gtgacaaggc agcttatgga gtcatcaagt ccttattgag tatggatacc aatgctgaca
     4861 tctatgatca aactgcctct acattttttc ctaacggaga agctatgtgg aaaaagatgg
     4921 tagaagatct taaaaaggct gagaaattta ttttcttgga atattacatt atagaagaag
     4981 gtttgatgtg gaatcgcata ctagatatac tagagcaaaa ggtagctcag ggtgtagagg
     5041 ttaagatgct ctatgatgat atcggctgta tggctacttt aacaggagat tatgcacatc
     5101 gacttcgtca gctgggcatc gaggcccata aattcaataa agttattcct cgtttgacag
     5161 tggcttataa taacagagat catagaaaaa tattgattgt tgatggtcag atagcctata
     5221 ctggtgggat caatctggca gatgagtaca ttaaccacgt cgagagattt ggttattgga
     5281 aggatagtgg aattcgctta gacggactag cagtaaaagc tctgacacgc ttatttttga
     5341 ccacttggta cattaatcga ggagaaatta gtgattttga tcaatatcat ttagaaaatc
     5401 attctatccc gagtgacggt ttaaccattc catacggaag tggacccaag ccaatttttc
     5461 gagcgcaggt agggaaaaaa gtttatcaga gtttaatcaa tcaagcaaca gaatcggtct
     5521 atattacgac accttatttg attatagatt atgatttaac agagacaatc aaaaatgcag
     5581 ctatgagagg ggtcgatgtt cgaattatca ccccttacat accagataag aagttcattc
     5641 agttagtcac gagaggagct tatcccgacc ttctttctgc tggtgttcgg atttatgagt
     5701 atagtccagg ttttattcat agtaagcaga tgttggtaga cgaagatttt gcggtggtgg
     5761 ggacaatcaa tctcgactac cggagcttgg tacaccatta tgaaaatgca gtcttactct
     5821 ataaaactcc ttctataagg gaaatcgccc gagattttcg aaatatattt gcagattctc
     5881 aggaagtcta tcctcattct atcaaaacga gctggtatca aaagcttgta aaagaaatcg
     5941 cccagctatt cgcccctatc ttataagaaa tctagaactt aggatacaaa ccagacctat
     6001 ttttcttgtc ttttacgaat agaaagaaag aggaggggaa ttcatgctaa ctaaggaaga
     6061 agtgaatgat atgattgagt tcaaacagac acatttacac cgctttcggg aaattgaaac
     6121 ctttgtgaaa ctatgcaaaa aatcactcaa acagccatcg caagctgaca atcctaggac
     6181 tttttgatat actaagacag ataaattgaa caggagaaac gatatgagtg tgtatggtag
     6241 agtagaagaa gttcataagg agaatcgtga acctctagaa taccaaatcg aacaagaatc
     6301 gcatcatcgt gaatcaagtc gtcttccttt ggtgaaaatt ttactatgga gtacgcttgt
     6361 aacggggata actctaggag taccgctatt actcgactta atgagtgcac aagaagtgca
     6421 ggatttttat gcaggttggg cgcttcatca gacagggaag atttacagcg actattatgg
     6481 aagtcaaggt ttgctttatt atttgctgac ttacgtgagt cagggcggat ttttctttgc
     6541 catctttgag tggttagcct tggtagcagg aggatttttc ctttttagat cagcggacac
     6601 cttgacagag caaggagacc aagctggaca tctggtgact attttttaca tgctagttac
     6661 aggtcttgct tttggtggag gctatgcgac tcttttagcg cttcctttct tattcgcagc
     6721 ctttagttta gttgcggctt acctaagcaa tccaagccat gataagggat ttgtacggat
     6781 tgggctagct ttggcaggcg gatttttctt tgctccctta tcatcgctcc tgtttattgc
     6841 tgtagtgagt ttaggcttgt tggtctttaa ccttgggcat agacgctttg cgcatgggtt
     6901 ttatcagttt cttgcagtgg ctttaggttt ttcacttgtc ttttatccaa ctgcctacta
     6961 tagtgctgca acaggaagtt ttggggatgc gattagtggt attcgttatc ctattgacag
     7021 tattcgcttt gattttactt ctaaaatttt agagaatatg tttttttatg gcttgttgtc
     7081 ccttggtttg ggatttgtgg tttgtatctt tttaggtctc tttcaatcca aaccctttaa
     7141 actatacgtc atttcggttc ctgcaagtct tgtggtaatt ttaggtttga ttttactttt
     7201 cttttcacaa gagcctctgc acgcttctta tttgatggtc gtcttccctg ttttcctact
     7261 tttattggta accaatatta agagtcaaca gagggggcgt agtgctagaa gaagccgaag
     7321 agaaacgcca gttagcctat ggagtcgttt cttcaaagga aatctatatc tgcaagtttt
     7381 tgggtttgtc tatcttttgt ctgttccttt tttgatgaag tttgtccttt atccagtacc
     7441 ttatcaagaa cgtaatcgtc ttgctgattt ggtaaaagag gagacaaata cggaagatgc
     7501 tatctatgca tgggatgata ctgcgactct ttatcgtaag agtgagcgct tgtcgccatc
     7561 ggcgattttg tccccgttgc actatacagc aactgaggaa aatcgtaata agttacttaa
     7621 tgacttgaaa gaaaaacaac ctaaggtgat tgtggtaaat gacaaggtgg aagtctggtc
     7681 tgaagtggaa acactcttaa aagaaaatta ccaacaagta aagactgatt actcagagtt
     7741 taaagtctat aaaattaaat aaccaaatca atatcttgtg tatttttaaa aattttaaga
     7801 tttttaacac aagatattga tttttctttt tagagtggta taatactttt tagaaagaac
     7861 attttagaaa agagcatgca tatgattgca ctagaagaaa aaattacaat tttgccaact
     7921 ctcttcgtcg agaaacgaga tgggagacgt gttgtatttg atgtggacaa gattgacaag
     7981 gctctccaca aggcagctga caaggttatg gatgtgacac ccctggttga aaaacgcctc
     8041 aatgatctga ctgagagaat tattacagaa attcatagtc gctttccaca gggaattaag
     8101 atttacgaaa ttcaaaatat cgtagaacat gaactccttg aagccaaaga atatgcgctg
     8161 gctgaggagt atattactta tcggacacag agggattttg agcgctcaaa agcgacggat
     8221 atcaacttta gtattcataa acttctcaac aaagaccaga cagttgtcaa tgaaaatgct
     8281 aataaagaca gtgatgtctt taacactcag cgtgatttga cagcagggat tgttgggaaa
     8341 tcaatcggac tgcaaatgct tcctaagcac gtagccaatg cccaccaaaa gggggatatc
     8401 cactatcacg atttggacta cagtccctat acccctatga ccaactgctg tttgattgat
     8461 tttaagggta tgttggaaaa tggttttaag attggaaatg cagaggtaga gagtcccaag
     8521 tctatccaga ctgcgacagc acagatttct caaatcattg ccaacgttgc ttctagccag
     8581 tacggtggct gttcagctga ccgtatcgat gaaattttgg cgccttatgc agagaagaac
     8641 tatcaaaaac atctcaaaga tgcagaagag tgggtattgc ctgaaaaacg ggaagattac
     8701 gcttggaaga aaacgcaaaa ggacatttac gatgccatgc aatctcttga gtatgaaatc
     8761 aatactctct tcacttcaaa tggacaaaca ccttttactt cgctaggttt tggtctggga
     8821 accagtcgtt ttgaacgaga aattcaaaaa gctattttaa acattcgcat caagggtctt
     8881 ggttcagaac accgtacggc tatctttcct aaacttattt tcactctgaa aagaggcctt
     8941 aatttagagg aaggaactcc caactacgac atcaagcagt tggctcttga gtgtgcaacc
     9001 aaacggatgt atccagatgt tttatcttac gataagattg ttgacttgac aggatccttc
     9061 aaggtgccta tgggttgccg ttctttcctc caaggatgga aggatgaaaa tggtgtagaa
     9121 gtcaattcag gtcgcatgaa tctgggtgtt gtgacggtta atctgcctcg tattgctctt
     9181 gagtctgaag gtgatatgaa taagttctgg gaaatcttca acgagcgaat gaatatcgca
     9241 gaagatgctc ttgtttaccg tgtcgaacgc actaaagagg cgacaccagc gaatgctcct
     9301 atcctttatc agtacggtgc ttttggccat cgtctaggta aagaagaaag tgttgaccag
     9361 ctctttaaga atcgtcgtgc gaccgtttcg ctgggctata tcggcttgta tgaagtagcg
     9421 acagttttct ttggtaacag ctgggaaagt aatccagatg ctaaggaatt cacgctagac
     9481 atcattcacg atatgaaacg ccgtgtagaa gagtggtcag accaatatgg ctaccatttc
     9541 tctatctact caacaccatc cgaaagtctg acagaccgtt tctgccgact agatatagac
     9601 aagtttggct ctattcctga tatcacagac aaggaatact acaccaactc tttccactac
     9661 gatgttcgta aaaatccaac accgtttgaa aaattggact ttgagaaagt ctatccagaa
     9721 gcaggtgcgt caggtggttt catccattat tgtgagtatc cagtccttca gcaaaatcca
     9781 aaggccttgg aagctgtctg ggattatgct tatgaccgtg taggctatct aggcaccaat
     9841 actccgattg accgttgcta caagtgtgac tttgaagggg attttgaacc aactgagaga
     9901 gggtttgctt gtccaaactg tggcaatagc gaccctaaaa cagtagatgt ggtgaagcga
     9961 acttgtggct acctaggtaa tcctcaagca agaccgatgg tcaacgggcg tcacaaggaa
    10021 atcgctgcgc gtgtcaaaca tatgaatggt tcaacgatta aaatagctgg gcatcaagta
    10081 acaaattaga aagaaatgaa atgggaaaat atcaactaga cgataagggg cgcgcacaag
    10141 tgacccgtta tcacgagaaa cactctaaag gtggagctgg taagaaagaa cgcttgctta
    10201 gcttcagaga acaattttta aacaagaaca agaaaaaata aaagtgagag ccagctctcg
    10261 cttttctcat agtgggaggt aaggatggaa ttacgcagac caagattagc ggataagaaa
    10321 gctgttttag atatgatgac agagtttgaa aagagccaat cagcccatga tggaggattt
    10381 tgggatacag agaattttgt gtatgaagag tggttggaaa gcaatcagga acaggaaatg
    10441 gggattaatc tgcctgaagg atgggttcct gcaattcagt tagtggcttt ttctgagaaa
    10501 ggtcaagcag ttggatttct taatctccgg ttgcgcctca gtaactttct actagaagaa
    10561 ggtgggcaca ttggctactc catccgtcca tctgaaagag gcaagggtta tgcaaaagag
    10621 actctccgtc agggcttgca agttgctaag gaaaagaaca tcaagaaagc tctggtgacc
    10681 tgtagcgtga ataatcctgc tagcagagca gtcattctag caaatggtgg aatatttgag
    10741 gatgctcaca atggagtcga gcgttattgg atagaggtag cgaatgaata atccaaaacc
    10801 acaagaatgg aaaagcgagg aacttagtca aggtcgtatc attgactaca aggcctttaa
    10861 ctttgttgat ggcgaaggcg tgcgtaactc tctctatgta tcaggctgta tgtttcactg
    10921 cgagggatgt tataatgttg cgacttggtc ttttaatgct ggcattctct atacagcaga
    10981 attagaagag cagattatgg cagaccttgc ccaaccctat gttcaaggct tgactttgct
    11041 gggaggggag ccttttctta atactggcat tctcttgcct ctagttaaac gcatccgaaa
    11101 ggaattgcca gacaaggaca tttggtcctg gaccggctac acttgggaag aaatgatgtt
    11161 ggaaactcca gataaactgg aactcttgtc actgattgac attcttgtcg atggaagata
    11221 tgatcgaact aagagaaatc ttatgctcca gtttcgaggt tcgtctaacc aacgaattat
    11281 cgatgtgcaa aaatcgctca aaagtgggca agtagtgatt tgggacaagc tcaatgacgg
    11341 aaaagaaagc tatgaacagg tgaagagaga atgaagaaaa aggacttagt agaccaacta
    11401 gtctcagaga tcgagacggg gaaagtcagg acactgggaa tatacggtca tggagcttca
    11461 ggtaaatcaa cctttgcaca ggaattgtac caagctttag attctactac agtaaatttg
    11521 ctagagacag atccttatat cacctcagga cgccatctgg tagtacccaa ggacgcgccg
    11581 aatcaaaagg tgacagccag tctgccagtg gcgcatgaac tggagagttt gcagagagat
    11641 atccttgcct tgcaggcggg tatggatgtc ttgacaattg aagaaccttg gaaggctagt
    11701 gaggtcttgt ctggagccaa accaattttg attgtcgaag ggatgtctgt tggctttcta
    11761 cccaaggaac tctttgaaaa aaccatctgt ttctacacgg atgaggagac cgaattaaag
    11821 cgacgccttg ctagagatac gactgtgaga aatcgtgatg catcctttat attggctagc
    11881 catcagatga gacgggagca gtatctgcga tactataaag aaactgagtc taaggcggat
    11941 atcttagtgg atcaatcaga agataaattt gatgtcaaga ggacttaact tatgtataga
    12001 agaaatatag aagaaaatcc ctaattttag gaagaaaaag taggaaaaca gtttcatccc
    12061 aaaaaaacga aaaaacctaa caaatccctt gcaatcgcag gggatttgtg ttattctatt
    12121 atggtgctgt aaattacagc cttagttttg atacaagagg ttgcgacacg ctcggttgca
    12181 ttgccacgca acaccgtgtc ggttttcttg tggagctagc ctattatctt aaatagacga
    12241 aaaggagaaa aagatggcaa acaaaaaaat ccgtatccgt ttgaaagctt acgaacaccg
    12301 tacgcttgac acagcggctg caaaaatcgt agaatcagct actcgtacag gtgcacaagt
    12361 tgcgggtcca atcccacttc caactgaacg tagcctctac acaatcattc gtgcgactca
    12421 caaatacaaa gactctcgcg aacaatttga aatgcgtaca cacaaacgtt tgatcgatat
    12481 cgttaaccca actcaaaaaa cagttgatgc cttgatgaaa ttggatcttc caagtggtgt
    12541 aaacgtagaa atcaaacttt aatctaaaat ataaaagagc agaggctggt gtttcaatct
    12601 aattgaacac ggactaaact cggtgtgaaa aagataaact tcctattgtc cgttagacac
    12661 tgcgttagtt tcctattttc actttgagtt tgacgccctt tgtatcttag acttgagcat
    12721 aaaaaacgct cgttaaaaac tttttgaata aaaaatatag aaaaggaact attttctcat
    12781 gacaaaagga atcttaggga aaaaagtggg aatgactcaa atcttcactg aagctggcga
    12841 attgatccct gtaacagtta ttgaagcaac tccaaacgtt gttcttcaag ttaaaactgt
    12901 tgaaacagac ggatacaacg ctatccaagt tggtttcgat gacaaacgcg aagtattgag
    12961 caacaaacct gctaaaggac atgtagcgaa agctaacacg gctcctaagc gcttcattcg
    13021 tgaattcaaa aacgttgaag gcttggaagt tggcgctgaa atcacagttg aaacattcgc
    13081 agctggagat gttgttgatg taactggtac ttctaaaggt aaaggtttcc aaggtgttat
    13141 caaacgccac ggacaatcac gtggaccaat ggctcacggt tctcgttacc accgtcgtcc
    13201 aggttctatg gggcctgttg cacctaaccg cgtattcaaa ggtaaaaacc ttgcaggacg
    13261 tatgggtggt gaccgcgtaa caattcaaaa tcttgaagtt gtacaagttg ttccagaaaa
    13321 gaacgttatc cttatcaaag gtaacgtacc aggtgctaag aaatctctta tcactatcaa
    13381 atcagcagtt aaagctggta aataataaag aaaggggaaa tcagtcacaa tggcaaacgt
    13441 aacattattt gaccaaactg gtaaagaagc tggccaagtt gttcttaacg atgcagtatt
    13501 tggtatcgaa ccaaatgaat cagttgtgtt tgatgtaatc atcagccaac gcgcaagcct
    13561 tcgtcaagga acacacgctg ttaaaaaccg ctctgcagta tcaggtggtg gacgcaaacc
    13621 gtggcgtcaa aaaggaactg gacgtgctcg tcaaggttct atccgctcac cacaatggcg
    13681 tggtggtggt gttgtcttcg gaccgactcc acgttcatac ggctacaaac ttccacaaaa
    13741 agttcgtcgc ctagctctta aatcagttta ctctgaaaaa gttgctgaaa acaaattcgt
    13801 agctgtagac gctctttcat ttacagctcc aaaaactgct gaatttgcaa aagttcttgc
    13861 agcattgagc atcgattcta aagttcttgt tatccttgaa gaaggaaatg aattcgcagc
    13921 tctttcagct cgtaaccttc caaacgtgaa agttgcaact gctacaactg caagtgttct
    13981 tgacatcgca aatagcgaca aacttcttgt cacacaagca gctatctcta aaatcgagga
    14041 ggttcttgca taatgaattt gtatgatgtt atcaaaaaac ctgtcatcac tgaaagctca
    14101 atggctcaac ttgaagcagg gaaatatgta tttgaagttg acactcgtgc acacaaactt
    14161 ttgatcaagc aagctgttga agctgctttc gaaggtgtta aagttgccaa tgttaacaca
    14221 atcaacgtaa aaccaaaagc taaacgtgtt ggacgttaca ctggttttac taacaaaact
    14281 aaaaaagcta tcatcacact tacagctgat tctaaagcaa tcgagttgtt tgctgctgaa
    14341 gctgaataat ctaaggagga aatatcgtgg gaattcgtgt ttataaacca acaacaaacg
    14401 gtcgccgtaa tatgacttct ttggatttcg ctgaaatcac aacaagcact cctgaaaaat
    14461 cattgcttgt tgcattgaag agcaaggctg gtcgtaacaa caacggtcgt atcacagttc
    14521 gtcaccaagg tggtggacac aaacgtttct accgtttggt tgacttcaaa cgtaataaag
    14581 acaacgttga agcagttgtt aaaacaatcg agtacgatcc aaaccgttct gcaaacatcg
    14641 ctcttgtaca ctacactgac ggtgtgaaag catacatcat cgctccaaaa ggtcttgaag
    14701 taggtcaacg tatcgtttca ggtccagaag cagatatcaa agtcggaaac gctcttccac
    14761 ttgctaacat cccagttggt actttgattc acaacatcga gttgaaacca ggtcgtggtg
    14821 gtgaattggt acgtgctgct ggtgcatctg ctcaagtatt gggttctgaa ggtaaatatg
    14881 ttcttgttcg tcttcaatca ggtgaagttc gtatgattct tggaacttgc cgtgctacag
    14941 ttggtgttgt cggaaacgaa caacatggac ttgtaaacct tggtaaagca ggacgtagcc
    15001 gttggaaagg tatccgccca acagttcgtg gttctgtaat gaaccctaac gatcacccac
    15061 acggtggtgg tgaaggtaaa gcaccagttg gtcgtaaagc accatctact ccatggggca
    15121 aacctgctct tggtcttaaa actcgtaaca agaaagcgaa atctgacaaa cttatcgttc
    15181 gtcgtcgcaa cgagaaataa tattaaacta gtcgcttaag caactagtaa atccgccagc
    15241 tcggtagcgc tccataggag tgcaagccgc tgtggtacaa catttaaagg agaaaatata
    15301 aaaatgggac gcagtcttaa aaaaggacct ttcgtcgatg agcatttgat gaaaaaagtt
    15361 gaagctcaag ctaacgacga aaagaaaaaa gttattaaaa cttggtcacg tcgatcaacg
    15421 atcttcccaa gtttcattgg ttacactatt gcagtttatg acggacgtaa acacgtacct
    15481 gtttacatcc aagaagacat ggtaggccac aaacttggtg aatttgcacc aactcgtact
    15541 tacaaaggtc acgctgcaga cgacaagaaa acacgtagaa aataaggaga acataaatgg
    15601 cagaaattac ttcagctaaa gcaatggctc gtacagtacg tgtttcacct cgtaaatcac
    15661 gtcttgttct tgataacatc cgtggtaaaa gcgtagccga tgcaatcgca atcttgacat
    15721 tcactccaaa caaagctgct gaaatcatct tgaaagtttt gaactcagct gtagctaacg
    15781 ctgaaaacaa ctttggtttg gataaagcta acttggtagt atctgaagca ttcgcaaacg
    15841 aaggaccaac tatgaaacgt ttccgtccac gtgcgaaagg ttcagcttca ccaatcaaca
    15901 aacgtacagc tcacatcact gtagctgttg cagaaaaata aggaggtaaa atcgtgggtc
    15961 aaaaagtaca tccaattggt atgcgtgtcg gcatcatccg tgattgggat gccaaatggt
    16021 atgctgaaaa agaatacgcg gattaccttc atgaagatct tgcaatccgt aaattcgttc
    16081 aaaaagaact tgctgacgca gcagtttcaa ctattgaaat cgaacgcgca gtaaacaaag
    16141 ttaacgtttc acttcacact gctaaaccag gtatggttat cggtaaaggt ggtgctaacg
    16201 ttgatgcact ccgtgcaaaa cttaacaaat tgactggaaa acaagtacac atcaacatca
    16261 tcgaaatcaa acaacctgat ttggatgctc accttgtagg tgaaggaatt gctcgtcaat
    16321 tggagcaacg tgttgctttc cgtcgtgcac aaaaacaagc aatccaacgt gcaatgcgtg
    16381 ctggagctaa aggaatcaaa actcaagtat caggtcgttt gaacggtgca gatatcgccc
    16441 gtgctgaagg ctactctgaa ggaactgttc cgcttcacac acttcgtgca gatatcgatt
    16501 acgcttggga agaagcagat actacatacg gtaaacttgg tgttaaagta tggatctacc
    16561 gtggtgaagt tcttccagct cgtaaaaaca ctaaaggagg taaataacca atgttagtac
    16621 ctaaacgtgt taaacaccgt cgtgaattcc gtggaaaaat gcgcggtgaa gcaaaaggtg
    16681 gaaaagaagt agcattcggt gaatacggtc ttcaagctac aactagccac tggatcacta
    16741 accgccaaat cgaagctgct cgtatcgcca tgactcgtta catgaaacgt ggtggtaaag
    16801 tttggattaa aatcttccca cacaaatcat acactgctaa agctatcggt gtgcgtatgg
    16861 gatctggtaa aggggcacct gaaggttggg tagcaccagt taaacgtggt aaagtgatgt
    16921 tcgaaatcgc tggtgtatct gaagagattg cacgtgaagc gcttcgactt gctagccaca
    16981 aattgccagt taaatgtaaa ttcgtaaaac gtgaagcaga ataaggagaa ggcatgaaac
    17041 ttaatgaagt aaaagaattt gttaaagaac ttcgtggtct ttctcaagaa gaactcgcga
    17101 agcgcgaaaa cgaattgaaa aaagaattgt ttgaacttcg tttccaagct gctactggtc
    17161 aattggaaca aacagctcgc ttgaaagaag ttaaaaaaca aatcgctcgt atcaaaacag
    17221 ttcaatctga agcgaaataa tagactaggg aaggagaaat ttcaatggaa cgcaataatc
    17281 gtaaagttct tgttggacgt gttgtatctg acaaaatgga caagacaatc acagttgtag
    17341 ttgaaacaaa acgtaaccac ccagtctatg gtaaacgtat taactactct aaaaaataca
    17401 aagctcatga tgaaaacaat gttgccaaag aaggtgatat cgtacgtatc atggaaactc
    17461 gcccgctttc agctacaaaa cgtttccgtc ttgtagaagt tgttgaagaa gcggtcatca
    17521 tctaatcaaa cctgaaagga gaaaactgaa atgattcaaa cagaaactcg tttgaaagtc
    17581 gcagacaaca gcggtgctcg cgaaatcttg actatcaaag ttcttggtgg ttcaggacgt
    17641 aaatttgcaa acatcggtga tgttatcgtg gcatctgtaa aacaagctac tcctggtggt
    17701 gcggttaaaa aaggtgacgt tgttaaagca gttatcgttc gtactaaatc aggtgctcgt
    17761 cgtgctgatg gttcatacat caaatttgac gaaaacgcag cagttatcat ccgtgaagac
    17821 aaaactcctc gcggaacacg tatctttggc ccagttgcac gtgaattgcg tgaaggtggt
    17881 ttcatgaaga tcgtgtcact tgctccagaa gtactttaat ttttaggaac aaactagtcc
    17941 cctagcttca agctagggta cccttatggg cgtaagaaaa atcaaggaga aacctaatgt
    18001 ttgtaaaaaa aggcgacaaa gttcgcgtaa tcgctggtaa agataaggga acagaagctg
    18061 ttgtccttac tgcccttcca aaagtaaaca aagttatcgt tgaaggtgtt aacattgtta
    18121 agaaacacca acgtccaact aacgagcttc ctcaaggtgg tatcatcgag aaagaagcag
    18181 ctatccacgt atcaaatgtt caagttttgg acaaaaatgg tgtagctggt cgtgttggtt
    18241 acaaatttgt agacggtaaa aaagttcgct acaacaaaaa atcaggcgaa gtgcttgatt
    18301 aatcacgaag gaaaggagaa gtataatggc aaatcgttta aaagaaaaat atcttaatga
    18361 agtagttcct gctttgacag aacaattcaa ctactcatca gtgatggctg tgcctaaagt
    18421 agataagatt gttttgaaca tgggtgttgg tgaagctgta tcaaacgcta aaagccttga
    18481 aaaagctgct gaagaattgg cacttatctc aggtcaaaaa ccacttatca ctaaagctaa
    18541 aaaatcaatc gccggcttcc gtcttcgtga aggtgttgcg atcggtgcaa aagttaccct
    18601 tcgtggtgaa cgtatgtacg aattcttgga taaattggta tcagtttcac ttccacgtgt
    18661 acgtgacttc cacggtgttc caacaaaatc atttgatgga cgcgggaact acacacttgg
    18721 tgtgaaagaa caattaatct tcccagaaat caacttcgat gacgttgaca aaactcgtgg
    18781 tcttgacatc gttatcgtaa caactgctaa cactgacgaa gagtcacgtg cattgcttac
    18841 aggccttgga atgccttttg caaaataata taggaggtaa atctaatggc taaaaaatca
    18901 atggtagcta gagaggctaa acgccaaaaa attgttgacc gttatgctga aaaacgtgct
    18961 gcattaaagg cggcagggga ctacgaaggt ttatctaaat tacctcgcaa cgcctcaccg
    19021 actcgtttac ataatcgttg tagagttacg gggcgcccac attcagttta ccgcaaattt
    19081 ggtctgagtc gtatcgcttt tcgcgaactt gcgcataaag gtcaaattcc tggtgtaaca
    19141 aaagcatctt ggtaatttaa gatatcaaga gcgtcaaaac tccaagtaaa aataggaaac
    19201 ttgacgaaga aactaaagtt tctaggaaag tttatctttt tcacacagag tttagcccgg
    19261 gttcaattgg gcttgccaat ttgaacacga gctacagctt tggaaaaaaa gaccaatttg
    19321 ctttggagca ttgcttctgc attaaattgt ctatttttgc tcgtgctgtt acgctctttg
    19381 tatcatgtat taactagcaa gtgcaacttg caaactacta gtaagaggag aaaaacaaaa
    19441 tggttatgac tgacccaatc gcagacttcc taactcgtat tcgtaatgct aaccaagcta
    19501 aacacgaagt acttgaagta cctgcatcaa acatcaaaaa agggattgct gaaatcctta
    19561 aacgcgaagg ttttgtaaaa aacgttgaaa tcattgaaga tgacaaacaa ggcgtcatcc
    19621 gtgtatttct taaatacgga ccaaatggtg agaaagttat cactaacttg aaacgtgttt
    19681 ctaaaccagg acttcgtgtc tacaaaaaac gtgaagacct tccaaaagtt cttaacggac
    19741 ttggaattgc catcctttca acttctgaag gtttgcttac tgataaagaa gcacgccaaa
    19801 agaatgttgg tggtgaggtt atcgcttacg tttggtaaaa tcaagataca aagctcgtaa
    19861 agaacaaagc aaaattagga agttggagaa gtttgtttac aaacaagcca acttatctat
    19921 tttgcacagt tcttagagcg tgttcagttc agctcttgaa ctaaataagt atctgaaccc
    19981 cgtgaaaact ggccgttctg gcctgacaat ttaacaggag aaaataaaca tgtcacgtat
    20041 tggtaataaa gttatcgtgt tgcctgctgg tgttgaactc gctaacaatg acaacgttgt
    20101 aactgtaaaa ggacctaaag gagaacttac tcgtgagttc tcaaaagata ttgaaatccg
    20161 tgtggaaggt actgaaataa ctcttcaccg tccaaacgat tcaaaagaaa tgaaaactat
    20221 ccacggaact actcgtgccc ttttgaacaa catggttgtt ggtgtatcag aaggattcaa
    20281 gaaagaactt gaaatgcgtg gggttggtta ccgtgcacag cttcaaggat ctaaacttgt
    20341 tttggctgtt ggtaaatctc atccagacga agttgaagct ccagaaggaa ttacttttga
    20401 acttccaaac ccaacaacaa tcgttgttag cggaatttca aaagaagtag ttggtcaaac
    20461 agctgcttac gtacgtagcc ttcgttcacc agaaccatat aaaggtaaag gtatccgtta
    20521 cgttggtgaa ttcgttcgcc gtaaagaagg taaaacaggt aaataatgtt gagtggttga
    20581 tcatcaacca ccaacctatt ttccaacttt gtgcatagca cacgatttaa aactaaagag
    20641 gtgaaaactg tgatttcaaa accagataaa aacaaactcc gccaaaaacg ccaccgtcgc
    20701 gttcgcggaa aactctctgg aactgctgat cgcccacgtt tgaacgtatt ccgttctaat
    20761 acaggcatct acgctcaagt gattgatgac gtagcgggtg taacgctcgc aagtgcttca
    20821 actcttgata aagaagtttc aaaaggaact aaaactgaac aagccgttgc tgtcggtaaa
    20881 ctcgttgcag aacgtgcaaa cgctaaaggt atttcagaag tggtgttcga ccgcggtgga
    20941 tatctatatc acggacgtgt gaaagctttg gctgatgcag ctcgtgaaaa cggattgaaa
    21001 ttctaatagg aggacactag aaaatggcat ttaaagacaa tgcagttgaa ttagaagaac
    21061 gcgtagttgc tgtcaaccgt gttacaaaag ttgttaaagg tggacgtcgt cttcgtttcg
    21121 cagctcttgt tgttgttggt gaccacaatg gtcgcgtagg atttggtact ggtaaagctc
    21181 aagaagttcc agaagcaatc cgtaaagcag tagatgatgc taagaaaaac ttgatcgaag
    21241 ttcctatggt tggaacaaca atcccacacg aagttctttc agaattcggt ggagctaaag
    21301 tattgttgaa acctgctgta gaaggttctg gagttgccgc tggtggtgca gttcgtgccg
    21361 ttgtggaatt ggcaggtgtg gcagatatta catctaaatc acttggttct aacactccaa
    21421 tcaacattgt tcgtgcaact gttgaaggtt tgaaacaatt gaaacgcgct gaagaaattg
    21481 ctgcccttcg tggtatttca gtttctgatt tggcataaga aaggggataa aatggctcaa
    21541 attaaaatta ctttgactaa gtctccaatc ggacgcattc catcacaacg taaaactgtt
    21601 gtagcacttg gacttggcaa attgaacagc tctgttatta aagaagataa cgctgctatc
    21661 cgtggtatga tcacagcagt atctcactta gtaacagttg aagaagtaaa ctaatgaagt
    21721 tttaggggat gtgcactgta ccatccccta aaactagata tagtcatcta tgatgacatc
    21781 gtataggcga gttgatgggg gagacaacct tttctccctt atcggcgcta gcattttaca
    21841 aaagaggaga aaataaaaat gaaacttcat gaattgaaac ctgcagaagg ttctcgtaaa
    21901 gtacgtaacc gcgttggtcg tggtacttca tcaggtaacg gtaaaacatc tggtcgtggt
    21961 caaaaaggtc aaaaagctcg tagcggtggc ggagttcgcc ttggttttga aggtggacaa
    22021 actccattgt tccgtcgtct tccaaaacgt ggattcacta acatcaacgc taaagaatac
    22081 gcaattgtga accttgacca attgaacgtc tttgaagatg gtgctgaagt aactccagtt
    22141 gttcttatcg aagcaggaat tgttaaagct gaaaagtcag gtattaaaat tcttggtaac
    22201 ggtgagttga ctaagaaatt gactgtgaaa gcagctaaat tctctaaatc agctgaagaa
    22261 gctatcactg ctaaaggtgg ttcagtagaa gtcatctaag agaggtgacc tatgtttttt
    22321 aaattattaa gagaagctct taaagtcaag caggttcgat caaaaatttt atttacaatt
    22381 tttatcgttt tggtctttcg tatcggaact agcattacag ttcctggtgt gaatgccaat
    22441 agcttgaatg ctttaagtgg attatccttc ttaaacatgt tgagcttggt gtcggggaat
    22501 gccctaaaaa acttttcgat ttttgcccta ggagttagtc cctatatcac cgcttctatt
    22561 gttgtccaac tcttgcaaat ggatatttta cccaagtttg tagagtgggg taaacaaggg
    22621 gaagtaggtc gaagaaaatt gaatcaagct actcgttata ttgctctagt tctcgctttt
    22681 gtgcaatcta tcgggattac agctggtttt aataccttgg ctggagctca attgattaaa
    22741 actgctttaa ctccacaagt ttttctgacg attggtatca tcttaacagc tggtagtatg
    22801 attgtcactt ggttgggtga gcaaattaca gataagggat acggaaacgg tgtttccatg
    22861 attatctttg ccgggattgt ttcctcaatt ccagagatga ttcagggcat ctatgtggac
    22921 tactttgtga acgtcccaag tagccgtatc acttcatcta tcattttcgt aatcattttg
    22981 attattactg tattgttgat tatttacttt acaacttatg ttcaacaagc agaatacaaa
    23041 attccaatcc aatatactaa ggttgcacaa ggtgctccat ctagctctta ccttccgtta
    23101 aaggtaaacc ctgctggagt tatccctgtt atctttgcca gttcgattac tgcagcgcct
    23161 gcggctattc ttcagttttt gagtgccaca ggtcatgatt gggcttgggt aagggtagca
    23221 caagagatgt tggcaactac ttctccaact ggtattgcca tgtatgcttt gttgattatt
    23281 ctctttacat tcttctatac gtttgtacag attaatcctg aaaaagcagc agagagccta
    23341 caaaagagtg gtgcctatat ccatggagtt cgtcctggta aaggtacaga agaatatatg
    23401 tctaaacttc ttcgtcgtct tgcaactgtt ggttccctct tccttggtgt gatttccatt
    23461 ttaccgattg cagctaaaga tgtatttggt ctttctgatg ttgttgcctt tggtggaaca
    23521 agtctcttga tcattatctc tacaggtatc gaaggaatca agcaattgga aggttaccta
    23581 ttgaaacgta agtatgttgg tttcatggac agaacagaat aaaagtattt actgaatcag
    23641 taaatgctga gggagtggag gtttaaactc tgacatttgt aagagttgga tctcccctct
    23701 tctattttgt ttttaaatag gggtgaaaag actttttgct tctatttaaa aataaaataa
    23761 ggagatcaaa tcatgaatct tttgattatg ggcttacctg gtgcaggtaa gggaactcaa
    23821 gcagcaaaaa tcgtagaaca attccatgtt gcacatatct caacaggtga tatgttccgc
    23881 gctgcaatgg caaatcaaac tgaaatgggt gttcttgcta agtcatatat tgacaagggt
    23941 gaattggttc ctgacgaagt tacaaatgga atcgtaaaag aacgcctttc acaagatgat
    24001 attaaagaaa caggattctt attggatggt tacccacgta caattgaaca agctcatgcc
    24061 ttggacaaaa cattggctga acttggcatt gaactagaag gtgttatcaa tattgaagtg
    24121 aaccctgaca gcctcttgga acgtttgagt ggccgtatca tccaccgcgt aactggagaa
    24181 actttccaca aggtctttaa cccaccagtt gactataaag aagaagatta ctaccaacgt
    24241 gaagatgata agcctgagac agtaaaacgt cgtttggatg ttaatattgc tcaaggagaa
    24301 ccaatcattg ctcactaccg tgccaaaggt ttggttcatg acatcgaagg taatcaagat
    24361 atcaatgatg tcttctcaga tattgaaaaa gtattgacaa atttgaaata aagcgttttt
    24421 catacttgca aaaattcgct acaaatgtta tactgagata gtctgactta taattgttgt
    24481 ctctgtgtct agaggcatcg aatcgaaatt tatggaggtg cttttgcgtg gcaaaagacg
    24541 atgtgattga agttgaaggc aaagtagttg atacaatgcc gaatgcaatg tttacggttg
    24601 aacttgaaaa tggacatcag attttagcaa cagtttctgg taaaattcgt aaaaactata
    24661 ttcgtatttt agcgggagat cgtgttactg tcgaaatgag tccatatgac ttgacacgtg
    24721 gacgtatcac ttaccgcttt aaataatcga aaaacttgga gggataagaa atgaaagtaa
    24781 gaccatcggt caaaccaatt tgcgaatact gtaaagttat tcgtcgtaat ggtcgtgtta
    24841 tggtaatttg cccagcaaat ccaaaacaca aacaacgtca aggataagat agaaaggaga
    24901 aaacatggct cgtattgctg gagttgatat tccaaatgac aaacgcgtag taatctcatt
    24961 gacttatgtt tatggtatcg gacttgcaac atctaagaaa attttggctg ctgctggaat
    25021 ctcagaagat gttcgtgtac gtgatcttac atcagatcaa gaagatgcta tccgtcgtga
    25081 agtggatgca atcaaagttg aaggtgacct tcgtcgtgaa gtaaacttga acatcaaacg
    25141 tttgatggaa atcggttcat accgtggtat ccgtcaccgt cgtggacttc ctgtccgtgg
    25201 acaaaacact aaaaacaacg cccgcactcg taaaggtaaa gctgttgcga ttgctggtaa
    25261 gaaaaaataa tataggaggt aaaagtcttg gctaaaccaa cacgtaaacg tcgtgtgaaa
    25321 aagaatatcg aatctggtat tgctcatatt cacgctacat ttaataacac tattgttatg
    25381 attactgatg tgcatggtaa tgcaattgct tggtcatcag ctggtgctct tggtttcaaa
    25441 ggttctcgta aatctacacc attcgctgct caaatggctt ctgaagctgc tgctaaatct
    25501 gcacaagaac acggtcttaa atcagttgaa gttactgtaa aaggtccagg ttctggtcgt
    25561 gagtcagcta ttcgtgcgct tgctgccgct ggtcttgaag taacagcaat tcgtgatgtg
    25621 actccagtgc cacacaatgg tgctcgtcct ccaaaacgtc gccgtgtata atcatcgcat
    25681 tacactgctt ttcgtttaag agggagtaac taaatgatcg agtttgaaaa accaaatata
    25741 acaaaaattg atgaaaataa agattatggc aagtttgtaa tcgaaccact tgaacgtggc
    25801 tacggtacaa ctcttggtaa ctctcttcgt cgtgtacttc tagcttctct accaggagca
    25861 gctgtgacat ctatcaacat tgatggtgtg ttacatgagt ttgacacagt tccaggtgtt
    25921 cgtgaagacg tgatgcaaat cattctgaac attaaaggaa ttgcagtgaa atcgtacgtt
    25981 gaagacgaaa aaatcatcga actggatgtt gaaggtcctg ctgaagtaac agctggtgac
    26041 attttgacag atagcgatat tgaaattgta aatccagatc attatctctt tacaattggt
    26101 gaaggttctt ctctaaaagc gactatgact gttaacagtg gtcgtggata tgtacctgct
    26161 gatgaaaata aaaaggataa tgcaccagtt ggaacacttg ctgtagattc tatttataca
    26221 ccagttacaa aagtcaacta tcaagtggaa cctgctcgtg taggtagcaa tgatggtttc
    26281 gacaaattaa cccttgaaat cttgacaaat ggaacaatta ttccagaaga tgctttaggg
    26341 ctttcagcac gtattttgac agaacatctt gatttgttta caaatcttac tgagattgct
    26401 aagtcaactg aagtgatgaa agaagctgat actgaatctg acgaccgtat tttagatcgt
    26461 acgattgagg aactggactt gtctgtgcgt tcatacaact gtttaaaacg tgccggtatc
    26521 aatactgtgc atgatttgac agaaaaatct gaagcagaga tgatgaaagt acgaaatctt
    26581 ggacgcaaga gtttggaaga agtgaaactc aaactcattg atttgggtct tggattaaaa
    26641 gataaataaa ggaggaatac atggcttacc gtaaactagg acgcactagc tcacaacgta
    26701 aagcaatgct tcgcgatttg acaactgacc ttttgatcaa cgaatcaatc gtgacaactg
    26761 aagctcgtgc taaagaaatc cgtaaaactg ttgaaaaaat gattactcta ggtaaacgtg
    26821 gtgatttgca tgcacgtcgt caagcagctg ctttcgtacg taatgaaatc gcatctgaaa
    26881 actatgatga agcaactgat aagtacactt ctactacagc acttcaaaaa ttgttctcag
    26941 aaatcgcacc tcgttatgct gaacgtaacg gtggatacac tcgtatcctt aaaactgaac
    27001 cacgtcgtgg tgatgcagcg ccaatggcga tcatcgaatt agtataaaat catcaatttt
    27061 gttgagtgtt atgatgatgg agtcttgtgc tcttagtcta gctctggtct accgctagga
    27121 tttcggtcct agcgggaaca ctcatcataa gttgggatag tagacgcttg tttacgaaat
    27181 tgtttttttc ttaagaacaa cttcgtaagc aggcgttttt gagtattttc gttagaatta
    27241 tgctatacta tttgaaaaga atcctgttta atgttaaggt ttcttatttt aagaagaatt
    27301 ggagtttact tatgaaagcc attataactg ttgttggtaa agataaatct ggaattgttg
    27361 caggtgtttc tggtaaaatt gcagaattag gattgaatat tgacgatatc tctcaaactg
    27421 tcttggatga atattttacg atgatggctg ttgtatctag tgatgaaaag caagatttta
    27481 cctatcttcg taatgaattt gaagcttttg ggcaaacttt gaatgtaaaa atcaatattc
    27541 agagtgcagc gattttcgaa gctatgtata atatctagga ggtcatcatg gatattagac
    27601 aagttactga aaccatcgcc atgattgagg agcaaaactt cgatattaga accattacca
    27661 tggggatttc tcttttggac tgtatcgatc cagatatcaa tcgtgctgcg gagaaaatct
    27721 atcaaaaaat tacgacaaag gcggctaatt tagtagctgt tggtgatgaa attgcggctg
    27781 agttgggaat tcctatcgtt aataagcgtg tatcggtgac acctatttct ctgattgggg
    27841 cagcgacaga tgcgacggac tacgtggttc tggcaaaagc gcttgataag gctgcgaaag
    27901 agattggtgt ggactttatt ggtggttttt ctgccttagt acaaaaaggt tatcaaaagg
    27961 gagatgagat tctcatcaat tccattcctc gcgctttgac tgagacggat aaggtctgct
    28021 cgtcagtcaa tatcggctca accaagtctg gtattaatat gacggctgtg gcagatatgg
    28081 gacgaattat caaggaaacg gcaaatcttt cagatatggg agcggccaag ttggttgtat
    28141 tcgctaatgc tgttgaggac aatccattta tggcgggtgc ctttcatggt gttggggaag
    28201 cagatgttat catcaatgtc ggagtttctg gtcctggtgt ggtgaaacgt gctttggaaa
    28261 aagttcgtgg acagagcttt gatgtagtag ccgaaacagt taagaaaact gcctttaaaa
    28321 tcactcgtat cggtcaattg gttggtcaaa tggccagtga gagactgggt gtggagtttg
    28381 gtattgtgga cttgagtttg gcaccaaccc ctgcggttgg agactctgtg gcacgtgtcc
    28441 ttgaggaaat ggggctagaa acagttggca cgcatggaac gacagctgcc ttggccctct
    28501 tgaacgacca agttaaaaag ggtggagtga tggcctgtaa ccaggtcggt ggtctatctg
    28561 gtgcctttat ccctgtttct gaggatgaag gaatgattgc tgcagtgcaa aatggctctc
    28621 ttaatttaga aaaactagaa gctatgacgg ctatctgttc tgttggattg gatatgattg
    28681 ccatcccaga agatacgcct gctgaaacta ttgcggctat gattgcggat gaagcagcaa
    28741 tcggtgttat caacatgaaa acaacagctg ttcgtatcat tcccaaagga agagaaggcg
    28801 atatgattga gtttggtggt ctattaggaa ctgcacccgt tatgaaggtt aatggggctt
    28861 cgtctgtcga cttcatctct cgcggtggac aaatcccagc accaattcat agttttaaaa
    28921 attaagaaaa taggagaaat tttaagttct atttaagatt agatgtgtat actataatca
    28981 ttaaataaag acctcctaat attatttgaa acagataaca ctgaattagt ttgaatttga
    29041 ttttcatcta atatctttat ttaatgaact cctaaacttt ttcataataa tctccttcaa
    29101 aagtcgcctg tatgggtggc ttttatttta tcattcatga tataatagaa gcaaacggag
    29161 gacggaaaat ggtaaaagta cgattgtatt tggtacgtca tggcaagacc atgtttaaca
    29221 cgattggtcg cgcgcaaggt tggagcgata ctcccttaac tgctgaaggt gaacgaggga
    29281 ttcaagagtt aggaatcggt ttgcgagaat ctgatctaca gtttgagcgc gcttattcga
    29341 gtgattctgg tcgtaccatt cagaccatgg gaattatcct tgaagaactt ggcttgcagg
    29401 ggaaaatccc ttatcgcatg gacaagcgta tcagagaatg gtgtttcggt agttttgatg
    29461 gagcctatga tggcgatctt ttcatgggca ttattcctcg tatctttaat gtggaccacg
    29521 ttcaccaatt gtcttatgct gaactggctg agggcttggt agaggtcgat acagctggtt
    29581 gggctgaagg ctgggaaaaa ctcagtggcc gaatcaagga aggctttgaa atgattgcaa
    29641 aagaaatgga agatcaaggt ggaggtaacg cccttgttgt cagccatgga atgactattg
    29701 gaaccattgt ttatctgatt agtggcatgc atccgcatgg tctagataat ggtagcgtga
    29761 cgattcttga atatgaggac ggtcagttta gggttgaagt tgtcggtgac cgtagttacc
    29821 gagagctagg acgtgagaag atggaagaag gctctattta atcagtctag acttgcttgc
    29881 catgagctag ggatttgata agaatatcaa gataagaaaa aacagccgag ggtactcctt
    29941 tcggctgttt ttgatgtgga aaactaaagt gtaatgctat tgcttttaga gattttcata
    30001 aacaagagca aggaacctac tgttagaaca gtcaggatag ttgacaaggc tgcggctaca
    30061 ccgtaatttc ctctgagaac ctctgtataa atagctacag tcattgttct tgttttgaca
    30121 ttgtagagga ggatagaagt agagagtttt gaaatcattg tgacccaaga taagatggct
    30181 ccagaaatga taccagatag catcattgga gttgtaatct tagcaaaggt attgagacga
    30241 ctacttccta agctttcagc agcttcttca atacttggtg ctatttgttg taagctagca
    30301 acagatgagc gaatagtata cggtaatctt ctgacagata gagacataat caagatgaaa
    30361 gcagtccctg taatcataag aaatccactt ccaaatagac cagtattgaa ggaagaaatg
    30421 aaggcaatcc ctagaacggt tcctggtaca atataaggta ccatactgag gctgtcaatt
    30481 aagtttgtaa acaaattccg ttttctaacg gctaggtagg agataaatgt cgtaaataga
    30541 acaactagaa ctaaggcaat caaagggata cgaatggtat tgaaaatagc agatcccata
    30601 cgattgaaag ctaccttgta actgtttgga gaataacctt taacaaatac catacctgat
    30661 gtttttagga aagaggtata aattaagtag atttgaggta aaacagagat aaagataatt
    30721 ccgtagactg ttgcataaat ggcagccatt tttccttttg tagttttttt aggctcaatt
    30781 ggatggagca gattcatgct gaaactgtag cggtttgcaa tgtgtttttg gataaggaaa
    30841 attgccaagg caatgataat cgccataatt gcaaaagcag aatttcctcc aacctcgcta
    30901 ataaattggg tataaatcag gacagggaaa gtccgatatc cttcgccaat caacataggc
    30961 gttccaaagt ctgagaatgc tctcataaat acaagcaagg agctgctagt aaggttggaa
    31021 ctaggagagg taaaacaacc gttacgatag gtttaaatcc gaaggacccc atgctttcag
    31081 ctgcttcaag tagagaattg tcaatactgt tcattgttcc agcaacatat agaaatacca
    31141 gtgggaatag ttgcagtgta aagacaagta taattccttt gaatccataa atatcgatag
    31201 ctggaagata aagggcattt gtcaaaaatt tagtgatgac ctcatttcgt cccagcaaga
    31261 gaatccagga gtaggctcct acgaaaggag ttgacatgga agcaatgata atcaatattt
    31321 gtagaaattt cttccccttg aagtcataca tagagaagag ataagctaat agggttccta
    31381 caactaagga agtgacagta gcggtaatgg aaaccctgaa actgttgact agtgtctcag
    31441 agtagtaggc tttactaaag aaagtgacaa aattagctag tgagaattat ccttcatgta
    31501 taagtgctta cttgagcacg gtaacgatag gataaacgag aaagacaaga taggtaagaa
    31561 agatgaagaa agaggaggct gtccaaatat ttagtttttt acgttccatg gttgactcct
    31621 tttatcaggt tttgggaacc atctgcagaa aagatgttta atttttgcgt attgattcgt
    31681 agacgaatac gattgccttt ttgtagttct tcttcaaaag ttgattcttc actaacttga
    31741 atttttgagg caaaacctgt ctcaatgaaa tactccgtat ttagtccaag atagacgcta
    31801 tcgctaatag ttccttcaat atctccagat tcatctttga taaactcttc gggacgaatg
    31861 cttacatgaa tagcttgctc ctcaacctga tcaagagcta gcattcgaag ggcatagcca
    31921 tctgaaaaga cgatataagc gccgtcgctc cgtttttcaa gattggcagg gataatattt
    31981 gtgcgtccga taaaggttgc cacaaactca ttagctggtt tatgatagag ttcttttggt
    32041 cggccgattt gttggatcac cccatctttc ataacagcaa tttggtctga aatagccatg
    32101 gcttcttctt ggtcgtgggt tacataaaca gttgtaattc ccacttcgtg ttggatttct
    32161 cggatggctt gacgcatatc caagcgaagt ttggcctcca gattactaag tggctcgtcc
    32221 atgaggagaa cacttggatt aaccgctaag acgcatgcca aggtgacacg ttgttgttgt
    32281 ccaccactga gtttatcggg ctttcgatcc gcatattgag caatttgcat gagtccaaga
    32341 tacttgttgg tctgttgaat caattcttct tttggaacct tcttttgcat aagaccaaaa
    32401 gcaacgttgt ctcggacagt caaatgtggg aaaatagcgt agttttggaa aaccagcccg
    32461 atattgcgtt tgctgggttc catattattg atttttgtat catcgaagta aaattctcca
    32521 tctttgatac tgttgaaacc tgcaatcata cgaagaaggg tcgttttccc acatcctgaa
    32581 gctccaagaa gggtaaagag acttcctttt ggaattgtaa tgttcaaatt ctcaataaca
    32641 gggacatcgt ggtagatttt tttggcgtta ataatttcga tctcactcat agtgaacctc
    32701 ttttactgtt tagattggat atctgtaaag acttcgttgt atttcttaac gatatctgat
    32761 ttattcttga tgacataatc ataatcttca gtgagtgttt tgattttgtc aattggtttc
    32821 atgttttcgc ttgttttagc atttttaaga acaggacggt tagtagtggt tgtaccaagt
    32881 gtatcttgta cttcttgaga gataataaaa tcgataaatt tcttggcatt ttccatattt
    32941 ttagattttt taacgatagc agcactagca ggtaggaaga cggttccttc ttttggatag
    33001 actaccttaa tgttagctcc gtcatttaag agtttaactg ctggatcttc ataagagaga
    33061 ccaacagtca tttctccatc agcgactgct ttatagacac cagatgaact taaaccgatt
    33121 ttatagtata ttgaaactag aatagtacac atctacttct aaaacattgt tagaaatcga
    33181 tttgactgtc ctgattaatt tgtcttgttc ttatttcatt ttactatacc atcaataagt
    33241 gtgaaaagat cttttacata agaccaagcc ttatcatctt tgtaaccacc ttgagcttgt
    33301 agcatatttg ttaattgagc aaaggcgcta gaagagtttg ctgggtcagc agttgcgatt
    33361 tttcctttta gttcaggttt gagaaggtcg ctatatcctt cgatgttcat gcctttagtt
    33421 aaatcagggt ggacgattaa aacactacca tctagtgtat aaggagtaga gaagccagtt
    33481 gtgttttgat attctttgat aacattatca ttttcttttg aaatatagtt ttcaaagagt
    33541 tctccgtggg tagcatattg tgtataagaa ccaccaaaga taacatcagc tacaggaact
    33601 tctttttctg actctagttt tttgaaaagt tctccagtac cagcttgaat cagttctatt
    33661 ttgataccat atttttcttc aaaggcagga atagttgctc caattaagcc ttctgagttt
    33721 ggtcaataaa cgactagcga accaccgtct cctttatcag atgaactgtc atcggcagat
    33781 tcattagaag aacaagcagc ataatacatc catttctttt tcatgatgga tacctccgtt
    33841 gtgttattta agtttatttt aaaacaatgt aagcgttttt aaaacctaca attctattct
    33901 atagtgtatt gaatctataa cagtacactt tgactgctaa aatatttcta taaattaatt
    33961 tgactttcct gatagagatg ttcacatctt atttcaattc actatattag agtaaaattc
    34021 tctacaaaaa gaagaatagc ctattttact attcttccga gtaatttcaa ttcctttggg
    34081 gaaatatgga gatgcttttt aaatactttg gcaaaatatt tatagtctga aaatccaact
    34141 tggtcagaga tagcgcttaa aggggagttg ggagattcag ccatcttatc tatagcttgt
    34201 ttcaggcgat attgtaagat atattcattt agagtcatgg ggaagtcttc tttgataacc
    34261 ttatatagat gcttgttatc tgcaaatagc tagagcgttt caaggaaatg aactagaaat
    34321 aacaattaat atggtggttc agaaatacct tttgataatc aataagatct tcaggatgaa
    34381 gtgcgttgac tccatccatt tcatatttcc gatttaataa acgatatttg ttttcaccaa
    34441 attgatgaaa agggagtagt tgaacttggt cgatatttaa tgagttaaat agagtagcga
    34501 atttttctgc atcctctaaa ctattgttaa aattaggaat aactgggatt cttaaaacga
    34561 tagttttatt ttgagaaaaa gcataatgaa tgtttttaat aatcatttga ttaaaaaccc
    34621 cagtcacttt tttatgtttt atagaattat aatgttttag gtctgtgtag ataaaatcca
    34681 catattgaat taaatcaata aatttttcat gatcaacaaa ggcagtagtt tcaatggcag
    34741 tgtgtatgtg atgttcttta gctgatttta agatggcttt agcaaattca aactgagcaa
    34801 atatttcacc tcctgataaa gttaaacctc caccggattc ttcgtaaaat tctttgtctt
    34861 ttaatacctc tgtaataatt tcttctacag tcttttcttc accgactaag gtgaatttct
    34921 ctcgttgagc atctttcatt ttttcaggtt tcattctttg agattcagga ttagaacacc
    34981 atggacagcg cagaggacat ccttttaaaa aaacagttgt acgaataccc ggaccgtcat
    35041 gaattgaaaa gtgttgaata ttaaaaataa ttcctttaga tatttccata agagttcctc
    35101 ctcttcataa gtctatccta tcacaaaaac gaaagaaaaa caattacgaa cgaaaggtta
    35161 atttgttgtt ttttgctttt tattttggta gaataaaacg gaggtgtaaa atgaaaagat
    35221 tggaacaaat tattaaatta gtatcagaat atgaaaagat cgacgttaat acattatcgg
    35281 aaaaattaaa tgtatcgaaa gtaacgatta gaaaagattt agataaatta gagtcaaaag
    35341 gtttattaca cagagagcat ggatatgctg tattaaatag tggagatgac ttaaatgtac
    35401 gtttgtcaat taattatgaa actaagagaa aaattgttca ggaagcagta aaattggtgt
    35461 cagataatga aacaataatg atagaatctg gatcgacctg tgctttactt gctgaggaaa
    35521 tttgcaagca aaaaagaaat gttacgattg taacaaattc gttttttata gcaaattttg
    35581 tgagagctta tgattcatgt cgtgttattg ttcttggtgg tgagtttcag aaagattcac
    35641 aggtgactgt aggaccttta ttaaaagaaa tgatacagac ttttcatgtg tgtcaagctt
    35701 ttgttgggac agatggttac gataaagaga tgggctttac cggaaaagat ttaatgcgca
    35761 gtgaggtagt tcaatatatt tcagcagtgt cggataaagt cattgtccta actgactcaa
    35821 gtaaatttga taaaagaggt acagtaagaa gatttgcttt aagtcaagtc tatgaagtaa
    35881 taacagacga aaaactttct aaacaaaata tagctacatt agaaaatgct gggataatgg
    35941 ttaaggtagt ttcgtaagag gttaagtgta tgaatcaaga taggaataaa ctgctttcta
    36001 aaattgctta tctgtattat attgaaaact taaatcagtc acaaatagca gcaaaattag
    36061 gaatttatag aacctctatt agtagaatgt taacagaagc aaggaatgta ggaattgtta
    36121 aaattgaaat agagaatttt gataccaata tgtttaagtt ggaaaattat gtaaaagaaa
    36181 aatacagttt ggaaagttta gaaattattc caaatgaatt tgatgatact ccaacaattt
    36241 tatctgaaag aatttctcaa gttgcagcag gcgtccttag gaatctaatt gatgataata
    36301 tgaaaattgg cttttcttgg gggaaaagtt taagtaattt agtagattta attcacagta
    36361 aaagtgtccg aaatgttcac ttctatcctc tagcaggtgg tcctagtcac atacacgcta
    36421 aataccatgt gaatacactg atttatgaaa tgtctagaaa atttcatgga gagtgtacat
    36481 ttatgaatgc aacgattgtg caagaaaata aattgttagc agatggtatt ttgcaatcaa
    36541 gatattttga aaatttgaaa aatagttgga aagatttaga tatagctgta gtcggaattg
    36601 gtgattttag caataaaggg aaacatcaat ggttagacat gcttacagag gatgacttta
    36661 aagaattgac caaagttaaa actgtaggag aaatttgttg tcgatttttt gattcaaaag
    36721 gtaaagaagt ctatgaaaac ttacaggaaa gaacgatagc catctctttg gaagatttaa
    36781 aaaatattcc tcaaagttta gctgttgctt acggtgatac gaaagtatct tcgattcttt
    36841 ctgtcttgcg tgctaattta gtaaatcatt tgattacaga taaaaataca attttaaaag
    36901 ttttggaaga agatggtgat ttgactttta gagagattct aggtgagtga aaatgataga
    36961 ctgatcagtt tatcgttttt tctttttagt cgattgcaca tttgtgctta tataaacaaa
    37021 aatagtttat ctgttgtttt tggattgaca actttattat gtagttgtat tctatagtta
    37081 caaaagaaaa ttttaaaatt tcaaatgaaa aaagcttttt acatagtgaa atgaggagga
    37141 atttatggaa attattgttc cagatcaaat tatcatgggt ttaattttat atgctggcga
    37201 tgcgaaacaa catatttata aagcattaga ttacataaag aacggtacat gtgaacgatg
    37261 tgaagaagaa atccagttag ctgatgccgc cttattagaa gctcataatc tacaaacaaa
    37321 attcttggca caggaagcgt ctggtacaaa gacagaaatt acagctctct ttgttcattc
    37381 acaagatcat ctcatgacta gtatgacgga gattaattta atcaaagaaa ttattagttt
    37441 gagaaaagaa cttcataaaa aataatacta gagtattatc attgttatta acatagagga
    37501 ggaaaacata atggtgaaga ttggtttgtt ttgtgcagca ggtttttcta ctggtatgct
    37561 tgtaaataat atgaaaattg cagcgcaagc tagtggagtt gaggcagaaa tagaggcgtt
    37621 ttctcagtct aaattagcgg attatgcgcc aaatatagat gttgcactat tgggtccaca
    37681 agttgcttat acattagata aatcaaaaga aatttgtgat aagtgtgatg ttccgatagc
    37741 tgttattccg atgatggact atggtatgtt agatgggaaa aaagtattag atttggccct
    37801 atctttgatt agtgggtaag aaaaggagat ttattatgtc aaagatggat gttcagaaaa
    37861 tcattgcacc gatgatgaag tttgtgaata tgcgtggcat tatagctcta aaagatggga
    37921 tgttagcaat tttgccattg acagtagttg gtagtttgtt cttgattatg ggacaattgc
    37981 cgttcgaagg attaaataag agcattgcta gtgtttttgg agctaattgg acagagccgt
    38041 ttatgcaagt atattcagga acttttgcta ttatgggtct aatttcttgt ttttcaattg
    38101 cctattctta tgctaagaat agcggagtag aggctttacc agctggagtt ctatctgtat
    38161 ctgcattctt tattttgcta agatcatctt atatccctaa acaaggtgag gcgattgggg
    38221 acgctattag taaagtttgg tttggaggcc aaggaattat cggtgctatc attataggtt
    38281 tggtagtagg aagtatttat accttcttta taaagagaaa aattgttatt aagatgccag
    38341 aacaagttcc acaagctatt gccaaacagt ttgaagcaat gattccagca tttgtaattt
    38401 tcttatcttc tatgattgta tatattttag cgaagtcatt gactaatggc ggaacattca
    38461 tagaaatgat ttattctgct attcaagttc cgttgcaagg tttaactgga tctttgtatg
    38521 gtgctattgg aattgcattc tttatatcat ttttgtggtg gtttggtgtt catgggcaat
    38581 cggtagtaaa tggagtagtg acagctctgc ttttatctaa tcttgatgct aataaagcta
    38641 tgttagcctc tggtaatcta tcattagaaa atggtgcaca tattgttact caacaatttt
    38701 tagattcatt tttaattcta tcaggttcag ggattacgtt tggtcttgta gttgccatgc
    38761 tttttgcagc aaaatcaaaa caataccaag ccttaggaaa agttgcagct tttccagcaa
    38821 tatttaacgt aaatgagcca gttgtatttg gatttccgat tgtcatgaat ccagttatgt
    38881 ttgtaccttt cattcttgtt cctgtacttg cagctgtgat agtatatgga gctattgcaa
    38941 caggtttcat gcaaccattc tcaggggtaa cattgccttg gagtacacca gctattctat
    39001 caggattttt ggtgggtgga tggcaaggtg ttgtgactca gttattagta ttggtgatat
    39061 ctacagtggt ttactttcca ttctttaaga tacaagatcg tttagcttac caaaatgaaa
    39121 tcaaacaatc ttagaggtat ttgtgtgtta ctgttaaact cacacatttg tgctaaaaat
    39181 tagagagtta aaatttttct agttaaaagc ttgaaaattt ctataaaaat cggtattata
    39241 ttttcgaaag aaaggtgctt acgatggtaa atacagaagt agcaagaaca acaatcaaga
    39301 cagaatattt tggcagcctt actgaaagga tgaacaaata tcgagaagat gttttaaata
    39361 aaaaacctta tattgatgct gagagagcag ttctagcaac acgcgcctat gaacgataca
    39421 aggaacaacc taatgtccta aaacgtgcat atatgctgaa agaaattttg gaaaatatgt
    39481 ctatctatat tgaagaagaa tctatgattg cgggaaatca agcttcttcc aataaagatg
    39541 ctcctatttt tccggaatat acgctagaat ttgttctcaa tgagttggat ctttttgaaa
    39601 agcgtgatgg agatgttttc tatattacag aagaaacaaa agaacaactt agaagtattg
    39661 ctccgttttg ggaaaataat aatttacgtg ctagagctgg tgccttatta cctgaagaag
    39721 tgtctgttta tatggaaaca ggattcttcg gtatggaagg taagatgaat tctggagatg
    39781 ctcacttagc agttaactat cagaaacttt tgcaatttgg tttaagaggt tttgaagagc
    39841 gggctcgtaa agcaaaagta gctctagatt taacagatcc agcaagtatt gataaatatc
    39901 atttttacga ctctatattt atcgtaatcg atgctattaa agtatatgca aagcgctttg
    39961 ttgctcttgc taaaagttta gccgaaaatg caaatcctaa acgtaagaaa gaattacttg
    40021 agattgcaga tatttgctct agagtcccat atgaaccggc aactactttt gcagaagcta
    40081 ttcaatcagt ttggtttatt caatgtattt tacaaattga atctaatggc cactctcttt
    40141 catatggccg ttttgatcaa tatatgtatc catatatgaa ggctgattta gaaagtggta
    40201 aagaaacaga agatagcatt gttgaacgtc tgacaaatct ttggattaag acaattacaa
    40261 ttaataaggt tcgcagtcaa tcacatacat tttcttcagc aggaagtcct ttatatcaaa
    40321 atgttacaat tggtggacag actcgagata agaaggatgc tgttaaccca ttatcttatt
    40381 tggtcttaaa atcagttgca caaacccatc taccgcaacc taatctaact gtacgttacc
    40441 atgcaggttt agatgctcgt ttcatgaatg agtgtattga agtgatgaaa cttggttttg
    40501 gtatgcctgc atttaataat gatgagatta ttattccttc ttttattgca aaaggagtat
    40561 tggaagatga tgcttatgat tacagtgcca ttggatgtgt tgaaacggca gttccaggga
    40621 aatggggcta tcgttgcaca ggtatgagtt atatgaactt ccctaaggtt ctacttatca
    40681 cgatgaatga tggaattgat ccggcttcgg gtaaacggtt tgcaccaagc tttggtcatt
    40741 ttaaggatat gaagaacttt tctgaattag aaaatgcttg ggataaaaca ctaagatatt
    40801 tgacacgaat gagtgttatt gttgaaaatt ctattgattt atcattggaa cgagaagttc
    40861 ctgatattct atgttcagca ttgactgatg attgtattgg tcgtggaaaa caccttaaag
    40921 aaggtggagc agtatatgat tatatatcag gattgcaagt tggaattgca aatttgtcgg
    40981 attcattagc tgcaattaaa aaattggtgt ttgaggaaga acgtataagc ccaagtcagc
    41041 tttggcatgc actggaaaca gattatgccg gagaagaagg taaggtcatt caagaaatgt
    41101 tgattcatga tgcacctaag tatggtaatg atgatgatta tgctgacaaa ttggttactg
    41161 ctgcttatga catttatgtt gatgaaattg ctaaatatcc taatacacgt tatggaagag
    41221 gtccaattgg aggaattcgt tattcaggaa catcttctat ctcagccaac gtagggcagg
    41281 gacgtggaac attagcaact ccagatggac gcaacgcggg tacaccgtta gcagaggggt
    41341 gttcaccatc acataatatg gatcaacacg gccctacatc tgttttaaaa tctgtttcaa
    41401 aattaccaac agatgaaatc gtaggtgggg ttctcttaaa tcagaaagta aatcctcaaa
    41461 cgttagccaa agaagaagat aaattaaaac taattgcttt gttacgaaca ttctttaatc
    41521 gtttacatgg gtaccatatt caatacaatg ttgtttccag agagacgctg attgacgctc
    41581 agaaacatcc tgaaaaacac agagacttaa ttgttcgtgt tgcaggatac tctgcattct
    41641 tcaatgttct ttctaaggca acccaagatg acattatagg acgtactgag catactttgt
    41701 aaaataaaga ggttcttttt atggaattta tgcttgacac attaaattta gatgagatta
    41761 aaaagtggtc tgaaattttg ccgctagctg gggtaacttc aaatcccact attgcaaaaa
    41821 gagagggttc tattaatttt tttgaacgaa tcaaagatgt aagagaattg attggctcta
    41881 caccctctat tcatgttcag gtgatttctc aagattttga aggcatctta aaggatgctc
    41941 ataaaattcg aagacaagca ggagatgata tatttatcaa agtacctgtt actccagctg
    42001 gattacgtgc aataaaggcg ctaaaaaaag agggctacca tatcactgca acagctattt
    42061 atacagttat tcagggatta ttagctatcg aagcaggagc ggattaccta gctccatatt
    42121 ataatagaat ggaaaatctg aacattgatt caaattctgt cattcgtcaa ttagctcttg
    42181 ctattgatag acagaactct cctagtaaga ttttagctgc atcctttaaa aatgtagcac
    42241 aagtaaataa tgctttagct gcaggtgcgc atgctgttac agcaggagca gatgtttttg
    42301 aatcagcttt cgccatgcca tctatccaaa aggcggttga tgatttttct gacgattggt
    42361 ttgttactca aaatagtcgt tccatttaga tagagaggaa atacatatga gaatttttgc
    42421 tagtccttct agatatattc agggggaaaa tgccttgttt gaaaatgcca aatcaatttt
    42481 ggatttggga aattacccga ttctattatg cgatcagttg gtttatgata ttgttggaaa
    42541 acgatttgaa gattatctac ataggtatgg tttccatatt gttctggcgc tatttaatgg
    42601 tgaagcttct gacaatgaaa tcaatcgagt tgttgccttg gctgagaaag aaaattgtga
    42661 tagtattatc ggtcttggtg ggggaaagac gattgatagc gcaaaagcta ttgcagattt
    42721 gattgaaaag cctgttatta ttgctccaac aattgcatcg accgacgcac ctgtatctgc
    42781 tttatctgtt atttatacag atgaaggtgc atttgatcat tatctatttt attctaaaaa
    42841 tccagattta gttttggttg atacaaaagt tatttcacaa gcccctaagc gtttattagc
    42901 gtctggtatt gcagatggtt tagcaacttg ggttgaggcg cgtgcggtta tgcaggcaaa
    42961 tggaaaaact atgttgggac aacagcaaac attggctgga gttgcaattg cgaagaaatg
    43021 tgaagaaacg ctgtttgcag atggtttaca ggctatggca gcttgtgaag ctaaagtggt
    43081 gacaccagca ttagaaaata ttgttgaagc taatacttta ttgagtggtc taggttttga
    43141 aagtggagga ttagctgcgg cgcatgcaat tcataatggt tttactgcat tgacaggtga
    43201 cattcatcat ttaacacatg gtgaaaaagt agcttatgga actttagtac aactattatt
    43261 ggaaaataga cctaaagaag aacttgataa gtatattgag ttttacaaaa aaattggtat
    43321 gccaacaact ctaaaagaaa tgcatttgga tcaagttgga tatgatgatt taataaaagt
    43381 tggtaaacaa gcaactatgg agggtgagac aattcatcag atgccgttta agatttcgcc
    43441 ttcagatgtt gctcaagcta ttatcgctgt agatgcctat gtaaattcaa aataaacaat
    43501 aaggactact gttttccaaa tggtagtctt ttattgatcc ctgtattgaa ttctatagaa
    43561 gattgaaata ggatgagaac aaatcgattg ggaaagtaaa attaatttct ataaatgttt
    43621 tagcaattgt ttcgtactat ttcagattca gtctactata cgttcttcat aaatcaaaaa
    43681 gcgacatagg tagtcggcta tttattgtga atacattaat tagcattcca gttttatctt
    43741 cggtctaaaa taagtatttt gtgctatacg agataagctt cttgacttac tccttgattt
    43801 actgcataac aatgggataa aaagtgggag atagagcaat tcatagtcat caaaattaat
    43861 gagatacagt atacagtttt tcctttaaac acatttcaaa ttccctcaaa aatggtataa
    43921 tagtaacatc acaaaattgg agagagacca tgagttttta caatcataaa gaaattgagc
    43981 ctaagtggca gggctactgg gcagaacatc atacatttaa gacaggaaca gatgcatcaa
    44041 aacctaagtt ttatgcgctt gatatgttcc cttatccgtc tggagctggt ctgcacgtag
    44101 gacacccaga aggttatact gcaaccgata tcctcagtcg ttacaaacgt gcgcaaggct
    44161 acaatgttct tcacccaatg ggttgggatg cttttggttt gcctgcagag caatacgcta
    44221 tggatactgg taatgaccca gcagaattta cagcggaaaa cattgccaac ttcaaacgtc
    44281 aaatcaatgc gcttggattt tcttatgact gggatcgtga agtcaacaca acagatccaa
    44341 actactacaa gtggactcaa tggattttca ccaagcttta cgaaaaaggc ttggcctatg
    44401 aagctgaagt gccagtaaac tgggttgagg aattgggaac tgccattgcc aatgaagaag
    44461 tgcttcctga cggaacttct gagcgtggag gctatccagt tgtccgcaaa ccaatgcgcc
    44521 aatggatgct caaaattacg gcttacgcag agcgcttgct caatgactta gatgaactag
    44581 attggtcaga gtctatcaag gatatgcaac gcaactggat tggtaaatca actggtgcca
    44641 atgtaacttt caaagtaaaa ggaacagaca aggaatttac agtctttact actcgtccgg
    44701 acacactttt cggtgcgact ttcactgtct tggctcctga acatgaatta gtagacgcta
    44761 tcacaagttc agagcaagca gaagctgtag cagactataa acaccaagcc agccttaagt
    44821 ctgacttggc tcgtacagac cttgctaaag aaaaaactgg tgtttggaca ggtgcctatg
    44881 ccatcaaccc tgtcaatggt aaggaaatgc caatctggat tgcggactat gttcttgcta
    44941 gttatggaac aggtgcggtt atggctgtgc ctgcccacga ccaacgtgac tgggaatttg
    45001 ccaaacaatt tgaccttcca atcgtcgaag tacttgaagg tggaaatgtc gaagaagctg
    45061 cctacacaga ggatggcctg catgtcaatt cagacttcct agatggattg aacaaagaag
    45121 acgctattgc caagattgtg gcttgcttgg aagaaaaagg ctgtggtcag gagaaggtta
    45181 cctaccgcct ccgcgactgg ctctttagcc gtcaacgtta ctggggtgag ccaattccaa
    45241 tcattcattg ggaagatgga acttcaacag ctgttcctga aactgaattg ccgcttgtct
    45301 tgcctgtaac caaggatatc cgtccttcag gtactggtga aagtccacta gctaacttga
    45361 cagattggct tgaagtgact cgtgaagatg gtgtcaaagg tcgtcgtgaa actaacacca
    45421 tgccacaatg ggctggttca agctggtact acctccgcta tattgacccg cacaatactg
    45481 agaaattggc tgatgaggac ctcctcaaac aatggttgcc agtagatatc tacgtgggtg
    45541 gtgcggaaca tgctgtactt cacttgcttt atgctcgttt ctggcataaa ttcctctatg
    45601 acctcggtgt tgttccgact aaggaaccat tccaaaaact ctttaaccaa gggatgattt
    45661 tgggaacaag ctaccgtgac caccgtggtg ctcttgtggc aaccgacaag gttgaaaaac
    45721 gtgatggttc cttctttcat atagaaacag gggaagagtt ggagcaagcg ccagccaaga
    45781 tgtctaaatc gctcaagaac gttgttaacc cagatgatgt ggtggaacaa tacggtgccg
    45841 atacccttcg tgtttatgaa atgtttatgg gaccactcga tgcttcgatt gcttggtcag
    45901 aagaaggttt ggaaggaagc cgtaagttcc ttgaccgagt ttaccgtttg attacaagta
    45961 aagaaatcct tgcggaaaac aatggtgctc ttgacaaggc ttacaacgaa acagtcaaag
    46021 ctgttactga gcaaattgag tctctcaaat tcaacacagc tattgcccaa cttatggtct
    46081 ttgtcaatgc tgctaacaag gaagataagc tttatgttga ctatgccaaa ggctttattc
    46141 aattgattgc accatttgca cctcacttgg cagaagaact ctggcaaaca gtcgcagaaa
    46201 caggtgagtc aatctcttat gtagcttggc caacttggga cgaaagtaaa ctggttgaag
    46261 acgaaatcga aatcgttgtc caaatcaaag gtaaagtccg tgccaaactc atggttgcta
    46321 aagatatatc acgtgaagaa ttacaagaaa tcgctttagc tgatgaaaaa gtcaaagcag
    46381 aaattgacgg taaggaaatc gtgaaagtaa ttagtgtacc aaataaattg gttaatattg
    46441 ttgtaaaata accaatttat ttgctgattt ccaacctcaa acagtttccc aaactgtttg
    46501 agccaactaa actcgttaat atcgttgtga aataaggtag gaatccttca gagtagaatc
    46561 tggaggattt tttgaatctt cttatgaaag tatggtatac tatgggcaac tataaagttt
    46621 gaaaagtgaa aaaaggagaa agctatgcca gtaaatgaat atggtcaaat gattggggag
    46681 tcaatggaag gttatacacc aggtgagctg acttctattg aactcttaga agggcgttat
    46741 gctaggatag aggctctttc agtggaaaag catgcggagg atttgctagc tgtttatggg
    46801 cctgatacgc ctcaggagat gtggacctac ctctttcagg agccagtagc agacatggag
    46861 gagctggtca gccttttata gtaaaatgaa ataagaacag gacaaatcga tcaggacagt
    46921 caaatcgatt tctaacaatg ttttagaagt ataagtgtac tattttagtt tcaatttact
    46981 ataaatcaga tgttggctcg taaggaccgt ttttactaca tagacaaggc aactggtaag
    47041 gctttgggaa ctttttctct catgcgtatt gaccagtaac ggagtaatag aagtgggagc
    47101 tgtcactttt tctccaaaac tcagggggac acggataggg acagaagccc agtatctact
    47161 ggctcgctat gtctttgaag agcttaacta tcgtcgttat gagtggaaat gcgatgctct
    47221 taacctgcca tccagacgtg ctgcggagcg tttgggcttt atttatgaag gaaccttccg
    47281 tcaggcagtg gtttataagg ggcgtacgag agatatggat tggttgtcta tgattgataa
    47341 ggactggccc aaagtcaaag atcgtttgga aacatggttg cgtcctgaaa attttgataa
    47401 aaatggacag cagtacaaga gcttgagaga actttaagag gtgttgagat gattactatt
    47461 aaaaagcaag aaattgtcaa gctagaggat gttttacatc tctatcaggc tgtcggttgg
    47521 acaaattata cccatcaacc agagatgctg gagcaggcct tatctcattc attagtaatt
    47581 tatctggcac ttgatggtga tgctgtggtg ggcttgattc gtttggttgg agatggattc
    47641 tcatcagtat tggttcagga tttaatcgtt ttaccaatct atcagcgtca aggaattggt
    47701 agtgccttga tgaaagaggc tttagaggat tacaaagatg cctatcaagt ccagctggtg
    47761 acagaacaga cagaaagaac cttgggcttc tatcgttcta tgggctttga aatcttatcc
    47821 acctataatt gtatagggat gacttggatg aatcgtaaaa aataacaaaa cttgtttttt
    47881 cttaagcaaa atttaaggat ggtctagtat tatatagtca ttaaataaag acctcctaac
    47941 tttatttaat aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa
    48001 tcaggtggag ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt
    48061 cgatattttt cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga
    48121 atataactaa gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa
    48181 gtgactgtta attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg
    48241 cgtattaaat gagaagtgac atgtaagatt gtctcttcgt ttacgaaatc aaaatttcta
    48301 tgaaattgat agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg
    48361 aagaaaatgt aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt
    48421 actagttcta tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt
    48481 cttttttgac actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg
    48541 accacaattg gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc
    48601 tttcgtaggc ggtgtagcag tgtcgtagaa tattatacca cataagtgct aaacttagga
    48661 gtcacccaat caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg
    48721 agtagaattt tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt
    48781 cctcagtatt tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt
    48841 attgaagctg ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca
    48901 ggtctcggga aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag
    48961 cagacgtcgg gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta
    49021 gagcctgggg atgtactttt tattgatgag atccatcgtt tgccaatgtc agtggaagag
    49081 gtgctttata gtgctatgga ggacttctac atagatatta tgattggggc tggtgagggt
    49141 agtcgtagtg ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct
    49201 ggtatgctct ccaatccgct acgggcacgt tttgggatta caggccatat ggagtattat
    49261 gcccatgctg acttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc
    49321 actcatgagg cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat
    49381 cgtctcctca agcgcgtgcg cgattttgcc cagataatgg ggaatggggt aattgatgat
    49441 attattaccg ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg
    49501 gatcaaaaaa tccttcgtac catgattgag atgtacagtg gaggacctgt tggtctagga
    49561 actctttctg tgaatatcgc cgaagagcgt gagacagttg aagatatgta tgagccttac
    49621 ttgattcaaa aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca
    49681 tatgagcact taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag
    49741 agaaaatcca gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc
    49801 gtggttggca gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc
    49861 ttttgatcat gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga
    49921 aaccttatta ctggagaaaa agctgtgaga ggattttcct cagtaccagt gggaattgaa
    49981 aaatcaggtc tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga
    50041 tgctatgagt aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc
    50101 agattttgaa ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc
    50161 aactcctcat ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa
    50221 gaaaaattgg caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa
    50281 gctagggagt gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact
    50341 ttttcataat aatctcccta taaaaataaa gtcgcccaat caggcggctt atttttttga
    50401 aaaatgggct tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg
    50461 gtataatgaa acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa
    50521 gataaggctg tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg
    50581 gatggcaatg gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acataaggcg
    50641 ggcatggaag cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt
    50701 acggtctatg ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc
    50761 atgaacttgc cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt
    50821 aagattcaaa tgattgggga gacagaccgc ctgcctaagc aaaccttcga agctttaacc
    50881 aaggctgagg aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat
    50941 ggtggacgtg ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc
    51001 aaaatcaacc caggtgacat cacagaggaa ttgattggta actatctctt tacccagcat
    51061 ttgcctaagg acttacgaga cccagacttg attatccgta ctagtggaga attgcgtttg
    51121 agcaatttcc ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg
    51181 cctgattttg acgaagcggc cttgcaggaa gctattcttg cctataatcg tcgccatcgc
    51241 cgatttggag gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg
    51301 cagggattgc cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga
    51361 tagcaatcgg aatcatagcc atgctagcca tgcatgaact tttgaagatg agaggtctag
    51421 agaccatgac gatggagggc ctcttgaccc tctttgcaac ctttgtattg accattcccc
    51481 tggaaaatta cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga
    51541 tttcaatcat gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt
    51601 tccctcttgc tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg
    51661 ttgcaggttt ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg
    51721 cctatcttgt tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata
    51781 aaacccttga gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta
    51841 tgatagttga cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta
    51901 ttttctttag cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt
    51961 ttggtgttaa ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg
    52021 atagtatgtt gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg
    52081 gaggaaacgc tatgctcgga attttaacct ttattctggt ttttgggatt attgtagtgg
    52141 tgcacgagtt cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg
    52201 ccatcggtat gggacctaaa atctttgctc acattggcaa ggatggaacg gcctatacca
    52261 ttcgaatctt gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg
    52321 aaatcaagac aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca
    52381 tcaatctctc aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg
    52441 attttgaaga caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag
    52501 tggatcacga tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag
    52561 atgttcaata tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggtccta
    52621 tgaacaattt tatcttaggt gttgttgttt tttgggtttt aatctttatg cagggtggtg
    52681 tcagagatgt tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag
    52741 gagtaccaga aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa
    52801 gcttgatcca agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga
    52861 ctatttctga aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc
    52921 gttaccttct aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg
    52981 gttttacaac tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt
    53041 tccaaccgga tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagtgatg
    53101 ctgctaaaaa tggaattgag aatatcttgt acttcttggc aatgatttcc atcaatattg
    53161 ggatttttaa tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc
    53221 tagaagccat ccgccgcaaa ccattgaaac aagaaattga aacctatgtc accttggccg
    53281 gagtggtcat catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct
    53341 tttttagata atcgaggaat attatgaaac aaagtaaaat gcctatccca acgcttcgcg
    53401 aaatgccaag cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc
    53461 gccaagtttc agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag
    53521 ctaaaaacat catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctccag
    53581 cccttcttag tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc
    53641 tttacaaact gaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa
    53701 cctttacagc tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt
    53761 atcaaattca gcccaagtat cgtgatgaaa aacgcccacg taatggactt cttcgtacac
    53821 gtgagtttat catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg
    53881 tttatgatga gtacaaagca gcctatgagc gtattttcac tcgtagtggt ttagacttca
    53941 aggctattat tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca
    54001 ttacatctgc tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat
    54061 ttgacgaaat tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag
    54121 tctctggtga agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa
    54181 tggcaacaaa cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa gttactcgtg
    54241 ttgcaacgcc agatgttaaa tcaattgatg aagttgcagc cttcctcaat gttccagaag
    54301 aacaaacgat taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag
    54361 ttggaaatga ccaactcaac gaagtcaagt tgaaaaacca cttaggagca gatttctttg
    54421 acgttgctag cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac
    54481 cagttggttt gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca
    54541 atgcagttgt cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg
    54601 attttactgc agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg
    54661 gacaaggtgt ccttaacttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa
    54721 ctcgctactc agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa
    54781 tcatcatggg atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac
    54841 acgctcgcct ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca
    54901 atttccctaa agaattggca ccatttgatg tgcatttgat tactgtcaat gtcaaggatg
    54961 aagaagcgca agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag
    55021 tcttgacaga tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg
    55081 gtcttccaat ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga
    55141 tcaaggcaac tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa
    55201 tcctaagcaa gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt
    55261 tttaccttgt tttttctgta taatgggaga aatgagtaga taaagaggta aatgtatgct
    55321 aagatttcca aaggattttg tctggggatc ctctacttct ggaccgcaga cagaaggacg
    55381 tgtagctggt gacggtaagg gagacaatct ctgggattac tggttccaag tggagccaaa
    55441 tcgttactat aatgggattg gttcagataa gacatcgact ttttatgaaa attgggagcg
    55501 ggatattgag cttttgttag agactggtca cacagccttt cggacttcta ttcagtggtc
    55561 acggattttt ccacaaggct gtggaaaagt caacactcaa ggtgtggatt tttatcgtaa
    55621 ggtctttgag gctattaagg ctaaaggaat ttgtctgtta gtcaatctct atcattttga
    55681 tttacctttt gcccttcaag aggatggtga tggttgggaa aataaggcga cagtctcagc
    55741 ctatgaagac tatgctcgtt tttgttttga gacttatgga gatttagtgg atcaatggat
    55801 tacctttaac gagcccatcg ttcctgtaga atttggttat ttttatgatg cccattatcc
    55861 acataaggtg gatgcagagg cagctgttaa ggtagcctat catacacaat tggccagcag
    55921 ccgggctgtt aaggcttgcc atgaactttt gcctgattcc aagattggga ttgtcctcaa
    55981 cttgacaccg gcttatccac gtagccagca tcctgctgat gtcaaggcag ctcgtattgc
    56041 ggcccttttt caggcccaat ctttcttaga tccatctgtc ttggggactt atccacagga
    56101 gttggtagaa atcttgcatg aacacggtct tttacctgat actacagagg aagagttgga
    56161 actcattcgt gataatacgg tggacttcct tggtgtgaac tactatcaac ctttgcgtgt
    56221 tatggctcct cgatttgcta agcatccaga tagtccactc ttaccagaac atttttacga
    56281 gccttatgtg atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga tttatgagca
    56341 agggatttat gacatcgccc aaaatatcaa ggaaaattat ggcaatattg agtggatgtt
    56401 gactgagaat ggtatgggtg ttgaagggga agaaaaattc cgtcaagatg gaatgattca
    56461 agatgattac cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc gtgccattga
    56521 agatggtgcc aactgtaagg gctacttgat ttggaccttt attgactgct ggtcatggct
    56581 caacagctat aaaaatcgct atggtttggt cgaattagac ttggaaacgc aagaacgtcg
    56641 tctgaagaaa tcaggccact ggttcaaaga attaagcgat aataatggat tttaaaaagg
    56701 actctgactg attatcccaa tcggtcagag ttttttgctt acaggagctt aatttgaact
    56761 ataccaattt ttactcttga caagtgaaag aaacaagtat atactgtttt tgctgattct
    56821 ataaaagatg aattagacta taccaatttt aaggagaaag cacagcttgc ctgtgtcgta
    56881 tatactatgt gtggaattgt tggtgttgtt ggaaacacaa atgcaactga tattttgatt
    56941 caagggcttg aaaagcttga ataccgtggc tatgattctg cgggaatttt tgtcctagat
    57001 ggtactgata accatttggt gaaggctgtt ggtcgtatcg cagaattgtc tgctaagaca
    57061 gctggtgttg agggaacaac tggtatcgga catactcgtt gggcaactca tgggaaacca
    57121 acggaagaca atgctcaccc acaccgctct gagacagaac gttttgtctt ggttcacaat
    57181 ggggtgattg aaaactacct tgaaattaaa gaagaatacc ttgctgggca ccacttcaaa
    57241 gggcaaacag atacggaaat cgccgtacat ttgattggaa aatttgcgga agaagacggt
    57301 ctctcagttc ttgaagcctt taaaaaagct cttcatatta tccgtggttc atatgccttt
    57361 gccttgattg actctgaaaa tccagatgtc atctatgtag cgaaaaacaa atctccactt
    57421 ttgattggtc ttggggaagg ctacaatatg gtctgctcag atgctatggc tatgattcgt
    57481 gaaaccaacc aatacatgga aattcatgac caagagttgg taatcgtcaa ggctgatagc
    57541 gtggaagttc aagactatga tggtaacagt cgtgaacgtg ctagctatac tgcggaactt
    57601 gacttgtcag atatcggtaa gggaacttat ccttactaca tgcttaagga aattgatgag
    57661 caaccaactg ttatgcgtaa actcattcaa gcctacacgg atgatgctgg tcaagtagtg
    57721 gttgatcctg ctatcattaa ggctgttcaa gacgcagacc gcatctacat ccttgcagct
    57781 ggaacatctt accatgcagg atttgcttct aagaaaatgt tggaagaatt gacagataca
    57841 ccagttgaac ttggcatctc atctgagtgg ggctacggta tgccacttct cagcaagaaa
    57901 ccactcttca tctttatcag ccaatctggt gaaacagcgg atagtcgtca agttttggtc
    57961 aaggctaatg aaatgggaat tccaagctta acagtgacaa atgttccagg ctcaaccctc
    58021 tcacgtgaag ccaactatac catgctcctt cacgcaggtc ctgaaattgc cgtggcatca
    58081 actaaagcct atacagcgca aatcgcagcc cttgccttcc ttgcaaaagc agtcggagaa
    58141 gcaaatggta atgctaaagc gcaagccttt gacctgattc atgaattgtc aatcgtagct
    58201 cagtctatcg aatcaactct ttcagagaaa gaaaccattg aagccaaggt tcgtgaactt
    58261 cttgaaacaa ctcgtaacgc cttttacatc ggacgtggtc aagattacta cgtagccatg
    58321 gaagcaagtc tcaaactcaa agagatttct tatatccagt gtgaaggctt tgctgcagga
    58381 gaactcaagc acggaaccat tgccttgatt gaagaaggaa cgcctgtttt ggctctcttg
    58441 tcagatccag ttcttgccaa tcatactcgt ggaaatatcc aagaggtcgc agcccgtggt
    58501 gccaaagtcc tcactatcgc agaagagaat gtagccaaag ataccgacga tatcgtcctt
    58561 acgaccgtac atccatacct ctcaccaatt tcaatggtcg taccaacgca attagtcgct
    58621 tactttgcaa ccctccaccg tggcctcgat gtggacaaac cacgtaacct tgccaagtca
    58681 gtaacggtag aataagctaa aaaagtctag ttatctaggc tttttcttgt gagcaaattg
    58741 gttgcttgta ctcaagattc gtgttagaat aatttttcaa attgaaggac agagatagac
    58801 aaggagaatc acaatggtag aattgggaat ttcaacattt ggggaaataa cggagcttga
    58861 agggactgga caaacttaca gtcatgctga acgcattcgc cagttggtgg cagagattga
    58921 gctggctgac aaggttggtt tggacgtata tgggattggc gagcaccatc gggcggattt
    58981 tgcagtatca gccccagaga ttgtcctggc cgctggggca gtcaatacca agaaaatccg
    59041 tttgaccagt gcagtcagca ttctgtcaag catggacccg attcgtttgt tccaacagta
    59101 tgccactatc gatgctttgt caaatggacg atcggagatt atggctggaa ggggctcttt
    59161 cacggaatct ttccctctgt ttggttatga cttgaaagac tacgactctc tttttgatga
    59221 gaaattagac ttgcttcagt tagtcaatga aaagaccaag ttagactggc aaggtcgatt
    59281 gactcaaacg attgctggta aagaagttta tcctcgtcca gttcaggaca aattgccctt
    59341 gtggatagct acaggtggtc atgtcgaatc aacagtgaag attgctcagg ctggtctacc
    59401 gattgtatat gctattattg gtggtaatcc acgttatttt aaaaagttga ttcaggctta
    59461 tcgtgagatt ggaagcgaag cgggccatgc tgacaaagac ttgaaagtgg gagcccattc
    59521 ttgggggtgg attgcggaag atggtgagca ggcggtgaaa gattatttcc atccgactaa
    59581 gcaagtggtg gatgctattt ccaaagaccg tccgcactgg caggaattgc gttatgagca
    59641 atatttggag caggtagggt caaatggcgc catgtttgtt ggcaatccag atcaggtggc
    59701 cgaaaaattg attcgcatga tagaggattt aggattggac cgcttcatgc ttcatctacc
    59761 gcttggttct atgcctcatg accaggttct gagagctatt gaactcttcg gaacacaagt
    59821 tgcacccaaa gtacgagctt attttgctat gaaagaggct taataaaaaa tcctaatcaa
    59881 gtttattagg acaacaaata ttgtacgaaa attaatcccc cgagctataa tgcttggggg
    59941 atttttctat aggagggcta gcttagttct cttttttatt ttttagtaag aaaccgagac
    60001 caaggagcgc aaggaggctg attcctgcaa ataggagttt gttttcgttt ttgattcctg
    60061 tatttggaag ttcagcttgt ctatctgggg ttgcagatat attttccttg ctagagtttt
    60121 ctaccgattc ttttcgaacc gcttctttta cagatgatgc ttgtgcttct tgtgctggtt
    60181 gttcagcttg tgaatcagct gtagcttggc taggtttatt ttccgcatca gctactttgg
    60241 catctggttt agtagaatca ggtctagctt ctggagctgg gtcttgatgt gcagggtgag
    60301 aagcttcatt ttgatgttca ggcttggaag gggttgagtc tggtttctct tctgcagttg
    60361 actcatggct agttccattt tgagagactc gaagaacagt agctgtaagg gcattcaatt
    60421 ttaagccttt ttcagtccat tcaagtcctt tcgggttggc aattccgact gatcctgctt
    60481 ggttttcatc tgccaaaact tccgcatttc ttagatgtgc aaaggcagtt cccaaattaa
    60541 attcgcgagc tttttcatcc gcattgacaa agactgcgta gatatcgccg tttggagcag
    60601 tgatttggta gccaatcact acatcctctt tttccacacc attttggcct gggacagtga
    60661 tgaggtggac acggtctttg atatcttgga gactcttaag tcggaaggca tctgtagatt
    60721 gacgaagggc aatcaaacct ttcatatagt cacggctctt gacattttca ggataagctt
    60781 taccatctgt agccttagtc cagtcaaact tgttgactgc gtcgctagaa tcgtaagaat
    60841 catggatgaa gtaaggatag tcaaatgggt tgccgtcctt atcacgcaac aagtgagatt
    60901 tgtttggaac cttatcctct gctactggag tcttgtaggc tgggtcacgg aattgtttag
    60961 tacgtccata ttcctgaccg gagtggataa atggagttcc ttgagctgtc aagaccatga
    61021 gatttccaag tcgtaaacga cggtggattt cagcatagtt ctcagccttg cttgggtctt
    61081 ttttgataga ctgggcaatg atgtcaaaga gggtcaagtt atcatgggct gcgatgtatt
    61141 ggatgacatc tccagggctg tcagcttcaa agttagttgg ttgagcaatg agatttttaa
    61201 agatggtgtt gacatcacgc ttgccacctg tgataaaggc aggttgacct tcgtttggat
    61261 aaccagattt gaggttgtta cggatgtcat ctgaaaagac agcgacagta tcggtatgtt
    61321 tcatccaatc ttggtcagca gctttagtag gcatgttttc atcaccggca taggttctcc
    61381 aaccttcgcc taacatgatt agatttggat tgagggcgcg tgcagccttg taagcttctt
    61441 cgatagaagc ggcgtcatgg tctcccatca tatcgaagcg gaagccatcc actttgtagg
    61501 tatcaactag gtatttgata gagtcaacta ggaggcgttt ggtcatatgg tgggttgtcc
    61561 ccaagcgtcc accaccaaag ctagttcgag gtgtgccatc ggcatccata aagtggtagt
    61621 agtttggctc taggtcttca aagatatcga ctttggctgt gtggttataa acgacatcta
    61681 ggatagctcc cataccacgt ttgtggattt cgttgatgag gtttttaaat tctgcgattc
    61741 gtttttctgg attcttagga tcgcttgagt acataccagt caaggagaag tagttttgag
    61801 ggtcatatcc ccagttgtag ttgctgttgc ttgaagcata gtcagacaag cgttcatggt
    61861 ttttcaattc attgacaaag tagtaagaca agactggaag gagctggata tgggttacac
    61921 ccaagtcttt gagatagtct agtttttcaa tgaaggcttc aaaagtccca aatggtttgg
    61981 tcaagtcttt tgcaatggca ggatctgaag tgaagtcacg cacatgagct tcgtagataa
    62041 cggcgtcttc acgagtcttg aaattgtgaa tcttaccata agtcaagtct tgaggtccga
    62101 gtttagctgg atctacaaag gcggctttag ccactttatg ggcatcgtca atcttggcat
    62161 cgttgctatt ccaagcagca agagatttag cgtaaggatc gagtgcaaga acagttttac
    62221 cttgacgctc gatttggtat tgataatagt agccagtgaa atctgtgatt ccgagtttgt
    62281 ttgtgctgtc tagagtttgt ttccaagttc ctctttcccc tttttcgaga gcgacagttc
    62341 caactacttt gtcagggtca ttcttgtcgt agacaacaac agaaacctta tcagcacttg
    62401 gtgaccaaag ggtcaaatca acttgttttc cttcttcttt taggtcagct cctagtttgc
    62461 catcatagct gtatgtctca tctttcaggc gccagcttgt tttggtagtg aattggtcgg
    62521 aattgtagct aacagtataa ggatgttttg tgtcagagaa atctccgctg taggtcactt
    62581 tcttaccagc ttcatcgatt gcaacatcgg taatagttac cttgtttcct aggtgattag
    62641 tgatgttgga gtgtttgagg atatcttctt ttttagcacc gacaagtgtt gaaaagctac
    62701 tttcaatgct agaagtgcct acgtgttggg ctcctgtcat acggatatca tggacatagt
    62761 atggatttgt gtaaatcgat tcatcatcgt cttttaggaa aatttggcta tgatttttca
    62821 aatctgtgaa cttataattt tctttacgga ttttcacgtc gtctccttgt ttgctctcat
    62881 ctagtaataa aaatccaaat tctcttgcgg cttcattaag aggaatgtcg atatagcggc
    62941 catatttgct tgtagccgta aagtctgttc cgtcaggcca ttgagcgcta cttggatttt
    63001 ttacatctcc ccagtaccag agagatttct tgtcatagtt gccatctgtg cggtagtagt
    63061 tgacgcgaac agttcctgca ggctgtggct cgtaagagaa aaccttgtaa tcttggtcta
    63121 accaagcctc gttcattttt ggaactagtt tttctacaga tttatcgccg gttagatttt
    63181 ttccagctgt attgttgatg aggaagctaa ttttcttggc ttgttctccc tttaatttga
    63241 catctaggta atagccgtag tcatctttct tggcatcctt gaaggacaaa gctccgtttg
    63301 gccagttttc agatggtttt tcaacatcgt cccaagtcca tagtccttga gcatccttgt
    63361 tttcttcagg aagttttttg acatggatac ggaagtagtt atcttcgatg ggctcttctg
    63421 ccttagtttc agttgttact ggactagtag aagtagttgg ctctgttgca ggtttttctt
    63481 ctgttttctc tagggaagcg tttgcatttc taggtgaaga aatatcactt tcgttcttac
    63541 cagagccagc tgctgtatca gtaagaggtt gggcaagggt ggttgtattt ctgttgttgg
    63601 gttcgttagt ggttggtgta ctttcgtcgg atgagatagt tggtgtagcc atggcaagca
    63661 agacaaggct tgcgccgata aggacagaac cagtcccatt tttgagggaa cggatgctgt
    63721 agaccatttt tttctcagtg tgagatggtg tttttctcat aatgattctc caatcaataa
    63781 atttctatat cagtatagca tgtagtaaaa caatatgcaa gcgttttctt tgatttgtga
    63841 aaaaaattct tacttttgag aagttttctg tactatttta tatatcagta taaatgacgg
    63901 agataaaaat gtcacataag ccaagccgta ttattaggaa gatgatgtgt tcccagctat
    63961 ttttattcag aaattgatct ctaacattac caataaaaaa gaaaaatatc ttgacaaaca
    64021 agggaaaatt ttgttacaat aatagacggt actttttact tttggtctct caagagtgta
    64081 cagggacgtg ctgacaaatg ttgcaaaagt acacacagat gatatctgtc accaagtgta
    64141 tcatcaccaa aaataaaaaa acacaggaga atgtagatgc ctacaattaa ccaattggtt
    64201 cgcaaaccgc gtaaatcaaa agtagaaaaa tctaaatcac cagctttgaa cgttggttac
    64261 aatagtcata aaaaagttca aacaaacgtt tcttcaccac aaaaacgtgg tgttgcaact
    64321 cgtgttggaa caatgacacc taaaaaacct aactcagccc ttcgtaaatt cgctcgtgta
    64381 cgtttgagca accttatcga agttactgcc tacatcccag gtatcggaca caacttgcaa
    64441 gagcacagcg tggtgcttct tcgcggtgga cgtgtaaaag accttccagg ggtacgttac
    64501 catatcgtcc gtggtgcact tgatactgca ggtgttaacg atcgtaaaca aggtcgttct
    64561 aaatacggta ctaaacgtcc aaaagcataa ggaaagggga taaagagaaa tgagtcgtaa
    64621 aaatagagct ccaaaacgtg acgtattgcc agatccgcta tacaattcac aactagttac
    64681 tcgtcttatc aaccgcgtta tgcttgatgg taaacgtggt actgctgctt caatcgttta
    64741 cggtgctttt gagcaaatca aagaagctac tggcaacgat gcacttgaag tatttgaaac
    64801 agctatggaa aacatcatgc ctgtacttga agtacgtgca cgtcgtgttg gtggttctaa
    64861 ctaccaagtc ccagttgaag ttcgtccaga acgtcgtaca acacttggac ttcgttggtt
    64921 ggtaacaatc gctcgtcttc gtggtgaaca cacaatgcaa gaccgtcttg caaaagaaat
    64981 cttggatgct gctaacaaca ctggtgcagc agttaagaaa cgtgaagata ctcaccgtat
    65041 ggctgaagct aaccgtgcat tcgcacactt ccgttggtaa gataggatgc gaaagcgtta
    65101 agaaagttcc agagaaaata gggaatcgaa gcaggttgcg gttgcaacca atgagattca
    65161 tctttttctc cagactttta gcttgagctc aactaaatca tgatgttagg aacggtaagg
    65221 atgcaaggtg aaaataggaa actgacgcag tattcgacga atacaaggag ttttatcttt
    65281 ttcacgcagc atcccgttcc agctcacatc ggctaactaa ctttagcccg ggttcaaatt
    65341 agctaaatcg attagtatta gctataactc agcttaccat ctcgtaagtt gaaaccaaca
    65401 atagcatgaa aacattgaga acgggtaggt cctgcctatc cgtttttatt aaaatcgtgt
    65461 tataatagaa tagaaatcaa aaataaatag gagaaacaaa cctcatggca cgcgaatttt
    65521 cacttgaaaa aactcgtaat atcggtatca tggctcacgt cgatgccggt aaaacaacaa
    65581 ctactgagcg tattctttac tacactggta aaatccacaa aatcggtgaa actcacgaag
    65641 gtgcgtcaca aatggactgg atggagcaag agcaagaacg tggtatcacg atcacatctg
    65701 ctgcgacaac agctcaatgg aacaaccacc gcgtaaacat catcgacaca ccaggacacg
    65761 tggacttcac aatcgaagta caacgttctc ttcgtgtatt ggatggtgcg gttaccgttc
    65821 ttgactcaca atcaggtgtt gagcctcaaa ctgaaacagt ttggcgtcaa gcaactgagt
    65881 acggagttcc acgtatcgta tttgccaaca aaatggacaa aatcggtgct gacttccttt
    65941 actctgtaag cacacttcac gatcgtcttc aagcaaatgc acacccaatc caattgccaa
    66001 tcggttctga agatgacttc cgtggtatca ttgacttgat caagatgaaa gctgaaatct
    66061 atactaacga ccttggtacg gatatccttg aagaagacat cccagctgaa taccttgacc
    66121 aagctcaaga ataccgtgaa aaattgattg aagcagttgc tgaaactgac gaagaattga
    66181 tgatgaaata cctcgaaggt gaagaaatca ctaacgaaga attgaaagct ggtatccgta
    66241 aagcgactat caacgttgaa ttcttcccag tattgtgtgg ttcagccttc aaaaacaaag
    66301 gtgttcaatt gatgcttgat gcggttatcg actaccttcc aagcccactt gacatcccag
    66361 caatcaaagg tattaaccca gatacagacg ctgaagaaat tcgtccagca tctgacgaag
    66421 agccatttgc agctcttgcc ttcaagatca tgactgaccc attcgtaggt cgtttgacat
    66481 tcttccgtgt ttactcaggt gttcttcaat caggttcata cgtattgaat acttctaaag
    66541 gtaaacgtga acgtatcgga cgtatccttc aaatgcacgc taacagccgt caagaaatcg
    66601 acactgttta ctcaggtgat atcgctgctg ccgttggttt gaaagatact acaactggtg
    66661 actcattgac agatgaaaaa gctaaaatca tccttgagtc aatcaacgtt ccagaaccag
    66721 ttatccaatt gatggttgag ccaaaatcta aagctgacca agacaagatg ggtatcgccc
    66781 ttcaaaaatt ggctgaagaa gatccaacat tccgcgttga aacaaacgtt gaaactggtg
    66841 aaacagttat ctcaggtatg ggtgaacttc accttgacgt ccttgttgat cgtatgcgtc
    66901 gtgagttcaa agttgaagcg aacgtaggtg ctcctcaagt atcttaccgt gaaacattcc
    66961 gcgcttctac tcaagcacgt ggattcttca aacgtcagtc tggtggtaaa ggtcaattcg
    67021 gtgatgtatg gattgaattt actccaaacg aagaaggtaa aggattcgaa ttcgaaaacg
    67081 caatcgtcgg tggtgtggtt cctcgtgaat ttatcccagc ggttgaaaaa ggtttggtag
    67141 aatctatggc taacggtgtt cttgcaggtt acccaatggt tgacgttaaa gctaagcttt
    67201 atgatggttc atatcacgat gtcgactcat ctgaaactgc cttcaagatt gcggcttcac
    67261 tttcccttaa agaagctgct aaatcagcac aaccagctat ccttgaacca atgatgcttg
    67321 taacaatcac tgttccagaa gaaaaccttg gtgatgttat gggtcacgta actgctcgtc
    67381 gtggacgtgt agatggtatg gaagcacacg gtaacagcca aatcgttcgt gcttacgttc
    67441 cacttgctga aatgttcggt tacgcaacag ttcttcgttc tgcatctcaa ggacgtggta
    67501 cattcatgat ggtatttgac cactacgaag atgtacctaa gtcagtacaa gaagaaatta
    67561 ttaagaaaaa taaaggtgaa gactaatccg tcctcactct agaaggaagt cacttagtgg
    67621 cttccttttg tctttagaaa atacctctaa atatggtaaa atagtagaag aataatgtga
    67681 ggaaaatgaa tgtcaaatag ttttgaaatt ttgatgaatc aattggggat gcctgctgaa
    67741 atgagacagg ctcctgcttt agcacaggct aatattgagc gagttgtggt tcataaaatt
    67801 agtaaggtat gggagtttca tttcgtattt tctaatattt taccgattga aatcttttta
    67861 gaattaaaga aaggtttgag cgaagaattt tctaagacag gcaataaagc tgtttttgaa
    67921 attaaggctc ggtctcaaga attttcaaat cagctcttgc agtcctacta tagggaggct
    67981 ttctctgaag gtccatgtgc tagtcaaggt tttaagtccc tttatcaaaa tttgcaagtt
    68041 cgtgctgagg gcaatcagct atttattgaa ggatctgaag cgattgataa ggaacatttt
    68101 aagaagaatc atcttcctaa tttagccaaa caacttgaaa agtttggttt tccaactttt
    68161 aactgtcaag tagagaagaa tgatgtcctg acccaagagc aggaagaggc ctttcatgct
    68221 gaaaatgagc agattgttca agctgccaat gaggaagcgc tccgtgctat ggaacaactg
    68281 gagcagatgg cacctcctcc agcggaagag aaaccagtct ttgattttca agcgaaaaaa
    68341 gctgcagcta aacccaagct ggataaggcg gagattactc ctatgatcga agtgacgaca
    68401 gaggaaaatc gtctggtctt tgaaggggtt gtttttgatg tggagcaaaa agtgactaga
    68461 acaggtcgtg ttttaatcaa ctttaaaatg acggactaca cttcaagttt ttctatgcaa
    68521 aagtgggtta aaaacgagga agaggcccag aagtttgacc tcatcaagaa gaattcttgg
    68581 ctccgagttc gagggaatgt ggagatgaat aacttcacac gcgatttgac tatgaacgta
    68641 caggatgtgc aggaagttgt tcactatgag cggaaggatt tgatgccaga aggtgagcgt
    68701 cgggttgagt ttcatgctca tactaacatg tcgactatgg atgctttgcc agaggtcgaa
    68761 gagattgttg caacagctgc taagtgggga cacaaggcgg ttgctattac ggaccatggg
    68821 aatgtccagt cctttccaca tggctataag gcggctaaga aagcgggaat ccagctgatc
    68881 tatgggatgg aagccaatat cgtggaggac cgtgtcccta tcgtctataa cgaagtggag
    68941 atggacttgt cagaagcaac ctacgtggtc tttgacgtgg aaacgacggg actttcagct
    69001 atctataatg acttgattca ggttgcggcc tctaagatgt acaaggggaa tgttattgct
    69061 gaatttgatg aatttatcaa tcctgggcat cccttgtcag cctttactac agagttaact
    69121 ggaattacag atgatcatgt caaaaatgcc aaaccactag aacaagtttt gcaagaattc
    69181 caagaatttt gcaaggatac ggtcctagtt gcccacaatg ctacctttga cgttggcttt
    69241 atgaatgcta attatgagcg tcatggtctt ccaaagatta gtcagccagt tattgatacg
    69301 ctggagtttg ctagaaacct ctatcctgag tataaacgcc atggtttggg gcctttgacc
    69361 aagcgttttg gtgtggcctt ggaacatcac cacatggcca actacgatgc ggaagcgact
    69421 ggtcgtctgc ttttcatctt tatcaaagag gtagcagaaa aacatggtgt gaccgattta
    69481 gctagactca acattgatct aatcagtcca gattcttaca aaaaagctcg gatcaagcat
    69541 gcgaccatct atgtcaagaa tcaggtaggt ctaaaaaata tctttaagct ggtttccttg
    69601 tctaatacca agtattttga aggagtgcca cggattccga gaacggttct agatgcccat
    69661 cgagagggct tgattttagg ttcagcctgt tcagagggtg aagtttttga cgtggtcgtt
    69721 tctcaaggtg tggatgcggc ggttgaggtg gccaagtatt atgactttat cgaggtcatg
    69781 ccaccggcta tctatgcgcc cttgattgcc aaagagcagg tcaaggatat ggaggaactc
    69841 cagaccatta tcaagagttt gatagaggtt ggagatcgcc ttggcaagcc tgttctggct
    69901 acgggaaatg ttcactatat cgaaccggaa gaagagattt atcgtgaaat tatcgtccgt
    69961 agtttgggac agggtgcgat gattaaccga actatcggtc atggtgaaca tgcccaacca
    70021 gcgccacttc caaaggctca ttttcgaacg actaatgaga tgttggatga atttgccttt
    70081 ttgggagagg aactggctcg taaactggtt attgaaaaca ctaatgcctt ggcagaaata
    70141 tttgaacccg ttgaagtcgt taagggtgac ttgtatacgc ctttcatcga caaggctgaa
    70201 gaaacagttg ctgagttgac ctataagaaa gcttttgaga tttatggaaa tccgctgcca
    70261 gatattgttg atttgcggat tgaaaaagaa ttaacatcca tactggggaa tggatttgct
    70321 gtgatttatc tggcatcgca gatgctggtg caacgttcta atgaacgggg ttatttggtt
    70381 ggttctcgtg ggtctgtcgg atctagtttc gttgcgacca tgattgggat tacggaggtc
    70441 aatcctctct ctcctcacta tgtctgtggt cagtgtcagt acagtgagtt tatcacagat
    70501 ggttcgtacg gttcaggatt tgatatgccc cataaggact gtccaaactg tggtcacaaa
    70561 ctcagtaaaa acggacagga tattccgttt gagaccttcc ttggttttga tggggataag
    70621 gttcctgata ttgacttgaa cttctcggga gaagatcagc ctagcgccca cttggatgtg
    70681 cgtgatatct ttggtgaaga atatgccttc cgtgcgggaa cggttggtac ggtagctgcc
    70741 aagactgcct atggatttgt caagggttac gagcgagatt atggcaagtt ttatcgtgat
    70801 gcagaagtag aacgcctcgc tcaaggagcg gcgggtgtca agcggacaac aggccaacac
    70861 ccggggggaa tcgttgttat tccgaactac atggatgtct acgattttac gcctgtccag
    70921 tatccagcag atgatgtcac ggctgaatgg cagaccactc actttaactt ccacgatatc
    70981 gatgagaacg tcctcaaact cgatgtactg ggacatgatg atccgaccat gattcgaaaa
    71041 cttcaggatt tgtctggtat tgaccctaat aaaattccta tggatgacga aggcgtgatg
    71101 gcactctttt ctgggactga tgtgctaggg gtaacacctg aacaaattgg aacgcctacg
    71161 ggtatgttgg ggattccaga gtttggaaca aatttcgtac gtggaatggt agacgaaacc
    71221 catccgacaa cctttgcgga attgcttcag ctgtctggtc tgtcccacgg tactgacgtt
    71281 tggttgggga atgctcagga tctgattaag caaggaatag cggacctatc gactgttatc
    71341 ggttgtcggg acgacatcat ggtttacctc atgcatgcgg gtctggaacc taagatggcc
    71401 tttaccatta tggaacgggt acgtaagggt ttgtggctaa agatttcaga agaggagaga
    71461 aatgactata tcgaagccat gaaggctaat aaggtgccag agtggtatat cgaatcctgt
    71521 gggaaaatta agtacatgtt ccctaaggcc catgcggcag cctacgttat gatggccttg
    71581 cgtgtagctt acttcaaggt tcaccatcct atttattact actgtgctta cttctccatt
    71641 cgtgctaagg cttttgatat caagaccatg ggtgcgggct tggaggtcat caagcgcaga
    71701 atggaagaaa tctctgaaaa acggaagaac aatgaagcct ctaatgtgga aatcgatctc
    71761 tatacaactc ttgagattgt caatgagatg tgggaacgag gtttcaagtt tggtaaatta
    71821 gatctctact gtagtcagac gacagagttc ctcatcgacg gggataccct tatcccacca
    71881 tttgtagcaa tggatggtct gggggagaac gttgccaagc aactggtgcg ggcgcgtgaa
    71941 gagggagaat tcctctctaa aacagaacta cgcaagcgtg gtggactctc atcaaccttg
    72001 gttgaaaaga tggatgagat gggtattctt ggaaatatgc cagaggataa ccagttgagt
    72061 ttgtttgatg agttgtttta aaaaattgct taataatcta ttaaaagagg ctaacgtata
    72121 tccaatagat ttacattagc tttctttttt gttaaaatag tctatggaaa gagggtgaga
    72181 gtatgtcaaa gatgagtata agcatccgtc tggatagtga ggttaaggag caggcccaac
    72241 aggtgtttag taatctggga atggatatga caacagctat taatattttc cttcgtcagg
    72301 caattcaata tcagggatta ccttttgatg ttagactaga cgaaaatcgg aagttgctcc
    72361 aagcgttaac ggatttagac caaaatcgta atatgagcca gtcttttgaa tcagtctcag
    72421 atttgatgga ggacttacgt gcttaagatt cgttatcata aacagtttaa aaaagatttt
    72481 aagttggcta tgaagcgtgg tttgaaggca gaattattag aagaagtttt gaattttctg
    72541 gttcaagaaa aagaacatcc tgccagatat cgtgatcatt cattgacggc atccaagcat
    72601 tttcaaggag tttgtgaatg ccatacccag ccagattggc ttttggttta taaagtagac
    72661 aagtcggaat tgattttaaa tttgctgagg acaggcagtc acagtgattt attttaatct
    72721 attttaaggg ggttctcatg aaactaagaa tatttgcgga agataagccg gctaagaagg
    72781 tatttgaata tcaattagaa cttgctgatc gtacaattct tctatcgaca gcactcttgt
    72841 caggtgctat tgctttagca ggaatctttt ctgctttgag agaaaaataa aaatagaaaa
    72901 gagaaaacag aatggtttta ccaaatttta aagaaaatct agaaaaatat gcgaaattgt
    72961 tggttgcgaa cggaattaac gtgcaacctg gtcacacttt ggctctctct attgatgtgg
    73021 agcaacgtga attggcacat ctaatcgtga aagaagctta tgccttgggt gcgcatgagg
    73081 tcatcgttca gtggacagat gatgtgatta accgtgagaa attcctccat gccccgatgg
    73141 agcgtttgga caatgtgcca gaatacaaga ttgctgagat gaactatctc ttggagaaca
    73201 aggctagccg tcttggagtt cgttcatctg atccaggtgc cttgaacgga gtggacgctg
    73261 acaagctttc agcttctgct aaagctatgg gacttgccat gaagccaatg cgaatcgcaa
    73321 ctcaatctaa caaggttagc tggactgtag cagccgctgc tggacttgaa tgggctaaga
    73381 aagtcttccc aaatgctacg agcgatgaag aagcagtcga tctcctttgg gaccaaattt
    73441 tcaaaacttg ccgtgtctac gaagcagatc ctgttaaggc ctgggaagag catgcagcta
    73501 tcttgaagag caaggccgat atgcttaata aggagcaatt ttcagccctt cactacacag
    73561 cgccaggaac agatttaaca cttggtttgc caaagaacca cgtttgggaa tcagctggtg
    73621 ctgtcaatgc acagggcgaa ggattcttgc caaatatgcc gacagaagag gtcttcacag
    73681 cgcctgactt ccgtcgtgca gatggttatg tcacttctac aaaaccgctt agctacaacg
    73741 gaaatatcat cgaaggtatt aaggtaacct ttaaggatgg acaaatcgta gatatcactg
    73801 ctgagaaggg tgatcaggtt atgaaagacc ttgtctttga aaatgcgggt gcgcgtgcct
    73861 tgggtgaatg tgccttggta ccagatccaa gtccaatttc tcagtcaggc attaccttct
    73921 ttaacaccct tttcgatgaa aatgcgtcaa accacttggc tatcggtgca gcctatgcga
    73981 ctagcgttgt tgatggagcg gagatgagcg aagaggagct tgaagctgca gggcttaacc
    74041 gttcagatgt tcacgtagac tttatgattg gttctaacca aatggatatc gatggtattc
    74101 gtgaggatgg aacgcgagta cttcttttcc gtaatgggaa ttgggcaaat taaggagata
    74161 atatgttagg aagtatgttc gttggtctcc tagtgggatt tttagcaggt gctatgacca
    74221 atcgtggaga gcgaatggga tgttttggaa aaatgtttct cggttggatc ggagcctttc
    74281 taggtcactt gctctttgga acttgggggc cagttttatc aggaacagct attatcccag
    74341 ctgttttagg tgccatgatt gtcttagcta ttttttggag acgaggaagt taatttccta
    74401 aatctgatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctcaaa
    74461 gcactgcttt gaggttgcag atagaactga cgaagtcagt aacatatata cggcaaggcg
    74521 acgttgacgc ggtttgaaga gatttttgaa gagtatgaaa cgaaaaggag gttggtcatt
    74581 gtaccagcct ccttttgata tgatataata gttctatgag attagataaa tttttagttg
    74641 cctgtgcggt gggaagtcgg actgaggtca aaaacttgct caaggctggg cgcgtgactg
    74701 taaatggtaa aaaagaaaaa tcagctaaat tgcagattga tgaaaaaata gatgagattc
    74761 gctttgatgg gcaagtgttg gagtatgaag agtttgtcta ctacatgatg aacaagccca
    74821 aaggagttat ctcagcgact gaggatccca agcacagaac cgttctggac ttgttggatg
    74881 acttggcgcg gagtaaggaa gttttcccag taggacgctt ggatattgac acgcatggtc
    74941 ttttgctctt gaccaataat ggtcagctgg ctcatgttct tctttcgccc aagcgtcatg
    75001 tggacaagac ttatcaggct caggtcaagg gaattatgac ccaagaagat gtggagacat
    75061 ttatcaaggg cattccgctc aaagacttta cctgtcagcc cgctagactg gagattcttt
    75121 ccacagatgc agaaaagaat cagagccaaa tccgtgtgac cattgcagaa gggaagtttc
    75181 atcagatcaa gcgtatggtg ggctactgtg gcaaggaagt ggtggacttg caacgattga
    75241 ctatgggaac tttagtatta gatgagaacc tggaacgagg ggaatggcgt cgcttgacca
    75301 aggaagaatt agaaattctc cgcgctaata ttatttaatt tagtttaata ctcaatgaaa
    75361 atcaaagagc aaactaggaa actagccgca ggctgtactt gagtacggca aggcgacgtt
    75421 gacgtggttt gaatttgatt ttcgaagagt ataaattcga aaaaggtgag ggacaatgtc
    75481 ctcgcctttt atgtttttta gttgcttcct ttgtgaaaag agttataata gactgtagaa
    75541 taaaaggagg aatctatgaa cgcgattcaa gaatcattta ctgataaact atttgccaac
    75601 tatgaagcaa atgtaaaata ccaagcgatt gaaaatgctg ccagccacaa cggaattttt
    75661 gcagctctgg aatgtcgcca aagccatgta gacaacacac ctgttttctc attggattta
    75721 accaaggaca aggtcactaa ccagaaagcg tctggtcgtt gctggatgtt tgcggctctc
    75781 aacaccttcc gccacaaact catctcgcaa tacaaattgg agaactttga gttgtcacaa
    75841 gcccacactt tcttctggga taagtatgag aaatcaaact ggttcttgga gcaagtcatt
    75901 gcgacttcag accaagaatt gactagccgc aaggttagct tcttactcca aacacctcaa
    75961 caagatggcg gtcaatggga tatggtcgtt tccctctttg aaaaatacgg tgtcgtgcct
    76021 aagtcagttt atcctgagtc tgtttcatct agcagcagtc gtgagctaaa tgcgatcctt
    76081 aataaattgc ttcgtcaaga tgctcaaatc ttgcgtgatt tgcttgtttc tggtgcagat
    76141 caagcgactg ttcaagctaa gaaagaagac ctcttgcaag aaatctttaa ctttcttgct
    76201 atgtcattag gacttccacc acgcaagttt gactttgctt atcgcgataa agataacaac
    76261 tataaaagtg aaaaaggaat cacaccacaa gagttttaca agaaatatgt caatcttcct
    76321 ttagaagact acgtttctgt tatcaatgct ccaactgctg ataaacctta cggaaaatct
    76381 tacacagttg agatgttggg gaatgtggtt ggtagccgtg cagttcgcta catcaacgtt
    76441 ccaatggagc gcttgaaaga attggcgatt gcccaaatgc aagcaggtga gactgtttgg
    76501 tttggttctg atgtcggcca gctcagcaac cgtaaggctg gcatccttgc gacagatgtt
    76561 tatgactttg aatcaagcat ggacattaaa cttactcaag acaaggctgg acgtttggac
    76621 tatagcgaaa gcttgatgac ccacgccatg gtcttgacag gtgttgactt ggacgaaaat
    76681 ggtaaatcaa ccaagtggaa ggttgaaaac tcatggggag acaaggtcgg tacagatggt
    76741 tactttgttg cctcagacgc ttggatggac gaatacacat accaaatcgt tgttcgtaag
    76801 gaattgctga cagcagaaga acaagctgcc tatggagcag aaacaatcgt acttacacca
    76861 tgggatccaa tgggagcctt ggctgaataa aagcatagaa aaaaggaatc agattttaga
    76921 acctggttcc tttttagttg cttgattaca tgatgtgaag aacatgtgcc acaataccca
    76981 ctgcgaagag ggcaaggata atagtgattg gagatacttt tttcttaagt aagtacatgc
    77041 aaagtaaagt aaggagtagt cctgataatc caggaatcaa catatccaag ttttgttgga
    77101 aagtagtaac tttttcagga gtttgagaca atccttgtcc tacttgtgcg aatgcttctt
    77161 ggataccttt agacccttct ggcaatttat cccaatggat ataagccttt tcatctagtt
    77221 gaactttaga aacatcgaaa gcaaatttaa tatttaccca gcgttgaaca aggacagcaa
    77281 gaatgaacat cccaaggata gaagctcctt tagtgatatc ttgaaggata ccaccagaca
    77341 tatctttagt gatttctgat ccagccttgt atccaatctc ttgaacatac cacaagaatg
    77401 acatacgaat caagttccat gcaacaaaga agaggagtgg acccaagata ttgccagtaa
    77461 gggcaagtga agcaccgaga gatccaagga ttgggcgcac tgtaaaccag aatactgggt
    77521 caccgatacc agcaagaggt cccatcatac cgattttaac cccttggata gcagcgtcat
    77581 cgatttccac accgttagca cgttcttctt caagcgcaag agtaaccccc atgactggag
    77641 cagctacgta tggatgagtg ttgaagaact caaggtgacg ctcaagagca gcgatttgat
    77701 cttctttttt agtatagagt tttttgatag ctggaatgag tgtataagcc cagcccaagt
    77761 tttgcatccg ttcaaagttc caagaccctt gtaagaaggt tgaacgccac caaacttttt
    77821 tacgatctga tttagttaat tgaagttttt cagtcatgat gttttcagtc ctttcttatc
    77881 ttagtagtct tctaggatat cgccgattgg gtcgttagaa gttgcggctc ctccgccacc
    77941 atttccacca gttttagaaa ggtgaaggta gataagagcg atagcaacac cgatagcacc
    78001 gaatccgatt agagtaatat ctgacacagc agcgagaacg aaaccaagag cgaagaatgg
    78061 ccatacttca cgagttgcca tcatgttgat aaccatggcg taaccaacgg caacgaccat
    78121 accaccaccg atagccatac catctttgag ccagtctggc atggcactaa ggatactttg
    78181 tacagtttca gttggtacca taaggagaag agctgcagga agcgcgatac gaagtccttg
    78241 gaaaagtagc gcaatgaaat gcgcacgctc cacagcgccg aagtcacctt ttttagcggc
    78301 agcatctgca gtatgaacca aaccaactga aattgtacga acaatcattg tcaagaaaag
    78361 tccagctacg gcaagaggga tagcaaccgc ttgggcaaca ccgataccag tcttggtaaa
    78421 gtcaccacca agaaccatga taatggcagc agcgacagaa gcaagtgcag catcaggagc
    78481 gatagcagca ccgatatttg accaaccaag ggcaatcatt tgaagcgatc caccgaggat
    78541 aatccctgct tccaagtgac ctgttacaag cccaataagg gtacaggcta caagtggttg
    78601 gtgaaattgg aactggtcga ggatgccttc aagacctgca aagaaggcta caacgactac
    78661 taaaaccata gaaataatag acatgtttaa aatcctttca taaataatgg cttatttgac
    78721 attggctttg ttaatcaagt caaacaaatc ttttttagaa tcatttggta ctttacggac
    78781 atcaaattca acacccaagt cacgcatttt ttcaaatgta gcaacatctt ctttgtccat
    78841 agacaaaacg gtattgacca atgttttacc tgttgagtga gccatagaac caacgttaag
    78901 agtcttgatt ggcacgccgc cttcgatggc acgaagggca tcttgaggtg tttcaaacaa
    78961 gataagggca tgtgtttctc caaaacgtgg gtcttttgaa atatcaatca gtttttgaat
    79021 tggaaccacg ttagccttga cattacctgg agctgcttgt ttaatcaatt ctttacgaag
    79081 gtcgtcttta gccacgttat ctgaagcaac gatgatacga tttgcttttg aatctggagt
    79141 ccaagcagtt gcaacctgac cgtgaagtag acgtgtgtca agacgggcaa gattgatttt
    79201 caatttaccg tctccgataa cagttccttc tgggatagca gcttgggcaa ctggagcagc
    79261 tgcagcgctt gcaacttctt caactggatt tagctcttct ggaagagctt tgatgccatc
    79321 tttggcttct ttaatgatat tagcaacgac tttttctaca cctgcagcag cgtccatgag
    79381 gcgctctgtg taggcttgaa tcaacatcgg taagttaagt cctgtgatga tggcaaactt
    79441 acgctcagga ttttctccca tcacgcgact agcttggtta aatggagaac cactccaaag
    79501 gtcagccaaa actagaacct catcttctgc gtcaaatgca gcaacagcgt tattaaactt
    79561 agcgtataga tcatcaggac cttcatttgg cataaaggtc acaacttgaa ccttttcttg
    79621 ttcaccaaag atcatagatc ctgactgatg aatacccgca gcaaattcgc cgtggctcgc
    79681 aataatgatt ccgatactca ttattgtcat tcctcctttt ttgttttagt tttcatttaa
    79741 gaaaacttta agactgttta agtataaacc gttttcataa aaaaagcaac tatttatcat
    79801 aaaaaattaa aaaattttta tttttgtatg ttgatatgtt gagtttttga ggagtaatct
    79861 tgaattctta tttaaaattt aatataaaaa agttggaaga agcttccaac ttttaaaata
    79921 ggtttctatt agattagtgg gtgaagtcga gtaccatacg tccttggatt tggccttttt
    79981 ccatttcgtc gaaaatggca acagcatctt ctactggacg tttttgaaca actgggacta
    80041 ccagaccttc tgcaccaaat tggaaggctt cttctaagtc tttacgagtt ccgacaagag
    80101 aaccgatgac ttggattcca tcgaggactg ttttaacgat gctgagttcc atcatttcag
    80161 aaggaagacc aacagcgacg acgcgaccac cagcacgaat ggagtcaaca gcctggttga
    80221 aggcaacttt agacacagca gttacgacag ctgaatgagc tcctccatca gttttttctt
    80281 taatgagtct agctacatct tcaacttcga ggccgttaat cacaatgtca gcgcctactt
    80341 cttttgcaag ggcaagtttg tcattgttga tatcgactgc gataacatga gcattgaata
    80401 cttttttagc gtattgaaca gcgaggttac caagtccacc agcaccgtaa agaacaaccc
    80461 attggcctgg ttcaactttt gcttctttga tagctttata ggttgttact ccagcacatg
    80521 tgatagaaga agcttgggct ggatcaagtc cgtcaggaac cttgacagca tagtcagcag
    80581 ttacgataca ttgttcagcc ataccaccgt ctactgagta gccagcattt ttcactgtac
    80641 ggcaaagggt ttcgcgacca gttgtacagt attcgcaagt gccacatcct tcaaagaacc
    80701 aagcaacgct gacgcggtca ccgactttaa ggcttttcac atctggagca atctctttaa
    80761 cgataccgat accttcgtgc ccaagaacac gtcctgggac ttgaccaaag tcaccatgag
    80821 caacgtggag gtcggtgtgg caaacgccac agtattcaac ttctacaagt gcttccccag
    80881 tttcaagtgg acggagtact ttttcttcaa tagcaacacc agtgctttct ggctttacaa
    80941 caacagcttt catagctatc ctccttgata ttgaccgaga acagggacaa cgggactgga
    81001 ttgatttttt gtcaacagag tcgagtgtga cgagctctct tgtatttata tgtgaagtat
    81061 atcacaaaag aaagcctttt ccaaggtttt ggagacaaaa agtagaacaa tcgattaact
    81121 ggttgatgag actgtgaaaa gagcacaaag accagcttgc aagctggtca tactcttcga
    81181 aaatctcttc aaaccacgtc agcttcatct acaacctcaa agcagtgctt tgagcaacct
    81241 acggctagct tcctagtttg ctctttgatt ctcattgagt atcagtatag gttataagaa
    81301 taagtcttgt agggttttgg caaccccatc ttggtcgttg gtaagggaaa tttgctcatc
    81361 tgcataaggg agtagctctg gattggcatt tttcatggca taacccttcc cagcaaaagc
    81421 gagcatttcg gtatcattgt gttcatctcc aaaggcaatc aaatcttttt tgtcacgatt
    81481 cattatcttg agcaagtagt ccaaagcaaa ggccttgttg acaccttttg gggtacattc
    81541 aaggatattg agcggacctc cccaggtatt gatagaaagt tgatgctggt agaaggcgtt
    81601 catgtctttt gccaaggcat atttgtcact ggctctggtc tgcaagagga tacagttagg
    81661 gttcttggtc accaattcag gctggaattg atcttcaggc tggaaagctt ctacaccaaa
    81721 tagtttggga ttggcaattt cttcattggg atttgtaatg tagaattttt tacgatattc
    81781 tccagcgata aaatcggctt gaatgtcctc tgaacgttga accatatcta gcagatattt
    81841 tttgtctaca gtcaaacact tttcaaaatc ccaaacttgg tctggtaaat gagtaaggga
    81901 tccgttgaag ttaatcatag gagtgtctaa gcccagttca cggtaaaaat cttttgacat
    81961 acggtaaggg cgacctgtcg taataataac ctgatggcct ttttcagcaa cttttttgat
    82021 ggtttttttg gtaaagtcag aaatttgact gtctgagttg agcagggttc catccaggtc
    82081 aactgcaata atttttttcg tcatatggac ctttctagtg tgttttcaga taagatgtct
    82141 tctattataa cagaaagcag gcagaaaagc agattccaaa caaaaaatga aattggatta
    82201 atttcttaaa caaatcaaac aaagacattg aaaaagtgaa tgataaatga tataattcta
    82261 ttattgttcg taaaaattaa aaggagattg atgatggaca aattatttaa actaaaagag
    82321 aacggtacag acgttcgtac agaggttctc gctggtttaa caactttctt tgcaatgagc
    82381 tatattctct ttgtaaaccc acaaatactt tcacaaacag gaatgcctgc tcagggcgtc
    82441 ttcctagcga cgattattgg tgcagtagcg ggtaccttga tgatggcttt ttatgctaac
    82501 ttaccttatg cccaagcgcc aggtatggga ctcaatgcct tctttacctt tacagttgta
    82561 ttcgggcttg gttattcttg gcaagaagcc ctagctatgg tcttcatctg tgggattatt
    82621 tcattgatta ttaccttgac aaatgttcgt aaaatgatca ttgaatcgat tcccaatgct
    82681 cttcgctcag ctatttcagc tggtatcggt gtcttccttg cctatgtagg gattaagaat
    82741 gctggacttt tgaaattcac gattgatcca ggcaactata ctgttgtagg agaaggggct
    82801 gacaaagctc aagcaacgat tgcagcaaac tcttcagcag ttccaggatt ggtcagcttt
    82861 aataatccag ctgttttagt ggctcttgca ggacttgcca ttactatctt ctttgtcatc
    82921 aaagggatta aagggggaat tattctctct atcttgacaa caactgttct tgctattgca
    82981 gttggtttgg ttgatttgtc tagtatcgat tttgctaata accatgttgg tgcagctttt
    83041 gaagatttga agacaatctt tggtgcagct cttggttcag aaggtttggg agctttggtt
    83101 tcagatacag ctcgcttgcc tgaaactctg atggccattc ttgccttctc attgacagat
    83161 atttttgaca caattggtac cttgatcggt acaggtgaaa aagttggtat cgtagcgaca
    83221 aatggtgaaa atcaccaatc agccaaattg gataaggctc tttactctga tttgattgga
    83281 acgacagtcg gtgccattgc aggtacttca aacgtaacga cttatgttga gtctgctgct
    83341 ggtatcggtg caggtggacg tactggtttg acagccttgg ttgtagctat ctgttttgcg
    83401 atttcaagct tctttagccc acttctagcg atcgtaccaa cagcggctac agctccaatc
    83461 ttgattatcg ttgggattat gatgcttggt agcttgaaaa atatccattg ggatgatatg
    83521 tctgaagcag ttcctgcctt cttcacatct atctttatgg gattcagcta ctctatcact
    83581 caagggattg cagttggttt cttgacttac actttgacta agcttgttaa aggtcaagtt
    83641 aaagatgttc atgtcatgat ttggattttg gatgccttgt ttatccttaa ctacatcagc
    83701 atggccttat aatagaatga cccaggggga tttcccccct tttttaatac aaaaggagat
    83761 aggtgatgaa agagaaaaat atgtggaaag aattgttgaa tcgtgcaggc tggattttgg
    83821 tctttttact tgccgtcctt ttatatcagg ttcccctagt ggttacctct attttgactt
    83881 taaaagaagt agccctgcta cagtcagggc tgatagttgc tggcctttca attgtggttc
    83941 tggctctatt tattatggga gctcgtaaaa ccaagttagc tagttttaat ttttcttttt
    84001 ttagagctaa agatttggca cgtttgggct tgagttattt agttattgtc gggtcaaata
    84061 tacttggttc cattttattg caaatgtcaa atgagacgac aacagctaac cagtctcaga
    84121 ttaatgatat ggttcaaaat agttcgttga tttccagttt cttcttgcta gccttgcttg
    84181 ctccgatttg tgaggaaatc ttgtgtcgtg ggattgttcc taaaaagatt tttcgaggca
    84241 aagagagctg gggatttgta gtcggtacga ttgtgtttgc tttattacat caaccaagta
    84301 atttaccttc tttattgatt tatggaggta tgtcgacagt tctatcttgg acagcctaca
    84361 agacccaacg tttggaaatg tcgatcttac ttcacatgat tgttaatggg attgctttct
    84421 gtttgttggc tcttgtggtg attatgagtc ggacattagg gatttctgtt taagattatt
    84481 gacaattgct tacttgtttc tactgggaga aagatgaatg aaatcgtgtc catctttttc
    84541 tttttatggt aaaatagaga aataatatga tgaaaagcct tgagggagtg accgatatgt
    84601 caagtaaagc caatcatgca aagacagcta tttgcggaat tatcaatgta accccagact
    84661 ccttttcgga cggtggtcaa ttttttgctc ttgagcaggc gctccagcag gctcgtaaat
    84721 tgataacaga aggagccagt atgctcgata tcggcggaga atcgactcgg ccgggaagta
    84781 gctatgttga gatagaagag gaaatccagc gtgttgttcc agtgatcaaa gcgattcgca
    84841 aggaaagtga tgtactcatt tctatcgata cttggaaaag tcaggtggca gaggctgctt
    84901 tggctgctgg tgccaatcta gttaatgata tcactggtct catgggcgat gaaaaaatgg
    84961 ctcatgtggt tgctaaagct ggagcgaaag tagtcatcat gtttaatcca gtcatggctc
    85021 gacctcaaca ccctagctcg ctcatattcc ctcattttgg atttaatcaa acttttacag
    85081 tagaagagtt agctgacttt gaaacattgc caatcgaaga cttgatggtg gctttctttg
    85141 aacgagcact agcgagagcg gcagaagctg gtattgcacc agaaaatatc ctgttggatc
    85201 caggaattgg ctttggtctg accaagaaag aaaatctcct ccttttacgg gacctggata
    85261 aactacatca gaagggctat ccaatctttc tcggagtgtc gcgcaagcga tttgtcatca
    85321 atatcctaga ggagaatggt tttgaagtca atcctgagac agagcttggt ttccgaaatc
    85381 gggacacggc ttcggctcat gtaactagta tcgctgcgag acagggtgta gaagtggtgc
    85441 gcgtgcatga cgtagctagt cacaggatgg cagttgaaat tgcctctgcc attcgtctgg
    85501 ctgatgaagc ggaaaattta gatttaaaac aatataaata agatgaaaga aattgaaaac
    85561 aatcagtgga ttgctaacta ccggacggat caaccgcatt ttggcttgga acgaatggtg
    85621 gaactgttag ctttgcgtgg caatccccat ctcaaactca aggtcctcca tatcggaggg
    85681 actaacggca agggatcgac tattgctttt ttgaaaaaga tgctagaaaa gctagggctg
    85741 agagttggcg tgtttagctc gccctatctc attcattaca cagaccagat tagcatcaat
    85801 ggggaatcga tctcagaagc gaggctagaa gctctcatgg cagactatca gtctttgctg
    85861 gagggagaag cggtcgccaa tttacagggc acaaccgagt ttgagattat cacagccctg
    85921 gcctatgact actttgcctc agagcaagta gatgtggcca tcatggaagt tggcatgggt
    85981 ggactttttg atagtaccaa tgtctgtcag cccattttga caggaattac aactattggc
    86041 ttggatcatg tggccttact tggtgacacc ttggaggcca tagcagagca gaaggcaggt
    86101 attatcaaac aagggatgcc cttggtaaca gggcgtattg ctccagaagc cttggctgtg
    86161 attgaccgca ttgcggaagg gaaagatgcg ccgagacttg cctacgggac agattatcag
    86221 gttcgtcatc aagacagtgt ggtgacaggg gaagtctttg actatacaag tgctgtcaga
    86281 caaggtcgct tccagactag cctgcttggt ttgtaccaaa tagagaatgc tgggatggcc
    86341 atagctttac ttgatacttt ttgtcaagaa gatggtcgag agctagcaag caatgacttt
    86401 cttggtcaag ccttggaaga aacaagttgg ccagggcgtt tggaaatcgt gtcaagagat
    86461 cccttgatga ttttggatgg agcccataat ccccatgcta tcaaggcctt gttggtaacc
    86521 ttgcaagaac gttttgcgga ttatcataag gaaatcctct tcacttgtat caaaaccaaa
    86581 gccttggagg atatgttgga cttgctggga gccatgccag ataccgagct tactctaaca
    86641 cattttgcgg atagtcgggc gacggatgaa agcgtgctga aagaggcagc taagtctaga
    86701 aatctcagct accaagattg gcatgatttt ctagagcaga atgtgacaga taaaaaagaa
    86761 gagaaacaaa cagttaggat tgtcacaggt tccttgtatt tcttgagcca agtgagggtc
    86821 tatctgatgg agaggaagaa cgagaatgga tacacaaaag attgaagcag ctgtaaaaat
    86881 gattatcgag gctgtaggag aggacgctaa tcgcgagggt ttgcaggaaa cacctgctcg
    86941 tgtagcccgt atgtatcaag agattttttc aggtcttggt caaacagcag aggaacattt
    87001 gtcaaaatcc tttgaaatta ttgacgataa tatggtggta gaaaaggata tctttttcca
    87061 taccatgtgt gaacaccact tcttgccatt ttatggtaga gcgcacattg cctacattcc
    87121 agatggtcgt gtggcaggct tgtctaagct agcccgtacg gttgaagttt attcgaaaaa
    87181 accacaaatt caagaacgtt tgaatatcga agtggccgat gccttgatgg actatctagg
    87241 tgctaaagga gcctttgtta tcattgaggc ggaacatatg tgtatgagta tgcgtggtgt
    87301 tagaaaacca ggcactgcaa ccttgacgac agtagctcgt ggtctatttg aaacagataa
    87361 ggacctccgc gaccaagctt atcgtttaat ggggctataa aaagaatccg tttcaagcgg
    87421 atttttctag aaaggaatca ttatggatca actgcagatt aaggatttgg aaatgtttgc
    87481 ctatcatggt ctttttccta gtgagaaaga attggggcag aaatttgtcg tttcagccat
    87541 cctatcctat gatatgacca aggcagctac agacttggat ttaacagcct ctgtccatta
    87601 cggagaattg tgtcagcagt ggacgacttg gtttcaggaa acgagtgaag atttgattga
    87661 aacggtagcc tataaactgg tggaacgtac ctttgagttt tatcctcttg tccaagaaat
    87721 gaagttggaa ctgaaaaaac cttgggcacc ggtgcatttg tcactagata cttgctcggt
    87781 aaccattcat cgccgcaagc aacgagcctt tatcgcctta ggaagcaata tgggagataa
    87841 acaagcaaac ttgaagcaag ccattgacaa actgcgagct cgtggcatcc atattctcaa
    87901 agagtccagt gtcttagcga cggagccttg gggtggagtg gagcaggata gctttgccaa
    87961 tcaagtggtt gaggtggaaa cctggctacc agcacaagac ttgttagaaa ccttgttagc
    88021 cattgagtca gagctgggac gggtgagaga agtgcattgg ggacctcgtt tgattgattt
    88081 ggacttgctc tttgtggagg accagatcct ttatacagac gacctcatat tgcctcatcc
    88141 ttacatagcg gaacgccttt ttgtccttga gtccttacag gaaattgcgc ctcattttat
    88201 ccatccgata ttaaaacaac cgatccgcaa cttgtatgat gctttgaaaa aatagaaaaa
    88261 ctctagtttt cagtcacttg caactgaagg ctagagtttt taaaataggt cattttcttc
    88321 tgggaggagg atagtttctc taccgtccat gtctaaaacc agtactcttg ggggataacg
    88381 agggtcgaaa ggatggttaa agtcaaaatc aatggctgta gggaggtgtt gacttgaaaa
    88441 gtggaaggta atctttcctt ggttattaag caattgaaac tcgagttctt cttccaattc
    88501 aaagacattt tttaagaaat ggtcgatgat ataccaaaaa gagtcaatga tgtcatcagg
    88561 caagctggta acaatgccaa aactagcaga ccgcatgtgg gtattggtaa aagccatata
    88621 tctgtcccct ttcttttccc ttatcataca gcaaatagga ttaaaaatca agaaaaggtg
    88681 attttttgaa aaggatttta gttacaggga gaaataggga aaaattccca aaaatctacc
    88741 gaagttaata ggtaacttcc caaattaact tgattatata actttcagtt attttgagaa
    88801 gttaccgaaa aatatttttc atatctattg acttttaggg gtgaaatttg gtatgatagt
    88861 aggcggtatt gtttacccca tttgaaaggc cccggaacct tccaaatact tttcgatggg
    88921 aaggaacacc catcaccgta aacaaaaatc gaactatata taggagaaat catgaacaaa
    88981 acaacattta tggctaaacc aggccaagtt gaacgtaaat ggtacgtagt tgacgcaact
    89041 gatgtaccac ttggacgtct ttctgcagta gttgctagcg tacttcgcgg aaaaaacaaa
    89101 ccaacattta caccacacac tgatacaggt gacttcgtga ttgttatcaa tgctgaaaaa
    89161 gttaaattga ctggtaaaaa agcaactgat aaaatctact acactcactc aaaccaccca
    89221 ggtggattga aacaaatctc tgcaggtgaa cttcgttcta aaaatgcagt acgtttgatt
    89281 gagaaatcag ttaaaggtat gcttccacac aatacacttg gacgcgctca aggtatgaag
    89341 ttgaaagtat ttgttggagc tgagcacact cacgctgcac aacaaccaga agttcttgac
    89401 atttcaggac ttatctaagg aaaggaacaa taaagtatgt cacaagcaca atatgcaggt
    89461 actggacgtc gtaaaaacgc tgttgcacgc gttcgccttg ttccaggaac tggtaaaatc
    89521 actgttaaca aaaaagatgt tgaagagtac atcccacacg ctgaccttcg tcttgtcatc
    89581 aaccaaccat tcgcagttac ttcaactgta ggttcatacg acgttttcgt taacgttgta
    89641 ggtggtggat acgctggtca atcaggagct atccgtcatg gtatcgctcg tgcccttctt
    89701 caagtagacc cagacttccg cgattcattg aaacgcgcag gacttcttac acgtgactca
    89761 cgtaaagttg aacgtaagaa accaggtctt aagaaagctc gtaaagcatc acaatttagt
    89821 aaacgttaat tcgaaagaat tactatactt atacagagca cctttcgggg tgttcttttt
    89881 ttatactttc ttactaaatt ggtgcaattg acacagttgt tgcgacttta gtcgcttaca
    89941 aatgtggctg caacctgaca aggtcagttg cctcaaaacg ttaatcaata cgattatatc
    90001 aacgtttcaa agcactcaaa agtttacctt atgggtgctt ttgtcttgtt cttgtttcaa
    90061 ttgactataa atcgctataa gaaaaaatca ttttattggt ataaagaagt gattgaaagt
    90121 aatggcgaaa cgttagataa ttagttcata aaaaacaagt ttagatcctc atctaaactt
    90181 gttttttaaa aattgaagga tgattttgga ggatataaga tgacattgac tattcatgta
    90241 tattataaag gtgatggaga tagtgcaata aagtttgcaa gagaaatgct tgatagtggc
    90301 cttgttgaag aaattagaaa tcaaaaaggt aacttgaaat acgaatattt tttaccaatt
    90361 gaaaaagagg gaactattct ccttattgat cagtggataa atcaagaagc tttagataag
    90421 catcatcaat caaagacaat gcagaaaatc ttagatttaa gaaaaaaata tcacttgcag
    90481 atgcaagttg aacgttatat agaagatgat tctgggatgc cagaaagcga taagtcgttt
    90541 atagacacag ggaattagaa ttattgtgag agtttttgta gtttgaaagt attgaaaatc
    90601 gtaaagatat cattacgaga atacaagaag atattgttct atttccatta aaaattactt
    90661 ctttccttaa caataaggaa aaagaatgcg ttttcatctt ttggtttgag gtttataata
    90721 agagtatcaa agtcaggagg aaaaaagatg actactttta aagatagatt tttatggggt
    90781 ggtgctgttg ctgctcatca acttgaaggt ggatggcaag aaggtggcaa gggaattagt
    90841 gttgctgatg ttatgactgc tggtcgtcat ggagtagctc gtgaaattac tttgggagtt
    90901 ttagagggta aatattatcc aaatcatgag gcgatagatt tttatcatcg ttataaagaa
    90961 gatatagcac tttttgctga aatgggattc aagtgcttcc gtacctctct tgcatggaca
    91021 cgtatctttc caaaaggtga tgagttagag ccgaatgaag aaggattaca gttttatgat
    91081 aatctttttg atgaatgctt aaagaatggt attgaacctg tcatcactct atctcatttt
    91141 gaaatgcctt atcacttagt gaccgaatat ggtggttgga aaaataggaa attgattgat
    91201 ttctttgctc gttttgcaga agtcgtattt aaacgttaca aagataaggt taaatattgg
    91261 atgactttca atgaaatcaa taatcaagcg aattatcagg aagattttgc accatttact
    91321 aactcaggta ttgtatatga ggaaggtgat aatagagagg caattatgta tcaagcagta
    91381 cattacgaat tagttgcttc tgcacgagct gtaaaaattg gtcatgagat taatccagat
    91441 tttcaaatag gttgtatgat tgcgatgtgt ccaatttatc cagctacttg caatcctaag
    91501 gatatcttaa tggcaatgaa agctatgcag aagcgttatt attttgctga tgtgcatgtt
    91561 ttaggtaaat atcctgagca tattttcaag tattgggaac gaaaaggtat ttcagttgat
    91621 tttactgccc aggataaaga agatttactt ggtgggactg tagattacat tggtttcagt
    91681 tactatatgt cctttgctat cgactctcat cgtgaaaata atccttattt tgattatctt
    91741 gaaacagaag atttagtgaa aaataattat gttaaggctt ctgaatggga gtggcaaatt
    91801 gatccagaag gtttacgtta tgcgttaaat tggtttacag accactatca cttaccactc
    91861 tttattgttg aaaatggttt tggagctata gatcaagttg cagcagatgg tatggtacat
    91921 gatgattata gaattgaata tctaggtgcc catattcgtg aaatgaaaaa ggctgtagtt
    91981 gaagatggtg ttgatttaat gggttatact ccatggggat gtattgattt ggtttcagct
    92041 ggtaccggtg aaatgcggaa acgttatggc tttatttatg tagataaaga tgacaatggg
    92101 aagggaagtt ataatcgttc cccgaaaaaa tcttttggct ggtataagga agttatttca
    92161 tctaacggtg aatcagtaga atagtataaa caaactgaga ttattctcag tttgtttagc
    92221 atattgaggt gacatatgat tggaagtatt gcagcaattt taacaacatt tgcattttta
    92281 ccacaagttt ttcgtgtagt taagacaaag gacacaggaa ctattgctct aggtatgtat
    92341 gttatgcaag ttattggtat tgcattgtgg cttgctcatg gtattcgtat aggagacttg
    92401 cctttgattt tagcaaatag tgtttcattt ctactctcag gaataatttt attttataaa
    92461 ttgaagtata aataattttt ttccatatca tttaggaaaa tgagggaatt gtcattggaa
    92521 acgctttatt ttataataaa aatagataac aaataagcca acttagcaca gctttgattg
    92581 gatttaagaa aaggagaaaa tattatggca aaagctttaa ttatttgtgc agcaggaatg
    92641 tcttcatcac ttatggcaca gaaaacaaca gagtttctaa aaggaaaagg gaaagatatt
    92701 gtagttgatg ctattagtgc tactgaagga gggaaagcta tcgcagcagc agcttttgat
    92761 ttgtatcttg tcagccctca aacaaaaatg tactttaagc aatttgaaga ggctggttct
    92821 aaagcaggaa aaccagttgt acaaatacct cctcaagcat atattcctat tccaatggga
    92881 attgaaaaaa tggctaattt gattcttgag aatatttgat gaacacatga aatgtcaata
    92941 aatatttagg ttaagataaa ttgttttgag tttgatataa actgatttaa gtgtataata
    93001 tgcttcaata tatgaaaaca tacgttttag gagggaatga atgtgttaaa cattaaagag
    93061 aaagatatcc ttcaattttt aataaaaaat aaggaacgtt ttgttacaag caaagaactg
    93121 gcagaatatt tatcctgttc agatagaact gtccgtaatg tactgaaatt aattgagaag
    93181 acaatgatta ttcaaggagt ccggttgatt tcaaaacaag gtcaagggta tcaaatattt
    93241 tttgagaatc aaggcgctta ccaggagttt agacaaactt atgaactgga agaagactat
    93301 acgaaaactg cggtttcaaa aggtgatgat cgtttagtat ttatcttaaa taaattatta
    93361 tttgagcaag ttccagttct ttttgatgat ttagctgatg aactttacgt tagccgttca
    93421 acattatctc atgatttcag aaagatacga gtgatgttat cagagtataa tttgtccatt
    93481 gagagtaggg cgaataaagg agtttatgtc tcaggcgagg aacgtgataa acgacgtttt
    93541 atcataaatt atttcctaga gaatcaattt tttaaaacaa tacattgcta tgtaaaattt
    93601 aacttttttg atcaaactgt tccattagaa gaatttgcta gaattgtttt ggatgaatgc
    93661 caagaggcca acctaaaact atctgatttt gtactacaga atttagtagt tcacatagca
    93721 ttgtctgtga ttcgtttaaa attcggattt gaaataaaaa atatagactg tcagatgact
    93781 gatgatgcaa tagagagaaa ggttgcccaa agaattcttt ctaaagtaag agaagtaaca
    93841 aatcaggaat ttccagttca ggaaatagac tacattactt tgcatttgtt agctaagagt
    93901 caacaatgtc aaaaaaatca gaagaatatt tctgaagaag ttttaaaaaa atctttattt
    93961 aaaacatttc agaatttagg attagatgat atgtataact tttcttcaga tttccaacta
    94021 attgaaggat tgataactca tctaatgaca ctacaagtac gtttagaaag ccggattacc
    94081 ttaaataacc ctttggtaga tgaaattaaa cagaattata gtgatatatt ctttatgact
    94141 agagaaattc ttgcaaatat ggacaagttc ttggagtgga caatatcaga tgatgaagta
    94201 gcatatgtaa gtcttcactt tttagctgct atggaacgta gcaaagagag tactaagttt
    94261 aatattcttg ctatttgtgc aacaggattt ggtgcagccc aaatgttaag aaatcgtttg
    94321 gaaacggagt ttgggaagcg agtagaagtt gttgatgtaa taggctatta tgaattgaat
    94381 caagaaaaac ttaaaggaat agattttata gtgtcagctg ttgatttatc aaatctatat
    94441 tttcaaatcc cagtttttaa agttagtgtg tttcttaaga gtgatgagat ggaaatgatt
    94501 agaaaagcta tggttcagat gcaagtttct agttatgtac aatcatcaaa gattaacaaa
    94561 tttgaaaaca acggctttag acagtatttt agtaaagaaa actttttaat atgtactgaa
    94621 tcagacaagg taaatttact tgaaaagatg gttgagagtt tatctgttgg tgaatcaaat
    94681 gagtttgaac aatctttact ttatggaatt aaacagcgcg aagaattaag ttcagttgtt
    94741 ttttctgaaa aaattgcagt tccgcatcct attcagccct ttggtacaga ggaaaaggtt
    94801 tcggttgcaa tttgtaaaga ttcgttactc tgggataatc aaagttcaca tgtccagcta
    94861 gtatttcttc tatctccatc aatatatggg aacgaaggtt tggcaactgt gactaaaaag
    94921 atagtctctc tgacagagaa tgatgaattg caaaatcagc taatatcttg caataacttt
    94981 gaagatttta ttaacatatt tgagaagata aaataggagg ttcatatgaa tcaagaggaa
    95041 ctgcaggttg cagcatttga aattatcctg cattcgggaa atgcaaggtc agaaatacat
    95101 gaagcatttg caaaaatgag agaaggtagt tttgatgatg cagaaagtaa attaaatcaa
    95161 tcaaatgaga taattcttga agcgcatcat gcacaaacca aactcttgca agaatacgca
    95221 agtggagtgg aaattaaaat tgaaattatc atggtacatg ctcaagatca tttaatgacc
    95281 actatgacat tattagaagt agcaaaggaa atgttagctc tttataagaa agttaactaa
    95341 atatgtgttg ttatataagg aggaaatgat atggataaaa aagaacgaca aaagattgaa
    95401 caacaacgtc gagagatggc tctaactaat acttttttta atcgatatct tcttctacgt
    95461 tattcaatag cactcttctt ttttgggaat atttattggc ttttgaatca gtttattaat
    95521 ccctcgccta ttattatttt ccccattatg ctcatagtat tttctatttt agcaactatt
    95581 gaacaattta aactttatgg aaataggaaa gaaaagttgg gaataacact aatgtttgtt
    95641 agaatacaaa tgcttatttc aataggatta cttgttttaa cttggacaag ttggtttaag
    95701 aatctttttc cgatttttga aaataaccaa gtagcacgtt tatttgtttt tgtagttctt
    95761 ctattaggtt tagttctgag tttgttagac attagaagaa ttaaaaaaat ttataaacga
    95821 acagataagg tttatcaaca atttgtccaa ttggaaaaga actcacttag tttataatcc
    95881 tgatctagta taatttgtat ttgaaactag tctttagaaa gtaaaaatta ttatgtttta
    95941 ttaaggaggt ctatttatgg atcaacaaaa cgggttgttt ggttttcttg aaaaccatgt
    96001 tatgggacca atgggcaaac ttgctcagtt taaagtagta cgtgctatca cggctgcagg
    96061 tatggctgct gtaccattta ctattgtagg atcaatgttt ttggtattca gtattttgcc
    96121 acaagctttc tcattttggc caattgtggc agatattttc tctgcttcat ttgataaatt
    96181 cacatcactt tacatggttg caaactctgc gactatgggt tctctatctc tttatttcgt
    96241 tctatcactt gcatatgaat tgacaaaaat ttatgcagag gaagaagaac tcaatatgaa
    96301 tcctcttaat ggtgccttgc ttgccttgat ggcttttgtc atgacagtac cgcaaatcat
    96361 ttttgatggt ggaatgatga agactgtgac aagtctaaaa gaaggtgcag taattgcaga
    96421 tggatgggca atgggaaatg gagtcgcacg ttttgggaca acagggattt ttaccgcaat
    96481 cattatggca attgtgactg ttcttattta tcgtatgtgt gttaaacata attgggttat
    96541 taaaatgcct gaagctgttc cagaaggagt ttctcgtgga tttaccgctt tggttccggg
    96601 atttgttgtt gcatttgttg ttatctttat caacggtctt cttgtagcaa tgggaacaga
    96661 tatttttaaa gtcattgcaa ttccatttgg ttttgtatcc aatctgacta attcgtggat
    96721 tggtttaatg attatttatc tattgactca actactttgg attgtaggta tccacggtgc
    96781 gaacattgtt tttgcatttg ttagtccaat tgctcttgct aacatggctg aaaatgctgc
    96841 tggcgggcac ttcgctgttg caggtgaatt ttctaatatg tttgtaattg caggtggttc
    96901 tggtgcaact ttaggactat gtttatatat tgcttttgcc tctaaatctg aacagcttaa
    96961 agcaatagga cgagcatctg tagttccggc cttatttaat attaatgaac cattaatttt
    97021 tggattacct attatctata atccagcctt agctatacca tttattttag caccaatggt
    97081 tactgctact atttattacg tagcgaattc tctaaacttt attaagccaa ttatcgcaca
    97141 ggttccatgg ccaactccag tagggattgg agctttctta gggacagcag atcttcgagc
    97201 tgtattagtt gctctagtat gtgcatttgc agcattccta gtctatcttc cattcatccg
    97261 tgtatatgat caaaaattgg tgaaagaaga gcaaggtatc taataagtaa aaaagtatac
    97321 tcgatgatag aatccatata gtttaaataa tgagcgttaa cattagcagt gaagaggtct
    97381 ttttaagata ttcttctctg ctttttcata ttttttcgct atgtagggta tgaagcaaaa
    97441 tagaaagtag ttcgaatagt tgataaacag ggaattgctg ttatttaaaa aaaaacaata
    97501 aagtaaagta tgttatcgta gaatacgata caatagtaaa aaagcaaaaa gaatgcgttt
    97561 tatatttggg tttgaggttt ataaaatagg ataagcatgc tgaaaactta gatatgacaa
    97621 acaaaataaa atttttaaaa gctacataga aacatggtat aatgtatcta aaggaggtag
    97681 catatgtcct tagatataga taaagaaaag atgacaatca tgggaatagc ttttgaaaac
    97741 cgatccgttt ttaggagtgt ttggtatgct ttaagtacaa atatgattga aggatggcga
    97801 cctacggtta gtgatgttga aaaattacga gatgaagctc ttgctctggg gatgacttaa
    97861 tgaagcgcaa ctgttatgag tcttatgact atgttgatcc ggataattta tataccgatc
    97921 cgggttcttc agttctaaga aataagcagg aaggaaaaaa gcacgcgagc ttgaatatcg
    97981 tatgattgct agtaagagtt tgaaattatt tatcaatcct atcttagtta atagtttaaa
    98041 agtagtttgt ttcacaactg cataagctta gaaaagttga aaagtgataa ctctttaata
    98101 aactcttggt ttgttaaaag atattttgtc cactacattt tttcaattga ctattatttg
    98161 tcatagatat aacagataga acattgcatt cagaataatg aaaaacgcat caaaaatggt
    98221 gcgttctgtt tttatgctac cataaaagga ggaaaacaaa ttgaaaattt ttaagggaga
    98281 gttttatcga atctctgtat taacagacaa gctagtaagg ttagaatact ctcgaactgg
    98341 aaattttgag gatagaacga cacaacttat ctataataga gattttggcc aagtttcgtt
    98401 agattatatc gagacatcaa atgtactaga tattatgacg gactattttc atctgcactt
    98461 taataaagga gaatttaacg ccgaaaattt atttatagaa ttaaaaggaa attttgccgt
    98521 atatggtagt cgctggtatt ttggtgaatc tattgaaacg ttaaaaggaa cagctcggac
    98581 tctggataag gcagatggag caatctcgtt agaagatgga attattagcc gaaatggtat
    98641 agccttattg gatgattctc aaggatttat ttgggatgaa caatctggtt atattgagag
    98701 agaaaatcaa attgacctgt atttctttgc ctatgggcat gattatagag gagcaatcag
    98761 agacttttac catttgactg gttcaacacc cttgttgcca agatatgctt taggcaattg
    98821 gtggagtaga tattggcctt atacgtcgga tgaatacttg gatttaatag acagatttga
    98881 aacagagaaa attccattat ctatcggtgt gttagatatg gattggcata taactgacat
    98941 tccagctcgt tttggaagtg gctggacagg atatagttgg aatagaaact taataccaaa
    99001 tccagaacag ttattgcaac aacttcatga tagaaagtta aaactctcct taaatgtcca
    99061 tcctgctgat gggatacggg cttatgaaga agcttatcct caaatcgcaa aacggttggg
    99121 gttaaatgta gaactagaag aacctgctat ttttgatttt tttaatccct cttttaggga
    99181 agcctacttt aaagatgttc attatgagct agaaaagcag ggagtagatt tttggtggat
    99241 tgactggcaa caagggacac aaggtatgct agattcactt tggcttttaa accattatca
    99301 ctatcaggat agttgtaaaa atgcagaagg tggtttgact ttatcaagat atgcaggtcc
    99361 tggtagtcac cgctaccctg ttggtttttc aggggatact attattagtt ggaattcctt
    99421 aagatttcaa ccctatttta cagcgacagc atctaatatc ggttatagtt ggtggagtca
    99481 tgatatcggt ggacatatgt tgggggatta tgacgaagag ctacaaacta gatggctaca
    99541 gtttggtgtt tttagtccga ttactcgatt acatagttct agaagtcctt ttaatagtaa
    99601 agaaccttgg tttttttcag aaacaacatc taagattatg aagaaatacc ttcgtttgag
    99661 acatcagatg attccctatc tatataccat gaatgtacag acacatgagg aaggtgcccc
    99721 attaatcagt ccaatctatt atttctatcc agagaatgat gagagctata atgttccaaa
    99781 ccaatacttt tttggaacag aactgatggt ggctcccatt gtagaaaaga tggatttgac
    99841 attccaatct gcaaaagtag atgtatggtt ccctgaaggt gaatggtatg acttcttttc
    99901 agagaaaaaa tacacaggtg gtgtgaagtt aagtgtttat agggacgttt cgaatattcc
    99961 tgtgtttgca aaaagtggtg caatcattcc cttggttggt tctgagatag gtatgggtgt
   100021 tgatttacct gaggttgtag attggtatgt attcccaggc aaacaacatt cttttgaaat
   100081 gcttgaagat caaaatggtc aaagatataa aacaagatta tcaatcgatt gggaaatggg
   100141 aatggtagag ttagcattac aaggagattc tagtatcgtt ccaagcaata gaaaacatag
   100201 aattcatttt aaaggaacga atgtgtctat aattgaattg ccaaataaga atgatacagc
   100261 taaatttgaa tggaaagata ataaaaggac atctttaaat gacgaagttt ttagactact
   100321 aaagacagct tctcttccat atgaattaaa agatagattg ttaaatcaat tcatcaatgc
   100381 gaaaaactct catgacttaa tgaatatctt gcatcatcag gataaggaat tgagagggcg
   100441 tttgttggaa atgatattta ctagccaaaa ctaattgata taattagaaa gtcatttgtt
   100501 tagtgtatat gaagattctg tatggtattc gttatcactg gtcacattga aaatgtgaaa
   100561 taagcaccta caacatagac tttacaacac ttcatgtttc atatcatggg gtgtttttct
   100621 atttaagtca aagccaatca aaaaatttca ctattcatca ggttaaagga aacctaatca
   100681 tagtgagatt gtgaattata gtagagtttg tatcgcctct tcaatttgtt ttgggtctgt
   100741 ttttgaagaa aagcgttcaa agacttgccc atcacgacca atgagaaact tagcgaaatt
   100801 ccattcgatt cgttttccta gtgggccaga tttatggtct tttaaccaga catagagagg
   100861 gtctgcttcc ttaccgttga ccttaatctt ggcaaaacgt gggaaggtgg tttgaaaatg
   100921 taggctacag aaggcgttga tttcctctgc gctgccgggt gcttgtccca taaactgatt
   100981 gcaagggaaa tccaatattt cgaagccctg atcttgatag cgttcataga gttcttgaag
   101041 tccctggtac tggggcgtta aaccacatcc agtagcagtg ttgacaatca agagaacttt
   101101 gccacgatag ctatccaagg gagttgcttg gttgttttgg ttcaaaacgg aaaaatcata
   101161 aagtgaagtc atgagggcct cttttctttt tctacattgt aacagttttt acttttttcg
   101221 tcgagtcgga tggaagatat tgttgaagaa taagccttca atatgataga aatcgtttac
   101281 aaataacttt aaaaatggta tgatttaatt aaaccggttt actttgttgc tataaatctc
   101341 taatttgaga tttagttcct attgatttta caatatgttt attggagtgt atacatgcaa
   101401 acaaaaacaa agaagctcat tgtgagtttg tcttcacttg ttttatcagg atttttatta
   101461 aaccattata tgacagttgg agcggaagaa acgactacga ataccattca gcaaagccag
   101521 aaggaagttc agtatcagca aagggataca aaaaatttag ttgaaaatgg tgattttggt
   101581 cagacggagg acggaagcag tccgtggaca ggaagcaaag ctcaggggtg gtcagcttgg
   101641 gtagaccaga agaatagttc tgcagatgcc tcaactcgag tcattgaggc taagggtggg
   101701 gctatcacta tctcaagcca tgagaaatta agggcagcgg ttcaccgtat ggttcctatt
   101761 gaagctaaga aatagtataa actgcgtttc aagattaaaa cagataataa agtcgggatt
   101821 gccaaggttc gtatcattga ggaaagtggt aaggacaagc gattgtggaa ttctgcaacg
   101881 acgtcaggaa caaaggactg gcagaccatt gaagcagact atagcccgac tttagatgtt
   101941 gataaaatca agctggagtt attctatgaa acaggaactg ggactgtttc ctttaaggat
   102001 attgagctgg tagaggtagc agaccagcct tctgaggatt ctcaaacaga taaacagctt
   102061 gaggaaaaga ttgatttacc aattggaaaa aaacatgttt tttctcttgc ggactatact
   102121 tataaggtag aaagtcctga cgttgcttca gtcaaaaatg gaattttaga acctcttaag
   102181 gaagggacaa ccaatgtcat tgtcagtaaa gatggcaagg aagtgaaaaa gattcctttg
   102241 aagattctag cctctgttaa ggatgcatac acagaccgtt tggatgactg gaatggcatc
   102301 atcgctggga atcaatacta tgattctaaa aatgaacaga tggccaaatt aaaccaggaa
   102361 ttggaaggaa aggtagctga tagcctatct agtatttcaa gtcaggcgga ccgcacctat
   102421 ttgtgggaaa aattttcaaa ttataaaatg tctgcaaatc tgactgccac ttatcggaaa
   102481 ttggaggaga tggccaagca agtgaccaat ccttcttctc gttattatca agatgaaact
   102541 gtcgttcgaa cagtcaggga ttccatggaa tggatgcata aacatgtcta caatagtgaa
   102601 aagagcattg ttgggaactg gtgggattat gaaatcggta cacctcgtgc catcaacaat
   102661 accttgtctc tgatgaaaga atacttctct gatgaggaaa ttaaaaaata tacagatgtg
   102721 attgaaaaat ttgtaccaga tcccgaacat ttccgaaaga cgactgataa cccattcaag
   102781 gctctaggtg gaaacttagt tgatatggga agggtaaaag taatagctgg tttactgcgt
   102841 aaggatgatc aagaaatttc ttctaccatt cgctcgattg agcaagtgtt caagttggta
   102901 gagcaaggtg aaggttttta tcaagatgga tcctatatcg accacaccaa tgttgcctat
   102961 acgggtgctt atgggaatgt tttgattgat ggcctgtctc aactgttgcc agtcattcaa
   103021 aagaccaaga atccaatcga taaagataaa atgcaaacca tgtaccactg gattgataaa
   103081 tcgtttgctc ctttgctggt gaatggagag ctgatggata tgagtcgtgg acgctcgatc
   103141 agtcgtgcaa atagcgaggg gcacgtggcc gcagtagaag tactaagagg gattcaccga
   103201 atagcggata tgtctgaagg agaaaccaaa caacgtttgc agagtcttgt gaagaccatt
   103261 gttcaatcgg atagttatta tgatgtcttt aagaatttga agacttataa ggatatcagt
   103321 ttgatgcaat ccttgttaag tgatgcagga gtcgcaagtg ttccaagaac aagttaccta
   103381 tctgccttta acaagatgga taaaacagcc atgtacaatg cagagaaagg gtttggattt
   103441 ggcttgtcac tcttttccag tcgtaccttg aattacgaac acatgaacaa ggaaaataaa
   103501 cgtggttggt atacgagtga tgggatgttc tatctttaca atggcgattt gagtcactat
   103561 agcgatggct actggccaac agttaatcca tataagatgc ctggtacaac agagacggat
   103621 gctaagagag cggatagcga tacaggtaaa gttttaccgt ctgctttcgt tggaacgagc
   103681 aaactagatg atgccaatgc gacagcaacc atggatttca ccaactggaa tcaaacattg
   103741 actgctcata agagctggtt tatgctaaag gataagattg cctttttagg aagcaatatc
   103801 caaaacactt caacagatac tgctgcaact acaatcgacc agagaaaact ggaatcaagt
   103861 aatccatata aagtctatgt caatgataaa gaagcctccc ttacagaaca agaaaaggat
   103921 tatcctgaaa cccaaagtgt ctttttagaa tcgtccgatt cgaaaaagaa tattggttac
   103981 tttttcttta agaagagttc aatcagtatg agtaaggctt tgcaaaaggg agcctggaag
   104041 gatatcaatg aaggacagtc agacaaggaa gttgaaaatg aatttcttac gattagtcag
   104101 gctcataagc aaaatggaga ttcttatggc tatatgctca ttcctaacgt gggtcgtgcc
   104161 accttcaatc aaatgataaa agagttagaa agtagcctca tcgaaaataa cgaaaccctt
   104221 cagtctgttt atgatgccaa acaaggagtt tggggcattg tgaaatatga tgattctgtc
   104281 tctactattt ccaaccaatt ccaagttttg aaacgtggag tctataccat tcgaaaagaa
   104341 ggggatgaat ataagattgc ctactataat cctgaaaccc aggaatcagc tccagatcag
   104401 gaagtcttta aaaagctaga gcaagcagct cagccacaag tacagaattc aaaagaaaag
   104461 gaaaaatctg aagaggaaaa gaaccattcg gatcaaaaga atctccctca gacaggagaa
   104521 ggtcagtcaa tcttggcaag tctagggttc ttgctacttg gggcgtttta tttattccgt
   104581 agaggaaaga acaactaatt tgttcatcat ctagatgaat tacatgaaac tgtggaaaat
   104641 agaaaaaatc cgaagaaggc caaatatctt cggatttttc ttttaaaaag ggataagttg
   104701 atacttatcc ttttttactt cattatgtga ctatagcgtt ttgaaactag aataggacgt
   104761 cataactact aaaagatttc tataaattca tttgattttc ctaatcaatt tgttcgtatc
   104821 ctatttcact ccactatatt agtccgtctc gctccgtgag gtgcgagaca aaacaaccac
   104881 ccgctatgcg ggtgcgcgtc gaagattata ccaaaaaaac tccaaacgcg atacaataaa
   104941 ggtgttcaat ccaattgtaa agcgaaagga gaaaaaatat ggcacaaaag actcatagtt
   105001 tatcatacac aaagtggatg tgttctatca tattgtgttc acccctaagt atagacgaaa
   105061 agtcatctat aatcaatata gaagtagttt aggcgaaata tttcatcgct tgtgtagtta
   105121 taaaggtgtt gaaatgatcg agggtcactt aatgccagac catgtacaca tgttagtcag
   105181 tattccacta aggctaagtg tttcaagttt tatgggttat ttaaaaggca aaagtgcact
   105241 catgatgttt gacaaacacg ccaatctcaa gtacaagttt gggaatcggc atttttgggc
   105301 ggaaggttat tatgtaagta cagtagggct taataaagcc acaattaaga aatatagtca
   105361 agattaaaga aattatccag tggatgattt cttcacgagt atgaaaattt gagaacgagt
   105421 aaagcatgat atatagtaaa atgaaataag aataggacaa aatcgatcag gacagtcaaa
   105481 tcgatttcta acaatgtttt agaagcagag gtgtactatt ccagtttcaa tctactatag
   105541 cactagataa attgagtgta aaagaatatg aggatccctt tagggatagt ggtaagtaat
   105601 accaaagtct cttaaagagg caagtgacga gtcaagagca ataaggcttg aacaacgtga
   105661 aagccagcgt ctttaggcgc tggctgatga tttgggctta tagctctgag ataaaccacc
   105721 cgttagacag gtggttatga ttttatctga gtgtaacata ctgttgggca atctcgctga
   105781 tgcggtcaaa gttgccttgg gaagcgagtt tattgagttc gccaccaatt ccaacggcgt
   105841 ctgcaccagc agcgaaccat tgagggatgt tgtttagacc gactcctccg gttaccatta
   105901 cggaaacttg tgggatcggt gccttgactg cagagatata tgctggactg agagtactac
   105961 ttgggaagag tttgatgatt tcactaccgg cttcaagtgc agtcgtgatc tctgtgaggg
   106021 taatacagcc tggaatgtac ggtgtgctgt agagattgca cattttcgca gtttcagcat
   106081 ggaaagatgg agaaacaacg taatttgctc cggctagaat ggcatctcta gcagttacgg
   106141 catcaagcac agtacctgca ccgatacaaa cactcttatc gtcctgatac aagtctacaa
   106201 gttccttgat gatttgtcct gcatactgat tggtataggc gatttcaata gctttgatac
   106261 cgcccttgat acaagcaatc gaggcttgca gtccttcttc ctttgtattt ccccgaatga
   106321 cagcgacaat tttctgtttt tttagttcaa taatcgtatc tgatttggtc atgtaattct
   106381 cctaacgaat gatatcttgt gcatttgcca gtaaattttc aatactagtt gcggaagtgg
   106441 agagatggtc tcctggaaga gtgcatttga gagttgcgct cgcaactgca aagtcaatgg
   106501 tagtttttag ggaggaatga tggagtagtt ggtaaagggc accagatata aaggcatccc
   106561 cgctaccaat tcgttgatag actgcagttt ttagttggac agactcttca aatagttctt
   106621 ccagagcata ggcttgatag acatttttgt cttgctcatc actagagcgg agggtatgga
   106681 aaatggcctt gaaaccatag gcttctttta aaagtcgcat gcgattttcc acctcttcta
   106741 ggctagcact gtctcttgga aacatctcta gattttggtc atcaatcatg agaggatcaa
   106801 taccgaagca atagtcagta aaacgtgcaa acttagaaaa ttcatacttg gcttctagga
   106861 ctgaaatcat ctttgttctc agattgagat ccattgaaac gacaattcct cggcgcttgg
   106921 cttcttccaa gagtaggaga aggatcgtac ggacctcttg accgatagct acggtgattc
   106981 cactaaaatg aaaatggcta atcccctgaa agagagaatc catatctagc atgtttggct
   107041 gaatctggct gatactcgta tgcttacgat cgtagaaaac ttcactttga cgacaaccaa
   107101 agccgttctc caaatagtag aggccgattc gatcgccaag ccgacagatt gaactggtat
   107161 cgatttggtg ctgtttcaag aatgtgagaa aacgatctcc aatctcgttg gcagggagtg
   107221 cggtaaagac tttcgttgag atacccaggg cttgcaaatt acaagcgatg ttaatttctg
   107281 atccgccaaa ataagtcgaa ctggcaacat gatcgccgat actggtggca tctaatggtg
   107341 agattcgaat taatggttcg ccaaacagta atattttcgt catccattag ttcctttctg
   107401 gtttagaata gctttacttg gctaatactt ctttcaaata agcagcgact tcatcatctt
   107461 ggcagttttc aaagaagtat tcttggaagt atttgccaga gatggtgtct ttgaggaagt
   107521 cttggtcgat tgttttaagg atggtcatca aatcattgtg ggtgatttgt ttcacctcgt
   107581 ttaagatacg agcgttgcgt tgttcaggga ttacacgttc tcttgggtag ccaccgccca
   107641 tttcttcagc aaataagcgt tcaaacatca atttgagggt cagttctgcc ccccagccaa
   107701 atcctttggc ataagggata gacaaggcgt taccaccatt gatttgagaa taaaggtaag
   107761 cgtcagttgg gtccactgct agaccacaga caacaccagg gaagctgttt aaagcaagca
   107821 tagcccctac acccgtacca cagccggtaa caacaaagtc aactgccttt gtatttaaaa
   107881 ggatggcagc cattagtccg ttctgcacat aagttaattg actttctcct tcttctccac
   107941 gcataccata gttaaataat tggtagcctt ttttatctgt cgcttctttt agactatcgt
   108001 aaataatgtg attcttgcta gcttgactat tttcattgat taatgcgatt ttcataagat
   108061 cttctttcta tttttactca ggttgttttc cgatgtaggc taagataccg ccatctacat
   108121 ataggatgtg gccattgaca aaattgctgg catcactagc gagaaagaca gcagggccca
   108181 tcaaatcttc aggatttccc caacgtgcag caggtgtttt tgcaatgatg aactggtcaa
   108241 atgggtggcg agaaccatct tcttgcaatt cacgaagagg tgctgtttga ggagtggcaa
   108301 tataacccgg tccaattccg ttacattgga tattggctcc accgtattca gacgcaatgt
   108361 tgcgggtcaa cattttcaag ccccctttag cagcagcata agcgctaact gtttcacgtc
   108421 ccagttcgct catcatcgaa caaatattga taatctttcc atgccctttc tttatcatag
   108481 aaggaataac tgcctttgaa acgataaatg gtgcgtttaa gtcaatatcg atgaccttac
   108541 ggaaatcagc ggcgctcatt tcgcacattg gaactcggcg gataatacca gcgttattaa
   108601 cgaggatgtc aatgacacca acctcttgtt cgatttgctt gaccatggct tggataccgt
   108661 cctcgtctgt cacgtcacag acatatccat gggcttcgat gccaacttca cgataagctt
   108721 caatcccttt attgaccaga tcttgattga tatcgttaaa gacaatagta gcgccggctt
   108781 cagcgtagga tttggcaata gcaaatccaa ttccataaga agcgccggtg atgagagcaa
   108841 tttttccttt taaagaaaac tgctcaattg agaatgatgt atttgtcatt tgatacttcc
   108901 tttcaaattt gttaagactt ctctataacc aaattatatt ctagtaaacc ggttttgtca
   108961 ataaataaat atttttattt ataaaaagat ttgttttcct aaaaaaacgg aagattttga
   109021 aattt
//
LOCUS       DAVKMO010000002        98886 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVKMO010000002 DAVKMO010000000
VERSION     DAVKMO010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 98886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 98886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..98886
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.002"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(98..1459)
                     /gene="dnaA"
                     /locus_tag="VW361_000117"
     CDS             complement(98..1459)
                     /gene="dnaA"
                     /locus_tag="VW361_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU9743266.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(1672..2430)
                     /locus_tag="VW361_000118"
     CDS             complement(1672..2430)
                     /locus_tag="VW361_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU9743267.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(2488..3669)
                     /locus_tag="VW361_000119"
     CDS             complement(2488..3669)
                     /locus_tag="VW361_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEU9743268.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            3852..4331
                     /gene="rlmH"
                     /locus_tag="VW361_000120"
     CDS             3852..4331
                     /gene="rlmH"
                     /locus_tag="VW361_000120"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU9743269.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            4375..4448
                     /locus_tag="VW361_000121"
     tRNA            4375..4448
                     /locus_tag="VW361_000121"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4409..4411,aa:Arg,seq:tct)
     gene            4614..4739
                     /gene="comC"
                     /locus_tag="VW361_000122"
     CDS             4614..4739
                     /gene="comC"
                     /locus_tag="VW361_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU9743270.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            4760..6085
                     /locus_tag="VW361_000123"
     CDS             4760..6085
                     /locus_tag="VW361_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9743271.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHLICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIATFLFPLGLYSYFRWIKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            6082..6834
                     /locus_tag="VW361_000124"
     CDS             6082..6834
                     /locus_tag="VW361_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9743272.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            6886..6957
                     /locus_tag="VW361_000125"
     tRNA            6886..6957
                     /locus_tag="VW361_000125"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6919..6921,aa:Glu,seq:ttc)
     gene            6963..7036
                     /locus_tag="VW361_000126"
     tRNA            6963..7036
                     /locus_tag="VW361_000126"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6997..6999,aa:Asn,seq:gtt)
     gene            complement(7077..7619)
                     /locus_tag="VW361_000127"
     CDS             complement(7077..7619)
                     /locus_tag="VW361_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU9743273.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            7798..8565
                     /locus_tag="VW361_000128"
     CDS             7798..8565
                     /locus_tag="VW361_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEU9743274.1"
                     /translation="MIGISLIPALYNIIFLSSMWEPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDQLVSGSNTLTQKSSRLTAGVG"
     gene            8650..8988
                     /locus_tag="VW361_000129"
     CDS             8650..8988
                     /locus_tag="VW361_000129"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743275.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKS"
     gene            9016..9330
                     /locus_tag="VW361_000130"
     CDS             9016..9330
                     /locus_tag="VW361_000130"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HEU9743276.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(9431..11983)
                     /locus_tag="VW361_000131"
     CDS             complement(9431..11983)
                     /locus_tag="VW361_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU9743277.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDIALRNILHGNSSLVYTFTSGLGLNFYALSSYYLGSFLSPLVYFFDLTNMP
                     DAIYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGIASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGITKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(12045..13667)
                     /locus_tag="VW361_000132"
     CDS             complement(12045..13667)
                     /locus_tag="VW361_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9743278.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIHSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            13873..14898
                     /gene="trpS"
                     /locus_tag="VW361_000133"
     CDS             13873..14898
                     /gene="trpS"
                     /locus_tag="VW361_000133"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU9743279.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            15050..16528
                     /gene="guaB"
                     /locus_tag="VW361_000134"
     CDS             15050..16528
                     /gene="guaB"
                     /locus_tag="VW361_000134"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU9743280.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(16579..17676)
                     /gene="recF"
                     /locus_tag="VW361_000135"
     CDS             complement(16579..17676)
                     /gene="recF"
                     /locus_tag="VW361_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU9743281.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSDQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(17679..18047)
                     /gene="yaaA"
                     /locus_tag="VW361_000136"
     CDS             complement(17679..18047)
                     /gene="yaaA"
                     /locus_tag="VW361_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU9743282.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            18206..19456
                     /locus_tag="VW361_000137"
     CDS             18206..19456
                     /locus_tag="VW361_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9743283.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPPLFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            19453..20736
                     /locus_tag="VW361_000138"
     CDS             19453..20736
                     /locus_tag="VW361_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9743284.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDCFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESMSQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            20778..21599
                     /locus_tag="VW361_000139"
     CDS             20778..21599
                     /locus_tag="VW361_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9743285.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            21610..22155
                     /gene="pgsA"
                     /locus_tag="VW361_000140"
     CDS             21610..22155
                     /gene="pgsA"
                     /locus_tag="VW361_000140"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU9743286.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            22152..22979
                     /locus_tag="VW361_000141"
     CDS             22152..22979
                     /locus_tag="VW361_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9743287.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPV
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            22964..23803
                     /locus_tag="VW361_000142"
     CDS             22964..23803
                     /locus_tag="VW361_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9743288.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            23796..24590
                     /locus_tag="VW361_000143"
     CDS             23796..24590
                     /locus_tag="VW361_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9743289.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            24649..25467
                     /gene="mreC"
                     /locus_tag="VW361_000144"
     CDS             24649..25467
                     /gene="mreC"
                     /locus_tag="VW361_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU9743290.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVVDIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            25467..25961
                     /gene="mreD"
                     /locus_tag="VW361_000145"
     CDS             25467..25961
                     /gene="mreD"
                     /locus_tag="VW361_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU9743291.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            26055..27233
                     /locus_tag="VW361_000146"
     CDS             26055..27233
                     /locus_tag="VW361_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU9743292.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAERATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            27457..28236
                     /gene="rpsB"
                     /locus_tag="VW361_000147"
     CDS             27457..28236
                     /gene="rpsB"
                     /locus_tag="VW361_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU9743293.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            28315..29355
                     /locus_tag="VW361_000148"
     CDS             28315..29355
                     /locus_tag="VW361_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU9743294.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            29601..29924
                     /gene="tnpB"
                     /locus_tag="VW361_000149"
     CDS             29601..29924
                     /gene="tnpB"
                     /locus_tag="VW361_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU9743295.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALTSEQVDWLMKGFS
                     ITPKI"
     gene            complement(30079..30366)
                     /locus_tag="VW361_000150"
                     /pseudo
     CDS             complement(30079..30366)
                     /locus_tag="VW361_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            30357..30755
                     /locus_tag="VW361_000151"
     CDS             30357..30755
                     /locus_tag="VW361_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9743296.1"
                     /translation="MKAPIPKAPLAHSFGSASIIAHTIHQKFNLKVPNYRQEEDWAKM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(30952..31872)
                     /gene="cysK"
                     /locus_tag="VW361_000152"
     CDS             complement(30952..31872)
                     /gene="cysK"
                     /locus_tag="VW361_000152"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU9743297.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLVLAPDNGERYLSTALYEL"
     gene            complement(32157..32792)
                     /locus_tag="VW361_000153"
     CDS             complement(32157..32792)
                     /locus_tag="VW361_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU9743298.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            32848..34146
                     /locus_tag="VW361_000154"
     CDS             32848..34146
                     /locus_tag="VW361_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9743299.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            34143..34805
                     /locus_tag="VW361_000155"
     CDS             34143..34805
                     /locus_tag="VW361_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU9743300.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSIKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            34885..35433
                     /gene="raiA"
                     /locus_tag="VW361_000156"
     CDS             34885..35433
                     /gene="raiA"
                     /locus_tag="VW361_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU9743301.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            35569..37542
                     /locus_tag="VW361_000157"
     CDS             35569..37542
                     /locus_tag="VW361_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU9743302.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFIANFISEFSEKHMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            37539..37991
                     /gene="rplI"
                     /locus_tag="VW361_000158"
     CDS             37539..37991
                     /gene="rplI"
                     /locus_tag="VW361_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU9743303.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            38035..39387
                     /gene="dnaB"
                     /locus_tag="VW361_000159"
     CDS             38035..39387
                     /gene="dnaB"
                     /locus_tag="VW361_000159"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU9743304.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            39389..39655
                     /locus_tag="VW361_000160"
     CDS             39389..39655
                     /locus_tag="VW361_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743305.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            39744..41090
                     /gene="cbpD"
                     /locus_tag="VW361_000161"
     CDS             39744..41090
                     /gene="cbpD"
                     /locus_tag="VW361_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU9743306.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      41173..41275
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            41347..41637
                     /locus_tag="VW361_000162"
     CDS             41347..41637
                     /locus_tag="VW361_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU9743307.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            41600..42358
                     /locus_tag="VW361_000163"
     CDS             41600..42358
                     /locus_tag="VW361_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9743308.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            42397..43404
                     /locus_tag="VW361_000164"
     CDS             42397..43404
                     /locus_tag="VW361_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9743309.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            43404..44132
                     /locus_tag="VW361_000165"
     CDS             43404..44132
                     /locus_tag="VW361_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743310.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AETISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            44251..44709
                     /locus_tag="VW361_000166"
     CDS             44251..44709
                     /locus_tag="VW361_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU9743311.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLVSVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            44711..47143
                     /locus_tag="VW361_000167"
     CDS             44711..47143
                     /locus_tag="VW361_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9743312.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVSAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            47464..48117
                     /gene="rr06"
                     /locus_tag="VW361_000168"
     CDS             47464..48117
                     /gene="rr06"
                     /locus_tag="VW361_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU9743313.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            48114..49445
                     /gene="hk06"
                     /locus_tag="VW361_000169"
     CDS             48114..49445
                     /gene="hk06"
                     /locus_tag="VW361_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU9743314.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLLNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            49528..50055
                     /locus_tag="VW361_000170"
     CDS             49528..50055
                     /locus_tag="VW361_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU9743315.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            50155..50286
                     /locus_tag="VW361_000171"
                     /pseudo
     CDS             50155..50286
                     /locus_tag="VW361_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558199.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            50333..52450
                     /gene="pspC"
                     /locus_tag="VW361_000172"
     CDS             50333..52450
                     /gene="pspC"
                     /locus_tag="VW361_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEU9743316.1"
                     /translation="MFASKSEKKVHYSIRKFSIGVASVAVASLFMGSVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAKKKVEEAKKKAKAQKEEDYRNY
                     PTITYKTLELEIAEFDVKVKEAELELVKKEADESRNEGTINQAKAKVESEKAEATRLK
                     KIKTDREKAEEEAKRRADAKEQDESKRRKSRVKRGDLGEQATPDKKENDAKSSDSSVG
                     EETLPSPSLKPGKKVAEAEKKVEEADKKAKAQKEEDRRNYPTNTYKTLELEIAESDVK
                     VKEAELELVKEEAKESQNEEKIKQAKAKVESKKAEATRLEKIKTDRKKAEEEAKRKAA
                     EEDKVKEKPAEQPQPAPAPQPEKPTEEPENPAPAPKPEKPAEQPKAEKPADQQAEEDY
                     ARRSEEEYNRLTQQQPPKIEKPAPAPQPEQPAPAPKTGWKQENGMWYFYNTDGSMATG
                     WLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMA
                     TGWLQYNGSWYYLNANGDMATGWFQYNGSWYYLNANGDMATGWLQYNGSWYYLNSNGA
                     MVTGWLQNNGSWYYLNANGSMATDWVKDGDTWYYLEASGAMKASQWFKVSDKWYYVNG
                     SGALAVNTTVDSYRVNANGEWVN"
     gene            complement(52680..53660)
                     /gene="dusB"
                     /locus_tag="VW361_000173"
     CDS             complement(52680..53660)
                     /gene="dusB"
                     /locus_tag="VW361_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU9743317.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(53647..54519)
                     /gene="hslO"
                     /locus_tag="VW361_000174"
     CDS             complement(53647..54519)
                     /gene="hslO"
                     /locus_tag="VW361_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU9743318.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKIAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            54684..56111
                     /locus_tag="VW361_000175"
     CDS             54684..56111
                     /locus_tag="VW361_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9743319.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            56270..57778
                     /gene="glpK"
                     /locus_tag="VW361_000176"
     CDS             56270..57778
                     /gene="glpK"
                     /locus_tag="VW361_000176"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU9743320.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEIDD"
     gene            57925..59751
                     /gene="glpO"
                     /locus_tag="VW361_000177"
     CDS             57925..59751
                     /gene="glpO"
                     /locus_tag="VW361_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU9743321.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARNLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            59821..60525
                     /locus_tag="VW361_000178"
     CDS             59821..60525
                     /locus_tag="VW361_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9743322.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            60822..61025
                     /locus_tag="VW361_000179"
     CDS             60822..61025
                     /locus_tag="VW361_000179"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743323.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(61112..61720)
                     /locus_tag="VW361_000180"
     CDS             complement(61112..61720)
                     /locus_tag="VW361_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743324.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            62756..64033
                     /gene="ltrA"
                     /locus_tag="VW361_000181"
     CDS             62756..64033
                     /gene="ltrA"
                     /locus_tag="VW361_000181"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEU9743325.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     SIVASIDERLPTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQLVAQK
                     SVLKRAISKPVLEKRGLVSCLDYYLERHALKVS"
     gene            64490..65201
                     /locus_tag="VW361_000182"
                     /pseudo
     CDS             64490..65201
                     /locus_tag="VW361_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            65396..65646
                     /locus_tag="VW361_000183"
                     /pseudo
     CDS             65396..65646
                     /locus_tag="VW361_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
     gene            65960..66091
                     /locus_tag="VW361_000184"
     CDS             65960..66091
                     /locus_tag="VW361_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU9743326.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            66112..67662
                     /gene="dltA"
                     /locus_tag="VW361_000185"
     CDS             66112..67662
                     /gene="dltA"
                     /locus_tag="VW361_000185"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU9743327.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            67659..68903
                     /gene="dltB"
                     /locus_tag="VW361_000186"
     CDS             67659..68903
                     /gene="dltB"
                     /locus_tag="VW361_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU9743328.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMRGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            68917..69156
                     /gene="dltC"
                     /locus_tag="VW361_000187"
     CDS             68917..69156
                     /gene="dltC"
                     /locus_tag="VW361_000187"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU9743329.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            69149..70417
                     /gene="dltD"
                     /locus_tag="VW361_000188"
     CDS             69149..70417
                     /gene="dltD"
                     /locus_tag="VW361_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU9743330.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMRHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            70572..71012
                     /gene="adcR"
                     /locus_tag="VW361_000189"
     CDS             70572..71012
                     /gene="adcR"
                     /locus_tag="VW361_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU9743331.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            71012..71716
                     /locus_tag="VW361_000190"
     CDS             71012..71716
                     /locus_tag="VW361_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9743332.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            71709..72515
                     /locus_tag="VW361_000191"
     CDS             71709..72515
                     /locus_tag="VW361_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9743333.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTISTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            72525..74030
                     /gene="adcA"
                     /locus_tag="VW361_000192"
     CDS             72525..74030
                     /gene="adcA"
                     /locus_tag="VW361_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU9743334.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDAKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(75192..75965)
                     /locus_tag="VW361_000193"
     CDS             complement(75192..75965)
                     /locus_tag="VW361_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9743335.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            76141..77544
                     /locus_tag="VW361_000194"
     CDS             76141..77544
                     /locus_tag="VW361_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU9743336.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKEE
                     YGLCDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYFQKN"
     gene            77659..78297
                     /locus_tag="VW361_000195"
     CDS             77659..78297
                     /locus_tag="VW361_000195"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU9743337.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            78309..78749
                     /locus_tag="VW361_000196"
     CDS             78309..78749
                     /locus_tag="VW361_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU9743338.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSVSCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            78742..79173
                     /locus_tag="VW361_000197"
     CDS             78742..79173
                     /locus_tag="VW361_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9743339.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            79164..79634
                     /locus_tag="VW361_000198"
     CDS             79164..79634
                     /locus_tag="VW361_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9743340.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            79659..80432
                     /locus_tag="VW361_000199"
     CDS             79659..80432
                     /locus_tag="VW361_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9743341.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            80429..81229
                     /locus_tag="VW361_000200"
     CDS             80429..81229
                     /locus_tag="VW361_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9743342.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            81288..83582
                     /locus_tag="VW361_000201"
     CDS             81288..83582
                     /locus_tag="VW361_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU9743343.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            83592..86708
                     /locus_tag="VW361_000202"
     CDS             83592..86708
                     /locus_tag="VW361_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU9743344.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDSNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGVRYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSSAIPLSLAEVEVYGSKRTPKKLSNIALAKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKEDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNDYEVFTQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            86791..88557
                     /locus_tag="VW361_000203"
     CDS             86791..88557
                     /locus_tag="VW361_000203"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU9743345.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            88703..89854
                     /locus_tag="VW361_000204"
     CDS             88703..89854
                     /locus_tag="VW361_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU9743346.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            89999..90883
                     /locus_tag="VW361_000205"
     CDS             89999..90883
                     /locus_tag="VW361_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9743347.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            91327..91579
                     /locus_tag="VW361_000206"
                     /pseudo
     CDS             91327..91579
                     /locus_tag="VW361_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            91567..91857
                     /locus_tag="VW361_000207"
     CDS             91567..91857
                     /locus_tag="VW361_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743348.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(92261..93592)
                     /locus_tag="VW361_000208"
     CDS             complement(92261..93592)
                     /locus_tag="VW361_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU9743349.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(93614..95125)
                     /locus_tag="VW361_000209"
     CDS             complement(93614..95125)
                     /locus_tag="VW361_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU9743350.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            complement(95336..96283)
                     /gene="arcC"
                     /locus_tag="VW361_000210"
     CDS             complement(95336..96283)
                     /gene="arcC"
                     /locus_tag="VW361_000210"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU9743351.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            complement(96448..97464)
                     /gene="argF"
                     /locus_tag="VW361_000211"
     CDS             complement(96448..97464)
                     /gene="argF"
                     /locus_tag="VW361_000211"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU9743352.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            complement(97522..98751)
                     /gene="arcA"
                     /locus_tag="VW361_000212"
     CDS             complement(97522..98751)
                     /gene="arcA"
                     /locus_tag="VW361_000212"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU9743353.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
BASE COUNT        30855 a        16822 c        20990 g        30219 t
ORIGIN      
        1 tctgtggaaa acagccttta aacaagtcat atcaagtttt ttagcttgtt taaaaaatgt
       61 ggataaaaaa gataaaaaac taaaagttat ccacaaatta tttgattttc tttttgattg
      121 attcaatttc taaacgtaaa ttatcgtctt gatcaatcaa agattttatt ttggcatggg
      181 catgaatgac tgtggtatga tcttttcccc caaattcctt cccaattttt ggaagactat
      241 tatctgttag ttctctagat aaatacatgg ctacttgacg ggccaaaaca atattttgaa
      301 ggcgtctact tcccttcatt tctttgatac taacaccata aaagttacca acttcagttt
      361 ggattttatc aattgggatg acgagcattt ggctaacatc ttgtttgcgg gctctaatgg
      421 cttctgcagc aatatcaata gtgatatcct tgattttttt tactctggca attaaagtga
      481 tgtcgttgat ggctccctca agatctcgaa catttgaatc aaattgccca gctaggtatt
      541 ctagagtatc actttggaaa ttgtagccta aatgttccgt cttactttgt aaaatggcaa
      601 tacgtgtttc aaagtcaggg ggtgtgatag tttgtgtcaa tccccaacta aaacgcgtga
      661 caagcctctc ctcgagccct tctagatgtt ttggactacg atcactcgtt aggacaatct
      721 gtttttgctt gtcatgaagg gcgttaaagg tattgaaaaa ttcttcctga gttgcgactt
      781 tttttccgct gagtgactgt atatcatcga ttaacaaaag atcaagacta cgataggtct
      841 ttttaaactt ttccatttcc ccaagtctta ggtgatcaag aaagtcatta ataaagcttt
      901 cggcagggat atatttaaca cgcgcattag gaatattttt tagaatttca tttccaatag
      961 cgtttaataa gtgagtctta ccaaggcctg gtcctccata gataaaaaga gggttatagg
     1021 tcagagccaa atcttcagag acagctaaag cggctgatac agcccaaaca tttccatccc
     1081 cttgaataaa gttatcaaag gtatactttt cttttaatcc cgtatctgaa taaggaatag
     1141 atactaactt tggactatag tcataaagag ttaaatttgt agcttcttca acttgtgagc
     1201 tagtcgtatc ttgaggtttg gtgaaaatat agtggggagt tatttcagcg tcataaattt
     1261 caaaaccagc tactacaata atatctttta gttgtttttc ccagaccatt tccatttcag
     1321 agcgaggtag aaatatagtg gcaacatttt cctctacctt gatgagttca gcttgaatag
     1381 catagaaatc atacatggat cgagtcagtc tttcttgtgc aaattctaat atacgattcc
     1441 aaaattgttt ttctttcaat cctttctcct cctttactat ttaaaagttt aatactagag
     1501 atattttacc atagatagca agaattttcc acaagctgtg aaaaataatc cacaatgtta
     1561 ccaaacttta tccacaggtt ggggataaaa gaagaaatta ttgatttatt aagcttttta
     1621 tcgaaaaaca tagtggataa ccttgtgaga taaaaaaata aaagaacagc cttatttcag
     1681 gctgttgata attctactat attcttcttg atttgaaaaa gaaataatga tttttccact
     1741 gtctttttta gatagtttaa tttctacatc taatccgagt agttttctta actgtttttc
     1801 ttcattttgt atgaaatgat tagttttttg ctgtttcttt tgttttttct ctgtcagaag
     1861 agtttctaac ttccttacag aaatatcttc ttctataatc cgttgaaaga aatagtcttg
     1921 ttgttcctta tttaacccaa ctagggaacg cgcatgggct tgtgatagtt tgccattttc
     1981 tacttctgag agaatctgtt ctggcaagga aagtaaacga atggagttgc tgatatatgg
     2041 acgagacttg cccatcttat ctgcaatttc agcatgggtg aatcctttct ctacgagaga
     2101 ttcataggcg cgtgcttctt ctattgggtt taaattttct ctctgtaaat tttcaataat
     2161 ggactggacc atcatctctt ggtctgaaat ctgtttaaca acagctggga tagaccgtag
     2221 accagctaaa agtgaagccc gatagcgtct ctctcctgca aggatttcat aaccaataac
     2281 aggagattga cgaacaataa tcggttgaat gaccccattt tctttgatag actgtgctag
     2341 ttcatctagc ttttctctat caaattcttt tcggggttga tagggatttt tttgtatatc
     2401 tgtgatagaa atcatttcaa atttttccat gattctacac taacacatct tttctcttat
     2461 gtaaagcttt ctttacatag atgtcaatta agattctaaa tcacctgaac tcttgttaag
     2521 tttgatagag gtagtttctt ctttcccgtt acgatagtag gttatcttaa tggtgtctcc
     2581 gatagaatgg ttgtaaagag cactttgtaa gtctgttgat gaagcaatct ctttgtcatc
     2641 tacttttgta attacatcgt atttttcaag gtgaccattg gcaggcatat tactttgtac
     2701 cgaacgaaca attacaccag atgtaacatt acttggaata ttgagtcttc tgatgtcgct
     2761 tgtactcaca ttagataaat taaccatctg gattcccaaa gctggacgcg tcacttttcc
     2821 gtttttttct aactgttcaa taatattgat agcatcattt gcaggaattg cgaaaccaag
     2881 accttctaca gatgttcctc catttgtagc aattttactt gaggtaattc cgataacctg
     2941 cccttgaata ttgatcagtg ggccgccaga gttacctggg ttaatagcag tatcagtttg
     3001 gatggctttt gtagaaatag cttgtccatc ttccgatttt aaggatacat ttctattgag
     3061 actggatacg ataccttgag tgacagtatt tgcatattca gaacctaacg ggctaccgat
     3121 ggcaatagca gtttctccta cagttaactt actagaatca ccaaactcag ctactgttgt
     3181 cactttttct gaagagattt tgacgacagc aatatcagag aaagtgtcag ctccgacaat
     3241 ttctccaggt actttagtcc catctgacaa tcgaatatct actttgctgg cgccatttat
     3301 aacgtgattg ttggtgacga tgtaagcttc tttatcattc tttttataaa taactccaga
     3361 tccttcacta gagattcgct gagaatctgt gtcagtatca tcattgccaa atacgctatt
     3421 ttgtctgttt gccgaataag taataacaga aacaacagca tcttttactt tgttaacggc
     3481 ctgtgttgtt gaattttcgt tcttataggc agtttgtgta atagtactat tgttgttaga
     3541 gttgtttaca ctactttttt gagttagttg agttattgaa aaactaccca aggctccact
     3601 aaaaaagcta atgacgataa cgactaataa ttgaaaccat tttttgtaaa atgtttttag
     3661 atgtttcata tttgcctcca tatgtttgaa ttactgaaag tataaactga ctagcttaat
     3721 tataacttaa acacaaaagt tttacacaaa ctgtggataa ctcttttgaa actgtgattt
     3781 tcttaattga aatctatttt ttattttgtg aataagatgt gaaaaaatag agaatatgtt
     3841 agaatagagt catgaaaatt aaagttgtaa cagttgggaa actgaaagaa aagtatttaa
     3901 aagatggtat cgcagagtat tcaaaacgaa tttctagatt tgctaagttt gaaatgattg
     3961 agttatcaga tgaaaaaaca ccagataagg ccagtgaatc agaaaatcaa aagattttag
     4021 aaatagaagg tcagagaatt ttatcaaaaa ttgctgaccg tgatttcgtt attgtgttag
     4081 ccattgaagg gaaaactttc ttctcagaag aatttagtaa gcagttagaa gaaacttcta
     4141 taaaaggatt ttctactctt acttttatta ttgggggaag tttaggattg tcatcatctg
     4201 taaaaaatag agccaatctt tctgtcagtt ttggtcgcct aaccttgcct catcagttaa
     4261 tgagactagt tcttgttgaa caaatctatc gcgcttttac gattcagcag ggattcccct
     4321 accataaata gagaattgac ttttaattga atttttggta gaataattgt gttaggtctc
     4381 atagctcagc tggatagagc attcgccttc taagcgaacg gtcgcaggtt cgaatcctgc
     4441 tgggatcaat ataatagcaa agctgggaat tttcccggct tttttcttaa aaaagtacac
     4501 tttgggagaa aaaaatgaca gttgagagaa ttttatctaa aacgaaattc cattttgtat
     4561 aatggttttt gtaagttagc ttacaagaaa aaaacatttt aggagatttt attatgaaaa
     4621 acacagttaa attggaacag tttgtagctt tgaaggaaaa agacttacaa aagattaaag
     4681 gtggggagat gaggctgtca aaattcttcc gtgattttat tttacaaaga aaaaagtaat
     4741 gaaataaggg gaaagagtaa tggatttatt tggatttggg acagttattg ttcatttttt
     4801 aattattagt cacagctacc atttaatttg taaaggtcaa ataaatagaa aagaattatt
     4861 cgtttttggt gcttatacat tactaacaga aatagtattt gattttccct tatatattct
     4921 atatttagat gggttaggga ttgcaacatt tttatttcct ttgggcctat attcctattt
     4981 tcgatggata aaacagtatg agagggatag aggactattc ctaagtttac tactatctct
     5041 tttatatgag agcactcata actttctgtc cgtaactttc tcctctataa caggagataa
     5101 ttttgtttta caatatcatt tcccattctt tttcgttgtg acggtgttga cctattttgt
     5161 tacattaaaa atcatttatt atttccattt ggaactagcc tattttgaca aggactacct
     5221 ttatcctttc ttgaaaaaag tattttttgc tttactattg ctacatattg tatctttcgt
     5281 ttcagatatg gtaagtacga ttaaacattt gaatagtttt ggaagtattt tgtcatctat
     5341 tgtctttatc tctctccttt tgaccttctt tgcaatgaat tctcataaag ttcaaatgga
     5401 gaaagagatt gctttgaagc agaagaaatt tgaacagaaa catttacaga attacacaga
     5461 tgaaattgtt ggtctgtata atgaaatccg tggttttcga catgattatg ctggaatgct
     5521 tgtcagcatg cagatggcaa ttgacagtgg taatttacag gaaattgaca gaatttacaa
     5581 tgaagtttta gtcaaagcaa atcataaatt gcgttcagat aagtacactt actttgattt
     5641 gaacaacata gaagactcag ctttacgaag tttggttgct cagtcaattg tctatgctcg
     5701 aaataatggt gtagagttta cactggaagt aaaagatacg attaccaagc ttccaattga
     5761 actattggat ttggttcgta tcatgagcgt tttattgaat aatgctgtcg aaggatcggc
     5821 tgatagctat aaaaagcaga tggaagtagc agttattaag atggaaactg aaacagttat
     5881 tgtgattcag aattcatgta aaatgacgat gactccttca ggagatctat ttgccttagg
     5941 attctccact aagggaagaa atcgcggagt cggattaaat aatgtgaaag aactactaga
     6001 taagtacaac aatattattt tagaaacaga gatggaaggc agtacattta gacaaatcat
     6061 tagatttaag agggaatttg aatgaaagtt ttaattttag aagatgttat tgaacatcaa
     6121 gtgagactag agagaatatt ggatgaaatt tcgaaagaat cgaatattcc aatatcatac
     6181 aagacaacgg gaaaagtccg tgaatttgaa gaatacattg aaaatgatga agtaaatcaa
     6241 ctttatttcc tagatatcga tattcatgga attgagaaaa agggatttga agtggctcag
     6301 ctcattcgtc attacaatcc ttacgctatt atcgtcttta tcactagtcg atcagagttt
     6361 gcgactctaa cctataaata ccaggtatca gccctagatt ttgttgataa ggatatcaat
     6421 gatgagatgt ttaagaagag aattgagcaa aatatcttct acacgaagag tatgttactt
     6481 gaaaatgaag atgttgtaga ttatttcgac tacaattaca agggaaatga tttaaaaatt
     6541 ccttaccatg atattttgta tattgaaaca acaggggtct ctcataaatt gcgcattatt
     6601 ggtaagaatt ttgcaaaaga gttttatggt accatgacag atattcagga aaaggacaaa
     6661 catactcagc gattttattc tcctcacaag tcatttttgg taaatatagg caatatcaga
     6721 gaaattgatc gaaaaaactt agaaattgtt ttctatgaag accatcgttg tcctatttca
     6781 agattaaaaa ttagaaaatt aaaagatatt ttagagaaaa aatctcaaaa gtgattgaca
     6841 attagcaaga aattgatata atggttatat ctgctacaga tagaaggtcc gttggtcaag
     6901 gggttaagac accgcctttt cacggcggta acacgggttc gaatcccgta cggactattt
     6961 tatccgccat agctcagttg gtagtagcgc atgactgtta atcatgatgt cgtaggttcg
     7021 agtcctactg gcggagtata gataaaaggg aacacagctg tgttcctctt tttgtatcaa
     7081 tttgtatcac caagcatttt cataaggaag tctgttattt cttgagaact ttcttttttt
     7141 ccatgtgcaa tccaagtttg gcagacacca aaaagtgcat gagttagata gatgctacta
     7201 tattctaatt cagtggtatt tagattcagt tgcataaatc gcttttgtaa atctgtactg
     7261 agcatgatat gaagtttatt tcgtaagaaa ttttggattt ctttagtccc attttcagaa
     7321 agaagggcag ccagaagtgg ttctgactct agatattcaa aaacttctaa aatagcgtct
     7381 cttttgtgat gagcatgttt ttgaaaaata tattcaaatg tatggaatag cttgctttga
     7441 tagtgctcaa tcatatcata cttatcctta tagtgagtat agaagctgga acgactaatt
     7501 ccggcttttt ctactaattt gacagtagaa attttatcaa atggctgttc catcagtaat
     7561 tgtaccatag cgttttcaat agttcgcttt gtttttaagc gtttgttact ttcttgcata
     7621 tttcctcctt gtaaacaaat tagactatat gtctaaaaat agatttttta tcttgtaatt
     7681 tagatttttt aatgtataat ctattatatc aaaattttag acaatatgtt taaaaaagga
     7741 gaaactatgt ttaaagaatg gaaagcaatt taaaaaaaaa caacctttat tattgtcatg
     7801 atcgggattt ctcttattcc agctctgtac aatatcatat ttttgtcatc aatgtgggag
     7861 ccatatgggc aattgtctga cttacctgtg gcagttgtaa ataatgataa agaggcttcc
     7921 tataatggta atactatggc aataggaaaa gacatggtgt ccaatttaaa agaaaataaa
     7981 accttggatt ttcattttgt agatgaagag gaaggaaaga agggattgga agatggcgat
     8041 tactatatgg tagtgacttt accaagtgat ttatctgaaa aaacaactac attatccaat
     8101 attcaatcga cagcagctta tcaatcattg acaagtgagc aacaaactga gataagtgat
     8161 tctgtatctc aaaattcaac tgatagtatt caatcggctc aatcaattgt agctttagta
     8221 caagatttac agggaagttt agaaaactta caaaatcaat cttctaatct ttcgacttta
     8281 aaaaatcaat ctaatcaagt atcacctatt acttctactt ctttgatagg attgtcaagt
     8341 ggattaacag agatacaagg agatgttact agcaaattag ttcctgccag tcagtcgatt
     8401 gcatcaggtg taaacgcata tactacaggt gttgataaag tttctcaggg cgcaagtcaa
     8461 ctaagtgaaa aaaatgccac cttgacaggt agtttggatc aactagtttc aggctcaaac
     8521 accttgacac aaaaatcttc tagattaaca gcaggagttg gttaattaca atcaggatct
     8581 gggcaattag cagacaaatc cagtcagtta ctttcaggtg cttctccatt agagaataga
     8641 gctaataaat tggcagatgg atctgggaaa ctagcagaag gtggaacaaa gttaacttct
     8701 ggattggaag atttacagac aggacttgct tctttaggac aaggactagg taatgctagt
     8761 gatcaactca aatcagtatc aacagaatct aaaaatgcag agattttgtc aaatccactc
     8821 aatctttcaa aaacagacaa tgatcaagtt cctgtaaatg gaatcgcaat agctccttat
     8881 atgatatcag ttgctctttt tgttgcagca atatcaacaa atatgatatt tgcgaaattg
     8941 ccttcaggac gtcatccaga gagccgttgg gcttggttga aatcttgagc tgaaataaat
     9001 ggtattatag ctgttttggc aggaattttg gtatatggag gagttcagct tattggttta
     9061 actgctaatc atgagatgag aatatttatt ctcatcatcc taacaagttt agtattcatg
     9121 tctatggtga ccactttagc aacgtggaat agccgtatag gagctttttt ctcacttatt
     9181 ttgcttttac tacagttagc atcaagtgca ggtacttatc cacttgcttt gacaaatgat
     9241 ttctttagat ctattaatcc ctggttacca atgagctatt cagtttcggg attacgacaa
     9301 acaatctcta tcaacaagtc attttcctag ctgtcatact agctctattt actggtttag
     9361 gtatgctagc ctatcaacat aagaaaatgg aagaagatta aaaaaatcga ccgattaact
     9421 ggtcgatttt ttatgcctta gatgactttc gtctgtgatt atagattcca aatagtaaga
     9481 gagaagtaaa ggaacagatt gctccagtaa taaaaccatt gggaatgaag gaaagtgtaa
     9541 tagttccttt ccccttggga atgtcaactt tcataaatcc agtttgagct tgtttaattt
     9601 ctattttctt accatcttgg taggcagacc aacctttgtc ataaggaatg gtgaagaaaa
     9661 tagatgtatc ttgttggaca tcatatgtag caaaaacctt gtttttagaa gttgatactg
     9721 tgacaggttg ttctttaatt ttttgaattg cctcggtgaa agttttggta tctaaacgat
     9781 agaaggtagg agattcaaat gatacttgtg aatttccagg gaaactaaca ttgatattga
     9841 aagttttttt ctctttagta tatcctagat taaagaagga gaagacatta tcagttgtaa
     9901 aagtcttttt ttcaccattt acaaggatgt caaccttctt ttgtttatcg ttagaaaagt
     9961 gaaggtttat gaaagagaga taaacttggc tgttttctgg aacttcaatt tgatactgga
    10021 ttgctgcatc ttcatttgaa gaacttgtga cactaatcaa atcattagta ttttctattt
    10081 tttctgtttt ttcataaggt attggagaaa aataatcaaa attgacgtta gcaagttgat
    10141 ttaaaaatga ggcctgatta tccaaggtat gttcattgaa cttgacatca ttgtaaacag
    10201 attgactagc aactgcaatc ggaagagagt attgattttc atatagggta agattatctt
    10261 tttgatagat atctttaaaa ccatacttat caataggact gtctgagata ttgtactgga
    10321 taccaaataa actatcagcc aaaatactat tatttgcata tcggagattg agattagtcc
    10381 cagaggattt aaaaccaagt ttatctaaag tagagcttga tgaacgattt cgaacagatg
    10441 aaaattgaga gattccattg tagttgaatt tcatactgtc atttcctgtc tgagtttgta
    10501 gtttttcagt acgagtaaat tgatttccaa tatatgttga gaaagattcc atagctggga
    10561 tatctcgact ataagcactt cgagaagcaa atccccattc cttagtaatt ccgtccattt
    10621 gagatgaagc atttaaactc atttcaacca gtataaataa agagattaga atggcaaata
    10681 gattcacaga tataaacttt ttgataactg caaggagtaa aagagaatag acaaccaaaa
    10741 attcaagagt aagcagaata ttcaaatctg ttaaaaaaga ataatgcgat tttagataga
    10801 tggtagctaa aaatcctgtt actacaagaa aaagcgaaac taaaaaattc cagactttaa
    10861 gttctttcag acgctttaag acttctgctg ctgtgtaaat taacaaggta gagaaaatcc
    10921 aagcatagcg atgtaaaaac atgtttggag tatgcatgcc ttgccaaaat aagtcaagag
    10981 cttctatgta aaagcttgca attagaaatg caaagaatat tacatatatg agtttcacgt
    11041 gaaacttaat agatttcagc gtaaaaaata aaatggtcaa aataaaggga agtagtccaa
    11101 caaaaatcat tgggatggcc ccatactttg ttgtgtcaaa ggaaccaatg aattgcttag
    11161 caaagagatc aagataccag ctactttcag tttgaaactt tgtaacttca gtcaattttt
    11221 ccccatgtgt ctgtaaatca aacagagtgg gaagagtcat aatcaaacta gctataccag
    11281 ctaaaaagga gataactatg aaatcaagaa cagatgattt tcgagtctta aagtcccacg
    11341 aaatttgaca gagataccag aaaataagaa acaatactgt catatatcca aaataataat
    11401 tttgaataaa taagattgac agacttgtaa agtacaatag gagtttcttt tcagttatca
    11461 gtagatgtaa accagttata attaaaggaa tcaagataaa aacatctagc caggttttta
    11521 tctctaattg actgacagtg aaactcatca gagcatagga agtagataag gctagtttta
    11581 aagtctgagg gatagattga aacaatttat tcaaactaaa aaaggttgac agaccaatca
    11641 atccaaattt taagagagtt gtcagataga tagcatctgg catattcgtt agatcaaaaa
    11701 agtaaaccag aggtgagaga aaactaccca agtaataact agatagagca tagaagttta
    11761 gccctagacc acttgtaaag gtgtaaacca gactactatt tccatgtagg atatttcgta
    11821 aggctatatc aaaaataacg tattgatgaa agccatctcc taatagagga gagttgtcgc
    11881 tattccagta gataccttga gatagatata ctccagacat aatcactaca ggaatgatga
    11941 aagaaataaa ataggttcga tatgttttta aaaatgattt catgttacct cgtagaatga
    12001 tagaaaactc agttggttaa cccaactgag ttttgaagtt ttatttagtc tttccaaagt
    12061 tctttaactt ttgcttgtac ttctgcattt tctaggaatt catcgtaggt ttcatcgata
    12121 cggtcaatga cgccattttt agataagaca atgatatggt tagccaaagt ttgaataaac
    12181 tcgtggtcat ggctggcaaa gatgattgat tctttaaagt ttttcaatcc atcattcaag
    12241 cttgagatag attccaagtc caagtgattt gttggatcat caagtacaag gacatttgat
    12301 tttaagagca tgagttttga aagcatgaca cgaacttttt ctccccctga caagacattt
    12361 acaggtttgt taacttcatc tccagagaag agcatacggc cgaggaagcc acgtaggaaa
    12421 gtattgtcat cttcttcttt acttgcgaat tgacgcaacc agtcaagaat tgattctcct
    12481 cctgcaaaat cagctgagtt atcttttggt aggtaagatt gactagttgt aactccccac
    12541 ttgacagttc cttcatagtc aatatctccc atgattgcac gaattaatgc agtcgtttga
    12601 atatcatttt gtccaataag tgctgtctta tcatctggac gcaagatgaa actaatatta
    12661 tccaagatag tttcaccatc aatctttaca gttagatttt ctactgtcaa gagatcatta
    12721 ccaatctcac gttccgcttt aaagttgata aatggatatt tacgactaga tggtacaatc
    12781 tcttctagct caatcttatc aagcattttc ttacgtgatg ttgcctgcct tgacttagaa
    12841 gcattggcag agaaacgagc aacaaattct tgcaattgtt taattttttc ttctgcttta
    12901 gcattacggt ctgctagcaa tttagcagca agctcagaag attccttcca gaagtcgtag
    12961 tttccgacat agagtttgat ttttccaaag tcaaggtcgg ccatgtgagt acaaactttg
    13021 tttaagaagt gacggtcgtg ggatactacg ataactgtgt tatcaaagtc aatcaagaag
    13081 tcttctaacc aagtaatcga gtggatatcc aaaccgttag taggctcgtc caagagaaga
    13141 acatctggtt taccaaaaag tgctttggcg aggagaacct ttactttttc accgttggcc
    13201 aattcgctca tgttttggta gtgtaattct tctggaatgt ttaggttttg aagtagttga
    13261 gaggcttcac tctctgcttc ccaacctcca agttcggcaa attctccttc gagttcggca
    13321 gcacgaaccc cgtcctcgtc tgagaaatct tccttcatgt agatagcatc tttctctttc
    13381 atgatgctat aaagtttttc atttcccatg ataacgacat caatggcacg ttcatcttcg
    13441 tagtcaaagt gattttgacg aagaacagag agacgttcat ctggaccaag agagatgtga
    13501 ccagtagtag gttcgatatc tccagctaaa atttttaaaa aggttgattt tccggcacca
    13561 ttagcaccga ttaatccgta agtatttcct tctgtaaatt tgatattgac atcatcaaaa
    13621 agtttgcgat cactaaaacg tagtgaaaca tcagatactg taagcaatat ttttctccta
    13681 tatgtgtaat atatttattc tactagaaaa tacagaaata ttcaaatttt tatttgtcaa
    13741 ttttgtgtaa attatattta cagtatcctt tacacaaatc tgtaaaaagc aaggctgatt
    13801 tattttgata aattacggtt atttcattaa aaaaatgcta taattgaaag gactatatcg
    13861 aaggagaaca aaatgactaa acccattatt ttaacaggag accgtccaac aggaaaattg
    13921 catattggac attatgttgg aagtctcaaa aatcgagtat tattacagga agaggataag
    13981 tatgatatgt ttgtgttctt ggctgaccaa caagccttga cagatcatgc caaagatcct
    14041 caaaccattg tagagtctat cggaaatgtg gctttggatt atcttgcagt tggattggat
    14101 ccaaataagt caactatttt tattcaaagc cagattccag agttggctga gttgtctatg
    14161 tattatatga atctagtttc gttagcacgt ttggagcgaa atccaacagt caagacagag
    14221 atttctcaga aaggatttgg agaaagcatt ccgacaggat tcttggtcta tccaatcgct
    14281 caagcagctg atatcacagc tttcaaggct aattatgttc ctgttgggac agatcagaaa
    14341 ccaatgattg agcaaactcg tgaaattgtt cgttctttta acaatgcata taactgtgat
    14401 gtcttggtag agccggaagg tatttatcca gaaaatgaga gagcagggcg tttgcctggt
    14461 ttagatggaa atgctaaaat gtctaaatca ctaaataatg gtatttattt agctgatgat
    14521 gcggatactt tgcgtaaaaa agtaatgagt atgtatacag atccagatca tatccgcgtt
    14581 gaggatccag gtaagattga gggaaatatg gttttccatt atctagatgt ttttggtcgt
    14641 ccagaagatg ctcaagaaat tgctgatatg aaagaacgtt atcaacgagg tggtcttggt
    14701 gatgtgaaga ccaagcgtta tctacttgaa atattagaac gtgaactggg tcctattcgt
    14761 gagcgccgta ttgaatttgc taaggatatg ggagaagttt ataatatgat tcaaaaaggt
    14821 agtgaaagag cgcgtgaagt tgcgggtcaa accctatctg aggtaaaagg ggcaatggga
    14881 cttcattact ttaactaagt ttattttaca agaaactatc atttctatct cgaagaaaag
    14941 atagtttttt atttacccct gtaacatttg acaaattttt atagaatggt atgatagata
    15001 caatataaaa agagtcaagc tcaaaaagaa agaaaagagg aaacttcgaa tgtctaattg
    15061 ggacactaaa tttttgaaaa aaggttttac ctttgatgat gtattgctta ttccagctga
    15121 aagtcatgtg ttgcctaacg atgcagattt aacaactaaa ttggcagata atttgacttt
    15181 aaatatccca attattaccg ctgccatgga cacagttaca gagagtcaaa tggccattgc
    15241 tattgctcgt gcaggtggtc tcggagttat ccataaaaac atgtcaattg ctcaacaagc
    15301 agacgaggtt cgtaaggtaa aacgttctga aaatggagtt attattgatc cgttcttctt
    15361 gacgcctgaa catacaattg ctgaagcaga tgagcttatg ggtcgttacc gcatcagtgg
    15421 tgttccagtt gttgaaacac ttgaaaatcg taaattggtt ggtattttga caaaccgaga
    15481 tcttcgtttt atttcagatt ataatcaacc aatttcaaac catatgacta gtgaaaatct
    15541 tgttactgct cctgtgggta cggatcttgc aacggctgag agtattcttc aagagcatcg
    15601 tattgaaaaa cttccgttgg tcgatgaaga aggcagtctt tctggtttga tcactatcaa
    15661 agatattgaa aaagttattg agtttccaaa tgcggctaaa gatgagtttg gtcgtcttct
    15721 agttgcaggt gcagtaggtg ttacttcaga tacatttgaa cgtgcagagg ctctttttga
    15781 ggcaggagcg gatgcgattg ttattgatac tgcacatggt cattctgcag gtgtcttgcg
    15841 taaaattgcc gagattcgtg ctcatttccc agatcggact ttgattgctg gaaatattgc
    15901 tactgctgaa ggtgcacgtg ccctttatga agcgggtgta gacgttgtta aggttggtat
    15961 tggaccaggt tctatctgta ctactcgtgt gattgctggt gttggtgttc cgcaagtaac
    16021 agctatctac gatgctgcag ctgttgcgcg cgaatatggt aaaacgatta ttgctgacgg
    16081 tgggatcaag tattctggag atattgtaaa agcacttgct gcaggtggaa atgctgttat
    16141 gcttggatct atgtttgctg gaactgatga agctccaggc gaaactgaaa tcttccaagg
    16201 acgtaaattc aagacttacc gtggtatggg atcaattgct gctatgaaga aaggttcaag
    16261 cgaccgttat ttccaaggtt ctgtcaatga agcaaacaag cttgttccag aaggaattga
    16321 aggtcgtgtt gcttataaag gagcggcagc tgatattgtt ttccaaatga ttggtggtat
    16381 tcgctctggt atgggttact gtggtgcagc taaccttaaa gaactacacg ataatgctca
    16441 atttattgaa atgtctggtg ctggtttgaa agaaagccat cctcatgatg tgcaaattac
    16501 taatgaggca ccaaattatt ctatgtaaaa aacaatgaaa agaactccag tgaaaacagg
    16561 agttctttta caatgttgtc aatttccatt tacagcagct ttaccatcct gaatagtgaa
    16621 gatacttaga ttttctggca gattttgaag atggtctaag cttgttgttg tgataaaggt
    16681 ttggattgat tgagaaatcg tttctaataa ttttaactgt ctagtgttgt caagttcact
    16741 catcacatcg tcaagcagta atatcggaga ttctgtggta atgctttcca ttaattcgat
    16801 ttctgctaat tttatcgaga ggacgagact acgatgttga ccttggcttc cgaaactagc
    16861 atccatccca tttatataaa aagaaatgtc atctcgatga ggaccgacac cagtattctt
    16921 tttaaataaa tctctggatc tacttttttc taaagcaatt ttgaaagatt cggataagtt
    16981 ttgtttgtca gttatattga cagaagattg ataggatatt gacaactctt cgatctgatt
    17041 agagagttca aaatgtttct tacgcccaaa tgattctagt ttttttatga aatctaagcg
    17101 gtgattcatt acacgacatc cataatcaac tagctgatca tctaacacag aaaggaatgt
    17161 ttcatctatt ttttgatctg attttaggta agtgtttctt tgctttagga tgtggttata
    17221 attggttaag tcagataagt agattggctt aatttgccca agttccatat caatgaattt
    17281 tcgtcgaatc gaaggtgctc ctttaattag ttgtaaatct tcaggagcaa ataagacaac
    17341 attcatgtgt cctacataat ctgaaagtcg tgcctgtttt aagtgattaa cttttgttac
    17401 acggcctttt tgtgttagtt cgatttctag gggaatggat ccagtttttt tctgaacgag
    17461 acctgaaaga tgaagttgtt cttcatcaaa atgaatgaga tttttatctg ttcgagttcg
    17521 atgactacgc gttaaggcta aaaaatagat agcctctaac atgtttgttt ttccttgtgc
    17581 attacgtccc aaaaagacat tcaatttagg attaaagtct attttcgttt ctttgtaatt
    17641 acgaaaagtc ttgagagata gatgttgtag ccacatgatt atctaccagg gaatcgtgga
    17701 gcttgttggc ttttaggtga tgaagcaggt ttcgatttgt cttttttaac tcccttattc
    17761 atctttttga caagtttagc gatccgttct ttttcaactt tatcagcttg gtattcatct
    17821 tgttcttcag aagtaggttg tgtcaacaag atgtcaatgt tcatgtcagg gatgtcaact
    17881 ttatcgccaa tacgaagttt ttttccacga cgactctcta attccctatt aaagtaaaca
    17941 gaatgttcag agagaaatga tttaatagct cctccgctat gtgtaattcc aagttctttg
    18001 agtagtgctt ggagggtaat aaattcttca aataatttgt attccataat tcacctcaat
    18061 ctttggtatt ataccatatt ttcctaaaaa tagtgagaga gacagagaga aatgtaagcg
    18121 atttttattt caaaagtgtt acagggaaca agaaaatttc aggttttcgt gatataatag
    18181 aagtctgtat ataaggaggt aaatcatgga gttagtgcat ggaatttcaa cacattttat
    18241 ccaatcaaaa aagtttaaaa caaacaaaat taccgtgcgt tttaccgctc cattatccct
    18301 tgatacgatt gcaggtcaca tgttgagtgc aagtatgcta gagactgcta atcagatgta
    18361 ccccacttct caagatttga ggagacactt ggccagtcta tacggtacag atatgtcaac
    18421 caattgtttc agaagagggc aaagccacat tatagaattg acatttacct atgttcgtga
    18481 tgagttttta agtaggaaaa acgtgctaac ctctcagatt ttggaacttg taaaagaaac
    18541 tcttttttca cccgtagtag ttgataatgg gtttgatccg cccttatttg aaattgagaa
    18601 aaaacaattg ctagcaagtt tagcagctga tatggatgat tctttttatt ttgcacataa
    18661 agaattggat aaattgtttt ttcatgatga acgtcttcaa ttggaatata gtgatttacg
    18721 aaatcgtatt ttagctgaaa ctccacaaag ttcttattct tgtttccaag aatttttagc
    18781 caatgatcga atagatttct ttttcctagg tgattttaat gaggttgaaa ttcaaaatgt
    18841 attagaatca tttggcttta aaggtcgaaa aggagatgtg aaggttcagt attgtcaacc
    18901 ttattctaat atccttcagg aaggtatggt tcggaaaaat gtgggacaat ccattttgga
    18961 attaggttat cattaccgtt ctaaatatgg tgatgagcaa catttaccca tgattgtaat
    19021 gaatggttta cttggtggat ttgctcactc taagctcttt acaaatgtcc gtgaaaatgc
    19081 tggattagct tataccattt caagtgagct tgatttattt agtggattct tgaggatgta
    19141 tgctggtatc aatcgagaaa atcgtaacca ggctcgtaaa atgatgaata atcaactgct
    19201 tgatttaaaa aaaggttatt ttacagagtt tgagttaaat cagaccaagg aaatgattcg
    19261 ttggtcgttg ttactttctc aagataatca atcttcattg attgaacgtg cttatcaaaa
    19321 tgccttattt ggaaaatctt cagcagactt taaaagttgg attgcaaagc ttgaacaaat
    19381 tgacaaagat gctatttgta gagtagctaa taatgtgaaa ctacaagcga tttactttat
    19441 ggaaggaata gaatgacaaa ggttgttttt gaagaaaaat actatccagc tgtaaaagaa
    19501 atggtttatc gaactcgttt ggccaacgga ttgacagttg ctcttttgcc taaaaaggaa
    19561 tttaaagagg tttacgggag tgtcactgta cagtttggtt cggtagatac gtttgtcaca
    19621 gaagttgacg gagatgtaaa acaatatcct ggaggaattg ctcattttct tgaacataaa
    19681 ttatttgaga gagaagattc tagtgatttg atgtcggctt ttacgagtct aggtgcagat
    19741 agtaatgcct ttacaagctt tacaaaaaca aactatcttt tttcagcaac ggattgtttt
    19801 ttagaaaatt tagatttact tgatgaattg gtaacatcag cacactttac tgaagcttcc
    19861 attctgacag agcaggatat tattcagcaa gaacgagaaa tgtaccaaga tgatccagat
    19921 tcgtgtttat tcttttcaac tttagcgaat ttgtatcctg gtacaccttt agcaactgat
    19981 atagttggaa gtgaggagtc catgtcccaa atcaatctaa ctaatttgca agaaaatttt
    20041 acaaagtttt acaaacctgt aaacatgtct ctgtttttag ttggtaattt tgatgtggag
    20101 cgagtacagg actattttga aagcaaagaa ctgaaagatt cagattttca ggaagtagca
    20161 agagaaaagt tgtttttaca gcctgtaaag ccaacagata gtatgagaat ggaagtatct
    20221 tctcccaaac tagcgattgg agttagaggt aagcgagaag tttctgaagc ggattgctat
    20281 cgacatcata ttttattaaa attattgttt gcaatgatgt ttggttggac ttcggatcgt
    20341 tttcaaaaat gttatgaatc aggtaaaatt gatgcgtcct tatctctgga agttgaaata
    20401 acaagtcgct ttcattttgt catgttgaca atggatacga aagagccagt tgctttgtct
    20461 catcaattta ggaaggctat tcgtaatttt acaaaggatt tagatattac agaggaacat
    20521 ttagatatta tcaaaagaga gatgtttggc gaatttttca gtagcatgaa ctctcttgaa
    20581 tttattgcaa cgcaatatga tgcttttgaa aatggtgaga caatttttga tttgccgaaa
    20641 attttacagg aaattacttt agaggatgtc cttgatgctg gacatcattt aatagatgat
    20701 ggtgacatag ttgattttac aatattccca tcgtagtaac ctatcataat agacactaga
    20761 aagaagggat gacaagtatg agaaaaaaaa caattggaga ggttttacga ttagctagaa
    20821 tcaatcaggg attgagttta gatgaattgc agaaaaagac agaaatccag ttagatatgt
    20881 tggaagcaat ggaagcagac gatttcgatc aacttccaag tcctttttac acgcgttctt
    20941 tcttgaaaaa atatgcatgg gctgttgagt tagatgacca aattgttttg gatgcttatg
    21001 attctgggag tatgattact tatgaggaag tagatgttga tgaagatgag ttgacaggtc
    21061 gtagacgttc aagtaagaaa aagaagaaaa aaacatcatt tttaccttta ttttatttta
    21121 tcctttttgc tttatcgatt ttaatttttg tgacttatta tgtttggaac tatattcaaa
    21181 ctcaaccaga ggagccttct ctttctaatt acagtgtggt tcaatcaaca agttcaacta
    21241 gctctgttcc ccactcctca agtagtagtt cttctagtat agaatcagct ataagtgtat
    21301 caggcgaagg aaatcatgta gaaatcgctt ataagacaag taaggaaaca gttaaattgc
    21361 aattggcagt ttcagatgtt acaagttggg tcagtgtttc agaaagcgaa cttgagggcg
    21421 gtgtaacctt atcgccaaag aagaaaagtg cagaagcaac agttgcaact aaaagtcctg
    21481 taacaattac gttaggtgtt gtaaaaggtg ttgatttgac agtagataat cagactgttg
    21541 atttatcgaa attaacagct cagactggac aaatcactgt aacctttact aaaaattaag
    21601 gaaaaacgaa tgaaaaaaga acaaattccc aatctcttaa caataggtcg aattctcttt
    21661 atacctattt ttatctttat tttaacgata ggaaattcga tagagagtca tatagttgca
    21721 gctattatct ttgctgttgc cagtattacc gactatttag atggatattt agctcgtaaa
    21781 tggaatgtgg tcagtaattt tggtaaattt gcagatccta tggcggataa gttactagtt
    21841 atgtcggctt ttattatgtt gattgagtta ggtatggctc cggcttggat tgttgcagtg
    21901 attatctgtc gtgagttagc tgtgacaggt ttaaggcttt tattggttga aactggtgga
    21961 acaattttag cagcagcaat gcctggaaaa attaaaactt ttagtcagat gtttgccatt
    22021 attttcttgc tattacattg gactttgctt ggtcaagttc tactttatgt agccttattt
    22081 ttcactatct actctggcta tgactatttc aagggtagtg cctatgtatt taaagggaca
    22141 tttggttcga aatgaaatca ataattgatg taaaaaatct ttcttttcgc tataaagaaa
    22201 atcagaacta ctacgatgtg aaggatatta cgtttcacgt gaaacgtgga gaatggcttt
    22261 cgattgtagg gcataatggt agtggtaaat caacgacggt tcgattaatt gatggcttac
    22321 tggaagcaga atccggagag attgtaattg atggccaacg tttgactgag gaaaatgttt
    22381 ggaatatacg tcgtcaaatc ggtatggttt ttcaaaatcc agacaatcaa tttgttggag
    22441 cgactgttga agatgatgtt gcttttggtt tggaaaatca gggactttct cgtcaagaaa
    22501 tgaaaaagag agtggaagaa gctctggctt tagttggcat gttggacttt aaaaagagag
    22561 agccagcgcg tctatcaggt ggccaaaagc aacgtgtggc cattgcaggt gttgtagccc
    22621 taagaccagt tattttaatc ttagatgaag caacgagtat gttggatcct gaggggcgta
    22681 gagaacttat tgggacagta aaaggaattc gaaaagacta tgatatgacg gtcatttcta
    22741 ttacccatga tttggaagaa gtcgccatga gtgatcgcgt attggtcatg aaaaaagggg
    22801 aaattgaatc aactagtagt ccaagggagc ttttctctcg aaatgattta gatcaaattg
    22861 gattagacga tccttttgct aatcaattaa aaaaatcttt gagccagaat ggctatgatt
    22921 tacctgaaaa ttatttgaca gaaagtgagc tagaggataa gctatgggaa ttgctctaga
    22981 aaatgtgaat tttacatatc aagaaggtac tcccttagct tcagcagctt tgtcggatgt
    23041 ttctttgacg attgaagatg gctcttatac agctttaatt gggcacacag gtagtggtaa
    23101 atcaactatt ttacaactct taaatggttt attggtgcca agtcaaggga gtgtgagggt
    23161 ttttgatacc ttaatcacct cgacttctaa aaataaagat attcgtcaaa ttagaaaaca
    23221 ggttggcttg gtatttcagt ttgctgaaaa tcagattttt gaagaaacgg ttttgaagga
    23281 cgttgctttt ggaccgcaaa attttggagt ttctgaagaa gatgctgtga agactgcgcg
    23341 tgagaaactg gctctggttg gaattgatga atcacttttt gatcgtagtc cgtttgagct
    23401 gtcaggggga caaatgagac gtgttgccat tgcaggcata cttgccatgg agccagctat
    23461 attagtctta gatgagccaa cagctggtct agatcctcta gggagaaaag agttgatgac
    23521 cctgttcaaa aaactccacc agtcagggat gaccatcgtc ttggtaacgc atttgatgga
    23581 tgatgttgct gaatatgcaa atcaagtcta tgtaatggaa aagggacgtt tagtaaaggg
    23641 gggcaaacca agtgatgtct ttcaagacgt tgtttttatg gaagaagttc agttgggagt
    23701 acctaaaatt acggcctttt gtaaacgatt ggctgataga ggcgtgtcat ttaaacgatt
    23761 accgattaag atagaggagt tcaaggagtc gctaaatgga tagtatgatt ttggggcgtt
    23821 atatcccagg ggattcgatt gttcaccgat tggatccacg tagcaaattg cttgctatga
    23881 tgctactgat tttgattgtg ttttgggcta ataacccctt gacgaatctg attcttttta
    23941 tagcgacagg gatatttatt gccttgtcag gagtatctct ttcatttttt attcagggct
    24001 tgaagtctat gtttttcttg attgccttca caactatttt tcaactattt ttcatttcta
    24061 atgggaatgt tttatttgag ttttcgtttg tgagaatcac ggattatgct ttgcaacaag
    24121 ctgggattat tttttgtcgc tttgtattga ttattttctt ttcaactttg ttaaccttaa
    24181 caaccatgcc tttaagtttg gcatcagctg tcgaagcttt attagcacct ttaaagcgtg
    24241 tgaaagttcc agttcatgaa attggattga tgctgtctat gagtttgcgt tttgtcccaa
    24301 ccttgatgga tgatacgact cggattatga atgcacagaa agctcgtgga gtggattttg
    24361 gagaaggaag catcgttcaa aaagtaaagg cgatgattcc cattttgatt cctctttttg
    24421 cgacaagttt aaaacgtgca gattccttgg ctatcgctat ggaagcgcgt ggctatcagg
    24481 gtggaaaagg cagaagtcaa taccgacaat tgaaatggac tctaaaggat acgctgacca
    24541 ttcttgttat tctcgtactt ggttgttgtt tatttttctt aaaatcttag tagctttcag
    24601 gaattgataa aaagttactg taacagtttt tgatataaag gtagggatat gaaccgtttt
    24661 aaaaaatcaa aatatgtcat tattgttttt gtcactgttc tgcttgtgtc agctctctta
    24721 gcgacgactt attcaagtac aattgtgaca aaattaggag atggaatctc attggttgat
    24781 agagttgtac aaaaaccttt tcagtggttt gattctgtca aatcagattt ggctcatttg
    24841 acacgaacat ataatgaaaa tgaaagtttg aagaaacagc tttaccaatt agaagttaaa
    24901 tcaaatgagg tggaaagttt aaagacagaa aatgaacaac tgcgccaatt gcttgatatg
    24961 aagtctaaat tgcaagccac aaagacttta gcagcagatg ttattatgcg ttctccggta
    25021 tcttggaagc aggagttgac cttagatgca ggtagatcaa aaggtgcttc tgagaacatg
    25081 ttagctattg caaatggtgg cttgattggg agtgtttcaa aagtagagga gaactctact
    25141 atagtcaacc ttctgacaaa tacggaaaat gctgataaga tttctgttaa aattcaacat
    25201 ggctctacta caatttatgg aattattatt ggctatgaca aggaaaatga cgttcttaaa
    25261 attagccaat taaatagtaa tagcgatatt agtgcgggag ataaggtgac tactggtgga
    25321 ttaggaaact ttaacgttgt tgatattcct gttggtgaag tggttgccac aacgcatagt
    25381 acagactatt tgacacgaga agtaactgtt aaattgagtg cagatactca taatgtagat
    25441 gtgatagaat tagtggggaa ttcataatga gacagttgaa gcgagttgga gtatttttat
    25501 tgcttccttt ctttgttcta attgacgccc atattagcca gcttctgggc tcatttttcc
    25561 cccatgtaca tttggctagt cattttcttt ttctatttct cttatttgag acgatagaag
    25621 tatcagagta tctctaccta gtctattgtt ttgttatagg cttggtttat gatgtttact
    25681 ttttccatct aatagggatt acaactctct tatttatctt attgggagcc ttccttcata
    25741 aattgaatag tgttattttg ttgaatcgtt ggacaagaat gctagctatg attgtgctga
    25801 cattcctgtt tgaaatgggt agttatcttt tggcttttat ggtagggttg acagtagata
    25861 gcatgtcgat ttttatagtc tatagcttgg taccgacgat gattttaaat tttttatgga
    25921 ttactgtttt tcaatttatt tttgaaaaat attatctata agaacgacat ataaatgtaa
    25981 caaaggcgta atatttatta ggcctttttt tggtatacta gtattgtctt taaaagaagg
    26041 agtatctacg taatatgaag aaaaaaatct tagcgtcact tttattaagt acagtaatgg
    26101 tttctcaagt agctgtttta acaactgcgc atgcagaaac gactgatgac aaaattgctg
    26161 ctcaagataa taaaattagt aacttaacag cacaacaaca agaagcccaa aaacaagttg
    26221 accaaattca ggagcaagta tcagctattc aagctgagca gtctaacttg caagctgaaa
    26281 atgatagatt acaagcagaa tctaagaaac tcgagggtga gattacagaa ctttctaaaa
    26341 acattgtttc tcgtaaccaa tcgttggaaa aacaagctcg tagtgctcaa acaaatggag
    26401 ccgtaactag ctatatcaat accattgtaa actcaaaatc aattacagaa gctatttcac
    26461 gtgttgctgc aatgagtgaa atcgtatctg caaacaacaa aatgttagaa caacaaaagg
    26521 cagataaaaa agctatttct gaaaaacaag tagcaaataa tgatgctatc aatactgtaa
    26581 ttgctaatca acaaaaattg gctgatgatg ctcaagcatt gactacgaaa caggcagaac
    26641 taaaagctgc tgaattaagt cttgctgctg agagagcgac agctgaaggg gaaaaagcaa
    26701 gtctattaga gcaaaaagca gcagctgagg cagaggctcg tgcagctgcg gtagcagaag
    26761 cagcttataa agaaaaacga gctagccaac aacaatcagt acttgcttca gcaaacacta
    26821 acttaacagc tcaagtgcaa gcagtatctg aatctgcagc agcacctgtc cgtgcaaaag
    26881 ttcgtccaac atacagtaca aacgcttcaa gttatccaat tggagaatgt acatggggag
    26941 taaaaacatt ggcaccttgg gctggagact actggggtaa tggagcacag tgggctacaa
    27001 gtgcagcagc agcaggtttc cgtacaggtt caacacctca agttggagca attgcatgtt
    27061 ggaatgatgg tggatatggt cacgtagcgg ttgttacagc tgttgaatca acaacacgta
    27121 tccaagtatc agaatcaaat tatgcaggta atcgtacaat tggaaatcac cgtggatggt
    27181 tcaatccaac aacaacttct gaaggttttg ttacatatat ttatgcagat taatttacag
    27241 agggactcga atagagccct cttttcaggt tttaccgtga caatccctat taaaaattat
    27301 atcaaaatag cttgaaaata ttggaaaagt atggtagaat gaaaattgtc gtgtgaacga
    27361 taatactcat tcttgatgaa ttgtgaagca gttgcccttg ggtcgttttg cgagttgaag
    27421 tcaagaagag gaaaaaaaca aaaaggagaa atactcatgg cagtaatttc aatgaaacaa
    27481 cttcttgagg ctggtgtaca ctttggtcac caaactcgtc gctggaatcc taagatggct
    27541 aagtacatct ttactgaacg taacggaatc cacgttatcg acttgcaaca aactgtaaaa
    27601 tacgctgacc aagcatacga cttcatgcgt gatgcagcag ctaacgatgc agttgtattg
    27661 ttcgttggta ctaagaaaca agcagctgat gcagttgctg aagaagcagt acgttcaggt
    27721 caatacttca tcaaccaccg ttggttgggt ggaactctta caaactgggg aacaatccaa
    27781 aaacgtatcg ctcgtttgaa agaaattaaa cgtatggaag aagatggaac tttcgaagtt
    27841 cttcctaaga aagaagttgc acttcttaac aaacaacgtg cgcgtcttga aaaattcttg
    27901 ggcggtatcg aagatatgcc tcgtatccca gatgtgatgt acgtagttga cccacataaa
    27961 gagcaaatcg ctgttaaaga agctaaaaaa ttgggaatcc cagttgtagc gatggttgac
    28021 accaatactg atccagatga tatcgatgta atcatcccag ctaacgatga cgctatccgt
    28081 gctgttaaat tgatcacagc taaattggct gacgctatta tcgaaggacg tcaaggtgag
    28141 gatgcagtag cagttgaagc agaatttgca gcttcagaaa ctcaagcaga ttcaattgaa
    28201 gaaatcgttg aagttgtaga aggtgacaac gcttaattta tacaaatagt aattacctag
    28261 gagggcgggg cttagcccgg ctctcctatt ttcaaaaaat ataggagaat taaaatggca
    28321 gaaattacag ctaaacttgt aaaagagttg cgtgaaaaat ctggtgccgg tgttatggac
    28381 gctaaaaaag cgcttgtaga aacagacggt gacatcgaaa aagcgattga attgcttcgt
    28441 gaaaaaggta tggctaaggc agctaagaaa gctgaccgtg ttgctgcaga aggtttgact
    28501 ggtgtttatg ttaacggtaa tgttgcagca gttattgaag taaacgctga aactgacttc
    28561 gttgcaaaaa acgctcaatt cgttgaattg gtaaatacta cagctaaagt cattgctgaa
    28621 ggaaaacctg ctaacaatga agaagctctt gctttgataa tgccttcagg tgaaactctt
    28681 gaagctgcat acgtatctgc aacagcaact atcggagaga aaatctcatt ccgtcgcttt
    28741 gcattgattg aaaaaacaga cgcacaacac tttggagcat accaacataa cggtggacgt
    28801 atcggtgtta tttcagttgt tgaaggtgga gacgaagcac ttgctaaaca attgtcaatg
    28861 cacatcgcag cgatgaaacc aacagttctt tcttacaaag aattggatga gcaattcgtt
    28921 aaagatgagt tggcacaatt gaatcacgtt atcgaccaag acaacgaaag ccgtgcaatg
    28981 gttaataaac cagctcttcc acacttgaag tatggatcaa aagctcaatt aactgatgat
    29041 gttattgctc aagctgaagc tgacatcaaa gctgaattgg ctgcagaagg caaaccagaa
    29101 aaaatctggg acaaaattat tccaggtaaa atggatcgct tcatgcttga taacactaaa
    29161 gttgaccaag cttacacact tcttgcacaa gtttacatca tggatgacag caagacagtt
    29221 gaagcatacc ttgaatcagt taacgcttcg gtagttgagt ttgctcgctt tgaagttggt
    29281 gaaggtatcg agaaagctgc aaacgacttc gaagctgaag ttgcagctac aatggcagca
    29341 gccttgaata actaataata gaaaggaagc aatttgcttc cttttttgta tagggcttat
    29401 atttttcctg aaattgtttt tcccccagtc tcactcgatt agaataatta aaacaaaaag
    29461 ccctataata agggctaagt gcatttagga gactatactt caaattcata gtaagcgcgt
    29521 cataacaagg tatctatcct aattccccaa cttccagtat actagataaa aaataattat
    29581 cggaggaaag gtattgtact atgatgattc aactaagtga tttaggtcaa gttcacattg
    29641 tttgtggcaa gacagatatg aggcagggaa tagactcatt agcctatgta gttaaaaccc
    29701 actttgaatt ggattctttc tccggtcaag tctttctctt ttgtggtgga cgtaaagacc
    29761 gctttaaagt cctttactgg gatggtcaag gattttggct actatataaa cgctttgaga
    29821 acggaaaact gacttggcta agtacagaaa aggatgtcaa agctctcaca tctgaacaag
    29881 tagattggct tatgaagggc ttttctatca ctccaaaaat atagtagatt gaaactagaa
    29941 tagtacacct ctgcttctaa aacattgtta gaaatcgatt tgattgtcct gatcgatttg
    30001 tcctgttctt atttcatttt actataaatc catcagaaag ttgtgatttc tattgaaatg
    30061 aggactttct ttttacactc atctgctttc aaaaagcatt ctagtccatc tccgattaac
    30121 gatggacttt atcacctcct tctccagtcc ttgtatgaca tcttccaaag ttcgaaaggc
    30181 tttattctta aatccacgtt tacgaatctc tttccacact tgttcaatgg ggttcatctc
    30241 tggtgtgtat ggaggaataa atgcaaagcc aatattagtc ggaatcttta aggtacttga
    30301 tttatgccat atagcattgt ccataacgag taaaagataa tcatctggat aagcttgtga
    30361 aagctcctat tcctaaagcc cctttagcgc atagctttgg ctcagcttct attatcgctc
    30421 acaccatcca tcagaagttt aatctgaagg tacccaatta tcgccaagaa gaagattggg
    30481 ctaagatggg tttaccaatc acacgcaagg aaatctctaa ttggcatatc aagacgagtc
    30541 aatactattt ggagcccctc tataacctct tgcgagagag actattgact cagcccttac
    30601 ttcatgcgga tgaaacttct tatagggtgc tagagagtga tagtcagctg acttactatt
    30661 ggactttttt gtctgggaaa gctgagaaac aagggattac gctttaccat catgtcctaa
    30721 tcgatttgtt catatcttat ttcaatccat tataaatagt gagaaatatc tatcctatct
    30781 tctagaatgt cttccaaacg tggaaactct cgtaaacaaa gaggttttag aggcttattt
    30841 accatggact aaagttgtac aagaaaagtg caaataagaa atctccagat taggaactat
    30901 ccgtgagttc tctagtctgg agatttttca atatacttcg ttattggacg gttacaattc
    30961 ataaagtgct gtagagagat aacgttcacc gttatctggt gctaggacaa ggactttttt
    31021 acctgtacct aattttttgg caacctcgat ggctccgtag atagctgcag ctgaggaaat
    31081 ccctacaagg aagccttctt ttccaccaat ttcacgtccg agtgcaagag cgtcatctga
    31141 tgttacacga acgataccat cataggcttt agtatcaagt gtatcaggaa taaatccagc
    31201 tgagatacct tgaattttgt gaggaccagg tttttcacca gatagaatag cagattcatc
    31261 tgcttctact gcaaaaactt gaatgttaga attttctgat ttgagtgcat gagaaacacc
    31321 agaaatcgtt ccaccggtac ctactccagc aacaaaggca tctaatccat ctttaccgaa
    31381 agcagctagt atctcagctc ctgttgttct ttcgtgtact tctggattag ctggattgtc
    31441 aaattgaaga ggaaggaaac catcacgttc agcagcgatt tcttgagcct tagcaatagc
    31501 acctttcatt ccctcgctac caggagttag gacgagttca gcaccataag cttggataat
    31561 tttacgtcgt tctacactca tagtttcagg cataacgatg acgactttat accctttagc
    31621 agcacctacc catgaaagtc caataccagt gtttccactt gttgcttcaa caatagtaga
    31681 accaggtttc agaataccat cttgttcagc tttttcaatc atgctaaggg caatacggtc
    31741 ttttacagat gaaccaggat taaatgcttc aagctttata tagacgtctg cagcaccttc
    31801 tggcacgatg ttgttaagtt taacaatcgg tgtttgaccg attaattcag taatgttgtt
    31861 ataaatagac atatgaatac ctctttgtat aagatatctt tagtataacg ctatctatac
    31921 catttgtaaa atatagaaat cctatcgaag cgataggatt tctatatatc atagatcaaa
    31981 gtcattaatt ttcaagtgat tgcgttcagc taattctagt aaataggtgt gaaggaaaac
    32041 gatatcaggt ttcgtttgaa ttgcttcatt ttctagtata ttttggtacg catcttttta
    32101 ttttgctcgc taaagtagtt gtgagaatgt caacgaaacg ctgtattatt cattgtttac
    32161 actaagttta caggaacttc aacctctcgt aaaccttggt cagttaaagt gacttttcca
    32221 ttaaaaaact ccacaagtgc agctttaata gtttcttttt cttccttatc aacataaatc
    32281 atcgtatcga cttgatctgt aaagtttgta tccagctcca tgagatcatg ttctttaagg
    32341 aagttactgt actcttggta ctgagcataa gacatttgaa tagcaatgcc agcctgttct
    32401 tttatttcaa taataccaat ttctttgaca gctaaggcga cactgccggc gtaagcacga
    32461 attagtcctc cagcgcctag tttaatacca ccaaagtagc gtgtcacgac cacacagaca
    32521 ttggtgagat tgtgattttc tagtacccca agcatgggaa caccagcagt accactaggc
    32581 tcaccatcat cacttgtacg tttaatttca ctacgttctc caataataaa ggcagagcag
    32641 ttatgtgtcg ctttgtagtg ttcttttttg atggcagtaa tgaagtcacg agcctcttct
    32701 tcgctataaa cacgcttggc atggcagata aagcgagatt ttttgatttc ttcttggact
    32761 tggccgtcct ctttaattgt cctaaattcc atgatttaat tgtactaaaa aataatctaa
    32821 agtgctagtt tttacgaata aagaagtatg aaagtaaatt tagattatct cggtcgttta
    32881 tttactgaga atgaattaac agaagaagaa cgtcagttgg cggagaaact tccagcaatg
    32941 agaaaggaga aggggaaact tttctgtcaa cgttgtaata gtactattct agaagaatgg
    33001 tatttgccca tcggtgctta ctattgtcga gagtgcttgc tgatgaagcg agtcagaagt
    33061 gatcaaactt tatactattt tccgcaggag gattttccga agcaagatgt tctcaaatgg
    33121 cgcggccaat taactccttt tcaagagaag gtgtcagagg gactgcttca agcagtagac
    33181 aagcaaaagc caaccttagt tcatgcggta acaggagctg gaaagacaga aatgatttat
    33241 caagtagtgg ctaaagtgat caatgcgggt ggtgcagtgt gtttggctag tcctcgcata
    33301 gatgtttgtt tggagctgta caagcgcctg caacaggatt tttcttgcgg gatagctttg
    33361 ctacatggag aatcggaacc ttattttcga acaccactag ttgttgcaac aacccatcag
    33421 ttattgaagt tttatcaagc ttttgatttg ctgatagtgg atgaagtaga tgcttttcct
    33481 tatgttgata atcccacgct ttaccacgct gtcaagaata gtgtaaagga gaatggattg
    33541 agaatctttt taacagcgac ttcgaccaat gagttagata aaaaggtccg tttaggagaa
    33601 ctaaaaagac tgagtttacc gagacggttt catggaaatc cgttgattat tccaaaacca
    33661 atttggttat cggattttaa tcgctactta gacaagaatc gtttgtcacc aaagttaaag
    33721 tcctatattg agaagcagag aaagacagct tatccgttac tcatttttgc ttcagaaatt
    33781 aagaaagggg agcagttaga agaaatctta caggagcaat ttccaaatga gaaaattggc
    33841 tttgtatctt ctgtaacaga ggatcgatta gagcaagtac aagcttttcg agatggagaa
    33901 ctgacaatac ttattagtac gacaatcttg gagcgtggag ttaccttccc ttgtgtggat
    33961 gttttcgtag tagaggccaa tcatcgtttg tttaccaagt ctagtttgat tcagattggt
    34021 ggacgagttg gacgaagcat ggatagaccg acaggagatt tgcttttctt ccatgatggg
    34081 ttaaatgctt caatcaagaa ggcgattaag gaaattcaga tgatgaataa ggaggctggt
    34141 ctatgaagtg cttgttatgt gggcagacta tgaagactgt tttaactttt agtagtctct
    34201 tacttctgag gaatgatgac tcttgtcttt gttcagactg tgattctact tttgaaagaa
    34261 ttggggaaga gaactgtcca aattgtatga aaacagagtt gtcaataaag tgtcaagatt
    34321 gtcaactttg gtgtaaagag ggagttgaag tcagtcatag agcgattttt acttacaatc
    34381 aagctatgaa ggattttttc agtcggtata agtttgatgg agacttcctg ttaagaaaag
    34441 ttttcgcttc atttttaagt gaggagttga aaaagtacaa agagtatcaa tttgttgtaa
    34501 ttcccctaag tcctgataga tatgctaata gaggatttaa tcaggttgag ggcttggtag
    34561 aggcagcagg ctttgagtat ctggatttat tagagaaaag agaagagaga gccagttctt
    34621 ctaaaaatcg ttcagagcgc ttggggacag aacttccttt ctttattaaa agtggagtca
    34681 ctattcctaa aaaaatccta cttatagatg atatctatac tacaggagca actataaatc
    34741 gtgttaagaa actgttggaa gaagctggtg ctaaggatgt aaaaacattt tcccttgtaa
    34801 gatgaggaaa aaatttgcaa aaatagaatg aaagcgttat aataaaatca taaaaacaaa
    34861 aatgtttaga aagaaggtac tcatatgatt aaatatagta tccgtggtga aaacctagaa
    34921 gtaacagaag caattcgtga ttatgtagtt tctaaactcg aaaagatcga aaagtacttc
    34981 caaccagaac aagagttgga tgcccgaatt aacttaaaag tttatcgtga aaaaacggct
    35041 aaagtggaag taacgattcc gcttggatct attactctcc gcgcagaaga tgtatctcaa
    35101 gatatgtatg gttcaattga ccttgtaact gataaaattg aacgtcagat tcgtaaaaat
    35161 aaaacaaaaa tcgagcgtaa aaataaaaat aaggtagcaa ctggtcaatt atttacagat
    35221 gctttggtgg aagattcaaa tgttgtccag tctaaagttg ttcgttcaaa acaaattgat
    35281 ttaaaaccaa tggatttgga agaagcaatt ctacaaatgg atttattggg gcatgatttc
    35341 tttatctatg tggatgttga agatcagaca accaatgtga tttatcgtcg tgaggatggc
    35401 gaaattggtt tgttagaggt taaagaatct taatttcaat atgtgtaaag gtaggtttac
    35461 tgaattgtaa actacctttt tcttataatt gatagaatta ctgattacac ttttaaaaag
    35521 tcgctttttg aggggtatta tggtataatg ggtgccaaga ggttttgaat gaaaaaattt
    35581 tatgtaagtc caatttttcc tattctagta ggattgattg cgtttggagt cttatccact
    35641 ttcattattt ttgttaataa taatctgttg acggttttaa ttttgtttct ttttgtagga
    35701 ggctatgttt ttttatttaa gaaactgaga gtgcattata caaggagtga tgtagaacag
    35761 atacagtatg taaaccacca agcggaagaa agtttgacat ctctattgga acaaatgcct
    35821 gtaggtgtta tgaaattgaa tttatcttct ggagaggttg agtggtttaa tccctatgct
    35881 gaattgattt tgaccaagga agatggtgat tttgatttag aagctgttca aacgattatc
    35941 aaggcttcag taggaaatcc gtctacttat gccaagcttg gtgagaagcg ttatgctgtt
    36001 catatggatg cttcttccgg tgttttgtat tttgtagatg tatccaggga acaagccata
    36061 acagatgaat tggtaacaag tcgaccagtg attgggattg tctctgtgga taattatgat
    36121 gatttggagg atgcaacttc tgagtcagat attagtcaaa tcaatagttt tatagctaat
    36181 tttatatcag agttttcaga aaaacacatg atgttttctc gtcgggtaag tatggatcga
    36241 ttttatctat ttactgacta cacggtgctt gagggcttga tgaatgataa attttctgtt
    36301 attgatgctt tcagagaaga gtcgaaacag agacagttgc ccttgacctt aagtatggga
    36361 ttttcttatg gcgatggaaa tcatgatgag atagggaaag ttgctttgct caatttgaac
    36421 ttggctgaag tacgtggtgg cgaccaggtg gttgttaagg aaaacgacga aacgaaaaat
    36481 ccagtttatt ttggtggtgg gtctgctgct tcaatcaagc gtacacggac tcgtacgcgc
    36541 gctatgatga cagctatttc agataagatt cggagtgtag atcaggtttt tgtagtcggt
    36601 cacaaaaatt tagacatgga tgctttgggc tctgctgtag gtatgcagtt gttcgccagc
    36661 aatgtgattg aaaatagcta tgctctttat gatgaagaac aaatgtctcc agatattgaa
    36721 cgagctgttt cattcataga aaaagaagga gttacgaagt tgttgtctgt taaggatgca
    36781 atggggatgg tgaccaatcg ttctttgttg attcttgtag accattcaaa gacagcctta
    36841 acattatcaa aagaatttta tgatttattt acccaaacca ttgttattga ccaccataga
    36901 agggatcagg attttccaga taatgcggtt attacttata tcgaaagtgg tgcaagtagt
    36961 gccagtgagt tggtaacgga attgattcag ttccagaatt ctaagaaaaa tcgtttgagt
    37021 cgtatgcaag caagtgtctt gatggctggt atgatgttgg atactaaaaa tttcacctcg
    37081 cgagtaacta gtcggacatt tgatgttgct agctatctca gaacgcgcgg aagtgatagt
    37141 attgctatcc aggaaatcgc tgcgacagat tttgaagaat atcgtgaggt caatgaactt
    37201 attttacagg ggcgtaaatt aggttcagat gtactaatag cagaggctaa ggacacgaaa
    37261 tgctatgata cagttgttat tagtaaggca gcagatgcca tgttagccat gtcaggtatt
    37321 gaagcgagtt ttgttcttgc gaagaataca caaggattta tctctatctc agctcgaagt
    37381 cgtagtaaac tgaatgtaca acggattatg gaagagttag gcggtggagg ccactttaat
    37441 ttggcagcag ctcaaattaa agatgtaacc ttgtcagaag caggtgaaaa actgacagaa
    37501 attgtattaa atgaaataaa ggaaaaggag aaagaagaat gaaagtaatc tttttagcag
    37561 atgttaaagg aaaaggtaaa aaaggcgaaa ttaaggaagt accaacaggg tatgcgcaaa
    37621 actttcttat caaaaagaat ctagccaaag aagcgactgc tcaagctgta ggtgaacttc
    37681 gtggtaaaca aaaatcggaa gaaaaagctc acgctgagat gattgcagaa gggaaagcaa
    37741 ttaaagcaca acttgaagca gaagaaactg ttgtagaatt tgttgaaaaa gttggtccag
    37801 atggtcgtac ctttggttct attaccaata agaagattgc agaagaatta caaaagcaat
    37861 ttggaattaa gattgataaa cgtcatattc aagtacaagc tccgattcga gcggttggtt
    37921 tgattgatgt gccagtgaaa atctatcaag atatcacaag tgtaatcaat cttcgtgtga
    37981 aagaaggata agtttacacc ttcttgacaa gattgtaaaa ggaagggaag tctgatggca
    38041 gaagtagaag agttacgagt acaacctcaa gatatcttag ctgagcaatc cgttttaggg
    38101 gctatcttta ttgatgagag taaacttgtt tttgtgcgag aatacattga gtctcgggac
    38161 ttttttaagt atgcccatcg tttgattttc caagccatgg tcgatttatc cgatcgtggt
    38221 gatgccatag atgcaacaac ggttcgtact atccttgata atcaaggtga tttacagaat
    38281 attggtggct tgtcttactt ggttgagatt gtcaattctg tgccaacttc tgctaatgcg
    38341 gagtattatg ctaagattgt tgcagaaaaa gcaatgctac gtcgtttaat tgccaagttg
    38401 acagagtctg tcaaccaagc ttacgaagcg tcacaaccag ctgatgaaat tattgctcag
    38461 gcagaaaaag ggttgattga tgtcagtgaa aatgcaaatc gaagcgggtt taagaacatt
    38521 cgagatgtgt tgaatctcaa ctttggaaat ctggaagctc gctcgcaaca aacgaccgat
    38581 attacaggta ttgcgacagg ttatcgtgat ttggatcata tgacaacagg acttcatgag
    38641 gaggagttga ttatcttagc agctcgtcca gcagttggta agacagcatt tgccttgaat
    38701 atcgctcaga acattgggac taagttggac aaaacggttg ctattttttc actcgaaatg
    38761 ggtgcggaaa gcttggtaga tcgtatgtta gctgcagaag gcttggtgga gtcacattct
    38821 atccgtacag ggcaattgac agatgaggag tggcaaaaat atactattgc tcagggtaat
    38881 ctagctaacg ccagtatcta tatcgatgat acgccaggta ttcggattac agagattcgt
    38941 tctcgttccc gtaaattggc tcaagaaact ggaaatcttg gtttgatttt gatagactat
    39001 ttgcaactta tcacgggaac tggtcgagaa aatcgtcaac aagaagtttc tgaaatttct
    39061 cgtcagttga aaatactagc caaggaattg aaggttccag taatcgctct gagtcagctt
    39121 tctcgtggtg tagaacaacg tcaggacaag agaccagtct tgtctgatat tcgtgaatct
    39181 gggtctattg agcaggacgc tgatatcgta gcttttctct atcgcgatga ctactatgaa
    39241 cgtggtggtg aagaagagga gggtatccca aataataagg tggaagttat tatcgagaaa
    39301 aaccgtagtg gagctcgtgg aacagtggaa ttgattttcc aaaaagaata caataaattt
    39361 tcaagtatct caaagaggga ggcataagat gtcagatgca tttacagatg tagccaagat
    39421 gaaaaaaatc aaagaagaaa tcaaggcaca tgagggacaa gtcgtagaaa tgactttgga
    39481 gaatggtcgt aagcgccaaa aaaatagatt gggtaagcta attgaagttt atccatctct
    39541 atttattgtg gagtttgggg atgtggaagg agataaacaa gttaatgttt acgttgaatc
    39601 ctttacttac tcagatattc ttacagaaaa gaatttgatt cattatcttg actaaagtga
    39661 gaaattttct cactttttct tttttctccg aataatttag gtgaaggcaa tcatcgcttt
    39721 atattatttt tcaaggagga agaatgaaaa ttttaccgtt tatagcaaga ggaacaagtt
    39781 attacttgaa gatgtcagtt aaaaagcttg ttcctttttt agtagtagga ttgatgctag
    39841 cagctggtga tagtgtctat gcctattcca gaggaaatgg atcgattgcg cgtggggatg
    39901 attatcctgc ttattataaa aatgggagcc aggagattga tcagtggcgc atgtattctc
    39961 gtcagtgtac ttcttttgta gcctttcgtt tgagtaatgt caatggtttt gaaattccgg
    40021 cagcttatgg aaatgcgaat gaatggggac atcgtgctcg tcgggaaggt tatcgtgtag
    40081 acaatacacc gacgattggt tctattactt ggtctactgc aggaacttat ggtcatgttg
    40141 cctgggtgtc aaatgtaatg ggagatcaga ttgagattga ggaatataac tatggttata
    40201 cagaatccta taataaacga gttataaaag caaacacgat gacaggattt attcatttta
    40261 aagatttgga tggtggcagt gttgggaata gtcaatcctc aacttcaaca ggcggaactc
    40321 attattttaa gaccaagtct gctattaaaa ctgaacccct agttagtgca actgtgattg
    40381 attactatta tcctggagag aaggttcatt atgatcagat acttgaaaaa gacggctata
    40441 agtggttgag ttatactgcc tataatggaa gctatcgtta tgttcaattg gaggctgtga
    40501 ataaaaatcc tctaggtcat tctgttcttt cttcaacagg aggaactcat tattttaaga
    40561 ccaagtctgc tatcaaaact gaacccctag ttagtgcaac tgtgattgat tactattatc
    40621 ctggagagaa ggttcattat gatcagatac ttgaaaaaga cggctacaag tggttgagtt
    40681 atacggctta taacggaagt cgtcgctata tacagctaga gggagtgact tcttcacaaa
    40741 attatcagaa tcaatcagga aatatctcta gctatggatc caataatagt tcaactgtcg
    40801 gttggaagaa aataaatggt agttggtatc atttcaaatc aaatggttct aaatcaacag
    40861 gatggctgaa agacggttct agctggtatt atttgaaatt atctggtgaa atgcagacag
    40921 gatggttaaa ggagaatggc tcgtggtatt atctgggtag ttcaggggca atgaaaacag
    40981 gctggtacca ggtctctggt aagtggtatt attcttactc ttcaggcgcc ttagctgtta
    41041 atacgacggt ggatggctac agagtaaaca gtgatggaga acgagtatag aaaattggag
    41101 taggagaaat ttcctgctct tttctgtaag cagtttcctt gacatttttc ttattttgcg
    41161 ctatcatata tacatataat atatgggagt ctgtgtacag tctgagagga agtgttaaac
    41221 ttcgaccgca cctgatctgg gtaatgccag cggagggaac gatacttagt ctaattttgc
    41281 accttttcca tgtatggtaa aggtttttct ttttttttaa aaggaaaacg agaagaggag
    41341 gttcttatga aagcaagcat tgccttgcaa gttttacccc tagcacaggg gattgatcgg
    41401 atagctgtta ttgatcaggt cattgcttat ctgcaaactc aagaagtgac gatggtagtg
    41461 acaccatttg aaacggtctt ggaaggggag tttgatgagc ttatgcgcat tctaaaagaa
    41521 gcgctggaag tggcagggca ggaggcagac aatgtctttg ccaatgtcaa aataaatgta
    41581 ggagagattt taagtattga tgagaaactt gaaaagtata ctgagacgac acattagtct
    41641 attgggcttt ctcggagtat tgtcaatctg gcagttagca ggttttctta aacttctccc
    41701 caagtttatc ctgccgacac ctcttgaaat tctccagccc tttgttcgtg acagagaatt
    41761 tctctggcac catagctggg cgaccttgag agtggcttta ctggggctga ttttgggagt
    41821 tttgattgcc tgtcttatgg ctgtgctcat ggatagtttg acttggctca atgacctgat
    41881 ttaccctatg atggtggtca ttcagaccat tccgaccatt gccatagctc ctatcctggt
    41941 cttgtggcta ggttatggga ttttgcccaa gattgtcttg attatcttaa cgacaacctt
    42001 tcccatcatc gttagtattt tggacggttt taggcattgt gacaaggata tgctgacctt
    42061 gtttagtctg atgcgggcca agccttggca aatcctgtgg cattttaaaa tcccggttag
    42121 cctgccttac ttttatgcag gtctgagggt cagtgtctcc tacgccttta tcacaactgt
    42181 ggtatctgag tggttgggag gttttgaagg tcttggtgtt tatatgattc agtctaaaaa
    42241 actgtttcag tatgatacca tgtttgccat tattattctg gtgtcgatta tcagtctttt
    42301 gggtatgaag ctggtcgata tcagtgaaaa atatgtgatt aaatggaaac gttcgtagaa
    42361 ttagaatgtt tctgaaaaag aaaagaggaa atcaaaatga agaaaacatg gaaagtgttt
    42421 ttaacgcttg taacagctct tgtagctgtt gtgcttgtgg cctgtggtca aggaactgct
    42481 tctaaagaca acaaagaggc agaacttaag aaggttgact ttatcctaga ctggacacca
    42541 aataccaacc acacagggct ttatgttgcc aaggaaaaag gttatttcaa agaagctgga
    42601 gtggatgttg atttgaaatt gccaccagaa gaaagttctt ctgacttggt tatcaacgga
    42661 aaggcaccat ttgcagtgta tttccaagac tacatggcta agaaattgga aaaaggagca
    42721 ggaatcactg ccgttgcagc tattgttgaa cacaatacat caggaatcat ctctcgtaaa
    42781 tctgataatg taagcagtcc aaaagacttg gttggtaaga aatatgggac atggaatgac
    42841 ccaactgaac ttgctatgtt gaaaaccttg gtagaatctc aaggtggaga ctttgagaag
    42901 gttgaaaaag taccaaataa cgactcaaac tcaatcacac cgattgccaa tggcgtcttt
    42961 gatactgctt ggatttacta cggttgggat ggtatccttg ctaaatctca aggtgtagat
    43021 gctaacttca tgtacttgaa agactatgtc aaggagtttg actactattc accagttatc
    43081 atcgcaaaca acgactatct gaaagataac aaagaagaag ctcgcaaagt catccaagcc
    43141 atcaaaaaag gctaccaata tgccatggaa catccagaag aagctgcaga tattctcatc
    43201 aagaatgcac ctgaactcaa ggaaaaacgt gactttgtca tcgaatctca aaaatacttg
    43261 tcaaaagaat acgcaagcga caaggaaaaa tggggtcaat ttgacgcagc tcgctggaat
    43321 gctttctata aatgggataa agaaaatggt atccttaaag aagacttgac agacaaaggc
    43381 ttcaccaacg aatttgtgaa ataatgacag aaattagact agagcacgtc agttatgcct
    43441 atggtcagga gaggatttta gaggatatca acctacaggt gacttcaggc gaagtggttt
    43501 ccatcctagg cccaagtggt gttggaaaga ccaccctctt taatctaatc gctgggattt
    43561 tagaagttca gtcagggaga attgtccttg atggtgaaga aaatcccaag gggcgcgtga
    43621 gttatatgtt gcaaaaggat ctgctcttgg agcacaagac ggtgcttgga aatatcattc
    43681 tgcccctctt gattcaaaag gtggataagg cagaaactat ttcccgagcg gataaaattc
    43741 ttgcgacctt ccagctgaca gctgtaagag acaagtatcc tcatgaactt agcggtggga
    43801 tgcgccagcg tgtagcctta ctccggacct acctttttgg gcataagctc tttctcttag
    43861 atgaggcctt tagcgccttg gatgagatga caaagatgga actccacgct tggtatcttg
    43921 agattcacaa gcagttgcag ctaacaaccc tgatcatcac gcatagtatt gaggaggccc
    43981 tcaatctcag cgaccgcatc tatatcttga aaaatcgccc tgggcagatt gtttcagaaa
    44041 ttaaactaga ttggtctgaa gatgaggaca aggaagtcca aaagattgcc tacaaacgtc
    44101 aaatcttggc agaattaggc ttagataagt agaaaaatag ggagttggtg aagattatcc
    44161 tttaccagcg ccctttttct tttaaaaatg agaaaatttc ggtataatag tcaaacaagg
    44221 tcaaggttta aagagagagg tgggtttgtt atgagattta aaaatacatc ggatcatatt
    44281 gaggcctaca tcaaggcgat tttagatcaa tctggtatcg tggagttgca acggagtcag
    44341 ttggcagata cctttcaggt tgttcctagt cagattaact acgtgatcaa gacacgcttt
    44401 acggaaagta gaggctactt ggttgaaagt aagcgtggtg gcggaggcta cattcgtata
    44461 ggacggattg agttttctag tcatcatgaa atgctccggg agctgcttta ttcgattggt
    44521 gagcgagtca gtcaagaaat ttatgaggat attctccagc ttttggttga gcaggaattg
    44581 atgaccaagc aggagatgaa tttgctagta tcagtagctt tggatcgcgt tttaggagaa
    44641 gaagctccag ttgttcgagc aaacatgcta cgtcaggtca tacaagaggt agatagaaaa
    44701 gggaagtaag atgaactatt caaaagcatt gaatgaatgt atcgaaagtg cctacatggt
    44761 tgctggacat tttggagctc gttatctaga gtcgtggcac ttgttgattg ccatgtctaa
    44821 tcacagttat agtgtagcag gggcaacttt aaatgattat ccgtatgaga tggaccgttt
    44881 agaagaggtg gctttggaac tgactgaaac ggactatagc caggatgaaa cctttacgga
    44941 attgccgttc tctcgtcgtt tgcaggttct ttttgacgaa gcagagtatg tagcgtcagt
    45001 ggtccatgct aaggtgctag ggacagagca cgtcctctat gcgattttgc atgatggcaa
    45061 tgccttggcg actcgtatct tggagagggc tggtttttct tatgaagaca agaaagatca
    45121 ggtcaagatt gctgctcttc gtcgaaattt agaagaacgg gcaggctgga ctcgtgaaga
    45181 tctcaaggct ttacgccaac gccatcgtac agtagctgac aagcaaaatt ctatggccaa
    45241 tatgatgggc atgccgcaga ctcctagtgg tggtctcgag gactatacgc atgatttgac
    45301 agagcaagcg cgttctggca agttagaacc agtcatcggt cgggacaagg aaatctcacg
    45361 tatgattcaa atcttgagcc ggaagactaa gaacaaccct gtcttggttg gggatgctgg
    45421 tgtcgggaaa acagctctgg cgcttggtct tgctcagcgt attgctagtg gtgacgtgtc
    45481 tgcggaaatg gctaagatgc gcgtgttaga acttgatttg atgaatgtcg ttgcagggac
    45541 acgcttccgt ggtgactttg aagaacgcat gaataatatc atcaaggata ttgaagaaga
    45601 tggccaagtc atcctcttta tcgatgaact ccacaccatc atgggttctg gtagcgggat
    45661 tgattcgact ctggatgcgg ccaatatctt gaaaccagcc ttggcgcgtg gaactttgag
    45721 aacggttggt gccaccactc aggaagaata tcaaaaacat atcgaaaaag atgcggctct
    45781 ttctcgtcgt ttcgctaaag tgacgattga agaaccaagt gtggcagata gtatgactat
    45841 tttacaaggt ttgaaggcga cttatgagaa acatcaccgt gtacaaatca cagatgaagc
    45901 ggttgaaaca gcggttaaga tggctcatcg ttatttaacc agtcgtcact tgccagactc
    45961 tgctatcgac ctcttggacg aagcagcagc aacagtgcaa aataaggcaa agtatgtaaa
    46021 agcagacgat tcagatttga gtccagctga caaggccctg atggatggca agtggaaaca
    46081 ggcagcccag ctaatcgcaa aagaagagga agtacctgtc tacaaagact tggtgacaga
    46141 gtctgatatt ttgaccacct tgagtcgctt gtcaggaatc ccagttcaaa aactgactca
    46201 gactgacgct aagaaatatc taaatcttga agcagaactc cataaacggg ttatcggtca
    46261 agatcaagct gtttcaagta ttagtcgtgc gattcgccgt aatcagtcag gaattcgcag
    46321 tcacaagcgt ccgatcggtt cctttatgtt cctaggaccc acaggtgtcg gtaagaccga
    46381 gttggccaag gctttggcag aagttctctt tgatgacgaa tcagccctta tccgctttga
    46441 tatgagtgag tatatggaga aattcgcagc cagccgtcta aatggagctc ctccaggcta
    46501 tgtgggttac gaagaaggtg gggagttgac agagaaggtt cgcaataaac cctattccgt
    46561 tctcctcttt gatgaggtag agaaggctca cccagatatc tttaatgttc tcttgcaggt
    46621 tctggatgac ggtgtcttga cagatagcaa gggacgcaag gtcgattttt caaataccat
    46681 tatcattatg acatcgaacc taggtgcgac tgcccttcgt gatgataaga ctgttggttt
    46741 tggggctaag gatattcgtt ttgaccagga aaatatggaa aaacgcatgt ttgaagaact
    46801 gaaaaaagct tatagaccgg aattcatcaa ccgtattgat gagaaggtgg tcttccatag
    46861 cctatctagt gaccatatgc aggaagtggt gaagattatg gtcaagcctt tagtggcaag
    46921 tttggctgaa aaaggcattg acttgaaatt acaagcttca gctctgaaat tgttagcaaa
    46981 tcaaggatat gacccagaga tgggagctcg cccacttcgc agaaccctgc aaacagaagt
    47041 ggaggacaag ttggcagaac ttcttctcaa gggagattta gtggcaggca gcacacttaa
    47101 gattggtgtc aaagcaggcc agttaaaatt tgatattgca taaaagaata aaagtaccag
    47161 catctgacca taagtcacag tggagtgaaa ctcaatgaaa atcaaagagc aaactaggca
    47221 gctagccgca ggttgctcaa aacactggtt tgaggttgca gatagagctg acgtggtttg
    47281 aagagatttt cgaagagtat aagctgcaag atgaatgatt ttcttgtatt gacgttgttg
    47341 ttgacaaaaa gtagcggata aatgaaatcc attccattat catagatgat aggctggtag
    47401 gaaattttca aatagcatac aggaaataga tgtatggagt tctggtagta gaaagggaga
    47461 gagatgaaca ttttagttgc agatgacgag gaaatgatta gagaaggaat tgcagcattt
    47521 ctgacagaag agggttatca tgtcattatg gctaaggatg gacaagaggt cttggaaaaa
    47581 tttcaagatc tccctatcca tctcatggta ctggatttaa tgatgcctag gaagagtggt
    47641 tttgaagtgt taaaagaaat caatcaaaag cacgatattc ctgtcatcgt cttgagtgct
    47701 ctgggagatg aaactactca gtcacaggta tttgatctct atgctgatga tcatgtgaca
    47761 aaaccttttt ctttggtact gcttgtcaag cgtattaagg cgcttatcag acgttactac
    47821 gtcatagagg atctttggcg atatcaggat gtaacagtgg attttacctc ttacaaagca
    47881 cattataaaa atgaagaaat tgatctcaaa ccaaaggaat tactggtact aaagtgtttg
    47941 attcagcata aaaatcaagt tttaagtaga gagcagatat tggaagaaat ttcaaaagat
    48001 gtagctgatt taccttgtga tagggtcgtt gatgtctata ttcgtactct tcgcaaaaaa
    48061 ttagctttag attgtatcgt gactgtgaaa aatgttgggt ataagattag cttatgataa
    48121 aaaatcctaa attattaacc aagtcttttt taagaagttt tgcaattcta ggtggtgttg
    48181 gtctagtcat tcatatagct atttatttga cctttccttt ttattatatt caactggagg
    48241 gggaaaagtt taatgagagc gcaagagtgt ttacggagta tttaaagact aagacatctg
    48301 atgaaattcc aagcttactc cagtcttatt caaagtcctt gaccatatct gctcacctta
    48361 aaagagatat tgtagataag cggctccctc ttgtgcatga cttggatatt aaagatggaa
    48421 agctattaaa ttatatcgtg atgttagata tgtctgttag tacagcagat ggtaaacagg
    48481 taaccgtgca atttgttcac ggggtggatg tctacaaaga agcaaagaat attttgcttt
    48541 tgtatctccc atatacattt ttggttacaa ttgctttttc ctttgttttt tcttattttt
    48601 atactaaacg cttgctcaat cctctttttt acatttcaga agtgactagt aaaatgcaag
    48661 atttggatga caatattcgt tttgatgaaa gtaggaaaga tgaagttggt gaagttggaa
    48721 aacagattaa tggtatgtat gagcacttgt tgaaggttat tcatgagttg gaaagtcgta
    48781 atgagcaaat tgtaaaattg caaaatcaaa aggtttcctt tgtccgtgga gcatcacatg
    48841 agttgaaaac ccctttagcc agtcttagaa ttatcctaga gaatatgcag cataatattg
    48901 gagattacaa agatcatcca aaatatattg caaagagtat aaataagatt gaccagatga
    48961 gccacttatt agaagaagta ctggagtctt ctaaattcca agagtggaca gagtgtcgtg
    49021 agaccttgac tgttaagcca gttttagtag atattttatc acgttatcaa gaattagctc
    49081 attcaatagg tgttacaatt gaaaatcaat tgacagatgc taccagggtc gtcatgagtc
    49141 ttagggcatt ggataaggtt ttgacaaacc tgattagtaa tgcaattaaa tattcagata
    49201 aaaatgggcg cgtaatcata tccgagcaag atggctatct ctctatcaaa aatacatgtg
    49261 cgcctctaag tgaccaagaa ctagaacatt tatttgatat attctatcat tctcaaatcg
    49321 tgacagataa ggatgaaagt tccggtttgg gtctttacat tgtgaataat attttagaaa
    49381 gctatcaaat ggattatagt tttctccctt atgaacacgg tatggaattt aagattagct
    49441 tgtagacaga ttagtttttt attaaagttc atatagggtt aacataagtg tgttattctt
    49501 tgtgtagata aaagaaagga tactaatatg gtattagcga ttattttagt aacattcttt
    49561 attcgattga tttttttaaa gcgttcgata gagaatgaga aacgaatcct tagcaatggc
    49621 gggaaagaat ttggagttga gaatacaaaa cgattaacta tggctcatat tgttttttat
    49681 ctctcttgct tggttgaggc aatggtgcac aagacaattt ttgatggcat gggcatggtt
    49741 ggtttagtct tgcttatttt ttctatgctg atgttaatgt tggtgattca cttgttggga
    49801 gatatttgga cagtgaagct tatgcttgtc aataatcaca aatatgtaga tcatatcttg
    49861 tttaggacag taaaacatcc taattacttt ttaaatattc ttcctgagtt gattggcttg
    49921 accttgttga gtcatgctta tgtgactttt gttttagttt ttccagttta tgcagttatt
    49981 ttgtatcgac gaatagctga agaggaaaag ctattacatg aagttataat cccaaatgga
    50041 agcataaaga gataaataca aaattcgatt tatatacagt tcatattgaa gtaatatagt
    50101 aatagacttc atgcgaaaca aaatatggta caatagttct atgaattatg aagcaaggtt
    50161 gagaatattt ttgccaaagt aaaaacgttt aaaatgtttt caacaaccta tcgaaatcat
    50221 cgtaaacgct tcggattacg aatgaatttg attgctggca ttatcaatca tgaactagga
    50281 ttctagtttt gcaggaagtc taatgttaag aaaaatattg gagaaaataa acatgtttgc
    50341 atcaaaaagc gaaaaaaaag tacattattc aattcgtaaa tttagtattg gagtagctag
    50401 tgtagctgtt gccagtcttt ttatgggaag tgtggttcat gcagaagggg ttagaagtgg
    50461 ggatacccct aaggttacat ctagtgggga tgaagtcgag tcgcatctaa aaaaaatatt
    50521 gagtgagatc caaacacaat tagatagaaa acgacatgcc aaaactgtag cgctaattaa
    50581 caagttgcaa gacattaaga gaacgtattc gtataaatta aatgttttag aagagaagcc
    50641 gaaagctgag ttgacgtcaa aaacaaaaga agagttaacc gcagcttttg agcagtttaa
    50701 aaaagataca ttaccaacag aaccaggaaa aaaggtagca gaagctaaga agaaggttga
    50761 agaagctaag aaaaaagcca aggctcaaaa agaagaagat taccgtaact acccaaccat
    50821 tacttacaaa acgcttgaac ttgaaattgc tgagttcgat gtgaaagtta aagaagcgga
    50881 gcttgaacta gtaaaaaagg aagctgacga atctcgaaat gagggcacaa ttaaccaagc
    50941 aaaagcgaaa gttgagagtg aaaaagctga ggctacaagg ttaaaaaaaa tcaagacaga
    51001 tcgtgaaaaa gcagaagaag aagctaaacg aagagcagat gctaaagagc aagatgaatc
    51061 aaagaggcga aagagtcggg taaaacgagg agatcttgga gagcaagcaa cacctgataa
    51121 aaaagaaaat gatgcgaagt cttcagattc tagcgtaggt gaagaaactc ttccaagccc
    51181 atccctgaaa ccaggaaaaa aggtagcaga agctgagaag aaggttgaag aagctgataa
    51241 aaaagccaag gctcaaaaag aagaagatcg ccgtaactac ccaaccaata cttacaaaac
    51301 gcttgaactt gaaattgctg agtccgatgt gaaagttaaa gaagcggagc ttgaactagt
    51361 aaaagaggaa gctaaggaat ctcaaaacga ggaaaaaatt aagcaagcaa aagcgaaagt
    51421 tgagagtaaa aaagctgagg ctacaaggtt agaaaaaatc aagacagatc gtaaaaaagc
    51481 agaagaagaa gctaaacgaa aagcagcaga agaagataaa gttaaagaaa aaccagctga
    51541 acaaccacaa ccagcgccgg ctcctcaacc agaaaaacca actgaagagc ctgagaatcc
    51601 agctccagct ccaaaaccag agaagccagc tgaacaacca aaagcagaaa aaccagctga
    51661 tcaacaagct gaagaagact atgctcgtag atcagaagaa gaatataatc gcttgactca
    51721 acagcaaccg ccaaaaattg aaaaaccagc tccagcacca caaccagagc aaccagctcc
    51781 agcaccaaaa acaggctgga aacaagaaaa cggtatgtgg tacttctaca atactgatgg
    51841 ttcaatggca acaggatggc tccaaaacaa tggttcatgg tactacctca acagcaatgg
    51901 cgctatggcg acaggatggc tccaaaacaa tggttcatgg tactatctaa acgctaatgg
    51961 ttcaatggca acaggatggc tccaaaacaa tggttcatgg tactacctca acgctaatgg
    52021 ttcaatggcg acaggatggc tccaatacaa tggttcatgg tactacctca acgctaatgg
    52081 tgatatggcg acaggatggt tccaatacaa tggttcatgg tactacctaa acgctaatgg
    52141 tgatatggcg acaggatggc tccaatacaa tggttcatgg tactacctca acagcaatgg
    52201 tgctatggta acaggatggc tccaaaacaa tggctcatgg tactacctca acgctaacgg
    52261 ttcaatggca acagattggg tgaaagatgg agatacctgg tactatcttg aagcatcagg
    52321 tgctatgaaa gcaagccaat ggttcaaagt atcagataaa tggtactatg tcaatggctc
    52381 aggtgccctt gcagtcaaca caactgtaga tagctataga gtcaatgcca atggtgaatg
    52441 ggtaaactaa acctaatata actagttaat actgacttcc tgtaagaact ctttaaagta
    52501 ttccctacaa ataccatatc ctttcagtag ataatatacc cttgtaggaa gtttagatta
    52561 aaaaataact ctgtaatctc tagccggatt tatagcgcta gagactacgg agtttttttg
    52621 atgaggaaag aatggcggca ctcaagagac tctttaagag agttacgggt tttaaactat
    52681 taagccttct ccaattgcaa gagagcttca atctctgcca gggtgctagc ttgcgaaatg
    52741 gctccacgga gtttggcagc gccagatgtt ccacggaggt agtgaggagc gaggccacgg
    52801 aattcacgaa ctgcgacgtt ttctcctttg aggttaatca atcgtttcaa gtgttcgtag
    52861 gcgatcttca tcttgtcttc aaaggtcaaa tcaggtagga tttctcctgt ttcaaagtaa
    52921 tggttgattt ggttgaagag gtaaggattt cccatggcag ctcggccaat catgactgcg
    52981 tcagcaccaa cttcttcgat gcgttgcttg gcttcttgga cagtacggat atcaccgttg
    53041 gcgatgaatg gaatcttggt tagagcttgg gcaaccttgt aaagggtctc aaggtctgcg
    53101 tggccagtat acatttgttc acgggtacgg ccatgcatgg cgagggcaga aacacctgca
    53161 gcctcagcag cgagggcatt ttctactgcc agagatgggt ccgcccagcc ggtacgcatt
    53221 ttgacagtaa gtgggatatc aaggacagac tggaccttgt tgatgataga gtagatcttg
    53281 tcaggatcct tgagccacat agcaccagct tcgttcttca cgattttgtt gacagggcag
    53341 cccatgttga tatcgacgat atcggtctta gtgttttctt ggataaattc tgctgcgcgt
    53401 gctaggctgt cttcatcgct accaaaaagt tggatagaga cagggttttc gccctcatcg
    53461 atatgaagca tgtgcagggt tttttcgttg ttgtattgga ttcccttgtc agagaccatt
    53521 tccattacaa cgagtccagc tccgagctct tttgcgatgg tacgaaaggc tgagttggtc
    53581 acgccagcca taggcgctaa aacggtacga ttgggaatct caacattgcc aatcataaaa
    53641 ggtgtattaa gatttgtcac gaatgagttc ctccaggtcc ttttcatcaa agttgtaagt
    53701 agtttggcag aattgacaag tgatttctac cccgtggtct tcctctttca tttcctgtaa
    53761 gtctgagctt ggaaggctgg caagagcgtt cataaagcgt tcatggctac agtcacattg
    53821 gaaacggatt tcttcttcag aaagacgctt gtaggcttcg tccccgtaga tagccttgag
    53881 gagggcttcg atatggtcgt cgctttcgag aagagtagag atagctggca tttcttggat
    53941 gcgtttttca aagcgagcaa tctcttcttt cttggctcct ggcaagactt gaactaggaa
    54001 accacctgca atcttgacct tgtcttcctc gtccaaaagg acattgaggc cgaccgctga
    54061 aggcgtttgt tggctttcag taaggtaaaa ggcaaggtct tcaccgattt ctccagagat
    54121 gaggggagtt atagagttgt aaggatttcc agtaccgtag tctgtgataa cgaggaattg
    54181 accatttcca acaaaaggtc cgactaggac ttcaccagtc gcagtctttt tgatgtcaac
    54241 accaggattt tgaacgtagc ctttgacgtt ccccttggta tcagcgacgg tgataatagc
    54301 acctagagag ctagatccca acaccttaac tgtaagtttg gtatttcctt tttcattggc
    54361 tgcgagaatc tggctagcga taagagttcg accaagcgct acagttgagc tagcttgggt
    54421 ttgatgtttt tcttgagcag tgcggacggt ttcagtgcta tcaaggacaa aagcacgaaa
    54481 ggctccgctt tctgatatag ttttaataat tttatccata gctactattt tagcataaaa
    54541 atgcccaaag ggggagccgt gtgtttactg attttcagga taatggacca ggaaatcagc
    54601 atgaaaataa aaagagaaac agattatttc agcatttgta agatttatgc tatgcttaag
    54661 gtagaaaatg aaagggataa caaatgtatt taggagattt gatggagaaa gccgagtgtg
    54721 gtcaattttc aatcctttcc tttctattac aagagtctca gacgaccgtc aaggctgtaa
    54781 tggaagaaac aggattttca aaagcaaccc taaccaaata tgtcaccctg ctcaatgaca
    54841 aggctttgga tagtggctta gaactgacta ttcactcaga agatgaaaat ctgcgtctgt
    54901 ctatcggtgc agctaccaag gggagagata ttcggagctt gtttttggag agtgctgtta
    54961 aataccagat tttggtttat cttctctacc accaacagtt tttagcccat cagctggctc
    55021 aagaattggt gattagcgag gctacgcttg gtcgtcactt ggctggttta aatcagattt
    55081 tgtcagaatt tgatttatcc atccaaaatg gacgttggcg aggtccagag catcagattc
    55141 gctatttcta tttctgtctt ttccgaaagg tctggtcgag tcaggaatgg gaaggtcaca
    55201 tgcagaaacc agagagaaaa caggagattg ccaatttaga ggaaatctgc ggtgcaagtt
    55261 tgtctgtggg gcagaaattg gacttggttc tctgggctca catcagtcaa caacgtcttc
    55321 gggtcaatgc ttgtcagttt caagtcatag aagagaaaat gcgagggtat tttgacaata
    55381 tcttttatct tcgtttgctg agaaaggttc cgtccttttt tgctgggcaa catattccac
    55441 taggagttga ggatggtgag atgatgatat tcttctcttt tctcctatct catcgcattc
    55501 ttcctcttca tactatggag tatattcttg gttttggagg gcagttggca gatttactga
    55561 cgcaattgat tcaagaaatg aagaaggagg aactattggg ggattataca gaggaccatg
    55621 tcacctatga actcagtcag ctttgtgctc aagtctatct ctataagggc tatattttac
    55681 aggatcgtta caagtaccag ttagagaatc gtcatccata tttactgatg gaacatgatt
    55741 ttaaagagac agcagaggag atttttcatg ctctacctgc ttttcaacag gggacagatt
    55801 tagataagaa gattctctgg gaatggctcc agttaatcga atatatggct gaaaacggtg
    55861 gccagcatat gcggattggt ctggatttga catctggttt tcttgtcttt tcaaggatgg
    55921 cagccatttt gaaacggtat ttagaataca atcgttttat taccattgaa gcttatgacc
    55981 ctagtcggca ttatgatttg ctggttacca ataacccgat tcataagaag gaacagaccc
    56041 cagtctatta tttaaaaaat gacttggata tggaggattt ggcagggatt cgtcagttat
    56101 tattcactta aaaggcttgg ttgttccagg tcttttttgt gaaattcaca caatctcctc
    56161 acgttttttt aaaaattaaa aaaagttgat aaacaagaaa gcgctttatt ttgtatacta
    56221 gtaagtgtaa agaggaaaca cctcaagatc tttatcagga ggacagtaca tgtcacaaga
    56281 aaaatacatc atggccattg accagggaac tacaagttct cgtgccatca ttttcaacaa
    56341 aaaaggggaa aaggttagct cgagtcaaaa agagtttacc cagattttcc ctcaggcagg
    56401 ttgggttgag cacaatgcca atgaaatttg gaactctgtt cagtcagtta ttgcgggtgc
    56461 tttcattgaa agtggtgtca agccaaatca aatcgaggca atcgggatta ccaaccaacg
    56521 tgaaacaacg gttgtctggg ataagaaaac aggacttcct atctacaatg ctatcgtttg
    56581 gcagtcacgc cagacagcac ctttggctga gcaactaaaa agccaaggtt atgtggaaaa
    56641 attccatgaa aagactggtt tgattattga tgcttacttc tctgctacca aggttcgttg
    56701 gattttggat catgtagaag gtgctcaaga gcgagcagaa aaaggggaat tgctctttgg
    56761 tactatcgat acttggttgg tttggaaatt gactgacggt gcggctcacg tgactgacta
    56821 ctcaaatgca gctcgtacca tgctttataa cattaaagaa ctcaaatggg atgatgagat
    56881 tttggaaatc cttaacattc cgaaggctat acttccagaa gttcgttcta actccgaaat
    56941 ctacggcaag acagctccat tccatttcta cggtggagag gtgccaatct caggtatggc
    57001 tggggaccaa caagcagccc tctttggaca gttggctttt gagccaggta tggttaagaa
    57061 tacttatgga acaggctctt tcatcatcat gaatactggg gaagagatgc agttgtctga
    57121 aaacaacctc ttgacaacca ttggttacgg aatcaacggt aaggtttatt atgccttgga
    57181 aggttctatc ttcatcgcag gaagtgctat tcagtggctt cgtgacggtc ttcgcatggt
    57241 tgaaaattca ccagaatctg aaaaatacgc tcgtgattct cacaacaacg atgaagttta
    57301 tgtcgttcca gcctttacag gtctaggcgc tccatactgg aaccaaaatg ctcgtggttc
    57361 cgtctttggt ttgactcgtg gaacaagcaa agaagacttt atcaaggcga ctttgcaatc
    57421 tattgcttat caagtgcgtg acatcatcga caccatgcaa gtggatactc agaccgccat
    57481 tcaagtactg aaggtggatg gtggtgcagc catgaacaac ttcctcatgc agttccaggc
    57541 ggatatttta ggcattgata ttgcacgtgc taaaaacttg gaaacaacag ctctaggagc
    57601 ggccttccta gcaggtttgt cagtagggta ctggaaagac ttggacgagt tgaaactctt
    57661 gaacgagaca ggagaactct ttgagccatc tatgaacgaa tctcgcaagg aacaactcta
    57721 taagggctgg aagaaggctg tgaaagcaac tcaagtcttt gcggaaatcg atgactaata
    57781 ctcaatgaaa atcaaagagc aaactaggaa gctagccgca agctgtactt gagtacggta
    57841 aggcgacgct gacgtggttt gaagagattt tcgaagagta taatactggc agaataaagc
    57901 gatttagtta gaaagtgtgt aaatatggaa ttttcaaaga aaacacgtga attgtcaatt
    57961 aaaaaaatgc aggaacgcac cctggacctc ttgattatcg gtggaggaat cacaggagct
    58021 ggtgtagcct tgcaggcggc agctagcggt cttgagactg gtttgattga aatgcaagac
    58081 tttgcagaag gaacatctag tcgttcaaca aaattggttc acggaggact tcgttacctc
    58141 aaacaatttg acgtagaagt ggtctcagat acggtttctg aacgtgcagt ggttcaacaa
    58201 atcgctccac acattccaaa accagaccca atgctcttac cagtttacga tgaagatgga
    58261 gcaaccttta gcctcttccg tcttaaagta gccatggact tgtacgatct cttggcaggt
    58321 gttagcaaca caccaactgc gaacaaggtt ttgagcaaga aagaagtctt ggaacgccag
    58381 ccaaacttga agaaggaagg cttggtagga ggtggagtgt atcttgactt ccgtaacaac
    58441 gatgcgcgtc tcgtgattga aaacatcaaa cgtgccaacc aagacggtgc cctcattgcc
    58501 aaccacgtga aggcagaagg cttcctcttt gacgaaagtg gcaagattac aggtgttgta
    58561 gctcgtaatc ttttaacaga ccaagtattt gaaatcaagg cccgtctggt tattaataca
    58621 acaggtcctt ggagtgataa agtacgtaat ttgtctaata agggaacgca attctcacaa
    58681 atgcgcccaa ctaagggagt tcacttggta gtggattcaa gcaaaattaa ggtttcacag
    58741 ccagtttact ttgacacagg tttgggtgac ggtcgtatgg tctttgttct cccacgtgaa
    58801 aacaagactt actttggtac aactgataca gactacacag gtgatttgga gcatccaaaa
    58861 gtaactcaag aagatgtaga ttatctactt ggcattgtca acaaccgctt tccagaatcc
    58921 aacatcacca ttgatgatat cgaaagcagc tgggcaggtc ttcgtccatt gattgcaggg
    58981 aacagtgcct ctgactataa tggtggaaat aacggtacca tcagtgatga aagctttgac
    59041 aacttgattg cgactgttga atcttatctc tccaaagaaa aaacacgtga agatgttgag
    59101 tctgctgtca gcaagcttga aagtagcaca tctgagaaat atttggatcc atctgcagtt
    59161 tcacgtggtt cgagcttgga ccgagatgat aatggcctct tgacccttgc tggtggtaaa
    59221 atcacagact accgtaagat ggctgaaggt gctatggagc gcgtggttga catcctcaaa
    59281 gcagaatttg accgtagctt taaattgatc aattctaaaa cttaccctgt ttcaggtgga
    59341 gaattgaacc cagcaaatgt ggattcagaa atcgaagcct ttgcgcaact tggagtttca
    59401 cgtggtttgg atagcaagga agctcattac ctagcaaatc tttatggttc aaatgcaccg
    59461 aaggtctttg cacttgctca cagcttggaa caagcgccag gtcttagctt ggcagacacc
    59521 ttgtcccttc actatgcaat gcgcaatgag ttgactctta gcccagttga cttccttctt
    59581 cgtcgtacca atcacatgct ctttatgcgt gatagcttgg atagtatcgt tgagccaatt
    59641 ttggatgaaa tgggacgatt ctatgactgg acagaagaag aaaaagcaac ttaccgtgct
    59701 gatgtcgaag cagctctcgc taacaacgat ttagcagaat taaaaaatta agaaaaaata
    59761 aaagaggtgg agggcagcat tccttgtcgc ccgtcccttc tttttaatgg agacagaaag
    59821 atgatgaatg aattatttgg agaatttcta gggactttaa tcctgattct tctaggaaat
    59881 ggtgttgttg caggtgtggt tcttcctaaa accaagagca atagctcagg ttggattgtg
    59941 attactatgg gttgggggat tgcagttgcg gttgcagtct ttgtatctgg caagctcagt
    60001 ccagctcatt taaacccagc tgtgaccatc ggtgtggcct taaaaggtgg tttgccttgg
    60061 gcttccgttt tgccttatat cttagcccag ttcgcagggg ccatgctggg tcagattttg
    60121 gtttggttgc aattcaaacc tcactatgag gcagaagaaa atgcaggcaa tatcctggca
    60181 accttcagta ctggaccagc catcaaggat actgtatcaa acttgattag cgaaatcctt
    60241 ggaacttttg ttttggtgtt gacaatcttt gctttgggtc tttacgactt tcaggcaggt
    60301 atcggaacct ttgcagtggg aactttgatt gtcggtatcg gtctatcact aggtgggaca
    60361 acaggttatg ccttgaaccc agctcgtgac cttggacctc gtatcatgca cagcatcttg
    60421 ccaattccaa acaagggaga cggagactgg tcttacgctt ggattcctgt tgtaggccct
    60481 gttatcggag cagccttggc agtgcttgta ttctcacttt tctagtttat actcttcgaa
    60541 aatcaaattc aaaccacgtc agcgtcgcct taccgtactc aagtacagct tgcggctagc
    60601 ttcctagttt gctctttgat tttcattgag tattagaaaa caattatgtt gatagagctt
    60661 gggcaagagc ccaatttcag caaaaaatga agtaaatctt ctcataataa aacgcatcat
    60721 atcaagcacg aaaattccac gaggtcaact acagtcagaa agctgaacaa caagccaaaa
    60781 cgcccaaaaa aggcggcaaa aagcaagcac ctgcaagcaa cgtgccgaaa tggtcaaatc
    60841 ctgattatgt caacgaatta gacccaaaaa tcgttgatat gctagtagaa tttcacaagt
    60901 cacaaggcac tttggaaact cccgaggcgc aagcagaaat cgcccaaaaa cgtgaagaaa
    60961 tcgagcaaag gagagctgag cttgaggata aaaaacaaga gcttttgaac cgcttgaaca
    61021 aatagagttt cgcaagtatt atgcttacaa attacttgag caattaacta aaatataaac
    61081 cctgcctaga tataaaggca gggtttatat tttagaaatt cacgtaggtt gttacggttt
    61141 ttacataccc agtatagttt gagtttctat agtattcagt gataaacttc cattttcttt
    61201 gagcaacatg gatataagta cttgttatgt agtatggata tgggctttgt gaatccaagt
    61261 aagactgata agcttgtata ccaaaatatg ctccaccaat tattgcaccc catggacccc
    61321 ccaataaagc acctatccta ccaatcatat aactgattcc agcaccagtc atgaagttag
    61381 cgaatgtgtt agcttgttta ttcccatgta ttgtgttgac gtaattccaa acattaggat
    61441 cgtatgatct aaaagatata tttaggtcga tttcattctt ttgataagcc atataaaatg
    61501 ccccattgat atagacgccg tcagcacgtc gttcaatagt gtctacactt ccatctggat
    61561 tgacaacctc aagaacttca tcgcttaaaa tatttacttg cgtatctccg aaccgcactg
    61621 atgagccatt ctcaaactga gcctcaccag atacaacttt agagtttgcc gataagctat
    61681 catcagcaaa aacaacaagc gacggggaaa tgctagacat acagaaaaca gacataacta
    61741 gcaaacacat gcatttaaac atcttagaca taacggaaac tcttttgtat ttttgatttt
    61801 tttcaacttt tattatacaa taaaaccaaa taaaaagaaa gcggtaacaa tatgcttaat
    61861 gcgaaaattt tttatatatt tttatgtttg atcgttatcg aaactacagg cttgttgttg
    61921 ttgaaaagag gtctcgaaat gggttattta gacacagaag ctattatcct cgcagttttt
    61981 tcatttgctt tttacaacct atgttcattc gcttgggtct gctctacaat aaaaaacaat
    62041 aaaaaataaa tagacgtatt ttcaaaaaaa aaaaaaagca tatttatatt agtaaaacga
    62101 cgatttaaat cgtcgttttt tttgtagtac gacgggcatg tcgtatatct gaggtgtaag
    62161 tcctcggtgg gcacctgcta ccggtgaacc caatagcgat tcccaagcct gactatcgtg
    62221 aggtagcggg gagaggaaga gatagcgaaa tcgtggctct acgaacagga acgtgatagc
    62281 aaggcgtata tagcggataa ggaggcttca aactctaaag tccaaaaagg tagtcgtaac
    62341 ctatatgtgt aaatcacgag agtaattgaa ttcggactaa ggtttgtgtg aaaaagataa
    62401 atctttctag agtctaaaga ctctgcgtca gatttcctat ttttactgta accttttaac
    62461 gtcctcatat cttgtataaa cgaggaaaga tgtacgactt atcccgtgag gtttcatgag
    62521 cgctgaaagc gtagtaacaa cgaatcatga gaagtcagcc gagcccatag tagtgaggaa
    62581 acttccgtaa tggaagtgga gcgaaggggt gaacaactaa tcgaagtaat cctacttcac
    62641 ttgtgtctgt aaaacgaacg gtctgataga actggactct gtcacgtatt gactagatga
    62701 aggttcacca atataagatg tccctcaggc accaaaacaa gaaaggaata cgcacatgtc
    62761 aaaattgcta gataagatat tatcacgcga aaatatgctg gaagcctaca atcaagtaaa
    62821 atccaataaa ggctcagctg ggattgatgg aatgactatc gaagagatgg ataattatct
    62881 cagacaaaac tggcgcttga ctaaggaact gataaaacag agaaaatata agcctcaacc
    62941 agttcttaaa gttgagatac ctaaaccaga cggcggcatc cgtcaactag gaattccaac
    63001 agttatggat agaatgattc aacaggccat tgtccaagtc atgagcccca tttgtgaacc
    63061 ccatttctca gatacgagtt atggtttcag accaaatagg tcatgtgaaa aagctatcat
    63121 gaagctctta gaatacttaa atgacggcta tgagtggata gtggatatag acctagagaa
    63181 atttttcgat acagttcctc aagatagatt gatgtcctta gtacataaca ttatcgaaga
    63241 cggagatacg gaatccttga ttcgtaagta tcttcattca ggtgttatca ttaatggtca
    63301 acgttataaa acactagttg gtacaccaca gggaggaaat ttatctcctc tcttatccaa
    63361 tatcatgctt aatgaattgg acaaggaatt agaaaagagg ggacttcgat ttgtgcgcta
    63421 cgcagatgat tgtgtgatta cggtcggaag cgaggcagcc tctaagcgtg tgatgtattc
    63481 agtcagtcgt tttattgaga aacggctagg tttgaaagta aacatgacca agactaagat
    63541 taccagacca agagagttga aatatctagg ttttgggttc tggaaatcat cagatggttg
    63601 gaaaagccgt ccccatcaag atagtgttcg gagatttaag tttaaattga agaaactaac
    63661 acagaggaaa tggagtatag acctaacaag acgtattgag caactgaatt tgtctattcg
    63721 aggatggata aactatttct cattgggaaa tatgaaaagt atagtcgcca gcatagatga
    63781 gcgcttgcct actcgcctac gagtgattat ctggaagcaa tggaagaaga aatcgagacg
    63841 attatgggga ttgcttaagt taggagttcc taaatggata gcagataagg tatctggctg
    63901 gggcgaccat tatcaattag tagctcagaa gtcggtactt aaacgtgcta tatcaaaacc
    63961 agtcctggaa aaacgtggac tggtttcgtg tttggattat taccttgaac gacatgcgtt
    64021 aaaagttagt tgaaccgccg tatgccgaac ggcacgtacg gtggtgtgag aggggctaga
    64081 gattatcctc tactcgatta actcccctga aatttatttt aattatgcaa atttcacgta
    64141 tttttgatgc tgagacgacg atcctgggaa cttttcagat atttttttga ctatctaaat
    64201 ctatcattag aaaagcttag agcgccaaag gatttgagcg tttttctgat ttttaagact
    64261 ttttcccagt ctctttttcg attgaagatg taattattct actaactaac taacttctta
    64321 gtactagcca acaacgataa tcataattcc tcctaaaatt aggaataata aaggcaatag
    64381 tttttgtttt ttcatgtaaa aaacctcact tttgttttct gctattttat gctaaaatat
    64441 taaaaatcaa atttaattcc aaagtttgta actaaagggg gagcgctaca tgtctaattc
    64501 atttgtcaag ttgttagtct ctcaattatt tgcaaattta gcagatattt tctttagagt
    64561 aacaatcatt gctaacatat acattatttc aaaatcagta attgccacat cactagttcc
    64621 tatcttaata ggaatatcct cttttgttgc gagtctttta gttccgttgg ttactaaaag
    64681 gttagcgcta aatagggttt tatctttatc tcaatttgga aagactatat tattggcgat
    64741 actggtagga atgtttaccg taatgcaatc cgtagcgcct ttggtgacct atctatttgt
    64801 tgttgcaatt tccatactag atggttttgc agcacccgtt tcctatgcta ttgtgccacg
    64861 ctatgcgacc gatttgggta aggctaattc agccttatca atgactggtg aagctgctca
    64921 attgataggt tggggattag gtggactctt gtttgcaaca attggtctgt tacctaccac
    64981 gtttatcatt ttagtcttgt atatcatttc tagctttctg atgttatttc ttcctaacgc
    65041 tgaagtggag gtgttagagt cagaaactaa tcttgaaatt ttgctcaaag gttggaagtt
    65101 agttgctaga aatcctagat taagactttt tgtatcagca aatttattgg aaattttttc
    65161 aaatacgatt tgggtttctt ccattatact tgtttttgta acggagttat taaataaaac
    65221 ggaaagttac tggggatatt ctaatacagc atactctatt ggtattataa ttagtggctt
    65281 aattgctttt aggctatctg aaaagttcct tgctgctaaa tgggaaagta ttctttttcc
    65341 tcttgtagct atggcaatag tgacactgac tattctatat tttccaaacg cacagatgtt
    65401 tttattattt tcagctttag ttggtatgtt atcgcaacta aaagaagttc ctgaaagtgt
    65461 atttcttcag gaaacagtag aggaaaatca tttagttaat gtctattccg ttcttgaagt
    65521 gatttctaca ttagcatttt cagtatttgt tttgctaatg agctatatta ctgattttgg
    65581 ctatcagcca tttgtctgat gatagaagct attttaattt atatcagacg agattatttt
    65641 aaatgagaga gtggttaaaa agtctttaaa aatcagaaaa gcgcatagta tcaggtgttg
    65701 aaaaaacttg atattgtgtg ttttattatg ggaagattta cttcattgtc tcctgaaatg
    65761 gagttttgaa gcagaatcac tctatttgaa aatatacata gaaaaaccgc ataatcctta
    65821 aaataagctg aaatctattg gaaacatacg gtaaacaatt gaaaagatac tatataaagt
    65881 ggtacaatgg tagaagaata agctagtaag aatcactctt attttagcga aaaattacag
    65941 aaatgaatgg tttttcttga tgaaacagag aaaagaattg tacctctttc ttggtaggac
    66001 agccttgtat tttcttatct ttctagggct gctttacttc tttagctatc ttggtcaggg
    66061 tcaaggaagc tttatctata atgaatttta acttgaagga gaatccctat tgtgtcaaat
    66121 aaaccaatag cagatatgat tgaaaccatt gagcattttg ctcagacaca gcctagctat
    66181 cctgtctata atgttttggg gcaggaacac acttatggcg atttaaaggc tgattcggat
    66241 agtttggctg cagtcattga ccaactaggc ttgcctgaga agtctcctgt ggttgttttt
    66301 ggtggccaag aatatgaaat gttggcaacc tttgtagcgc tgactaagtc aggtcatgcc
    66361 tacattccaa ttgatagcca ttcggccttg gagcgagttt cagctatttt agaagtagca
    66421 gagccaagct tgattattgc catttcagcc tttcccttgg agcaggtttc tacaccaatg
    66481 ataaatctag ctcaggttca agaagccttt gcccaaggga acaactatga aatcacgcat
    66541 ccagtcaagg gagatgataa ttactacatt atctttactt ctggtacgac tggtaagcct
    66601 aagggagtgc agatttcaca tgataatctc ctcagcttta caaactggat gattacggat
    66661 aaggaatttg cgacaccgag tcgtccgcaa atgctggcac aaccacctta ttcttttgac
    66721 ttgtctgtca tgtattgggc accgaccttg gcacttggtg gtacgctttt cactcttcct
    66781 tcagtcatca ctcaggactt taagcaactc tttgcggcta tcttttcatt gccaatcgct
    66841 atctggacat caacaccatc ctttgcagat atggccatgt tgtctgaata cttcaacagt
    66901 gagaaaatgc ctggaatcac gcatttctac tttgatggtg aagaattgac ggtcaaaaca
    66961 gctcaaaaac tgcgcgagcg tttcccaaat gcccgtatca tcaatgctta cggcccaaca
    67021 gaagcgacag tagctctgtc agcagttgcc gtgacagacg agatgttagc gactctcaaa
    67081 cgcctaccaa tcggctatac caaggctgat tctccaacct ttatcattga cgaggaagga
    67141 aataaactgc caaatggcga acagggagaa atcattgttt ctgggccagc tgtttcaaaa
    67201 ggttatatga acaatcctga aaaaacagca gaagccttct ttgagtttga aggtctgcca
    67261 gcctatcaca caggcgatgt gggaaccatg acagatgagg gcttgcttct ctacggcgga
    67321 cgcatggact tccagattaa gtttaacggt taccgcattg agttagaaga tgtctctcaa
    67381 aacctcaaca agtctcgctt tatcgaatct gctgtcgcag taccgcgcta taacaaggac
    67441 cacaaggtac aaaatctatt ggcttatgtc atcttaaaag acggtgttcg tgagcagttt
    67501 gagcgagata tcgatattac caaggccatc aaggaagacc tgacagacat catgatgtcc
    67561 tatatgatgc catctaaatt cctttaccga gacagtttgc cactaactcc aaatggaaag
    67621 attgacatca aaggattgat taacgaggtg aataagagat gatggagttt tttcaacagc
    67681 ttcctcattt agagccatat ggcaatcctc agtattttgt ttatgtgatt gctgcaacct
    67741 tgcccatctt tataggtctc tttttcaaga aacgctttgc ctggtatgaa gtgttggtaa
    67801 gtctcttctt tattgtcacc atgttggtgg gtggaaagac caatcaacta gctgccttgg
    67861 gtatttacct ttgctgggaa atattgctcc tgcttttcta caagcattat cgaaaaagca
    67921 aggatggcaa gtgggtcttc tacttagtta gttttctgtc cctacttccg attatctttg
    67981 tcaaggtgca accagctatc aatggaacgc agtctttgct tgggttcttg ggaatttctt
    68041 acctgacctt tcgttcggtt gggattatca tcgagctgag agatggagtg attaaggatt
    68101 ttaccctctg ggaattcctc cgtttccttc tcttcatgcc aactttctcg agtggtccaa
    68161 tcgatcgttt taagcgattt aatgaaaatt atcaggccat tcctgagcga gatgagttga
    68221 tggatatgct ggatgaatct gtccgctata tcatgcgggg ctttttgtat aagtttatcc
    68281 tagctcatgt tttaggagag accttactac ctcctctgaa gaatttagcc ttgcagtcag
    68341 gtggcttctt taatctctat gccttggcag ttatgtatac ttttggtctg gagctcttct
    68401 ttgactttgc aggttattct atgtttgctt tggccatctc aaacttgatg ggaatccgta
    68461 gccctatcaa ctttaacaag ccctttttat caagggattt aaaggagttt tggaatcgct
    68521 ggcatatgag tctgtccttc tggttccgtg actttgtctt tatgcgaatg gtgatggtgt
    68581 taaccagaaa gaaagtcttt aaaaatcgta atgtaacctc aagcatggcc tacattgtaa
    68641 atatgctgat tatgggattt tggcatggtg tgacctggta ctatatcgcc tatggactct
    68701 ttcatggact aggcttggtc atcaatgatg cctgggttcg caagaaaaaa acgctcaata
    68761 aggaacggaa aaaagcaggg aaggctgccc tacctgagaa tcgctggatt cagttgcttg
    68821 gcatggttgt cactttccat gttgtcatgt tgtcattctt aatcttttct ggattcttga
    68881 ataatctatg gtttaaaaaa taaaaggaaa taaaatatgg atatcaaatc agaagttatc
    68941 gaaattattg atgagttgtt tatggaagat gtttctgaca tgatggatga agatcttttt
    69001 gatgcaggtg tcttggatag tatgggaacg gttgagttga ttgtggagat tgagaaccgt
    69061 tttgacattc gtgtccctgt aacagagttt ggtcgtgacg actggaatac agctaataaa
    69121 attatagctg gtattgtgga gctacaaaat gcttaaacgc ttatggatga tcttcggacc
    69181 ggtcttgata gctggtttgt tggtttttct gctcattttc ttttatccta ctgagatgcg
    69241 tcataatcta ggagctgaaa agcgttcagc ggtggctact actatcgata gttttaagga
    69301 gcgaagtcaa aaagtcagag cactatctga tccaaatgtg cgttttgttc ccttctttgg
    69361 ctctagtgaa tggcttcgtt ttgacggtgc tcatcctgcg gtattagctg agaaatacaa
    69421 tcgttcctac cgtccttatc ttttaggaca ggggggagct gcatcgctta accaatattt
    69481 tggaatgcaa cagatgttac cacagctgga gaataaacaa gttgtgtatg ttatctcacc
    69541 tcagtggttc agtaaaaatg gctatgatcc agcagccttc cagcagtatt ttaatggaga
    69601 ccagttgact agttttctga aacatcaatc tggggatcag gctagtcaat atgcagcgac
    69661 tcgcttactg caacagttcc caaacgtagc tatgaaggac ctggttcaga agttggcaag
    69721 taaagaagaa ttgtcgacag cagacaatga aatgattgaa ttattggctc gttttaatga
    69781 acgccaagcc tccttttttg gtcagttttc ggttagaggc tatgttaact acgataagca
    69841 tgtagctaag tatttaaaaa tcttgccaga ccagttttct tatcaagcaa tagaagatgt
    69901 tgtcaaagca gatgctgaaa aaaatacttc caataatgag atgggaatgg aaaattattt
    69961 ctataatgag cagatcaaga aggatttgaa gaaattaaag gattctcaga aaagctttac
    70021 ctatctcaag tcgccagagt ataatgactt gcagttggtt ttaacacagt tttctaaatc
    70081 taaggtaaac ccgattttta tcattccacc tgttaataaa aaatggatgg actatgctgg
    70141 tctacgagag gatatgtacc aacaaacggt gcagaagatt cgctaccagt tagaaagtca
    70201 aggttttacc aatatagcag atttttctaa ggacggtggg gagcctttct ttatgaagga
    70261 caccattcac cttggttggt tgggttggtt ggcttttgac aaggcagttg atcctttcct
    70321 atccaatccc acaccagctc cgacttacca tctgaatgag cgctttttca gcaaagattg
    70381 ggcgacttat gatggagatg tcaaagaatt tcaatagata atataatata gaagagttca
    70441 agaatgaaac tagttttcac gttttttctt gactcttttt ttgcttgtga tataattaac
    70501 tggtaaacaa aatgtcaaag aatagtattt ttctcttaaa aaagagaagt ctaaaaggaa
    70561 aggagtcaga tatgagacag ctagcaaagg atatcgatgc ttttttgaat gaggtgattt
    70621 tgcaggcgga aaatcagcat gaaatcctaa taggtcattg cactagcgag gtggccctga
    70681 ccaatactca ggagcatatc cttatgctct tgtcagagga atctttaaca aattcagaat
    70741 tggcccgtcg tctcaatgtc agtcaggcgg cagttaccaa ggccattaag tctttggtca
    70801 aggaagggat gttggaaaca tctaaagatt ctaaagatgc gcgtgtgatt ttttatcagt
    70861 tgactgactt ggctcgtcca atcgctgagg agcaccacca tcaccatgag catacacttt
    70921 taacctatga acaagtggcg actcagttta ctccaaatga acaaaaagtg attcagcggt
    70981 ttttgactgc tttagtagga gaaatcaaat aatgagatat attacggtag aggatttgtc
    71041 cttctattat gataaggagc ctgttcttga acatatcaat tatagtgttg atagtgggga
    71101 atttgttacc ttgactgggg aaaatggagc ggctaagacg acgctcatca aggctagtct
    71161 tggaattctg caaccacgca ttggaaaggt ggctatttca aagacaaata cgcaaggtaa
    71221 gaaattgaga atagcctatc ttcctcaaca aattgccagt tttaatgctg gttttccaag
    71281 tacggtctat gaatttgtca agtcgggtcg ctatccgaga aaaggctggt tccgtcgttt
    71341 gaatgctcat gatgaggagc atatcaaggc cagtctggac tcagttggca tgtgggaaca
    71401 tcgagacaaa cgcttggggt ctctatctgg gggacaaaag cagcgagcgg tgattgcgcg
    71461 tatgtttgct tctgaccctg atgtgtttat cctagacgag ccaacaacgg ggatggatgc
    71521 aggaagtaaa aatgaatttt acgaactcat gcaccacagc gcccatcatc atggcaaggc
    71581 tgttttgatg attacccatg accctgaaga agttaaggat tatgcggatc gcaatattca
    71641 tctagtccgt aaccaagact cgccatggcg ttgtttcaat gttcatgaga atggccagga
    71701 ggtgggccat gcttagttta ttatcttacg actttataca acgcgccttt ttggcggtta
    71761 ttgctatgag tcttttctca ccggtattgg gaaccttcct catcttgcgt cgtcagagtt
    71821 tgatgagtga tacccttagc cacgtctcac tttcaggtgt agcctttggt ctggttttgg
    71881 ggatttctcc aactatttct actattgcca ttgtcttgat tgcggcggtc tttctggagt
    71941 atctccgtac ggtttacaag agctttatgg aaatcgggac agctatcctc atgtcaacag
    72001 gtctggctgt ttctctgatt gtcatgagca agggtaaaag ctcgagttca atgagtttgg
    72061 accaatatct ctttggttcg atcgtgacta tcagtgaaga acaggtcatt tccctctttg
    72121 tcattgcggc ggttgttttg attttgacct ttctctttct tcgtcctatg tatatcttaa
    72181 cttttgacga agatacggcc tttgtggatg gcttgccagt tcgtaccatg tccattcttt
    72241 ttaacatggt gacaggggtg gctattgccc ttatgattcc tgcagcagga gctcttctgg
    72301 tatcgaccat tatggtcttg ccagctagta ttgccctgcg tctggggaaa aactttaaat
    72361 cggttatgct gcttgccagt gcgattggct ttttgggaat ggtagcagga ctttacattt
    72421 cctactatgc agaaacacct gcaagtgcaa gtattaccat tatttttgta actgtcttta
    72481 tactaatcag tttagtaaga cgttttatca aataggagac gaacgtgaaa aaaattagct
    72541 tattactagc cagtctatgt gccttgtttt tagtggcttg ttccaatcaa aaacaggcag
    72601 atggtaaact caatatcgtg acaacctttt accctgtcta tgaatttacc aagcaagtcg
    72661 caggagatac ggctaatgta gaactcctaa tcggtgctgg gacagaacct catgaatacg
    72721 aaccatctgc caaggcagtt gccaaaatcc aagatgcaga tacctttgtt tatgaaaatg
    72781 aaaacatgga aacatgggta cctaaattgc tagatacctt ggataagaaa aaagtgaaaa
    72841 ccataaaggc gacaggcgat atgttgctct tgccaggtgg cgaggaagaa gagggagacc
    72901 atgaccatgg agaagaaggt catcaccatg agtttgaccc ccatgtttgg ttatcaccag
    72961 ttcgtgccat taaactagta gagcacattc gtgacagctt gtcagcagat tatcctgata
    73021 aaaaagagac ctttgagaag aatgcagctg cctatatcga aaaattgcaa gccttggata
    73081 aggcttacgc agaaggcttg tctcaagcaa aacaaaagag ctttgtgact caacacgcag
    73141 cctttaacta tcttgccttg gactatggac tcaaacaagt cgcaatctca ggactttctc
    73201 cagatgcaga gccatcagct gctcgcttgg cagaattgac agagtatgtc aagaaaaata
    73261 aaatcgccta tatctatttt gaagaaaatg cctcacaagc ccttgctaac acactttcaa
    73321 aagaagcagg tgtcaaaact gatgtcctca atcctttaga aagtctgaca gaagaggacg
    73381 ccaaggctgg agaaaactac atttccgtga tggagaaaaa cctcaaggct ttgaaacaaa
    73441 caacagacca agaaggccca gcaatcgaac ctgaaaaggc agaggatacc aagacagtcc
    73501 aaaacggtta tttcgaggat gcagctgtca aggaccgcac cttgagtgac tatgcaggta
    73561 actggcaatc agtttatcct ttccttgaag acggcacgtt tgaccaagtc tttgactaca
    73621 aggctaagtt gactggtaag atgacccagg ctgagtacaa ggcttactat acaaaaggct
    73681 atcagacaga tgtgactaag attaacatta ctgataatac tatggaattt gttcaaggtg
    73741 gacaaagcaa gaaatacact tacaagtatg tcggtaagaa aattttgact tacaagaaag
    73801 gcaatcgtgg cgtgcgtttc ctctttgaag ccacagatgc tgacgctgga cagttcaagt
    73861 atgttcagtt tagtgaccac aatattgccc cagttaaggc agaacatttc catatcttct
    73921 ttggaggcac aagccaagaa gctctatttg aagaaatgga taattggcca acctactatc
    73981 cagataacct atctggccaa gaaatcgctc aagaaatgtt ggcgcattga tgagaaatcg
    74041 actagttcat aagagctagt cggttttttg atactagatg gctaacttca ttatagacct
    74101 ttcagaactt taaacaataa ataaaactct tgaaatatct gggcttatat gctagaatgt
    74161 agttagtgta taaggttcat tagaacacca aagcccctaa ctagtgccat agttaagggc
    74221 ttttttgacg tatcttagcg atttaacggg tgtttatagg ctagtcagtc ggtctacttc
    74281 ttaccatcta gccatttgca gacgaaatac aagataattc cagctataac atctgctata
    74341 atagtaagag caagctctgg tataaggctc attagtttca cctcctctca cgaacccata
    74401 ggaacgtaat cggtaaccga tgacaaaagt attatatcac actaaattta gatcatcaac
    74461 ctcacttaat gcttgaacta ttgtagatta tatgctaaaa tgtagttaat tgataaggtt
    74521 cattagaaca ccaaagcccc taactatggc cgtagttaag ggcttttttg acgtatctta
    74581 gcgatttaac gggtgtttat aggctagtca ctcggtctac ttcttactat ctagccatct
    74641 gcagacgaaa tacaagataa ttccagctat aacatccgct ataatagtaa gagcgagctc
    74701 tatgataagg ctcattagtt tcacctcctc tcacgaaccc ataggaacgt aatcggtaac
    74761 cgatgacaaa aatagtatac cacaatacat ttagatcatc aaggtcactt aattcttgaa
    74821 atatagggtc taggcgacaa agtctttaaa atcagaaaaa cgcataatat caggtgtgca
    74881 aaaacttgat actatgcgtt ttattgtggg aaggtttact ccattttctc ctgaaattga
    74941 gtttttgtcc agcctctgtt tttagggttg ctgagaaaat aatgtcatgt ggtgaatatt
    75001 tgtaaatcag tcagcagaca gaacgaatac tcttcgaaaa tctcttcaca tcatgtcagc
    75061 ttcgtctttc cgtatatatg tgactgactt catcagttct atctacaacc tcaaaacagt
    75121 gtttcgagct gacttcatca gttttcaaat ctgtactttg agcaagctga gactagcttc
    75181 ctatttgatt ttcattgaat atcagaaacc cattctccat caaataattc gactgcgtct
    75241 aataattttt ggtctggcaa ggtgtcagaa ataaaggttg tgtatttgga gaggggatta
    75301 attttaaaaa atccagtctt gtaaaattta gaactatcaa tcagtaagat ggtttcatgg
    75361 gctttgtcaa taatattctt ttttgaaata gcttggctga gagaagcttc ataaacatat
    75421 tggtcatcaa tacctcttgc tgaacaaaat gctaaatcga tattaaaatg atctaataaa
    75481 gaattttcct tatcatagtt gaccacggaa caggattgat gtttgacctc gccagatgtg
    75541 ataaagattt tggagctatc tttaacagtt tcagataggg tttgtgcagt atgtaaacca
    75601 tttgtaaaaa taatcaaatt atcaagttca gaaagatagg gacagagttc gtagacagta
    75661 gtactggaat ccagatagat acacatacca gaccgaataa agtctttagc gagactagcg
    75721 attagtcttt tttgcctagt actttctcct tcccgtattt gatgagaaag ttcaattgtg
    75781 ttcatagagg acagggtcac gtatccgtgc tttcttttga taagaccttg attttctaag
    75841 aaaattaaat cacgacgtaa ggtacttgtg ctggagaaag tgatttctgc cagctctttt
    75901 acggcaattc tttttttctt tttaataatt tcaatcaatt caagtacacg ttcatctttt
    75961 atcataagct cctcctaatt tatcatttca actatattat agcacaaatt ggaggaattt
    76021 gaattatttt tatgaatatt gggttaacat ttgaacatta ttcaagtaag cgttcacata
    76081 ttgaaaaaat aaaacgtggg gattataata aagttaatca aggacgaaga gagaagaaaa
    76141 atggaagcgg ttttagcaat agatttaggt gcgacttctg gaagagcaat cgttggttac
    76201 ctttctgaaa ataaactagt aatggaagaa ataaatcgct tttctaatct acctattaga
    76261 gtaaaagggc atttatcttg ggatattgac tttctactag ctaaaattct tgaaagtatc
    76321 cgcttggcta atactagtta caagatttta tctatcggta ttgacacatg gggagttgat
    76381 tttggactga ttgataatga aggtaagctg ttatcacaac ctgttcatta tcgtgatgaa
    76441 agaacaaagg gagtgttaaa ggaaatatct gaaatgactg aattagaaaa actgtattca
    76501 gagacaggaa atcagattat ggagataaat accttgtttc aactctttaa ggcacgtcaa
    76561 gaatctcctg actctttcta taagaccaat aagattcttt taatgccaga tttgtttaat
    76621 tatctcttga caggtaagtt tgctacagaa aaaagcattg cttcaacaac tcaattattt
    76681 gatcctagga gtcaaaattg gaatcagaat atcttaaaac tatttgaatt ggattcatct
    76741 ttacttcctg aaattgtttc agagggaaat gttcttggaa ggataaaaga ggagtatggt
    76801 ttatgcgata ttcctgttgt gaatgtttgt agtcatgata cagcaagcgc gattgtctca
    76861 gtacctaaga cagaaggtag tttatttatt tcatcaggta cttggtcttt ggttggagtg
    76921 gaacttactt caccgattct tactaccgaa tccttcagtt atggatttac aaatgaagtc
    76981 ggtaaagatg gagtgattac atttctgaag aattgtacag ggttgtggat catagaggaa
    77041 ctaagacgtt catttgaacg aagagggaaa gcctattctt ttgatgatat taggacaatg
    77101 gtggagaaag aaaaagaaaa tcttcctctg attgatactg aatcaactga atttgcaaca
    77161 gaatctgata tgcacaagac tttgacagaa tatctagctt atcatcatga aactagagag
    77221 tggacagatg gacaactatt taagattgtt tatgaaagcc tagctgaaac gtataggaaa
    77281 gcgatagagt tactagaaga actaactcat aaggtttata agaggatata tgtgattgga
    77341 ggaggtgcta gagccagtta ctttaaccaa atgattgctg atagaactgg taaagaggtt
    77401 cttacaggtt cgactgaggg tacagctgtg gggaatattg ttgtgcagct catagctatg
    77461 ggacaattaa aagggatgga agaggctcac catgttattg aggagtttct acaattagag
    77521 agttattact tccaaaagaa ttaaaaagat tgagagtttg taaatttgcc tccctccccc
    77581 ttcttagctt ttgtgcagga aggggggata attggtgaat tgaaaaatat ttagtgtttt
    77641 gatatgagga ggacaaggat gtcagatgta aaacaagaat taattaaata tggtaagaag
    77701 ctagtagaaa cagatttgac gaaaggaaca ggtgggaatc tcagcgtttt cgatcgtgaa
    77761 aaacaattga tggcaattac cccgtcgggt attgatttct ttgaaatcaa agaatccgat
    77821 attgtagtga tggatattaa tggaaatgtt gtagagggag aacgcttgcc atctagcgaa
    77881 tggtatatgc atttgattca atatcaaact cgtgatgata tcgatgcaat tatccatgct
    77941 catacaactt atgcaacagt attagcttgt ctcagagaac cacttccagc gagtcattat
    78001 atgattgcag tggcagggaa agatgttcgg gtagctgagt atgcaacata tggcacgaaa
    78061 gaattggctg tgaatgcagc taaagcaatg gaaggtcgta gagcagtttt actagcgaat
    78121 catggaattt tagcaggtgc acaaaattta ttgaatgcat ttaatattgt tgaagaagtt
    78181 gaatattgtg caaaaattta ttgtttagct aagaattttg gagagccagt agttcttcct
    78241 gatgaggaga tggaattgat ggcagaaaaa tttaaaacat acggtcagag aaaataggga
    78301 ggatattaat gttaaaacat ataccgaaaa atatttctcc agatttattg aagactttaa
    78361 tggaaatggg acatggagat gaaatagtat tagctgacgc gaattaccct tccgtctcat
    78421 gtgcgaataa attaattcgt tgtgatggtg taaatattcc agaattatta gattccattc
    78481 tgtatttaat gccattagat agttacgtcg atagttcaat tcagtttatg aacgttgttt
    78541 cgggtgatga tattcctaag atatggggta cctatagaca gatgattgaa ggtcatggta
    78601 cagatcttaa aacgattact tatcttagaa gagaagactt ttatgaacgt agtaagaaag
    78661 cttatgctat tgttgctaca ggagaaactt cactttatgc taatattatc cttaagaaag
    78721 gagtagttgt tgaaagagaa aatgtttaat agaggaattt tagttgccag tcatggtaat
    78781 tttgctagcg gagctctcat gaccgcagaa atgtttgttg gtgagacaac aaatgataga
    78841 gttaggacat taggtttgat gcctggagag aatattgtag agtttgagca ttattttaaa
    78901 aatcaagtgg atgaactgtt agactcaaat caagaggtta tcgttttgac tgacttgatt
    78961 ggaggaagtc ctaataatgt tgctttgtca cggtttttaa atttggattc agttgatatt
    79021 gtaacagggt ttaatatccc tctcctagtg gaattaatat caaattatga ttcaaaaatc
    79081 aatttagaag aaattgttca caatgctcaa aatagtttgt ttaatgttaa acaacaactt
    79141 aacgtagagg aggaagaaga tttatgtcta tagagtttgt tcgtattgat gaccgtctgg
    79201 tacatggtca agttgtcact acgtggctaa aaaagtatga tattgagcaa gttatcattg
    79261 ttaatgatcg catctcagaa gataaaacac gacaatctat tttaaagatt tctgcaccag
    79321 taggtttaaa aattgttttc tttagtgtaa aacggtttgt ggaagtttta aactctgtgc
    79381 caataaaaaa gagaacaatg ctgatatata caaatccaaa agatgtgtat gattctattg
    79441 aaggaaattt aaaattggag tacctcaatg taggacagat gagtaaaacg gaggaaaatg
    79501 aaaaggtaac gggaggtgta gctctaggtg aagaagacaa atattatttt aagaaaatag
    79561 ttgataaggg aacgagagtt gaaattcaaa tggttcctaa tgataaagtt acaatgttgg
    79621 aaaaattttt ataaaaataa tttaaggagg tacagtatat gctattcaca caagcattac
    79681 tggtaacatt agttgggatt attgccacta ttgactataa tggaccgtta tttatgattc
    79741 accgtccgtt agttacaagt gcaatggttg gcttagtctt aggagatttc acccaaggtg
    79801 ttcttattgg ttcagctctt gaattaactt ggctcggtgt aacaggtatt ggaggttaca
    79861 ctccaccaga tactatttca ggtgcgatta ttggtactgc atttggtatt ttatctggtc
    79921 aaggagaaac tgctggtatc gctatagcag ttccaattgc agttgctacc caacagttgg
    79981 atgttcttgc aaaaacttta gatgtttatt ttgtgaaaaa agctgataat gatgctaaaa
    80041 acggagatta ttcaaagatc ggtttttatc attattcaag tttagtttta atcacgttat
    80101 ttaaaattgt accaattttc ctagctatta tgcttggagg ggaatatgtg gcagacttgt
    80161 ttgctaaggt tccaccaatc gttatgcagg gacttaactc tgcaggtgct ttactacctt
    80221 caattggttt tggtatgctt ttaaatatga tgctcaagaa aaatatgtgg gtattcttgt
    80281 tgattggatt catttgttct gtgtatggag gaatgtcaac cattgggatc tcactagttg
    80341 gtattgcggt agcatacttc tacgatatga ttggaagtaa accacaagaa acaacttcaa
    80401 gtagtgatgt tgaggaggat cttgatctat gatgaataat aaagtaacta aagttgaact
    80461 taaaaaagtt ttcaaacgaa gttttatgta tggttcttca tggaactatg agagaatgca
    80521 gaacctaggt tttctatata caattcttcc agtattgaaa aaactatacc cagacaaaga
    80581 ttcagcttct cctgcaatga aacgtcacct tgagtttttc aatactcatc aaacagcggc
    80641 accatttatt cttggagtta cttccgctat ggaagaacaa gaaggaaatg aaggtgcagc
    80701 ttcaattact ggtattaaag ttggcttgat ggggccactg gctggtctag gagatagttt
    80761 gttctggctg acactagttc ctatctgttt tagtattggt gcgtcttatt ctaaagacgg
    80821 cggtgcttta ggtatcttta tcgccttaat attgtttaat attattaata ttcctgttaa
    80881 atatttcggt ttgaaatatg ggtatactaa gggttctagt cttatccaag aaaataatac
    80941 aaaaggaaca ttgaatcgcg ttacgagtat ggcgacagca ttagggctag tactagtggg
    81001 tggtttgatt ccatcaatgg ttggtattaa ttttggatta gaatttaagc agggggaact
    81061 tgttatttct gttcaagaaa tgattacaaa attaattcca ggatttatcc ctatggcttt
    81121 gactttatta atgtgtaaat taattagaaa aggaaagaat ccggttgtac taatctttag
    81181 tgttatggct attggagtta tcctagttgt tttaggaatt ttgaagtagt agaaagtgtg
    81241 gaggtggtat ttgggatatc acctccattt tggaagagag gtaaagagtg aaattatggt
    81301 ataagaaagc tgcctcaaat tggaatgaag ccttgccgat tgggaacggt catttaggtg
    81361 gtatgattta tggttcagct acaaaagaat gtattcaact aaacgatgag actatttggt
    81421 atagaggaaa gtcagataga aataatccag actcactatt gcatcttaaa aaaattcggg
    81481 aatatctttt agatggagaa attcagaaag ccgaagaatt gataaagtta acaatgtttg
    81541 ctaccccaag agatcaaagc cactatgaat tacttgggga actttacatt gagcatatag
    81601 atattcagtc ttgtgctctt tcattgtatg aaagagagct agatttagat acagctattt
    81661 ctaatgttgt gtttgagcct aatagttgta atttacaaat aaaaagagaa tattttacga
    81721 gttttaataa gaatatttta tgttgccgta tagtgtcatc agttcaaaac acattaaatt
    81781 taaacattaa tttgggtaga aataaacggt ttaatgacga agtatctaaa ctggattcaa
    81841 gtacaatttt aatgtcggcc tctgctggag gtagaaaagg tgttcagttt aaagtagtat
    81901 gtcattctaa ggttacggat ggtgaagtaa gtgtattggg agagacaata gttattcgga
    81961 atgctacaga ggtatttctt tatctcaaat caatgacgga ttattgggga aatatagata
    82021 tttcttctct tcagggagaa tttagtagta ttgattactt tacagaaaaa gatgaacatg
    82081 taaaaaaata tcaggagcaa tttaatagag ttgattttaa actagactat agtaaagatt
    82141 gtcttagcat tccaacgaat ctacttcttg aaaacactaa aaagtatagt aactacttga
    82201 ctaacttgtt atttcattat ggaagatatc tgttaatatc gtctagtcaa ccgaatggtt
    82261 tacctgccaa tcttcaagga atatggtgtg atgaattaaa tccaatttgg ggttctaaat
    82321 atacgattaa tattaatact caaatgaatt attggatggt aggtccatgt gatttaccag
    82381 aagtagaata tccattattt gatatgctcg aaagaatgag agaaccggga agactaaccg
    82441 ctaagaaaat gtatggagct agaggtttta cagcacatca taatacggat ggttttggcg
    82501 atacggctcc ccaatctcat gccatggggg ctgcaatttg ggtattaact attccatggt
    82561 tatgtactca tatttgggag cactatttat atttccaaga tgagcgtatt cttacggaac
    82621 attttgaaat gataaaagaa gcatttcttt tctttgaaga ttatttattt gaggtggatg
    82681 gctacttgat gacaggtcca agtgtctcac cggaaaataa atatcgctta aaaaatggta
    82741 ttgaaggaaa tgcttgtcta tcatctacaa ttgataatca aattctaaga tatttttgtg
    82801 attcatgcat tggcattgca aaacaattag gagacaattc ggattttatt agtcgtgtga
    82861 aggagttaaa aaagaaacta cctaaaacaa aaataggtag taatgggcaa atccaagaat
    82921 ggttagaaga ttatgaagaa gtagagcctg ggcatagaca catttcacct ctatttgggc
    82981 tttatcctta taatgagatt gatattcata aaactccgga attagcagaa gcagctaaaa
    83041 tcactatcaa taggagatta tcaaacgcta actttttatc ttcacaggag agggagcaag
    83101 cgattaataa ttggttagta agtggtttgc atgctagtac acaaacaggt tggagtgctg
    83161 catggctgat tcattttttt gcgagactat atcaaggtga acctgcttat aaccagatta
    83221 atggtttgtt aaataatgcg actcttggca atttatttct tgaccatcca ccatttcaaa
    83281 ttgatggtaa tttaggtttg gtgagtggaa tttgtgaatt attagtacag agccatcata
    83341 attggttatc actaattcca gctttacctt ctgcttggtc agaaggagaa gtgaaaggtt
    83401 tcagagtaag aggaggatat aaggtatcgt ttgcttggaa aaatggggat ataacattcc
    83461 taaaattgga aggaggaaac aaagatcaaa aagtaagagt aagaatatat ggcaaaaata
    83521 ctgatgtaca aaatattgaa ttggtattta attcagaaaa aattattgag ttaaattttt
    83581 aggtataagt catgaataaa gaaaaaataa aaagaaaatt aatcacaata ctgtttgtat
    83641 gtattgggat gttatgtttt ggattgttag caggagttaa ggctgataat cgtgttcaaa
    83701 tgagaacgac gattaataat gaatcgccat tgttgctttc tccgttgtat ggcaatgata
    83761 atggtaacgg attatggtgg gggaacacat tgaagggagc atgggaagct attcctgaag
    83821 atgtaaaacc atatgcagcg attgaacttc atcctgcaaa agtttgtaaa ccaacaagtt
    83881 gtattccacg agatacgaaa gaattgagag aatggtatgt caagatgttg gaggaagctc
    83941 aaagtctaaa cattccagtt ttcttggtta ttatgtcggc tggggagcgt aatacagttc
    84001 ctccagagtg gttagatgaa caattccaaa agtatagtgt gttaaaaggt gttttaaata
    84061 ttgagaatta ttggatttac aataaccagt tagctccgca tagtgctaaa tatttggaag
    84121 tttgtgccaa atatggagcg cattttatct ggcatgatca tgaaaaatgg ttctgggaaa
    84181 ctattatgaa tgatccgaca ttctttgaag cgagtcaaaa atatcataaa aatttggtgt
    84241 tggcaactaa aaatacgcca ataagagatg atgcgggtac agattctatc gttagtggat
    84301 tttggttgag tggcttatgt gataactggg gctcatcaac agatacatgg aaatggtggg
    84361 aaaaacatta tacaaacaca tttgaaactg gaagagctag ggatatgaga tcctatgcat
    84421 cggaaccaga atcaatgatt gctatggaaa tgatgaatgt atatactggg ggaggcacag
    84481 tttataattt cgaatgtgcc gcgtatacat ttatgacaaa tgatgtacca actccagcat
    84541 ttactaaagg tattattcct ttctttagac atgctataca aaatccagct ccaagtaagg
    84601 aagaagttgt aaatagaaca aaagctgtat tttggaatgg agaaggtagg attagttcat
    84661 taaacggatt ttatcaagga ctttattcga atgatgaaac aatgccttta tataataatg
    84721 ggagatatca tattcttcct gtaatacatg agaaaattga taaggaaaag atttcatcta
    84781 tattccctaa tgcaaaaatt ttgactaaaa atagtgagga attgtctagt aaagtcaact
    84841 atttaaactc gctttatcca aaactttatg aaggagatgg gtatgctcag cgtgtaggta
    84901 attcctggta tatttataat agtaatgcta atatcaataa aaatcagcaa gtaatgttgc
    84961 ctatgtatac taataataca aagtcgttat cgttagattt gacgccacat acttacgctg
    85021 ttgttaaaga aaatccaaat aatttacata ttttattgaa taattacaga acagataaga
    85081 cagctatgtg ggcattatca ggaaattttg atgcatcaaa aagttggaag aaagaagaat
    85141 tagagttagc gaactggata agcaaaaatt attccatcaa tcctgtagat aatgacttta
    85201 ggacaacaac acttacatta aaagggcata ctggtcataa acctcagata aatataagtg
    85261 gcgataaaaa tcattatact tatacagaaa attgggatga gaatacccat gtttatacca
    85321 ttacggttaa tcataatgga atggtagaga tgtctataaa tactgaaggg acaggcccag
    85381 tccctttccc aacaccagat aaatttaatg atggtaattt gaatatagca tatgcaaaac
    85441 caacaacaca aagttctgta gattacaatg gagactctaa tagagctgtg gatggtaaca
    85501 gaaatggtaa ttttaactct ggttcggtaa cacacactag ggcagataat ccctcttggt
    85561 gggaagtcga tttgaaaaaa atggataaag ttgggcttgt taaaatttat aatcgcacag
    85621 atgctgagac tcaacgtcta tctaattttg atgtgattct atatgacaat aatagaaacg
    85681 aagttgctaa gaaacatgtt aataatttgt cgggtgaatc tgttagtcta gatttcaaag
    85741 aaaaaggagt aaggtatatt aaagttaaat tactaacgag tggtgtacct ttgagtttag
    85801 cagaagtaga ggtttttaga gaatcagatg gtaagcaatc tgaagaagat atagataaaa
    85861 taacagaaga taaagtagtt tctacaaata aggtagctac tcaaagttca actaattatg
    85921 aaggtgtggc tgccttagca gttgatggta ataaagacgg agattatgga catcattcgg
    85981 tgactcatac taaggcagat tctaatgctt ggtggcaggt cgatctggga gaagagttta
    86041 cagtttctaa agttgatatt tataatagaa cagacgccga acctcagcgt ttatctaatt
    86101 ttgatgttat ttttctatct tcatcaggag aagaagtttt tagaagacat tttgataaag
    86161 tagttgatgg tctgttatct ttaaaagtac cttctgtagg ggctaagcta gtcaaaatag
    86221 aattaaaatc atcagctatt ccgttaagtt tagcggaagt tgaagtctat ggttcaaaga
    86281 gaactccgaa gaaactttcc aatattgcgt tagcaaaaga aactagacag agttcaacgg
    86341 attacaatgg tttttctcgt ctagcagttg atggaaataa aaacggagat tatggtcatc
    86401 attcagtgac tcataccaaa gaagattctc cttcatggtg ggagatagat ttagcacaaa
    86461 ccgaagaatt agaaaagtta attatttata atagaacaga tgctgaaatt cagagattat
    86521 caaattttga tattattata tatgattcaa atgattatga agtttttaca caacatattg
    86581 acagtttaga aagcaataat ctatccatag acttaaaagg actgaaggga aaaaaggtta
    86641 gaatttcttt gagaaacgca ggaattcctt taagtttagc agaggtagag gtttatactt
    86701 ataagtaatt ttaaaaatta tcacccaggc taccgtaaat ataatggaga tggtagtatg
    86761 aaagaaacag aaaaataaga ggaaaatatt atgattcaac atccacgtat tggtattcgt
    86821 ccgactattg atggtcgtcg tcaaggtgta cgcgaatcac ttgaagtaca gacaatgaac
    86881 atggctaaaa gtgtggcaga tttgatttct agtacattga aatatccaga tggggaacct
    86941 gtggaatgcg tgatttctcc atctactatt ggccgtgtac cagaggctgc agcttcccat
    87001 gagttgttta aaaaatcaaa tgtttgcgca acaattacag ttacaccatg ctggtgttat
    87061 ggtagtgaaa ctatggatat gtctccagat attcctcatg ctatttgggg atttaatggg
    87121 acagaacgcc caggagctgt ctatcttgca gctgtactag cttcacatgc tcaaaaaggg
    87181 attccagcct ttgggattta tggaagagat gttcaggaag ctagtgacac agctattcca
    87241 gaagatgtca aagaaaaact tttacgttat gcgcgtgcag ctcttgcaac tggcttgatg
    87301 agagacactg cttacctatc aatgggtagt gtttcgatgg ggattggtgg ttctattgta
    87361 aatccagatt tcttccaaga atacttagga atgcgaaatg aatcggtaga tatgacggag
    87421 ttcacgcgcc gtatggaccg tggtatttat gacccagaag agttcgaacg tgctatggtt
    87481 tgggtaaaag aacatatcaa agaaggggtt gaccgaaatc gtgaggattt gattctttct
    87541 aaagaagaga aagaaaaaca atgggaattt gttattaaga tgttcatgat tggacgtgac
    87601 ttaatggttg gtaacccaag acttgctgaa cttggttttg aggaagaagc agttggtcac
    87661 catgctttag tagctggttt ccaaggtcaa cgtcagtgga cagaccattt tccaaatgga
    87721 gattttatgg aaactttcct caatactcag tttgactgga atggtattcg aaaaccattt
    87781 gtatttgcga cagagaatga ttcactaaat ggtgtgtcta tgctctttaa ttatctatta
    87841 acaaatactc cacaaatctt tgctgatgtg cgtacttatt ggagcccaga ggctgttaaa
    87901 cgtgtaacgg gacatacttt agagggtcgt gctgcagctg gcttcttaca tctaatcaac
    87961 tctggttctt gtacattgga tggtacaggt caagctactc gagatggcaa acctgttatg
    88021 aaaccattct gggagttgga agaaagtgaa gtgcaggcta tgcttgaaaa tacagacttc
    88081 ccaccagcaa accgcgaata cttccgtgga ggaggattct caactcgttt cttgacgaag
    88141 ggggatatgc cagtaacaat ggtacgtctc aatcttctaa aaggggttgg tccagtgcta
    88201 caaattgcag aaggttatac acttgaactt cctgaagatg ttcaccatac tttagataat
    88261 cgtacagatc caggatggcc aactacttgg tttgctccac gtttgacagg aaaaggtgct
    88321 ttcaagtctg tctatgacgt catgaataat tggggagcta atcacggagc cataacatat
    88381 ggacacattg gagcagactt gattaccttg gcttctatgt tgagaattcc tgtcaatatg
    88441 cataatgtac ctgaggaaga tatctttaga cctaaaaatt ggtccttatt tggaacagaa
    88501 gatctagaat cagcagacta tcgtgcatgt cagttgttgg gaccactgca taaataaaac
    88561 ttgtttatat aggaggtgaa cttacgtccc tcctatcctt ttaaaaagat ttgttaaaca
    88621 attcacaaat aattaaaaac gaatacaaaa agtaatataa tgatgttaaa tagatagcgc
    88681 ggaggcgcag gaggaaaatt atatggctac attttatgtt ccggcagtca accttattgg
    88741 aaaaggtgtt gtaaatgaag tgggtcctta tatcaaggaa cttggctata aaaaggcact
    88801 tttggtgaca gataagtaca tcgaaggcag tgacatttta cctaaggttt taaaaccact
    88861 ggatacagaa ggaatcgaat atgtcatctt tagcgatgta gagccaaacc ctacttgtaa
    88921 gaatgtcaca gatggggtag ctgctttgca agaacatgga tgtgatttta tcatcagtct
    88981 tggtgggggt tctccacagg atgcagctag ttgtatttct atcatggcta caaatggtgg
    89041 aaaaccacag gattatgaag ggcttcataa gtctgctaaa aaaggcttgc cagttgtggc
    89101 tatcaatact actgcaggta catcagcaga aattaccatt aactatgtga ttactgatga
    89161 agaacgcaag gttaagatgg taatggttga caagaatagc cttgctctta tctctgttaa
    89221 tgacccggaa ctcatgcttt ccaaacctaa aggcctgact gctgctactg gtatggatgc
    89281 tctgactcac gctgttgaag ctttggtaac acctggtgct tatgatgtaa ccaagaaact
    89341 gtctattggt gctattgagc ttatcaagga atatcttcct cgtgctgtag aaaatggaca
    89401 tgatattgaa gcgcgtgaag gtatggtcaa tgccatcttc cttggtggta tgagctttaa
    89461 taatgctggt cttggttatg ttcactcaat ggctcaccaa ctcggtgcag tatataattt
    89521 gccacatggt gtttgctgtg ccatgttgct accagttata gaacgtgaaa atgctaaacg
    89581 tgtaccagaa gctttccgca atgttgccaa agccttggga cttcatgtag aaggtaaatc
    89641 agatcaagaa tgtgccgatt atgcgattgc tgagattgag aagctttctg agacagtagg
    89701 tattcctaag aagctgactg aacttggtat tgaagaaaaa gatttcgact ttgaatacct
    89761 ttctaagaat gccttgattg atgcctgcgc accaggaaat ccatttatgc caaccttaga
    89821 agaaacgatt gccttttata aagagttatt ttagcaagag attggacgac aataggacaa
    89881 ttcacctcta attattgaca tttcaggaaa aatcgcagta aaaacggcac agccttcttt
    89941 aaatgtgcta taatactaga aaaatacttg tggaggttcc attatggcaa tatttttcat
    90001 gatttttctg attgtttgtg tgctcctatt ggtgatagtc acactgagta cagtttatgt
    90061 ggttcgtcag cagtcggtgg cgattattga acgctttggg aaataccaaa aggttgccaa
    90121 tagcggtatt catattcgct tgccttttgg gattgactcg attgcagcac ggattcagtt
    90181 gcgcttgttg caaagtgata ttgtggttga gactaagacc aaggacaatg tgttcgttat
    90241 gatgaatgta gcgactcagt accgtgtcaa cgagcagagc gtgacagatg cttactataa
    90301 actcatacgt ccagaatctc agattaaatc ttatatcgaa gatgctcttc gctcttctgt
    90361 tccaaaatta accttggatg aattgtttga gaaaaaagat gagattgccc ttgaagttca
    90421 acaccaagta gcagaagaaa tgaccactta cggctacatt atcgtgaaaa ccttgattac
    90481 caaggtcgaa ccagatgcag aagttaagca atccatgaat gaaatcaatg cggcgcaacg
    90541 taagcgggtt gcagcacaag aattggcgga agctgacaag attaaaattg tcactgcagc
    90601 tgaagccgaa gcagaaaaag accgccttca tggtgtgggg attgcccaac aacgtaaggc
    90661 gattgtggat ggattggcag agtctatcac cgaactcaag gaagccaatg ttggcatgac
    90721 agaagaacaa atcatgtcta tcctcttgac caaccagtat ttggatacct tgaatacctt
    90781 tgcctctaaa ggaaatcaaa ccatcttttt accaaatact ccaaatggtg tggatgatat
    90841 ccgaacacaa atcttgtcag cccttcgcgc tgagaagaaa taatagacta atactcttcg
    90901 aaaatctctt caaaccacgt cagcgtcgct ttgccgtata gatgttactg acttcgtcag
    90961 ttctatctgc aacctcaaaa cagtgttttg agctgacttc gtcagttcta tccacaacct
    91021 caaaacagtg ttttgagctg acttcgtcag tcttatctac tacctcaaaa cggtgttttg
    91081 agcaacctgt ggctagtttc ctagtttgct atttgatttt cattgagtac aaagagcttg
    91141 gcaacaggct ctttttgtat tgcgtttatt aagaaaaaca aaaaacatcg atatacattt
    91201 aactaaaaat tattgtatgt tatctccctt aattaggaat gataagggaa taactagaaa
    91261 gatttgtgaa tacaaactat ttctgatata caaaatatac agtaataatg aatgatggga
    91321 gatgggatga aagaatttca atttgagaga aagcagcgtt tttctttgag gaaatatgca
    91381 ataggagctt gttcggtctt gctaggaacg agtttatttt tttgctggta tgggtgctca
    91441 gcctgtacag gatacagaaa cgagttcagc actaatttca agtcattatt tggatgagca
    91501 ggatttatct gaaaagctga aatctgagtt gcaatggttt gaattagaaa acaagctttt
    91561 gaacttatgg gagcattagg ttactatgaa ggatttgttc cttatgtttc aaatcaatac
    91621 aaaaaccaag ctgaagaaga aggcaaaccg ctatctgata aatatatttt cgaaaaaatc
    91681 ttaggaaaaa catatgcagc cttcaaaaaa gatcaaatta atgagcgtgt cgagaaatta
    91741 ggtaagttaa aacctattac aataaattac aacggaaaat cagaagtaat tgatagtaaa
    91801 gaaaaattac aagagcttat gaataaagcc gttaaagacg aagtggctca aatatagtaa
    91861 aatgaaataa gaacaggaca aatcaatcag gacagtcaaa ttgatttcta aaaatgtttt
    91921 agaagtagag gtgtactatt ctagtttcaa catactataa aatcaggcaa tacaacggct
    91981 aaaaagtttg agtttatcga aataccagtg caaaaactga aaaaagcgat ttataaagct
    92041 catctcaaag attcagatga ctttagacca gaaacatcca caccaaatct ttttgaaagc
    92101 tgtttgaagc tttgtccttg ctttcttagt tcatagatct gaactttatc ttcataactc
    92161 aatttcataa taaaacaccc caaaagttag atttattctg tctaactttt ggggtgcagt
    92221 tcattaatcg gtcgattttt ttgtagaaac agttgcctga ttaagttgca agtcgataga
    92281 cggcttcggc ataaatatcc atagcacggt acaaatcttc tagaacggca cattcatttg
    92341 cctgatgttc tgtctgcttc gctcctggga ataaggcgcc gaaggctaca caatttggca
    92401 tggtgcgagc aaaagtggca ccaccggatg aaatagcagg actgttatcg ccagtctttt
    92461 cttggtagat ttgcatcagt gtgctaacga gtttactgtc ttttgcgacg tatagaggcg
    92521 ctagatagtc aaactcttcg tagcggagtt ggtagttttg tgcacatctt gtaagcaact
    92581 ctactagttc ttccttgtca gctaagacag gagtccgaat gtcaatacgg atttcagaac
    92641 gttcatgatt gatcatgaga cctgcgacat taaaggatag gtgaccagaa ggttcatctg
    92701 ctatatcacc aaagatttgt cttcctgtgc cgtcttgacc tgcttgtgtt gcaagaaaac
    92761 tgagagcagg gtgttcttgg agaggagcaa gaatggtagc tagtcggatg acagcattga
    92821 taccttgact agcatcctta gcatgctttg gcactccgag aaccgttacg gtttgttcag
    92881 tggtttggta atcataacca gcttctttga gaccgttaca aacctgttca tagaggagac
    92941 cttggtagtt ggccttgtct ggtacaacgt taaaggcgcc tcctacttca agctctagtt
    93001 gatccgatcc cgggccatga agtttgacct gtagaagccc tttttcagca taggtcagag
    93061 gaaaagatga gtcaggtgca aagcccatac tggcctgttc ttcgatggta ttgtagcgtg
    93121 ccatgcagcg ccagagggtt tcctcatcgg taccaaagat aaagcgtacg cgctttttga
    93181 actgaatacc ttggtccagc aagcttttta ctgcatagag agctgcgagc gaagggcctt
    93241 tatcatcttg gacaccacgt ccgaataccc agccgtcttt gatagttgct tcaaatggcg
    93301 gtgtctgcca atctgcttca tcacctgatg gaacaacatc caaatgacag agaatggcca
    93361 gaagctctgc tccctgaccg atttctgcat atccgtaata acctttaggg tcaagatagg
    93421 tagtgaaacc tatgtctcga caaatctcta aagttttttc taggacatct tggattgctt
    93481 gtccaaaagg tgttccattt tctccttcat tgagtactga aggataggaa atcaaggttt
    93541 ttaatgatat aagaaattca tctttaactt gatttgttat atctattttc atggaatcac
    93601 ctcactcact attttatagg aatggaagga aggttccaag gagaagaagg gcgatggtca
    93661 ctacaataat agcgactacg agtttgccca tgaatttcca ccaagtacca atgttgatac
    93721 gtccaagtgc aagagctccc atcacaatac cagatgttgg tgcaatcaag ttcaagacac
    93781 ctgaagcaga ttggtaagca gtgataatca agctaggacg gacatttaca aattctccaa
    93841 gtggagccat gatacccata gttgcgctgg caagaccaga tgaagatggg atcaagaatg
    93901 acataggtag atagaagata taagttacaa cgataaagac ttgtgaagat agaccgctca
    93961 agccttcttt accccagttg aggattgtat cggtaatcat accgtcgttc atgataactt
    94021 gaataccacg agcaatcgct acgatcaagg caacactgag caagtcagca gcaccattca
    94081 tgaaggaaga gataatctta tcttctttaa gaccataaat aacaccaatc aggataccca
    94141 taaaggcaaa gagcatggcg ccttctggga agtaccaagt acctagtgca gaagtagatg
    94201 aaccgacaat attaccaata actggaagac cagtcaacca agcattaaag tcatcaaaaa
    94261 tggtaacgcc aaggtctgtc catggaatga agctcaatac catcaagatg aatgtcaaca
    94321 caaataagaa gagaactgat ttttgtttgc tgctaagtgt agattctaca gatgaagatt
    94381 cttctacgtt aaagtgtttc aaatcttctt tgcgagtact ataaaccagt gacttagtcg
    94441 gatctttttg aatcttatcc gcataacggt aaacaaacca agtactaaga gcagtcaagg
    94501 taacccagaa aatcagacga agtacgatac cgtcccctgt accaactccc gcagtcgctg
    94561 aagcaatacc tgtcgcaaat ggattcagag tagatgccaa acagccgatt tgagaaccga
    94621 gcaaaataat tgcaacacca gtcaggctat caaaaccaac ggccatcata actggcacaa
    94681 ggagtggata gaaggccatt gtttcttccc ccataccata agttgtacca ccgagggcaa
    94741 acaaaggcat cagtaccaaa attaacattt tttcgcggcc cttatacttc ttcacgatag
    94801 aggcaatccc tacgtcaaga gcaccagttt tgttgacaat gccaaggaaa ccaccaacca
    94861 taaggatgaa gaaggctaca tcaatcgctg cgctcgtttc tttaatgagc gaaccttcct
    94921 ctggatgagt acctagcata gcccgaatcg gtgccatgag gacatcccaa atcccttgtg
    94981 gattttgagg ctgagcctcg taaatacctt ctataaaggc ccccgcaggg ataaaccaag
    95041 ttagcactgc cataatagca atgattatca ataatacggt gtaagatgaa ggcatcttaa
    95101 accctttttt agctttttca ctcatttgtt tttcctcctg atgtctaaca aagtgtaaaa
    95161 aaccaactac tttcttaaat aaacattcaa gaaaacgctt tctatttata tttgttttac
    95221 catattaaag tctaaaaaac taatatcttt tgaaatattg tacatgtttt caagaataat
    95281 ttctaatttg atataaagat actagaaata gaatacatct tattagtaaa acaacttatc
    95341 ctttttcaat aattgttccg ctttcagatt caatcaaggc gcctagattt tcaagggaag
    95401 taataactgc ttttccttct ggacgaccat tgacaaaagc gatagctgct tctacttttg
    95461 gaagcatgct acctggtgca aactgatctt gtttgatata ttcttccagc tgggcaacat
    95521 tcacatgttc caatttttcc tggtttggct tgttgtagtt aacaaataca taatctacac
    95581 ctgtcaaaat gatgaagagg tctgcatcaa ccaattctgc caaacgttgg gaagcgaagt
    95641 ctttatcaat aaccgcttcg acaccagtca aatgtccatt gttttctttg acgacgggaa
    95701 taccgccacc acctgcagct acgacgactt gaccattatt taaaagagta cggatggttt
    95761 caatttcttt gatgtcaaca ggttttggtg aggcaacgac cttacgccag ccacggccag
    95821 catcttcctt gaaagtcgct ccgctttttt cggcttctgc ttttgcttct tcttctgaat
    95881 agaaaggacc gattggttta ctcaagttaa caaaagctgg atcattttta tctacgacaa
    95941 cttgcgttac aacagaggca acattttttt cgatgccttc atccaagaga gcattttgca
    96001 aagcattttt caaccagaaa ccgatgctac cttctgtcat agcgacaagt gagtcgagtg
    96061 ggaaggcagg gttcttttca gagtctgatg ccaaatgttg gagcaagaga ttcccaactt
    96121 gaggtccatt accgtgagtg ataatcaaat catctccatt tttaatcaat tttacaagat
    96181 gcttagctgt ttcaactaaa gcttcttgtt gagcctttgc tgatgggtca gaagaaagaa
    96241 tcgcatttcc tcccaaagct actacaattt tacgatttgc cataaattct cctttatcac
    96301 actcaataga atgcgtttag atttcaattt aatgattttt cacatatttt ataagaaata
    96361 atagattacc attacataaa agaggaccgg actaaagcta ttagtcgcag ccctcatagc
    96421 tgttggtaga cggtttatta tctaaaatta tactttagga atataaaggt taccaagtgt
    96481 cgcagccata acagctttga tagtgtgcat acggttttct gcttgatcga agtggcgagc
    96541 gtacttgctg cggaagactt cgtctgttac ttccatttct tctacaccaa atttttcagc
    96601 aacgtcttta ccataaacag tgtgagtatc gtggaatgct ggcaagcagt gtaggaagat
    96661 caagttttca ttgcctgctt ttttaactaa gtccatattg acttggtaag gtttaagaag
    96721 agctacacgt tctgcgaatt tgtcttcttc acccattgat acccaaacgt ctgtgtaaag
    96781 aacgtctgca tctttaactg cttcatcagc atcttcagtg atgagaacat gtgcgccact
    96841 ttctttagca aatccttctg ccaattcaac gatttctttt tctgggaaga gttcttttgg
    96901 tgagaagatg tgaacattga caccaaggat agcacctgtt acgagcaagc tgttggcaac
    96961 gttgttacgt ccatcaccac agtataccaa tgtcaagcct tccaagcgac cgaagttttc
    97021 ttgaacagtc aagtagtcag cgagcatttg agttgggtgc cattcgtcag ttagaccgtt
    97081 ccatactgga acgcctgaga attctgccaa ttcttcaacc atacgttggc tgaatccgcg
    97141 gaattcaatc ccgtcaaaca tacgtcccaa tactttagca gtatcttcag tagattcttt
    97201 tttacccaac tgaatatcat ttgctccgag gtattctggg tgagcaccaa ggtcgatagc
    97261 cgcagttgta aaggctgcac gagtacgagt agatgttttt tcaaatagga gagcgatatt
    97321 cttgccagca aggtagtggt gttgaatatt gcgttttttc aaatctttca agtgagctga
    97381 aagaccaata aggtattcta actctgcacg ggtaaagtct ttttctgcta agaagctgcg
    97441 tccttggaat actgaatttg tcattttatt atttcctctt tctatttttt acattttcta
    97501 ttgacgaatg ccaaacagcg attacacttc ttcacgttca aatggcatag acatacaacg
    97561 aggtccacca cggccccgaa ccaattcact tccgcgaatc ttaatcaagc gaagcccgta
    97621 ttcttccaaa atcttattgg tcacggtatt gcggtcataa acaactacca caccaggtgc
    97681 gatggtcaaa gtgttagaac cgtcgttcca ttgttcacgc gcagctgcta cgatattgcc
    97741 accaccgcaa cgaatcaaat gaactttttc tacaccaagg ttttgagcaa gaagttcagc
    97801 taagtcacct ttctcttcaa cgattttaag tttttcgttt tcgtaagtaa ctgagtaaac
    97861 gtgaaggtcg ccttcgattt ctgggtgaat agtgaacttg tcatagtcta ccatagtgaa
    97921 gacagtatcc aagtgcatga atttacggtt gttagcaaat tcaaaggcca aaactttctt
    97981 gaagccaaca tttttcttga agatgttgac caaaagtttt tcgatagaag ctgcgtctgt
    98041 acgttgagag atacctactg caaggacgtc tttagaaaga actagctcgt ctccaccttc
    98101 gatacgcgta tcttcttcac ggttgtagac caaatccact tttccgccat agattgggtg
    98161 gtatttgaag atatacttac cgtagagtgt ttcacggtta cgagtgtctg caaacatgtg
    98221 gttaagcgat acggcgtttc caattgttgc aaatgggtcg cgagtgaaat agaggtttgg
    98281 catcgggtca attgcaaatg gataatctga ttcaactaag tcagttagat ctttagcttc
    98341 gtcaggaatt tctggcaatt caactttttg aatcccagcc attgtttttt caaccaattc
    98401 ttggttgtcc ttgatgccgt gaagcaattc acgaatagca accttggttt gacgatcacg
    98461 gatgttggct tcgtctaagt attcctcgat aaattgatcg cggatttctg gagaggtcaa
    98521 tgattcagca gcgagttgtt ctaggtagag aacctcaatt ccttcatcgc gaagagcttg
    98581 ggcaaatgca tcatgttctt tttgagcatc ttccaagaaa ggaatatcat caaaaagaag
    98641 cctttcaaga tagtccggca acaagttttc taactccttg cctggacggt gcaacataac
    98701 ttttttcagt ttcccaattt ctgagaagac ctgaattgga tgagaagaca tgtattttcc
    98761 tccttaaaaa ttttgacttg gcaccatttt gggtaccgct tacatgtatg ttataacgca
    98821 attcctaggt aatgtcaatg gctataattt ctcggaaaat aatataaatt atgatgttta
    98881 gcacaa
//
LOCUS       DAVKMO010000003        79104 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVKMO010000003 DAVKMO010000000
VERSION     DAVKMO010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 79104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79104
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.003"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            272..6691
                     /locus_tag="VW361_000213"
     CDS             272..6691
                     /locus_tag="VW361_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU9743354.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSNSEDALSISDKEKV
                     AENKEKHENIYSAMETSQDFKEKKTAVIKEKEVVSKNPVIDNNTSNEEAKIKEENSNQ
                     SQGDYTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSSLKNTKVLYTYDRIF
                     NGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGQSFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLEKPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAVTTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALSSNGKKTDFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSKSKTMEGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNRTSLDQDPDLFAFNNQGVHAGSTSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQKDLKVVSREHF
                     IRGILNSKGNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEISGAGDLRGKIIEVIALDGASNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIPESKFKNLKNVKDDSLNKETAEVENNLLVDNQSIEGKSLF
                     NIHKTISTIRDFENKDLKKLIKKKYKQEDDFVNGGTRTVERDYKYDDKGNIIAYDDGT
                     DLEYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKSIEIKATK
                     YDFHSKTMTFDLYANINDIVDGLAFAGDMRLFVKDNDQKKAEIKIRMPEKIKETKSEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRALSETTIYADSRNVEDGRSTQSVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKFNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPIYKGELEKGYQFDGWKISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
     gene            7318..7794
                     /locus_tag="VW361_000214"
     CDS             7318..7794
                     /locus_tag="VW361_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9743355.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            7832..8137
                     /locus_tag="VW361_000215"
     CDS             7832..8137
                     /locus_tag="VW361_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9743356.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            8185..9660
                     /locus_tag="VW361_000216"
     CDS             8185..9660
                     /locus_tag="VW361_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU9743357.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLLIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            9686..9763
                     /locus_tag="VW361_000217"
                     /pseudo
     CDS             9686..9763
                     /locus_tag="VW361_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            9965..16666
                     /locus_tag="VW361_000218"
     CDS             9965..16666
                     /locus_tag="VW361_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU9743358.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDTKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVEEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRIYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVRADNKLGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(16914..17770)
                     /locus_tag="VW361_000219"
                     /pseudo
     CDS             complement(16914..17770)
                     /locus_tag="VW361_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(17981..18340)
                     /locus_tag="VW361_000220"
     CDS             complement(17981..18340)
                     /locus_tag="VW361_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU9743359.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRTGFL
                     LTLIMYIEMIVELFLMK"
     gene            18432..19388
                     /locus_tag="VW361_000221"
                     /pseudo
     CDS             18432..19388
                     /locus_tag="VW361_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            19372..19929
                     /locus_tag="VW361_000222"
     CDS             19372..19929
                     /locus_tag="VW361_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9743360.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            19922..20176
                     /locus_tag="VW361_000223"
     CDS             19922..20176
                     /locus_tag="VW361_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743361.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTYHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            20188..22242
                     /locus_tag="VW361_000224"
     CDS             20188..22242
                     /locus_tag="VW361_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU9743362.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            22421..23281
                     /locus_tag="VW361_000225"
     CDS             22421..23281
                     /locus_tag="VW361_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU9743363.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            23500..24210
                     /gene="ccdA2"
                     /locus_tag="VW361_000226"
     CDS             23500..24210
                     /gene="ccdA2"
                     /locus_tag="VW361_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9743364.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            24230..24796
                     /locus_tag="VW361_000227"
     CDS             24230..24796
                     /locus_tag="VW361_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU9743365.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            24807..25919
                     /gene="msrB"
                     /locus_tag="VW361_000228"
     CDS             24807..25919
                     /gene="msrB"
                     /locus_tag="VW361_000228"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9743366.1"
                     /translation="MNDKLKIFLLLGVFFLSITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKTVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            26187..26924
                     /locus_tag="VW361_000229"
     CDS             26187..26924
                     /locus_tag="VW361_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9743367.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            26921..28612
                     /locus_tag="VW361_000230"
     CDS             26921..28612
                     /locus_tag="VW361_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9743368.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRVETS"
     gene            28728..29291
                     /locus_tag="VW361_000231"
     CDS             28728..29291
                     /locus_tag="VW361_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU9743369.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            29313..34748
                     /locus_tag="VW361_000232"
     CDS             29313..34748
                     /locus_tag="VW361_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9743370.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPSPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETVNQPVEQPKVETPAVEKQTEPTEEPKVEVTSIPQTTRYEEDLTKE
                     HGTREVVKEGKNGSRTVTTPYILNATDGTTTEGTSTTDEAEMEKEVVRVGTKPKEKLA
                     PVLSLTSVTDNAMLRSARLTYHLENTDSVDVKKIHAEIKNGDKVVKTIDLSKERLSDA
                     VDGLELYKDYKIVTSMTYDRGNGEETSTLEETPLRLDLKKVELKNIGSTNLVKVNEDG
                     TEVASDFLTSKPVDVQNYYLKVTSRDNKVFRLTVEKIEEVTEEGQPLYKVTAKAPNLI
                     QHTDATKMQDEYVYYIEKTRATDGDIYYNFNDLVNAMNKNKTGTFKLGADLNATGVPT
                     PAKSYVTGDFRGTLTSVDGEHYTIHNTSRPLFNNIIGGTIKDINLGNVNIHMPWANNV
                     ASLANIIKGGTTIENVKVTGNVLGKDWVSGFIDKIDSGGTLRNVAFIGNVTSVGTGGS
                     FLTGIVGENWKGLVEQAYVDANIRGKKAKAAGIAYWSQNGGDNYAVGRYGAIKKSVVK
                     GSIDVEKPIEVGGAVGSLNYLGYIEDTVAMMKVKNGEIFYGSHDIDTDPYYTGERVNR
                     NFIVDGVSEGKSSYKYSKQQNRIKSVSQEEADKKIKELAITADKYAITEPIVNKLNAL
                     TTRDNEYRTTQDYKADRELAYRNIEKLQPFYNKEWIVDQGNKVPSNSKLLTTEVLSVT
                     GMKDGQFVTDLSEIDKIMIHYADGTKEEMNVTAVADSKVKQVREYDVTDLGVVYTPNM
                     VDKNRDQLIADVKAKLSSVELISPEVRALMDKRGKAEENTEGRQNGYIRDLFLEESFA
                     EVKAGLGKLVKALVENEDYQLNSDEAAMRALIKKVEDNKAKIMMGLTYLNQYYSFKYA
                     ELSIKDIMMFKPDFYGKNVNVLDFLIKIGSSERNVKGDRTLEAYRETIGGTIGINELN
                     GFLHYNMKLFTNHIDINDWFKKAIEKNAYVVEQPSTNPAFANKKYRLYEGINNGQHGR
                     MILPLLNLKNAHLFMISTYNTISFSSFEKYGKDTDEKREKFKSEINKRAKEQVNYLDF
                     WSRLATDNVRDKLLKSQNVVPTPVWDNHNSPNGWASRHGHIDGKPDYAPIREFFGRIN
                     KYHGYKYGYGAYAYIFAAPQPMDAVYFVMTDLISDFGTSAFTHETTHINDRMAYYGGH
                     WHREGTDLEAFAQGMLQTPSVSNPNGEYGALGLNMAYERQNDGNQWYNPNPNKLKSRA
                     EIDHYMKNYNEALMMLDYLEAESVLPKLKGNNDRWFKKMDKQMRKDGQPHQFDKIRDL
                     NNEEKKIQLASIEDLVDNNFMTKHGAPGNGTYNPSDFSSAYVNMNMMTGVYGGNSSDG
                     APGAASFKHNTFRMWGYFGYENGFIGYASNKYKAEANKAGQTLSDKYIINKVSGGTFN
                     TLEAWKKEWFKQIKTKAQKGFTAIEIDGKTIDSYEKLKDLFDKAVEEDLKGTGTDKTV
                     KLKEKVYKQLLKNTDGFSGDLFTAPQA"
     gene            34817..36538
                     /gene="pabB"
                     /locus_tag="VW361_000233"
     CDS             34817..36538
                     /gene="pabB"
                     /locus_tag="VW361_000233"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU9743371.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVAEVADLLAQVESYQ
                     EQDYYVVGYVSYEAAPAFEEKLAVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAENYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLGQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            36539..37156
                     /locus_tag="VW361_000234"
     CDS             36539..37156
                     /locus_tag="VW361_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9743372.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGATLTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            37206..38195
                     /locus_tag="VW361_000235"
     CDS             37206..38195
                     /locus_tag="VW361_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9743373.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIYEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMVQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAVNEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDH"
     gene            38330..39289
                     /locus_tag="VW361_000236"
     CDS             38330..39289
                     /locus_tag="VW361_000236"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU9743374.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            39386..40225
                     /locus_tag="VW361_000237"
     CDS             39386..40225
                     /locus_tag="VW361_000237"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU9743375.1"
                     /translation="MTKADTIFKENIECILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(40273..40443)
                     /locus_tag="VW361_000238"
     CDS             complement(40273..40443)
                     /locus_tag="VW361_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU9743376.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            40564..41448
                     /gene="miaA"
                     /locus_tag="VW361_000239"
     CDS             40564..41448
                     /gene="miaA"
                     /locus_tag="VW361_000239"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU9743377.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIKEFLDD"
     gene            41441..42679
                     /gene="hflX"
                     /locus_tag="VW361_000240"
     CDS             41441..42679
                     /gene="hflX"
                     /locus_tag="VW361_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU9743378.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            42672..43295
                     /locus_tag="VW361_000241"
     CDS             42672..43295
                     /locus_tag="VW361_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU9743379.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            43310..44239
                     /locus_tag="VW361_000242"
     CDS             43310..44239
                     /locus_tag="VW361_000242"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU9743380.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            44260..45015
                     /locus_tag="VW361_000243"
     CDS             44260..45015
                     /locus_tag="VW361_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU9743381.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(45069..45977)
                     /locus_tag="VW361_000244"
     CDS             complement(45069..45977)
                     /locus_tag="VW361_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9743382.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            46041..46310
                     /locus_tag="VW361_000245"
     CDS             46041..46310
                     /locus_tag="VW361_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU9743383.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            46310..46690
                     /locus_tag="VW361_000246"
     CDS             46310..46690
                     /locus_tag="VW361_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9743384.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNKEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            46779..47006
                     /locus_tag="VW361_000247"
     CDS             46779..47006
                     /locus_tag="VW361_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743385.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(47046..47771)
                     /locus_tag="VW361_000248"
     CDS             complement(47046..47771)
                     /locus_tag="VW361_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HEU9743386.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDSCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            47933..49774
                     /gene="typA"
                     /locus_tag="VW361_000249"
     CDS             47933..49774
                     /gene="typA"
                     /locus_tag="VW361_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU9743387.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            49794..50048
                     /locus_tag="VW361_000250"
     CDS             49794..50048
                     /locus_tag="VW361_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU9743388.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            50413..50712
                     /locus_tag="VW361_000251"
     CDS             50413..50712
                     /locus_tag="VW361_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU9743389.1"
                     /translation="MKTKKHRLLALVLISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWDGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            50783..52804
                     /locus_tag="VW361_000252"
     CDS             50783..52804
                     /locus_tag="VW361_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9743390.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMALTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLIDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            52806..53447
                     /locus_tag="VW361_000253"
     CDS             52806..53447
                     /locus_tag="VW361_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743391.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            53551..54891
                     /locus_tag="VW361_000254"
     CDS             53551..54891
                     /locus_tag="VW361_000254"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU9743392.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPGSHNV
                     ENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNILATQ
                     KALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKAGVAY
                     VEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE"
     gene            54893..55951
                     /locus_tag="VW361_000255"
     CDS             54893..55951
                     /locus_tag="VW361_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU9743393.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            55961..57160
                     /gene="divIB"
                     /locus_tag="VW361_000256"
     CDS             55961..57160
                     /gene="divIB"
                     /locus_tag="VW361_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU9743394.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     NQRSSRR"
     gene            57393..58094
                     /gene="pyrF"
                     /locus_tag="VW361_000257"
     CDS             57393..58094
                     /gene="pyrF"
                     /locus_tag="VW361_000257"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU9743395.1"
                     /translation="MREHRPIIALDFPNFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            58128..58760
                     /locus_tag="VW361_000258"
     CDS             58128..58760
                     /locus_tag="VW361_000258"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU9743396.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            58940..59343
                     /locus_tag="VW361_000259"
                     /pseudo
     CDS             58940..59343
                     /locus_tag="VW361_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            59439..60203
                     /locus_tag="VW361_000260"
     CDS             59439..60203
                     /locus_tag="VW361_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743397.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            60203..60955
                     /locus_tag="VW361_000261"
     CDS             60203..60955
                     /locus_tag="VW361_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743398.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            60965..61663
                     /locus_tag="VW361_000262"
     CDS             60965..61663
                     /locus_tag="VW361_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743399.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAIVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANEQMNFSCVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            61660..62307
                     /locus_tag="VW361_000263"
     CDS             61660..62307
                     /locus_tag="VW361_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743400.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(62394..63260)
                     /locus_tag="VW361_000264"
     CDS             complement(62394..63260)
                     /locus_tag="VW361_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9743401.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGPSSGKTTAKARTID
                     ENKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(63272..64029)
                     /locus_tag="VW361_000265"
                     /pseudo
     CDS             complement(63272..64029)
                     /locus_tag="VW361_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(64030..64707)
                     /locus_tag="VW361_000266"
     CDS             complement(64030..64707)
                     /locus_tag="VW361_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9743402.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            complement(64667..65347)
                     /locus_tag="VW361_000267"
     CDS             complement(64667..65347)
                     /locus_tag="VW361_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9743403.1"
                     /translation="MDWSIVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHY
                     RIPVLAQVATAYIELSRNTPLLIHLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMA
                     ESFRSGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVALPSFSANVIFLIKETSV
                     FSAVALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFG
                     NPSTLSGK"
     gene            65562..65708
                     /locus_tag="VW361_000268"
     CDS             65562..65708
                     /locus_tag="VW361_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU9743404.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            65835..67325
                     /gene="lysS"
                     /locus_tag="VW361_000269"
     CDS             65835..67325
                     /gene="lysS"
                     /locus_tag="VW361_000269"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU9743405.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            67950..69086
                     /gene="lctO"
                     /locus_tag="VW361_000270"
     CDS             67950..69086
                     /gene="lctO"
                     /locus_tag="VW361_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU9743406.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     regulatory      69340..69428
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            69643..70311
                     /locus_tag="VW361_000271"
     CDS             69643..70311
                     /locus_tag="VW361_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU9743407.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDFALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     gene            complement(70416..70502)
                     /locus_tag="VW361_000272"
                     /pseudo
     CDS             complement(70416..70502)
                     /locus_tag="VW361_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            70593..71375
                     /gene="thiM"
                     /locus_tag="VW361_000273"
     CDS             70593..71375
                     /gene="thiM"
                     /locus_tag="VW361_000273"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9743408.1"
                     /translation="MTSLKLLKEKVPLVICITNDVVKNFTANGLVALSVSPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            71377..72006
                     /locus_tag="VW361_000274"
     CDS             71377..72006
                     /locus_tag="VW361_000274"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9743409.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     regulatory      72215..72303
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            72565..73125
                     /locus_tag="VW361_000275"
     CDS             72565..73125
                     /locus_tag="VW361_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9743410.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSAMIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLSFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            73126..74511
                     /locus_tag="VW361_000276"
     CDS             73126..74511
                     /locus_tag="VW361_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743411.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHVQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIARKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTSIVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            74513..75163
                     /locus_tag="VW361_000277"
     CDS             74513..75163
                     /locus_tag="VW361_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU9743412.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQFKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            75174..75866
                     /gene="tenA"
                     /locus_tag="VW361_000278"
     CDS             75174..75866
                     /gene="tenA"
                     /locus_tag="VW361_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU9743413.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            75871..76395
                     /gene="thiW"
                     /locus_tag="VW361_000279"
     CDS             75871..76395
                     /gene="thiW"
                     /locus_tag="VW361_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU9743414.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            76395..77198
                     /locus_tag="VW361_000280"
     CDS             76395..77198
                     /locus_tag="VW361_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9743415.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAALYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            77191..77823
                     /locus_tag="VW361_000281"
     CDS             77191..77823
                     /locus_tag="VW361_000281"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9743416.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(78032..78823)
                     /gene="thiD"
                     /locus_tag="VW361_000282"
     CDS             complement(78032..78823)
                     /gene="thiD"
                     /locus_tag="VW361_000282"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9743417.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(78907..79005)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
BASE COUNT        24579 a        14161 c        17202 g        23162 t
ORIGIN      
        1 acctgcggct agtttcctag tttgctcttt gattttcatt gagtactaat cttatttttt
       61 aacgtgtgct aaaaaataaa ttaatgcatg ttaatttttc ttgaattaaa tttttttaaa
      121 tgatatactg tttttatgga gagataacaa ttatatataa atgtactact ctatttccta
      181 gataatactt agtaaaactt tttataacaa aggctagcaa agttaaagtt tattatctat
      241 tggagtttaa ataaatatgt aaggaattaa aatgaaaaaa agtacagtat tgtcattaac
      301 cacagctgca gttattttag cagcctatgc ccctaatgag gtagtcttag cagacacatc
      361 taactctgaa gatgctttaa gcatctctga taaagaaaaa gtagcagaaa ataaagagaa
      421 acatgaaaat atctatagtg ctatggaaac ttcacaggat tttaaagaga agaaaacagc
      481 agtcattaag gaaaaagaag ttgttagtaa aaatcctgtg atagacaata acactagcaa
      541 tgaagaagca aaaatcaaag aagaaaattc caatcaatcc caaggagatt atacggactc
      601 atttgtgaat aaaaacacag aaaatcccaa aaaagaagat aaagttgtct atattgctga
      661 atttaaagat aaagaatctg gagaaaaagc aatcaagcaa ctatccagtc ttaagaatac
      721 aaaagtttta tatacttatg atagaatttt taacggtagt gccatagaaa caactccaga
      781 taacttggac aaaattaaac aaatagaagg tatttcatcg gttgaaaggg cacaaaaagt
      841 ccaacccatg atgaatcatg ccagaaagga aattggagtt gaggaagcta ttgattacct
      901 aaagtctatc aatgctccgt ttgggaaaaa ttttgatggt agaggtatgg tcatttcaaa
      961 tatcgatact ggaacagatt atagacataa ggctatgaga atcgatgatg atgccaaagc
     1021 ctcaatgaga tttaaaaaag aagacttaaa aggaactgat aaaaattatt ggttgagtga
     1081 taaaatccct catgcgttca attattataa tggtggcaaa atcactgtag aaaaatatga
     1141 tgatggaaga gattattttg acccacatgg gatgcatatt gcagggattc ttgctggaaa
     1201 tgatactgaa caagatatca aaaactttaa cggcatagat ggaattgcac ctaatgcaca
     1261 aattttctct tacaaaatgt attctgacgc aggatctggg tttgcgggtg atgaaacaat
     1321 gtttcatgct attgaagatt ctatcaaaca caacgttgat gttgtttcgg tatcatctgg
     1381 ttttacagga acaggtcttg taggtgagaa atattggcaa gctattcggg cattaagaaa
     1441 agcaggcatt ccaatggttg tcgctacggg taactatgcg acttctgctt caagttcttc
     1501 atgggattta gtagcaaata atcatctgaa aatgaccgac actggaaatg taacacgaac
     1561 tgcagcacat gaagatgcga tagcggtcgc ttctgctaaa aatcaaacag ttgagtttga
     1621 taaggttaac attggaggac aaagttttaa atacagaaat ataggggcct ttttcgataa
     1681 gaataaaatc acaacaaatg aagatggaac aaaagctcct agtaaattaa aatttgtata
     1741 tataggcaag gggcaagacc aagatttgat aggtttggat cttaggggca aaattgcagt
     1801 aatggataga atttatacaa aggatttaaa aaatgctttt aaaaaagcta tggataaggg
     1861 tgcacgcgcc attatggttg taaatactgt aaattactac aatagagata attggacaga
     1921 gcttccagct atgggatatg aagcggatga aggtactaaa agtcaagtgt tttcaatttc
     1981 aggagatgat ggtgtaaagc tatggaacat gattaatcct gataaaaaaa ctgaagtcaa
     2041 aagaaataat aaagaagatt ttaaagataa attggagcaa tactatccaa ttgatatgga
     2101 aagttttaat tccaacaaac cgaatgtagg tgacgaaaaa gagattgact ttaagtttgc
     2161 acctgacaca gacaaagaac tctataaaga agatatcatc gttccagcag gatccacatc
     2221 ttgggggcca agaatagatt tacttttaaa acccgatgtt tcagcacctg gtaaaaatat
     2281 taaatccacg cttaatgtta ttaatggcaa atcaacttat ggctatatgt ccggaactag
     2341 tatggcgact ccaatcgtag cagcttctac tgttttgatt cgaccaaaat tgaaggaaat
     2401 gcttgaaaaa cccgtattaa aaaatcttaa aggtgatgat aaaatagacc ttacaagtct
     2461 tacaaaaata gccctacaaa atactgcaag acctatgatg gatgcaactt cttggaaaga
     2521 aaaaagtcaa tactttgcat cacctagaca gcagggggcg gggctaatta atgtggccaa
     2581 cgctttgaga aatgaagttg tagcgacttt caaaaacacg gattctaaag gtttggtaaa
     2641 ttcatatggt tccatttctc ttaaagaaat aaaaggtgat aaaaaatact ttacaattaa
     2701 gcttcacaat acatccaaca ggcctttaac ctttaaagtt tcagcatcag cggtaactac
     2761 agattctcta actgacagac taaaactgga tgaaacatat aaagatgaaa aatctccaga
     2821 tggtaagcaa attgttccag aaattcatcc agaaaaagtc aaaggggcaa atattacatt
     2881 tgagcatgac actttcacta taggggcaaa ttctagcttt gatttaaatg cggttataaa
     2941 tgttggggag gctaaaaata aaaataaatt tgtagaatca tttattcatt ttgagtcagt
     3001 agaagaaatg gaagcattaa gctccaatgg caagaaaacc gacttccaac catctttatc
     3061 aatgcccctg atgggatttg ctgggaattg gaaccacgaa ccaatccttg ataaatgggc
     3121 ttgggaagaa ggatcaaaat caaaaacaat ggaaggttat gatgatgacg gtaaaccaaa
     3181 aattccagga accttaaata aggggattgg tggagaacat ggtatagata aatttaatcc
     3241 agcaggagtt atccaaaata gaaaagataa aaatagaaca tctctagatc aagatccaga
     3301 cttatttgcc tttaacaacc aaggtgttca tgcaggatcc actagtggtt ctaagattgc
     3361 taacatttat cctttagatt caaatggaaa tcctcaagat gctcaactag aaagaggact
     3421 aactccatct ccacttgttc taagaagtgc agaagaagga ctaatttcaa ttgtaaacac
     3481 caacaaagaa ggagaaaacc aaaaagacct taaagttgta tcaagagagc acttcataag
     3541 aggaattcta aattctaagg gaaatgacgc taagggtatc aaatcatcca aactaaaagt
     3601 ttggggtgac ttgaaatggg atggactcat ctataaccca agaggtagag aagaaaatgc
     3661 cccagaaagt aaggataacc aagatccagc tactaagata cgaggacaat ttgaaccgat
     3721 tgcggaaggt caatatttct ataaatttaa atatagatta actaaagatt acccatggca
     3781 ggtttcctat attcctgtaa aaattgataa cacagcccct aagattgttt cggttgattt
     3841 ttcaaatcct gaaaaaatta agctaatcac aaaggatact tatcacaagg taaaagatca
     3901 atacaagaat gaaactttat ttgctagaga tcaaaaagaa catcctgaaa aatttgatga
     3961 gattgcaaat gaggtgtggt atgcaggagc tgctcttgtt aatgaagatg gagaggttga
     4021 gaaaaatctt gaagtaactt atgcaggtga gggtcaagga agaaatagga agcttgataa
     4081 agatgggaat actatctatg aaattagcgg agcaggagat ctaagaggaa aaatcatcga
     4141 agtaatcgcc ctagatggag caagcaactt taccaaaatc cataggatta aatttgctaa
     4201 tcaagctgat gaaaaaggga tgatttccta ttatctagta gatcctgatc aggattcatc
     4261 taaataccaa aagcttggcg aaattcctga atctaaattt aagaatttaa aaaatgttaa
     4321 agatgatagc ctaaacaaag agacagctga ggtggaaaat aaccttttag tagataatca
     4381 gtctatcgaa ggaaaatctc tctttaatat tcataaaact atttcaacaa ttagagactt
     4441 tgaaaataaa gacctaaaga aactcattaa aaagaaatat aagcaagaag acgactttgt
     4501 aaatggtgga acaagaacag tagagcgtga ttataaatac gatgataaag gaaatataat
     4561 agcctacgat gatgggactg atctagaata tgaaactgag aaacttgacg aaatcaaatc
     4621 aaaaatttat ggtgttctaa gtccgtctaa agatggacac tttgaaattc ttggaaagat
     4681 aagtaatgtt tctaaaaatg ccaaggtata ttatgggaat aactataaat ctatagaaat
     4741 caaagcgacc aagtatgatt tccactcaaa aacgatgaca tttgatctat acgctaatat
     4801 taatgatatt gtggatggat tagcttttgc aggagatatg agattatttg ttaaagataa
     4861 tgatcagaaa aaagctgaaa ttaaaattag aatgcctgaa aaaattaagg aaactaaatc
     4921 agaatatccc tatgtatcaa gttatgggaa tgtcatagaa ttaggggaag gagatctttc
     4981 aaaaaacaaa ccagacaatt taactaaaat ggaatctggt aaaatctatt ctgattcaga
     5041 aaaacaacaa tatctgttaa aggataatat cattctaaga aaaggctatg cactaaaagt
     5101 gactacctat aatcctggaa aaacggatat gttagaagga aatggagtct atagcaagga
     5161 agatatagca aaaatacaaa aggccaatcc taatctaaga gccctttcag aaacaacaat
     5221 ttatgctgat agtagaaatg ttgaagatgg aagaagtacc caatctgtat taatgtcggc
     5281 tttggacggc tttaacatta taaggtatca agtgtttaca tttaaaatga acgataaagg
     5341 ggaagctatc gataaagacg gaaatcttgt gacagattct tctaaacttg tattatttgg
     5401 taaagatgat aaagaataca ctggagagga taagttcaat gtagaagcta taaaagaaga
     5461 tggctccatg ttatttattg ataccaaacc agtaaacctt tcaatggata agaactactt
     5521 taatccatct aaatctaata aaatttatgt acgaaatcca gaattttatt taagaggtaa
     5581 gatttctgat aagggtggtt ttaactggga attgagagtt aatgaatcgg ttgtagataa
     5641 ttatttaatc tacggagatt tacacattga taacactaga gattttaata ttaagctgaa
     5701 tgttaaagac ggtgacatca tggactgggg aatgaaagac tataaagcaa acggatttcc
     5761 agataaggta acagatatgg atggaaatgt ttatcttcaa actggctata gtgatttgaa
     5821 tgctaaagca gttggagtcc actatcagtt tttatatgat aatgttaaac ccgaagtaaa
     5881 cattgatcct aagggaaata ctagtatcga atatgctgat ggaaaatctg tagtctttaa
     5941 catcaatgat aaaagaaata atggattcga tggtgagatt caagaacaac atatttatgt
     6001 aaatggaaaa gaatatacat catttgatga tattaaacaa ataacagaca agacactaaa
     6061 cattaagatt gttgtaaaag attttgcaag aaatacaacc gtaaaagaat tcattttaaa
     6121 taaagatacg ggagaggtaa gtgaattaaa acctcatagg gtaactgtga ccattcaaaa
     6181 tggaaaagaa atgagttcaa cgatagtgtc ggaagaagat tttattttac ctatttataa
     6241 gggtgaatta gaaaaaggat accaatttga tggttggaaa atttctggtt tcgaaggtaa
     6301 aaaagacgct ggctatgtta ttaatctatc aaaagatacc tttataaaac ctgtattcaa
     6361 gaaaatagag gagaaaaagg aggaagaaaa taaacctact tttgatgtat cgaaaaagaa
     6421 agataaccca caagtaaacc atagtcaatt aaatgaaagt cacagaaaag aggatttaca
     6481 aagagaagat cattcacaaa aatctgattc aactaaggat gttacagcta cagttcttga
     6541 taaaaacaat atcagtagta aatcaactac taacaatcct aataagttgc caaaaactgg
     6601 aacagcaagc ggagcccaga cactattagc tgccggaata atgtttatag taggaatttt
     6661 tcttggattg aagaaaaaaa atcaagatta agacaaaagc tatagaaaaa aatggtttat
     6721 gtactgagat tagatagtga ggtgatgaca tagttttgtg aaaacagcca tttataactc
     6781 aattatttag cttacttcac tattgatact atttggagtt attaatggac ttagtttaga
     6841 taactaatga attgattgaa agggttagta ttgacaatat tggtcatatt gattagaaaa
     6901 tagagtctat caaaatttaa aggctaatag aggtgatgag acaatttcaa ggaattaagt
     6961 agcgtttggt tgcttaattc ctttttattt ggaaggaagt ttttcgtaac cgcccaataa
     7021 cgaagtctat tgggcggtta cgatatgatc actgacttcg tcagttctat ctacaaccta
     7081 aaaacagtgt tttgaacaac ctgcggctag cttcctagtt tgctctttga ttttcattga
     7141 atattagaac agcaaaaatg cttggagtat ttgtttgtgt gtttgttttt atataacaaa
     7201 ctataaacaa aacaaaaata taaaaaaaga gacaaaaaag aacaaaaagt aattgacaac
     7261 ggtttcatat agtgttatac ttatggcata aagttaatgg aaagaaggga aaaccttatg
     7321 gtattagatt atttctttga caaaaacctt gtgttttgct tagaagcgga taatcaagaa
     7381 caactctttg atcaggttgc aactttattg gaagaacgag aaattgtcac tccaacttat
     7441 cgtgaagcct tgatcacgcg tgaaaagtca tttccaactg gtttagatat ggaatttcta
     7501 ggaaaggact tgccaaatgt agcgattcct catacagata ttgttcataa tctagctgag
     7561 aaagtggtgg ttgttcgatt agaaaaacca gtaacttttc acaatatgat agctcctgat
     7621 aaggaagtag aagtatcctt gctcttcttt atcatcaata actcaagttc aagtcaaaca
     7681 aatattctgg ctcagttgat ggactttttc acaggaaatg gacatcttga agacctatca
     7741 aaaatttccg aaccagaaaa actttatgct tacattgctg aagcaaccgc ttaatcttgt
     7801 ctattaaaaa ataaaatcgg aggaaatcta aatgattaaa attcttgctg cctgcggtgc
     7861 aggtgttaac tcaagtcacc aaattaaaag tgctctagaa gaagaacttt caaaccgtgg
     7921 ttatgatgtt cactgtgatg cagtcatggt gaaagatgta aacgaagacc ttatgaaagg
     7981 ttacgatatc tttacaccaa tcgctgcaac agaccttggt tttgaaccag gtatcccagt
     8041 tatcgaagct ggaccaatct tattccgtat cccagcaatg agcgctccag tatttgacaa
     8101 tattgaagca gctattaaag aacacggatt aagctaattc taatttgtta acattcatat
     8161 aacataaaaa agggaggaac tgttatggat gcaatctttg acctaatcgg aaaggttttc
     8221 aatcccatct tagaaatggg tggacctgtc atcatgttaa tcattttgac agtattggct
     8281 ttactttttg gagtgaaatt ctccaaagcg cttgaaggtg gtatcaaact tgccatcgct
     8341 cttacaggta tcggtgctat catcggtatg ctaaatggtg ctttctcagc atcacttgca
     8401 aaattcgttg aaaacactgg tatacaattg agtattaccg acgttggttg ggcaccactt
     8461 gcaacaatca cttggggttc tgcttggaca ctttacttct tgctcatcat gttgattgtc
     8521 aacgtagtga tgcttgctat gaagaaaacc gatacacttg atgtcgatat ctttgatatc
     8581 tggcacttgt ctatcacagg tctcttgatt aaatggtatg ctgataacaa tggtgtgagt
     8641 caaggggttt cactcttgat tgctacagca gctatcgttc ttgtcggtgt gttgaaaatt
     8701 atcaactctg acttgatgaa acctacattt gatgaccttc ttaacgcccc aagttcatca
     8761 ccaatgacat caactcacat gaactacatg atgaacccag ttatcatggt tttggataag
     8821 atttttgaaa aattcttccc aggccttgat aaatatgact ttgatgctgc taaattgaac
     8881 aagaaaatcg gtttctgggg atctaaattc ttcatcggtt tcatccttgg tatcgttatc
     8941 ggtattatgg gaactccaca tccaattgca ggtgttgcag atgcagataa atggcgtctt
     9001 gttatcaaag gatggttgtc tcttggtttg actgccggtg tatctttgga actcttctca
     9061 cttatcggtt catggttcat cgcagccgta gaaccactat cacaaggtat tacaaacgtt
     9121 gctactaaac gtcttcaagg acgtaaattc aatatcggtc ttgactggcc attcatcgct
     9181 ggtcgtgctg aaatctgggc ttgtgccaac gtacttgcac caatcatgtt gattgaagca
     9241 gtgcttcttt caaaagttgg aaatggtatc ttgccacttg caggtatcat cgctatgggt
     9301 gttactccag ctctcttggt tgtaactcgt ggtaaattgc tccgtatgat tatcttcgga
     9361 acactcttgt tgccactctt ccttctttca ggtaccctta ttgcaccatt tgcaacagaa
     9421 cttgctaaag gtgtaggtgc cttcccagaa ggtgtgagcc aaactcaatt gattactcac
     9481 tctactcttg aaggaccaat cgaaaaactt cttggttgga caattggtaa cactacaact
     9541 ggtgatatca aagcaatcct tggtgcagta gccttccttg tattctatat cggtatcttt
     9601 gcttggtaca gaaaacaaat gatcaaacgt aacgaagagt acgcagcaaa agcaaaataa
     9661 tgcgctccta taaaatataa actcaatgaa aatcaaagag caaactagga agctagccgc
     9721 aggttgctca aaacacagtt ttgaggttgt agataagact gacgaagtca gctcaaaaca
     9781 tggttttgag gttgtagatg aaactgacga agtcagtaat catatctacg gcaaggcgac
     9841 actgacgaag tttgaattgg attttcgcag agtgtaaatt gttgaaacta ggttgtcata
     9901 ccatgtatac cacttgggct ttggtagtag ctaactgcac taaatataat ataaggaggg
     9961 ttttatgggg aaaggccatt ggaatcggaa aagagtttat agcattcgta agtttgctgt
    10021 gggagcttgc tcagtaatga ttgggacttg tgcagttcta ttaggaggaa atatagctgg
    10081 agaatctgta gtttatgcgg atgaaacact tattactcat actgctgaga aacctaaaga
    10141 ggaaaaaatg atagtagaag aaaaggctga taaagctttg gaaactaaaa atgtagttga
    10201 aaggacagaa caaagtgaac ctagttcaac tgaggctatt gcatctgaga agaaagaaga
    10261 tgaagccgta actccaaaag aggaaaaagt gtctgctaaa ccggaagaaa aagctccaag
    10321 gatagaatca caagcttcaa gtcaagaaaa accgctcaag gaagatacta aagctgtaac
    10381 aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg gattttaatc aaaattggta
    10441 ctttaaactc aatgcaaatt ctaaggaagc cattaaacct gatgcagacg tatctacgtg
    10501 gaaaaaatta gatttaccgt atgactggag tatctttaac gatttcgatc atgaatctcc
    10561 tgcacaaaat gaaggtggac agctcaacgg tggggaagct tggtatcgca agactttcaa
    10621 actagatgaa aaagacctca agaaaaatgt tcgccttact tttgatggcg tctacatgga
    10681 ttctcaagtt tatgtcaatg gtcagttagt ggggcattat ccaaatggtt ataaccagtt
    10741 ctcatacgat atcaccaaat accttcacaa agatggtcgt gagaatgtga ttgctgtcca
    10801 tgcagtcaac aaacagccaa gtagccgttg gtattcagga agtggtatct atcgtgatgt
    10861 gactttacaa gtgacagata aggtgcatgt tgagaaaaat gggacaacta ttttaacacc
    10921 aaaacttgaa gaacaacaac atggcaaggt tgaaactcat gtgaccagca aaatcgtcaa
    10981 tacggacgac aaagaccatg aacttgtagc cgaatatcaa atcgttgaac gaggtggtca
    11041 tgctgtaaca ggcttagttc gtacagcgag tcgtacctta aaagcacatg aatcaacaag
    11101 cctagatgcg attttagaag ttgaaagacc aaaactctgg accgttttaa atgacaaacc
    11161 tgccttgtac gaattgatta cgcgtgttta ccgtgacggt caattggttg atgctaagaa
    11221 ggatttgttt ggttaccgtt actatcactg gactccaaat gaaggtttct ctttgaatgg
    11281 tgaacgtatt aaattccatg gagtatcctt gcaccacgac catggggcgc ttggagcaga
    11341 agaaaactat aaagcagaat atcgccgtct caaacaaatg aaggagatgg gagttaactc
    11401 catccgtaca acccacaacc ctgctagtga gcaaaccttg caaatcgcag cagaactagg
    11461 tttactcgtt caggaagagg cttttgatac ttggtatggt ggcaagaaac cttatgacta
    11521 tggacgtttt tttgaaaaag atgccactca cccagaagct cgaaaaggtg aaaaatggtc
    11581 tgattttgac ctacgtacca tggtcgaaag aggcaaaaac aaccctgcta tcttcatgtg
    11641 gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc cactctttag caactgttaa
    11701 acgtttggtc aaggttatca aggatgttga taagactcgc tatgttacca tgggagcaga
    11761 taaattccgt ttcggtaatg gtagcggagg gcatgagaaa attgctgatg aactcgatgc
    11821 tgttggattt aactattctg aagataatta caaagccctt agagctaagc atccaaaatg
    11881 gttgatttac ggttcagaaa catcatcagc aacccgtaca cgaggaagtt actatcgccc
    11941 tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat tatgaacagt cagattatgg
    12001 aaatgatcgt gttggttggg ggaaaacagc aaccgcttca tggacttttg accgtgacaa
    12061 cgctggctat gctggacagt ttatctggac aggtacggac tatattggtg aacctacacc
    12121 atggcacaac caaaatcaaa ctcctgttaa gagctcttac tttggtatcg tagatacagc
    12181 cggcattcca aaacatgact tctacctcta ccaaagccaa tgggtttctg ttaaaaagaa
    12241 accgatggta caccttcttc ctcactggaa ctgggaaaac aaagaattag catccaaagt
    12301 agctgactca gaaggtaaga ttccagttcg tgcttattcg aatgcttcta gtgtagaatt
    12361 gttcttgaat ggaaaatctc ttggtcttaa gactttcaat aaaaaacaaa ccagcgatgg
    12421 gcggacttac caagaaggtg caaatgctaa tgaactttat cttgaatgga aagttgccta
    12481 tcaaccgggt accttggaag caattgctcg tgatgaatct ggcaaggaaa ttgctcgaga
    12541 taagattacg actgctggta agccagcggc agttcgtctt attaaggaag accatgcgat
    12601 tgcagcagat ggaaaagact tgacttacat ctactatgaa attgttgaca gccaggggaa
    12661 tgtggttcca actgctaata atctggttcg cttccaattg catggccaag gtcaactggt
    12721 cggtgtagat aacggagaac aagccagtcg tgaacgctat aaggcgcaag cagatggttc
    12781 ttggattcgt aaagcattta atggtaaagg tgttgccatt gtcaaatcaa ctgaacaagc
    12841 agggaaattc acccttactg cccactctga tctcttgaaa tcgaaccaag tcactgtctt
    12901 tactggtaag aaagaaggac aagagaagac tgttttgggg acagaagtgc caaaagtaca
    12961 gaccattatt ggagaggcac ctgaaatgcc taccactgtt ccgtttgtat acagtgatgg
    13021 tagccgtgca gaacgtcctg taacctggtc ttcagtagat gtgagcaagc ctggtattgt
    13081 aacggtgaaa ggtatggctg acggacgaga agtagaagct cgtgtagaag tgattgctct
    13141 taaatcagag ctaccagttg tgaaacgtat tgctccaaat actgacttga attctgtaga
    13201 caaatctgtt tcctatgttt tgactgatgg aagtgttgaa gagtatgaag tggacaagtg
    13261 ggagattgcc gaagaagata aagctaagtt agcaattcca ggttctcgta ttcaagcgac
    13321 cggttattta gaaggtcaac caattcatgc aacccttgtg gtagaagaag gcaatcctgc
    13381 ggcacctgca gtaccaactg taacggttgg tggtgaagct gtcacaggtc ttactagtca
    13441 aaaaccaatg caataccgca ctcttgctta tggagctaag ttgccagaag tcacagcaag
    13501 tgctaaaaat gcagctgtta cagttcttca agcaagcgca gcaaacggca tgcgtgcgag
    13561 catctttatt cagcctaaag atggtggccc tcttcaaacc tatgcaattc aattccttga
    13621 agaagcgcca aaaattgctc acttgagctt gcaagtggaa aaagctgaca gtctcaaaga
    13681 agaccaaact gtcaaattgt cggttcgagc tcactatcaa gatggaacgc aagctgtatt
    13741 accagctgat aaagtaacct tctctacaag tggtgaaggg gaagtcgcaa ttcgtaaagg
    13801 aatgcttgag ttgcataagc caggagcagt cactttgaac gctgaatatg agggagctaa
    13861 aggccaagtt gaactcacta tccaagccaa tactgagaag aagattgcgc aatccatccg
    13921 tcctgtaaat gtagtgacag atttgcatca ggaaccaagt cttccagcaa cagtaacagt
    13981 tgagtatgac aaaggtttcc ctaaaactca taaagtcact tggcaagcta ttccgaaaga
    14041 aaaactagac tcctatcaaa catttgaagt actaggtaaa gttgaaggaa ttgaccttga
    14101 agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt gaagaagtca gtgtgacaac
    14161 tccaatcgca gaagcaccac aattaccaga aagtgttcgg atatatgatt caaatggtca
    14221 cgtttcatca gctaaggttg catgggatgc gattcgtcca gagcaatacg ctaaggaagg
    14281 tgtctttaca gttaatggtc gcttagaagg tactcaatta acaactaaac ttcatgttcg
    14341 cgtatctgct caaactgagc aaggtgcaaa catttctgac caatggaccg gttcagaatt
    14401 gccacttgcc tttgcttcag attcaaatcc aagcgaccca gtttcaaatg ttaatgacaa
    14461 gctcatttcc tacaataacc aaccagccaa tcgttggaca aactggaatc gtagtaatcc
    14521 agaagcttca gtcggtgtcc tattcggaga ttcaggtatt ttgagcaaac gttcagttga
    14581 taacttaagc gttggcttcc atgaagacca tggagttggt gcaccgaagt cttatgtgat
    14641 tgagtattat gttggtaaga ctgtcccaac agctcctaaa aaccctagtt ttgttggtaa
    14701 tgaggaccat gtctttaatg attctgccaa ctggaaacca gttactaatc taaaagcccc
    14761 tgctcaactc aaggctggag aaatgaacca ctttagcttt gataaagttg aaacctatgc
    14821 tgttcgtatt cgcatggtga gagcagacaa caaactagga acgtctatca cagaggtaca
    14881 aatctttgcg aaacaagttg cggcagccaa gcaaggacaa acaagaatcc aagttgacgg
    14941 taaagactta gcaaacttca accctgatct gacagactac taccttgagt ctgtagatgg
    15001 aaaagttccg gcagtcacag caagtgttag caacaatggt ctcgctaccg tcgttccaag
    15061 cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct gaaaatggcg acatcttagg
    15121 agaataccgt ctgcacttca ctaaggataa gaacttactt tctcataaac cagttgctgc
    15181 ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt gaattgccga ctaaggttcc
    15241 agtttacttc acaggtaaag acggctacga aacaaaagat ttgtcagttg aatgggaaga
    15301 agttccagca gaaaatctga caaaagcagg tcaatttacc gttcgaggcc atgtccttgg
    15361 tagtgatctt gttgctgagg tcactgtacg agtgacagac aaactaggcg aagctctttc
    15421 agataaccct aactatgatg aaaacagtaa ccaggccttt gcttcagcaa ccaatgatat
    15481 tgacaaaaac tctcatgacc gcgttgacta tctcaatgac ggagatcatt cagaaaatcg
    15541 tcgttggaca aactggtctc caacaccatc ttctaatcca gaagtatcag cgggtgtgat
    15601 cttccgtgaa aatggtaaga ttgtagaacg gactgttgcg caagccaaac ttcacttctt
    15661 tgcagatagt ggtacggatg caccaactaa actcgtttta gaacgctatg tcggtccaga
    15721 gtttgaagtg ccaacctact attcaaacta ccaagcctac gacgcagacc atccattcaa
    15781 caatccagaa aattgggaag ctgtgcctta tcgtgcggat aaagacatcg cagctggtga
    15841 tgaaatcaac gtaacattta aagctgtcaa agccaaagct atgagatggc gtatggagcg
    15901 taaagcagat aagagcggtg ttgcgatgat tgagatgacc ttccttgcac caagtgaatt
    15961 gcctcaagaa agcacgcaat cgaagattct tgtagatgga aaagaacttg ctgatttcgc
    16021 tgaaaatcgt caagactatc aaattaccta taaaggtcaa cggccaaaag tctcagttga
    16081 agaaaacaat caagtagctt caactgtggt agatagtgga gaagatagcc ttccagtact
    16141 tgttcgcctc gtttcagaaa gtggaaaaca agttaaggaa taccgtatcc agttgactaa
    16201 ggaaaaacca gtttctgaga agacagttgc tgctgtacaa gaagatcttc caaaactcga
    16261 atttgttgaa aaagatttgg cctacaagac agttgagaaa aaagattcaa cactgtatct
    16321 aggtgaaact cgtgtagaac aagaaggaaa aactggtaaa gaacgtatct ttacagcgat
    16381 taatcctgat ggaagtaagg aagaaaaact ccgtgaagtg gtagaagctc cgacagaccg
    16441 catcgtcttg gttggaacca aaccagtagc tcaagaagct aaaaaaccac aagtgtcaga
    16501 aaaagcagat acaaaaccaa ttgattcaag tgaagctagt caaactaata aagcccagtt
    16561 accaaataca ggtagtgcgt caagccaagc agcagtagca gcaggtttag ctcttctagg
    16621 tttgagtgca ggattagtag ttactaaagg taaaaaagaa gactagaaat tttgatacct
    16681 tctttatcat taaagaccaa agaaaaactc ttgtcctaaa tagaagataa agagtctgga
    16741 acaaaatagt tctcaaccac aaaaaagcta gatatttcca attgcggaac tctagctttt
    16801 taattttgag tcgttctctt attgtatagt agattgaaac tagagtagta cacttctact
    16861 tctaaaacat tgttagaaat cgatttgact gtccttatcg atttgtcctg ttcttatttc
    16921 atttcactat gttttaggag gttattggcc ataagtacca atcccatgtc aattctcact
    16981 tgacgcttgc ctctcagatt acatctcttg taacccaaac aagcctttat ctgcccaaag
    17041 acaggttcca catcaatctt gcgttgagcg aaaatctgtc tatcttgggg agataaaagc
    17101 gcctgacatt ctttagcttt caagttttga tagcgttcgt tcatatacag tcccttttga
    17161 ggggctgatt caggttcatc agcgtagtaa accttgattt cctgttgaaa gtctgtctgt
    17221 gttttctggt acttgatatg gtgaaaacga tagcaccagc catcaggatg tatgtagcta
    17281 tcctccttgt cattatagtg ccaattcgct aagtttttag ctgactgttt ataccctctc
    17341 ttttgttcct tatcaaacat ggcatattta atcagaaggg gagtgatttc ttcttgaaaa
    17401 tagacttgta tctgttcttg aagtttggcg gagaatttct ctgtcgtttt cttccacaca
    17461 aaactatact tgtttgcatt ggattcaatc ttagttccgt caataaacaa acaatctaag
    17521 gtcactaact cttccatttt tcaatttttc gaccagagaa aatcccttgt gaataggcaa
    17581 atagaagagt agatacaagc attttagggt gataagacgg gcgaccaaag gcatgatagg
    17641 aggtgtagaa gtgacgttcc tccaaggtat tcaccacttt ttcaatagta aagacgagat
    17701 ggtcttgtgg taagaaggaa ctgatttcta gtggtaaagt tgtttgattt gtgttatagt
    17761 gaatatgcat gggatagcct ttctaaatgg tttattaagc aattctattt taccaagact
    17821 atcgtaacca tgcaaaaaag caacggcaaa tccgttgcct tttttggata taagagacta
    17881 ttgtcccaga ctcttttctt tgtataaaat tgtatagtgt tattgtctat actattttgt
    17941 agagaaagca aaaatcccta gaaaatgctt agggattcga ctatttcatt aagaacaatt
    18001 caacaatcat ctctatatac atgataaggg ttaataaaaa tcctgtacgc cagaagaatt
    18061 tgatgaattt aggatagtaa aagctgcgtt tttttaaaag gaagaaaaag acgagaataa
    18121 tggctaggaa cgagagggct agccccagtc tagggaggaa attatgggta aaggttttag
    18181 ctgtaatcaa gtaatactca aataccaaga ctggaaaagc caaatccgca aagtttcgtc
    18241 ctagtttttt taatctaaaa agtttggtta ggataatgca gacgactaag gtcagtatca
    18301 ataataaaat agatgctaat ttcattaaaa tcatacccat attgtatcat aaaaaaaggc
    18361 taatggaaac gagaaacaga ggaatttata ggaaagtcag gcttttgaga ttgtgggtga
    18421 tttttgttat aatgaaagtt ataaaatctt atgatacctt gaatgattat tatcgaaaac
    18481 tctttggaga aaagactttt aaagtcccta ttgatgcggg atttgactgt cccaatcgtg
    18541 atggaactgt ggctcatgga ggctgtactt tttgtacggt ttccggttct ggagatgcca
    18601 ttgtagcccc agatccgcct atccgtgagc aattttataa ggaaattgac tttattcatc
    18661 gtaagtggcc agatgttcag aagtatctgg tttattttca aaattttacc aacacccatg
    18721 aaaaggtgga agttattcga gagcgttatg aacaggctat caatgagcca ggtgtggtag
    18781 gaatcaatat tggaacgcgc ccagactgtt taccagacga aaccatcgaa tatttggctg
    18841 agttatcgga gtgcatgcat gtgacggttg aattgggctt gcagactact tatgaagcaa
    18901 cctctgacct gattaaccgt gcgcattctt atgaattgta ggtggaaacg gtcaagcgtt
    18961 tgagaaagta tccaaaaatt gagattgttt cccatttgat caatggtttg cctggtgaaa
    19021 cccatgagat gatggttgaa aatgtccgcc gttgtgtcac ggataacgat attcaaggga
    19081 ttaaactgca tttgctccat cttatgacaa atactcgtat gcaacgagat taccatgagg
    19141 gacgtttaca attgatgagt caggacgaat atgtcagggt catctgtgac caactggaaa
    19201 ttattcccaa acatatcgtc atccatcgaa ttacaggaga tgcgcctagg gatatgctga
    19261 ttggtcctat gtggagcctc aataaatggg aagtcctcaa cagcattgag atggagatga
    19321 gacgtcgtgg aagtgttcaa ggatgcaagg ctgtaaaaca ggagtttgaa aatgaaaaga
    19381 ccacttgaga tggcacatga ttttttggct gaggtcgtga caaaagagga tgtcgtagtg
    19441 gatgcgacta tgggaaatgg tcatgacacg ctttttttag ccaagctagc caagcaagtc
    19501 tatgcctttg atattcagaa gcaagccttg gaaaagaccc aagagcgttt gcatcaggct
    19561 ggcttgacaa atgcccagtt aatcttgcaa ggccatgaga cactggacca gtttgtgaca
    19621 aaagctaagg cagggatttt taatttgggc tatttgccgt cagctgataa gtctgtcatc
    19681 acccgaccgc agacaacgat tgaggcatta gaaaagctat gtggcttact tgtcaaaggt
    19741 ggacgaattg ctattatgat ttactatggt catgaaggag gcgacctcga gagagatgct
    19801 gtcttggatt ttgtgatcca gttgaaccaa caagagtaca cagctgccat ttaccgaact
    19861 ttaaaccaag tcaacaaccc gccgttttta gtgatgattg aaaaattaga gagatacaga
    19921 catggataaa caatacctac acgaaaagct ggatgccatg cgccagaatt ttgttgaatc
    19981 aacctaccac gaacgagcgg tgggcgtgct agaccaagcg catatgagca aaaaaatgct
    20041 taaaatcaag aaaaaattag ttgctcttga aatggaacgg tgccagagaa aaattgagca
    20101 caaagactgt tccaagattg accaaaaaat caaagagcag aaggagatat ttgaatcctg
    20161 ttgtaaaaaa gattaaggag gacgtgcgtg gaattactga tttacctcat cctattttta
    20221 ctggtcttga ttgtctcaag tacaaccaat aagctcctac cctttttgcc tctccctttg
    20281 gtgcagattc ttttgggaat tgtgattggt ctctttttac ccaatactga ctttcacctt
    20341 aatacggagt tgtttttggc actggttatc ggccccttgc ttttccgaga ggctgaagaa
    20401 gcagatgtta cggctatttt aaaacactgg cgaatcattg tttatctcat atttccagtg
    20461 atttttatct cgaccctgag tttgggtggc ttggcccatc ttctttggtt cagccttccc
    20521 ttggcagctt gcttggctgt tggggcagcc cttggtccta cggacttggt ggcctttgcc
    20581 tctctttcgg agcgttttag ctttcctaag cgcgtgtcca atattcttaa gggcgaagga
    20641 ctcttgaatg atgcttctgg tttggtggct tttcaggtag ctttgacagc ttggacaact
    20701 ggagcttttt ctctggggca agctagcagt tcactcatct tttcaatcct aggcggtttt
    20761 ttaattggat ttttaacagc catgaccaac cgcttcctcc ataccttctt gctaagtgtg
    20821 cgtgcaacgg atattgccag tgaactttta ttagaattga gtttgcctct tgtgaccttc
    20881 tttctggcag aagaagttca tgtttcaggt attattgccg tcgtagttgc tggaatttta
    20941 aaggcaagtc gtttcaagaa aatcacgctc ctcgaagccc aagtggatac ggtgaccgag
    21001 acggtctggc atacagtgac ctttatgctc aacggttctg tctttgtgat tttagggatg
    21061 gagctggaaa tgatagcaga acctatcttg accaatccaa tctataatcc tctactttta
    21121 ttgctatctc tcatcgccct tacctttgtc ctctttgtca ttcgttttat tatgatctat
    21181 ggctattatg cctatagaac ccgacgccta aagaaaaagc taaataagta tatgaaggac
    21241 atgtttctct tgaccttttc aggtgttaag ggaacggtgt cgattgctac gattctcttg
    21301 ataccaagta atctagaaca ggagtatcct ctcttgcttt tccttgttgc aggtgtgacg
    21361 cttgtcagct ttttaacagg tctcttggtc ttgcctcatc tttctgatga agaggaagaa
    21421 agcaaggatt atctcatgca tatcgccatt ttgaatgaag taacgctaga gttggaaaaa
    21481 gagttggaag acaccagaaa taaacttccc ctctatgcgg ctattgacaa ttatcatgga
    21541 cgtattgaaa atctcatttt aagccaagaa aaccaggatg atcaagaaga ctgggctgct
    21601 ttgaaactct taattcttag tattgaaagt gatggtttgg aacaggccta tgaagagggg
    21661 aacattagca atcgtgctta ccgagtttac caacgttatc tgaaaaatat agaacaagga
    21721 atcaatcgta aacttgcctc aagactgacc tattattttc ttgtttcctt gaggatttta
    21781 cgttttcttc ttcatgaagt ttttactctt ggaaagacct tccgtagctg gaaggacaag
    21841 gagcaaagcc gtctccgtgc tcttgattat gaccaaattg cagagctcta tcttgccaat
    21901 acagagatga ttattgaaag tttggaaaac ctgaagggag tctacagacg ctctttgatt
    21961 agttttatgc aggagtctcg tcttcgagaa acagctatta tcagcagtgg tgcctttgtc
    22021 gaacgggtta tcaatcgtgt caaacccaac aatatcgatg aaatgctgag aggctattat
    22081 ctggagcgca agttgatttt cgaatacgaa gaaaaacgat tgattacgac taagtatgcc
    22141 aagaaattac gacaaaatgt aaataactta gagaactatt ccttgaagga agctgccaat
    22201 accctgccgt atgatatggt ggaattggta agaagaaatt agttaatact cttcgaaaat
    22261 ctcttcaaac cacgtcagcg tcgccttgga ttatatatgt gactgacttc gtcagtttca
    22321 tctacaacct caaagcaggg ctttgagcaa cctgcggcta gcttcctagt ttgctctttg
    22381 attttcattg agtataagat tgtaagtgaa ggagtgtgac atgaaaaaat ggtggaaaga
    22441 gctgatagac aagcctttat taaaagcttt tttgcattat tatcaagcat cagatagtga
    22501 gttgaccagt gtcgcagtag cctactattg gttgatttcg attttccccc tgcttttggt
    22561 ggtggtcaat atcctccctt attttcagat tcctgtggga gaatttctgg gctttatgaa
    22621 agacgtcctg cccccaagcc tctatgaagg tgtggaaaaa atagccagag aagtcttgac
    22681 gcaaccttca acaggtttat tgagtttttc tgttttatcg gcgttatgga gtttttcaaa
    22741 atctatgaat ttcttgcaaa aagcttttaa caaggcttat ggcgtcgaaa agagtcgtgg
    22801 acttatttcc catcagatgc tgagtctcct agtcagtttt ggcttgcagc tcctctttgc
    22861 gtttgccttg tttttgatct tatttggtca gatgattttg gctttacttg ctcattattg
    22921 gacaaaagat ggcattatct atcaggcttt acaagggttg gcaggtcctc tgatttacgc
    22981 cctcctcttt gctatcttgg tcatgcttta ttattttctt cccaatctat ctaacaggaa
    23041 aattagctat accctaccag gcagtgcctt tgttctctta gtgattttag gtttactaac
    23101 tctgttctct agttatctca attactatgt ccatcatttg gtggatgtcc gaattttagg
    23161 ttccgttctt cttgttgtta tgatgttttg gtttatcttg attgctaaaa ttgttatcct
    23221 aggcgcggtt atcaatgcca gtatgcagag tttgaaagat ccggtcttta aaaaagacta
    23281 actatttatc cattataaaa gcgcatagta tcaagacttt atagaacctt gatactatgc
    23341 gcttttgcgc ttttgtgctt tgacagtttt ttgtatagtt tttgtccaag atttctaaat
    23401 catctgatta aattcctatt ttcccctatc attgtccctg ttttttcgaa aatggaagga
    23461 gtataataaa tctatcaata aaatgatagg aggaacttta tgggtcatat tttctttttt
    23521 ctaagtgtct ttttggcagg gattctatcc ttcttttctc cttgtatctt acctttgtta
    23581 ccggtctata caggagtgtt actagatgat aaggatggtg ctcaggcttc tagcggcaaa
    23641 ttttcaatct cagttactag tttattacga actctggcct ttatagcagg aatttccttt
    23701 atatttattt tgttgggcta tggagctggt tttttaggcg atttgcttta tgcttcttgg
    23761 ttccaatatc ttactggggc aattattatc cttcttggtt tgcaccaaat ggagattcta
    23821 cactttaagg ggctttataa ggaaaagagg ctacaactgc aaggacaggg gcaaaatggt
    23881 aagggctata gtcaggcatt tttattgggc ttgaccttta gttttgcttg gacgccttgc
    23941 gtggggccgg ttctggggtc tgttttggcc ttggcggctt caggtggttc aggagcttgg
    24001 cagggagctg gtctcatgtt ggtgtatacg ctgggcttgg cgctaccatt cttgcttcta
    24061 gctctgacct ctagttatgt tttgaaacat ttccggaaac ttcatcccta tctcggaatc
    24121 ctcaaaaaag tgggtggttt tctcattatt gtgatgggac tcttggttct gtttggaaat
    24181 gcttcaattt taagtcaatt atttgaataa aatggaaagg aatatcaata tgaaaaaatg
    24241 gcaaacatgt gttcttggag caggttcgct cctttgtttg acggcttgtt caggcaagtc
    24301 cgtgactagt gaacaccaaa cgaaagatga aatgaagacg gagcagacag ctagtaaaac
    24361 aagcgcagct aaagggaaag aggtggctga ttttgaattg atgggagtag atggcaagac
    24421 ctaccgttta tctgattaca agggcaagaa agtctatctc aaattctggg cttcttggtg
    24481 ttccatctgt ctggctagtc ttccagatac ggatgagatt gctaaagaag ctggtgatga
    24541 ctatgtggta ttgacagtag tgtcaccagg acataaggga gagcaatctg aagcggactt
    24601 taagaattgg tataagggat tggattataa aaatctccca gtcctagttg acccatcagg
    24661 caaacttttg gaaacttatg gtgtccgttc ttacccaacc caagccttta tagacaaaga
    24721 aggcaagctg gtcaaaacac atccaggatt catggaaaaa gatgcaattt tgcaaacttt
    24781 gaaggaatta gcttaggagg tgtcttatga atgataagtt aaaaatcttc ttgttgctag
    24841 gagtattttt tctatccata accggtttct atgttctatt gatacgaaat gcagggcaga
    24901 cagatgcctc gcaaattgaa aaggcggcag ttagccaagg aggaaaaaca gtgaaaaaaa
    24961 cagaaattag taaagacgca gacttgcacg aaatttatct agctggaggt tgtttctggg
    25021 gagtggagga atatttctca cgcgttcccg gggtgacgga tgccgtttca ggctatgcaa
    25081 atggtagagg agaaacaacc aagtacgaat tgattaacca aacaggtcat gcagaaaccg
    25141 tccatgtcac ctatgatgcc aagcaaattt ctctcaagga aatcctgctt cactatttcc
    25201 gcattatcaa tccaaccagc aaaaataaac aaggaaatga tgtggggacc cagtaccgta
    25261 ctggtgttta ttacacagat gacaaggatt tggaagtgat taaccaagtc tttgatgagg
    25321 tggctaagaa atacgatcaa cctctagcag ttgaaaagga aaacttgaag aattttgtgg
    25381 tggctgagga ttaccatcaa gactatctca agaaaaatcc aaatggctac tgccatatca
    25441 atgttaatca ggcggcctat cctgtcattg atgccagcaa atatccaaaa ccaagtgatg
    25501 aggaattgaa aaagaccctg tcacctgagg agtatgcagt tacccaggaa aatcaaacag
    25561 aacgagcttt ctcaaaccgt tactgggata aatttgaatc cggtatctat gtggatatag
    25621 caactgggga acctctcttt tcatcaaaag acaaatttga gtctggttgt ggctggccta
    25681 gttttaccca acccatcagt ccagatgttg tcacctacaa ggaagataag tcctacaata
    25741 tgacgcgtat ggaagtgcgg agccgagtag gagattctca ccttgggcat gtctttacgg
    25801 atggtccaca ggacaagggc ggcttacgtt actgtatcaa tagcctctct atccgcttta
    25861 ttcccaaaga ccaaatggaa gaaaaaggct acgcttattt actagattat gttgattaat
    25921 actcttcgaa aatctcttca aaccacgtca gcgtcgcctt accgtatgta gggttactga
    25981 ctccgtcagt tttatctaca acctcaaagc tatactttga gctgacttcg tcagttttat
    26041 ctacaacctc aaagcggtac tttgagaaac ctgtggctat cttcctagtt tactttttga
    26101 tttttattga gtataagagg tctttcctaa gcagttagag gagaattttg ctatactgat
    26161 actagtaagt ggtaaaggag cagagcatga cctacacaat cttaatcgta gaagatgaat
    26221 atctggtaag acaaggtttg actaaactgg tcaatgtagc agcctacgat atggaaatca
    26281 tcggtcaggc tgaaaatgga aggcaggctt gggaattgat ccaaaagcag gttccagata
    26341 tcattttaac cgatatcaac atgcctcatc taaatggcat ccagttggcc agtctggtac
    26401 gagaaaccta tcctcaggtt catttggtct ttttaacagg ttacgatgat tttgattatg
    26461 ccttgtctgc tgtcaaacta ggtgtggacg actacctgct caaacccttt tctcgtcagg
    26521 atattgagga aatgttgggg aaaatcaaac aaaaactaga caaggaagag aaagaagagc
    26581 agttacaaga tttattgact aataggtttg aaggaaacat ggcccagaaa atccagtctc
    26641 atctggctga tagccaattt agtttaaagt ctttagccag tgacttaggt tttagtccga
    26701 cctatctgag ttccttgatt aagaaagagt tgggcttgcc ttttcaggat tatctagtga
    26761 gagaacgtgt taaacaagcc aagctcttgc ttttaactac agatctgaag atttatgaga
    26821 tcgcagagaa ggttggtttt gaagatatga actattttac ccaacgtttt aagcagattg
    26881 caggtgtgac acctcgtcag tttaagaagg gagaagaccg atgaagcgtt cttctctttt
    26941 agttagaatg gttatttcca tctttctggt ctttctcatt ctcctagctc tggttggaac
    27001 tttctactat caatcaagtt cttcagccat tgaggccacc attgagggca acagccaaac
    27061 gaccatcagc cagactagcc actttattca gtcttatatc aaaaaactag aaaccacttc
    27121 gaccggtttg acccagcaga cggatgttct ggcctatgct gagaatccca gtcaagacaa
    27181 ggtcgaggga atccgagatt tgtttttgac catcttgaag tcagataagg acttgaaaac
    27241 tgttgtgctg gtgaccaaat ctggtcaggt catttctaca gatgacagtg tgcagatgaa
    27301 aacttcctct gatatgatgg ctgaggattg gtaccaaaag gccattcatc agggagctat
    27361 gcctgttttg actccagctc gtaaatcaga tagtcagtgg gtcatttctg tcactcaaga
    27421 acttgttgat gcaaagggag ccaatcttgg tgtgcttcgt ttggatattt cttatgaaac
    27481 tctggaagcc tatctcaatc aactccagtt ggggcagcag ggctttgcct tcattatcaa
    27541 tgaaaaccat gaatttgtct accatcctca acacacagtt tatagttcgt ctagcaaaat
    27601 ggaggctatg aaaccctaca tcgagacagg tcagggttat actcctggtc acaaatccta
    27661 cgtcagtcaa gagaagattg caggaactga ttggacggta cttggcgtgt catcattgga
    27721 aaagttagac caggttcgga gtcagctctt gtggaccttg cttggggcca gtgtcacatc
    27781 tcttcttgtc tgtctctgct tagtgtggtt cagtcttaaa cgctggattg ctcctttgaa
    27841 ggatttgaga gaaaccatgt tggaaattgc ttctggtgct caaaatcttc gtgccaagga
    27901 agttggtgcc tatgaactga gagaagtaac tcgccaattt aatgccatgt tggatcagat
    27961 tgatcagttg atggtagcta ttcgtagcca ggaagaaacg acccgtcagt accaacttca
    28021 agccctttcg agccagatta atccacattt cctctataac actttggaca ccatcatctg
    28081 gatggctgaa tttcatgata gtcagcgagt ggtgcaggtg accaagtcct tggcaaccta
    28141 tttccgcttg gcactcaatc aaggcaaaga cttgatttgt ctctctgacg aaatcaatca
    28201 tgtccgccag tatctcttta tccagaaaca acgctatgga gataagctgg aatacgaaat
    28261 taatgaaaat gttgcctttg ataatttagt cttacccaag ctggtcctac aaccccttgt
    28321 agaaaatgct ctttaccatg gcattaagga aaaggaaggt cagggccata ttaaactttc
    28381 tgtccagaaa caggattcgg gattggtcat ccgtattgag gatgatggcg ttggcttcca
    28441 agatgctggt gatagtagtc aaagtcaact caaacgtggg ggagttggtc ttcaaaatgt
    28501 cgatcaacgg ctcaaacttc attttggagc caattaccag atgaagattg attctagacc
    28561 ccaaaaaggg acgaaagttg aaatatatat aaatagagta gaaactagct aactcccagt
    28621 taattctggg agttttatgc gtaattgggc aaactttata ggttgtctat cttgctaaaa
    28681 acaagaaaaa acggtatgat agaagagtga caacagaggt aacagagatg aacgagacac
    28741 agattcaaag agaaacacgt caggtagtgg aagatgtttt agaaaagacc aatttgaagc
    28801 agggggtcct ttttgtttta ggtctatctt ctagtgaggt gctaggtggt cagattggga
    28861 aagaatccag tcaagagatt ggtgagctga tagtggagac tatcttgggt attctaggta
    28921 gtagaggtat ccatttagca gttcaaggtt gtgagcatgt caatcgggct ctcgttgttg
    28981 aacgtcaggt ggcagagcag tttgatctgg aaattgtcag tgtccatcct actcttcatg
    29041 caggaggttc ggggcagttg gcagccttta agtttatgca ggatccagtt gaggttgaat
    29101 ttatcaaggc tcatgctgga ttggatatcg gagacactgc aattggcatg catgtcaagc
    29161 atgttcaggt tccgattcgc cctattttga gagagattgg tcatgcccat gtaacggcac
    29221 tggctagtcg tccaaaatta atcggaggtg cgcgtgcgca ctatccgcaa gacgctatta
    29281 gaaagtcttg agaatgaata aaggagataa aagtgtttaa aaaagaccgt ttttcaattc
    29341 gtaagattaa gggagttgta ggctctgtat ttcttggaag ccttttgatg gctccttctg
    29401 tagtggacgc agccacctat cactatgtaa ataaagagat tatttcacaa gaagctaaag
    29461 atttaattca gacaggaaag cctgacagga atgaagttgt atatggtttg gtgtatcaaa
    29521 aagatcagtt gcctcaaaca gggacagaag catctgtttt gacagctttt ggtttgctga
    29581 ctgttgggag cttgctttta atctacaaga gaaagaaaat tgctagcgtc tttctagttg
    29641 gagctatggg attggtagtt cttcctagtg caggggctgt agacccagtt gcgaccctag
    29701 cgctggctag tcgagagggt gttgttgaaa tggatggcta tcgctatgtt ggttatctat
    29761 caggtgacat cctcaaaacg cttggcttgg acactgtttt agaagaaacc tcagcaaaac
    29821 ctggagaggt gactgtagtc gaagttgaga ctcctcaatc aacaacaaat caggagcaag
    29881 ctaggacaga aaaccaagta gtagagacag aggaagctcc aaaagaagaa gcacctaaaa
    29941 cagaagaaag tccaaaggaa gaaccaaaat cggaggtaaa acctactgac gacacccttc
    30001 ctaaagtaga agaggggaaa gaagattcag cagaaccatc tccagttgaa gaagtaggtg
    30061 gagaagttga gtcaaaacca gaggaaaaag tagcagttaa gccagaaagt caaccatcag
    30121 acaaaccagc tgaggaatca aaagttgaac caccagtaga acaagcaaaa gtcccagaac
    30181 aacccgtgca acctacacaa gctgagcaac caagtacacc aaaagaatca tcacaacaag
    30241 aaaatcctaa agaagatagg ggagcggaag agacaccgaa acaagaagat gaacagccag
    30301 cagaagcccc agaaatcaag gttgaagaac cagtagaatc aaaagaggag actgttaatc
    30361 aacctgttga acaaccaaaa gtggaaacgc ctgctgtaga aaaacaaacg gaaccaacag
    30421 aggaaccaaa agttgaagta acaagtattc cccaaactac tcgctatgag gaagacctta
    30481 ctaaggaaca cggaacgcgt gaagttgtta aggaaggtaa gaatggcagt agaacagtta
    30541 ctactccata tatcttgaat gcgacagatg gtacgactac agaaggcact tcgacaactg
    30601 atgaagctga gatggagaaa gaggttgttc gtgttggcac gaaacccaaa gaaaaattag
    30661 ctccagtctt aagtttgaca agtgttacag ataatgcaat gttgcgtagt gcgagactta
    30721 cttatcattt ggaaaataca gatagtgttg atgtgaaaaa aattcatgct gaaattaaaa
    30781 atggcgataa ggttgtcaaa actattgact tatctaaaga gagattatca gatgctgttg
    30841 acggtcttga actttataaa gattataaga ttgtgacgag tatgacctat gatagaggta
    30901 atggtgaaga aacctctacg ttggaagaaa ctccactacg attagacctc aagaaggttg
    30961 aattgaaaaa catcggctct actaatctcg tcaaagtaaa tgaggatggt actgaggtgg
    31021 caagtgactt cttaacaagt aaacctgtgg atgtgcagaa ttactacctc aaagtaactt
    31081 cacgtgataa taaagtgttt cgcctcacag ttgaaaaaat tgaagaggtg actgaggaag
    31141 gtcaaccact ttacaaagtc actgctaagg ctcctaattt gattcagcac acggatgcga
    31201 ctaaaatgca agacgaatac gtgtattata ttgaaaaaac acgtgcaaca gatggtgata
    31261 tttactacaa ctttaacgac ttagtaaacg ccatgaacaa aaacaaaact ggtacattca
    31321 aacttggtgc tgatttgaac gctacaggtg taccgacacc tgctaagtcg tatgttacag
    31381 gtgatttccg aggtactttg acaagtgttg atggtgaaca ttacacaatt cataatacaa
    31441 gtcgcccatt gtttaataat attataggtg ggactatcaa agatattaac cttggcaatg
    31501 ttaatattca catgccatgg gcaaataacg ttgcatcgtt agctaatatt attaaaggtg
    31561 gaaccactat tgaaaatgtc aaagttacag gtaatgttct tggtaaagac tgggtatctg
    31621 gatttataga taaaatagat agtggcggta cattgagaaa tgtagctttt attgggaatg
    31681 tgacctctgt tggtacaggt ggttcgttct tgactggtat tgttggtgaa aactggaagg
    31741 gactggtaga acaggcttat gtagatgcca atattcgagg gaagaaagct aaggctgcag
    31801 gtatagctta ctggtcgcaa aatggaggcg ataactatgc tgtaggtaga tatggagcaa
    31861 ttaagaaatc tgtcgttaaa ggttcaatag atgtagaaaa accaattgaa gttggtggcg
    31921 ctgttggaag tttaaattat cttggttata tagaagacac tgttgctatg atgaaagtta
    31981 agaacggtga aattttctac ggttcgcatg atatcgatac cgatccatat tacacaggag
    32041 aacgagtaaa tagaaatttc attgttgacg gtgtaagtga aggtaaatct tcgtataaat
    32101 actctaaaca acaaaatcgc attaaatcag tatctcaaga ggaagctgat aagaaaatta
    32161 aagaattggc tatcacagca gataaatatg caattacaga gccaattgta aataaactca
    32221 acgctctcac aacacgtgat aatgagtata gaacaacaca agattacaaa gcagaccgtg
    32281 aacttgctta tcgtaatatc gaaaaacttc aaccattcta caataaagag tggattgtag
    32341 accaaggtaa taaagttcca tcaaattcta aattattaac tacagaagta ttatctgtta
    32401 caggtatgaa agatggtcaa tttgtgactg acttatcaga aattgataaa attatgattc
    32461 actatgcgga tggcaccaaa gaagaaatga acgtgacagc ggttgctgat tctaaggtga
    32521 aacaagttcg tgagtatgac gtgactgatt tgggtgttgt ttacactccg aatatggttg
    32581 ataaaaaccg cgaccaattg attgcagatg tgaaagcgaa attgtcgtca gttgaattga
    32641 tttcccctga agttcgtgct cttatggata aacgtggtaa agctgaagaa aatacggaag
    32701 gtcgtcaaaa tggatacatt agagatctat tccttgaaga aagctttgct gaagtgaaag
    32761 ctggtttggg taaattggtt aaagctttgg ttgaaaacga agattatcaa ttaaatagcg
    32821 atgaagcagc aatgcgcgcg ttaattaaga aagttgaaga caataaagct aaaatcatga
    32881 tgggactgac ctacttaaat caatattata gttttaaata cgctgagtta tcaattaaag
    32941 atattatgat gtttaaacct gatttttatg gtaagaatgt taatgtctta gatttcttaa
    33001 tcaaaattgg ttcaagtgaa agaaatgtta aaggtgatag aactttagaa gcttatcgtg
    33061 aaactatcgg tggaacaatt ggaataaatg aattaaatgg attcttacat tacaatatga
    33121 agctatttac taaccatata gatataaatg actggtttaa gaaagctatt gaaaagaatg
    33181 cttatgtagt tgaacaacca tcaacgaacc ctgcatttgc caacaaaaaa tatcgtctat
    33241 acgaaggaat taataatggg caacatgggc ggatgatttt acctcttctt aacttgaaaa
    33301 atgcacatct atttatgatt tcaacataca acactatctc gtttagttcg tttgaaaaat
    33361 atggcaaaga cacagatgaa aaacgtgaaa agtttaagag tgagatcaat aaacgtgcta
    33421 aagagcaggt taattactta gatttttggt cacgtcttgc tactgataat gtccgtgata
    33481 aacttcttaa gagtcaaaat gtagttccaa ctcctgtatg ggataatcat aatagcccga
    33541 acggatgggc tagtagacat ggtcatatag atgggaaacc ggattatgct ccaattcgtg
    33601 agttctttgg gcgaatcaat aagtatcatg gttacaaata tggatatggc gcatatgcat
    33661 atatttttgc agcacctcaa ccgatggatg cagtttattt cgttatgaca gatttaatta
    33721 gtgactttgg aacatctgca tttacacatg aaactactca cattaatgat cgtatggctt
    33781 actatggtgg tcattggcat cgtgaaggta cggatcttga agcatttgct caggggatgt
    33841 tacaaacgcc atcggtatca aatccaaacg gagaatatgg cgcattaggt ctaaatatgg
    33901 cgtatgaacg tcaaaatgat ggaaatcaat ggtataatcc aaatcctaac aaacttaaat
    33961 ctcgcgctga aattgatcac tacatgaaga actacaatga agctcttatg atgttagatt
    34021 atctggaagc agaatctgtt ttacctaaat taaaaggtaa caatgataga tggttcaaga
    34081 aaatggataa acaaatgcgt aaggacggac aacctcacca gtttgacaaa attcgcgatt
    34141 taaataatga agagaagaaa attcaattag cttctattga ggatttagtt gataataact
    34201 ttatgactaa acacggtgct cctggaaatg gtacatataa cccatcagat tttagttcag
    34261 catatgttaa tatgaatatg atgactggtg tatacggagg taactcaagt gatggggctc
    34321 ctggcgctgc ttcatttaaa cataatactt tccgtatgtg gggatacttc ggatacgaaa
    34381 atggattcat cggatatgcc tctaataaat ataaagccga agccaataaa gcaggtcaaa
    34441 ctctaagtga taaatatatc atcaataaag tttctggtgg tacatttaat acacttgaag
    34501 cgtggaagaa agaatggttt aaacaaatca aaactaaagc tcaaaaagga ttcacagcaa
    34561 ttgaaattga tggtaaaact attgattcat atgaaaaatt aaaagactta tttgataaag
    34621 ctgttgaaga agatcttaaa ggaactggaa cggataagac tgtgaaactt aaagaaaaag
    34681 tatacaaaca actccttaaa aacacagacg gtttctctgg tgatctattt actgcaccac
    34741 aagcatagaa tgaataaaat cggaaaaagg tagatcagct ttgtctgtat ctgccttttt
    34801 atgctatact taaggtatgc atagaaaaac agtgattgat tttaggactt taggggagag
    34861 atataccttt acccagccta ttaaagagtt gaaaacgaga aatgtagcag aagtggcaga
    34921 tttgctggca caagtggaaa gctaccaaga gcaagattat tatgtggtgg ggtatgtcag
    34981 ctacgaggct gcacctgctt ttgaggagaa attagcagtt cacaaggttc ctctactggg
    35041 cgagtacttg ctttacttta ctgttcacga tagggtggag acctccccta ttcctctgac
    35101 ttatgaggat attgatttgc cctcaaattg gcaggaagta acgtctgcag agaactatga
    35161 aaaggccatt gcccagatac accatcactt gaggcaggga gacacctatc aggtcaacta
    35221 caccgtccaa ctcaagcaaa agttaagtgc caatcctttt gccatctaca atcgtatggt
    35281 ggtagagcag gaggcgggct acaatgccta tgtggaacat gacgagatgg cagtgatttc
    35341 catgagccca gagctctttt ttgagcaaaa tgatcgcgag ttgacaacac gaccaatgaa
    35401 ggggacgact cagcgtgggg taactgacca agaagatctt gaacaggcca gttggttggg
    35461 acaggatccc aaaaatcgct ctgaaaatat gatgattgtg gacctcttgc gcaatgatat
    35521 gaaccgtatt tctgaagttg ggagcgagca cgtggagcgt ctgtgtcagg tagagcagta
    35581 ttcaactgtt tggcagatga cttcgaccat caagagtcag ttgcgagagg atgtggacct
    35641 tgttgaaatc ttccgctcac tctttccttg tggttccata acgggtgcac cgaaaattgc
    35701 gacaatggag attatcaagg acttggagcc tcaaccgcgt ggagtctact gtggaacgat
    35761 tggtctcttg cttccaaatg gacgacggat ttttaatgtg gccattcgta ccattcaact
    35821 tcacaaaggt caagcaattt atggagttgg cggagggatt acttgggata gcacatggga
    35881 atctgaatac cgagaggttc atcaaaaggc agcagttctt tatcgtaaac aagctcgctt
    35941 ccaactgatt acgacagggg aaatcagcca gaagaacctg ctgtttgaag atcaacatct
    36001 ggaaagactg agaaaagcca gtcgttattt tgcctttcct tttgatgcag aagacttggg
    36061 acacaagatt gaggaagagt gtcaggattg tgaagctaat caagattacc gcttgcgaat
    36121 cagccttagc aaatctggag agatagaagt caatcgtcaa gtattaaccc ctctcagtac
    36181 aagcttttgt caggcccaag tctgtcttca ggaagctgct ttgaatcaat cctttaccta
    36241 ctttaaaacc actcaccgac cgcatttgag cctaggagaa caagagaaga tttaccacaa
    36301 taagtcagga gaactgcttg aaacctctat aggaaatttg gttctgaaaa tcgctggaaa
    36361 actctacaca ccgcctatcc gacttggaat cttgccagga atttaccgtc agcatttgct
    36421 agaaacagga caggtagaag agaaagtctt gaccttggca gatttaaccc aagcagaagc
    36481 tatttacggc tgtaatgcag tgagaggctt gtatgaacta agccttgagg agaactagat
    36541 gaaattgata tttttgcatg ggttagggca gtcagcagag tcttggaaag aagttcggaa
    36601 tctactgaca gattatcctt ctgaggctat cgagttattt ccttctggag ttagtaacta
    36661 tcaacaagct aaagagcgag tttatcagca cctagctcaa gagacagaac cttttgtttt
    36721 gattggattg tccttaggtg ctaccctgac actagaactt tccagttacg atttaccaaa
    36781 tcttcgagct ttgattctgt caggatgccc gcttaaatta gcagggaata tcctatttta
    36841 tcttcaattg ctgattttta aactacttcc caaaagagta tttgaaaaac agggagcaga
    36901 caagactctt atggtcggag tttctgagga attgaagaca cttgatttaa cggatatagc
    36961 agggacttgc tcctatccaa ccttactaat ttgtggcagc aaagataaac cgaatcttag
    37021 ttctatgaaa gctctccata gactgttaac agattcgcag tttcagatca ttcctgatgg
    37081 ccctcatgtc ttgaataagg caaaaccaaa ggagtttgta gaaaagacca gaagtttcct
    37141 tgaattgctg aaataagttt gataaaataa tattgaaatc gatatcataa ttatgggaga
    37201 aagaaatgaa taaacgtcta tttttaaaaa tgagtctggt gacgttgcca attttagcct
    37261 tgttttcaca accagttttg gcggaagaaa acatccattt ttcgagctgt aaggaagctt
    37321 gggcgaatgg ctattcggat atttacgagg gagaacctgg ttattctgcc aagttagacc
    37381 gtgatcatga tggtgtggct tgcgaattga aaaatgctcc taagggtgct tttaaagcaa
    37441 aacagtcaac ggctattcaa atcaacacaa gttcagcaac aacaagtggt tgggttaagc
    37501 aggacggcgc ttggtactac tttgatggaa atggaaatct agtgaaaaat gcatggcagg
    37561 gaagctatta cctgaaagct gatggtaaaa tggcacagag tgaatggatt tatgactctt
    37621 cttatcaagc ttggtattat ttgaaatcag atggttctta tgcaaaaaat gcatggcaag
    37681 gagcttatta ccttaaatca aacggtaaaa tggtacaagg tgagtgggtt tatgattctt
    37741 cttaccaagc atggtattac ttgaaatcag atggttcata tgctcgcaat gcatggcaag
    37801 gaaactacta tttgaaatca gatggtaaaa tggctgtcaa tgaatgggtt tatgatgcca
    37861 cctatcaagc atggtattat ttgacatcag atggttctta tgcttacagt acatggcaag
    37921 gaaattacta tctaaaatcg gatggtaaaa tggctgtcaa tgaatgggtt gatggtggac
    37981 gttattatgt tggcgctgac ggagtttgga aggaaggtca agcaagtaca gcttcttcta
    38041 gtaatgatag caatagtgaa tattctgctg ctttaggaaa ggcaaaaagt tataattcgt
    38101 tattccacat gtcaaaaaaa cgtatgtata gacaattaac ttctgatttt gataaatttt
    38161 caaatgatgc agctcaatat gccattgatc attagatgat taacagatac tggtaggcga
    38221 aaaaattcct tataattcat ttacgcaaac ctttgcataa gtgaatggat tttgatatac
    38281 tagtactgta agcattttca attactacac aatgaaaaag gagaatatga tgagtcaaaa
    38341 gattattggg attgaccttg gtggaacttc tatcaaattt gcaatcttaa caacagcagg
    38401 agaaatccaa ggaaaatggt caatcaagac caacattttg gatgagggaa gtcatatcgt
    38461 tgatgatatg attgagtcta ttcaacatcg tttggacttg cttggattgg cagcagcgga
    38521 cttccaaggc attggaatgg gatcaccagg tgtggttgac cgtgacaaag ggactgttat
    38581 cggtgcctac aacttgaact ggaaaaccct tcaaccaatc aaacaaaaga ttgaaaaagc
    38641 tttgggcatt ccatttttca tcgataatga tgccaacgta gcagctcttg gtgagcgctg
    38701 gatgggtgct ggagataacc aaccagacgt tgtctttatg acactcggta ctggtgttgg
    38761 tggcggtatc gtcgcagaag gcaaattgct tcacggtgtt gctggtgcag caggtgagct
    38821 tggtcacatc actgttgact ttgaccagcc aatctcatgt acttgcggta agaaaggctg
    38881 ccttgagaca gttgcttcag caacagggat tgtcaacttg actcgtcgct atgccgatga
    38941 atacgaaggc gatgcagcct tgaaacgctt gattgataat ggagaagaag taactgctaa
    39001 gactgtcttt gatctcgcaa aagaaggaga cgaccttgct ttgattgttt accgtaactt
    39061 ctcacgttac ttgggaatcg cttgtgctaa cattggttca atcctaaacc catcaacaat
    39121 cgtcatcggt ggtggtgtgt cagctgcggg agaattcctt ctacaaggtg ttcaaaaagt
    39181 ttacgatgaa aatagtttcc cacaagtacg cacatctact aaattagctc ttgcaactct
    39241 aggaaatgac gctggagtta tcggagcagc atcacttgta ttgcaataag ataatgagag
    39301 aggaaaatgc taacctagag ttagtaatgt tcctctttta ttttttatgc tatactagtt
    39361 aggacaatga atgaggtgag agtaaatgac aaaagcagat acgattttta aagagaatat
    39421 tgaatgcatt ctaaaggaag gtgttttctc agagcaagct cgtcctaagt acaaggatgg
    39481 gactgttgct aattccaagt atgtaactgg tgccttttcc gagtacgact tatctaaagg
    39541 agaatttcct atcacaacct tgcgtcccat tgcaatcaaa tccgccatca aagaagttct
    39601 ctggatttat caagaccagt caaatagctt agaagtgctt aatgacaagt acaatgttca
    39661 ctactggaat gactgggaag ttggagacac gggaaccatt ggtgagcgct atggtgccgt
    39721 tgttaagaaa cacgacatta tcaataagct tctcaaacag ttggaaacca atccttggaa
    39781 tcgccgcaat attatttcgc tctgggatta ccaagctttc gaagaaacag atgggctgct
    39841 cccgtgcgcc tttcagacca tgtttgatgt ccggcgtgtt gatggggaaa tctatctgga
    39901 tgcgaccttg acccagcgct ccaatgatat gctggtggcc caccacatca acgctatgca
    39961 gtatgtggct ttgcagatga tgattgccaa acattttggc tggaaggttg ggaagttctt
    40021 ctatttcatc aacaacctcc atatctatga taatcaattt gaacaagctc aggaattgct
    40081 ccgtcgggag ccgtcaaact gccaaccacg cttggtttta aatgttcctg atgggactaa
    40141 tttctttgat atcaaagcag aagattttga gttggtggat tatgaccctg ttaagccaca
    40201 gttgaagttt gacctagcta tttaaaagaa tagaaaaaag aagttgagaa taatcccaac
    40261 ttcttttgtt tcttaacgtg atacgcggcg acgagctgct tttttacgat tttcttcgat
    40321 gaaagctgct ttttgctctt ctggttcgat tactttcttt ttaaatgcgt atactgcacc
    40381 tgcaacggca gcgacagttc ctgcgacacc tgttacaaga cctttagcga atcctttagc
    40441 catgagtctt cctcctttat attctcaatc agccagcctc ctcaagaggt cacatttttc
    40501 tgactgacct ttttgtgtta taataatagt aacgaaaaaa tgggaatttt tcaaggaaaa
    40561 aagatgaaaa caaaaataat tgtgattgtt ggaccgactg ctgttggaaa gacggctcta
    40621 gctattgaag ttgcaaagcg ctttaatggc gaagtggtta gtggagatag ccagcaagtc
    40681 tatcgaggac ttgatattgg gacggccaag gctagtccag aagagcaggc agctgttcct
    40741 catcatttaa tcgatgttag agagataacc gagtcttact cggcttttga ttttgtttca
    40801 gaagctaaga tgactattga ggatattcac agccgtggca agctagccat tatcgccggt
    40861 gggactggac tttatatcca gagcttgcta gaaggttacc acctaggtgg ggagactcct
    40921 catgaggaga ttttagctta tcgagctagt ttggagccat attcagatga ggaattagcc
    40981 catttggtgg agcaagcagg ccttgagatt ccccagttta atcgtcgtcg tgctatgcgt
    41041 gccttagaaa ttgcccattt tggtcaggat ttggaaaatc aagagatctt gtatgaaccg
    41101 ctgattatct gcttggatga tgaacgtagt caactttatg agcgtatcaa ccaccgagtg
    41161 gatttgatgt ttgaggctgg gcttttggat gaggccaagt ggctgtttga ccattcccct
    41221 aatgtacagg ctgctaaagg aattggctat aaggaactct ttccttattt ccgtggagag
    41281 cagacctttg aggaagctcg tgagagtctt aaacaggcga cccgtcgttt tgccaagcgt
    41341 cagctgacct ggttccgtaa tcgcatgcag gtcacctttt atcagattgg agaatctggt
    41401 gtacaagacc gcattttaag ccagataaag gagtttttag atgattgaaa cggagaaaaa
    41461 agaggagcga gtcctgctga ttggtgtgga attgcagggt atggacagtt ttgacctctc
    41521 catggaagaa ttggctagtt tagcgaaaac ggcaggggca gtcgttgtag atagctacag
    41581 acaaaaacgt gaaaaatatg attccaagac cttcgtcggc tctggtaagt tggaagagat
    41641 tgcgcttatg gtggatgcag aagaaatcac tactgtcatc gtcaacaacc gtctgacccc
    41701 aaggcagaat gtcaatctag aggaagttct cggtgttaag gtcattgacc gtatgcagtt
    41761 gattttggat atctttgcca tgcgggctcg aagccatgaa gggaagctcc aagtccacct
    41821 agcccaactc aaatacctct tgcctcgctt ggttggtcag gggattatgc tcagccgtca
    41881 ggcaggggga attggttccc gtggtcctgg tgaaagccag ctggagctga accgtcgtag
    41941 cgttcgcaat caaatcacgg atatcgagcg ccagctcaag gtggttgaga aaaatcgggc
    42001 gactgtcaga gaaaaacgtt tggagtctag cacctttaag attggtttga ttggttatac
    42061 caatgctggg aaatcaacta tcatgaacat cttgaccagt aagacccagt atgaagcaga
    42121 tgagctcttt gcgactctgg atgcgacaac caagagtatt catctgggag gcaatctcca
    42181 agtaactttg acagataccg ttggctttat tcaagatttg ccgacagagt tggtgtccag
    42241 tttcaagtca accttggaag aaagcaagca tgtggacctt ctggttcatg ttatcgatgc
    42301 tagcaatcct taccacgagg agcatgaaaa aacggttctc tccatcatga aagacctgga
    42361 catggaagat attcctcact tgacgcttta taataaagcg gatttggtgg aggatttcac
    42421 gcctacccaa acgccatata ccctcatttc tgccaagtct gaggacagtc gtgaaaactt
    42481 gcaagcatta ttgctagata agattaagga aatttttgaa gcatttaccc tgcgagtgcc
    42541 tttttcaaag tcctacaaga ttcatgattt agagagtgtt gcaattctgg aagaacgtga
    42601 ttatcaggaa gacggcgaag tgattacagg ctacatttcc gagaaaaata aatggaggtt
    42661 agaagaattt tatgactgat attaaaactt tggctctaaa gtatggaggt tatacaagtc
    42721 tggacaaggt ctatctggat cagcttctag ctggtaaaac agagcaggag cagttaacac
    42781 ttattacacc tccgccaagt gttgttaatg cctactttgc agaactctat cagaaaaaaa
    42841 gtcctcaggc tgcgacggat tattttgcag aactcagtca ggaactgaat ctttacaata
    42901 ctgagccaag tttcacccta gaaaataagc cttttattcg gcttaatctg tctggtaaat
    42961 cctttggttt ttgttatgag agtgacggct ttggtcggat tttctctgaa aatgaggaga
    43021 aaatctcgga tgacttgctc tttgaaattg cgcaaatttt ctcccatcaa ttagtctttg
    43081 aagagtctgg taagatttac atgaagcctg tcaaggacga ggaagttgtc agcctagaaa
    43141 gtctcacagc tttgactgat ttggaaagat tggctgatgg tcgaaaacgt ctcaaaggct
    43201 acagccaaga ggatttattg caagaagctg ctgctttttc tggcaaacgc tatttccgat
    43261 cggaaaaccg cacagccatg ttatatattg attaattaga aagtatcgaa tggatattca
    43321 atttttagga acgggggctg gtcagccctc taaagcccgc aacgtttcaa gtctcgccct
    43381 gaaacttttg gacgagatta acgaagtttg gctctttgac tgtggagaag gtacgcaaaa
    43441 tcgcattctg gaaaccacaa ttcgaccacg taaggtcagc aaaatcttta ttacccatct
    43501 gcatggagac cacatttttg gtttgccagg tttcctttct agccgtgcct ttcaggccaa
    43561 tgaagagcag acagatttgg aaatctacgg acctcaagga atcaagtcat ttgtcttaac
    43621 cagccttcgt gtgtcaggtt ctcgtctgcc ctaccgcatt catttccatg agtttgacca
    43681 agattctctg ggtaaaattc ttgaaaccga taaattcact gtgtatgcag aggagctgga
    43741 ccacactatt ttctgtgttg gctatcgtgt catgcaaaag gatctagaag ggacgctgga
    43801 tgctgaaaaa ctcaaggctg ctggtgttcc gttcggcccg ctttttggta aaatcaaaaa
    43861 cggccaggat cttgttttgg aagacggaac tgaaatcaag gcagcagact atatctcagc
    43921 gccacgtcca ggtaagatta tcactatttt aggagacact cgaaaaacgg atgccagtgt
    43981 gcgtctggct gtcaatgcag atgtcctagt tcatgagtcc acttatggca agggtgatga
    44041 aaaaattgct cgtaaccatg gtcactcaac taatatgcaa gctgcacaag tagcggtaga
    44101 agcaggtgcc aaacgcctcc tactcaacca tatcagtgcc cgtttcctct caaaagatat
    44161 aagcaaactc aagaaggacg ctgccacaat ttttgaaaat gtccatgtgg tcaaagactt
    44221 ggaagaagtg gaaatctagc agtcacagaa aggataagta tgcctactat tctcattacc
    44281 ggagctagcg gtggtctagc tcaagaaatg gtcaaactct tgcccaatga ccaactcatc
    44341 ttgcttggta gaaataagga aaaattagcc caactctacg gaaattattc ccatgcagaa
    44401 ttgattgaaa ttgatattac cgacgattca gccctagaag ctctggtaac tgatctttat
    44461 ctccgctatg gcaagattga tgtcttgatt aacaacgctg gttacgggat ttttgaggga
    44521 tttgaccaga ttgctgataa agatattcac cagatgtttg aggtcaatac ctttgccctg
    44581 atgaatctgt ctcgtcacct tgcggctcgt atgaaggaaa gcagcaaagg gcatatcatc
    44641 aacatcgtca gcatggcagg tctaatagct actggcaagt ctagtcttta ctcagcgacc
    44701 aagtttgcgg ctattggttt ttcaaatgct ctgcgactcg aacttatgcc ctatggagtc
    44761 tatgtgacaa cagtcaatcc aggtccaatc cgaacaggat tttttgacca agctgaccca
    44821 gatggaactt atcttaaatc ggttgaccgc ttcctcttag aggcagatgc agtggctaaa
    44881 aagattgtca agattatagg caaaaataaa cgagaactca atctcccgat tttgttgaac
    44941 ctagcccata agttttatac tctctttccc aagctagctg ataagttggc aggggaaact
    45001 tttaattata agtaaaaaga accaatgtgc aggttgttgc tagcctacat attggttctt
    45061 atcatttctc aactatcaaa ctgaacttct tctagtagat agtcgataaa gcgttcgccc
    45121 atcttagata ggctggtttt ctcatgctgg atatagacca gctcaatcgg gtcatcaata
    45181 tccagtggga tagaaacgat attgtctccg tttaggttgc tgttcaaaat ccctgtcgca
    45241 atggtataac catccaaacc aatcaagaga ttaaagaggg tggcacggtc actgaccaca
    45301 atggatttct tgtggtgttc ctgagaaaga atctcttctg aaaagtagaa ggagttgtgc
    45361 gtcccttggt catagctgag gtaagggaaa ttctccaaat cagacagttt caccttgtct
    45421 ttctttgcca gagggttggt cttgctgaca aagatatgcg gttgcgctgt gaagagatgg
    45481 tgggctagca ggtgattgtc atccagcatc ttggttaaaa catcacggtt gtaactgttt
    45541 aagaagagga ccccgacctc actgcggaag ttcttgacgt cgtcgataat ctcccaagtc
    45601 cgagtttcac gaaggaagag ttcgtatttc tccatatcgc ttttcttgag caaagagaca
    45661 aaggcattga ccacaaaggc atagtgttga gacgaaacgc taaagagttc gcggtgggcg
    45721 acaggatttt tatagcgttc ctccagaagc tgggtctgct cgacaacctg acgggcataa
    45781 gagagaaact ccatcccatc acgggtcaag gtgattccct tgggattgcg gataaagatc
    45841 tcaatgccca tttcattttc caaatctcgc actgcattgg agagacttgg ctgagtgata
    45901 aagagttgct tggctgcctc attcatggag ccagtttcga cgattttgat aatataatgt
    45961 aattgttgaa ttctcatgtt tttattgtac catacttgcc ttagaatcgc taaagaagat
    46021 aggaaaataa ggagcattgt atgagtctct tcttgaaaaa aacacaaaat tttgctagaa
    46081 tgagtcttat gaaaacattc tatgatgtgc agcaattcct caaacgattt ggtattattg
    46141 tttacatggg aaaacgctta tatgatattg aactgatgaa gttggaacta tctcggattt
    46201 acgatgcagg gttgatggat aaattagact atctagaggc agaagcagtt cttcgcagag
    46261 agcacaaggt agaattggat tatattgaga aaaatggaga aaagaactaa tggttacttg
    46321 gattttgtgg gcacttatac tagcaatgtt ggcgtggatg ggctttaact atcttcgtat
    46381 tcgccgtgcg gctaaaattg tggacaataa ggagtttgaa gccttgattc gtacgggtca
    46441 attgattgat ttgcgcgacc cagcagaatt ccacagaaaa catatccttg gtgcacgcaa
    46501 tattccttca agtcagttga aaactagtct tgcagcactt cgtaaagata aacctgtcct
    46561 tctctacgaa aaccaacgtg cgcaacgagt tacaaatgca gctctttact tgaaaaaaca
    46621 aggtttttct gagatttata tcctttctta tggcttggat tcttggaaag ggaaagtgaa
    46681 gactagctaa ccttatttcc aaattagtcg aatgatagga tgaagctatt gttttatagt
    46741 ataattaatt tgtataaaat ttaaagagtt cttagaacat gaaagaaaag aagaaaaatc
    46801 cactttttgt gggtatcttg tcgattattc ttggtttgtt atttccaatt gtaggcctga
    46861 ttttgggtat cataggattg gtcttggcta tttcatacca aaaagagtca caattagact
    46921 ataaaataga aaagattctt aatatcttag gaattgtgat ttctgtagtt aactggattg
    46981 tagcaatcgc cttaattttt cggtaaataa aagaaaaaag ctttagtttt aaagcttttt
    47041 ttattttatc gactcatctc taaatagttt ttaatgattt gtaactcttt ttggttcaaa
    47101 gggcggtagt taccttctgc taaatctggg ttcaatgtga agtccccaaa ttggattctt
    47161 ttgaggctag tcaccttaac accaaccgag aggaacattt tcttgatttg atgaaatttt
    47221 ccttctgaaa tggtgataga ggcttgactg agggagggac ttgctgatag aatctctagt
    47281 cttgcaggtt tacagatagt gccatctaaa aagacaattc ccttttgaaa ggcttggata
    47341 tggtcaggtg ttagaagtcc attaacctca acttgataag tcttatcgac atgatattgg
    47401 ggatggagga gttggaagcc caagggaccg ttatcggtca agagaaggag tcctgttgta
    47461 tctcggtcca gtcggccgac ggcatagagc ttgtcagact gaatgtcaga tggaagcagg
    47521 tccatgacgg tcggaagttc cttgtctttg ttggctgtaa cgacaccagc aggtttatga
    47581 agcataagat aggtgtgttc atagccttga atgattcgat cctgaaaaag gagttcttgt
    47641 agtcctgtat cgatattttg ggctagggag cgggctgggc aactatcgac gagaatgtcc
    47701 cctttgagta aggcttgttt catggccttt cggctgattt tttcttgagc taataaatta
    47761 tctaaacgca tactgtgcct atcttatcat aagtcgcttg ctttgaaaag gcttgacgtg
    47821 aaaagaaaag cggagtgaaa acatttacac ttgcttgagt tatgttattt atttgaaatt
    47881 atggtataat cgttcagtta gaaaataaat tttgaatatt atagaggaaa tcatgacaaa
    47941 attaagagaa gatatccgta acattgcgat tatcgcccac gttgaccacg gtaaaacaac
    48001 cctggttgac gaattattga aacaatcaga aacgcttgat gcacgtactg aattggcaga
    48061 gcgtgctatg gactcaaacg atatcgaaaa agagcgtggg attaccatcc ttgctaaaaa
    48121 tactgccgtt gcttacaacg gaactcgtat caacattatg gacacaccag gacacgcgga
    48181 ctttggtgga gaagttgagc gtatcatgaa aatggttgac ggtgttgtct tggtcgtaga
    48241 tgcctatgaa ggaaccatgc cacaaactcg tttcgtattg aaaaaagcct tggaacaaga
    48301 ccttgtccca atcgtggttg ttaacaaaat cgataagcca tcagctcgtc cagcagaagt
    48361 agtggatgaa gtcttggaac ttttcatcga gcttggtgca gatgacgacc agcttgattt
    48421 cccagtggtt tatgcttcag cgatcaacgg aacttcttca ttgtcagatg atccagctga
    48481 ccaagaagcg actatggcac caatctttga cacgattatc gaccatatcc cagctccagt
    48541 agataactca gatgagcctt tgcagttcca agtgtcactt ttggactaca atgacttcgt
    48601 tggacgtatc ggtatcggtc gtgtcttccg tggtacagtt aaggttgggg accaagttac
    48661 cctttctaaa cttgacggta caactaaaaa cttccgtgtt acaaaactct tcggtttctt
    48721 tggtttggaa cgtcgtgaaa tccaagaagc caaagcgggt gacttgattg ccgtttcagg
    48781 tatggaagac atctttgtcg gtgaaaccat cactccgaca gatgcagtag aagctcttcc
    48841 aatcctacac atcgatgagc caactcttca aatgactttc ttggtcaaca actcaccatt
    48901 tgctggtaaa gaaggtaaat gggtaacttc tcgtaaggtg gaagaacgct tgcaggcaga
    48961 attgcaaaca gacgtttccc ttcgtgttga cccaactgat tcaccagata aatggactgt
    49021 ttcaggacgt ggagaattgc acttgtcaat ccttatcgaa acaatgcgtc gtgagggcta
    49081 tgaacttcaa gtatctcgtc cagaagttat cgtaaaagaa atcgacggtg ttaaatgtga
    49141 accatttgaa cgtgtacaaa tcgacactcc agaagaatac caagggtctg ttatccaaag
    49201 cctttctgaa cgtaaaggtg aaatgttgga tatgatttca actggtaatg gtcaaactcg
    49261 tttggtcttc cttgttccag cgcgtggttt gattggatac tcaactgagt tcttgtcaat
    49321 gactcgtggt tacggtatca tgaaccatac cttcgaccag tacttgccat tgattccagg
    49381 ggaaattggt ggacgtcacc gtggtgccct tgtttctatc gatgctggta aggctacaac
    49441 ttactcaatc atgtctatcg aagaacgtgg tacgatcttt gtcaacccag gtactgaggt
    49501 ttatgaagga atgatcatcg gtgaaaactc tcgtgaaaat gacttgacag ttaacatcac
    49561 gaaggcaaaa caaatgacca acgttcgttc agctactaag gaccaaacag ctgttatcaa
    49621 gacgcctcgt atcttgacac ttgaagagtc tcttgagttc ttgaacgacg atgagtacat
    49681 ggaagtaacg cctgagtcta tccgtttgcg taaacaaatc cttaacaaag cagagcgtga
    49741 gaaagctaac aagaagaaaa aatcagctga ataagagcta gaaagagaga aagatggtct
    49801 atttagtcct aggaatttta ctgctcctac tctatgtatt tgcgacacca gaaagcatta
    49861 aagggacagt caatatcgtc gctatggtat gtattttagt ggcactcttg attttattgg
    49921 ttctatcttt tctgaaaatt tttcaattac caacagaaat attcctagca atagccatgt
    49981 tgatcctagc ttactttagt gtgagagaca tcacactcat gccagtcaaa aaaagtaaaa
    50041 gaagataaaa aagagagttt cggctctctt ttttgctagg aattttacaa gattgcaatt
    50101 tatttttgag ttatcaccat ctcttttgtt tggataatat gaatgggaaa aacttgaata
    50161 aaattcttta atggcatcta ttttatattt ggttagtact ggttgcatat tattttgaaa
    50221 taaaactact atataatatt attcatagag gtaatatagt aaaatatcta aaaaattcga
    50281 ttttttcctt gacaacaaat aataaaaatg ttatcctcat cacataagaa agcggtttca
    50341 acaaaagaaa gaggagggtt tattttgttg cattgttgct caaggtgtgc tttttttgaa
    50401 agaaaaaata aaatgaaaac gaaaaaacat agattacttg ctctagttct tatttcaagt
    50461 tttacattat tgggagctgc atcagctgct gtacaatatc cagatggagg agtatggaca
    50521 tatggagaag gttcaggagg tggttgggct ttttcaaatt actatcatgg taaaaaatat
    50581 cattattcat ccatcgtgag cagatgggat ggtcattctg ataaaggaga agctcctgct
    50641 ggaaaaacct cctatgcatg gatttggact aaatggggag aacaagtagc attttactgt
    50701 gattatgact aatcgttcat tgatttaaat cgttcccctt gtaagaaatt acagggggaa
    50761 ttttgtttac aaggagtcta ctatgaagaa actattcata ttattatcaa ctttttttct
    50821 cagcttcttc cttgcttgga ttattgtctt acgtgcgcca caatatttat atgcaagcta
    50881 tgattccgtt tctttacttc gtgtcaaaaa agatactcag gaaccgacgc gtgaggtatt
    50941 tgaacaggaa ttggagaatt ttgcaaactc agaacagagt ttaatagcta gaagaattgt
    51001 agagccgagt aaggatggga cgactcactt tacttatgca acttatggtc agggaacttt
    51061 accaaaagaa ttccaagaag ctagccaaga aagtcgtgaa cgtagtgatc cgctaaatag
    51121 ttatctcctt ttgtcaggct ccttgacgaa agaaaagctt gccgataaat taggagattt
    51181 gggttataaa gcaagtgctg accgaaagat accgccctat tttcttgctt ttcgaatatt
    51241 actaaatccc cttattttaa ttagtttagc aatatttggc ttatctttct ttgctttagt
    51301 gattatcact cggattaagg aaatgagagc agcaggtata aaactctttt ctggtcagac
    51361 tctcttatcc atcatggggc attctttatc tactgatatc aaatggctcc ttctatcagc
    51421 cctcctttcc ttcctaggtg ggggagtcgt tctttttagt caaggtttgt tttatcctat
    51481 cttgttagcc acctatggtt ttgggattag tttctatctg ttgtttttat tggcgatttc
    51541 aattttacta atgctccttt acctaatgag tttgagttac aaagcattag ttcctgttat
    51601 taaggggaga ttacccctta aacgcttgat ggctttaacc ctattgtgtc agttggttgc
    51661 tgtctttaca gtaggctacg ctgttaagac aggtttgatg tcttaccaac gattgaaaga
    51721 acttgaaatt tcaaaacaag catggcagga tagagcagac tattatcaaa tttcttttgg
    51781 cttaggtgat agaggaaaag atacagaaaa tcagagcaag tggtatgcct ttgccaagga
    51841 agcaatcgaa gaagaacaag ctctttatgt aaaggataat ctgctccatt ttgccaatcc
    51901 acaaggaaaa aatgaacagg gagagacact ggatacctat agtccagatg ctaatacgct
    51961 ctatgttagt cccagttatt tggacaagga aaaggtcgtg gtagatgctg agaccaaaca
    52021 gaagttagcc catctccaaa aaggtgagtt tatcctcttg ctcccagaac atttgcgctc
    52081 tcgagaagca gaacttaaga aagtttttga agaaagattg agttattatg gaaaatctgg
    52141 tgaggaggca agtgctcctt tggattatga gatgaaagcg cacgttagtt atctttcaat
    52201 gggagaaaag cggtttgttt ataataacgg tgagaatccc gtatccactc agtatttgat
    52261 tgatccgatt ttagttgtat tcacgccgac ttctacaggt gatagtttta tatccttatc
    52321 tagttggtct atcaatgctg gaaaacaact ctttatcaaa ggatatgaga gtgggctaga
    52381 actcttgaag aaagctggaa tttatgagca agtatcctat cttaaagaag gaagaagtgt
    52441 ttatctaact cgttataatg aagttcaaac tgaaacagca actttaatct taggagctat
    52501 tgtggggata gctagttcct tgttactctt ttattctgtc aatcttctat atttcgagca
    52561 attccgccga gatatcttga ttaaacgaat ttcaggttta cgattttttg aaacacatgc
    52621 tcagtatatg gttagtcaat ttgccagttt tgtatttggt gctagtctct ttattttaag
    52681 cagtcgagac ttggtgattg gcttgctcac tttattagtc tttctagcta gtgcagttct
    52741 gacgctttac cgtcaagcgc agaaagaatc tcgtgtttct atgacaatta tgaaaggaaa
    52801 ataggatgat tgaactaaag aatatatcta aaaaatttgg aagccgtcag ctattttcag
    52861 atacgaatct tcattttgaa ggtgggaaaa tttatgcctt aatcggtaca agtggctgtg
    52921 gtaagacaac actcttgaat atgattggac gattagagcc atatgacaaa gggcaaatca
    52981 tctatgatgg cacttctctt aaggacatca agccttctgt tttctttaga gattacttag
    53041 gatacttatt tcaagatttt ggcttaattg aaagccaaac cgtcaaagag aatctcaatc
    53101 tgggtttagt tggtaaaaag ttgaaggaaa aagagaaaat ctctttgatg aaacaagctc
    53161 taaaccgtgt aaacctctct tatttggatt tgaagcaacc tatatttgag ttatcaggag
    53221 gagaagcaca acgtgttgca ctagcgaaga taattttaaa ggatccacct ttgatcctcg
    53281 cagatgaacc aaccgcttcc ttagatccca aaaactctga ggaattactt tccatcctag
    53341 aatctttaaa aaatccgaat cgaactatta ttattgcgac ccacaatcct cttatttggg
    53401 aacaagtgga ccaagttatt cgagttaccg atttatcaca tagatgataa ggcaagattc
    53461 agttagaaga aagagtcaca aacacacttt gtggcttttt tatttccata aaaatggtaa
    53521 aatagtagga gtagaaatgg agttcgagac atgaaagtaa tagatcaatt taaaaataag
    53581 aaagtccttg ttttaggttt ggccaagtct ggtgaatctg cagctcgttt gttggacaag
    53641 ctaggtgcca ttgtgacagt aaatgatggg aaacctttcg aggacaatcc agctgcccaa
    53701 agtttgctgg aagaagggat caaggtcatt acaggtggcc atcctttgga actcttggat
    53761 gaagagtttg ctcttatggt gaaaaatcca ggtatcccct acaacaatcc catgattgaa
    53821 aaggctttgg ccaagggaat tccagtcttg actgaggtgg aattggctta tttgatttca
    53881 gaagcaccga ttattggtat cacaggatcg aacggtaaga caaccacaac gactatgatt
    53941 ggggaagttt tgactgctgc tgggcaacat ggtcttttat cagggaatat cggctatcca
    54001 gctagtcaag tggcccaaac tgcgtcggac aaggacacgc ttgttatgga actttcttct
    54061 ttccaactca tgggtgttca agaatttcat ccagagattg cggttattac caaccttatg
    54121 ccaactcata tcgactacca tgggtcattt tcggaatatg tagcagccaa gtggaatatc
    54181 cagaacaaga tgacagcagc tgatttcctt gtcttgaact ttaatcaaga cttgacttcc
    54241 aagacagaag ccactgttgt accattttca acacttgaaa aggttgatgg agcttatctg
    54301 gaagatggtc aactctactt ccgtggtgaa gtagtcatgg cagcgaatga aatcggtgtt
    54361 ccaggtagcc acaatgtgga aaatgccctt gcgactattg ctgtagccaa gcttcgtggt
    54421 gtggacaatc aaaccatcaa ggaaactctt tcagccttcg gtggtgtcaa acaccgtctc
    54481 cagtttgtgg atgacatcaa gggtgttaaa ttctataacg acagtaaatc aactaatatc
    54541 ttggctactc aaaaagcctt gtcaggattt gacaacagca aggtcgtctt gattgcaggt
    54601 ggtttggacc gtggcaatga gtttgacgaa ttggtgccag acattactgg actcaagaag
    54661 atggtcatcc tgggtcaatc tgcagaacgt gtcaaacggg cagcagacaa ggctggtgtc
    54721 gcttatgtgg aggcgacaga tattgcagat gcgacccgca aggcctatga gcttgcgact
    54781 caaggagatg tggttcttct tagtcctgcc aatgccagct gggatatgta tgctaacttt
    54841 gaagtacgtg gcgacctctt tatcgacaca gtagcggagt taaaagaata atatgaaaaa
    54901 aattgtcttt acaggtgggg ggacggttgg acacgttacc ctcaatcttt tgttaatgcc
    54961 caagttcatc gaagatggtt gggaagtcca ctatatcggg gacaagcgtg gtatcgaaca
    55021 ccaagaaatc cttaagtcag gtttggatgt caccttccat tctattgcga ctggaaaact
    55081 gcgtcgctat ttctcttggc aaaatatgct ggacgtcttc aaagtttgct ggggaatcgt
    55141 ccaatcgctc tttatcatgt tgcgacttcg tccacagacc cttttttcaa aggggggctt
    55201 tgtctcagta ccgcctgtta tcgctgcgcg tgtgtcagga gtgcctgtct ttattcacga
    55261 atctgacctg tctatgggct tggccaataa aatcgcctat aaatttgcga ctaagatgta
    55321 ttcaaccttt gagcaagctt cgagtttgtc taaggttgag catgtgggag cagtgaccaa
    55381 ggtttcagat caaaaaaatc cagaaccaga tgaattggtg gatattcaaa gccactttaa
    55441 tcataaattg ccgactgtat tgtttgttgg cggttctgca ggtgctcgtg tctttaacca
    55501 attggtgaca gaccataaga aagaactaac agagcgctac aatattatca atctaactgg
    55561 agattctagc ctgaatgagt tgagccaaaa tctttttcgt gttgactatg tgaccgatct
    55621 ctatcaaccc ttgatggaat tggctgatat tgttgtgaca cgaggtggtg ccaatacgat
    55681 ttttgagctc ttggcgatag caaaattgca tgtcattgtg ccgcttggtc gtgaagctag
    55741 tcgtggtgac cagcttgaaa atgcagctta ctttgtaaaa aaaggctatg cagaagacct
    55801 tcaagaaagc gatttgacct tggatagttt ggaagagaag ctttctcact tactaagtca
    55861 caaggaagat taccaagcta agatgaaggc ttctaaggaa ttgaaatctc tagcagattt
    55921 ttatcaattg ttgaaaaaag atttatcata aggaaagtaa atgtcaaaag ataagaaaaa
    55981 tgaggacaaa gaaatcctcg aagaattgaa agagttatca gaatggcaga aacgaaacca
    56041 agaatatcta aaaaagaagg ctgaagaaga ggcggctcta gctgaggaga aggaaaagga
    56101 aagacaagct cgaatgggag aagaatctga gaagtcagag gacaaacagg accaggagag
    56161 tgaaacagac caggaagatt cagaatcagc taaggaagag tctgaagaaa aagtagcatc
    56221 ctcagaggct gacaaagaga aagaagagaa agaagaacca gagtctaaag agaaggagga
    56281 acaggataaa aagctttcta aaaaggctac aaaggaaaaa ccagccaaag caaagattcc
    56341 tggtatccat atcttgcgag ccttcacgat tttatttcca agtctgcttt tattgattgt
    56401 ctctgcctac ttgctcagtc cttatgcgac catgaaagat attcgtgttg agggaacggt
    56461 gcaaactaca gctgatgata ttcgacaggc ttcaggcatt caggattcgg attatacgat
    56521 taaccttctg ctagacaagg caaaatatga aaagcagatt aagtctaact attgggttga
    56581 atcagctcaa cttgtctatc aatttccaac taagttcact attaaggtca aggaatatga
    56641 tattgtggcc tactatattt ctggtgaaaa tcattatcct attctttcca gtggtcagct
    56701 tgagactagt tctgtgagtc tgaacagttt accagaaact tatttatcag ttctctttaa
    56761 tgatagtgaa caaatcaagg tttttgtctc agaacttgct caaattagcc cagaactcaa
    56821 ggcggctatc caaaaggtgg aattagcccc aagcaaggtg acatccgatt taattcgatt
    56881 gaccatgaat gattcggacg aagtcttggt tcctctatct gaaatgagta agaaactgcc
    56941 atattacagt aagattaagc cacaattgtc agaaccgagt gtggtcgaca tggaagctgg
    57001 aatttacagt tacactgtgg cggataaatt aattatggaa gctgaggaaa aagccaaaca
    57061 agaggccaag gaagccgaga aaaaacagga agaagaacag aaaaaacaag aggaagagag
    57121 caatcgaaat caaacaaatc agcgttcatc gcgtcgctag gtttaccttt tctcttatag
    57181 ttctttagtg accatgtttt tacttgacaa gtgctagtag aaataataga atagtaaaaa
    57241 acctttaaag cagtccagag aggcagctaa ggttagacgg tgaaagggtg gagactaccc
    57301 atttttcgtg gaaccttgct gttggcaggt tccttttttc gtggcttctg ttggccagac
    57361 tctctcacta gtaaaggcaa aaggagaaac ctatgcgaga acatcgtcca atcattgctc
    57421 ttgattttcc taattttgag gcggtcaagg aatttttagc tcttttccca gcagaagaaa
    57481 gcctttatct caaggtaggg atggagcttt attacgcagc ggggcctgag attgtgtcct
    57541 acttaaaagg tttgggtcat agtgtctttt tggatctcaa acttcatgac attcctaata
    57601 cagtcaagtc agccatgaag gtcttgtctc agcttggtgt cgatatgact aatgtccatg
    57661 cggctggtgg tgtagagatg atgaaggcgg cgcgtgaagg tcttgggagt caagccaaat
    57721 tgatcgctgt aactcagctg acatcaacgt cagaagctca gatgcaggag tttcaaaata
    57781 tccaaaccag tctgcaagag tctgtgattc actatgccaa gaagacagct gaagctggct
    57841 tggatggtgt tgtttgctcg gctcaggaag tacaagtcat caagcaggct accaatccag
    57901 attttatctg tctgacacca gggattcgtc cagctggtgt tgcagttgga gatcaaaaac
    57961 gagtcatgac acctgctgat gcctatcaaa tcggcagtga ctatatcgta gtgggacgtc
    58021 ccattaccca agctgaggat cctgttgcag cttatcatgc catcaaggat gaatggacac
    58081 aggactggaa ttaaagaact agattagaaa aataaaagga gaataccatg acacttgcta
    58141 aagatatcgc tagccacctc ttgaaaatcc aagccgttta cctcaaacca gaggaaccct
    58201 tcacttgggc atctggtatc aagtcaccga tttacactga taatcgtgtg acactagcct
    58261 atccagaaac tcgtacccta attgaaaatg gttttgtgga agctatcaaa gaagcctttc
    58321 ctgaagtaga agtgattgca ggaactgcaa cagcagggat tccacacgga gccattattg
    58381 ctgataagat ggacttgcct tttgcctaca tccgtagcaa accaaaagac cacggagctg
    58441 gtaatcaaat cgaaggtcgc gtagctcaag gtcaaaaaat ggtagtggtt gaagacctta
    58501 tttcaacggg tggttcagtt cttgaagctg tagcagcagc caagcgagaa ggagcagatg
    58561 tacttggagt tgtagcgatt ttcagctacc aattgccaaa agcagataag aactttgcag
    58621 atgctggtgt taaacttgtg acgctttcaa actatagcga gcttatccat ctagcccaag
    58681 aagaaggtta catcacgcca gagggccttg atcttctaaa acgctttaaa gaagaccaag
    58741 aaaattggca agaaggttag gtcagtaaga taaagagaga cgaggctacc gagtctcttt
    58801 taccatttta tttaaaatat gacaatattt taaataaaat aattgacaac gctttctttt
    58861 attgatataa tgaaaatgta atatgtatca aattgatcaa tcaactatct tgtttatcac
    58921 ttcttaagag gacgatgtca tgaaaagaag aaaaatatat tccttttttg cgtagttaca
    58981 attgcatcta gtttgtttct ccctacagtt ttagctagac agattggaaa ttatgattta
    59041 acgttgccgc gttggggttc ggatacaact agtgagcttg agaaagaaaa cgcctctgct
    59101 ggaattaata acagtgacag cactggtggc ggtaaaaggt taagtacctc tattcgtagc
    59161 gcctatagtg ggtcagatat taccccggta tattcattgg ggtctggctc taggattgtc
    59221 atgtactata atggaggtgg tgacaattat attggttctg gtactagatt agctatggcg
    59281 ccacaatttg gaaatcatgt aagaattcat acttcaggtt cttggagtcc agattcttat
    59341 taacttactt gtcagagtaa gccttaaaga tggttgattg tgggtgtagc atgaaaaaag
    59401 aatgctacac cctattttta ttataaggag gagtaaggat ggaatttttc atttgtaatc
    59461 ttgtacgagt cgttcaatca cctcgatttt atatgtcttt atttttgacc cttctttgca
    59521 tgagtttagg aaatttcctt gctttcaatg gtatttataa aattgaaggt ttatcgattt
    59581 tttttgccgc ttcttctatt cgaggatttt caccgattag cctagtagct gcacttatct
    59641 gtacactgcc ctattctagt cagataatag aggatgctga gagtcatttt ctaacagcac
    59701 aattgtgccg aatttctaaa aagaagtatc tggctattgt aggtagtact gcaattattt
    59761 cttcttttct agtctttttt ctcccctatt tattattatt aggaattaat cttttagtga
    59821 ctccttatca ggaaatttat attggagatt atagtggtgc cttaaaagaa ttatttgatt
    59881 ctaatcagtt gctctatagt cttgtgacga ctctctggta tggagtttgg ggcgctgtgt
    59941 tctctatttt tggactagct agtgctttgc tagtgaagaa aaaaatagga gctattttca
    60001 tcccagttgc ctatatgatg gttggtggta ttttttgggc tattttaggg ctatcttact
    60061 tagaacctgt gacaacatta gctttgggat atcagaaaga tatcagtctt tccttagtta
    60121 gtgggcatct tgcttttatt ttatttgtta gttgtttggt tgtttatggt acattttttc
    60181 tacattcaga ggactatgta taatgaaaca atttgttcaa ttttacaaaa aagatttttt
    60241 atcagtattg gtttatttta tattactgct atcctgtgtt ttatctagta cagtatattt
    60301 attgcgctgt cgccaatatt caatccatcc aaatgtatta gaatggatct tagttttact
    60361 tcaagatatg acgactggag tatattgctt tccgttcaca tatatattat tcttttttta
    60421 tttgatgaat aactatttta ataggttgga gtgtcgtatt cgtctgaaat caattaagca
    60481 ctttaccagt tttagtttca aattagcagc tcttagtacg gggatttgga cggcgacttt
    60541 atttttattg atttttctga ttgcatttag taatggtttt agcttctctt tggagataaa
    60601 ggaggttgat tttttaagag aattttatgg tataagtatt gcaaacaatg ctagtttctt
    60661 tataggattt tttttctctt atatagcata ctatttcttt ttatccttac ttactattag
    60721 cagtttttct tggtttaaaa aatcaaacat gagcttagta tttctgttta cttttttatt
    60781 tgtagaatcc ttattctgga tttatcagtt ggacaatggg ataattggat tattgccaat
    60841 ttttcagtat atggtaaatt ccaatccgta tgcattgatt tattggctta cattactatc
    60901 tatcataatt ccattgactg tattttctgt tcatagaaac tggaggagag tgtaaaagtt
    60961 ggaaatggga aagttaagta gtcacatgtg gaggttgaat cagataatct ataccaagta
    61021 cttttggggt tatgttcttt tttggatatt gatttgttta ggattatggt attggttaga
    61081 aggaaatgat agacttgtta tagaaatttt aaaagggcct aatctgagtc aaaactcttt
    61141 tttagtctta tctatatggt tgcttcattg gtttattatt catacatttt ttctagcaat
    61201 tgtatatcgt agaagagcat ccgatttctt tatggaagtg attcgatttt cttctattaa
    61261 gctctggatt aggtatcaga tttggacctg ttttctttat ggactcattt taatcatggt
    61321 aaaagttcta gtgattcaat ttatgttaca gttaccaaac tgggatatag gagttttgtt
    61381 tatagttgat tctttgaatg cttgtgtgtt agtcttgttt tgctttatgt tatacgcact
    61441 aggagcgaat gagcaaatga acttttcttg tgttagcttc tttttactca tgattgtgtt
    61501 tggtggtcta tttgtaggaa atcgaactaa ttatctattt tatattttaa atcgagggaa
    61561 tggagatata ggacgagatt tatttcttca gttgctattt ttagtctttc tttttaaaag
    61621 cattttctat ttcactcgtc aaaagaggag gtttatagaa tgaatgaaat aattacatta
    61681 aaaaatattc agttggaatt aaaaaaaaca tgtgtttttc aaaaccttaa ctttagttgt
    61741 aaacaggggg aaattatagg aattactggt gcgaatggct cagggaaaag tgtattgttt
    61801 aaattaatag ctggtttata tagtccgtct tatggagaag tgttaatcaa tggggaaaat
    61861 attgttcctg agagaaaaat tccagctaat ttgggagctt tgattgaaga acctggtttt
    61921 ataaattatt atagtggctt taagaattta caatatttgg caagcatacg aggagtagtt
    61981 ggtaatcagg aaatcaatga tacactgaaa atagttggtc tatatgagca aaaagaccag
    62041 aaagttaaaa cttattcgct aggtatgagg aaaaagctag ggattgctca agcaattatg
    62101 gagaatccct ctattctttt actagatgaa cctatgaatg ccttggataa atcaagtgta
    62161 gaaaatatga gaacattgtt tagaaagctc tctagtgaaa aagggacaac aattttgatt
    62221 gctagtcata gtgaagagga tattcgtatc ttatgtgata aagtatatgc aatagaagat
    62281 aaagtatgta cactgtgttc agattgaaca tcttagatag actcaggatg ttataggtga
    62341 aatcttaaaa agggattgga tcttaaaatc cagttccttt taagagttaa tgactaatca
    62401 acttttccac cttcaacaac caggtcatct gctttagcag cgtcaccgta ggttgggtga
    62461 agtgtttttt cataggcctt gtggaagaag ttttccttgc ctaatttttc aatatcttta
    62521 ttgatgaagt ctagcaattc ttggttgcct ttttgaactg ctgccgcaat ggtatcggga
    62581 tcaccgaggg aagtaattcc tacttcaaat cctttatttt caagcgccca agctagaact
    62641 tccgtattgt cagttgaaaa ggcatctcca cgtccgtcaa gaagagcttg gtaagagtca
    62701 ctgtattggt cgtatttttg gagtttgatt tctggatgat tcttttcaaa ataagtctca
    62761 gcagtcgttc cttttgtgac aattaaggtt ttaccttcaa gttgtttgac gtctgtaatg
    62821 agaccagtct taggtgatac gacacccaga gaaactttca tatatggaag ggcaaaatca
    62881 acttgtttct tacgttcgtc agttactgta aagttagcaa gagtaatatc taccttgttt
    62941 gaaatcaagt attccgcacg gttggcagca tcgactgaaa tgtatttaac cttgacacca
    63001 aggtcttgag ctagttggtt ccctagttca atatcgtagc cttggtaaga accatcattg
    63061 tcaacgtagc caaacggttt tttatctcca aacacggcga ttcgcagttc accgcttttt
    63121 ttgttttcat cgatagtgcg agctttggca gttgtttttc cagaggatgg accagcgttt
    63181 ccacctgagc tacaagcagt gataaagata agggcaaagg caagtgctaa aacagttaag
    63241 agtggtttga atagtttcat aagaatctcc tttatagata tgagccgaat tggctaaagt
    63301 caaagacgtt taaaaattcc tgggctcgtt tggtttgcgg attggtaaag aaggcttgag
    63361 ctgttccttc ttcagcgatt ttcccttggt cgaggaagat aatccggtca gcaatggctt
    63421 gggcaaactg catttcgtgg gttactaaaa tcatggtacg gccttcttgg accaaatcat
    63481 tgataagttc cagcacctca cgcaccattt ctggatccag cgaagcagtc acctcgtcaa
    63541 aaaggatgat ttctggatgc attaggaggg cacggacaat tgcaacacgt tgcttctgtc
    63601 caccagataa ttgacgggca aagctatgtt gtttatccag caaaccgaca cgatctagta
    63661 attgcaaagc ttcttccgtt acttctttct tgtcccttcc ttgagttttg atagggccta
    63721 ggatgaggtt ttgtaagaca tccagatggg gaaagagttc ataactttga aagaccatgc
    63781 caatcttttg gcgaactagg tgaaaatctt ttttattttc aacgatagac tgaccatcca
    63841 gaaaaatatc tccaccttga atactttcta agccgttgag gcaacgaagg agggtacttt
    63901 tcccacaacc agagggccct aggatgacaa caacttccct tttttgattt ctagagaaag
    63961 tccttggagg atgggattgt ctccgaagga tttttttagt tccttgattt ctaagatagt
    64021 ttcagacatt tagtttctcc aatgtttttc taagtgagtg gatagtttgg aaatagggta
    64081 gcaaactgcg aaatataaga ctagaatggt tccataaatc caaaatgaag cagttgggat
    64141 ggtcaggcga ttgctatcga tgatttgttg tccaactttg gtcacttcca caaccccaat
    64201 caaaacaact aatgaagtgg ttttaatcat ccgagtgaca agattgatag cctgcggtag
    64261 cagtcttctt aagacttgtg ggatgatgat gtggtagtaa agttgaacat tagtcaagcc
    64321 gagtgcctgt ccactttcaa actgatgttt agggagagaa gtgatagctc cacgtaccaa
    64381 gtctcccatt tcagctgttc cccagagggt aaaaacgata atagctgaag tctcacctga
    64441 gatattgata ttaaagtttc gagctaagcc aaagtaaacg atgaagagta gcaccagctg
    64501 gggcatgata cgggtaaagt ccagatacaa tcgtgttaaa aatcgtatga ttctagaatg
    64561 ggaggtcatg atgattccca tgactgttcc gaacatcatg gataagagga cagacaggat
    64621 ggatatctca atcgtaacgc ccaatccctg taagattctc aggagattat ttccctgaaa
    64681 gagtacttgg attcccgaat cctgcatggc ggagcctcct ttctatccag ctaaagacca
    64741 gtgagatggg tagcagcatg atcagataag caactaccaa catagctagc gcaatgtctg
    64801 tctcatagta gagaccaatc aaatccttgg cgacatacat gaggtcggcc aaagccactg
    64861 ctgagaaaac agaggtttcc ttgataagga aaatgacatt ggcactaaag gaggggagtg
    64921 ccaccgctgt tgcttgcgga agaaccacat agcgaaagac ctgtagaggt gtcagaccaa
    64981 tagcgaggcc aatctcctgc tgggtttgac tgatggcttc cagcccactt cggaaagatt
    65041 ctgccatata ggatcctcct aaaaagacaa gcccaagcgt tgcacagact tctgaagata
    65101 ggacaatccc gattcgggga agaccgaagt agagaaagaa gagatgaatc aaaaggggcg
    65161 tattacgtga caattcaatg taggctgtcg ctacttgcgc caaaacaggg attcgataat
    65221 gtcggatgat actaacgatt aaaccgagca gaaaggatcc caaaattccc caaactgcaa
    65281 tatgcaaggt cagaaagaat gccttttgat atagtggtag atattgttca acaatggacc
    65341 aatccaaaaa tagaacctcc catctagaaa taatacagtt attgtagcac ttaaaatctt
    65401 ctttggataa tatctatttt ttattgccgt tataaggatt ttttaccata gacataaaat
    65461 ttctgaaatt tccaaacaaa atatttgaaa agttttgaaa aagagttaag atatttttgt
    65521 aatatacaaa gtgaacgctt acttattaag gagggcattt tatgtcatac aaaacaagca
    65581 atgcagaagg tcatgtagat ttcatcaata cctatgattt ggagccaatg gcgcaacaag
    65641 ttattcctaa agcagcattt ggctatatcg ctagtggggc ggaagatact ttcacttctt
    65701 tccagtgatt ttagcgtcag gttcttttta gtttttaaag attatccgtg aatttcttgc
    65761 ttatttatga taaaatgggg tatcgcaaaa aatgactcat cgtattcaat tttgagtaaa
    65821 actaggagga tcccatgtct acagaacata tggaagaact aaatgaccag cagatcgttc
    65881 gccgtgaaaa aatggctgcg ctccgcgaac aaggaatcga tcctttcgga aaacgttttg
    65941 aacgtactgc aaattcacaa gaattaaaag ataaatatgc caacctcgat aaagaacaat
    66001 tacacgataa aaacgaaaca gctactatcg caggacgctt ggtaaccaaa cgtggtaaag
    66061 gaaaagttgg ttttgcccac cttcaagacc gcgaaggcca gattcagatc tacgttcgta
    66121 aggatgctgt cggtgaagaa aactacgaaa tcttcaaaaa agcagacctt ggtgacttcc
    66181 ttggtgtcga aggtgaagtg atgcgtacgg atatgggaga actctctatc aaggcaaccc
    66241 acatcacaca cttgtctaag gctcttcgtc ctcttcctga gaaattccat ggtttgacag
    66301 acgttgaaac aatttaccgt aaacgttacc ttgacttgat ttctaatcgt gaaagctttg
    66361 aacgctttgt cactcgttca aaaatcatct ctgaaatccg tcgttacctt gaccaaaaag
    66421 gattccttga agtggaaaca cctgttcttc ataatgaagc cggtggtgct gctgcccgtc
    66481 catttatcac ccaccacaat gcccaaaaca ttgacatggt gcttcgtatc gcgactgagc
    66541 ttcacttaaa acgccttatc gtgggtggta tggaacgtgt ctatgaaatt ggccgtatct
    66601 tccgtaacga aggaatggac gctactcata accctgagtt cacttctatc gaagtttacc
    66661 aagcttatgc agacttccaa gacatcatgg acttgactga aggcattatc caacacgctg
    66721 ctaaatcagt caaaggtgat ggcccagtca actaccaagg tactgaaatc aagattaacg
    66781 aaccatttaa gcgtgttcat atggtggatg ctatcagaga aattactggt gtcgatttct
    66841 ggcaagacat gactttggaa gaagctaaag ctatcgctgc tgagaagaaa gttccagttg
    66901 agaaacacta cactgaggtt ggtcacatca tcaatgcctt ctttgaagag tttgttgaag
    66961 aaactttaat ccaaccaacc tttgtctatg gacatccagt agctgtatct ccactcgcta
    67021 agaaaaatcc tgaagaccaa cgctttactg accgtttcga gctctttatc atgactaagg
    67081 agtacggtaa tgcctttact gagttgaacg acccaatcga ccaacttagc cgttttgaag
    67141 cccaagctaa agctaaagaa cttggtgatg atgaagcgac aggcatcgac tatgactaca
    67201 tcgaggctct tgaatacggt atgccaccaa caggtggttt gggaatcggt atcgaccgtc
    67261 tctgcatgct cctcactgat acaacaacta tccgtgatgt attgctcttc ccaacaatga
    67321 aataaattct taccctctgg ctcttaccag aggatttttt gattcaaaaa gagactgaat
    67381 ttaaggagaa aatgaagtgt agtatattga agttgaaata gtacactttg atttctaaga
    67441 cattgttaga aattggttta aattccctaa tcaatttgtg catgttttat ttcattttac
    67501 gatagtacgc tgaaactgtt caaaaagtac tagaaattga cttggattcc ccaattgatt
    67561 tgttcagatt cactataaat aaaaaattaa taagtgggat aggaagttag cgtcaactag
    67621 gatagtatct tgcttaaaca gtatatatgg gactgatata agtccatagg tcctattaga
    67681 ggatgttctg gtgtcttatt cacttgtttt tttatagtat tagtagatag aatccgcaaa
    67741 taaaaaagta gttcaaatgc ctggcagcaa aaaatctcaa cgattcactt aatatagact
    67801 aaggtttaga gtttaaggaa agtagggcta gtatattgta tgaaaaaata agatggtttt
    67861 taagcaaaac tcttgaaaat gattgaaaaa agagttatta tagttgtgta gtaaaaagca
    67921 aacgcttact taatcaagga gggcatttta tgtcatacaa aacaagcaat gcagaaggtc
    67981 atgtagactt catcaatacc tatgatttgg agccaatggc gcaacaagtt attcctaaag
    68041 cagcatttgg ctatatcgct agtggggcgg aagatacttt cactttaaga gagaatatcc
    68101 gcgcctttaa ccacaaactc atcgttcctc atacactttg cgatgttgaa aatccaagta
    68161 cagagattga atttgcaggt gaaaaactat cttcaccaat cattatggcg cctgttgcgg
    68221 ctcataaatt ggcaaatgaa cagggggaag tggcgactgc gcgtggtgtg catgagtttg
    68281 gttctcttta tacaaccagc tcttactcta ctgttgacct tccagagatt tctgaagccc
    68341 ttcaagggac cccccattgg ttccaatttt actttagtaa ggatgacggt atcaaccgcc
    68401 acatcatgga ccgtgtgaag gctgaaggtt ataaagcgat tgtcttgacg gcagatgcta
    68461 ctgtaggggg gaatcgtgaa gtggataagc gtaatggttt tgtcttccca gttggcatgc
    68521 cgattgttga agaatacctg ccagaaggtg ctggtaaatc aatggacttt gtttacaaat
    68581 cagctaaaca acgcttgtct ccacgcgatg tagaatttat cgctgaatac tctggtcttc
    68641 ctgtgtatgt caagggacca caatgccgtg aggacgttga acgttcgctt gctgcaggag
    68701 cttctggtat ctgggtaacc aaccacggtg gtcgtcaaat cgacggtgga ccagctgcct
    68761 ttgactcgct tcaagaagtg gcagaagcag ttgatagacg tgtgccgatt gtctttgact
    68821 ctggtgttcg tcgtggtcaa cacgtcttta aagccttggc ttcaggagca gacttggtag
    68881 ctattggtcg ccctgttatt tatggcttgg ctctcggtgg tagtgtcggt gtgcgtcaag
    68941 tctttgaaca cttgaatgcg gaattgaaga cagttatgca attgtctgga gctcagacca
    69001 ttgaagatgt caaacacttt aagctccgtc acaatccata caacccaacc ttcccagttg
    69061 accctcgtga cttaaaattg tattgataaa acagattgcc tccactgaat gtggaggttt
    69121 ttcttcgtgt attggaagaa taaattgcta tcgaaaacta tagtaaaatg aaataagaat
    69181 aggacaaatc aatcaggaca gttaaatcga tttctaacaa tgttttagaa gtagaggggt
    69241 actattctag tttcaatcta ctatatataa agatattttt cggttaaata tcttgctaag
    69301 gctttcattt tttgctatac tggttcagta attaaataat agagacattt ggggtgcttt
    69361 aggctgagat aatacccatt gaacctgata cagttaagac tggcgaaggg aaatgtgaac
    69421 agttttttcg tatggtgaaa tgaatggtct aatcttgtaa gtcaactcta attcttgatt
    69481 gtaattggag ttttttgttt atataaactg gataggcttg tttagttagc tctctgcaaa
    69541 tactctcgat gtgttttaaa aggatcaagt ggaattacga ttttgcttga tatttcttgg
    69601 tgttttatta attactaaca agtaaagaga ggagaagtaa atatggaaac acaagactat
    69661 gcatttcagc caggtttgac tgttggagaa ttattaaaaa gcagtcagaa ggattggcag
    69721 gctgcaatca atcatcgttt tgttaaggaa ctttttgcgg ggacaattga gaataaggtc
    69781 ttaaaggact atctgattca agattatcac ttctttgatg ccttcttatc catgctgggt
    69841 gcctgcgtag ctcacgcaga taaacttgaa tccaagcttc gttttgccaa gcaactaggc
    69901 tttcttgaag cagatgaaga tggttatttc caaaaggctt ttaaagagtt aaaagtagca
    69961 gagaatgact acctagaagt gactttgcac cctgtaacaa aagcctttca ggatctaatg
    70021 tattcggcag tggcttcatc agactatgcc catcttttgg ttatgctggt cattgcagaa
    70081 ggtctctatt tagactgggg ttctaaagat tttgctctac ctgaagttta tattcattcg
    70141 gaatggatca atctccacag aggtcctttc tttgcagagt gggttcaatt tctggttgac
    70201 gaactcaatc gtgtcggtaa aaatcgagaa gatttgacag aacttcagca acgctggaat
    70261 caagcagtcg ctttagaatt agcttttttt gatattggtt acgatgtcta gagaaggctc
    70321 atgatattta caaatttgat gaggtaagac tcttcgaaaa tctcttcaaa ccacgtcagt
    70381 ttcaccttgc cgtaggtatg gttactgact tcgtcagttc tatccacaac ctcaaaacag
    70441 tgttttgagc aacctgcggt tagcctccta gtttgctctt tgattttcat tgagtataaa
    70501 tcattcaacg taaatgaaaa aaatttctta acgaaagata gagataaatc gaaatcagta
    70561 gatcgtataa agtgtaaagg aaggatttca atatgacaag tttaaaatta ttaaaagaaa
    70621 aagtaccatt ggtcatttgt ataaccaatg atgtagtaaa aaatttcaca gcaaatggat
    70681 tagtagcact gagcgtctca ccagccatga gtgagtttcc agcagattta gaggatttgt
    70741 taaagtatgc tggtggttta ttaataaaca taggaacatt gacagatgaa aattggaaat
    70801 tataccaagc tgctctgaaa attgcggaga aatataatgt cccagcagtt ttagatcctg
    70861 tagcctgtgg agcaggagaa tatagaaaaa aagtagcaga tgatctaatc aacaattata
    70921 aactagcagc gattagagga aatgctggcg agattgcctc tttagtagga atagatgtgg
    70981 catctaaagg agtagatagt gcgggcgtag ataatattga cgaaattgct ctagcagcaa
    71041 atgagaagtt caatattcca atagtagtaa caggtgaagt ggatgccatt gctgttaatg
    71101 gagaagtggt aacgattcat aatggtagtg ctatgatgcc gaaagtcatt gggacaggat
    71161 gcttattagg agctgtagta gcaagcttta tcggactaga aaaaggtcaa gaattgaaat
    71221 cattagaaac agcaatgtta gtttacaata tcgctggaga aatggcagaa aaacgtccaa
    71281 atggacatct tcctgggaca tttaaagttg aatttataaa tgccttatac gagattacag
    71341 atgaagatgt aaaggaattc aaaagagtga agtaagatgt ttcataaaga attactaaaa
    71401 ctatatttta tttgtggaac gactacttgc caaggaaaaa atctatatac agtcgttgag
    71461 gaagccttaa aaggtggtat aaccttattt caatttcgag aaaaaggtga gggtgcttta
    71521 gaaggcttag aaaaacttga gctagctatc caaattaaag aactttgtaa aaaatacaat
    71581 gttccattta tcgttaatga cgatatagat ttagcaatgg aaattgacgc cgatggcgta
    71641 catgttggtc aagatgatat tggtgttgat gaaattagaa aattgatgcc agataaaata
    71701 attggtcttt ctataagaaa cgaagaagaa tttcaacaat caaaagttga atatgtagat
    71761 tatgtaggtg ttgggcctgt atttgatacc cagtcaaaag atgatgctgg tggtgctata
    71821 ggttatgaag gtcttgaatt gatgagaaaa ctattgccac aaatgccttt agttgcaatt
    71881 ggtgggatac agacgaaaca tattaaagac attataaaga ccaatgttga cggcgtttca
    71941 atcatttcgg caatatcgta tgcaaaaaat atagaaaaaa ctgttcggga aatgagtgaa
    72001 caatagatat ctatccttgg attctaagta agtaggattt tcctttttta aaaagctatg
    72061 tctagattca gcttgaatgg ctaattcatc aaacaggtca tttgtttttt gcaaaagaaa
    72121 gatctgctgt ctttgtgagt gcaaggctgt atttccagtt caatttcttg aactagtata
    72181 aaatgtgtgt tataataatc acataattaa ataataaaga catttggggt gctttaggct
    72241 gagatgatac ccattgaacc tgatacagtt aagactggcg aagggaaatg tgaaatgttt
    72301 ttttcgtatg tcgaaaagaa ctgtctaatc ttgtaagctg aactctaatt cgtatctgta
    72361 attagagttt tttcttttac gaaactggat gaagatgata tagtagattg aaataagatg
    72421 cgaacaaatc aattagaaaa ttcaaattaa tttctagaaa tattttagca ttcttgtgta
    72481 ctgttctaaa ttcagtctgc tatacaaagt atttaggtcg gtcttcttga gtgccccact
    72541 tttctttaaa aaaaggagtt ttttatgttg aaaaaatggc agttaaaaga tgttatcttg
    72601 cttgctttct tgtctatctt ttttggtggg gttttcgttg gttcaggata tgtgtataat
    72661 attctcagtc tactcttaac acctcttggt ttgcaggcct ttgccaatga aatcctcttc
    72721 ggtctctggt gtatggctgc gcccattgct gccatctttg ttccgagagt cggaagtgca
    72781 atgattggag aagtgctagc tgcgcttgct gaagtccttt atggtagcca atttggtcta
    72841 ggagctcttt tgtctggctt ggttcaaggt ttgggaagtg aatttggttt tatcgtaact
    72901 aagaatcgct atgaaagttg gctctctcta actgctaata gtattgggat tacgcttgtt
    72961 agctttgtct atgaatacat taagttaggt tactacgcct tttccctttc gtttgtcctt
    73021 tccttgcttg tggtacgttt tatttctgtt tatttcttct gtaccatctt ggttcgtgcc
    73081 attgtcaaac tctatcatca gtttgcaact ggaggaaaag catagatggg tctggaacta
    73141 cgagcgattc agtccccaat cttctctgag ccgtttgatt ttacttttca tgtgcaagcc
    73201 tttaccttgt tagttgggag tagtgggtct ggaaaatcaa gcctctttca aatgattgcc
    73261 caagttagtt ctcttcccta tagcggtcaa gtcctgatag atgggagtga ggtcagtcag
    73321 ctttctatcg tcgaacgtgt ccagaaggtt ggcattctct ttcaaaatcc caatcatcaa
    73381 tttaccatgg agaacttgtt tgaggagttg attttcacct tggagaatat cggctatcac
    73441 cttcaggaaa ttgattctaa aatagcagag gttgtccagc aatgtcgttg cgaggcaatc
    73501 ttacaccgtc ccattcatca cctatcaggt ggggaaaagc aaaaagcagc gctggctgtc
    73561 ctctttgcca tgaatcctag ggtctatctc ttggatgagc ccttcgcttc tattgcccgc
    73621 aagagcagaa tcgagatatt ggagattcta aaagagttgg ctcttgatgg gaagacagtt
    73681 attttgtgcg accatgattt atctgactat aaagcctata tcgaccatat ggttgagcta
    73741 agagacggaa aactaaggga agtgtttcaa atcccttcct atgagatgac acaggttgct
    73801 tcaaaggaag ttgcttctag cccggaacta ttccatatga accgtgtgac tggtgagctt
    73861 ggtaatcgcc ccctcttttc aattgctgat ttcacattct atcaagggat ttcctgtatc
    73921 ctgggtgaca atggtgtcgg gaaatcaacc ctctttcggt ctattcttca atttcaaaag
    73981 tataaggggc gcattgcatg gaaggggaca gtcctgaaaa agaaaaagag tttgtaccgt
    74041 gatctgacga gtattgttca ggaagctgag aagcagttta tccgagtcag tctgcgagag
    74101 gagcttcaat tagatggacc tgattctgaa agaaatcagc ggatttttca agctttacga
    74161 tattttgatt tggagcaggc agtcgataag agtccctatc aattaagtgg tggtcagcaa
    74221 aaaattcttc agctcctgac catcttgacc agtaaggctt ccgtgatctt gctagatgaa
    74281 ccttttgcag gtttggatga tagagcctgc cattattttt gcaagtggat tgtggaggag
    74341 aggaatcaag gaagaagttt tctgctcatt agtcatcgtt tagacccttt gatttctgtg
    74401 gttgattatt ggattgagat gactagtcag ggtcttcggc atgtgaaaga agtgaccatt
    74461 accaaaccac ttacatctca gagtagcaat acccaagggg aggtgagata gtatggtcaa
    74521 agtagcaacc cagacaccga ttatcagtct cttcttgctg attttatcct tggaaacatc
    74581 tttcattcct tcgattgctc tgaatctttc ggtagtcgca ttttgtattc tctttatgct
    74641 ctattaccgt cgatttaaaa tgttagcttg gatgatcata cttgccattt taccatcttt
    74701 tgccaactac tgggcagttc agttacacgg agatgcttca caggcagtca tgcttggaac
    74761 gagggccttt gtgacagttt gtatcggcct tgtctttgtt tcctctattt cactaaaaga
    74821 gcttctcttg tacttggctc aaaaggggct atcacgctct tggtcctatg ccttgattgt
    74881 ggtattcaat tcctttcctc tcattcagca agaaatcaag tccctcaaag aagcttgtct
    74941 attacgtggt caagaactgc atttttggtc gcccttgatt tacagtaagg ttctgatgac
    75001 agtctttagg tggcgccatc tttacctgag agctctgtct gctcatggat atgacgaaca
    75061 tgcacagttt aagaatagct atcggacttt ttatattcct aaaaaaacaa aattaatcta
    75121 cctgcttttc tttttattgc ttcaaaccag tctattttta taaaggagtt attatggaat
    75181 ttacagatat tgcgatggaa ttatccaaga aagcttggca ggcttccttt catcatccct
    75241 ttattttaca attacaagag gggaatttag aacctgccat tttccgctat tacctgattc
    75301 aggatgccta ctatctgaag gccttctcag aaatctatca tcttttggct gataagactt
    75361 caaaccaaga gatgaaaaga ctcttgaaac aaaatgctca gggtttagtg gagggtgagt
    75421 tatttattcg ccaacaattt ttcaaggaaa tggaaatcag cgaccaggaa atggagcaac
    75481 atccaattgc tccaacctgt tatcattaca tttctcatat ttataggcaa tttgcagaac
    75541 cgaacttagc catcgctttt gcaagcttgc ttccttgtcc ttggttatac catgatatag
    75601 gcaaatcact taatcttaaa ccatcaccaa atcctctcta tcaacaatgg attgaaactt
    75661 atattacgga tgagttagag caacagatca gagaggaggg agcactggtc aatcagctct
    75721 atcgagaaag tgatgagaca gataagcaaa aaatgctaga tgccttccac atcagtgttc
    75781 atatggaagc caagttttgg gagatggctt accaacacca gacatggaag agcgatttac
    75841 agtctttaga aaaaggagaa gaatagaaac atgagaaagc accaactaca agttcacaaa
    75901 ttgaccattt tatctatgat gattgccctt gatgtagtcc ttacacctat ctttcggatt
    75961 gagggaatgg caccgatgtc cagtgtagtc aatattctag cgggaatcat gatgggacct
    76021 gtttatgcct tggctatggc tacagtgaca gcctttatcc gtatgacgac tcaagggatt
    76081 ccgcctttag ctctcacagg agcgactttt ggagcccttc tagcaggtct cttttataag
    76141 tacggtcgaa aattttactt ttctgccttg ggagaaattg tgggaacagg tattattggt
    76201 tctattgttt cctatcctgt tatggtgctc tttacaggat cggctgctaa gcttagttgg
    76261 tttatctaca cgcctcgatt tttcggagca accttgattg gtacagcgat ttcctttatt
    76321 gcatttagat ttttaatcaa gcaggaattc tttaaaaaag tgcaaggata tttctttgct
    76381 gaaaggatag aatgatgcag gcattgacaa atccttttcc tataggctct agttccctca
    76441 ttcactgtat gaccaatgag atttcttgtg agatgctggc aaatgggatt ttggctctgg
    76501 gatgcaaacc tgtcatggca gatgatcccc gtgaagttct tgattttact aagcaaagcc
    76561 aggctctctt catcaatttg gggcatttgt cagctgagaa ggaaaaagca atccgcatgg
    76621 cagctttgta tgcaaaccaa tcttctctcc cgatggtagt agatgcggtt ggcgtaacga
    76681 cttcatccat tcgtaagagc ttagttaaag accttttaga ctatagacct acggtcctta
    76741 aaggaaacat gtcagaaatt cgaagtcttg ttggattaaa gcatcacggc gttggggtcg
    76801 atgcgagtgc taaagatcaa gaaacggagg atttgcttca agtcttgaaa gactggtgtc
    76861 agacctatcc tggtatgtca ttcttagtca caggtcccaa ggaccttatt gtttcggaga
    76921 atcaagttgc tgtacttgag aatggctgta ctgaattaga ctggataaca gggacaggag
    76981 acttggttgg agccttaaca gctgtttttc tcagccaagg aaagactggt tttgaagctt
    77041 cttgcttagc agtctcttat ctcaatatcg ctgctgagaa aatagttgtt caaggaatgg
    77101 gattggaaga atttcgttac caagtactca atcagctttc gctcctaaga agagatgaaa
    77161 attggctaga taccatcaaa ggagaggttt atgaatagag aagcgcttag actatatctg
    77221 gtaaccaatc gctatcaaga ttccgtggaa agctttcttg caaaagttga gacggcctgc
    77281 cgttcagggg ttaccatagt ccaattgcga gaaaaaaatc tcacaaccaa tcaatattat
    77341 caactggcaa aacaagtcaa ggaaataaca gatgcctatc aggtcccctt gataatcgat
    77401 gatcggttgg atgtttgtct tgcggttgat gctgctggtc tgcatattgg agatgacgaa
    77461 ctcccagttt cggttgcccg acaagtcttg ggtcctgaaa aaatcctcgg tgtcaccgct
    77521 aaaacggtta aaagagctct ggaagcggag aaatcaggtg cagattactt ggggacagga
    77581 gccatttttc cgacaaccac caaggaaaat gcacccatca ccctgatttc aaccttgaaa
    77641 acaatttgcc aaacggttgc cattccaata gttgctattg gcggcttgac ttcggagaat
    77701 attgatcagc ttatgggcac tggtatagct ggtgtagctg ttgtacgtga tttgatgcaa
    77761 gcagaagata ttgaggcaaa aacgcaagcc tttttaacaa agttgcatga cattctttcc
    77821 taattaatac tcaatgaaaa tcaaagagta aactagaaag ctagtcgcag gttgctcaaa
    77881 gtactgcctt gaggttttag ataagactga cgaagtcagc tcaaaacagt gttttgaggt
    77941 tgcagatgga agctgacgta gtttgaagag attttcgaag ggtataaaaa ctctctaatt
    78001 cccttaaagt gggaactaga gagttttttt cttaatcttt aaaagttgta tggttgactg
    78061 gaccagaacc atgaccgagt tgaggggcat cttgaatagc ttttgtgata aaggccttgg
    78121 ccttatcaac tgcctggtaa agactcttgc ccttggctag ttcagcagta atcactgcag
    78181 caaaggtaca tccagtacca tgggtgtgac aggtttgaat tcgtgggctt tcccagacaa
    78241 attgttcatt cttggtaaag aggaaatctt tagcaccacc tttgagatgt ccgcctttga
    78301 taaccacaga ctgaggacca aattctttta aaatcaggcg accagcacgc tgcatgtctt
    78361 cggggtcatg gattgaaaaa ccaacaatct cttctgcttc aggaagattt ggcgtaataa
    78421 tagttgctag aggtagtaag tttgttttga gatagtctct agcacttgag tcaatcaagg
    78481 catctccact tgtagcaacc ataacaggat caaggacata gggacaatcc agttttttaa
    78541 gatagggttg gatgatttcc atgatttcag tagtagccaa cattccagtt tttacagcct
    78601 gaggtggaat atcagaaaag acactctcca attgggcttt caacatttga ggagaaacgt
    78661 gctcgattag ctgaacacct ctggtatttt gagcgacaag actggttaca acagccattc
    78721 catagacatc tctcgcttgg aatgacttta aatctgccat aatgccagca ccaccactag
    78781 ggtcagtccc tgcaatggtt aaagcaacgg gtaaataagt catctaaaac ctcccaacca
    78841 actgaagttt gtattcttaa gaacaagcta gtctgtttta gaaaggcaat agaagactgc
    78901 tagtccccat tatcatttcc acttccatca gctagcatta cctagattga gtcagaggga
    78961 tctaacagtc gttaatctca gctttacgca cccctagtgg ttgttttctt ttttctttag
    79021 tatagcatat ttttattgtt tatatagtaa tatttgactg caaatcgttt ttcaaatgat
    79081 taaaattcta tttttcgaag aaaa
//
LOCUS       DAVKMO010000004        67933 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVKMO010000004 DAVKMO010000000
VERSION     DAVKMO010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67933
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.004"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(28..228)
                     /locus_tag="VW361_000283"
     CDS             complement(28..228)
                     /locus_tag="VW361_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9743418.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(231..1238)
                     /locus_tag="VW361_000284"
     CDS             complement(231..1238)
                     /locus_tag="VW361_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9743419.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTMKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            1429..3459
                     /locus_tag="VW361_000285"
     CDS             1429..3459
                     /locus_tag="VW361_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU9743420.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKVSSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYNDIKMIIKQED"
     gene            3463..3747
                     /locus_tag="VW361_000286"
     CDS             3463..3747
                     /locus_tag="VW361_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9743421.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKICEEKGLI"
     gene            3760..5106
                     /locus_tag="VW361_000287"
     CDS             3760..5106
                     /locus_tag="VW361_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9743422.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            5110..5967
                     /locus_tag="VW361_000288"
     CDS             5110..5967
                     /locus_tag="VW361_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9743423.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            5964..6896
                     /locus_tag="VW361_000289"
     CDS             5964..6896
                     /locus_tag="VW361_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU9743424.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            7129..8832
                     /gene="ilvD"
                     /locus_tag="VW361_000290"
     CDS             7129..8832
                     /gene="ilvD"
                     /locus_tag="VW361_000290"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU9743425.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(8948..9028)
                     /locus_tag="VW361_000291"
                     /pseudo
     CDS             complement(8948..9028)
                     /locus_tag="VW361_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(9086..9427)
                     /locus_tag="VW361_000292"
     CDS             complement(9086..9427)
                     /locus_tag="VW361_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9743426.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            9551..10402
                     /gene="rgg"
                     /locus_tag="VW361_000293"
     CDS             9551..10402
                     /gene="rgg"
                     /locus_tag="VW361_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU9743427.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIMIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSAFLSVSLFTRYVREMVRKSDFLMEMSGNRNFFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            10595..11842
                     /locus_tag="VW361_000294"
     CDS             10595..11842
                     /locus_tag="VW361_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU9743428.1"
                     /translation="MKLLFRNPAYRILTLSCFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMLLPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            11920..13209
                     /locus_tag="VW361_000295"
     CDS             11920..13209
                     /locus_tag="VW361_000295"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU9743429.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVSQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            13206..13283
                     /locus_tag="VW361_000296"
                     /pseudo
     CDS             13206..13283
                     /locus_tag="VW361_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            13550..13864
                     /locus_tag="VW361_000297"
     CDS             13550..13864
                     /locus_tag="VW361_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743430.1"
                     /translation="MWVLVFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDKKGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            13874..14080
                     /locus_tag="VW361_000298"
     CDS             13874..14080
                     /locus_tag="VW361_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9743431.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            14080..14277
                     /locus_tag="VW361_000299"
     CDS             14080..14277
                     /locus_tag="VW361_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743432.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            14280..15014
                     /locus_tag="VW361_000300"
     CDS             14280..15014
                     /locus_tag="VW361_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU9743433.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            15026..15667
                     /locus_tag="VW361_000301"
     CDS             15026..15667
                     /locus_tag="VW361_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9743434.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            15685..15915
                     /locus_tag="VW361_000302"
     CDS             15685..15915
                     /locus_tag="VW361_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743435.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            15951..16031
                     /locus_tag="VW361_000303"
                     /pseudo
     CDS             15951..16031
                     /locus_tag="VW361_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            16267..18030
                     /gene="aspS"
                     /locus_tag="VW361_000304"
     CDS             16267..18030
                     /gene="aspS"
                     /locus_tag="VW361_000304"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU9743436.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPHMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEALAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            18008..18949
                     /locus_tag="VW361_000305"
     CDS             18008..18949
                     /locus_tag="VW361_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9743437.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(19069..19149)
                     /locus_tag="VW361_000306"
                     /pseudo
     CDS             complement(19069..19149)
                     /locus_tag="VW361_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(19285..20271)
                     /locus_tag="VW361_000307"
     CDS             complement(19285..20271)
                     /locus_tag="VW361_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9743438.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(20281..21081)
                     /locus_tag="VW361_000308"
     CDS             complement(20281..21081)
                     /locus_tag="VW361_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU9743439.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PGQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(21342..22184)
                     /locus_tag="VW361_000309"
     CDS             complement(21342..22184)
                     /locus_tag="VW361_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9743440.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(22186..23478)
                     /locus_tag="VW361_000310"
     CDS             complement(22186..23478)
                     /locus_tag="VW361_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9743441.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLSVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(23589..24860)
                     /locus_tag="VW361_000311"
     CDS             complement(23589..24860)
                     /locus_tag="VW361_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9743442.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            25410..26927
                     /gene="malQ"
                     /locus_tag="VW361_000312"
     CDS             25410..26927
                     /gene="malQ"
                     /locus_tag="VW361_000312"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU9743443.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEDL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            26953..29211
                     /gene="glgP"
                     /locus_tag="VW361_000313"
     CDS             26953..29211
                     /gene="glgP"
                     /locus_tag="VW361_000313"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU9743444.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(30255..30827)
                     /locus_tag="VW361_000314"
     CDS             complement(30255..30827)
                     /locus_tag="VW361_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743445.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLVSWFVNDVALE
                     FAMNLLSSGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(31626..32474)
                     /locus_tag="VW361_000315"
     CDS             complement(31626..32474)
                     /locus_tag="VW361_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9743446.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDDN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSKLTEITIEAEI
                     LVGKAF"
     gene            32626..32904
                     /locus_tag="VW361_000316"
     CDS             32626..32904
                     /locus_tag="VW361_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743447.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            32906..34969
                     /locus_tag="VW361_000317"
     CDS             32906..34969
                     /locus_tag="VW361_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9743448.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRICVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(35047..36303)
                     /locus_tag="VW361_000318"
     CDS             complement(35047..36303)
                     /locus_tag="VW361_000318"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU9743449.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            36445..38910
                     /locus_tag="VW361_000319"
     CDS             36445..38910
                     /locus_tag="VW361_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9743450.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKAGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            38975..39886
                     /locus_tag="VW361_000320"
     CDS             38975..39886
                     /locus_tag="VW361_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU9743451.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            40116..40814
                     /gene="dapD"
                     /locus_tag="VW361_000321"
     CDS             40116..40814
                     /gene="dapD"
                     /locus_tag="VW361_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU9743452.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            40882..42012
                     /locus_tag="VW361_000322"
     CDS             40882..42012
                     /locus_tag="VW361_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU9743453.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPDQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEAVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            42024..42563
                     /locus_tag="VW361_000323"
     CDS             42024..42563
                     /locus_tag="VW361_000323"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU9743454.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKRVLTPKTYPKGRMDFVVYDPQQLVKTSFGLLEPQ
                     GDLEVVDVSKIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            42547..43224
                     /locus_tag="VW361_000324"
     CDS             42547..43224
                     /locus_tag="VW361_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU9743455.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(43291..44190)
                     /gene="galU"
                     /locus_tag="VW361_000325"
     CDS             complement(43291..44190)
                     /gene="galU"
                     /locus_tag="VW361_000325"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU9743456.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMNDYEKTHAST
                     IAVMPVPHEDVSSYGVIAPQGEGSNGLYSVETFVEKPAPEETPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFTGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(44212..45228)
                     /locus_tag="VW361_000326"
     CDS             complement(44212..45228)
                     /locus_tag="VW361_000326"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9743457.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKNVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRSAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            45440..45821
                     /locus_tag="VW361_000327"
                     /pseudo
     CDS             45440..45821
                     /locus_tag="VW361_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(45994..46419)
                     /locus_tag="VW361_000328"
     CDS             complement(45994..46419)
                     /locus_tag="VW361_000328"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9743458.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEIRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(46487..47137)
                     /gene="phoU"
                     /locus_tag="VW361_000329"
     CDS             complement(46487..47137)
                     /gene="phoU"
                     /locus_tag="VW361_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9743459.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAKL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPGEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(47152..47904)
                     /gene="pstB"
                     /locus_tag="VW361_000330"
     CDS             complement(47152..47904)
                     /gene="pstB"
                     /locus_tag="VW361_000330"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9743460.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(47906..48721)
                     /gene="pstA"
                     /locus_tag="VW361_000331"
     CDS             complement(47906..48721)
                     /gene="pstA"
                     /locus_tag="VW361_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9743461.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(48714..49577)
                     /gene="pstC"
                     /locus_tag="VW361_000332"
     CDS             complement(48714..49577)
                     /gene="pstC"
                     /locus_tag="VW361_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9743462.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYSFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(49695..50570)
                     /locus_tag="VW361_000333"
     CDS             complement(49695..50570)
                     /locus_tag="VW361_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEU9743463.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(50737..52068)
                     /locus_tag="VW361_000334"
     CDS             complement(50737..52068)
                     /locus_tag="VW361_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU9743464.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAKYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(52069..52776)
                     /locus_tag="VW361_000335"
     CDS             complement(52069..52776)
                     /locus_tag="VW361_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9743465.1"
                     /translation="MTKQVLLVDDEEHILRLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGIKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(52860..53345)
                     /locus_tag="VW361_000336"
     CDS             complement(52860..53345)
                     /locus_tag="VW361_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU9743466.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERADLLATYPEHKEMIEHLTR
                     Y"
     gene            53331..53888
                     /locus_tag="VW361_000337"
                     /pseudo
     CDS             53331..53888
                     /locus_tag="VW361_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(54278..55969)
                     /locus_tag="VW361_000338"
     CDS             complement(54278..55969)
                     /locus_tag="VW361_000338"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU9743467.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            56105..56551
                     /gene="argR"
                     /locus_tag="VW361_000339"
     CDS             56105..56551
                     /gene="argR"
                     /locus_tag="VW361_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9743468.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            56602..59136
                     /gene="mutS"
                     /locus_tag="VW361_000340"
     CDS             56602..59136
                     /gene="mutS"
                     /locus_tag="VW361_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU9743469.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREESA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQYLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            59283..60977
                     /gene="patA"
                     /locus_tag="VW361_000341"
     CDS             59283..60977
                     /gene="patA"
                     /locus_tag="VW361_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU9743470.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SNELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQDGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(61295..61558)
                     /locus_tag="VW361_000342"
                     /pseudo
     CDS             complement(61295..61558)
                     /locus_tag="VW361_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            61752..63518
                     /gene="patB"
                     /locus_tag="VW361_000343"
     CDS             61752..63518
                     /gene="patB"
                     /locus_tag="VW361_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU9743471.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            63657..64346
                     /locus_tag="VW361_000344"
     CDS             63657..64346
                     /locus_tag="VW361_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9743472.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            64350..64529
                     /locus_tag="VW361_000345"
     CDS             64350..64529
                     /locus_tag="VW361_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743473.1"
                     /translation="MQHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTRKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            64516..65865
                     /locus_tag="VW361_000346"
     CDS             64516..65865
                     /locus_tag="VW361_000346"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU9743474.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDKKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            65989..67449
                     /locus_tag="VW361_000347"
     CDS             65989..67449
                     /locus_tag="VW361_000347"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU9743475.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENILKEISK"
     gene            67463..67897
                     /locus_tag="VW361_000348"
     CDS             67463..67897
                     /locus_tag="VW361_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9743476.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGKERASKFNER"
BASE COUNT        19954 a        12625 c        14718 g        20636 t
ORIGIN      
        1 atccgacacg gcagacagga gaaggtgtta aatatcaatc tcaaatggtt cgtcaatggt
       61 ttctgatacg tattttccgt cttttttccg ttgcttgaca cactctgtga ggagatattc
      121 gatttgccca ttgactgaac gaaagtcgtc ttctgcccat gatgcgagtg cagcgtataa
      181 ctttgttgag agtcgaaggg ggatctgctt ttttttagct tcagccatct ttagtaaaga
      241 cttcctgtgt tgacaattgg ttgtgcatca tgattgccac aaagaacgac aaggagattt
      301 gaaaccatgg cagcttttcg ttcttcgtca agttctacca attccccttc attgagccgt
      361 tctagtgcca tttcaaccat tcctacagca ccatctacaa tcatcttccg tgcatcaata
      421 atggcagatg cttgttggcg ttgaagcata acggcagcaa tttctggagc ataagctagg
      481 taagtgatac gtgcttcaag gatttccaag ccagcatctt ctacgcgact ttgaatttcc
      541 tcacgaatac ggttagcaac aatttcgcta gagccacgga gactaccttc atctgcttgc
      601 ccgtcacccg tagtatccac attaggagac acatcgtaag gatagatgcg gacaatatta
      661 cggagggcgc tatcacattg caatgaaaga tattctttgt agttatcaac gttgaagact
      721 gccttagcgg tatcgacaac tctccaagtt accgcgatac cgatttctac agggtttcct
      781 aagcaatcat tgattttttg acgagaattg ctcaaggtca tgactttgag ggaaatgtgt
      841 ttcttgccaa tttcaagatt tacatcattg tcatttgatg atttagctcc taaaaaagga
      901 gattttgtgc taacatcacc actttgtcca agtcgagtgt ggtttgcagg gttgactgct
      961 acgctgaagg gattgacaaa gtaaaaacca ggttctttca tggtacctgt ataattacca
     1021 aagagtgtca gaaccagagc ttcctgaggt ttgacaactt ttaaaccagc atgagctaga
     1081 cctgcaatta cgattagtaa aggtccgata ataattccaa aaatgttttc cgaaccaaca
     1141 cccattataa atataaagat accaagtacg attgtcaact caatgagaat caatgcgaat
     1201 acaccatttg gttttgaatt gattagtttt tcagtcataa gaatgacctc ccattatttg
     1261 atatctaaat gatatcactt tgtttttaaa agtcaataga aagttgaaaa taatcactaa
     1321 aaactttcag cccaataatt tcttttaaaa ggtgagatta tattgtgctc aaatactctt
     1381 ttattcttat aatttttaca ctataattgt agttagaaag gaagagaaat gtttgattat
     1441 agagcactag ttattttgat gactttgatg gatcattgtg agctatcatt atatgaatta
     1501 tctgttaagg tgagcttacc tataaaggaa gtcaaagaag gaatagatta tttagtgcct
     1561 tatctagcta ataaagggat agtgctggat aaaaaacaag gtcgctatag tttatcaaat
     1621 cgtacgaagc agtctttgac agatattatt aagtcggatg aattggtttt accaaagtcg
     1681 actcgcttag ctttaatcta tctttacact ttttgccgat tagattttat atcgaataat
     1741 cattaccaag actttttgaa agtaagtaag aatacaacct tatctgatat tcaatcatta
     1801 agaaagatta tgttagataa tgatttggag ctagggtaca gtagagcaaa aggttatact
     1861 ttacacggtt cagagtggaa taagcaccgc ttagcttttc aaatggttag tgagttgctg
     1921 gaatcctcca tagggatttg gggtttggat tatgttttat ccagttgggg gtattcatta
     1981 acttatgatt tgataaatca ggtagttaaa gattattatg agaagctaca gctagtacct
     2041 attgttaatc aattaaaagt ttaccttttc ggtttagtat tcattctgtg taggtatcaa
     2101 agggatgttg aaagagtatg tctttcagag acattagtat ctcctgttat tcaagatata
     2161 accactattt tattggatac agtggttgat ttgggaatta tagatacggt gttttctgag
     2221 gatgattatc gctatatcac agttttatta tcaagttgct ttgaaggtga agtagatgtt
     2281 gctccggttt actttaatca attaacagag gctattataa gtagaatgga agatatttct
     2341 ttgttacatt ttaaacaaag ggaaggattg agagaaaatc ttcgccgcca ccttataccg
     2401 gcttactata gattaaagtt cggcctacct agttcaaatg aatatgtatt gcatgttaaa
     2461 gaacattatc ctgatttatt tgaattagtc aaagattctt tgatgccctt gatggacgct
     2521 attgacaatc ccatacctga tagtgaaaca gcatattttg ttatccattt cggaggttat
     2581 ttaaagaaag cagatacttt gcctcaaaaa tgctataaag cagcaatcat ttgtcctaat
     2641 ggtgttagtt cttcattgat gttaaaagag aatctattag cattatttcc tcaaattgag
     2701 tttataggaa cctcaaagat tgatgattta caggtgaaag ttagtagtga ctatgatatg
     2761 gttttttcta ccataaaggt ggagacagaa aagccaaatt atctagtttc ggttatgatg
     2821 actgaagagc aagcaataca actagtagaa ctagtgttaa aagattttcc gaatttagag
     2881 tatggagatt ttgagattga acaaatcctg aatattgtca aaagatatgg aattattaca
     2941 caagaattgg aattaagatt ggcgttaaag aattatcttt atcaaaaaaa tgatagaaag
     3001 gaaattgtac cagtgctaga acaacttatt accaaagaaa cctatcaggt tagttcgcaa
     3061 aaattaggat ggaaggaggc gattcgttta gcagctaaac cgcttttgga tcaagataag
     3121 ataactgaga actaccctga ggcaatgatt caaaaagtag aagagtttgg accttttatt
     3181 aatttaggga agggagtagc aattcctcac gctcggccag atgaaggtgt gaatgaaata
     3241 ggaatgtcaa tgttagtttt ggaagaaccg atttatttat tggataatcc agaacaagag
     3301 gtaagattgt tgatttgtat tgcagccatt gataatgaga gtcatttaaa ggctttgtca
     3361 catttaacaa caattttaag agataaaaat catgttcaaa ctttaatatc atcaaaaaac
     3421 tataatgata ttaaaatgat aattaaacag gaggattaga taatgttaaa aattggtaca
     3481 gcttgtggtt caggattagg ttcaagtttt atggtacaga tgaatattga atctgtattg
     3541 agtgatttga atgtttcgga tgtagaagtt gaacattatg atttaggtgg agcagatcca
     3601 aatgcagctg atatttggat tgttggtcgt gatctagctg attcagctag tcatcttgga
     3661 gatgttcgta tcttaaatag tattattgat atggacgaac tacgagaatt aattactaaa
     3721 atttgtgaag aaaaaggact tatataggag gctagcgtca tgatgaagtt catattggat
     3781 attgttagta caccagctat tttagtagct ttaattgcaa tcttaggatt agttcttcag
     3841 aagaagaaat tacctgatat tattaaaggt ggaattaaga cctttgttgg tttcttagtt
     3901 gtatctggtg gtgcaggaat tgtacaaaat tctttaaatc catttggtac catgtttgag
     3961 catgcttttc atttatctgg cgttgtgccg aataatgaag caattgtagc tgtagcttta
     4021 acaacatatg gctcagctac tgcaatgatt atgtttgcag gcatggtgtt caatatctta
     4081 atcgctcgtt ttactcgatt taaatatatt tttttaacag ggcaccacac tctatatatg
     4141 gcatgtatga ttgcggtcat tttatcagtt gctggcttta ctagcttgcc tctcatctta
     4201 ctaggaggat tagcactcgg tattattatg agtatttccc cagcatttgt tcaaaaatat
     4261 atggttcaat taactggaaa tgacaaggtg gctttaggtc atttcagttc tttgggatat
     4321 tggttgagtg gttttactgg tagccttatc ggtgacaaat caaaatcaac agaggacatt
     4381 aaatttccaa agagtttagc ttttttacgt gatagtactg ttagtattac tttatccatg
     4441 gcagttattt acattattgt agctatcttt gcagggtcag aatatataga aaaagaaatc
     4501 agtagtggta caagtggtct agtttatgct ttacaattag caggtcaatt tgcagcaggg
     4561 gtatttgtta ttttagcagg tgttcgcctt attttgggcg aaattgttcc agcctttaaa
     4621 ggtatttcag agcgtcttgt acctaattcc aaacctgctt tggattgtcc gattgtttat
     4681 acttatgcac ccaatgcagt tctaattgga tttatctcta gttttgttgg tggtttagta
     4741 agtatggtaa ttatgattgc ttcaggaacg gttgttatct taccaggcgt tgtacctcat
     4801 ttcttctgtg gagcgactgc aggtgtcatt gggaatgcat ctggtggtgt tcgtggagcc
     4861 actattggag catttttaca aggtatttta atcagttttc ttccagtctt tttaatgcca
     4921 gttttgggag gacttggttt ccaaggatca actttctcag atgcagattt tggtctatca
     4981 ggaattattt taggaatgtt aaatcaattt ggttcacaag caggcattgt gattggtctt
     5041 gttcttattc tagcagttat gtttggagta tcctttatta aaaagccatc tgcaaaggag
     5101 gaataaggga tgattttaag taaaaataga gaagatgggt taagaaaatt tgcgactaac
     5161 atccgattaa atactcttag aacattgaat catcttggat tcggacatta cggaggaagt
     5221 ctgtctatcg tagaagtttt agcagtgctt tatggtgaaa taatgccaat gactccagaa
     5281 atatttgcag cacgagatag agattatttc atattatcaa aaggtcatgg aggaccagct
     5341 ctatacagta cactctattt gaatggtttc tttgacaaag aattcctata ttctttaaat
     5401 acaaatggaa ccaaattacc gtctcatcct gatagaaatc taacgccagg catagatatg
     5461 acaacgggct ctttaggaca aggaattagt gttgcaactg gacttgcata tggtcagaga
     5521 ataagaaaga gtccctttta tacttatgct attgttggag atggtgagtt aaatgaggga
     5581 caatgttggg aggctataca gtttgcttct catcaacagt tatccaactt aattgtattt
     5641 gttgatgata acaaaaaaca attagatggt tttacaaagg atatttgtaa tccaggtgat
     5701 ttcgtagaaa aattttcagc atttggattt gaatccatta gggtcaaggg ttcagatatt
     5761 agagaaattt atgaagggat tgtccaatta aaacagtcaa ataattcatc acctaagtgc
     5821 attgtattag atactattaa aggtcaaggg gttcaagagc tggaagaaat gaaatccaac
     5881 catcatcttc gccctactgt agaggagaga caaatgttaa cttcagttgt agaaagatta
     5941 agtcaggaat tggaggaaac agaatgatga gaagcacgaa agaattacgg catgtatata
     6001 gagacttcct tttagaggct aatcaaagtt attctgatat agtagtctta gaagccgatt
     6061 tgtcaagttc gatggctact aataatcttg aaaaggactt tggagaccgt tatgtgaatg
     6121 ttgggattat ggaagcagaa atggtcggcc ttgcagcagg cttgtctatt caggggttta
     6181 gaccttatct tcatacattt ggtccttttg cttcacgaag agtatttgat caattattta
     6241 tttctcttgg atacgcacaa ttggatgcca ctgtgattgg atcagatgca ggagtaactg
     6301 cagaaatgaa tggtgggaca catatgccat ttgaagaaat tggattgtta cgtttaattc
     6361 ctaaatcgat catttttgaa gcaactgatg atatccaatt tcgtgaaata ttgaaccaga
     6421 cattagactt aaaaggacta aaatatattc gaacaattag aaaagctcca gttcctgtgt
     6481 atcaaggtgg agaagatttt tctaaaggct acattgagtt aaggcatggt gaagatcttg
     6541 taatcgttgc ttctggtata atggttgctc caagtattcg agttgcagat gaactgtcta
     6601 aattaggtta ttcagtaggt gtgatagatt tatttagaat caaaccgata ccagaacaga
     6661 taaaaacaat gttaagtgga aaaactatat ttactgtaga aaaccacaat cagataggtg
     6721 gaattggcag tgctttatgt gaattattct ctgatgatgg aataacaaaa attcatcgga
     6781 tgggtgttca agaaagattt ggtcaagtag ggaaaatgga ttatcttctt aatgagtatg
     6841 gtttgagtga atcgaatata aaagagaagg ttctagaaat ttataatgca agatagatgt
     6901 taaatacact tatctgaaag aatttctgta aaaattacat tacgttattt aaagaaagcg
     6961 gattaaaaag catattctgg tcatcagaaa gtgcactaat ccgctttgtt gtttttaatt
     7021 ttaaatattt cacatgcgta tagaattttc tgaaaattca agaattttat tctgttcatt
     7081 gcctttaaat tgtgctataa tagtaaaaac tgaaatggga tggataagat gactgaatta
     7141 gataaacgtc accgcagtag catctatgac agcatggtta aatcacctaa ccgtgctatg
     7201 cttcgtgcga ctggtatgac agataaggac tttgaaacat cgattgtggg agtgatttcg
     7261 acttgggcgg aaaatacacc atgtaacatt cacttgcatg atttcgggaa actggctaaa
     7321 gaaggtgtca aatctgcagg cgcttggcct gtacagtttg gaaccattac cgtagcggac
     7381 gggatcgcta tgggaacgcc tggtatgcgt ttctctctaa catctcgtga catcatcgcg
     7441 gactccatcg aggcggctat gagtggtcac aacgtggatg ccttcgtcgc tatcggtggc
     7501 tgtgacaaga acatgcctgg atctatgatt gctattgcta atatggatat cccagctatt
     7561 ttcgcctatg gtggaactat tgcaccggga aatcttgatg gtaaagatat cgacttggtt
     7621 tctgtctttg aaggtatcgg aaaatggaac cacggtgaca tgacagctga ggacgtgaaa
     7681 cgtcttgaat gtaatgcctg ccctggccct ggtggttgtg gtggtatgta tactgctaat
     7741 accatggcaa ctgctatcga agttctaggg atgagtttgc cagggtcatc ctctcaccca
     7801 gctgaatcag ctgataagaa agaagatatc gaagcagcag gacgtgctgt tgttaagatg
     7861 ttggaacttg gtctcaaacc atcagatatc ttgactcgtg aagcctttga agatgctatt
     7921 actgtaacga tggctctcgg tggttctaca aacgccactc ttcacttgct cgccattgcc
     7981 catgccgcaa atgttgactt gtcacttgag gacttcaata cgattcaaga acgtgtgcct
     8041 cacttggccg acttgaaacc atctggtcag tatgtcttcc aagacctcta cgaagtcggt
     8101 ggtgtccctg cggttatgaa gtacttgttg gcaaatggtt tccttcacgg agatcgcatc
     8161 acatgtactg gtaagactgt agctgaaaac ttggctgact ttgcagactt gactccaggc
     8221 caaaaagtta tcatgccact tgaaaatcca aaacgtgcgg atggtccgct tatcatcttg
     8281 aacgggaacc ttgctcctga cggtgcagtt gccaaggtat caggtgttaa agtgcgtcgt
     8341 cacgttgggc cagctaaggt ctttgactca gaagaagatg cgattcaggc cgttctgaca
     8401 gatgaaatcg ttgatggcga tgtagtcgtt gttcgttttg ttggacctaa aggtggtcct
     8461 ggtatgcctg agatgctgtc actttcatca atgattgttg gtaaaggtca gggagataag
     8521 gtggccctct tgacggacgg acgtttctct ggtggtactt atggtctggt tgttggacat
     8581 atcgctcctg aagctcagga tggtggacca attgcctatc tccgtaccgg cgatatcgtt
     8641 acggttgacc aagataccaa agaaatttcc atggccgtat ccgaagaaga acttgaaaaa
     8701 cgcaaggcag aaacaacctt gccaccactt tacagccgtg gtgtcctagg taaatatgcc
     8761 cacatcgtat catctgcttc acgcggagcc gtgacagact tctggaatat ggacaagtca
     8821 ggtaaaaaat aaactcatac tcgaaaatct cttcaaatca cgtcaacgtc gccttgccgt
     8881 aggtatggtt actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga
     8941 cttcgtcagt tctatccata acttcaaaac agtgttttga gcaacctgcg gctagttttc
     9001 tagtttgccc tttgattttc attgagtatc aaaaagcaag ccattttcgg cttgcttttt
     9061 tcatctttaa aagtgattgg cctgcttaac gaggtggtag tccaagggca atacggccat
     9121 agcgactgat tcgtgtgatt ttccaggcag gcgaccaggt aacttcaacc ttgatatctt
     9181 tgataccctc gatttgtttc agacctgcca cgatttcaat aggcaggctt tcggcgcaat
     9241 cacaggcagt atcggtgaag gtcatgacaa tcttgcagag ccccgtttca tccagattga
     9301 tttcataaat cagacctaga ttgtaaacat ccaattccac atctgtatca aaaactttct
     9361 ctagtttttc gataatttgg tcttgcaagg ccaaagcacg gtcattgatt ttgatatcgt
     9421 ctctcatagc agtccctcca cgtgataaat atcctctatt ttctcataat tctgacaatt
     9481 tggcaagttt ttgatgaatt ttctgaaaaa tatgataaaa tgaagaaaat acggaatcaa
     9541 ggggaagtct atggagcaga ttggaaaagt ctttagacaa ttacgagaat caagaaatat
     9601 ctcactgaga caagcaaccg gaggacaatt ttcgccgtct atgttgtccc gttttgaaac
     9661 aggtcagagt gagctttcgg tggaaaagtt tctatttgct ctggaaaata tatctgccag
     9721 tgtggaggag atcctctttc tggcgagagg tttccagtat gatacagatt ctgagttgag
     9781 aaaagaaatt acagatgtct tggaaccaaa gaatatagca cctcttgagg acttatatcg
     9841 cagggagtat caaaagcatg cccattctca caacaaacag aaacatattc taaatgccat
     9901 tatgatcaag tcttatatga agagcatgga tgaaagggta gagttaacag cagaggaagg
     9961 aaaagtcctt catgattatt tgttttctac cgagatctgg ggaatctatg aactcaattt
    10021 attttcagtc agttctgcct ttttatctgt ttctcttttt actagatatg tacgagaaat
    10081 ggtacgtaaa tctgattttc taatggaaat gtctggtaat cgaaactttt ttcatactat
    10141 actattgaat ggctttttag ctagtattga gtgtgaagaa tttaccaatg cctattattt
    10201 taaacgtgtt atcgaagagc atttctacaa ggaaaatgag acctatttcc gaattgttta
    10261 tctgtgggca gaaggtctcc ttgatagcaa gcaaggtaga gtcaaggaag gccagaaaaa
    10321 gatggaggat gctgtccgta tttttgagat gcttggctgt aataaatctg ccgaatacta
    10381 tagaaatacg accgaatgtt gaatatctgc aaaccaagaa aaaatttgaa gcgatagaac
    10441 tattgccctc tctcaggtca ttacaaaagt tctatcgttt ctttttgctc attttatttg
    10501 ttgcatatat tcaagagttc tccctctcaa atttctaagt gctatactat agtcatactt
    10561 catatagagg ttcgaacaag aagggagatt atctatgaaa ctattgttta gaaatccagc
    10621 ttatagaatt ttgactttat catgcttctt caatgctttt ggtgcttcga ttttcaacct
    10681 ggtctttatc gtctatgcat cgaccttgtc acaagcatct tttgctgttg ctatggcgaa
    10741 tattgtcatg cttcttccga ccctctttac agtttttgta gggattcggg cagattacac
    10801 gagggacaag gtcaaatgga tggtctatag cggtttgttt caggcggttc tattttttct
    10861 agcagcccta gttgttcagc aagctagtct ctttgccttt tctagcctgt gtttgatcaa
    10921 tgtcattagt gatatcatca gtgattttgc aggtggcctg cgtatgcctc ttattaagga
    10981 aaaagtagct gaagatgatc tgatggaggc ttattctttt tcacagttca tcacctatat
    11041 ttcagctatt ggtggtcaag ctttcggagt ctggctctta gctctatcgg tcaacaattt
    11101 ttctctcgtt gcgggaatca atgcctgctt tttcctagta tcagccacta tcctcttttt
    11161 aggaaaaagc aaattgagcc tgtcaatgtc atctgctgat ggtgaaaact taaaaaatga
    11221 gaagctttct atcaaagacc agttcctaac aatttaccga aatttacgtc tcgtttttct
    11281 taaaagtgga cagaaaaact ttggttttat gctctttgct gtcttgctta ttaattcctt
    11341 gggtggcgct ttgggtggaa tttataatat cttctttttg agccattctc tcttgaattt
    11401 ttcttataca gaggcactat ttatcaatca attctgtgtt ttagtagcag tcatcatcag
    11461 tagccttacg ggcaatgatt attttgggaa gcagtccttg cctagattga tgatgtgggc
    11521 gaccgtagga cttagtctag ttggtttggc taatttattc aatcaagtcg tgcttggttt
    11581 gctatttctc ttctttaccc tgtatgtgtc tggtaaagtt caaccaaaga ttagtgccat
    11641 gctcatgaaa aatctagctc cagaggttct agctcgtact agtaattttt taggtctatt
    11701 gtttacctta tccatacctg tgggaacagc ttgtttttca ctagtagccg tatggaatat
    11761 acagttgact tggatgctat ttgttggtct ttccttgcta gctatttttt tgacaattct
    11821 taatctcaaa aatgatatct aaatcctaat ttttttctta ctgttttaat ccctttattt
    11881 gtggtaaaat aagactatta agtttaaaga ggattcccta tgaaattaca aaaaccaaaa
    11941 ggaacgcagg atattttacc tgctgaatct gctaagtggc agtacgttga gggctttgcc
    12001 cgtgagattt tcaagcgcta taactatgca gaagtgcgca cgcctatttt tgagcattac
    12061 gaggttatca gtcgctctgt cggagataca acggatatcg taaccaagga aatgtacgat
    12121 ttttatgaca agggtgaccg tcatattacc ctccgtccag aaggaactgc gcccgttgtc
    12181 cgttcctatg tggaaaataa actcttcgcc ccagaagtgc aaaagccaag caagttctac
    12241 tacatgggac ctatgttccg ttatgagcgt ccacaggcag ggcgcttgcg ccaattccac
    12301 cagattggtg ttgagtgttt tggttctagc aatccagcta ccgatgtgga aacaatcgtt
    12361 atggcagccc attttttgaa ggaaatcggt attcaaggtg tcaaattgca cctcaacact
    12421 cttggaaatc ctgagagccg tgcagcctac cgccaagcct tgattgacta tttgacaccg
    12481 ctcaaggaga ccttgtctaa ggatagccaa cgtcgcttgg aggaaaatcc tcttcgtgtc
    12541 ttggactcta aggaaaaaga agacaaggtg gcagtagaga atgcgccgtc tatcttggac
    12601 tttcttgatg aagaaagcca aactcatttt gatgctgtga gtcagatgtt ggaaaatctt
    12661 ggagtagatt acatcatcga taccaatatg gtgcgtggtc tggactacta caaccacacc
    12721 attttcgagt ttatcacaga gattgagggc aatgacttga cagtctgtgc gggtggtcgc
    12781 tacgatggtt tggttgctta ctttggaggc cctgaaactg ctggatttgg ttttgggctt
    12841 ggtgtagagc gcctgcttct catccttgaa aaacaaggcg tggccctccc tatcgaaaat
    12901 gccctagatg tctatatcgc agtcttgggt gatggagcaa atgtcaaagc cctagaacta
    12961 gtccaagccc ttcgccaaca aggtttcaaa gcagagcgtg attacctcaa ccgtaaactc
    13021 aaagctcaat tcaagtcagc cgatgtcttt gcagctaaga ccctcatcac cctaggagag
    13081 agcgaagtcg aaagcagaca agtgacagtc aagaacaacc aaacccgaga agaagtgcaa
    13141 gtgtcacttg agacaatcag ccaaaacttc tcagaaatct ttgaaaaact aggattttat
    13201 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacactgtt
    13261 ttgaggttgt ggatagaact gacgaagtca gctcaaaaca tggttttgag gttgtagatg
    13321 aaactgacga agtcagtaac catacctacg gcaaggtgaa gctgacgtgg tttgaagaga
    13381 ttttagaaga gtattaatga tagataaagt ggtcaggaac ttactcctga cctttttctt
    13441 ttgcaaaatg acaaaaatca taaacttttt gacaaatata tttatcaaaa agaaaaagat
    13501 gtgttacaat gaattcaagt taagaaatag gaagcagaaa ggagttataa tgtgggtact
    13561 agtatttata ctatttatga ttttctttta ttctaataat tctaaaaaaa tcaagaaact
    13621 agagaataaa atcaaaaaac ttgagcgaaa agagaaagga aacgcagaaa tgtcgagatt
    13681 attacaagaa atgattggaa aggaaccaat tataacggga gtgtatattg ggccagataa
    13741 ctgggaagtt gtggatgttg atgaggaatg ggtcaaacta cgtagtgttg ataaaaaggg
    13801 gaaagaaaaa ttcaagttgc aacgtattga agatatccaa accgttgaat ttgacggaga
    13861 gtaggtgtgt aacatgcaac taaaaaatcg tctaaaagag cttcgagctc gcgatggtct
    13921 caatcaaacc gacctagcca aactggcagg ggtttccaga cagaccatta gcctactaga
    13981 acgggatgag tacaccccat ccattatcat tgccctgaaa atatctcaaa ttttcaacga
    14041 aacagtcgaa tcggtatttc gtttggagga ggacgagtga tgaacaagta taaagtgatt
    14101 tattatgtag tggtcatagc tttattagtc agtgtatttc tactgattgg gatggaccta
    14161 agctggttta atccctatca aagcgaccaa tttgtttggg tctactttgc tctcatccca
    14221 gtaattgaat ggattgaaaa gaaatccaaa aatctagcaa gtgaaaaagg agaatgaata
    14281 tgaaaaagaa acgtagattg ttatttttga tgtctattgt cttggggggg ttcttgggca
    14341 tgtttgtagg gatgtttaag gcacgtgtcg aatcccacga aattatttta gatgtaaaag
    14401 ccttgatgcc atggatatca gctatttgtt tactgatagg tttcattagt atgtttttga
    14461 ctttcaattt cttaaagaaa agcagaaaat ttcattcctt gtatcaagag gaaatggatg
    14521 acgatctgaa tgaaacctat tatgtgcaaa tgtatcggaa tcttgagttt ggaaccattg
    14581 cttttaatat tacaggtgta gcgattccat tggctatttt tatttcatta agtgaggtga
    14641 ttatattgca tacaaaccct caaacatttt tcctttcttt cttactcttt gtggtattct
    14701 tagtcgctca aaaatctctt tttaaaacca ttgcgattgt tcgtcagttt gatttggaat
    14761 ttttcgctac accaaaggat gtcttgaact atataaattc ttatgatgaa ggggagcgtc
    14821 aggctaattt ggaacagagt tttcgaattt tattccaatt acaccaatat gtcttaccag
    14881 ccttatatat ttttcttatt atcatttctt tcttgacagg agagattcag ttactagctt
    14941 tcttgcttgt aggagccatc catgtttata tcaatgtgat gcagttacct atggtaaaac
    15001 gttatttcaa ataaaggagt tatctatgaa actacttaaa aaccttggct ggtttcttct
    15061 agcccttcta tcctttttct ttatctatgg ctttattcag gggctcgcga ctgcgtcgct
    15121 tgctttaggc gcttcaccct atgctgttac tctactctat gtggtcttgg ctggagtata
    15181 tgtgtacggc atttacaaat ggtatcagaa agctcctgtt tatattgaga agagcggctt
    15241 taaccgattt atttggcttc ctgccttggt ttggttttta tctctggtcg ttcaattctt
    15301 cttgccagat gatccttcag taaatcaaca aatagcgaca gacttgacct tgtctcaacc
    15361 acttttctca ttctttgctg tggttatttt tgctcctttg acggaagaga ttgtttttag
    15421 agggatgtta gcacgctatc tctttcctaa gcaggacaat agtaaacgaa ccctgatttt
    15481 tcttctggta tctagtcttc tatttgcctt gattcatttt ccaggtgatg tgcaacaatt
    15541 ttttgtctat tttagccttg gttttagttt gggtttggct tacattagca gaaaaggtct
    15601 ggtctacagt atttctcttc acgctttgaa taatttagtc ggctttttga tgattctcat
    15661 gctataatag agtcaggagg tcacatgaaa cgagtaattt tattagcagt gattcaggca
    15721 gtcgttctat ttttcatcat tggagcgcta gcttatgcct tcaaaggcga tttcttctat
    15781 aactatctag cagttgtctt tgctcctatt gcaggtgtac tgcgttttgg gacggcttac
    15841 ataacggaaa ttgtcttgcc tcgaaaggca gccgaaatcg ctgaaaagcg taaagcaggc
    15901 aaaaattcaa aataaaagag tccggtgaag ttcatcggat ttttgtatta tactcaatga
    15961 aaatcaaaga gcaaactagg aagctagccg caggttgctc aaaacactgt tttgaggttg
    16021 tggatgaaac tgacgaagtc agctcaaaac atggttttga ggttgtagat gaaactgacg
    16081 aagtcagtaa ccatacctac ggtaaggcga cgctgacgtg gtttgaagag attttcgaag
    16141 agcattagcg ctaattttta gggctttcac ctgactttta aagactggca aacttttctg
    16201 atgattttca tgaagagcct gcgcttttat ggtaaaatag taacagaata aaagaggaga
    16261 gaaataatga aacgtagtat gtatgctggt cgtgttcgtg aggaacacat cggacaagaa
    16321 ataaccttga aaggatgggt tggccgtcgt cgtgaccttg gtggtttgat ctttatcgat
    16381 cttcgtgacc gtgaaggaat catgcagttg gttatcaacc ctgaaaaagt atctgcagag
    16441 gttatggcaa cagctgaaag ccttcgtagc gaatttgtta ttgaggtgac tggtcaggtc
    16501 gctgcgcgtg agcaagccaa tgataagttg ccaactggtg cggttgagtt aaacgtgaca
    16561 gctcttattg tgcttaacac agctaagaca acaccatttg agattaagga tggcattgag
    16621 gcaaatgacg atacacgttt gcgttaccgt taccttgacc ttcgtcgtcc agaaatgttg
    16681 gaaaatctta aacttcgtgc caaggtgacc cactctatcc gcaactactt agatgagttg
    16741 gagtttatcg acgtggagac accattcctt tctaagtcaa cgcctgaagg ggcgcgtgat
    16801 tatttagtgc cgtctcgtgt taataagggg catttttacg ctcttcctca aagtccacaa
    16861 atcacgaaac agctcttgat gaatgctggt tttgaccgtt actaccaaat cgttaaatgt
    16921 ttccgtgacg aggacttgcg tggagaccgc cagcctgaat ttactcaggt cgacttggaa
    16981 acgtccttcc ttactgagca agaaatccaa gatattacag aaggcttgat cgcgcgcgtg
    17041 atgaaggaaa caaaaggcat cgaagtaacg ctaccgttcc ctcatatgaa atacgatgat
    17101 gctatggctc tttacggttc tgacaagcca gatactcgtt ttgacatgtt gcttcaggac
    17161 ttgacagaag tggtcaaagg tgtagacttt aaagtctttt cagaagcact tgctgtaaaa
    17221 gcgattgtgg tcaaaggagc tgcggacaac tattcacgta aagacatcga caagatgacg
    17281 gaagtagcca aacagtatgg tgccaaaggt cttgcttggg tcaaggtggt tgatggagaa
    17341 ttaaacggac cagttgccaa gttcttgact ggtatccaag aagaattgac aacagcgctt
    17401 gctcttgaag ataaggactt ggttctcttt gtggcggata cgcttgaagt ggctaatgca
    17461 acactgggtg cccttcgtgg acgtattgct aaagagcttg gcttgattga taatgataag
    17521 ttcaacttcc tttgggtggt tgactggccg atgtttgaat ggtctgaaga agaaggccgc
    17581 tacatgagcg cccaccatcc attcacactt ccacaggaag agactgctca cgaattagaa
    17641 ggtgatttgg ctaaggttcg tgccattgct tacgatatcg tcttgaacgg ttatgagctt
    17701 ggtggtggta gccttcgtat caaccaaaaa gaccttcaag aacgcatgtt caaggctctt
    17761 ggtttctcag ctgaagaagc caatgaccag tttggtttcc ttcttgaagc catggactat
    17821 ggtttcccac cacacggtgg tttggctatc gggcttgacc gttttgtcat gttgcttgct
    17881 ggagaagaaa atatccgtga agtcattgcc tttcctaaga acaacaaggc aactgatcca
    17941 atgacacaag ctccatcaac agtcgctctc aaacaactag aggaactcag cttacaagta
    18001 gaagaagatg aaacaaacaa aacgaattaa gcggtggcgc tattatctgc gccgctttgc
    18061 ttatcagata aaaattttac gtgtcttaca aagtatctct cgagaaaagt atgatgagaa
    18121 gatttcggcc tctctggtct atggtttttt atcagcagta gcagttaatt tctttttcca
    18181 accagggcat gtgtattcga gtggtgcaac aggtctggca cagattatct ctgccttgag
    18241 taatcactgg tttggttttc atattccgat ttcgctaagc ttctacgcca ttaacttccc
    18301 tttgatggtc ttagcttggt atcagattgg ccataagttc accgtcttta cctttatcac
    18361 ggtatctatg agttccttct ttatccagtt tgtccctgtg gcaaccttga cggaggatcc
    18421 cattatcaat tccctttttg ggggtgttgt tatgggtttg gggattggtt ttgctcttcg
    18481 aaacaatatc tccagtggtg ggacggatat cgtcagcctg actattcgca agaaaacggg
    18541 taagaatgtc ggtagtattt ctttcttggt aaatggaact atcatgctga tagcaggttt
    18601 gacctttggt tggaaatacg ctctttattc tatgattacc atctttgtct ctagccgtgt
    18661 gacagacgca gtctttacta agcaaaagcg tatgcaggcc atgattgtga caaatcatcc
    18721 agagaaggta attgaaaaaa tccataaaaa attgcaccgc ggagcaacca tgatccacga
    18781 tgcagaagga acctataatc acgagagaaa ggcagtttta atcactgtca ttacacgtgc
    18841 agagtttaat gaatttaaac agattatgac acaagtggat ccaagctcct ttgtctctgt
    18901 ctcggaaaat gttcatattc taggaagatt tgttgagata gataattagt gattaatact
    18961 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc gtaggtatgt tactgacttc
    19021 gtcagttcta tctgcaacct caaaaccatg ttttgagctg acttcgtcag ttctatccac
    19081 aacctcaaaa cagtgttttg agcaacctgc ggctagcttc ctagtttgca ctttgatttt
    19141 tattgagtat aaaaagatct tgggtaacaa ctcaatttca gaagaaaagg aagtaaatct
    19201 tcccacaata aaacgcatag tatcaagttt tttcaatacc tgatagtatg cgtttttgct
    19261 tttaacgact ttttgcccag tctcttattt ttcgataatt ttgtgggcga tcaattgacg
    19321 gtaacaaatt tgtttattgt ttttattatc attaataatc tggagaatag tttcaaggga
    19381 aacacgacca agctctaaac tattgatatc gacataggct gccaagttga gcttgggatt
    19441 aaccgagtca aagctgagaa cagggacatc cagctggtgt ttggcaatat agttacaaac
    19501 accttcagct aggaggctat cggttgtgat gatagcatca atttgtggat cgtgcttgaa
    19561 taatcgcttg ctaaatttat agcccttttc ttccagaaac tcgtcggcaa agtagatgcg
    19621 attgttgtca gtggtaagtt tgtaatgttt aagcgcctgt tcatagcccg ttaaacggtc
    19681 tttggtcacg aagagctttt tacttcctcc gataaaggca atgcgtttgc agcctttttt
    19741 gatgaaatat tcagtcgcat caaaaccagc ttgaacattg tcgttgtcga caagtgggat
    19801 gaaaggagat agagatttac ctaagataag gaaggggaac tgttcttctg cgacgagttt
    19861 tacgagaggg tcttcttctt gggcatagag aaagattagc ccatctacac gcttgccgta
    19921 gaccatttgt gaaatagcgt tgagacgctc cttctcatct ttccctgttg ctatttgaat
    19981 ggcatagtgg ttttcagatg cgacttgaga gatgccacgt agaaccgatg gaaagaaagg
    20041 attctggtag aaggcgtctg agtcatcagg aagaactaat ccgataacct gagtatagct
    20101 gcttaccaag ctacgagcgt taaggtttgg gtggtagttg agttccttca tagctttgcg
    20161 aacgcgtttt tttgtttcgt cgctaatggt tgatttattt tgaataacac gggttacggt
    20221 tgaaggcgaa acaccagcag ccttggccac gtctttaatc gtaacgggca taaaaatctc
    20281 ctatttatgg taatttggat cacggaaatg tgttttataa aagatagtga ccagatacag
    20341 aacaaaaaga atattttgta cagtaatcag ggttgtcata ttttggccaa ataatcccaa
    20401 aataagtgta atcagagtcg gcaatcctaa acagttcaag ataaagtgat agcactcttt
    20461 aaaggttcta aatgaaaaga ggcgtgattt cttagtgata taaaggagaa gactagctcc
    20521 tagagagacg ataaagaaat tcaaaccaaa gaggaagctc gcaccgagaa ctaggaagag
    20581 gctgatatag acacgatttt gttggtacca gtctttagaa attgcttggg tcaagctgtc
    20641 tttgcttttg aaactctcag tctgaatggc tcggtaagag atgcgggtca gttccttgct
    20701 ttccttgctg atgactagtt catttgtatc gaaatgcagt tgcaagtcct taggtaattc
    20761 cttgatttga cctggaccaa tcacaacaga aggggcttga ctagctgttc cagtataagt
    20821 taatgtgcca tcgacaattg tagcatgttc agagagatcc tggacaacct catttgtcag
    20881 aggttcatag acattatcga taaaagtttc tagcggatag gtctcctggg agctgttttg
    20941 gatagcaatg ggtaccatag acaagctgat aaggaagata ctggtaaaga gaagttgaaa
    21001 ccagttgagc tcgaaacgtt tggacagggg cttacgaaac ccccaaatac ttgaaaaata
    21061 ggaaaatgga tatggaagca taggtatctt tctaaaaggt gttttctata tgagtattat
    21121 tatatagaga aatgcgcttt atttcaagtc tagggggtaa attgcttgct acaaggatat
    21181 tatttacagt gacaatcgct aatagtcaat gaaaatcaaa gtgcaaacca ggaagctagc
    21241 tgcaggttgc tcaaagcaca actttgaggt tggagataaa gctgacgtgg cttgaagaga
    21301 ttttcgaaga gtataaaatg aaaaagggtg gcggggataa attatccctt gtcgccacca
    21361 cttgtaagtc ctgaaacaaa gttcttttgt aggaagaaga agagaataca gattggaagg
    21421 gcgatgagga tagcacctgc tgagaagtag gcaatcttca agtttttcgc attgttaacg
    21481 aaggtttgga gacctacggc aacagtaaag tattctttct cacgaagcaa gaaactagag
    21541 aggatgtagt ccccgaaagg tcccatgaag gcccagagag cttgtacggc aaccattggg
    21601 cgaacaagtg gtagaacaat ttgccagaag cggcggaagt gtcctgcacc gtctagtttt
    21661 gcagattcgt ctaaagacat tggcactgta tcgaagtagc ctttcatgag ccaagcattc
    21721 atcgggatac caccaccaac gtagaggaag atgaggaacc agttgtggtt aagggcgttc
    21781 aacataagcg ccataacgaa gaaggctgtc aaagcggcca tagttggcac catttggatg
    21841 atcaagaaga agaccaaact ttgtttacga gccaagaagt tgtaacggct gtaagcataa
    21901 ccagcaagta cgatgatact tgtttgaaca gccatggtaa ttaaggcgat aatcaaagtg
    21961 ttgaggtacc aagtaccgta caaggtttca gtgaagaggc ctttaaagtt atcaaaattg
    22021 aggtcgatat tagtatctag tttaaaggct gagacgttac ctgctttaaa ggctgacatg
    22081 atggtaatca acagtggata gataattaca attgatagac caatcaggta aaggtaagta
    22141 aggctttgag tcagtctacg tttgagttta attgagttat tcatcttaga cgtcctccat
    22201 atcaaatgcg tgtagtttct tgaatgcgat catagagatt gagatgacaa tgatagagat
    22261 aatcaaggta acagctgccg ccattgagta ttgaggagat gtacctgttg tcaaacggta
    22321 gatccatgag atcaagatat cggttgaacc agctccacct ccgacactac caggtcctcc
    22381 accattgaag aggtacatga tagagaagtt gttaaagttg aaggtgtatt ggctaatcaa
    22441 agtaggtgcc gcaacagcca aaatcattgg gaaagtgatg ttgcggaatt tttgccaagc
    22501 gttggcaccg tcaatataag ctgcttcgta aaggtcgtta ggaatagatt gcaagatacc
    22561 caaagtcaaa acgtagatgt atgggaatcc gagccaacct tgcatcataa tcaaggcaat
    22621 cttcgtccaa gttgggtctg ttttccaagg aataagagct ccatcaagga aaggaaggaa
    22681 tttagccaag attggcaata cttgagtgtt gatagcaccg acactatcgt taaacatgtt
    22741 tgagaatgtc aagatagtga tgaaggctgg gacagcccaa ggaagaagga aaataacacc
    22801 aaagatacgt tttcctttga taaatggttg gttggcaatg atagctgtga agataccaat
    22861 tacgatttgt aaagtagaag ctgccaaagc ccaaatgata gtccaagaaa gaacagaacc
    22921 aaaggcagaa cggaaggtac tcaagctcca aatgtttgta aagttggtca aaccaaccca
    22981 gtccaacaac ttgtttggtg gcaagtgttg gaagtcgtag ttggtaaagg cgatcatcaa
    23041 ggttacgata actgggaaga taatcgcgaa ggtcatggca acataagatg gaatgatcaa
    23101 gaggtaaggg aagccatttt cataaatccc tttgatcatg tctttgagtg tgcgtggaac
    23161 tggaattcca ttgttaatgc gttttgcaat cgtatgtgca tctttgatat ttgagaaata
    23221 aaagagtaca taaacgatta caaagattag atggaaggca ccacgaatca gcataaagag
    23281 ggaattatca cgacctggtt tgtcaccaag agtgatgagg ttgctcaatt caggggttgc
    23341 aagtgctagg aagtaaagga caaatacgat ggttacacta aggaagataa aacctttggc
    23401 tttttgttta ttgtaaatct gtcctaaccc aggaatgata gacagcaggg ctgctttact
    23461 aggttgttgc ttttccatat taactccttt cataggatac tactttttta taagaaagct
    23521 aaattatttg tgtctctatt gataaattca aagggggatt tgatttccac cccccttgaa
    23581 caaatttttt attcaccaaa tttttgtttg attgtttctt tgatcaatgt tacagcatcg
    23641 ttagcagctg ttttagcatc tttttgacca cttacagcat caaagagcat atttttcgct
    23701 ggatcccaaa ctgcagacat ttgagagatg tttggcagtg gttgagtgtt cttgaactgt
    23761 ttgataacag ctgttgtcaa ctcatcgttt ttaccttcag cgtatgaacg agcctcagta
    23821 ttagctggga tttcgttagt cttatcatat aatacttttt gttgttcagt tgcaacaagg
    23881 aagtctacaa atttttgaga agcttcaagg ttcttaacgg cttgaggaat gacccaagct
    23941 ttaccaccac cgaatgcagc atattctttt ccatttggaa gagttgggat agttgcaact
    24001 ccgtagttta ctttagcatc tttaaaggct tgagctttcc aaggtccgtc gatgatagca
    24061 gctgttttac cttcttggaa ttgagtttgg attaagtttc cagcaccttc tgtatcttgc
    24121 atacctttag gccatttttc gtaccaagat ttagcgtagt tgatacctgc gatagaaccg
    24181 tcgtttgcaa gaccgatgtc tttagcgtct ttaccgtttt ggccaaagac gtaagcaccg
    24241 ttaccggcaa gaagtccata tgtatagtag aagtttgtcc agtcagctag gaaggcagta
    24301 gttttaccat cttcaccagc gaatgcgtat ttgctatctt tagcaaggtt ttccaagtca
    24361 gcaaatgttt ttggagcatc tttcaccaag tctttgttgt agtacataac aagtgactcg
    24421 ataacggcag gagcaccgta aactttacca ttagcagctg ttacaagaga tttagttgtg
    24481 tcgtctgttt tagcaccatc gctcaatttc acttctgaaa gttgtccgtc agaaccaagg
    24541 ctacctacac ggtcgtatgg agccatcata acatcaggga cattaccaga ttggttgtca
    24601 agagaaagtt tatcaagacc tcctagagca tcaccagttt taagagtgac ttttactcca
    24661 gcttcttttt cataagcttt agcaacctct tcaatatagc tcttatatcc ctcgtctaca
    24721 tatacagtga gttctttgac ttcagatgaa ccagaatcag caggcttatc agcagttttg
    24781 cttccgcaag ctaccaaaag caagctagca agtgtaacag ttccaagcac cgcagtgctc
    24841 ttcataaatt tagatgacat agtgtattcc tcccaaagaa tagcaagttt tattgataag
    24901 gaaacgcaaa cgttttcctt tatgagctta gtatagcaca aatagaaaac ggttgcaagt
    24961 attttttgta aaaattttaa aaaattttta agcttgattt gatagcataa ttttgcattt
    25021 taatagaaga aaagtatgaa atagataaga atacagtatt tttaataaaa atatatggaa
    25081 tctgtctaaa gagggaaacc aggaggggct acctccctgg ttctaatccc tatctatttt
    25141 ctatggacgt ttgtgctttg ttacatataa attcaagctc cctaaggagg ttttgtactt
    25201 tgtagactgt ctcgtgagag tcaaacctta ggattagata gttttaagtt atctttgcta
    25261 aaatgagtta gtctccttaa aaataatcaa aaaagttttt taaaaacgct tgcaattatg
    25321 cttgaaaagg agtatactta taagtaacgc aaacgtttgc gtctgcaaaa tacgcaacgt
    25381 tccattattt taacacacga ggtgctatta tgaaaaaacg tcaaagtggt gtgttgatgc
    25441 acatctcttc tcttccagga gcttacggaa tcggatcatt tggtcaaagt gcttacgact
    25501 tcgttgattt cttggtccgt acaaaacaac gttactggca aatccttcca ttaggagcaa
    25561 ctagttacgg ggattctcct taccaatctt tctcagcctt cgcaggaaac actcatttta
    25621 tcgatttaga tatcttggtg gagcaaggtt tgttggaagc aagtgacctt gaaggagttg
    25681 actttggtag cgatgcgtct gaagttgact atgctaaaat ctactatgca cgtcgtcctc
    25741 ttttagaaaa agcggtgaaa cgtttctttg aagtcggaga tgttaaagat tttgagaaat
    25801 ttgctcaaga caaccaatca tggcttgagc tctttgctga gtatatggct atcaaagagc
    25861 attttgacaa tcttgcttgg actgaatggc cagatgcaga tgctcgtgct cgtaaagctt
    25921 cagcacttga aagctatcgt gagcaattgg cagacaagtt ggtttaccac cgtgtgactc
    25981 aatacttctt cttccaacaa tggttgaaat tgaaagctta cgctaacgac aaccacatcg
    26041 aaatcgttgg ggacatgcca atctacgtag cggaagattc aagtgatatg tgggcaaatc
    26101 cacatctctt caaaacagat gtcaatggta aggctacttg tatcgcagga tgcccaccag
    26161 atgagttttc tgtaactggt cagctttggg gtaatccaat ctatgactgg gaagcaatgg
    26221 acaaagacgg ctacaaatgg tggattgaac gcttgcgtga aagcttcaaa atctacgata
    26281 tcgttcgtat cgaccacttc cgtggcttcg aatcttactg ggaaatccct gctggttccg
    26341 atacagcagc acctggtgag tgggtgaaag gtccaggcta caagcttttt gcagccgtta
    26401 aggaagacct tggtgagcta aacatcatcg cagaagacct tggcttcatg acagatgaag
    26461 tgatcgaatt gcgtgaacgt actggcttcc caggaatgaa gattcttcaa tttgccttca
    26521 acccagaaga cgaaagcatt gatagcccac acttggcacc tgctaactca gttatgtaca
    26581 caggaacaca cgataacaat acggttcttg gttggtaccg taatgagatt gatgatgcga
    26641 ctcgtgagta catggctcgt tacacgaacc gtaaagaata cgaaacagtg gtacacgcta
    26701 tgcttcgtac agtattttca tcagttagct ttatggcaat tgcaactatg caagatttac
    26761 tagaattgga tgaggcagct cgtatgaact tcccatctac ccttggtgga aactggtctt
    26821 ggcgtatgac tgaagatcaa ttgacaccag ctgtcgagga aggtttgctt gacttgacaa
    26881 caatttatcg ccgaattaat gaaaatttgg tagatttaaa gaaataagac aataatcagg
    26941 agacaactaa acatgttatc actacaagaa tttgtacaaa atcgttacaa taaaaccatt
    27001 gcagaatgta gcaatgaaga gctttacctt gctcttctta actacagcaa gcttgcaagc
    27061 agccaaaaac cagtcaacac tggtaagaaa aaagtttact acatctcagc tgagttcttg
    27121 attggtaaac tcttgtcaaa caacttgatt aaccttggtc tttacgacga tgttaaaaaa
    27181 gaacttgcag ctgcaggtaa agacttgatc gaagttgaag aagttgaatt ggaaccatct
    27241 cttggtaatg gtggtttggg acgtttggct gcctgcttta tcgactcaat tgctactctt
    27301 ggtttgaatg gtgacggtgt tggtcttaac taccactttg gtcttttcca acaagttctt
    27361 aaaaacaacc aacaagaaac aattccaaat gcatggttga cagagcaaaa ctggttggtt
    27421 cgctcaagcc gtagctacca agtaccattt gcagacttta ctttgacatc aactctttac
    27481 gatattgatg ttactggtta tgaaacagcg actaaaaacc gcttgcgttt gtttgacttg
    27541 gattcagttg attcttctat tattaaagat ggtatcaact ttgacaagac agatatcgct
    27601 cgcaacttga ctctcttcct ttacccagat gatagtgacc gtcaaggtga attgctccgt
    27661 atcttccaac aatacttcat ggtttcaaac ggtgcgcaat tgatcatcga cgaagcaatc
    27721 gaaaaaggaa gcaacttgca tgaccttgct gactacgcag ttgtccaaat caacgatact
    27781 cacccatcaa tggtgattcc tgaattgatt cgtcttttga ctgcacgtgg tatcgagctt
    27841 gacgaagcaa tctcaattgt tcgtagcatg actgcctaca ctaaccacac aatccttgct
    27901 gaggcgcttg aaaaatggcc tcttgaattc ttgcaagaag tggttcctca cttggtacca
    27961 atcatcgaag aattggaccg tcgtgtgaag gcagagtaca aagatccagc tgttcaaatc
    28021 atcgatgaga gcggacgtgt tcacatggct cacatggata tccactacgg atacagtgtt
    28081 aacggggttg cagcacttca tactgaaatc ttgaaaaatt ctgagttgaa agccttctac
    28141 gacctttacc cagaaaagtt caacaacaaa acaaacggta tcactttccg tcgttggctt
    28201 atgcatgcta acccaagatt gtctcactac ttggatgaga ttcttggaga tggttggcac
    28261 catgaagcag atgagcttga aaaacttttg tcttatgaag acaaagcagc tgtcaaagaa
    28321 aaattggaaa gcatcaaggc tcacaacaaa cgtaaattgg ctcgtcactt gaaagaacac
    28381 caaggtgtgg aaatcaatcc aaattctatc tttgatatcc aaatcaaacg tcttcacgag
    28441 tacaaacgcc aacaaatgaa cgctttgtac gtgatccaca aataccttga catcaaagct
    28501 ggtaacatcc ctgctcgtcc aatcacaatc ttctttggtg gtaaagcagc tccagcctac
    28561 acaatcgctc aagacattat ccatttaatc ctttgcatgt cagaagttat tgctaacgat
    28621 ccagcagtag ctccacactt gcaagtagtt atggttgaaa actacaacgt tactgcagca
    28681 agtttcctta tcccagcatg tgatatctca gaacaaatct cacttgcttc taaagaagct
    28741 tcaggtactg gtaacatgaa attcatgttg aacggagctt tgacacttgg tactatggac
    28801 ggtgctaacg tggaaatcgc tgagttggtt ggagaagaaa acatctacat cttcggtgaa
    28861 gattcagaaa ctgttatcga cctttacgca aaagcagctt acaaatcaag cgaattctac
    28921 gctcgtgaag ctatcaaacc attggttgac ttcatcgtta gtgatgcagt tcttgcagct
    28981 ggaaacaaag agcgcttgga acgtctttac aatgaattga tcaacaaaga ctggttcatg
    29041 actcttcttg acttggaaga ctacatcaaa gtcaaagagc aaatgcttgc tgactacgaa
    29101 gaccgtgacg catggttgga taaagtcatc gttaacattt ctaaagcagg attcttctca
    29161 tctgaccgta caatcgctca gtataacgaa gacatctggc acttgaacta atactcttcg
    29221 aaaatctctt caaaccacgt cagctttatc tgcaacctca aagcggtgct ttgagcaacc
    29281 tgcggctagc ttcctagttt gctctttgat tttcattgag tataagatac aaatttatac
    29341 taatacatct tgtaaaaaag cgagtttcga ttgaaattcg cttttttaat gatgtagatt
    29401 tgggtcaatc ttgtctaaaa atagggaaat cctagataca gtgaaggctt taaatgctgg
    29461 tttttactgt cctcagcctt atattttttc gtagttgatt acctcatacc tcttgtattc
    29521 gcttacataa agtattataa tataattgta ggaaagaagg tgtttttatg atatacacac
    29581 ttaaattggt gttgtttatt acctttcttg taataagctt gttacctgat aagatttttg
    29641 gaaaaaataa aaaaatttgg aaaatagttt ttgcaatatt gacggcagtg gcagcattgt
    29701 catttatgta ctaagttatt ttaagaatgt agggaaataa accctacatt ctttttagtt
    29761 ttttctgttt tctaaattct atttatccaa gcgcttcaac atttcttgct tcttcgcttc
    29821 aagttctgca cgcttttctt cgatttcggc atgttttttc tcgagttcag aacaacttgc
    29881 accattgcta aattcttttc gccatcagga gatagggtga gtcgacatgt ttattactca
    29941 cccaaagcag tcctacaaag caggaatttt ctgttacttt tttggaaata gtaacgttta
    30001 tacagctttg acacttcgta tcaaagcgcc aaacacactc cgagggattt acagaaagca
    30061 gaaaaggaat gatctggtat aagatcattc cttttctctc tttttcttta agtaattata
    30121 tacaatgtac gacgaagtcg tcattgcaat gctgatccac cacctaaagg gaactttaaa
    30181 caacattgat aagataaaga atataaacaa cgaaaatacg ttatacccaa ttaattttat
    30241 tgtatatctc atgattaaaa gttaatcctt ccgttgttag gaatggcatc atttttatcc
    30301 cataattgtg ctaaataagt ccccgatgat aataaattca tagcgaattc taaagcaaca
    30361 tcatttacaa accaactaac tagatatcta gaaattgctg aacgaatagc actttttgct
    30421 gcatgttttc cttttacttt aattagattt gcaaggcctg cagtagttcc tcctaatgct
    30481 aaagctattg cagtatctaa tagagcaccc atttgattaa ctgtaatacc ttgccaagct
    30541 gctctaaatg gagagtatgt aggtgggatt gtataatcgc cttgtaattg tcggttaatt
    30601 acttctttga tccattgttg tgagacgtct ggatgaaaag attggatttc gtttgcaagt
    30661 gtatttattt gttcttctgt tagagaagtg acaggttgaa gttccatatt tgtttcaatt
    30721 tgtgatactt gttcagaagc gtatacagct gaaacacttg gaatcgctga tacaattaac
    30781 acaattgacg tcaaaaaaac cgaaataaat ttcattaatt tgttcatgag cttttctcct
    30841 ttttatttgt atctgcttac attttatcat atactgttat tatagtcaaa aaaatatgct
    30901 attatgttaa aaaaatattt ttcaaaatat aaatggacgg atttattttg gattttattt
    30961 gttattttga cctgcctcta tattggtaac catgatttgt ttactctcaa tcatcaagaa
    31021 ttctcttttc gtggtagcgt ttggggtctg gtactggcct tatatcactt actattcatt
    31081 gataagtttg ttatatcgaa tcgaaaataa agattagagc tatgcttgac tgtgtacttt
    31141 taggattgat tttggaggaa gattttgtct ctattattta ttattttaaa tttatttatt
    31201 ttgtataaga tctattcttt gaggcgggaa aaatcgaaat acttgattta tacggcctat
    31261 atcatatttg gggtaaatgt agtatatggt attcaatggt tattaagaga actgatttca
    31321 actatttccc cttaatgtgt atggaaacta taacaaaacg cataagatta aggtttgtgt
    31381 acctgttctt atacgttttt gtcatattga agattttcgg taagttttct acttttgcga
    31441 agtctagttt atactcaatg aaaatcaaag agtaaactag ccgtaggttg ctcaaagtac
    31501 agctttgagg ttgcagataa aactgacgaa gtcagctcaa aacatggttt tgaggttgta
    31561 gatgaaactg acgaagtcag taaccatacg tacggcaagg cgacgttgac gtggtttgaa
    31621 gagtattaga atgctttccc aaccaaaatc tctgcttcga tggtaatctc tgtcagtttg
    31681 ctccagtcaa ttttgctctg gtcaacgtga aagaggagag gagtcatact gagtagggct
    31741 tggagttgtt ctgctgtgat agtcttagtc agagaggcag tttgactaga taggatggta
    31801 aagtgttcct ggaaatgctc cttgatatct tggttagaat actccttgtt tgtcagctgg
    31861 tcctgtactc tttgacggat ttctttgagg tgattttcag ttgggataac ctttatcaag
    31921 ataccgtctt tggataaaac gcgacgaaat tctccatagt tggcaggtga gaagatatca
    31981 agcagaatat ccatgttatc gtcttttata ggaagtcgtg ccaagtcgcc aacgaaccaa
    32041 ttgactgccc agttgggttc acttttagca gcgatttgga ctgaatcttt ggagatgtca
    32101 aaggcataga aagttttttc agagtgactt tcttgtagtt tgcgagaata gaatccttca
    32161 ccacaaccga tatccaaaat tgttgtggta gtttttgagc ttgcaagcaa gtcagataca
    32221 gcatctaaga tagcttggta aaagccggct tctaggattt gttgacggtt ttgaaaattt
    32281 tccttgtcat agttagcaga ttgcttgatt tgaggtgcta gattgacata gccaaatttc
    32341 gccaagtcaa aagaatgacg gttgcagcac ttgaaattag tctctaacag agtcagattt
    32401 tcttgacaga taggacaggc aaaggcagtc gcagaagcaa aacgctgaag tttgggcttg
    32461 agatttgtat tcatagttta agtgtatcaa aagaggcaaa tgaaagcaac tttaggaata
    32521 agtagatggg agattcagta gaaataaaac taattctcca atttatagaa tgaaattgct
    32581 tttatatcta aattgctata taataatgat aaggaggaaa taagtatgtt aaaagaagta
    32641 ttaaccgttg caaaagttgc gaaaaaatct tcattatttt tgggtggtgt cgcatttggt
    32701 acccttggtt tgaaaatctt agcaagtaag gaagctaaaa aaggttattc taaagctttg
    32761 gctaaggctt acaagttgaa agacgagcta gatgcatctg tttctgtcgt gaagcaacat
    32821 ggagacgatg tcttgcaaga tgccaaatat ttgtacgagc aagagaaaaa agaagagcaa
    32881 ttagatagcc ttataggtga ataatatgtc ttttaaagtg ctacatagag gataccaaca
    32941 tatccgacta tcatcttctt tttcacttac cttggatatt caagactatc ttcgttcctt
    33001 ggcgagagat gaaaagggga ttgagtctat ccagttttac atggatcaac agcactttac
    33061 tctacgcata aaagaaggct tttctgtatt agataatgca gaagcctttt taaaaagaat
    33121 tgataaaggg aaagtttctg agttgatgac tcttcccatt cgtagagaag agagtgctta
    33181 ttctattgtt tcaggtgcag cggttaagcg tgtacttttt cgtagttttg tgccgtatcc
    33241 tattcgctat atatggactt gttatcaggc tttgggttat attagagaag cctatcaaac
    33301 actagcgcgt aaggaactaa cgatggaagt cttggactgt tcggctattt tattgtcttt
    33361 gtttatgaac caatccaaga cagctagcaa tatcatgttt atgcttgatt tggggaatca
    33421 tttagatcag tggtccttga aaaaaactgc aacagattta gaacagagtc ttcttgcaaa
    33481 agagagcgat gtattcctag tacagggcga tacagttgtt agtatcaaga gttccgatgt
    33541 tcaaatagga gatgtcttga tcttatctca aggaaatgaa attctgtttg atggacaagt
    33601 agtttcaggt ttaggtatgg tcaacgaaag ttccttgaca ggagagagtt ttccagttga
    33661 aaaaagagag tctgatttgg tttgtgcaaa tacagtatta gaaactggag agttacgcat
    33721 ttgtgtaaca gataatcaga tgaacagccg tattttacag ctgattgagt tgatgaagaa
    33781 atctgaagaa aacaagaaaa cgaaacaacg ctatttcatc aagatggcgg ataaagtcgt
    33841 caaatataat ttcttggggg ctgggctgac ttacctattg acaggttctt tttctaaggc
    33901 tatttctttc ctattggtcg atttctcctg cgctttgaaa atctctactc cggtagctta
    33961 tttgacagtt atcaaggaag ggttgaaccg tgaaatggtg attaaggatg gagatgttct
    34021 ggagaaatat ctggaagttg atactttctt gtttgataag acaggaacaa tcacaactag
    34081 ttatcctata gttgaaaagg tgttaccttt tggagactat agtgaggaag atattctcag
    34141 aatcagtgcc tgtcttgagg aacacattta tcatcctatt gctaatgcca tcgtcaagca
    34201 agctgagata gagggaattg aacatgagga aatgcatggg aaactccaat atatcgcaag
    34261 caaggggatc aaatctcata tagatggcca accagttctt attgggaatt atgtcttgat
    34321 gcaggatgag cagattcata tcagttcaga acaaaatgct ttaattgaag agtacaagag
    34381 tcactacaat ctcttattct tggcttatca aaatgaattg attggaatgt tctgcattca
    34441 tactcctttg agaaaagaag caaaaacagc cttggataaa cttaaggcac aggggaaaaa
    34501 attgattctg gcaacaggag acaccttgat taggacagag gaattagtca aagatttgcc
    34561 ctttgatcag gtctatacag acttgaaacc tgatgggaaa tttgagttag tagagaaact
    34621 gcagaaagca ggtcacacta ttttgatggt tggagatgga ttgaatgact cagcggcttt
    34681 aactctatca gatatcggtg tggtgatgaa tgagagtgca gatatttcta agcagatgag
    34741 tgatatctta ttgttagata atcgtttgga tttcttccaa gagttggatt cgttatcatc
    34801 atctttgcaa acactcatca agaaaaatat tcaggatacc gttgtcgtaa atagtagttt
    34861 gattggcttt ggcttattta attggttcag tccttcaaat ctctctatct tacataatct
    34921 aacaaccttg cgcattgtcc tgcgtagcct gtctattaaa aatagataga tgagagttat
    34981 taacagcaaa aaggagttac ctttctcgag gttaactcct ttgtttatag ataaatgttg
    35041 aatagtttag taagtcaata caaagtattt tttcttccca cgacggataa cagtcagttc
    35101 attttctaac ttatcagcgt cactcaagac atagtcaagg tcttggatgc ggtcgccgtt
    35161 tacgtagatg gctccgtttt ggacgtcttc acgggcttgg cgttttgagt taactatacc
    35221 agatgagacg agcagttcca cgatattgtt gttttcgtct gcctgtactt ggtagtttgg
    35281 cacaccacga agtccttgtt tgagctcttt gacagaaagg tttttgatgt ttcctgcaaa
    35341 gagttgctca gtgatgttaa gtgcttcttt gtaggcttct tctccgtgaa caagtgtaac
    35401 aacttcacga gccaagactt tttgagccaa gcgttcgtgt ggcgctgctt caaattgttt
    35461 acgaatatct tcaatctcat caagtgacaa gaaagtaaag attttcaaga agcgaacagc
    35521 gtcagcgtcc atcacgttca tccagaattg gtacatttcg tatggagaag tcttttcggg
    35581 attgagccag acggcatttc cttctgattt accaaatttt ttaccagttg catctgtgat
    35641 tagtggaaca gtgataacgt gaccagtctt gtccgcctta cgacgaagca attcggtacc
    35701 agctgtcata tttccccact ggtcagaacc accgatttga agagtgacat tatggtcttg
    35761 gttaaggacg aagaagtcgt acccttgcat gatttggtaa gcgaactcag tgtaagaaat
    35821 tcctgtttcg atccgttttt taacagattc cttactcatc atgtagttga ccgtgaagta
    35881 ttttccaata tcacggagga agtcaatgaa gctgatgctg ccaaaccagt cgtagttgtt
    35941 gaccatgaca gccttgtttt cgccattttc aaagtcaaga aaacgagaaa gttgtccttg
    36001 gatagacttg acccagccat ctactgtgtc ttttgtttgg agactacgtt cagcatcttt
    36061 gaaggacgga tctccgatga gacctgtagc accgccaacg agcgcataag gtttgtgacc
    36121 tgctagttgc aagcgacgac ttgtcaagat tgcgacaagg tggcctaggt gaaggctgtc
    36181 agcagttgga tcgtagccag tataataaga aacttgacct tcttctaggg ctttacgcaa
    36241 agcttcttca tcagtcgttt gaaatatcaa accacgctct tttagctcat caaaaatgtg
    36301 catgtgtctt ttctcctttt taaaattatt gtttctacct attgtatcac aaacttgggc
    36361 aatagcctag cagaataggg aagaaagtgg ctattttatt gaaaatttcc cttttgtggt
    36421 ataatagata aagtgaggaa atccatgcaa aatcaattaa atgaattaaa acgaaaaatg
    36481 ctggaatttt tccagcaaaa acaaaaaaat aaaaaatcag ctagacctgg caagaaaggt
    36541 tcaagtacca aaaaatctaa aaccttagat aagtcagcca ttttcccagc tattttactg
    36601 agtataaaag ccttatttaa cttactcttt gtactcggtt ttctaggagg aatgttggga
    36661 gttgggattg ctttggggta cggagtggcc ttatttgaca aggttcgggt gcctcagaca
    36721 gaagaattgg tgaatcaggt caaggacatc tcttctattt cagagattac ctattcggac
    36781 gggacggtga ttgcttccat agagagtgat ttgttgcgca cttctatctc atctgagcaa
    36841 atttcggaaa atctgaagaa ggctatcatt gcgacagaag atgaacactt taaagaacat
    36901 aagggtgtag tacccaaggc ggtgattcgt gcgaccttgg ggaaatttgt aggtttgggt
    36961 tcctctagtg ggggttcaac cttgacccag caactaatta aacagcaggt ggttggggat
    37021 gcgccgacct tggctcgtaa ggcggcagag attgtggatg ctcttgcctt ggaacgcgcc
    37081 atgaataaag atgagatttt aacgacctat ctcaatgtgg ctccctttgg ccgaaataat
    37141 aagggacaga atattgcagg ggctcggcaa gcagctgagg gaattttcgg tgtagatgcc
    37201 agtcagttga ctgttcctca agcagcattt ttagcaggac ttccacagag tcccattact
    37261 tactctcctt atgaaaatac tggggagttg aagagtgatg aagacctaga aattggctta
    37321 agacgggcta aggcagttct ttacagtatg tatcgtacag gtgcattaag caaagacgag
    37381 tattctcagt acaaggatta tgaccttaaa caggactttt taccatcggg cacggttaca
    37441 ggaatttcac gagactattt atactttaca actttggcag aagctcaaga acgtatgtat
    37501 gactatctag ctcagagaga caatgtctcc gctaaggagt tgaaaaatga ggcaactcag
    37561 aagttttatc gagatttggc agccaaggaa attgaaaatg gtggttataa gattactact
    37621 accatagatc agaaaattca ttctgccatg caaagtgcgg ttgctgatta tggctatctt
    37681 ttagacgatg gaacaggtcg tgtagaagta gggaatgtct tgatggacaa ccaaacaggt
    37741 gctattctag gctttgtagg tggtcgtaat tatcaagaaa atcaaaataa tcatgctttt
    37801 gataccaaac gttcgccagc ttctactacc aagcccttgc tggcctacgg tattgctatt
    37861 gaccagggct tgatgggaag tgaaacgatt ctatctaact atccaacaaa ctttgctaat
    37921 ggcaatccga ttatgtatgc taatagcaag ggaacaggaa tgatgacctt gggagaagct
    37981 ctgaactatt catggaatat ccctgcttac tggacctatc gtatgctccg tgaaaatggt
    38041 gttgatgtca agggttatat ggaaaagatg ggttacgaga ttcctgagta cggtattgag
    38101 agcttgccaa tgggtggtgg tattgaagtc acagttgccc agcataccaa tggctatcag
    38161 accttagcta ataatggagt ttatcatcag aagcatgtga tttcaaagat tgaagcagca
    38221 gatggtagag tggtgtatga gtatcaggat aaaccggttc aagtctattc aaaagctact
    38281 gcgacgatta tgcagggatt gctacgagaa gttctatctt ctcgtgtgac aacaaccttc
    38341 aagtctaacc tgacttcttt aaatcctact ctggctaatg cagattggat tgggaagact
    38401 ggtacaacca accaagacga aaatatgtgg ctcatgcttt cgacacctag attaacccta
    38461 ggtggttgga ttgggcatga tgataatcat tcattgtcac gtagagcagg ttattctaat
    38521 aactctaatt acatggctca tctggtaaat gcgattcagc aagcttcccc aagcatttgg
    38581 gggaacgagc gctttgcttt agatcctagt gtagtgaaat cggaagtctt gaaatcaaca
    38641 ggtcaaaaac cagggaaggt ttctgttgaa ggaaaagaag tagaggtcac aggttcgact
    38701 gttaccagct attgggctaa taaggcagga gcgccagcga caagttatcg ctttgctatt
    38761 ggtggaagtg atgcggatta tcagaatgct tggtctagta ttgtggggag tctaccaact
    38821 ccatccagct ccagcagttc aagtagtagt tctagcgata gcagtaactc aagtactaca
    38881 cgaccttctt cttcaagggc gagacgataa ttctctaaat gaagtggcca atcaatggat
    38941 tgccactttt ttcttttcgt gttacaataa gggtatgaat cagtatcaga aaaagattgt
    39001 taacggaaaa atttattcgc tcctatccgg cttaatatgg ggaatctgtg gaattttagg
    39061 agagtacttc tttactcatt atcaggtgtc ttcgggctgg attacctcta tgcgtttgac
    39121 actggcaggg agtcttgtac tcatttggtc tgcaatacaa ttaaaatcgc aagtgctaga
    39181 tatttggcga gacaagaaaa attacctgcc ctttttagcc tatgctattt tggggatttt
    39241 ttcagttcag tattttttct atctctgtgt agaatactca aatgctacga cagcaactat
    39301 tttacagttt attagccctg tctttatcct cttttacaat cgcttggttt atcaaaaacg
    39361 agcgtcaaaa agcgctgttt tctatgtttt ggttgccatg ctgggtgttt gcttgatggc
    39421 gacaaaggga gatctctctc agttatccat gacgccgcta gctcttataa caggtttgct
    39481 gagtgccatg ggtgttatgt ttaatgttat cttgccccaa ccttttgcta agcgttatgg
    39541 ttttgttcct acggttgggt gggggatgat tttggcaggt ttgtttagca atgtcctctc
    39601 gccggtttat cagctttcct ttactcttga tatttggagt atcttgattt gcctcattat
    39661 cgctttcttt ggaacggctt ttgctttttt catttccatg aaggctgtgt ccttggtttc
    39721 tcctttggtg gttgccgtta tcagtgccag tgaacctctc tcttctgctc tcttgagtgt
    39781 tttgttctta ggattagtag tggattggtc cctccttcta gctatagcct tgattatttt
    39841 acccatgata tttttgtcta tagaagaagc gaaagaaagt agataaaaag tcttttctta
    39901 attctaaaag tgtgctatac tagaatagtc aataaaacac ggggagatag ttgtgaagag
    39961 tgtttttagg ttgtatcggt aggggcttgc ttttaccgac agcacgtttt atctcacatc
    40021 cctaaaaaat catacctaaa aacagacaaa aaggtttcaa atttgaggcc ttttttggta
    40081 gaataggtat cattataacg aaccaggagg cacctatgac tgctacaaaa atgaacgctc
    40141 aagaaattat ccaatttatc gccaatgctg aaaagaaaac cagtgtcaaa gtaacctttg
    40201 aggggcaact cgcaactgct gtgcctagct ctgttgtcaa actaggaaat gtcctattcg
    40261 gagactggaa ggacgtggct ccgcttcttg aaggtttggt agaaaatcaa gattatgttg
    40321 tcgagcaaga tgctcgtaat tctgcagttc ctttgctaga taagcgtgct atcaacgctc
    40381 gtatcgagcc aggtgctatt atccgtgacc aggtggaaat tggtgacaat gctgttatca
    40441 tgatgggagc tgttatcaat atcggtgctg aaatcggtgc tggaaccatg attgacatgg
    40501 gtgccatcct tggtggccgt gccatcgttg gaaaaaatag ccacgttggt gcaggtgcag
    40561 ttttggcagg tgtgattgag ccagctagtg ctgaaccagt ctgtgtcgga gacaatgttc
    40621 tcatcggggc taatgcagtg gttatcgaag gagtccaaat cggtagtggt tcagttgtcg
    40681 cagcaggagc tattgttacc caagatgtcc cagaaaacgt ggtagtagca ggtgttccag
    40741 ctcgtattat caaagaaatt gatgcccaaa ctcaacaaaa aacagcgcta gaggatgcgc
    40801 ttcgtacctt gtaattgtaa aagtaaaaaa gaggcggaac cctttttcca gcctctttct
    40861 gctatatcgg aggacagata gatgttagat ttgattcaga ctagacgaga tttacaccag
    40921 attccagaga ttggcttgga ggagttcaag actcaggctt atttgctgga tgtgattgag
    40981 aaattgacta cgggcaagga ttttgttcaa attcgtactt ggcggacagg gattttggtc
    41041 tacctgcagg gaagtcagcc ggagcgaacc attggttggc ggacagatat tgatggcctg
    41101 cctatcgtcg aacaaacagg tctacctttt gcttctcaac accaaggtcg catgcatgcc
    41161 tgtggccatg attttcatat gaccattgcc ttaggctgtc ttgagcgcgc ccttgaagag
    41221 caacctaaaa ataatctgct cttcctattt cagcctgctg aagaaaatga agctggtggt
    41281 atgctcatgt atgaggacgg tgcttttgga gattggttgc cagatcaatt ctatggtctc
    41341 catgttcgtc cagatttgaa agtcggccag attgcgacta atactcatac actctttgca
    41401 ggaacttgcg aggtgaagat ccgtttcaaa ggcaaaggtg gccacgcagc ttttcctcat
    41461 gaagccaatg acgccttggt ggcggctagt tactttgtga cccaagtgca gtcagttgtt
    41521 agccgcaatg tcaacccaat cgagggagca gtggtgacct tcggcgtttt tcaagctgga
    41581 accaccaaca atgtcatcac agacacagct tttttacatg gaactattcg tgccttgaca
    41641 caggacatga gtctcttggt gcaaaagagg gtaaaaacag ttgcagaagc ggttgcagct
    41701 gcctttgata tggaagtcga agtggaactc aaacaaggtg gatacctacc tgttgagaac
    41761 aatccagcct tggcgcgtga actgatggac ttctttgacg aaaaagacgg aatcgagttg
    41821 attgatatcg aacctgctat gacaggcgag gactttggtt atctcctttc aaaggttgat
    41881 ggtgtgatgt tttggctagg tatcgatagt ccctacgctc ttcatcaccc tcaaatgagt
    41941 cctaaggaag aagtcttagc tattggggtg gctgcggtgt ctagtttcct gaaaaagaag
    42001 gcagcagaat agagggcttg tctatgaaat cggaattacg caagcaagtc ttgcatgaaa
    42061 tgaaggcttt atctcaagaa caaaaacagg ctatagacca agctttaacc gagcgaattt
    42121 tacaacaccc cttttatcaa gaagccaagg tcatcgcaac ctacctctct ttttctcatg
    42181 agtttcaaac gcgggaactg attgagcagg cgctgaagga cggcaagagg gttttgacac
    42241 ctaagaccta tcccaagggg cgcatggact ttgtggtcta tgatccgcaa cagttggtaa
    42301 aaacttcctt tggattactg gagccacagg gagatttgga agttgtggat gtttcaaaga
    42361 ttgatttgat tcatgttcct ggtctggctt ttacgacgaa aggatatcgg ataggatacg
    42421 gtggaggcta ttatgaccgc tatctggaac atttttctgg tcgtgctttg agtacgatat
    42481 atccttgtca aattcaggac tttatacctg aaaaccatga tattcctgtt caggaggtat
    42541 taattgatga aggaaatctt tgatagacgt taccctgtga cgagtttctt cctcttagtg
    42601 acggccttgg tatttttact aatgttggtc actgcaggcg gaaactttga cagggcagat
    42661 acattatttc gatttggagc catgtatggt ccagctattc gcctctttcc cgagcaggtt
    42721 tggcgtctct tgtctgccat ttttgttcat attgggtggg aacatttcat tgttaatatg
    42781 ctttcacttt attatcttgg aaggcaggta gaggagattt tcggttctaa gcagtttttc
    42841 tttctctatc ttttatcagg aatgatgggc aatctctttg tttttgtatt tagtcctaaa
    42901 tccttagcag caggcgcctc tacctctctt tatgggctat ttgccgcgat tattgttctt
    42961 cgctatgcaa ctcgcaatcc ttatatccaa cagctagggc aatcttatct gacacttttt
    43021 gtggttaaca ttattggaag tgttctgatt ccgggaatca gcctagcagg ccatatcggt
    43081 ggagcagttg gtggcgcatt tctagcagtt atctttccag ttagaggaga aaaacggatg
    43141 tataacacca gccagagatt aggagcggta gtcttgttcg taggactcgc cattttgctt
    43201 ttctacaagg gaatgggaat gtgacgaagt tgaaagaaaa tttgtgtaat gaaaaaagat
    43261 aaggcatttt ttgaacctta tctttttatt ttattccttc tcagtcaatt cttttccaag
    43321 ttggatgagg taattcttca aatcatcttt gacttgtgga tgtttgaggg cgtagtcaat
    43381 agatgttttc ataaagccaa acttatcccc aacgtcgtaa cgagctcctg taaattcacg
    43441 ggcaaaaaca cgctgtgttt tattaagagt atcgattgca tcagtaagtt ggatttcatt
    43501 tccagcacca ggagcttgct tttcgagaat ctcaaaaatt tctggtgtga gtagatagcg
    43561 accgatgatt gccaaatcac ttggagtctc ctcgggagct ggtttttcaa cgaaagtttc
    43621 aacgctatag agtccattgc ttccttcgcc ttgaggagca atgactccat atgatgaaac
    43681 gtcttcgtgt ggtacgggca tgacagcaat ggttgatgcg tgtgtctttt cgtaatcatt
    43741 catcagttgt tttgtcaaag gaacggcctt ctcgtctgtg atatccatca agtcatcacc
    43801 aagcataacg acaaaaggtt catttccgac gaaagccttg gcttgcaaaa cagcatctcc
    43861 gagaccgcgt ggatgagttt ggcggatgaa atgaaggcgc atgccagttg tttcatctac
    43921 caattttaac aaatccgttt tgcctttttc cttaagattg tattcaagct caaagtttga
    43981 atcaaagtgg tcctcaatag aacgttttga tttaccagtg acaactagaa tatcttcaat
    44041 acctgatttg agagcttctt ccacgataaa ctggatagtt ggtttgtcta cgattggcaa
    44101 catttctttg gcaagggcct tggttgctgg taaaaatcga gttcctagtc cagcagcagg
    44161 gatgactgcc tttctaactt ttgatgtcat aaaaatcctt tctatagagg gttaagacca
    44221 ctcattttct gctttaaatt cattgttcat gatgtcataa atggcatctt tgatattggt
    44281 tccgtgataa ataacttggt aaatagcctg tgtaatgggc atatagactc caagttcttg
    44341 ggctagttca taggctgatc gagtcgttga aattccttcg attaccatgc ccatattagc
    44401 ttctatatca gctagggatt ctcctcgtcc gagagcatct ccagctctcc agttacgaga
    44461 gtggatggaa gttcccgtta cgatcaaatc tcccacacca gataagccgc tataggtcaa
    44521 tggactggcc ccgagtgcta cccctaggcg ggtgatttct gctaaacctc gagcgatgat
    44581 ggctgcctta gcattatcac caaatccaag accatgtaaa gctccagcac cgacagcaat
    44641 aatattttta agagcaccag cagtttcaac cccgataaca tccgtattgg tataaagtcg
    44701 gaagtagtga ttactaaata gctcctgaac gtattgagct gtttgtaaat ctttagaagc
    44761 agcagttatt aaagttaggt cacgcacaat ggtctcttct gcatgactag gccctgaaac
    44821 aacgacgata tcactacgga gatgttcagg aatttcttct tcaagaatgg ttgataatcg
    44881 tttatggcta tcaggttcta atccctttga tgcgtgcatg atgataacct tatggtccaa
    44941 ggtttgtgca acttgctggg caacaagtcg tgtcactttt gttgggacaa caaacaaaat
    45001 cgcatccaca tttttcaatg tttctgctaa gtcggtgtag gcaatgatat tttcgtctag
    45061 aacgacatct ttaaagtagt gcttattagt atggtgtgta ttaatttcat tgatttgctc
    45121 gggaagattt ccccaaatac gtacctcgtg tccattgtca tttaagactt gtgaaagggc
    45181 ggttccccaa gaaccaggcc ccaagacggc gacggtttgt ttttccatga tttcctcctt
    45241 gatagatttc tttctcttat tatatcatat tctaggggat tttgcacttg cattactggg
    45301 gtatggtgga aaaatacaca aaaaccgaga tgaagggata aactcttagt ctttagttaa
    45361 agtgagaaga aatctgatag atagtttgat tcagtatatg ctataaatag aggtaaacaa
    45421 ctcaagaggt tcttgtaggt tgcgagagtt tggcgaaaaa attaaaagat tacgtttggc
    45481 taaaaaaatc agtcgttcag aattttgtgg tgatgagtct gaattaagta tccgtcaatt
    45541 aattagaatt gaaaatggag aatccagacc aacactaaca aagttaaaat atatcgctga
    45601 acgtttgggg gttgaagatt acaagttgat gccaagttat atagagttgg ataaggaata
    45661 cctagaattg aagtatttct tgatgaggac tcctacatac gaagatgaaa ctatcgccca
    45721 aaagaaagag agtgtttttg ctaagatttt tgaagagtat tatgataggc tacctgagga
    45781 agaaagattt atcatcccaa attattcata tctggcacta acgaactaca cagttcaaaa
    45841 attaccagaa aagctagttg aaatactgtc cttctggtga ttttgcttaa tttctgatgt
    45901 tcgagacatg attgaggaga tttgtcttga tttgttccta aaaagggcag actcctccct
    45961 tggtttgatg atcgattttt aaaataaggt gacttattct gttaggcatg ttttcccctg
    46021 ccctctagct ctatatggaa cagggagtat cagatttatc tggcagattg tatcaaataa
    46081 ggcttgaaac tgttttgaat aggcgtatag acttgagaat ttgagaatat gtcgtctagc
    46141 agtagagaca tattttccgg caatatgaag gaagagacgt cgaaaacgct tgatagtcaa
    46201 ggcctttact tcatcaccag ctagctgttt taaaaagagg tagagattat aagccagaca
    46261 gcccatcatc atacgtattt cattcttaat catggtcgaa ctatctgtct tatccccaaa
    46321 gaatcctgct ttcctttctt tgataaagtt ttcagcattc cctcgttcac gatagaattg
    46381 aaacagctcc tcactatcta cactgcttaa attggtcaaa tgaacttttt tacaaccata
    46441 aaaaagagca cttaatcgta ctcttctctt ttaaggatta gttgaattaa ttcaaatcca
    46501 ctagttctcc tgtttctagg tagactaggc gttcacaaat gttagcaatg taatcagcga
    46561 agcgttccag atgccctatg atataaaggt attgtgttcc attgggaatt gaggtttctt
    46621 ggtctttcat aagtccaatg atttcctttg ataaggcata ataatattgg tcaatctgtt
    46681 catctttttg agcaatacta atagcttttg aggcttggtg caaaggaaag gcaaccaata
    46741 aatcggctag catgctgagg gataatttac ccatttggtg taactgttct tcgccagggg
    46801 ctagttgatt ttcttttagt tgcaaaacag ctttggcaat gcctgccata tggtctccca
    46861 tacgttcaag gtctgaacaa gaagacatga tgctaatcac aaatcgaagg tcagacactt
    46921 gtggctgctg caaggctaac aaacgggcac aggtcaattc gatagcgctt tgaccttggt
    46981 tgatagcatg atccttattg ataattagct ttgccatctc cttgtctttg gaggctaagg
    47041 ccagtaaggc ttttgaagct gtttcaagga caagttgccc tagtcctaaa aaggattgtt
    47101 ctaattcatg caattctaag tcaaattgat ttctcatagg tttttccttc cttatccgaa
    47161 ccgtcctgaa atatagtctt ctgtgcgctg atcttttgga ttggtaaaca cgtcaacggt
    47221 atctccaaat tcgcaaattt ctcctgttaa gaaaaaagca gttttatctg aaatacgtga
    47281 agcttgttgc atgttatggg taacaatgat aatcgtataa tcctttttta gttgctgaat
    47341 gaggtcttca atttttaaag tggagatagg gtctaaggct gaagtcggct catccattaa
    47401 cagaatatca ggttctactg ctaaagctcg cgcaatgcaa aggcgttgct gctgaccgcc
    47461 agataaggac atggcactct ttttaagatc atctttgact tcttcccaaa tggctgcccc
    47521 ttttaaagat ttctccacta aggcatctaa ttgttttttg tctcgaatac catgtgtcct
    47581 tggaccataa gccacgttat catagataga catggcaaag ggattaggct gttgaaaaac
    47641 catccctaca cgcttgcgta gctgattaag gttgaatttg ctactataaa tatcttgctc
    47701 atctaagagg acttggcctt caatatggca agaaggaacc aaatcgttca tccgattaag
    47761 ggtttttaga aaagttgatt tgccacaacc agatgggcct atcaaggcag taatctgtct
    47821 ttctggtaat tgaatcgaaa tattttttaa ggcttgaaaa tccccgtaaa ataagtctag
    47881 gtgtctgact gaaaatgttc ccatactagg aagctccttt cacaagtttc cgagataata
    47941 agcttgatag agtatttatc attaaaacag taataatcaa aatcacgccg gtagcatagg
    48001 cttcattgac atgtagcccc tcacttgaca gcatatacat atgtagggct agagaacggc
    48061 ctgaagacat gagactactt ggcgtattgg tagaggtacc taatgtatac atgagggcag
    48121 ctgtttcacc aacgatacgg ccaatagcta gtatcactcc agctaaaata cctggcatgg
    48181 caactggtag aacaattcta aaaacagtcc gtaacttacc tgccccaagt ccataacttg
    48241 cttgacgcat gctatcacta acagataaaa gggcttcttc tgttgagcga ataatgactg
    48301 gcaacaccat gataactgag gttaagattc ctgataacag agagtattga aaacctaaga
    48361 agactacaaa gaagagcatg ccaaacagac caaaaacaat ggaaggaatc ccagacaagg
    48421 tatctgaggc caatcgcatg attttaacac aaagagaatc tttttttgta tattccacaa
    48481 gataaaaacc agcaaaaatc cctatgggca aggctaaaag aagagcacca aaaaccagaa
    48541 taacggtgga aataatcgct ggcataaggg aaatgttctc agaagtataa gtccaagaaa
    48601 agagggatag acttagatga ggtaagcctt tgatgaggat aaaaccaatg attaaaaaga
    48661 gagagccaaa ggttaaagct gaaaaacaat aaacgagaag ttttagcagg tatttactca
    48721 taagatgatt ttcctttcaa gtaggcaaag taggcattaa tcaagagaat aaggaaaaag
    48781 agaactgctg aggttgcaat aagggcttcc ctatgctgac ctgatgcgta agccatttcc
    48841 agaacaatat tggttgttaa ggttctggtt cctgaaaaga gtccacttgg aataatcggc
    48901 tggttgcctg ccaccaaaat aactgccatg gtttcaccta ctgcgcgacc gattcctaaa
    48961 ataactgctg ataaaatacc agatctcgca gctggcaaga tgacactaaa aatactccgt
    49021 tcatgactag ctcctagagc caagctacca gaataatacg ttttgggaac tgttcggata
    49081 gcagattctg acaaactgat aatggttggc aaaatcatta ttcctaatag taacgaagcg
    49141 gttaggacac tcatgccatt tcctaaaaag gttctaatcc aaggcaccaa taattgtagg
    49201 ccgaaaaaac cataaacaat agatggaatg gctgccatca agttgatagc tgattttaag
    49261 aagctataga cgggctttgg acaataataa accataaaca ccgatgtcaa gatgcctgtt
    49321 ggcaccccaa tcacaatcgc tcctaaggta attaataagg aaccaacgat cattggtaaa
    49381 ataccatagc ttgccggaat gttcgttggc gaccaatcac tgcctaataa aaaacgggca
    49441 aagccgtagt tagctatgaa aggtaagcca ttactaaaaa taaagaaaca gattagcaaa
    49501 atagctacaa cagctactgt tgcactcatg aaaaaaattg ccctaaaaac tgcttctttg
    49561 aaggcttgtt ttgtcacatc ttgtcctttc tagtgaagaa agtaagggag atacgacacc
    49621 tccctacttg ccttctttat cttattgtac gatgaaacgt ctgcatctct ttagagattt
    49681 atggagcaaa cattttattt aatcttgtcc caggtggtta atttgccact aaaaacgtcc
    49741 gcaagttcag ccatactgac ttggcttgcc ttattgtcat tattgaccac aacagcaata
    49801 ccgtctaaag caatagcatc atgggtgaga ctcttacctt cttcaggagt taattcccta
    49861 gaaaccatac caatatcagc ggttttctcc ttaacagcgg taatacctgc tgaagaccca
    49921 ttagaggtaa tatcaatcgt aacttctgga ttttcttttt tataagcttc tgctaatttt
    49981 tccattaaag aagatactga agtggaacct acaacagaca acttgcctga taagtgttgg
    50041 cttgtatatt ctgtggtttc ggttttagct tcaataaatt tattatctgt gaccacttgt
    50101 tgaccttgtt tggagtggat aaagctgata aaatcttgac ctagcttgga aagattagaa
    50161 gaccaaacaa tgttgaaggg acgttgaaga gggtattcac catctaaaac tgtgtctcga
    50221 ctagccttga caccatcaat ctctaaagcc ttgacagatt tcgttaaaga tcccaaggag
    50281 atgtagccga tagcattagc attcccttga actgctgaga gaacaccttc tgtactattt
    50341 tgaatcacag ctgttttggc agtgttgtca atttttttat caccgtcttt tttgagaatc
    50401 cctgtgattt ctgtgaaggc accccgtgtt ccagagccat tttctcgtga aatcacctca
    50461 atcgttcctg aagctgactg tttggaagca gctgactgat tgccacaggc aacaagccca
    50521 aatcctgata agccaatggc tgcaagagta agcatttttt tgaatttcat aataatcacc
    50581 tttatctcta tgtatttttc ttgtgtaggc ttactacatt tatagtctaa caagtctttg
    50641 taaaggttta tccctgattc atgtaaagat tgtgtaaaga atcaaaaaaa gccacttttg
    50701 aaaaatggct gctcctaaaa atagctttaa aaattattag tcctgtgcga aagattggtt
    50761 aggaagaaaa atcgtgaagc aactgcctct gccaagctga ctcgtcaccg tgacttggcc
    50821 acctaataat tgactgagtt ctttgacaat ggcaaggcca agaccagtgc caccagtttg
    50881 tctgcttcga cctttattaa ctcggtaaaa acgttcaaaa atacgatcct gctctaattg
    50941 actaatacca atccctgtat ctgatacaga aatcttaatg ccttcgttca ccttttgggt
    51001 cttgacctca atttttcccc cttgttcagt gtaacggatg gcattggata aaagattgag
    51061 taagatttgg gaaagtaatt gactatctga tacgagggtg acatcatctg gcacctgcac
    51121 ctttagctgt aaatccttct tcttgagctg aggttgcaag ctttgagtca aatcctgtac
    51181 aaattctgcc aaagaaaggg tcgtccattg tataggcatt tgttgagcct tagataaggt
    51241 aagaagatgc tcaacaatat gctcaagacg caagctttct ttgtaaataa tgtctagaaa
    51301 gtcatccttg agcgcttctt cttcagctga catcccctta atggtttcag caaagccctt
    51361 aattgaagta actggtgtcc tcaattcatg ggaggcattt gagacaaagg ctaaatttaa
    51421 cttttcataa gttctaatcg ttgttaaatc atatagcaag acgagcacag cttccacaga
    51481 ttgggtgggg ctaaaaacgg gaactgctgt cacttctaaa atcaagtcac cctcatgaaa
    51541 cccacttact tcttgtttta accttgtttt ttgatcaaag gcttggtgaa ctaaattccg
    51601 aatatccatc cgtttgaggt catcaagtga acttatgtcg ccgtccacat cgggaaaata
    51661 atgaggcaga gagcgactgg ataataacat ctgaccttga gcggaaacta aaaacgtccc
    51721 catggttagg tgcgacagaa gaacctccat tgtttcggct aggtccttgt attgctgatc
    51781 ctgttgggag actttggttt ttaggccaga cacatactta gccaaagact ttaagtcttc
    51841 ttgccctttt tctaaaaagt attcactact ggtcaagaga ggttggtgca aggtctcaaa
    51901 agcaacttcc catttccaaa ggcaaaagag ccagtagcca cctagtccca aagaaagggc
    51961 tagaagaaag agaccgatgc ctttactgat ccaagttaat gccattcctg caatcagaat
    52021 gaggctaaca cttagattga ctagccaaaa ttgaaggtag cgtttcatct ataactcctt
    52081 gaacttataa ccataacccc gaatggttcg aataaattga ggggctttag gattgtcttc
    52141 aattttttcc ctcaacttac caatatgaac gtccaccaaa cgtgtttcct gcccaaagtc
    52201 atatccccag atacgttcca aaagacgctc tctagtcagt gtcatgttgg gatgtttcat
    52261 aagatagagc aagagttcaa attcttttgg ggtcaaactc agtaacttat tcgccttgta
    52321 gacctcatga cgctcagggt atactttcaa ggtcccaaat agccaagaat cgtcagcaat
    52381 attatctgaa tcatctcctt cttgttctcc tttagttcgc ctgaggacag ccttgacacg
    52441 tgccagcaat tctctagggc taaaaggctt ggtcaggtag tcatcagccc ctaattccaa
    52501 ggccaaaacc ttatcaaatt catcactttt cgcagaaacc atcataattg gagttttgat
    52561 gcctttggct ctcagccgct tacaaacttc tatgccatct aattgtggta acatgatatc
    52621 aagcaagata aaatcaaagg gttctgtttc tgccaaagct aaggccttcc gtccatttgt
    52681 taccaattga gtagaaaagc cttccttact taaatggtag tcaagcaatc tcagaatgtg
    52741 ttcttcatca tccactaata agacttgttt tgtcatctat tatctcctat tggtaacatt
    52801 ataacacaat tatcagaaat cctaacattg ctaaatcaga ttaaatttgc ttatcaagac
    52861 tagtatctgg tcaaatgctc aatcatctcc ttgtgctctg gataggtcgc cagtagatct
    52921 gccctttcaa ataattcaaa atcctcaaat tcaaaaccag gagcaacaag acaagaaacc
    52981 agagcataat ccttatcaac tgttgatccc caaatagtgc ccttaggaac acagtagtga
    53041 agttgttgcc ctttggatat gtccaggcct aaagtgactg cttcgtagtg accatctgct
    53101 gtaatcatgt gaacagtaag tggggatcct gcatgaaaat accagatttc atctgctgtc
    53161 aatcggtgaa aatgtgaagg attcgtttct tctaataaga aataaatact ggtataaagc
    53221 gcccttcctt taccagcaag gtttatagtg tctgaagctt tttttgtttg tctaaaatag
    53281 ccaccttcaa catggggagc taactctaga gttcttatca agtcttcttt atccgtcgga
    53341 gccaatgggt tgaagtaact cttgttcaaa gtagttttac gatttcaaga actcctctca
    53401 gttctgagga cacggtaatg attgatgcga cggaagtaaa aatcaatcgc cctaaaaaag
    53461 aattagcgaa tgattctggt aaaaagaaat gccacgctat gaaggctcaa gcgattgtca
    53521 caagtcaagg gagaattgtt tctttggata tcactgtgaa ctattgtcat gatatgaagt
    53581 tgttcaaaat gagtcgcaga aatatcggac aagctggtaa aatcttggct gacagtggtt
    53641 atcaagggct tatgaagata tatcctcaag cacaaactcc acgtaaatcc agcaaactca
    53701 agccgctaac agctgaagat aaagcctgta accatgcact atctaaggag agaagcaagg
    53761 ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaact tatcgaaatc
    53821 atcgtaaacg cttcggatta cgaatgaatt tgattgctgg cattatcaat catgaactag
    53881 gattctagtt ttgcaggaag tctattattt ggttaggtga attagtgaag cgtttaggca
    53941 agtgtctctg gttacgacgt aaagaagcat aaatcgataa tatttatgtt tctttactag
    54001 tgaaacgcct agccaaatta ccatagttac gacgtcatgg cctctaaatc gattatattt
    54061 aggggtcatg actagtgaag cagttagcta gttcgcatat aagcggctag cgtctaacaa
    54121 ttaggaactt tagttccaat aactttaaga ttacgacgtt ttaggacata aatcgatcat
    54181 atttatgtcc taaaactagt gaagcgccta gccaaagtcc gaataggatt tggcgttagt
    54241 tacttagatt gctttgcaat caagtaactt tggcgattta catcttctct ggcgcttcta
    54301 ctccaagcaa gcgaagggct tctttgagaa cgactgcggt tgcgtagctg agggctagac
    54361 ggctgtcgcg ttctgggctt tcatccaaga tacgtgtatg tgcatagtat ttgttaaagg
    54421 attgagctag gctaattgca aatttagcaa tgatagaagg ttcaaagtta tctgccgcac
    54481 ggttgataat acgtgggaag tcttgaatga gtttaatgat ttcccagctt tcagtatcat
    54541 tcaagctata gttgccagct gtttctggtt tgaaatcggc tttgcgtaag atagattgga
    54601 tacgagcgta ggcatattga acgtaaggtc cagtttcacc ctcgaaggat accatagcct
    54661 ctaggtcgaa gtcgtatcca tttgtacggt cggttttgag gtcatagaat ttaatggctc
    54721 caaccccaac agcatgtgct acttggtctt tgttttctag ttcaggattt ttagcctcga
    54781 tttggacctt ggcacggcta acagcctctg caacagtagg ctctagcaag atgacattcc
    54841 ctttacgagt agagagtttc ttcccttctt ttgtaaccaa accaaaagga acgtgagtaa
    54901 tgtcgtcact ccagtcgtag cccatctctt gcaagacagc tttgagctgt ttaaagtggg
    54961 cagattgttc ttgaccaacg acatagatag atttagcaaa ttggtattcg tttttacggt
    55021 aaagggctgc agccaagtca cgtgtgatat agagagttgc accatcagat ttcttgatga
    55081 gagctggatg ttcaattccg tatttctcaa gattgacaac ttgggcacct tctgattcaa
    55141 gaagtagtcc tttttcagaa agaatgtcta caactgcatc catcttatca ttgtagaagg
    55201 cttctccgtt atagctgtca aattcaacct tcaattcatt gtaaaggcgg ttaaattcca
    55261 ctaaactttc atcgcggaac cattgccaaa gagcgagagc ttcctcatct ccattttcaa
    55321 gtttacggaa ccattcgcgc gcttcttcat ccaagctagg gtcattttca gcttcagcgt
    55381 tgatgcggac atagagttta aggagttcat cgattggatg agcttttaca gcttcttcgt
    55441 cgccccattt tttgtaggca acaatcaaca tcccaaattg tttaccccag tctcccaaat
    55501 ggttgacctt gaccgtttga taaccgattt tttggaaaat atgtgacaag ctatctccga
    55561 taacagttga acgcaggtgg ccaatagaaa atggtttagc gatattcgga ctagacatgt
    55621 cgataacaac attttcttgt ttaccaatat tttggtcagc atagtgttct ttttcagtgg
    55681 taacagcttg caatacttga gcagaaatgg cagatttatc aaggaaaaag ttaacgtaag
    55741 gtcctgttgc gacaactttt tcaaaggctt ggctgttcat tttttcagcc agttcagccg
    55801 caatcatttg tggtgcttta cgttcgactt tggcaagaga aaaagcaggg aaagcgatgt
    55861 cacccatttc tgagttttta ggggtttcca gtaactttaa aatagcctct tggtccaggc
    55921 tatcaatgat gctagccaat tcgctagcaa tcaattcttt tgtattcatt aagagctcct
    55981 ttttggactt ttctactatt ttatcacaat tttaaagaaa gaagaaaaaa tttttgaaat
    56041 ctcctgtttt tttggtataa tatggttata aatatagtta taaatatgca cgcaagagga
    56101 ttttatgaga aaaagagatc gtcatcagtt aataaaaaaa atgattactg aggagaaatt
    56161 aagtacacaa aaagaaattc aagatcggtt ggaggcgcac aatgtttgtg tgacgcagac
    56221 aaccttgtct cgtgatttgc gcgaaatcgg cttgaccaag gtcaagaaaa atgatatggt
    56281 gtattatgta ctagtaaatg agacagaaaa gattgatttg gtggaatttt tgtctcatca
    56341 tttagaaggt gttgcaagag cagagtttac cttggtgctt cataccaaat tgggagaagc
    56401 ctctgttttg gcaaatattg tagatgtaaa caaggatgaa tggattttag gaacagttgc
    56461 tggtgccaat accttattgg ttatttgtcg agatcagcac gttgccaaac tcatggaaga
    56521 tcgtttgcta gatttgatga aagataagta aggtcttggg agttgctctc aagacttatt
    56581 tttgaaaagg agagacagaa aatggcgata gaaaagctat cacccggcat gcaacagtat
    56641 gtggatatta aaaagcaata tccagatgct tttttactct ttcggatggg tgatttttat
    56701 gaattatttt atgaggatgc ggtcaatgct gcgcagattc tggaaatttc cttaacgagt
    56761 cgcaacaaga atgccgacaa tccgatccct atggcgggtg ttccctatca ttctgcccaa
    56821 cagtatatcg atgtcttgat tgagcagggt tataaggtgg ctatcgcaga gcagatggaa
    56881 gatcctaaac aagcagttgg ggttgttaaa cgagaggttg ttcaggtcat tacgccaggg
    56941 acagtggtcg atagcagtaa gccggacagt cagaataatt ttttggttgc catagaccgc
    57001 gaaggcaatc aatttggtct agcttatatg gatttggtga cgggtgactt ttatgtgaca
    57061 ggtcttttgg atttcacgct ggtttgtggg gaaatccgta acctcaaggc tcgagaagtg
    57121 gtgttgggtt atgacttgtc tgaggaagaa gaacaaatcc tcagccgcca gatgaatctg
    57181 gtactctctt atgaaaaaga aagctttgaa gaccttcatt tattggattt gcgattggca
    57241 acggtggagc aaacggcatc tagtaagctg ctccagtatg ttcatcggac tcagatgagg
    57301 gaattgaacc acctcaaacc tgttatccgc tacgaaatta aggatttctt gcagatggat
    57361 tatgcgacca aggctagtct ggatttggtt gagaatgctc gctcaggtaa gaaacaaggc
    57421 agtcttttct ggcttttgga tgaaaccaaa acggctatgg ggatgcgtct cttgcgttct
    57481 tggattcatc gccccttgat tgataaggaa cgaatcgtcc aacgtcaaga agtggtgcag
    57541 gtctttctcg accatttctt tgagcgtagt gacttgacag acagtctcaa gggtgtttat
    57601 gacattgagc gcttggctag tcgtgtttct tttggcaaaa ccaatccaaa ggatctcttg
    57661 cagttggcga ctaccttgtc tagtgtgcca cggattcgtg cgattttaga agggatggag
    57721 caacctgctc tagcctatct cattgcacaa ctggatgcaa tccctgagtt ggagagtttg
    57781 attagcgcag cgattgctcc tgaagctcct catgtgatta cagatggggg aattatccgg
    57841 actggatttg atgagacttt agacaagtat cgttgcgttc tcagagaagg gactagctgg
    57901 attgctgaga ttgaggctaa ggagcgagaa aactctggta tcagcacgct caagattgac
    57961 tacaataaaa aggatggcta ctattttcat gtgaccaatt cgcaactggg aaatgtgcca
    58021 gcccactttt tccgcaaggc gacgctgaaa aactcagaac gctttggaac cgaagaatta
    58081 gcccgtatcg agggagatat gcttgaggcg cgtgaggagt cagccaacct cgaatacgaa
    58141 atatttatgc gcattcgtga agaggtcggc aagtacatcc agcgtttaca agctctagcc
    58201 caaggaattg cgacggttga tgtcttacag agtctggcgg ttgtggctga aacccagtat
    58261 ttgattcgac ctgagtttgg tgacgattca caaattgata ttcggaaagg gcgccatgct
    58321 gtcgttgaaa aggttatggg ggctcagacc tatattccaa atacgattca gatggcagaa
    58381 gataccagta ttcaactgat tacagggcca aacatgagtg ggaagtctac ctatatgcgt
    58441 cagttagcca tgacggcggt tatggcccag ctgggttcct atgttcctgc tgaaagcgcc
    58501 catttaccga tttttgatgc gatttttacc cgtatcggag cagcagatga cttggtttcg
    58561 ggtcagtcaa cctttatggt ggagatgatg gaggccaata atgccatttc gcatgcgacc
    58621 aagaactctc tcattctctt tgatgaattg ggacgtggaa ctgcaactta tgacgggatg
    58681 gctcttgctc agtccatcat cgaatatatc catgagcaca tcggagctaa gaccctcttt
    58741 gcgacccact accatgagtt gactagtctg gagtctagtt tacaacactt ggtcaatgtc
    58801 cacgtggcaa ctttggagca ggatgggcag gtcaccttcc ttcacaagat tgaaccggga
    58861 ccagctgata aatcctacgg tatccatgtt gccaagattg ctggcttgcc agcagacctt
    58921 ttagcaaggg cggataagat tttgactcag ctagagaatc aaggaacaga gagtcctcct
    58981 cccatgagac aaactagtgc tgtcactgaa cagatttcac tctttgatag ggcagaagag
    59041 catcctatcc tagcagaatt agctaaactg gatgtgtata atatgacacc tatgcaggtt
    59101 atgaatgtct tagtagagtt aaaacagaaa ctataaaacc aagactcact agttaatcta
    59161 gctgtatcaa ggagacttct ttgacaattc tccacttttt tgctagaata acatcacaca
    59221 aacagaatga aaaggagctg acgcattgtc gctccctttt gtctattttt taaggagaaa
    59281 gtatgctgat tcagaaaata aaaacctaca agtggcaggc cctggcttcg ctcctgatga
    59341 caggcttgat ggttgctagt tcacttctgc aaccgcgtta tctgcaggaa gtcttaggcg
    59401 ccctccttac tgggaaatat gaagctattt atagtatcgg ggcttggttg attggtgtgg
    59461 ccgtagtcgg tctagttgct ggtggactca atgttgtcct cgcagcctat attgcccaag
    59521 gagtttcatc cgaccttcgg gaggatgcct tccgtaaaat tcaaaccttt tcttatgctg
    59581 atattgaaca atttaatgcg ggaaatctag tcgttcgaat gacaaatgat atcaaccaga
    59641 ttcagaacgt tgtcatgatg accttccaaa ttcttttcag acttcccctc ttgttcatcg
    59701 gttcgtttat cctagcggtt caaaccttac cttctctgtg gtgggtgatt gttctcatgg
    59761 tagtcttgat ttttggtttg actgctgtca tgatgggaat gatggggcct cgttttgcta
    59821 aatttcaaac ccttcttgag cgcatcaatg ccattgccaa ggaaaattta cgtggcgttc
    59881 gtgtggtcaa gtcctttgtc caagaaaaag agcaatttgc taagtttaca gaggtctcaa
    59941 acgagcttct tggtcaaaac ctttacattg gttatgcctt ttcagtagtg gaacccttta
    60001 tgatgttggt tggttacggg gcggtcttcc tctctatttg gctggtcgcg ggaatggttc
    60061 agtcggatcc gtctgttgtt ggttccatcg cttcttttgt taattaccta agccagatta
    60121 tctttaccat tgttatggtt ggatttttgg gaaattctgt cagccgtgcc atgatttcca
    60181 tgcgtcgtat tcgagaaatt cttgacgcag agccagctat gaccttcaag gatatcccag
    60241 atgaagagtt ggttggaagt cttagctttg aaaatgtgac ctttacctat ccaatggaca
    60301 aggaaccgat gctgaaagat gtgagcttta ctattgaacc tggtcaaatg gttggtgtag
    60361 ttggagcgac tggtgcagga aagtcaacct tggctcaatt gattccacgt ctctttgatc
    60421 cacaggacgg ggccattaaa atcggtggca aggatattcg agaagtgagt gaaggaaccc
    60481 tgcgtaaaac agtttccatc gttctccaac gtgccattct ttttagtgga acgattgcag
    60541 ataacttgag acaggggaag ggaaatgcta ctctatttga aatggagcgc gcagccaata
    60601 ttgcccaggc tagtgaattc attcatcgta tggagaaaac ctttgaaagt ccagttgaag
    60661 aacggggaac caatttctct ggtggacaaa aacaaaggat gtcgattgcg cgtgggattg
    60721 tcagcaatcc acgtattctg atttttgacg attcgacctc agccttggat gccaaatcag
    60781 agcgcttggt gcaagaagct ttgaataagg acttgaaggg gacgacaacc attattattg
    60841 ctcaaaaaat tagctcggtt gtccatgcag acaagatctt ggttctaaat caaggacgat
    60901 tgattggtca aggcacgcat gcagacttgg ttgccaacaa tgccgtttac cgtgaaatct
    60961 atgaaacaca gaaatgaaag acaaactata agaaaagtca atagttttat ctaaactatt
    61021 tcttatttca atttgatgat ttggcgatga ttttagagca cggcaaaaag cccttgaaaa
    61081 agtccatttt ttcaaaggta atcctgtgtt gatttcagaa attacatcac tttttgttcg
    61141 tcaaatggca gctctttttt aggatataaa acagggttcg gataagtttt tttgcaaggt
    61201 ggatgatggc tacattgtaa tgttttcctt gttctaactt agtcttaaaa gcaggtgaaa
    61261 agtgagggca tgctttggca gcttgtatga gtacctaccg cagatgaggg gaaccccgtt
    61321 tgaccattct tccagctaaa tcaatctgac ctgactgata aatagaagaa tccagtccag
    61381 cgaaagcttg taattgagca ggattatcaa aggcatgaat atttcgaatc tcggctaaaa
    61441 tgaccgcccc taaacgattc tcaatcccag taaccgtcgt gatgaccgag tttaactcag
    61501 ccatcaagtc attgacacat ttttccgcct tgtcaatgag cctcttgtaa tgtttgatgt
    61561 tttcattaca cgagataaaa cgtctatgcg ttatcaaact cattaccaat taaaacaaat
    61621 gtggttagat cctttcggaa attgtcaagc gattggagga aatgaactaa tccacagcgg
    61681 cttattccaa gtataccact tgggctttgg cagtagctaa ctgcgctaaa tataatataa
    61741 ggaggagtaa aatgaagaca gttcaatttt tttggcatta ttttaaggtc tacaagttct
    61801 catttgtagt tgtcatcctg atgattgttc tggcgacttt tgcccaagcc ctctttccag
    61861 tcttttctgg acaagcggtg acgcagctag ccaatttagt tcaagcttat caaaatggca
    61921 atccagaact tgtatggcaa agcctatcag gaatcatggt caatcttggc ctgctggttt
    61981 tggttctatt tatctctagt gtaatataca tgtgtctcat gacgcgcgtg attgcagaat
    62041 cgaccaacga gatgcgcaaa ggtctctttg gtaagcttgc tcagttgacg gtttctttct
    62101 ttgaccgtcg acaagatggc gatatcctgt ctcattttac cagtgatttg gataatatcc
    62161 tccaagcctt taacgaaagc ttgattcagg tcatgagcaa tattgtttta tacattggtc
    62221 tgattcttgt catgttttcg agaaatgtga cgctggctct catcaccatt gccagcaccc
    62281 cattggcttt ccttatgctg attttcatcg tgaaaatggc acgtaaatac accaacctcc
    62341 agcagaaaga ggtagggaag ctcaacgcct atatggatga gagcatctca ggccaaaaag
    62401 ccgtgattgt gcaaggaatt caagaggata tgatggcagg atttcttgaa caaaatgagc
    62461 gcgtgcgcaa ggcaaccttt aaaggaagaa tgttctcagg aattcttttc cctgtcatga
    62521 atgggatgag cctgattaat acagccatcg tcatctttgc tggttcggct gtacttttga
    62581 atgataagtc tattgaaaca agtacagccc taggtttgat tgttatgttt gcacaatttt
    62641 cacagcagta ctaccagcct attatccaag ttgcagcgag ttggggaagc cttcagttgg
    62701 cctttactgg agctgaacga attcaggaaa tgtttgatgc agaggaggaa atccgacctg
    62761 aaaaggctcc aaccttcact aagttgcaag aaagtgttga aatcagtcat atcgattttt
    62821 catacttgcc tgataaacct attttgaaag atgtcagcat ttctgcccct aaaggccaga
    62881 tgacagcagt tgttgggccg acaggttcag gaaaaacgac tattatgaac ctcatcaatc
    62941 gcttttatga tgttgatgct ggtggtattt attttgatgg taaagacatt cgtggctatg
    63001 acttagatag tcttagaagc aaggtgggaa ttgtattgca agattcggtc ttgtttagcg
    63061 gaacgattcg agacaatatc cgatttggtg tgccagatgc tagtcaggaa atggttgagg
    63121 tagcagcaaa agcaacccac attcacgact atatcgaaag tttgcctgat aagtacgata
    63181 ctcttattga tgatgaccag agcatctttt caacagggca gaagcaattg atttcaatcg
    63241 ctcgaaccct gatgacagat ccagaagttc tcattctcga tgaagcaact tcaaacgtag
    63301 atacggtgac agaaagcaag attcagcatg ccatggaggt ggttgtagca ggtagaacta
    63361 gtttcgtcat tgcccaccgc ttgaaaacca ttctcaatgc agatcagatt attgtcctta
    63421 aagatggaga agtcattgaa cgtggtaacc accatgaact tttgaagcta ggtggctttt
    63481 attcagaact ctatcacaat caatttgttt tcgaataaga aagaagttgt cctatgtggg
    63541 cagctttttc ttgtccataa aaaatgttta tcacagcctt aaaaaaaaca tattagacga
    63601 aagtcatttt gagtgatatg ataggactat cgttagcatt cgaaaggaga ggcatcatgg
    63661 ctagaacggt tgtaggagtt gctgcaaatc tatgtcccgt agacgcagaa ggcaaaatca
    63721 ttcattcatc tgtatcttgt agattcgcag agatcattcg tcaagtcggt ggtctccctt
    63781 tagtcattcc tgttggtgat gagtcagttg tacgtgatta tgtggaaatg attgacaaac
    63841 tcattttgac aggaggccaa aatgttcatc ctcagtttta tggagagaaa aagaccgtcg
    63901 agagcgatga ttacaatctg gtccgtgacg aatttgaatt ggcactcttg aaggaagcgc
    63961 ttcgtcagaa taaaccaatt atggcaatct gtcgcggtgt ccaacttgtc aatgttgcct
    64021 ttggtggaac cctcaatcaa gaaatcgaag gtcactggca aggactacct ttcgggacat
    64081 ctcactctat tgagacagta gaaggaagcg tggtggctaa gctctttggg aaagaaagtc
    64141 aggtcaactc agtccatcgt caaagcatta aagatttggc acctaatttc cgtgtaactg
    64201 ctattgattc aagagaccaa actattgaag cgattgagtc tatcgacgag caccgcatta
    64261 tcggtttaca gtggcatcca gagtttctgg ttaatgaaga agatggcaat ttagaattat
    64321 ttgagtattt attgaatgaa ctgtaacgat tgcaacatct ggtcgttctt tcttttattt
    64381 tttcaaaatt tttagaatgt ggtattttac gcaaacgttt gaattctgat aaaaattgga
    64441 gaaattcgac aagaaaactt gaaaaaaacg aaggtaagcg ttatgataga aaagaagaaa
    64501 tattggagga agaacatgtc acatattaaa tttgattatt caaaagtttt agacaaattt
    64561 gttgcaccac atgaagtgga atacatgcaa tcacaagtaa cagcagcaga tgaattgatc
    64621 cgtaaaggaa ctggtgctgg tagcgacttc ttgggatggt tggaccttcc tgaaaaatac
    64681 gatcgcgaag aatttgaccg catcttgaaa gctgctgagc aaatcaagtc agacagcgat
    64741 gttttggttg tgatcggtat tggtggatct taccttggtg caaaagcagc aatcgacttc
    64801 ttgaatcacc attttgctaa cttgcaaaca aaagaagaac gcaaagctcc acaaatcctt
    64861 tacgcaggaa actcaatctc atctacttac cttgctgact tggtagagta tgttgcagac
    64921 aaagacttct cagtaaacgt aatttctaaa tcaggtacaa caactgaacc agcgattgct
    64981 ttccgtgtct ttaaagaact cttggttaag aaatacggtc aagaagaagc taacaaacgt
    65041 atctatgcaa caactgaccg ccaaaagggt gctgttaagg ttgaagcaga cgctaacggt
    65101 tgggaaacat ttgttgttcc agatgatatc ggtggacgct tctcagtatt gacagccgtt
    65161 ggtttgcttc caatcgcagc atcaggagct gacatcaaag ctcttatgga aggtgcgaat
    65221 gcagctcgca aagactacac ttcagacaaa atctctgaaa acgaagctta ccaatacgca
    65281 gctgttcgta acatccttta tcgtaaaggc tatgcaactg agatcttggt aaactatgag
    65341 ccatcacttc aatacttctc agaatggtgg aaacaattgg ctggtgaatc agaaggaaaa
    65401 gacaaaaaag gtatctaccc aacttcagcc aacttctcaa ctgacttgca ctcacttggt
    65461 caatttatcc aagaaggaac tcgtatcatg tttgaaacag ttgtccgtgt tgacaaacct
    65521 cgtaaaaacg tgcttattcc tactttggaa gaagaccttg acggacttgg ttaccttcaa
    65581 ggaaaagacg ttgactttgt aaacaaaaaa gcaactgacg gtgttcttct tgcccacaca
    65641 gatggtgatg taccaaacat gtatgtgact cttccagagc aagacgcttt cactcttggt
    65701 tacactatct acttcttcga attggcaatt gccctttcag gttacttgaa tgctatcaac
    65761 ccatttgacc aaccaggtgt tgaagcttat aaacgtaaca tgtttgccct tcttggaaaa
    65821 ccaggatttg aagaattgag caaagaactt aacgcacgtc tataatagaa gaaaagagtg
    65881 gtttgcccac tctttttact ctctttatcc atagaaattg gactcagcca agacttgtga
    65941 tataatatag aaagcaaaaa ggcagacgcc tagataatag gagaaactat gtcaaaagat
    66001 atccgcgtac gttacgcacc aagtccaaca ggactactac acatcggaaa tgcccgtaca
    66061 gcattgttta actacttgta tgcgcgccat catggtggaa catttctcat ccgtatcgaa
    66121 gatactgacc gtaaacgcca tgtcgaggat ggtgaacgtt cacaacttga aaaccttcgc
    66181 tggttaggca tggattggga tgaaagtcca gaatcacatg agaattatcg ccagtctgag
    66241 cgtttggact tgtatcaaaa atacattgac caactattag ctgaaggaaa agcctataaa
    66301 tcttacgtta cagaagaaga gttggcagct gaacgtgaac gtcaagaagc tgctggtgaa
    66361 acacctcgat atatcaacga ataccttggt atgagtgaag aggaaaaagc ggcttatatc
    66421 gcagaacgtg aagcagctgg tatcatacca acagttcgtt tggctgtcaa tgagtcaggt
    66481 atctacaagt ggcatgatat ggtcaaaggt gatatcgaat ttgaaggtgg caatatcggc
    66541 ggtgactggg ttatccaaaa gaaagacggt tacccaactt acaactttgc cgttgttatc
    66601 gatgaccacg atatgcaaat ctctcatgtt atccgtggag atgaccatat tgctaataca
    66661 ccaaaacagc ttatggtcta tgaagctctt ggttgggaag ctccagagtt tggtcacatg
    66721 accttgatta tcaactctga gactggtaag aagttatcta aacgtgatac taatacactt
    66781 caatttatcg aagattaccg aaagaaaggt taccttccag aagcagtctt taactttatt
    66841 gctcttcttg gttggaaccc aggtggtgaa gatgagattt tctctcgtga agaactcatt
    66901 aaactttttg atgaaaaccg cctcagcaag tcaccagcag cctttgatca gaaaaaacta
    66961 gactggatga gcaatgatta tatcaagaat gcagaccttg aaaccatctt tgaaatggca
    67021 aaaccattct tagaggaagc aggccgtttg actgacaagg ctgaaaaatt agttgagctc
    67081 tataaaccac aaatgaaatc agtagatgag attatcccat tgacagatct tttcttctca
    67141 gatttcccag aattgacaga agcagagcgc gaagtcatga cgggtgaaac agttccaaca
    67201 gttcttgaag cattcaaagc aaaacttgaa gcgatgacag atgatgaatt tgtgacagaa
    67261 aatatcttcc cgcaaattaa agcagtccaa aaagaaacag gtattaaagg gaaaaatctt
    67321 ttcatgccta ttcgtatcgc agtttcaggc gaaatgcatg ggccagaatt accagataca
    67381 attttcttgc ttggacgtga aaaatcaatt cagcatatcg aaaacattct aaaagaaatc
    67441 tctaaataaa gaggatacaa taatggacat ctgggaaaag atgtacgaag aagcacagaa
    67501 actatacaat ccacatgaag tatcagactt tgtttatgcc aatcatgttg tagctgcagt
    67561 agaagcagga gatggacaaa tatttacagg attctgtatg gagggaacct gtggtgtttt
    67621 ccatctctgc gcagaacggg cggccctctt caatatgtac caattttcag gacaaactaa
    67681 ggttaagaaa gtattagcct ttcgagacaa accaccttat ggtggaagtt cagccatgcc
    67741 ttgcggtgct tgtagagaat tccttttaga gcttaatgct gaaaataaag atgcagaatt
    67801 catgatggac tataatataa gaaaaacagt taaagtcgca gaactaatcc cttattggtg
    67861 gggaaaagaa cgtgcttcta agtttaatga gcgatagaag agtcagtata attctggctc
    67921 tttttactat aag
//
LOCUS       DAVKMO010000005        66326 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVKMO010000005 DAVKMO010000000
VERSION     DAVKMO010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 66326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66326
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.005"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..261)
                     /locus_tag="VW361_000349"
     CDS             complement(<1..261)
                     /locus_tag="VW361_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9743477.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNRKIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSS"
     gene            968..2443
                     /locus_tag="VW361_000350"
     CDS             968..2443
                     /locus_tag="VW361_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU9743478.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(2409..3124)
                     /locus_tag="VW361_000351"
                     /pseudo
     CDS             complement(2409..3124)
                     /locus_tag="VW361_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3380..4240
                     /gene="speE"
                     /locus_tag="VW361_000352"
     CDS             3380..4240
                     /gene="speE"
                     /locus_tag="VW361_000352"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU9743479.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            4237..5496
                     /locus_tag="VW361_000353"
     CDS             4237..5496
                     /locus_tag="VW361_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU9743480.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            5496..6623
                     /gene="nspC"
                     /locus_tag="VW361_000354"
     CDS             5496..6623
                     /gene="nspC"
                     /locus_tag="VW361_000354"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU9743481.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            6620..7705
                     /gene="aguA"
                     /locus_tag="VW361_000355"
     CDS             6620..7705
                     /gene="aguA"
                     /locus_tag="VW361_000355"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU9743482.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            7715..8590
                     /gene="aguB"
                     /locus_tag="VW361_000356"
     CDS             7715..8590
                     /gene="aguB"
                     /locus_tag="VW361_000356"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU9743483.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(8771..9580)
                     /locus_tag="VW361_000357"
     CDS             complement(8771..9580)
                     /locus_tag="VW361_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9743484.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            9853..10074
                     /locus_tag="VW361_000358"
     CDS             9853..10074
                     /locus_tag="VW361_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743485.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWQMEPVLTMP
                     VHGFCPRGTDDLGYIGGGNHLCKGSAARF"
     gene            10128..10799
                     /locus_tag="VW361_000359"
     CDS             10128..10799
                     /locus_tag="VW361_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9743486.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTTLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(10851..11039)
                     /locus_tag="VW361_000360"
                     /pseudo
     CDS             complement(10851..11039)
                     /locus_tag="VW361_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11032..11940
                     /locus_tag="VW361_000361"
     CDS             11032..11940
                     /locus_tag="VW361_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9743487.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKSQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLREGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11937..12398
                     /locus_tag="VW361_000362"
     CDS             11937..12398
                     /locus_tag="VW361_000362"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU9743488.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            12388..13275
                     /locus_tag="VW361_000363"
     CDS             12388..13275
                     /locus_tag="VW361_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9743489.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            13278..15161
                     /gene="cbpE"
                     /locus_tag="VW361_000364"
                     /gene_synonym="pce"
     CDS             13278..15161
                     /gene="cbpE"
                     /locus_tag="VW361_000364"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU9743490.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIELYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            15241..16371
                     /locus_tag="VW361_000365"
     CDS             15241..16371
                     /locus_tag="VW361_000365"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU9743491.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            16381..17643
                     /locus_tag="VW361_000366"
     CDS             16381..17643
                     /locus_tag="VW361_000366"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU9743492.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVAFPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            17647..18444
                     /gene="proC"
                     /locus_tag="VW361_000367"
     CDS             17647..18444
                     /gene="proC"
                     /locus_tag="VW361_000367"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU9743493.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            18664..19302
                     /locus_tag="VW361_000368"
     CDS             18664..19302
                     /locus_tag="VW361_000368"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU9743494.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVEVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            19299..20189
                     /locus_tag="VW361_000369"
     CDS             19299..20189
                     /locus_tag="VW361_000369"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU9743495.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQVNVSFQNAMEYLVLKEI"
     gene            20229..20546
                     /gene="yabA"
                     /locus_tag="VW361_000370"
     CDS             20229..20546
                     /gene="yabA"
                     /locus_tag="VW361_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU9743496.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            20549..21427
                     /gene="rsmI"
                     /locus_tag="VW361_000371"
     CDS             20549..21427
                     /gene="rsmI"
                     /locus_tag="VW361_000371"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU9743497.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASKGVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEENQEND"
     gene            21614..22948
                     /gene="trmFO"
                     /locus_tag="VW361_000372"
     CDS             21614..22948
                     /gene="trmFO"
                     /locus_tag="VW361_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU9743498.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            23032..23769
                     /locus_tag="VW361_000373"
     CDS             23032..23769
                     /locus_tag="VW361_000373"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU9743499.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            23778..24335
                     /gene="frr"
                     /locus_tag="VW361_000374"
     CDS             23778..24335
                     /gene="frr"
                     /locus_tag="VW361_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU9743500.1"
                     /translation="MANIIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            24395..25249
                     /gene="cvfB"
                     /locus_tag="VW361_000375"
     CDS             24395..25249
                     /gene="cvfB"
                     /locus_tag="VW361_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU9743501.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGCVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            25258..25473
                     /locus_tag="VW361_000376"
     CDS             25258..25473
                     /locus_tag="VW361_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU9743502.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            25559..26527
                     /locus_tag="VW361_000377"
     CDS             25559..26527
                     /locus_tag="VW361_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU9743503.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(26505..26684)
                     /locus_tag="VW361_000378"
     CDS             complement(26505..26684)
                     /locus_tag="VW361_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743504.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            26720..27220
                     /locus_tag="VW361_000379"
     CDS             26720..27220
                     /locus_tag="VW361_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9743505.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            27223..27483
                     /locus_tag="VW361_000380"
                     /pseudo
     CDS             27223..27483
                     /locus_tag="VW361_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(27850..28176)
                     /locus_tag="VW361_000381"
     CDS             complement(27850..28176)
                     /locus_tag="VW361_000381"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743506.1"
                     /translation="MVDVAVDQGGLIETADRVTTHDEPVYEKHGVLHYAVANIPGAVT
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(28122..28535)
                     /locus_tag="VW361_000382"
     CDS             complement(28122..28535)
                     /locus_tag="VW361_000382"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU9743507.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGDGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASVRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            complement(28536..28961)
                     /locus_tag="VW361_000383"
     CDS             complement(28536..28961)
                     /locus_tag="VW361_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU9743508.1"
                     /translation="MLIGIPKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSG
                     FTDADYQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDDLLLFTYLHMAAAPEL
                     ADAMLAAKTTGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            29138..29707
                     /locus_tag="VW361_000384"
     CDS             29138..29707
                     /locus_tag="VW361_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9743509.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGKFIGTIDLHKIDPVLKKVAIGYI
                     INQTYWNQGLTTETNRAVIELAFEKIGMNKLVALYDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            29775..30425
                     /locus_tag="VW361_000385"
     CDS             29775..30425
                     /locus_tag="VW361_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEU9743510.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            30409..32649
                     /locus_tag="VW361_000386"
     CDS             30409..32649
                     /locus_tag="VW361_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU9743511.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLQLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVVKIDQLILTNTDKEHVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQVTQTKVRSMTVGEYLPIFGSQLEVLSPRE
                     IGYGGHEDSLVLYGKLLNNHFLFIGNLEEKGEKDLLKYYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            32828..33016
                     /locus_tag="VW361_000387"
     CDS             32828..33016
                     /locus_tag="VW361_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743512.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            33048..33635
                     /locus_tag="VW361_000388"
     CDS             33048..33635
                     /locus_tag="VW361_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743513.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            33639..34820
                     /locus_tag="VW361_000389"
     CDS             33639..34820
                     /locus_tag="VW361_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743514.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LRVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIERWGSSRKKEVFK
                     V"
     misc_feature    34980..35111
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            35127..35657
                     /gene="infC"
                     /locus_tag="VW361_000390"
     CDS             35127..35657
                     /gene="infC"
                     /locus_tag="VW361_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU9743515.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            35690..35890
                     /gene="rpmI"
                     /locus_tag="VW361_000391"
     CDS             35690..35890
                     /gene="rpmI"
                     /locus_tag="VW361_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU9743516.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            35942..36301
                     /gene="rplT"
                     /locus_tag="VW361_000392"
     CDS             35942..36301
                     /gene="rplT"
                     /locus_tag="VW361_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU9743517.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            36359..36739
                     /locus_tag="VW361_000393"
     CDS             36359..36739
                     /locus_tag="VW361_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9743518.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            36989..37789
                     /locus_tag="VW361_000394"
     CDS             36989..37789
                     /locus_tag="VW361_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU9743519.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            37800..38738
                     /locus_tag="VW361_000395"
     CDS             37800..38738
                     /locus_tag="VW361_000395"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU9743520.1"
                     /translation="MTTNRLQVSLPGLDLKNPIISASGCFGFGQEYAKYYDLDLLGSI
                     MIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAEKLPWLEREYPNLPIIA
                     NVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGLLIGQDPDLAYDVVKAA
                     VEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVGMRFDLKTRKPILANGT
                     GGMSGPAIFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEMYLAGASAIGVGTANFT
                     NPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            38780..40813
                     /locus_tag="VW361_000396"
     CDS             38780..40813
                     /locus_tag="VW361_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU9743521.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGVKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDYHSQAWYYFKSGGYMAKNETVDGYQLGSD
                     GKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAIT
                     ISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKY
                     YSADGLHFDDFKLENPFLFKDLTEATNYSAEELDKVFSLLNINNSLLENKGATFKEAE
                     EHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILG
                     ATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(40874..42529)
                     /gene="pavA"
                     /locus_tag="VW361_000397"
     CDS             complement(40874..42529)
                     /gene="pavA"
                     /locus_tag="VW361_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU9743522.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEM
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQAGEPFANLSDLLDTYYKNKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            42634..43131
                     /gene="ybeY"
                     /locus_tag="VW361_000398"
     CDS             42634..43131
                     /gene="ybeY"
                     /locus_tag="VW361_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU9743523.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            43112..43507
                     /locus_tag="VW361_000399"
     CDS             43112..43507
                     /locus_tag="VW361_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU9743524.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            43524..44423
                     /gene="era"
                     /locus_tag="VW361_000400"
     CDS             43524..44423
                     /gene="era"
                     /locus_tag="VW361_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU9743525.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADLGYNEREY"
     gene            44472..45296
                     /gene="mutM"
                     /locus_tag="VW361_000401"
     CDS             44472..45296
                     /gene="mutM"
                     /locus_tag="VW361_000401"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU9743526.1"
                     /translation="MPELPEVETVCRSLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            45296..45901
                     /locus_tag="VW361_000402"
     CDS             45296..45901
                     /locus_tag="VW361_000402"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU9743527.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            45888..47087
                     /locus_tag="VW361_000403"
     CDS             45888..47087
                     /locus_tag="VW361_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU9743528.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            47087..47236
                     /gene="rpmG"
                     /locus_tag="VW361_000404"
     CDS             47087..47236
                     /gene="rpmG"
                     /locus_tag="VW361_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9743529.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            47276..47509
                     /gene="secG"
                     /locus_tag="VW361_000405"
     CDS             47276..47509
                     /gene="secG"
                     /locus_tag="VW361_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU9743530.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            47611..49965
                     /gene="rnr"
                     /locus_tag="VW361_000406"
     CDS             47611..49965
                     /gene="rnr"
                     /locus_tag="VW361_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU9743531.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            49928..50395
                     /gene="smpB"
                     /locus_tag="VW361_000407"
     CDS             49928..50395
                     /gene="smpB"
                     /locus_tag="VW361_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU9743532.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            50411..51271
                     /gene="tehB"
                     /locus_tag="VW361_000408"
     CDS             50411..51271
                     /gene="tehB"
                     /locus_tag="VW361_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU9743533.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEVMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            51344..52297
                     /gene="coiA"
                     /locus_tag="VW361_000409"
     CDS             51344..52297
                     /gene="coiA"
                     /locus_tag="VW361_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU9743534.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            52316..54118
                     /gene="pepF"
                     /locus_tag="VW361_000410"
     CDS             52316..54118
                     /gene="pepF"
                     /locus_tag="VW361_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9743535.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            54120..54833
                     /locus_tag="VW361_000411"
     CDS             54120..54833
                     /locus_tag="VW361_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU9743536.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            54900..55841
                     /gene="prsA"
                     /locus_tag="VW361_000412"
     CDS             54900..55841
                     /gene="prsA"
                     /locus_tag="VW361_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU9743537.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(55960..56301)
                     /locus_tag="VW361_000413"
                     /pseudo
     CDS             complement(55960..56301)
                     /locus_tag="VW361_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            56714..56809
                     /locus_tag="VW361_000414"
                     /pseudo
     CDS             56714..56809
                     /locus_tag="VW361_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(57062..57682)
                     /locus_tag="VW361_000415"
     CDS             complement(57062..57682)
                     /locus_tag="VW361_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9743538.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(57682..58164)
                     /locus_tag="VW361_000416"
     CDS             complement(57682..58164)
                     /locus_tag="VW361_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU9743539.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMILQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(58164..59006)
                     /locus_tag="VW361_000417"
     CDS             complement(58164..59006)
                     /locus_tag="VW361_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU9743540.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(59101..59901)
                     /locus_tag="VW361_000418"
     CDS             complement(59101..59901)
                     /locus_tag="VW361_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU9743541.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            60045..61424
                     /gene="glmU"
                     /locus_tag="VW361_000419"
     CDS             60045..61424
                     /gene="glmU"
                     /locus_tag="VW361_000419"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU9743542.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGSCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            61434..61979
                     /locus_tag="VW361_000420"
     CDS             61434..61979
                     /locus_tag="VW361_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9743543.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            61991..62305
                     /locus_tag="VW361_000421"
     CDS             61991..62305
                     /locus_tag="VW361_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU9743544.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            62322..63014
                     /locus_tag="VW361_000422"
     CDS             62322..63014
                     /locus_tag="VW361_000422"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU9743545.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            63091..63582
                     /gene="rocS"
                     /locus_tag="VW361_000423"
     CDS             63091..63582
                     /gene="rocS"
                     /locus_tag="VW361_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU9743546.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            63680..64270
                     /locus_tag="VW361_000424"
     CDS             63680..64270
                     /locus_tag="VW361_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU9743547.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGGLDLSQLFD"
     gene            64279..66042
                     /locus_tag="VW361_000425"
     CDS             64279..66042
                     /locus_tag="VW361_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU9743548.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMDRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            66238..>66326
                     /locus_tag="VW361_000426"
     CDS             66238..>66326
                     /locus_tag="VW361_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU9743549.1"
                     /translation="MWYNLFMAYSIDFRKKVLSYCERTGSITEA"
BASE COUNT        19879 a        12148 c        14955 g        19344 t
ORIGIN      
        1 gcttgatttc ttgaccgagc gcttgcgatt gttttcataa gactgttgag catagtcggc
       61 agaataaacc tctttgaagc gcccttttcc aagacattgt cggactgtcc cacgcttgat
      121 ttcagtgtgg atagtttgag gaacttttcc aagcagagag gcaatttttc tatttgattt
      181 cccttctttt ttccatcttt cgattaagcg acggctatcg attgtcaaat gtttggcttt
      241 tgtagtataa ttgtcttgca tctctgtgcc tttcttgtgt ttgtggttga acaacaagta
      301 taacacagag gtgttttctt atgcctacaa gagctatcag ctagttgaac catctaattt
      361 ttaggagggc tgggtggcta acttcattat agaactttca tttacgaaca tatagtaaaa
      421 tgaaacaaga acagaacaaa tcgatcagga cagtaaaatc tatttctaat aatgttttag
      481 aagcagaagt gtactattct agtttcaatc tattatattt ttgtttttta tcaaaaaata
      541 ctttacaagt tcttaaaaac atgatatagt aataaagctt agaaaatgag atgatgtttt
      601 ctagcaaata taaacccgag taaaaaatgc ctacggacag gcagggttga atgccgaagc
      661 gtggttgaaa agccacatta ttgatagggt taaaagccta cttttataag ttgatgttag
      721 gacacttgtc ctaattcata aatttttagt gtggtgaaag cacacgtcat cttgtgaaac
      781 gatcaataaa gtacgtaata tttgctacta gagagttagg aaacatcggg aacagacata
      841 ctcaacagaa accaaaataa acacgtcaga agattgcaga gcaggtgaaa acctgctctt
      901 ttttcatgag tcaaccttta gttccttagt tttcataagg tcctaaaaat attgaaagga
      961 gtatgttttg aaagagttag atcaaaacca agccccaatt tatgaggcct tggtgaagtt
     1021 acgcaagaaa aggattgttc cctttgatgt tccaggtcac aagcgtggac ggggaaatcc
     1081 agaacttgtc gaactcttag gagaaaaatg tgtaggcatt gatgtcaatt cgatgaaacc
     1141 cttggataat ttaggccatc ctatttcgat tattcgtgat gcagaggagc tggctgcaga
     1201 tgcttttgga gctagccatg cctttctaat gattggtgga acaacttcat cggtgcagac
     1261 tatgattctg gcaacctgca aggcaggaga taagattatt ctgccacgaa atgtccataa
     1321 atctgctatc aatgcgttgg ttctatgtgg tgccattccc atctatatcg agatgagtgt
     1381 agatcctaag attggtatcg ctttaggtct tgaaaatgac cgagtagcac aggccataaa
     1441 ggaccatcca gatgctaagg ctatcctaat caacaatcct acttactacg gcatctgttc
     1501 agacctaaag gggttgacag aaatggctca tgaagctggc atgatggttt tagtagatga
     1561 agcccatgga gcgcatttgc atttcactgg taaacttcca atttctgcta tggatgcagg
     1621 agctgatatg gcagcagttt ccatgcataa gtctggtggg agtttgacac aaagttcgct
     1681 tcttttaatc ggggagcaga tgaatcccga atacgttcgt cagattataa acctgaccca
     1741 gtctacatct gcctcttact tattgatggc tagtttggat atttcacgtc gcaacttggc
     1801 ccttcgtggt aaagagtcgt ttgaggaagt cattgagcta tccgagtacg ctcgtcatga
     1861 aatcaatgcc attggcggtt actatgctta ctcaaaagag ttaatagatg gtgtgtcggt
     1921 ctgtgatttt gatgtaacca agttgtcagt ttacactcag ggaataggct taacaggtat
     1981 cgaggtttat gacctcttgc gagacgaata cgacattcag atcgagtttg gtgatatcgg
     2041 caatatcttg gcctatattt ccatcggcga ccgcatccaa gacatcgagc gcttggttgg
     2101 tgctctggct gatattaaga gactctattc acgagatggg aaggacttaa tagctggaga
     2161 atatattcag cccgagttgg tgctgtctcc acaagaagcc ttctattcag agagaaaaag
     2221 tttgacctta gatgagtctg ttggacaggt ctgtggagaa tttgtcatgt gctatcctcc
     2281 agggattcct atcttggctc ctggtgaacg cattacacga gaaattgtag actatatcca
     2341 attcgccaag gaacgtggtt gctccctcca agggacggaa gatccagagg tcaatcatat
     2401 caacgttatt aagagaaaga caaactataa gaaaagtcaa tagttttatc taaactattt
     2461 cttatttcaa tttgatgatt tggcgatgat tttagagcac ggcaaaaagc ccttgaatta
     2521 gaagcggtca atcgcttaat ttctatcagc ttatcaaatc ctgcctcaat ccttttctga
     2581 ggattagggt agcgtgtcaa gagttggtag gtatattctg aatgctttcc aacgatttta
     2641 tccaactcag gaaagatgat atcaagacaa cgagtgtatt gtactttcca atcagactgt
     2701 ttttcttgag acgatgaata tgtctagcca gtatttttag ttctacttgc cgattatcgt
     2761 gttgaaattg ttcacgattg gggtcagaaa gaagtttaag agcgatgcca tgagcgtctt
     2821 tcttatccgt tttagtcttg cgaagtgata atgatttggc aaattccttg atgagcaaag
     2881 gattgcaggt gtaaacttta tatccttgtt catgcaggaa gttcagtaga ttaaaggcat
     2941 aatgtccggt attttcaaga gcgatgagac agtcttggtt gagctgtcga agagacagat
     3001 ctaagagttc aaaaccagct ttattatttg aaaaagtgag tggtttaaga acagtttttc
     3061 ctggaacatt caaggctgta acatcgtgtt tatttttagc gacatcaatg cccacataaa
     3121 gcatgggagt acctccagat gtagtatttc aagtctactt ggttatccac gaattttttg
     3181 ccttgttacc ttagacgaga taaaacgtct atgcgttatc aaactcatta ccaattgaaa
     3241 caaaaaactg tggttagagc ctttcggaaa tcgtcaagcg attggaggga ataaactaat
     3301 ccacagtggc ttattccaag tataccactt gggctttggc agtagctaac tgcgctaaat
     3361 ataatataag gagaaataga tggatttatg gttttctgaa gttcatactc cagatgtcaa
     3421 attgtctctg agaacagcca agcaacttta cgctggaaaa agtgaatggc aggatatcga
     3481 agtcttggat acgccagctt ttgggaaaat actgatttta aatggccatg tcttgttctc
     3541 agatgcggat gatttcgtct acaatgaaat gaccgttcac gttcccatgg ctgtccaccc
     3601 aaatccaaag aaagtattgg ttattggggg tggtgacggc ggtgttgccc aagtattaac
     3661 actctatcct gaactggaac aaatcgatat cgtggaaccg gatgagatgt tggtcgaggt
     3721 ctgtcgtgag tatttcccag actttgctgc agggctagat gatcctcgtg ttaccattta
     3781 ctaccaaaat gggctacgct ttttgcgaaa ctgcgaagat gattacgata ttatcatcaa
     3841 cgatgcgaca gatccatttg gccatacgga aggactcttt accaaggaat tctacggcaa
     3901 tagttatcga gctctgaagg aagacggcat catgatttac cagcatggga gtcccttctt
     3961 tgacgaggat gagtcggcct gccgaagcat gcaccgcaag gtcaatcaat cctttccaat
     4021 cagtcgggtt tatcaggccc atattccaac tagcccagct ggctattggt tgtttggatt
     4081 tgcatcgaaa aaataccacc ctgtcaaaga ttttgacaag gaaggttgga aaaaacgcca
     4141 gcttttcaca gaatactaca ctgcaaactt acacgtggga tcctttatgt tgcccaagta
     4201 tgttgaggac attttagaag aagaggaagg aaaaaaatga gtcgtttact agttattggt
     4261 tgtgggggcg ttgcccaagt tgctatttca aagatttgtc aagatagcga aacatttaca
     4321 gagattatga ttgctagccg taccaagtca aaatgcgatg acttgaaagc gaagctagaa
     4381 ggcaaaacaa gtactaaaat tgaaactgca gcacttgatg ctgacaaggt tgaagaagtg
     4441 attgccctga ttgaaagcta caaaccagaa gctgttttga atgtagctct gccttatcaa
     4501 gatttaacca ttatggatgc ttgtttggca acaggtgttc actatatcga tacagccaac
     4561 tacgaagcag aagacacaga agaccctgag tggcgtgcta tctacgaaaa acgttgtaag
     4621 gaacttggtt ttacagccta ctttgactac tcatggcagt gggcttatca agagaaattc
     4681 aaagaagcag gcttgactgc tcttcttggt tctggctttg acccaggtgt aactagtgtc
     4741 ttttcagctt atgccctcaa acactatttt gatgaaatcc attatatcga cattttagac
     4801 tgtaatggcg gtgaccacgg ttatccattt gcaaccaact ttaatccaga aattaatctc
     4861 cgtgaggttt ctgcgccagg ttcttactgg gaagatggga aatgggtcga agtcgaagct
     4921 atgtctatca agcgtgagta tgatttccct caagttggac aaaaagatat gtatctcctt
     4981 caccatgaag aaatcgaatc attggccaag aacattccag gtgtcaaacg cattcgtttc
     5041 tttatgactt ttggtcaatc ttacttgacg cacatgaaat gtcttgaaaa tgttggactc
     5101 cttcgtacgg ataccattaa ctttaacggc caagaaattg ttccaattca atttttgaaa
     5161 gccttgcttc cagatcctgc tagccttggc ccacgtactg taggtaaaac caatattgga
     5221 tgtatcttta caggtgtcaa agatggcgtt gaaaagacta tctacatcta caatgtttgc
     5281 gaccatcaag agtgctatgc agaagtcggg tcacaagcaa tttcatacac gacaggcgtt
     5341 ccagccatga ttgggacaaa attagtcatg aacggaactt ggaaacaagc tggagtgtat
     5401 aaccttgagg agttagatcc agatccattc atggaagctt tgaatgagta tggtttgcca
     5461 tgggttgtgg ttgaaaatcc acaaatggtg gactaatgaa gttagaacaa gtaccaacac
     5521 cagcctatgt tattgacttg gccaagttag aagctaattg ccgcattcta caatatgtac
     5581 aagaagaggt cggttgcaag gtcttgcttg cccagaaggc atattccctc tacaaaactt
     5641 atcccttgat tagccagtat ctatcaggta cgacagctag tggactctat gaggccaaat
     5701 tggcaaggga agaatttcct ggtgaagtcc atgtatttgc gcctgctttc aaggatgcag
     5761 acttggagga attgcttggg ataacagacc atatcgtctt taactcagag agacagttgc
     5821 gtaagcatgg ggctcgttgt cgagaggctg gtgtcagtgt tggtttgcgc ctcaaccctc
     5881 agtgttcaac tcaaggagat cacgcgctct atgacccttg tgcaccaggt tctcgctttg
     5941 gagttactat agacaagatt ccgagtgatt tgctagattt ggttgacgga cttcattttc
     6001 ataccctttg cgagcaggga gcagatgatt tacaaacaac tttgaaagca gtagaagaac
     6061 agtttggtcc ctacttacat gaggtaaaat ggctcaatat gggtggtggt catcatatta
     6121 caagagaagg ttacgatgtg gatttgctga tttcagaaat caagcgtatc cgaaaaactt
     6181 acaatcttga aatctatatc gagcctggtg aagccattgc gcttaatgcg ggttatttag
     6241 caactgaggt attagatatt gtagaaaacg gtatggaaat cttggtttta gacgcctctg
     6301 cgacctgcca tatgcctgat gtacttgaga tgccctatcg tccacctttg agaaatggct
     6361 ttgaggcaca ggaaaaagcc catacctaca gactttcttc taatacctgt ctgacgggcg
     6421 atgtgattgg tgattatagt tttgaaaatc cagtccaaat cggagacaga ctttattttc
     6481 aagacatggc catttattct tttgtcaaaa ataatacctt taatggtatt ggattgccaa
     6541 gtctctatct catggacgaa cagggagact gtagcttact caaagctttt ggctatcaag
     6601 actttaaagg gagattatca tgatggacag tccaaaaaaa ttaggctatc acatgccagc
     6661 agagtacgaa ccccatcatg gtaccctcat gatatggccg actcgaccag gatcatggcc
     6721 ttttcaagga aaggatgcta aaagagcatt tactcagatc atcgagacta tagcagaagg
     6781 ggaaagagtc tatcttttgg tggagcaggc ctatctatct gaagcccaat cctatcttgg
     6841 ggacaaggtt gtttatttag acattcccac caatgatgcc tgggcgcgtg atactggccc
     6901 aaccattctc gtcaatgata aaggtaagaa attagccgtg gattgggcct tcaatgcttg
     6961 gggaggcacc tatgatggtc tttatcaaga ttatgaagag gatgaccaag tagccagtcg
     7021 ttttgctgag gccttggaaa ggcctgtcta tgatgctaaa ccttttgtac tggaaggagg
     7081 cgcaatccat agcgatggtc aaggaactat tctcgtaact gaaagttgct tgcttagtcc
     7141 tggtcgcaat cctaacttga ctaaagagga gattgaaaac acattattag aaagtcttgg
     7201 tgctgaaaaa gttatttggc ttccttatgg tatttatcag gatgaaacca atgaacacgt
     7261 cgataatgtt gctgcctttg ttggtcctgc tgaggttgtt ttggcttgga cagatgacga
     7321 aaatgatccc cagtatgcca tgtcaaaagc agatctcgaa ctcttagaac aggaaacaga
     7381 tgcaaaaggt tgtcacttca ccattcataa attgcctatc cctgcagttc gacaagttgt
     7441 gacagaagaa gatttgccag gctacatcta tgaagaagga gaagaagagc gatacgcagg
     7501 tgaacgacta gcagcttcct acgtaaactt ttatatcgcc aacaaggctg tcttggttcc
     7561 acagtttgag gatgtaaacg accaagtggc cttagatatc ctcagcaagt gtttcccaga
     7621 ccgtaaagtt gtcggaatac cagccagaga tattctctta ggtggtggca atatccactg
     7681 tatcacccaa caaattccag aataggagaa aaagatgaga aatgtaagag ttgcaaccat
     7741 tcagatgcaa tgcgctaagg atgtggcaac aaatatccaa accgcagagc gtttagtacg
     7801 tcaggctgct gagcaaggag cccaaattat tctcttgccc gagttgtttg aacatcccta
     7861 tttctgtcag gaacgtcagt atgactacta ccagtatgcc caatctgtag cggaaaatac
     7921 tgccattcag cattttaagg tgattgctaa ggaactacaa gttgttttac caatcagttt
     7981 ctatgaaaaa gatggtaatg tcttgtataa ctctattgcc gtcattgatg cagatgggga
     8041 agtgctgggc gtttatcgaa agacccacat accagatgac cattattatc aagaaaaatt
     8101 ctatttcacg cctggtaaca ctggtttcaa ggtctggaat actcgctatg ctaagattgg
     8161 tatcggtatc tgttgggatc aatggttccc tgaaacagcc cgctgtcttg cattgaatgg
     8221 tgctgaattg ctcttttatc ctacagctat cggttcagag ccaattttgg atacagatag
     8281 ttgtggtcac tggcaacgta ctatgcaagg gcacgcagca gcgaatattg ttccagtcat
     8341 cgcagccaat cgttatggtt tagaggaggt tactcctagt gaggaaaatg gcggacagag
     8401 ttccagtctt gacttctacg gttcctcctt tatgacggat gaaacaggag ctattctaga
     8461 acgagctgaa agacaagaag aagctgttct gttagctact tatgacctag acaagggagc
     8521 aagtgaacgt ctaaactggg gcttgtttcg agatagaaga ccagaaatgt atagacaaat
     8581 tacagattag tgtgggagaa atgagagatt cattctgcta gactaacttc ttattagcaa
     8641 ctataagata ctatggcatc tagtaaatcg atttttatga ttcgctattc ttgtctattg
     8701 attagtccgt attttaaata ttagcaaaaa agcaaatagc agtaacttct gtctatttgc
     8761 ttttcttttt ttatagaata tatttctcaa tagcacgcgc aacgccgtct tcttcgttgc
     8821 ttgaggtaac ggcatccgca agagatttga cataatcgct ggcatttccc attgcaatcc
     8881 caagccctgc aaactggagc atttcgatat cgttattagc atcgcccatg gccataatct
     8941 ctgaggaatc aatcttcaaa atctcagcaa gtcgtgaaag agcagtagcc tttgtcgttc
     9001 caagtggcat tgcttcataa atgacaggct gcgaacgaac tccactgaat cgttggcaaa
     9061 gctcttcagc aaaacgctgc tcaaaatcgt ctgtttgttc ttttgttcct aaaaacatac
     9121 cttggaacat ccggaacttt ccactagtcg cttcttcaag agaaatttca gtcaggtctg
     9181 aaaatactag tttagcatca ttttcaataa cttgattggg cttgccaccg agaacaaaat
     9241 aatgtgactc gtcaaaaagt gtcaactgaa catcactctt ttcagcaagg tcatagaggt
     9301 attcgatgtc agctggactc agttcttgcc agtcaaccaa gccccagtcg ctagtctggt
     9361 gagttgaaca accgttgtta acaatcacat attcgttctg gaggtcgagt cccagttttt
     9421 tgtagtaggg gaggacaccg aaaagggggc gacccgtaca gagaaccagt ttgacacctt
     9481 tttcaatggc ttggtgaata gcagcgatgt gagcctgtgg gatttccttg gcttcattga
     9541 ggagggttcc atccatatcc aaggctagta gtttaatcat aggtcttcct tctttatctt
     9601 ttgctattat tatagcatat tttggagaag aaattgatag aaagcttgag actaattgat
     9661 tttatagttt aagatgtttt gatgacaatt catgatttga agaggatatt tggcaaagat
     9721 atgctatact atgtttgtca atgttgcaac tagacaaatt aaaaaaccaa cttaatataa
     9781 tagttttttt tgtaagtagg tatgagtagc agattactca actaatctaa acaataacgg
     9841 aggaaatata tcatgatttt aatgacaaaa aatataaatc taacaaatga agaattagag
     9901 ctgatacaag gtggagcaga tccctatggt aaagaaccta atggttatta tccttggcaa
     9961 atggaaccag tattaactat gccggttcat ggattttgtc ccagaggaac cgatgattta
    10021 ggatatattg gaggaggtaa tcatctttgc aaaggaagtg ctgcgagatt ttaagtaaaa
    10081 tttattagga atatgaagaa acaaggggag aaaacagagg atttaatatg aaaaaacggg
    10141 ctattcaaat tttactagca ttgtccttaa ttttttacaa atcaacttgg ttttggagag
    10201 ttttcaatca cctcgcaaag ccctatctac cagcaagtcg tgaatttttt cagattctgc
    10261 ttttgatgga gagcggagtt cttttcttag cggtcatcta tctactggtt tttgcaggaa
    10321 agaaaatttt tcatttcaag tggcagctga ggtacttcat ctacctttta ctgggctaca
    10381 tcatttcata tatgtctgac ttcctctttt cgtatttcat atccccgcct tcaaatcaaa
    10441 tttctttgaa tgaaacggta gaaatgatgg ggagacagga gttcccttat ttcttgctca
    10501 tcgtttgctt catcgcccct attgctgagg aattgattta tcgaggtgtg cttatgacaa
    10561 cctttttcaa aaactcacct tggtacggag atgttttgct ttctgctatt attttcggtt
    10621 atattcatat caattttgct ttaactactc ttgctttttt catttatgct agtggaggtc
    10681 ttattttagc tctattgtat cgcatgacta aaaatctcta ctatccaata ctagttcata
    10741 ttctcattaa tatcactgcc ttctgggacg tgtggttgct cctattttca ggaagttagc
    10801 ttactaaaat aatgtcggaa ctttccagca ttttcttttt tcacaaatag tcaacgtttt
    10861 tctttccgat actgaagtgg tgtgtagcca cttatttttt tgaattgatt ttgaaaataa
    10921 ggttggcttg agaaaggcag atagtgaaga agaataggat gttctttttt cctttttgga
    10981 aaacttctaa aatatggtat aatgaaaaga taaagaagtt aggggtagaa gatgaacatt
    11041 caacaattac gctatgttgt ggccattgcc aatagtggta ctttccgtga agctgctgaa
    11101 aagatgtatg ttagtcagcc gagtctgtct atttctgttc gtgatttgga aaaagagttg
    11161 ggttttaaga ttttccgtcg gaccagctca gggactttct tgacccgtcg tgggatggaa
    11221 ttctatgaaa aatcgcaaga attggttaaa ggatttgata tttttcaaaa tcagtatgcc
    11281 aatcctgaag aagaaaaaga tgaattttct gttgctagcc agcactatga cttcttgcca
    11341 ccaactatta cggccttttc agagcgctat cctgactata agaacttccg tatttttgaa
    11401 tcaactactg ttcaaatatt agatgaagtg gcgcaagggc atagtgagat tgggattatc
    11461 tacctcaaca atcaaaataa aaaggggatt atgcaacggg ttgaaaaatt aggtctggag
    11521 gtcatcgaat tgattccttt ccatacccat atttatctcc gtgagggtca tcctttagcc
    11581 cagaaagagg aattagtcat ggaggattta gcggatttac caacggttcg tttcactcaa
    11641 gagaaagacg agtaccttta ttattcagag aactttgtcg ataccagcgc tagctcacag
    11701 atgtttaatg tgacagaccg tgccaccttg aatggtattt tggagcggac ggacgcctat
    11761 gcgacaggtt ctggattttt agatagtgac agtgttaatg gtattacagt tattcgtctc
    11821 aaggataacc tagataaccg catggtctat gttaaacgtg aagaagtgga gcttagtcaa
    11881 gctgggactc tcttcgtaga agtcatgcaa gaatattttg atcaaaagag gaaatcatga
    11941 aaaaaagagc aatagtggca gtcattgtac tgcttttaat tgggctggat cagttggtca
    12001 aatcctatat cgtccagcag attccactgg gtgaagtgcg ctcctggatt cccaatttcg
    12061 ttagcttgac ctacctgcaa aatcgaggtg cagccttttc tatcttacaa gatcagcagc
    12121 tgttattcgc tgtcattact ctggttgtcg tgataggtgc catttggtat ttacataaac
    12181 acatggagga ctcattctgg atggtcttgg gtttgactct aataatcgcg ggtggtcttg
    12241 gaaactttat tgacagggtc agtcagggct ttgttgtgga tatgttccac cttgacttta
    12301 tcaactttgc aattttcaat gtggcagata gctatctgac ggttggagtg attattttat
    12361 tgattgcaat gctaaaagag gaaataaatg gaaattaaaa ttgaaactgg tggtctgcgt
    12421 ttggataagg ctttgtcaga tttgtcagaa ttatcacgta gtcttgcgaa tgaacaaatt
    12481 aaatcaggcc aggtcttggt caatggtcaa gtcaagaaag ctaaatacac agtccaagag
    12541 ggtgatgtcg tcacttacca tgtgccagaa ccagaggtat tagagtatgt ggctgaggat
    12601 cttccgctag aaatagtcta ccaagatgag gatgtggctg tcgttaacaa acctcaggga
    12661 atggttgtgc acccgagtgc tggtcatacc agtggaaccc tagtaaatgc cctcatgtat
    12721 catattaagg acttgtcggg tatcaatggg gttctgcgtc cagggattgt tcaccgtatt
    12781 gataaggata cgtcaggtct tctcatgatt gctaaaaacg atgatgcgca tctagcactt
    12841 gcccaagaac tcaaggataa aaagtctctc cgcaaatatt gggcgattgt tcatggaaat
    12901 ctgcctaatg atcgtggtgt aattgaagcg ccgattggcc ggagtgaaaa agaccgtaag
    12961 aaacaggctg taactgctaa agggaagcct gcagtgacgc gttttcacgt cttggaacgc
    13021 tttggcgatt atagcttagt agagttgcaa ctggagacag ggcgcactca tcaaatccgt
    13081 gtccacatgg cttatatcgg ccattcagtc gctggtgatg aggtctatgg tcctcgcaag
    13141 actttgaaag gacatggaca atttcttcat gccaagactt taggttttac tcatccgaga
    13201 acaggtaaga ccttggaatt taaagcagat atcccagaga tttttaagga aaccttggag
    13261 agattgagaa agtaagaatg aaaaagaaat taactagttt agcacttgta ggcgcttttt
    13321 taggtttgtc atggtatggg aatgttcagg ctcaagaaag ttcaggaaat aaaatccact
    13381 ttatcaatgt tcaagaaggt ggcagtgatg cgattattct tgaaagcaat ggacattttg
    13441 ccatggtgga tacaggagaa gattatgatt tcccagatgg aagtgattct cgctatccat
    13501 ggagagaagg aattgaaacg tcttataagc atgttctaac agaccgtgtc tttcgtcgtt
    13561 tgaaggaatt gggtgtccaa aaacttgatt ttattttggt gacccatacc cacagtgatc
    13621 atattggaaa tgttgatgaa ttactgtcta cctatccagt tgaccgagtc tatcttaaaa
    13681 aatatagtga taatcgtatt actaattctg aacgtctatg ggataatctg tacggttatg
    13741 ataaggtttt acagactgct tcagaaaaag gtgtttcagt tattcaaaat atcacacaag
    13801 gggatgctca ttttcagttt ggggacatgg atattgagct ctataactat gaaaatgaaa
    13861 ccgattcatc gggtgaatta aagaaaattt gggatgataa ttccaattcc ttgattagtg
    13921 tggtaaaagt caatggcaag aaaatttacc ttgggggcga cttagataat gttcatggag
    13981 cagaagacaa gtatggtcct ctcattggaa aagttgattt gatgaagttt aatcatcacc
    14041 atgataccaa caaatcaaat accaaggatt tcattaaaaa tttgagtccg agtttgattg
    14101 ttcaaacttc ggatagtcta ccttggaaaa atggtgttga tagtgagtat gttaattggc
    14161 tcaaagaacg aggaattgag agaatcaacg cagccagcaa agactatgat gcgacagttt
    14221 ttgatattcg acaagacggt ttagtaaaca tttcaacttc ctacaagccg attccaagtt
    14281 ttcaagctgg ttggcataag agttcatatg gaaactggtg gtatcaagcg cctgattcta
    14341 caggagaata tgctgtcggt tggaatgaaa ttaagggtga atggtattac tttaaccaaa
    14401 cgggtatctt attacagaat caatggaaaa aatggaacaa tcgttggttc tatttgacag
    14461 actctggtgt tgctgctaaa aattggaaga aaatcgctgg aatctggtat tattttaaca
    14521 aagaaaatca gatggaaatt ggttgggttc aagataaaga gcagtggtat tatttggatg
    14581 ttgatggttc tatgaagaca ggatggcttc aatatatggg gcaatggtat tactttgctc
    14641 catcagggga aatgaaaatg ggctgggtaa aagataaaga aacctggtac tatatggatt
    14701 ctactggtgt catgaagaca ggtgagatag aagttgctgg tcaacattat tatctggaag
    14761 attcaggagc tatgaagcaa ggctggcata aaaaggcaaa tgattggtat ttctacaaga
    14821 cagacggttc acgagctgtg ggttggatca aggacaagga taaatggtac ttcttgaaag
    14881 aaaatggtca attacttgtg aacggtaaga caccagaagg ttatactgtg gattcaagtg
    14941 gtgcctggtt agtggatgtt tcgatcgaga aatctgctac aattaaaact acaagtcatt
    15001 cagaaataaa agaatccaaa gaagtagtga aaaaggatct tgaaaataaa gaaacgagtc
    15061 aacatgaaag tgttacaaat ttttcaacta gtcaagattt gacatcctca acttcacaaa
    15121 gctctgaaac gagtgtaaac aaatcggaat cagaacagta gtagaaaaga aggttttagg
    15181 gccttctttt tcctatcaac tcttttctat ttcctgttat tcatgttata atggataaat
    15241 atgaataatc ggagtgagac tatgaaatac aaacggattg tctttaaggt gggtacttct
    15301 tctctgacaa atgaggatgg aagtttatca cgtagtaagg taaaggatat tacccagcag
    15361 ttggctatgc tgcacgaggc tggtcatgag ttgattttgg tgtcttcagg tgccattgcg
    15421 gctggttttg gagccttagg atttaaaaag cgtccgacta aaattgctga taaacaggct
    15481 tcagcagcgg tagggcaggg acttttgttg gaagaatata cgaccaatct tctcttgcgt
    15541 caaatcgttt ctgcacaaat cttgctgacc caagatgact ttgtggataa gcgtcgttat
    15601 aaaaatgccc atcaggcttt gtcggttttg ctcaaccgtg gggcaattcc tatcatcaat
    15661 gagaatgata gtgtcgttat tgatgagctc aaggttgggg acaatgacac tctaagtgct
    15721 caagtagcgg cgatggtcca agcagacctt ttagttttct tgacagatgt ggacggtctc
    15781 tatactggaa atcctaattc agatccaaga gccaaacgct tggagagaat cgagaccatc
    15841 aatcgtgaga ttattgatat ggctggtgga gctggttcgt caaacggaac tgggggtatg
    15901 ttaaccaaaa tcaaggctgc aactatcgcg acggaatcag gagttcctgt ttatatctgc
    15961 tcatccttga aatcagattc catgattgag gcggcagagg agaccgagga tggttcttac
    16021 tttgttgctc aagagaaggg gcttcgtacc cagaaacaat ggcttgcctt ctatgctcag
    16081 agtcaaggtt ctatttgggt tgataaaggg gctgcggaag ctctctctca acatggaaag
    16141 agtcttctct tatctggtat cgttgaagca gaaggagcct tttcttacgg tgatatcgtg
    16201 acagtatttg acaaggaaag tggaaaatca cttggaaaag gacgcgtgca atttggagca
    16261 tctgctttgg aggatatatt gcgttctcaa aaagccaagg gtgtcttgat ttaccgtgac
    16321 gactggattt ccattactcc tgaaatccaa ctacttttta cagaatttta gaggtaaact
    16381 atggtgagta gacaagaaca atttgaacag gtacaggctg ttaaaaaatc gattaacaca
    16441 gctagtgaag aagtgaaaaa tcaagccttg ctagccatgg ctgatcactt agtggctgct
    16501 actgaggaaa ttttagcggc taatgccctc gatatggcag cggctaaggg gaaaatctca
    16561 gatgtgatgt tggatcgtct ttatttggat gcagatcgta tagaagcgat ggcaagagga
    16621 attcgtgaag tggttgcctt cccagatcca atcggtgaag ttttagaaac aagtcagctt
    16681 gaaaatggtt tggttatcac aaaaaaacgt gtagctatgg gtgtcatcgg tattatctat
    16741 gaaagccgtc caaatgtgac gtctgatgcg gctgctttga ctcttaagag tggaaatgcg
    16801 gttgttcttc gtagtggtaa ggatgcctat caaacaaccc atgccattgt cacagccttg
    16861 aagaagggct tggagacgac tactattcac ccaaatgtga ttcaactggt ggaagatact
    16921 agccatgaaa gtagttatgc tatgatgaag gccaagggct atctagacct cctcattcct
    16981 cgtggaggag ctggcttgat caatgcagtg gttgagaatg cgattgtacc tgttatcgag
    17041 acagggactg ggattgtcca tgtctatgtg gataaggatg cagacgaaga caaggcgctg
    17101 tctatcatca acaatgctaa aaccagtcgt ccttctgttt gtaatgccat ggaggttctg
    17161 ctggttcatg aagacaaggc agcaagcatc cttcctcgct tggatcaaat gctggttgca
    17221 gagcgtaagg aagctggact ggaaccaatt caattccgct tggatagcaa agcaagccag
    17281 tttgtttcag gtcaagcagc tgagacccaa gactttgaca ccgagttttt agactatgtc
    17341 cttgctgtta aggttgtgag cagtttagaa gaagcggttg cgcacattga atcccacagc
    17401 acccatcatt cggatgctat tgtgacggaa aatgctgaag ctgcagcata ctttacagat
    17461 caagtggact ctgcagcggt gtatgttaat gcctcaactc gtttcacaga tggaggacaa
    17521 tttggtcttg gttgtgaaat ggggatttct actcagaaat tgcacgcgcg tggtccaatg
    17581 ggcttgaaag agttgaccag ctacaagtat gtggttgctg gtgatgggca gataagggag
    17641 taagagatga agattggatt tatcggtttg gggaatatgg gtgctagctt ggcaaaatct
    17701 gtcttgcaga ctaggacgtc agatgagatt ctccttgcca atcgtagtca agctaaggta
    17761 gatgctttca ttgcagactt tggtggtcag gcttccagca atgaagaaat gtttgcagaa
    17821 gcagatgtga tttttctagg agttaagcct gctcagtttt ctgaactgct ttctcaatac
    17881 cagaccatcc ttgaaaaaag agaaagtctt cttttgattt cgatggcagc tggattgacc
    17941 ttagaaaaac tagcaagtct tatcccaagc caacaccgaa ttattcgtat gatgcctaat
    18001 acccctgctt ctatcgggca aggagtgatt agttatgcct tgtctcctaa ttgcagggct
    18061 gaggacagtg agatcttttg tcagctttta gccaaggctg gtctcttggt tgaattagga
    18121 gaaagcttaa tcaatgcagc gacaggtctt gcaggttgtg gaccagcctt tgtctatctc
    18181 tttattgagg ccttggcaga tgcaggtgtt cagacgggat taccacgaga aacagccttg
    18241 aaaatggcag cccaaactgt ggtaggagct gggcaattgg tcctagaaag ccagcaacat
    18301 cctggagttt tgaaagatca agtttgtagt ccaggcggtt cgactattgc tggcgtagca
    18361 agcctagaag cgcatgcttt tcgaggcaca gtcatggagg cagttcatca agcctataaa
    18421 cgaacacaag aactaggtaa ataagaggta gctttgactg cctcttttat ggtggttgat
    18481 actcttcgaa aatcaaattc aaactgcgtc agcttcacct tgccgtactc aagtacagcc
    18541 tgcggctagc ttcctagttt gctctttgat tttcattgag tatgaaatga gaagacaaaa
    18601 agattgtcac aaacccctat ttttttgata gaatagaagt agtaaaaaag aaatgagtta
    18661 gacatgtcaa aaggattttt agtctctctt gagggaccag agggagcagg caagaccagt
    18721 gttttagagg ctctgctacc aattttagag gaaaaaggag tagaggtgtt gacgacccgt
    18781 gaacctggcg gagtcttgat tggggagaag attcgggaag tgattttgga tccaagtcat
    18841 actcagatgg atgctaaaac agagctactt ctctatattg ccagtcgcag acagcatttg
    18901 gtggaaaaag ttcttccagc ccttgaagct ggcaagttgg tcatcatgga tcgttttatc
    18961 gatagttctg ttgcctatca gggatttggt cgtggcttag atattgaagc cattgactgg
    19021 ctcaatcagt ttgcgacaga tggcctcaaa cccgatttga cactctattt tgacatcgag
    19081 gtggaagaag gactggctcg tattgctgct aatagtgacc gcgaggttaa tcgtttggat
    19141 ttggaagggt tggacttgca taaaaaagtt cgtcaaggct acctttctct tctggataaa
    19201 gagggaaatc gcattgtcaa gattgatgct agtctccctt tggagcaagt tgtggaaact
    19261 accaaggctg tcttgtttga cggaatgggc ttggccaaat gaaacaagat caactaaagg
    19321 cttggcaacc agctcagttt gaccgttttg tccgtatctt agaacaagac cagctcaatc
    19381 acgcctatct cttttcaggt ttctttggaa gcttggaaat agcgcaattt ttagctaaga
    19441 gcctcttttg tacggataaa gttggcgtct taccatgtga gaaatgccga agttgcaagc
    19501 tgattgaaca ggaagagttt ccagatgtca ccttgattaa gccagtcaat caggtcatca
    19561 agacagaacg cattcgggaa ttggtgggac agttttctca agcagggatt gaaagccagc
    19621 aacaggtctt tatcatcgag caagcggata aaatgcatcc caacgcagcc aattctctgc
    19681 tcaaggtcat cgaagaaccc cagagtgaag tttatatttt cttcttgact agcgatgagg
    19741 aaaagatgtt accgacaatc cgaagtcgga cccagatctt ccactttaaa aagcaagaag
    19801 aaaaacttat cttactctta gaacaaatgg gacttgttaa gaaaaaagcg actcttttag
    19861 ctaagtttag tcaatcgcga gctgaagcag aaaagttggc taatcaggca agtttttgga
    19921 ccttggtcga tgaaagtgaa cgcctgctga cttggttagt agctaagaaa aaagaaagtt
    19981 atctacaggt tgccaaatta gccaacttgg cagatgataa ggaaaaacag gatcaggttt
    20041 tacggattct tgaagttctc tgtgggcagg acctcttgca ggtaagagta agagtgattc
    20101 tacaagattt actagaagct agaaaaatgt ggcaagttaa tgtcagcttt caaaatgcca
    20161 tggaatatct ggtcttgaaa gaaatataaa ctcaaaaatg aatgataaag aaaggaaagg
    20221 gctgttttat ggacaaaaaa gaattatttg acgcgctgga tgatttttcc caacaattat
    20281 tggtaacctt agccgatgtg gaagccatca agaaaaatct caagagcttg gtagaagaaa
    20341 atacagctct tcgcttggaa aatagtaagt tgcgagaacg cttgggtgag gtggaagcag
    20401 acgctcccgt caaggccaag catgttcgcg aaagtgtccg tcgtatttac cgtgatggat
    20461 ttcacgtatg taatgatttt tatggacaac gtcgagagca ggacgaagaa tgtatgttct
    20521 gtgatgagtt gttatacagg gagtaagcat gcaaattcaa aaaagtttta aggggcagtc
    20581 tccctatggc aagctgtatc tagtggcaac gccgattggc aatctagatg atatgacttt
    20641 tcgtgctatc cagaccttga aagaagtgga ctggattgct gctgaggata cgcgcaatac
    20701 agggcttttg ctcaagcatt ttgacatttc caccaagcag atcagttttc atgagcacaa
    20761 tgccaaggaa aaaattcctg atttgattgg tttcttgaaa gcagggcaaa gtattgctca
    20821 ggtctctgat gccggtttgc ctagcatttc agaccctggt catgatttag ttaaggcagc
    20881 tattgaggaa gaaattgcag ttgtgactgt tccaggtacc tctgcaggaa tttctgcctt
    20941 gattgccagt ggtttagcgc cacagccaca tatcttttac ggttttttac cgagaaaatc
    21001 aggtcaacag aagcaatttt ttggctctaa aaaagattat cctgaaacac agatttttta
    21061 tgaatcgccc catcgtgtgg cagatacatt ggaaaatatg ctagaagtct acggtgaccg
    21121 ctcggtagtc ttggttagag aattgaccaa aatctatgaa gaataccaaa gaggtacaat
    21181 ttctgaattg ctggaaagca tctctgaaac gtctctcaag ggtgaatgtc ttctgattgt
    21241 tgaaggtgcc agcaaaggtg tggaggaaaa ggatgaggaa gacttgttct tagaaatcca
    21301 agcccgtatc cagcaaggca tgaagaaaaa tcaagctatt aaggaagtcg ctaagattta
    21361 ccagtggaat aaaagtcagc tctacgctgc ctaccacgac tgggaagaaa atcaagaaaa
    21421 tgactaaaca gggaagtttg ccttcttccc tttttttgtt atactagtag aagaaaaaat
    21481 tagaaagatt tgtgggagtg aaaaagtcct gtggactttt tcagcctgag ccaagaaact
    21541 cgaaagctcg taagtctgat tggctttttc aatgtgaatc ttaacttcac actcccaaag
    21601 aggtattagt gtcgtgtctc aatcttatat caatgttatc ggtgctggtt tggcaggttc
    21661 tgaagcagct taccaaatcg cagagcgtgg tattccagtt aaactatatg aaatgcgtgg
    21721 tgtcaagtct acaccccagc ataaaacaga caattttgct gagttggttt gttccaattc
    21781 tttgcgtggg gatgctttga caaatgcagt tggtcttctc aaggaagaaa tgcgtcgctt
    21841 gggttctgtt atcttggaat ctgctgaggc tacacgtgtt cctgccggtg gagcccttgc
    21901 ggtggatcgt gatggtttct ctcaaatggt gaccgaaaaa gtggtcaacc accccttgat
    21961 tgaagtggtg cgtgatgaaa ttacagaatt gccaacagat gttattacag ttgtggcgac
    22021 tggtcccttg actagcgatg ccctggctga aaagattcat gcccttaata atggcgatgg
    22081 cttctatttc tacgatgcag cagcgcctat tatcgatgtc aacactatcg atatgagtaa
    22141 ggtctatctc aaatctcgtt atgataaggg agaagcagcc tatctcaatg ctccaatgac
    22201 caagcaagag tttatggatt tccatgaagc cttggtcaat gcggaagaag caccgctcaa
    22261 ttcttttgaa aaagaaaagt actttgaagg atgtatgcca atcgaagtta tggccaaacg
    22321 tggcattaaa actatgcttt atggccctat gaagccagtc ggtcttgagt atccggacga
    22381 ctacacagga cctcgtgatg gagaatttaa aacaccttat gcggttgtgc aacttcgtca
    22441 ggataatgca gctggtagcc tctacaatat cgttggtttc cagacccacc tcaaatgggg
    22501 agaacaaaag cgtgtcttcc aaatgattcc gggtcttgaa aatgcggagt ttgtccgtta
    22561 tggtgtcatg catcgcaatt cttacatgga ttcaccaaat cttcttgagc agacttaccg
    22621 ttccaagaaa caaccaaatc tcttctttgc tggtcagatg acgggggtgg aaggctatgt
    22681 tgagtcggcg gcttcgggct tagttgcggg aattaacgca gctcgtctct tcaaggaaga
    22741 aagcgaggtt attttccccg agacgacagc gattggaagc ttagctcatt acattaccca
    22801 tgccgacagc aaacatttcc aaccaatgaa tgtcaatttt gggatcatca aggagttgga
    22861 aggcgagcgt atccgtgata agaaggctcg ttatgaaaaa attgcagagc gtgcccttgc
    22921 cgacttagaa gaatttttga ctgtctaatt tttttgaaag aattgctcat gatactataa
    22981 aaatcttaga aattgtgata aaataggtag gatgaaagaa ggagagtgaa aatggcgaat
    23041 cccaagtata aacgtatttt aatcaagtta tcaggtgaag cccttgccgg tgaacgtggc
    23101 gtagggattg atatccaaac agttcaaaca atcgcaaaag agattcaaga agttcatagc
    23161 ttaggtatcg aaattgccct tgttattggt ggaggaaatc tctggcgtgg agaacctgca
    23221 gcagaagcag gtatggaccg tgttcaggca gattacactg gaatgcttgg gactgttatg
    23281 aatgctcttg tgatggcaga ttcattgcaa caagttgggg ttgatacgcg tgtacaaaca
    23341 gctattgcta tgcaacaagt ggcagagcct tatgtccgtg gacgtgccct tcgtcacctt
    23401 gaaaaaggcc gtatcgttat ctttggtgct ggaattggtt caccatactt ctcgacagat
    23461 acaacagcgg cccttcgcgc agctgaaatc gaagcagatg ccatcctcat ggctaaaaat
    23521 ggcgtcgatg gtgtgtacaa tgccgatcct aagaaggaca agacagccgt taagtttgaa
    23581 gaattgaccc accgtgatgt tatcaacaaa ggtcttcgta tcatggactc aacagcctca
    23641 accctctcaa tggacaacga cattgacttg gttgtcttca acatgaacca atcaggcaac
    23701 atcaaacgtg tcgtatttgg tgaaaatatc ggaacaacag tttcaaataa tatcgaagaa
    23761 aaggaataag aaagaatatg gctaacataa ttattgaaaa agctaaagag agaatgaccc
    23821 agtctcacca atcacttgct cgtgaatttg gtggtatccg tgctggtcgt gccaatgcaa
    23881 gcttgcttga ccgtgtacat gtagaatact atggagtcga aactcctctt aaccaaatcg
    23941 cttcaattac gattccagaa gcgcgtgttt tgttggtaac accatttgac aagtcttcat
    24001 tgaaagacat cgaacgtgcc ttgaacgctt ctgatcttgg tatcacaccg gctaatgacg
    24061 gttctgtgat tcgcttggtt atcccagctc ttacagaaga aactcgtcgt gaccttgcta
    24121 aagaagtgaa gaaggtcggc gaaaatgcta aagtggctgt ccgcaatatc cgtcgcgatg
    24181 ctatggacga agctaagaaa caagaaaaag caaaagaaat cactgaagac gaattgaaga
    24241 ctcttgaaaa agatattcaa aaagtaacag acgatgctgt taaacacatc gacgacatga
    24301 ctgctaacaa agagaaagaa cttttggaag tctaaaaata aacagaaaaa ctcagttggc
    24361 attgctggct gagttttatt cgaaagaagg aaatatgaat acaaatcttg caagttttat
    24421 cgttggactg atcatcgatg aaaatgaccg tttttacttt gtgcaaaagg atggtcaaac
    24481 ctatgctctt gctaaggaag agggccaaca tacagtaggg gatacggtca aaggttttgc
    24541 atacacggat atgaagcaaa aactccgcct gacaacctta gaagtgactg ccactcagga
    24601 ccaatttggt tggggatgtg tcacagaggt tcgtaaggac ttgggtgtct ttgtagatac
    24661 aggccttcct gacaaggaaa tcgttgtgtc actcgatatt ctccctgagc tcaaggaact
    24721 ctggcctaag aagggcgacc aactctacat ccgtcttgaa gtggataaga aagaccgtat
    24781 ctggggcctc ttggcttatc aagaagactt ccaacgtctt gctcgtcctg cctacaacaa
    24841 catgcagaac caaaactggc cagccattgt ttaccgtctc aagctgtcag gaacttttgt
    24901 ttacctacca gaaaataata tgcttggttt tattcatcct agcgagcgtt acgcagagcc
    24961 acgtttgggg caagtattag atgcgcgcgt tattggtttc cgtgaagtgg accgcactct
    25021 gaacctctcc ctcaaaccac gctcctttga aatgttggaa aacgatgctc agatgatttt
    25081 gacttatttg gaaagtaatg gcggtttcat gaccttaaat gataagtcat ctccagacga
    25141 catcaaggca acctttggca tttctaaagg tcagttcaag aaagctttag gtggtcttat
    25201 gaaggctggt aaaatcaagc aggaccagtt tgggacagag ttgatttagg gaggcttatg
    25261 agaaaatcat tttacacttg gctcatgacc gagcgcaatc ctaaaagtaa cagtcccaaa
    25321 gcaattttgg cagacctcgc ttttgaagag gcagcttttc caaaacatac agatgatttt
    25381 gatgaggtca gtcgcttttt ggaggagcat gccagtttct cttttaacct aggagatttt
    25441 gacagcattt ggcaggaata tctagaacac tagcatttat tcattgggtt tgggctagta
    25501 atttctccat ccctctgcta taataaaaag aaataaaagg attagagagg ttctttattt
    25561 gaaggaacat tcaatagaca ttcaactgag tcatccagat gacctgtttc atctttttgg
    25621 ttccaatgaa cgccatcttc gtttgatgga agaagagctt gatgttgtga ttcatgctcg
    25681 tacggagatt gtccaggttt tgggagaaga gtctgcctgt gaggaagccc gtcaagttat
    25741 tcaggctttg atggtcttgg taaatcgtgg gatgaccgtt ggtacgccag atgtagtcac
    25801 tgcgattagc atggtcaaaa atgatgaaat tgacaagttt gtcgcccttt acgaagaaga
    25861 aattatcaaa gataatactg ggaaacctat ccgtgtcaaa accctagggc aaaagcttta
    25921 tgtggacagt gtcaaacagc atgatgtgac ctttggaatt gggccagcag gtacagggaa
    25981 gaccttcctt gcagtgacct tggcagtgac tgcccttaaa cgtgggcaag tcaagcgaat
    26041 tatcctaact cgtccagcgg tggaagcggg agagagtctt ggatttcttc cgggtgatct
    26101 taaggagaag gtggatcctt accttcgtcc tgtttacgat gccttgtatc aaattcttgg
    26161 gaaagaccaa acgactcgtc tcatggagcg tgaaattatc gaaattgcgc cccttgccta
    26221 tatgcgtggc cggaccttgg atgatgcctt tgtcattctc gatgaggcgc aaaacacgac
    26281 catcatgcag atgaagatgt tcttgacgcg tttaggcttt cattctaaga tgattgtcaa
    26341 tggagatatc agtcagattg acctgccacg taatgtcaag tccggtttga ttgatgctca
    26401 agagaaactc aagaacatcc atcagattga ctttgttcat ttttcagcca aggatgtggt
    26461 tcgccatcca gttgtcgctc agattatccg agcctatgaa tattctactg aagttgcaca
    26521 cgactgattt tgaggaagtt cgcctgcaaa agaatatact tttgagagag gaaaatccag
    26581 ttgtataggc taaaggtttt atccaaaggt ttgagacaac gattaggcac gatggaaaga
    26641 acttttatgt ggctgatgac gatcagtgca tcttcctgtg tcataatcac agggcacaag
    26701 aaagtaggaa tttgaaaaga tgattgacca actatctaag tattacagtt gtaggatact
    26761 aactgaaaag gatattccaa gtattttatc tttatatgaa agtaatcctc tgtattttca
    26821 gcattgtcca ccagagccaa attttgcaac tgtaaaagag gacatgcttt gtctacctga
    26881 aggtaaagct aaggctgata agttttttgt tggattttgg aatggatctg accttgtggc
    26941 tgttatggat tttgtctatg catatcctga tgaggagact gtttttattg gtttgtttat
    27001 ggttgatcaa gcctatcaga ggaaagggat tggtagtcat attgtgacag aagcactagc
    27061 ttattttgct aagaactttc gaaaggcacg tttggcttat gttaagggaa atccgcaatc
    27121 tcagcatttt tgggaaaagc agggctttaa atcaattgga tgcgaggtta agcaagaact
    27181 ctatacggtt gttatcgctg aacagagcct agaagattag aaatggcatc aagtaagaac
    27241 tatttggaat ttgttttgga acaattatca ggattagatg atgtgactta ccgttccatg
    27301 atgggggagt atattcttta cttccgcggc aagattattg gcggcattta tgacgatcgc
    27361 tttttagtta aacccgtgca agcagtctta gataagattg accaatcttc ttttgagttt
    27421 ccatacaaag gtgccaaaga aatgatttga gtggaagaac ttgataataa gatgtttcta
    27481 taagacctga ttttagctat gtataaccaa ctgccaacgc ccaaacctaa aaagaaaaag
    27541 caagggtgaa cgaagtaaaa aagaagtctg ctaaggccct gtctttgcac gggtaaaatt
    27601 ttatatataa aaagaagctg ggactaaaga gctcagcttc ctttggttta tataattgtc
    27661 attacaagac gaagtggttg ggcgaaactc tgttgacttt attcaattta gagtttctta
    27721 tgcacaattg agtctggaac gaaagtctcc agttgcaaag tatacagtat aataaaccaa
    27781 cgatgtaata gctgatgaca caaagcacag tgggtaggac ttgcgaagtc acccttttct
    27841 tttcaaaatt tatactaaat cattgatatc agtgtagtca cgattaagtc cttgagcaac
    27901 tggtaggcta gtcaagtaac cttgataagt ggtcacacct tgacgcaagc cttcatcttc
    27961 agagattgct tgtgcgaatc ctttgccagc caaagcttcg atataaggaa gagtgacatt
    28021 ggttagggcg atggttgaag tgcgggtaac cgcaccaggg atattggcaa cggcatagtg
    28081 gagaacaccg tgtttttcat agacgggttc atcgtgcgtt gtcacacggt cagctgtttc
    28141 gataaggcca ccttggtcaa cagcaacgtc aacgatacag agcctggacg catttgtttg
    28201 accatctcat ctgtcaccaa ttccggtgct tttgcaccag ggatgagaat ggctccaatc
    28261 accacatcag catctctcac acttgcttca atgttgaatg aattagatat aagagtttga
    28321 atttgacttc caaagacttc ttctagaact gagagacgct tggcactaat atctaaaata
    28381 gtcacttgag caccaagacc aagggcgatg cgggcagcat gtgtaccgac gacaccatca
    28441 ccgatgatag ttacttttcc ttttggaaca cctggtacac caccaggtag aacaccagag
    28501 ccaccagctt gcttagtaag gaagtgagct ccgatttaaa cagccatacg acctgcaacc
    28561 tcactcatag gaacgaggag cggtagttgt ccttgattgt cacgaacagt ttcataggca
    28621 attcctgttg tttttgctgc taacatagca tctgctaatt ctggagcagc ggccatgtgc
    28681 aagtaggtga agagaagaag atcgtcgcgc aagtaaccgt attcagaact taaaggttct
    28741 tttactttca caaccaactc tgctgcccaa gcttcaccag cagtagcgac aatctcagct
    28801 ccttgctttt gatagtcagc atcagtaaag ccagaaccga gaccagcatt tgtttcgata
    28861 aggacacgat gaccacgact aactaagcta tgaacacctg caggtgtgag ggcgacacgg
    28921 ttttcgttat ttttaatttc ttttgggatt ccgattaaca ttgagataac ctacctttca
    28981 attgacggtc ttgttttggt tgtcacattc cagttcataa atcaaaaatg tgacggtttc
    29041 attgtatatg aaaccgcttc aaaaatcaag aaaaacttgt catccaaatt tttttatgct
    29101 agactagtga aaatcaagct ctaatggagg gaaaagtatg gaatcaatat ttgtgaaatt
    29161 tgcccagtat ccgtctatag aaacggagcg tttattgctt agacctgtaa ctttggatga
    29221 tgcggaagca atgtttgact atgcctcgga caagggtaat acacgttaca cttttccaac
    29281 caatcaaagc ttggaagaaa ccaagaataa cattgctcag ttctacttgg ctaatccctt
    29341 gggacgttgg ggaatagaac taaaaagcaa tggcaaattt atcggaacaa ttgatttgca
    29401 caagattgat cctgttctta agaaggtagc tattggttat attatcaacc aaacgtattg
    29461 gaatcaagga ttaacgacag aaaccaatcg tgctgtgatt gagctagctt ttgagaagat
    29521 aggaatgaat aagttagttg ctttatacga taaggctaat cccgcatcag gaaaggtcat
    29581 ggagaaatca ggaatgcgtt tttcccatgc agaaccatat gcttgtatgg accagcatga
    29641 aaaaggccga atcgtgacaa gagttcatta tgtcttgacc aaggaagact attttgcaaa
    29701 taaataagca gttgaaaaga aatttttcga ctgttttttc ttcctcttac gaataatcta
    29761 agagaggaga aaatatggaa gcaattatcg agaaaatcaa agagtataaa atcatcgtca
    29821 tctgtactgg tctgggcttg cttgtaggag gatttttcct gctaaaacca gctccacaaa
    29881 cacctgtcaa agagacgaat ttgcaggctg aagtcgcagc tgtttccaag gatttggtat
    29941 ccgaaaagga agtgaacaag gaagaaaagg aagaacccct tgaacaagat ctaatcacag
    30001 tagatgtcaa aggtgctgtc aaatcgccag ggatttatga cttgcctgta ggtagtcgag
    30061 tcaatgatgc tgttcagaag gctggtggct tgacagagca agcagacagc aagtcgctca
    30121 atctagctca gaaagttagt gatgaggctc tggtttacgt tcctactaag ggagaagaag
    30181 cagttagcca acagactggt ttggggacag cttcttcaat aagcaaggaa aagaaggtca
    30241 atctcaacaa ggccagtctg gaagaactca agcaggtcaa gggactggga ggaaaacgag
    30301 ctcaggacat tatcgaccat cgtgaggcaa atggcaagtt caagtcagta gacgagctca
    30361 agaaggtctc tggcattggt ggcaaaacaa tagaaaagct taaagactat gttacagtgg
    30421 attaagaatt tctctattcc cctaatttac ctgagttttc tattactttg gctttattac
    30481 gctattttct cagcatctta tcttgctttg ttgggctttg tttttctgct agtctgtctc
    30541 tttatccaat ttccgtggaa atctgctggt aaagttctaa taatttgcgg aatctttgga
    30601 ttttggtttg tttttcaaaa ttggcaacag agtcaagcga gtcaaaatct ggcggattct
    30661 gttgaaaggg tacggatttt gcctgatact attaaggtta atggtgatag tctatccttt
    30721 cgtggcaagt ctaacggtcg tgctttccaa gtctattata aactccagtc cgaggaggag
    30781 aaagaagcct ttcaagcttt aaccgacctg catgagatag gactagaagg gaagctttcg
    30841 gagccagaag ggcagagaaa ttttggtggc tttaattacc aagcctatct gaagactcag
    30901 ggaatttacc agactctcaa tatcaaaaca atccagtcac ttcaaaagat tggcagttgg
    30961 gatataggag aaaacttgtc cagtttacgt cgaaaggctg tggtttggat taagacgcac
    31021 tttccagacc ctatgcgcaa ttacatgaca ggactcttgc tgggacatct ggacaccgac
    31081 tttgaggaga tgaatgagct ttattccagt ctaggaatta tccacctctt tgccctatct
    31141 ggcatgcagg taggtttttt catgaatgga tttaagaaac ttctcttgca attgggcttg
    31201 acccaagaaa agttgaaatg gctgacttat cccttttccc ttatctatgc gggactaact
    31261 ggattttcag catcggttat tcgcagtctc ttgcaaaagc tactggctca acatggggtt
    31321 aagggcttgg ataattttgc cttgacggtg cttgtcctct ttattgtcat gccaaacttt
    31381 ttcttgacag caggaggagt cttgtcctgc gcttatgctt ttatcctgac catgaccagc
    31441 aaagaagggg aggggctcaa ggctgttgct agtgaaagtc tagtcatctc cttgggcata
    31501 ttgcccattc tatccttcta ttttgcggaa tttcaacctt ggtctatcct tttgaccttt
    31561 gtcttttcct ttctatttga cttgaccttc ttaccgctct tgtctatttt atttgtcctt
    31621 tcctttctct atccagtcat tcagctgaac tttatctttg aatggttgga gggcattatt
    31681 cgcttggtgt cacaggtgac aagtagacct ctggtctttg gacaacccaa tgcatggttt
    31741 ttaatcctat tgttaatttc cttggctttg gtctatgatt tgagaaaaaa cattaaaaag
    31801 ctaacggtat tgtgcttatt gattacaggg ctctttctcc tgaccaagca tccactggaa
    31861 aatgaaatca ccatgctgga tgtggggcaa ggagaaagta ttttcctacg ggatgtaact
    31921 gggaaaacca ttctcataga tgtaggtggt aaggcagaat cttataagaa aatcgaaaaa
    31981 tggcaagaaa agatgacgac cagcaatgcc cagcgaacct tgattcccta tctcaaaagt
    32041 cgaggagtag ttaagattga ccagctaatt ttgactaaca cggacaagga gcatgttgga
    32101 gatttgtcag aggtgactaa ggctttccat gtaggggaga ttctagtatc aaaagacagt
    32161 ctgaaacaga aggaatttgt ggcagaacta caggtgactc aaacaaaggt gcgtagtatg
    32221 acagtagggg agtacttgcc cattttcgga agtcagttag aagtcctatc tccaagggaa
    32281 attggatatg gaggtcatga agattccctg gttctttatg ggaaactctt gaataatcac
    32341 tttctcttca taggaaattt ggaggagaaa ggagagaagg acttgctgaa gtattatcca
    32401 gacttgaaag taaatgtttt gaaagctagc caacatggca ataaaaaatc atcaagtcca
    32461 gcctttctag aaaaactcaa accagagctt actcttatct cagttggaaa gagcaatcga
    32521 atgaaactcc cccatcagga aacattgaca cgactggaag gtatcaatag caaagtttat
    32581 cgaactgacc agcaaggagc tatacgtttt aaggggttgg atagttggaa aatcgaaagt
    32641 gttcgatagg aaggataaat gttgtagatt agtgaaataa actaaaaatt tgttgcataa
    32701 taatgataaa aatggtataa tgaaaacgta ttcaatattg aggatataaa atcattaaaa
    32761 atcagcaaaa gttgttttat tagttagttt ataatctatt ggtcttcttc agtccagtgt
    32821 atctgctgtg acagccacta aaagttacaa gtatgattgg aatacggttt tggaatatag
    32881 taccaactat cacgaccatc agtatgcttg gattccggaa tggtctcgtt attacagcta
    32941 ttctgagtat aaagttggcg gaggctggaa ctacgctcgt tatgaggtca taaactacta
    33001 tactggaggt tattaatcct taaagagtga gaaaaggagg gctggatatg ttaaatctta
    33061 ctcatgttac cttaaaaacg cgacaagtca tcttgcaaga tgcggatttt acctttaaaa
    33121 agggtaggat ttatggcctt cttgctatca atggctcggg aaagacgaca ctattccgag
    33181 ctatgagcaa gttgcttccc cttagtagtg gacacatcgc agttcctcct tctttgtttt
    33241 attatgagag cgttgaatgg ctggatggaa acttaagtgg gatggactac cttcgtctca
    33301 taaaaaacat ctggaagtca gacctaaact tgagagatga aatcgcctac tgggaaatgg
    33361 ctgactatat cagtcttccc atccgcaagt attccttagg gatgaagcaa cgcttggtga
    33421 ttgctatgta ttttctcagt caggccaaat gctggctcat ggatgagatt acaaatggct
    33481 tagacgagta ttatcgacag aagttttttg ataggctagc acaaatcgat agacaagaac
    33541 agctggttct tttaagttcc cactataagg aagagttggt tgatatctgc gatagagtag
    33601 taaccattca tcaggggcag atagaagagg tttagtttat gaaagatgtt agtctatttt
    33661 tattgaaaaa agttttcaaa agtcgtttaa actggattat cttactttta tttgcatctg
    33721 tactcggtgt taccttttat ttaaatagtc agactgcaaa ctcacacagc ttggagagca
    33781 ggttggaaag tcgcattgca gccaacgaga gggctatcaa tgaaaatgaa gagaaactct
    33841 cccaaatgtc tgataccagc tcggaggaat accagtttgc taaaaataat ttagacgtgc
    33901 aaaaaaatct tttgacgcga aagacagaaa ttctaacttt actaaaagaa gggcgctgga
    33961 aagaagccta ctatctgcag tggcaagatg aagagaagaa ttatgaattt gtatcaaatg
    34021 acccgactgc tagctctggc ttaaaaatgg gggttgaccg cgaacggaag atttaccaag
    34081 ccctgtatcc cttgaacata aaagcacata ctttggagtt tccgacccac gggattgatc
    34141 agattgtctg gattttagag gttatcatcc caagcttgtt tgtggttgcg attattttta
    34201 tgctaacaca actatttgca gaaagatatc aaaatcatct ggacacagct cacttatatc
    34261 ctgtttcaaa agtgacattt gcaatatcct ctcttagagt tggagtggga tatgtaactg
    34321 tgctgtttat cggaatctgt ggcttttctt ttctagtggg aagtctgata agtggttttg
    34381 gacagttaga ttatccctac ccaatttata gcttagtgaa tcaagaagta actattggga
    34441 aaatacaaga tgtattattt cctggcttgc tcttagcttt cttagccttt atcgtcattg
    34501 tggaagttgt gtacttgatt gcttactttt tcaagcaaaa aatgcctgtc ctctttcttt
    34561 cactcattgg gattgttggc ttattgtttg gcatccaaac aattcagcct cttcaaagga
    34621 ttgcacatct gattcccttt acttacttgc gttcagtgga gattttatct ggaagattat
    34681 ctaagcagat tgataatgtc gatctaaatt ggagcatggg gatggtctta cttccttgcc
    34741 tgattatcct tttgttagtg gggattctat ttatcgaaag atggggaagt tcacgtaaaa
    34801 aggaagtttt taaagtttag ttttcctata gggaagctaa agaaaaacta acatagggag
    34861 agaatcaact tggttctctc tttttgattc gaaaaccaaa ccaaaatata aacacaaact
    34921 tttcaaaaaa taacttttta tcttgacaag agctagaaaa cttggtatca tataaaagtt
    34981 gagaaaagca gaagtgagag cttctcgcct tgtgacatta agttgcctgg ccctacggat
    35041 gaaaagtttc gaagaaacgc tatcataacg tgcgggcttg tatatttacg agtccgctat
    35101 tgtttttctc taataaaaca aaagaggtga aaaccatagc aaagcaagac ttattcatca
    35161 atgatgagat tcgtgtacgt gaagttcgct tgattggtct tgagggagaa cagctaggca
    35221 tcaagccact cagtgaagcg caagctttgg ctgataacgc taatgttgac ctagtattga
    35281 ttcaacccca agccaaaccg cctgttgcaa aaattatgga ctacggtaag ttcaaatttg
    35341 agtaccagaa gaagcaaaaa gaacaacgta aaaaacaaag cgttgttact gtgaaagaag
    35401 ttcgtctaag tccaactatt gacaagggtg actttgatac aaaacttcgt aatgcacgta
    35461 agttccttga aaaaggaaat aaagttaagg tatctattcg ctttaagggt cgtatgatta
    35521 cccataaaga gattggtgca aaagttttag ccgagtttgc tgaagcaact caagatattg
    35581 ccatcatcga acaacgtgct aaaatggatg gacgtcaaat gttcatgcaa ttggcgccag
    35641 cgactgacaa aaaataattg tcagaaagtt aaataaagga gaaaaaatca tgccaaaaca
    35701 aaaaacacac cgcgcatcag ctaaacgttt caaacgtaca ggttctggtg gacttaaacg
    35761 tttccgtgct tacacttctc accgtttcca cggaaaaacc aagaaacaac gtcgtcatct
    35821 tcgtaaagca tctatggtgc attcaggaga ttacaaacgt atcaaagcaa tgcttactcg
    35881 cttgaaataa tagcttgact gtaagtaaac aattctagga aatatttgga ggaaataaaa
    35941 tatggcacgt gttaaaggtg gcgttgtatc acgcaaacgt cgtaaacgta ttcttaaatt
    36001 agcaaaaggt tactatggag ctaaacacat cttgttccgt actgcaaaag aacaagtaat
    36061 gaactcttac tactatgcat accgtgaccg tcgtcagaaa aaacgtgact tccgcaaatt
    36121 gtggattact cgtatcaatg cggcagctcg tatgaacgga ctttcatact cacaattgat
    36181 gcatggtttg aaattggctg agatcgaagt taaccgtaaa atgcttgctg acttggctgt
    36241 taacgatgca gtagctttca cagctcttgc agatgcagct aaagcaaaac ttggtaaata
    36301 acaactgatg agactggaac aggattgtcc agtcttttta aaaataaagg agaaagatat
    36361 ggcttcaaaa atgctacaca cttgcttacg agtagaaaat cttgaaaaat caatcgcatt
    36421 ttatcaagat gcttttggtt ttaaagaatt gcgtcgcaga gattttccag accatgcctt
    36481 cacgattgtc tatctaggtc ttgagggtga tgattatgag ttggagttga cttataacta
    36541 cgatcacggt ccgtatgtgg ttggtgatgg gtttgcccat atcgccctca gtacacctga
    36601 tcttgaggca cttcatcaag aacacagtgc aaaaggctat gaagtgactg agccaaatgg
    36661 tctaccagga actacaccaa actattactt tgttaaagac cctgatggat ataaggtcga
    36721 agtcattcgt gaaaaataat ttcgtgcaag ttaagtagaa tattcgtttt ctacttgact
    36781 ttttttagct gaaagagtat actaataaaa attcaacctt taaggggagt ccagagagac
    36841 tcacaaggtg tcagataaaa gaatagtgca attttctaga ggagactttt tgagtgtgct
    36901 ctcttgtgtt gtacgatttt aactgaggcc ttgcactagc aaggtctttt ctttatctgg
    36961 tccccttaaa atttaaggag gaaaagttat gaatctcaca tgtaagaagc gtttgggtgt
    37021 cattcggttg gaaaccatga aggtggttgc acaagaggaa atcgcgccag caatctttga
    37081 attagtccta gaaggagaaa tggttgaagc catgcgagca ggccaatttc ttcatctgcg
    37141 tgtaccggac gatgcccatc tcttacgtcg tcctatttca atttcgtcta ttgacaaggc
    37201 aaacaagcag tgtcacctca tttatcggat tgagggagct gggactgcaa ttttttcaac
    37261 cttaagtcag ggagacactc ttgatgtgat ggggcctcag ggaaatggtt ttgacttgtc
    37321 tgaccttgat gagcagaatc aggttctcct tgttggtggt gggattggtg ttccaccctt
    37381 gcttgaggtg gccaaggaat tgcatgaacg tggagtgaaa gtagtgacag tcctcggttt
    37441 tgctaataag gatgctgtta ttttgaaaac ggaattggct cagtatggtc aggtctttgt
    37501 aacgacagat gatggttctt atggcatcaa gggaaatgtt tccgttgtta tcaatgattt
    37561 agatagtcag tttgatgctg tttactcgtg tggggctcca ggaatgatga agtatatcaa
    37621 tcaaaccttt gatgatcacc caagagccta tttatctctg gaatctcgta tggcttgtgg
    37681 gatgggagct tgctatgcct gtgttctaaa agtaccagaa agcgagacgg tcagccaacg
    37741 cgtctgtgaa gatggtcctg ttttccgcac aggaacagtt gtattataag gagaaaatta
    37801 tgactacaaa tcgattacaa gtgtctctac ctggtttgga tttgaaaaat ccgattattt
    37861 cagcatcagg ctgttttggc tttggacaag agtatgccaa gtactatgat ttagaccttt
    37921 taggttctat tatgatcaag gcgacaaccc ttgaaccacg ttttgggaat ccaactccaa
    37981 gagtggcaga gacgcctgct ggtatgctca atgcaattgg cttgcaaaat cctggtttag
    38041 aggttgtttt ggctgaaaag ctaccttggc tggaaagaga atatccaaat cttcctatta
    38101 ttgccaatgt agctggtttt tcaaaacaag agtatgcagc tgtttctcat gggatttcca
    38161 aggcaactaa tgtaaaagct atcgagctca atatttcttg tcccaatgtt gaccactgta
    38221 atcatggact tttgattggt caagatccag atttggctta tgatgtggtg aaagcagctg
    38281 tggaagcctc agaagtgcca gtttatgtca aattaacccc gagtgtgacc gatatcgtta
    38341 ctgtcgcaaa agctgcagaa gatgcgggag caagtggctt aactatgatc aatactctgg
    38401 ttggaatgcg ctttgacctc aaaactagaa aaccaatctt ggccaatgga acaggtggaa
    38461 tgtctggtcc agcaatcttt ccagtagccc tcaaactcat ccgccaagtt gcccaaacaa
    38521 cagacctgcc tatcattgga atgggaggag tggattcggc tgaagctgcc ctagaaatgt
    38581 atctggctgg ggcatctgct atcggagttg gaacagctaa ctttaccaat ccttatgcct
    38641 gccctgacat catcgaaaat ttaccaaaag tcatggataa atacggtatt agcagtctgg
    38701 aagaactccg tcaggaagta aaagagtctc tgaggtaaac tgcaatcaat ctgttcttga
    38761 ttttttatta gtttgtaata tgaatttagg agaattttgg tacaataaaa taaataagaa
    38821 cagaggaaga aggttaatga agaaagtaag atttattttt ttagctctgc tatttttctt
    38881 agctagtcca gagggtgcaa tggctagtga tggtacttgg caaggaaaac agtatctgaa
    38941 agaagatggc agtcaagcag cgaatgagtg ggtttttgat actcattatc aatcttggtt
    39001 ctatataaaa gcagatgcta actatgctga aaatgaatgg ctaaagcaag gtgacgacta
    39061 tttttacctc aaatctggtg gctatatggc caaatcagaa tgggtagaag acaagggagc
    39121 cttttattat cttgaccaag atggaaagat gaaaagaaat gcttgggtag gaacttccta
    39181 tgttggtgca acaggtgcca aagtaataga agactgggtc tatgattctc aatacgatgc
    39241 ttggttttat atcaaagcag atggacagca cgcagagaaa gaatggctcc aaattaaagg
    39301 gaaggattat tatttcaaat ccggtggtta tctactgaca agtcagtgga ttaatcaagc
    39361 ttatgtgaat gctagtggtg tcaaagtaca gcaaggttgg ctttttgaca aacaatacca
    39421 atcttggttt tacatcaaag aaaatggaaa ctatgctgat aaagaatgga ttttcgagaa
    39481 tggtcactat tattatctaa aatccggtgg ctacatggca gccaatgaat ggatttggga
    39541 taaggaatct tggttttacc tcaagtttga tggcaaaatg gctgaaaaag aatgggtcta
    39601 cgattctcat agtcaagcct ggtactactt caaatccggt ggttacatga cagccaatga
    39661 atggatttgg gataaggaat cttggtttta tcttaaatct gatgggaaaa tagctgaaaa
    39721 agaatgggtc tacgattctc atagtcaagc ttggtactac ttcaaatccg gtggttacat
    39781 gacagccaat gaatggattt gggataagga atcttggttt tacctcaaat ctgatgggaa
    39841 aatagctgaa aaagaatggg tctacgatta tcatagtcaa gcctggtact acttcaaatc
    39901 tggtggctac atggcgaaaa atgagacagt agatggttat cagcttggaa gcgatggtaa
    39961 atggcttgga ggaaaagcta caaatgaaaa tgctgcttac tatcaagtag tgcctgttac
    40021 agccaatgtt tatgattcag atggtgaaaa gctttcctat atatcgcaag gtagtgtcgt
    40081 atggctagat aaggatagaa aaagtgatga caagcgcttg gctattacta tttctggttt
    40141 gtcaggctat atgaaaacag aagatttaca agcgctagat gctagtaagg actttatccc
    40201 ttattatgag agtgatggcc accgttttta tcactatgtg gctcagaatg ctagtatccc
    40261 agtagcttct catctttctg atatggaagt aggcaagaaa tattattcgg cagatggcct
    40321 gcattttgat gattttaagc ttgagaatcc cttccttttc aaagatttaa cagaggctac
    40381 aaactacagt gctgaagaat tggataaggt atttagtttg ctaaacatta acaatagcct
    40441 tttggagaac aagggcgcta cttttaagga agccgaagaa cattaccata tcaatgctct
    40501 ttatctcctt gcccatagtg ccctagaaag taactgggga agaagtaaaa ttgccaaaga
    40561 taagaataat ttctttggca ttacagccta tgatacgacc ccttaccttt ctgctaagac
    40621 atttgatgat gtggataagg gaattttagg tgcaaccaag tggattaagg aaaattatat
    40681 cgatagggga agaactttcc ttggaaacaa ggcttctggt atgaatgtgg aatatgcttc
    40741 agacccttat tggggcgaaa aaattgctag tgtgatgatg aaaatcaatg agaagctagg
    40801 tggcaaagat tagtactata agtgaatatg atttgagtga atagtaagtt aaaaatcctg
    40861 atttcaagta aaatcaggat tttttcatgg atgcaatttt tttggagtct ggtgtgacgc
    40921 ggagggtctt ttgtcctgtg taagtgacaa agccgggttt tccaccagtt ggtttattga
    40981 gttttttgac ttcaatcata tctacctgca ccagattcga caggcgccct tgagagaagt
    41041 aggcagctaa ctctgctgcg tctgtcttga ctgcatcaga tgggtcaaga tttcctgaga
    41101 tgacaacatg gcttccagga atgtccttag catggaacca aagttcctcc ttgcgggcca
    41161 ttttaaaggt caattcctca ttttgaagat tgtttcgtcc gacatagatg atggttttgc
    41221 catcgcttgc tagatattgt tctagttttt tgcgtttctg gattttctcc cgttgtcttc
    41281 tgcggataaa acctgtttga atcaattctt cacggatttc agcgatttct tccagtccag
    41341 cttggttgag gacggtttct acactttcca gatagagaat agtggctttg gtttcttcaa
    41401 tcaaatcagt caagtatttg acagcttctt tgagtttctg ataccgttta aaatagcgtt
    41461 gggcattctg gttgggagtc agagccttat caagcgcaat catgataggt tggttggtat
    41521 agtagttgtc taggataacc tggtcttggt cgttaggcac ttggtggagg aaggttgtca
    41581 gcaattctcc tttttgacga aattcttcag cgttgtctgt cgccagtaac tctttttcct
    41641 gttttttgag tttgtgtcgg tttttctgaa gttcattttc aacacgacga atcagttcac
    41701 tggcctgttg tttgacgcgg tcgcgctcag ccttattctt atagtaggtg tccaacaaat
    41761 cagaaagatt tgcaaaaggc tctcccgcct gatttgcaaa aggaactgga ctgaaggaag
    41821 tctcagtcaa gcatggcttg gtttcttgat tgaaaaaatt tcggaaagcg gaaagttttt
    41881 cactaaccag tatcctttcc aattcatttg ccgtatcgcg tcccagacct tgaaagaggc
    41941 tttgaagatt ttttgctgtt agttcttggg tttgcaggat ttcaaagagc ttttcatcct
    42001 tgatagtaaa aggattgaga gattctgtac ttggcggagc gatataggtc gatcctggaa
    42061 gtaaggtgcg gtagctattt tgtgaaaaac cgacgtgttt gataacttcg aggattttat
    42121 gactgctttt atcgaccagt agaatattac tgtgtttccc cataatttcg ataatcaagg
    42181 tagcctggat atggtctcca atctcgtttt tattggaaac tgtcatttcc acaatacggt
    42241 cattttccac ttgctcaatc gactcaatca gggccccctg caaatacttt ctcaaaacca
    42301 tgataaaggt agaaggttgg gctggatttt caaaagtcgt ttgggtcagc tgaatgcgtc
    42361 caaaaactgg atgggcagaa aggagcaggc gatggctttg gcgattgctg cggatttgca
    42421 agaccaactc ttgttcaaaa ggctgattga ttttctggat gcgaccattc actaattcgc
    42481 ttcgcaattc ctcaactatg tggtgtaaaa aaaatccgtc aaatgacatc gttctctcct
    42541 tgtgattgta ttccatagta ttatatcaaa aaggtagaat aaaatcatgg aaatgtggta
    42601 taataaagcc aagtaaagag aaacgagaag cacatgtata ttgaaatggt agatgaaact
    42661 ggtcaagttt caaaagaaat gttgcaacaa acccaagaaa ttttggaatt tgcagcccaa
    42721 aaattaggaa aagaagacaa ggagatggca gtcacttttg tgaccaatga gcgtagtcat
    42781 gaacttaatc tggagtaccg tgacaccgac cgtccgacag atgtcatcag ccttgagtat
    42841 aaaccagaat tggaaattgc ctttgacgaa gaggatttgc ttgaaaatcc agaattggca
    42901 gagatgatgt ctgagtttga tgcctatatt ggggaattgt tcatctctat cgataaggct
    42961 catgagcagg ccgaagaata tggtcacagc tttgagcgtg agatgggctt cttggcagta
    43021 cacggctttt tacatattaa cggctatgat cactatactc cggaagaaga agcggagatg
    43081 ttcggtttac aagaagaaat tttgacagcc tatggactca caagacaata aacgaaaatg
    43141 gaaaaatcgt gacttgatat ccagtttaga atttgctttg acaggtattt ttactgctat
    43201 caaggaagaa cgcaatatgc gaaaacacgc agtgacggct ctagtggtca tccttgcagg
    43261 ttttgttttt caggtgtcac gaatcgaatg gctctttctc ctattgagca ttttcttggt
    43321 agtagccttt gagattatca actctgctat tgaaaatgtg gtggatttgg ccagtcacta
    43381 tcacttttcc atgctggcta aaaatgccaa ggatatggcg gctggcgcgg tattagtggt
    43441 ttctcttttt gcagccttaa caggcgcatt gatttttctc ccacgaatct gggatttatt
    43501 attttaaaca gtaagaggaa attatgactt ttaaatcagg ctttgtagcc attttaggac
    43561 gtcccaatgt tgggaagtca acctttttaa atcacgttat ggggcaaaag attgccatca
    43621 tgagtgacaa ggcgcagaca acgcgcaata aaatcatggg aatttacacg actgataagg
    43681 agcaaattgt ctttatcgac acaccaggga ttcacaaacc taaaacagct ctcggagatt
    43741 tcatggttga gtctgcctac agtacccttc gcgaagtgga cactgttctt ttcatggtgc
    43801 ctgctgatga agcgcgtggt aagggggacg atatgattat cgagcgtctc aaggctgcca
    43861 aggttcctgt gattttggtg gtgaataaaa tcgataaggt tcatccagac cagctcttgt
    43921 ctcagattga tgacttccgt aatcaaatgg actttaagga aattgttcca atctcagccc
    43981 ttcagggaaa taacgtgtct cgtctagtgg atattttgag tgaaaatctg gatgaaggtt
    44041 tccaatattt cccgtctgat caaatcacag accatccaga acgtttcttg gtttcagaaa
    44101 tggttcgcga gaaagtcttg catctaactc gtgaagagat tccgcattct gtagcagtag
    44161 ttgttgactc tatgaaacga gacgaagaga cagacaaggt tcacatccgt gcaaccatca
    44221 tggtcgagcg cgatagccaa aaagggatta tcatcggtaa aggtggcgct atgcttaaga
    44281 aaatcggtag catggcccgt cgtgatatcg aactcatgct aggagacaag gtcttcctag
    44341 aaacctgggt caaggtcaag aaaaactggc gcgataaaaa gctagatttg gctgacttgg
    44401 gctataatga aagagaatac taagtagagg taggctcatg cctgcttctt gtttttacag
    44461 aaggaggact tatgcctgaa ttacctgagg ttgaaaccgt ttgtcgtagc ttagaaaaat
    44521 tgattatagg aaagaagatt tcgagtatag aaattcgcta ccccaagatg attaagacgg
    44581 atttggaaga gtttcaaagg gaattgccta gtcagattat cgagtcaatg ggacgtcgtg
    44641 gaaaatattt gcttttctgc ctgacagaca aggtcttgat ttcccatttg cggatggagg
    44701 gcaagtattt ttattatcca gaccaagtgc ctgaacgcaa gcatgcccat gttttcttcc
    44761 ggtttgaaga tgggggcacg cttgtttatg aggatgtacg caagtttgga accatggaac
    44821 tcttggtgcc tgacctttta gacgcctact ttatttctaa aaaattaggt cctgaaccaa
    44881 gcgaacaaga ctttgattta caggtctttc aagctgccct tgccaagtcc aaaaagccta
    44941 tcaaatccca tctcctagac cagaccttgg tagctggact tggcaatatc tatgtggatg
    45001 aggttctctg gcgagctcag gttcatccag ctagaccttc ccagactttg acagcagaag
    45061 aagcgactgc cattcatgac cagaccattg ctgttttggg ccaggctgtt gaaaaaggcg
    45121 gttccaccat tcggacctat accaatgcct ttggggaaga tggaagcatg caggattttc
    45181 atcaggtcta tgataagact ggtcaagaat gtgtacgctg tggtaccatc attgagaaaa
    45241 ttcaactagg cggacgaggc acccactttt gtccaaactg tcaaaggagg gactgatgag
    45301 aaaaatcatc ggaatcactg ggggaattgc ctctggtaag tcaactgtga caaattttct
    45361 aagacagcaa ggctttcaag tagtggatgc cgacgcagtc gtccaccaac tacagaaacc
    45421 tggtggtcgt ctgtttgagg ctctagtaca gcactttggg caagaaatca ttcttgaaaa
    45481 cggagaactc aatcgccctc tcctagctag tctcatcttt tcaaatcctg aagagcaaaa
    45541 atggtctaag caaattcaag gggagattat ccgtgaggaa ctggctactt tgagagaaca
    45601 gttggctcag acagaagaga ttttcttcat ggatattccc ctactttttg agcaggacta
    45661 cagcgattgg tttgctgaga cttggttggt ctatgtggac cgagatgccc aagtagaacg
    45721 cttaatgaaa agggaccagt tgtccaagga tgaagctgag tctcgtctgg cagcccagtg
    45781 gcctttagaa aaaaagaaag atttggccag ccaggttctt gataataatg gcaatcagaa
    45841 ccagcttctt aatcaagtgc atatccttct tgagggaggt aggcaagatg acagagatta
    45901 actggaagga taatctgcgc attgcctggt ttggtaattt tctgacagga gccagtattt
    45961 ctttggttgt accctttatg cccatcttcg tggaaaatct aggtgtaggg agtgagcaag
    46021 tcgcttttta tgcaggctta gcaatttctg tctctgctat ttccgcggcg ctcttttctc
    46081 ctatttgggg tattcttgct gacaaatacg gccgaaaacc catgatgatt cgggcaggtc
    46141 ttgctatgac tatcactatg ggaggcttgg cctttgtccc aaatatctat tggttaatct
    46201 ttcttcgttt actaaacggt gtatttgcag gttttgttcc taatgcaacg gcactgatag
    46261 ccagtcaggt tccaaaggag aaatcaggct ctgccttagg tactttgtct acaggcgtag
    46321 ttgcaggtac tctaactggt ccctttattg gtggctttat cgcagaatta tttggcattc
    46381 gtacagtttt cttactggtt ggtagttttc tatttttagc tgctattttg actatttgct
    46441 ttatcaagga agattttcaa ccagtagcca aggaaaaggc tattccaaca aaggaattat
    46501 ttacctcggt taaatatccc tatcttttgc tcaatctctt tttaaccagt tttgtcatcc
    46561 aattttcagc tcaatcgatt ggccctattt tggctcttta tgtacgcgac ttagggcaga
    46621 cagagaatct tctttttgtc tctggtttga ttgtgtccag tatgggcttt tccagcatga
    46681 tgagtgcagg agtcatgggc aagctaggtg acaaggtggg caatcatcgt ctcttggttg
    46741 tcgcccagtt ttattcagtc atcatctatc tcctctgtgc caatgcctct agcccccttc
    46801 aactaggact ctatcgtttc ctctttggat tgggaaccgg tgccttgatt cccggggtta
    46861 atgccctact cagcaaaatg actcccaaag ccggcatttc gagggtcttt gccttcaatc
    46921 aggtattctt ttatctggga ggtgttgttg gtcccatggc aggttctgca gtagcaggtc
    46981 aatttggcta ccatgctgtc ttttatgcga cgagcctttg tgttgccttt agttgtctct
    47041 ttaacctgat tcaatttcga acattattaa aagtaaagga aatctagtgc gagtaaaaat
    47101 taatctcaaa tgctcctctt gtggcagtat caattaccta accagtaaaa attcaaaaac
    47161 ccatccagac aagattgagg ttttaaagta ttgtcccaag gaaagaaaag taaccctaca
    47221 tcttgaatct aagtagattt tatggtaaaa taatagggat tttaaggagt ttgatatgta
    47281 taacctatta ttaaccattt tattagtatt atctgttgtg attgtgattg caattttcat
    47341 gcaaccaacc aaaaaccaat ccagcaatgt atttgatgcc agttcaggtg atttgtttga
    47401 acgcagtaaa gctcgcggtt ttgaagctgt aatgcagcgt ttgacaggga ttttagtctt
    47461 tttctggcta gccattgcct tagcattgac ggtattatca agtagataag aaaataatgg
    47521 gcaggactag gtctttgcct ctttttattt ttaaaggatg tttgagaagg ttttacagta
    47581 aaagaaaatt aaaaaatcta gaaagaaaat atgaaagata gaataaaaga atatttacaa
    47641 gacaagggaa aggtgactgt taatgatttg gctcaggctt tgggaaaaga cagttccaag
    47701 gattttcgtg agttgattaa aaccttgtcc ttaatggaaa gaaagcacca aattcgtttt
    47761 gaagaagatg gtagtctgac attagaaatt aagaaaaaac atgagattac cctcaagggg
    47821 atttttcatg cccataaaaa tggctttggc tttgttagtc tggaaggcga ggaggacgac
    47881 ctttttgtag ggaaaaatga tgtcaactat gctattgatg gtgataccgt cgaggtagtg
    47941 attaagaaag tcgctgaccg caataaggga acagcagcag aagccaaaat tattgatatc
    48001 ctagaacaca gtttgacaac agttgtcggg caaatcgttc tggatcagga aaaacctaag
    48061 tatgctggct atattcgttc aaaaaatcag aaaatcagtc aaccgattta tgttaagaaa
    48121 ccagccctaa aattagaagg aacagaagtt ctcaaggtct ttatcgataa atacccaagc
    48181 aagaaacatg atttctttgt cgcgagtgtt ctcgatgtgg tgggacactc aacggatgtc
    48241 ggaattgatg ttcttgaggt tttggaatca atggacattg tatccgagtt tccagaagct
    48301 gttgttaagg aagcagaaag tgtgcctgat gctccgtctc aaaaggatat ggaaggtcgt
    48361 ctggatctaa gagatgaaat tacctttacc attgacggtg cggatgccaa ggacttggac
    48421 gatgcagtgc atatcaaggc tctgaaaaat ggcaatctgg agcttggggt tcacatcgca
    48481 gatgtttctt attatgtgac cgaggggtct gcccttgaca aggaagccct taaccgtgcg
    48541 acttctgttt acgtgacaga ccgagtggtg ccaatgcttc cagaacgact atcaaatggc
    48601 atctgctctc tcaatcccca agttgaccgc ctgacccagt ctgctattat ggagattgat
    48661 aaacatggtc gtgtggtcaa ctataccatt acacaaacag ttatcaagac cagttttcgt
    48721 atgacctata gcgatgtcaa tgatatccta gctggcgatg aagaaaagag aaaaaaatat
    48781 cataaaattg taccaagtat cgaactcatg gccaagcttc atgaaacttt agaaaacatg
    48841 cgtgtgaaac gtggagctct caattttgat accaatgaag cgaagatttt agtggataaa
    48901 caaggtaagc ctgttgatat cgttcttcgg cagcgtggta ttgccgagcg gatgattgag
    48961 tcttttatgt tgatggctaa tgaaacagtt gccgaacatt tcagcaagtt ggatttgcct
    49021 tttatctatc gaattcacga ggagcctaag gctgaaaagg ttcagaagtt tattgattat
    49081 gcttcgagtt ttggcttgcg catttatggg actgccagtg agattagtca ggaggcactt
    49141 caagacatca tgcgtgctgt tgagggagaa tcttatgcag atgtattgtc catgatgctt
    49201 cttcgctcta tgcagcaggc tcgttattcg gagcacaatc acggccacta tggactagct
    49261 gctgactatt atactcactt taccagtcca attcgtcgtt atccagacct tcttgttcac
    49321 cgtatgattc gggattacgg ccgttctaag gaaatagcag agcattttga acaagtgatt
    49381 ccagagattg cgacccagtc ttccaaccgt gaacgtcgtg ccatagaagc tgagcgtgaa
    49441 gtcgaagcca tgaaaaaggc tgagtatatg gaagaatacg tgggtgaaga gtatgatgca
    49501 gttgtatcaa gtattgtcaa attcggtctc tttgtcgaat tgccaaacac agttgaaggc
    49561 ttgattcaca tcactaatct acctgaattt tatcatttca atgagcgtga tttgactctt
    49621 cgtggagaaa aatcaggtat cactttccga gtgggtcagc agatccgtat ccgtgttgaa
    49681 agagcggata aaatgactgg agagattgat ttttcattcg tacctagtga gtttgatgtg
    49741 attgaaaaag gcttgaaaca gtctagtcgt agtggcagag ggcgtggttc aaatcgtcgt
    49801 tcggataaga aggaagacaa gagaaaatca ggacgctcaa atgataagcg taagcattca
    49861 caaaaagaca agaagaaaaa aggaaagaaa cctttttaca aggaagtagc taagaaagga
    49921 gccaagcatg gcaaagggcg agggaaaggt cgtcgcacaa aataaaaagg cacgccacga
    49981 ctatacaatc gtagatacgc tagaggcagg gatggtcctg actggaactg aaatcaagag
    50041 tgtacgagct gctcgaatta atctcaagga tggctttgct caagtgaaaa atggagaagt
    50101 ttggctgagc aatgttcata tcgcgcctta cgaagagggc aatatctgga accaggaacc
    50161 agaacgtcgt cgtaaactcc tgctccataa aaggcaaatt caaaaattgg aacaagagac
    50221 caaagggaca ggaatgacct tagttcccct taaggtctat ataaaagatg gctacgctaa
    50281 gcttctttta ggacttgcca aagggaagca tgactatgac aaacgggagt ctatcaaacg
    50341 tcgtgagcaa aatcgagata tcgcgcgtgt gatgaaagct gttaatcagc gataaaaaga
    50401 ggaattgaaa atggaaaaat tagttgccta taaacgcatg cctttgtgga ataaacaaac
    50461 aatgcctgaa gctgttcagc aaaagcacaa tacaaaagtt gggacttggg ggaaaattac
    50521 tgtcttgaag ggagctctca agtttattga attgacagaa gaaggggaag ttctagctga
    50581 acacctcttt gaagcagggg cagacaatcc aatggcccaa cctcaagcct ggcaccgagt
    50641 ggaagctgcc acagatgatg tggaatggta cttggaattt tattgtaaac ctgaggatta
    50701 ttttgctaaa aaatacaata ccaatcctgt tcattcagag gtcctagagg tcatggagac
    50761 agtgaaacaa gggaaagctt tggatttggg ttgtggtcag gggcgtaatt ctctttttct
    50821 agcccagcaa gattttgatg tgacggctgt agatcaaaat ggactagctc ttgaaatctt
    50881 gcaaagcatt gtggagcagg aagatttgga catgcctgtt ggcctttacg atatcaattc
    50941 agctagcatt gaacaagaat atgattttat cgtttcaaca gttgttctca tgtttctaca
    51001 agcggaccgc attccagcta ttattcaaaa tatgcaggag aaaaccagtg ttggtggtta
    51061 caaccttatc gtttgtgcca tggacacgga ggattatcct tgctcggtta acttcccatt
    51121 cacctttaaa gaaggagaac tggcagacta ttacaaggat tgggaattgg ttaagtacaa
    51181 tgaaaatcca ggccatttgc atcgtcgcga tgagaatggc aatcgtattc aactacgctt
    51241 tgcgacctta ctagctaaga aaatcaagta aacacacatg aagattagga attttcctga
    51301 tcttttttct tttttacgaa tgatatagaa aaggagggaa ttcatgtttg ttgcgagaga
    51361 tgctagggga gaattggtaa atgtgttaga ggataaactt gagaagcaag catacacctg
    51421 cccagcttgt ggaggccagc tccatttgcg tcaaggacca agtgtacgga cgcattttgc
    51481 ccataaatcc ttaaaagact gtgatttttt ctttgaaaat gaaagtccag aacacctggc
    51541 caataaggaa tccctctatc actggttgaa aaaagagaca aaggttcaat tagagtaccc
    51601 gctttcagaa cttaaacaga ttgcggatgt atttgtaaat ggcaatctag ctctagaagt
    51661 tcagtgtagt cccttgcctc agaaagtcct taaagagcga agtgagggct atcgtagtca
    51721 gggttaccaa gtactgtggt tgctgggtca aaaactgtgg ctcaaggagc gtttgactcg
    51781 tctacagcaa ggttttcttt atttcagtca aaacatgggc ttttatgttt gggaattaga
    51841 caaggaaaaa caagttttaa gactcaaata cctgatttac caggatctcc gcggtaaact
    51901 ccattatcaa atcaaggaat tttcctatgg tcaaggtagt ttattggaaa tattgcgtct
    51961 tccctataag agacaaaaaa tatctcattt tacagtttct gaggacaagg acatctgtcg
    52021 ctatatccgg caacaacttt attatcaaaa tctcttttgg atgaaagaac aagcagaagc
    52081 ctatcaaaag ggagaaaata tcctgactta tggactgaaa gaatggtatc cacaaattcg
    52141 accaatagtg ggcaaatttt tccagattga acaagacttg actagctatt atcagcactt
    52201 ttatacctat taccaaaaaa atcctcaaaa tgattggcaa aagctttatc caccagcctt
    52261 ttatcagcaa tatttcttga aaaatatggt agaatagaaa ggatggagga atctaatggt
    52321 attacaaaga aatgaaataa atgaaaaaga tacatgggat ctatcaacga tctacccaac
    52381 tgaccaggct tgggaagaag ccttaaaaga tttaacagaa caattggaga cagtagccca
    52441 gtatgaaggc catctcttgg atagtgcgga taacctacta gaaatcactg aattttctct
    52501 tgaaatggaa cgccagatgg agaagcttta cgtttatgct catatgaaga atgaccagga
    52561 tacacgtgaa gctaagtatc aagagtacta tgccaaggcc atgacactct acagccagtt
    52621 agaccaagcc ttttcattct atgatcctga atttatggag attagcgaaa agcagtatgc
    52681 tgacttttta gaagctcaac caaagctgca ggtttatcaa cactattttg acaagctctt
    52741 gcaaggcaag gatcacgttc tttcacaacg tgaagaagaa ttattggctg gagctggaga
    52801 aatctttggt tcagcaagtg aaaccttcgc tatcttggac aatgcggata ttgtgttccc
    52861 ttatgtccta gacgatgatg gtaaagaagt tcagctatct catgggactt acacacgttt
    52921 gatggagtct aaaaaacgtg aggttcgccg tggtgcctat caagctcttt atgcgactta
    52981 cgaacaattc caacacacct atgccaaaac cttgcaaacc aatgttaagg tgcaaaatta
    53041 ccgtgctaaa gttcgtaact acaagagtgc tcgtcatgca gctctcgcag cgaattttgt
    53101 tccagaaagt gtttatgaca atttggtagc agcagttcgc aagcatttgc cactcttaca
    53161 tcgctatctt gagcttcgtt caaaaatctt ggggatttca gatctcaaga tgtacgatgt
    53221 ctacacaccg ctttcatctg ttgaatacaa ttttacctac caagaagcct tgaaaaaagc
    53281 agaagatgct ttggcagtct tgggtgagga ttacttgagc cgtgtcaaac gtgccttcag
    53341 cgagcgttgg attgatgttt acgaaaatca aggcaagcgt tcaggtgcct actctggtgg
    53401 ttcttacgat accaatgcct ttatgcttct caactggcag gacaatctgg acaatctctt
    53461 tactcttgtt catgaaacag gtcacagtat gcattcaagc tatactcgtg aaacacagcc
    53521 ttatgtttac ggagattact ctatcttttt ggctgagatt gcctcaacta ccaatgaaaa
    53581 tatcttgacg gagaaattat tggaagaagt ggaagacgac gcaacacgct ttgctattct
    53641 caataacttc ctagatggtt tccgtggaac agttttccgc caaactcaat ttgctgagtt
    53701 tgaacacgcc attcaccaag cagatcaaaa tggggaggtc ttgacaagcg atttcctaaa
    53761 taaactctac gcagacttga accaagagta ttatggtttg agtaaggaag acaatcctga
    53821 aatccaatac gagtgggctc gcattccaca cttctactat aactactatg tatatcaata
    53881 ttcaactggc tttgcggccg cctcagcctt ggctgaaaaa attgtccatg gtagtcaaga
    53941 agaccgtgac cgctatatcg actacctcaa ggcaggtaag tcggactatc cacttaatgt
    54001 catgagaaaa gctggtgttg atatggagaa ggaagactac ctcaacgatg cctttgcagt
    54061 ctttgaacgc cgtttaaatg agtttgaagc ccttgttgaa aaattaggat tggcataaaa
    54121 tggttgaatc gtatagtaag aatgctaacc ataacatgcg tcgtcctgtc gtcaaagaag
    54181 aaattgtaga cttgatgcgt cagcgtcaaa agcaggtcac aggtttcttg aaagaattgg
    54241 aagactttgc ccgcaaggaa aatattccta ttattcccca tgaaacggtt gcttatttcc
    54301 gttttcttat ggaaaccatg cagcctaaaa atattctgga aattgggacg gctatcggtt
    54361 tttcagctct cttgatggct gaacatgcgc caaatgctaa gattacaact attgatcgta
    54421 atccagaaat gattggtttt gccaaggaaa attttgccca gtttgacagt cgcaagcaaa
    54481 tcactctcct agagggagat gcggtggatg tcttatctac actgacagag tcttatgatt
    54541 tcgtctttat ggattctgcc aagtctaaat acatcgtctt tctgccagaa atcctcaaac
    54601 atttggaagt tggtggtgtg gttgtcttgg atgatatttt tcaaggtggt gatgttgcca
    54661 aggatattat ggaagtccgt cgtggtcagc gaaccattta tcgaggcctt caaaaattat
    54721 ttgatgcaac cttagacaat ccagaactca ccgcaacatt agtgccttta ggagatggta
    54781 ttctcatgct tcgtaaaaat gtagcagatg ttcaactgtc tgaaagcgaa tgattttcag
    54841 aaaaatttaa gaaaaaatag taaaatagat agagtaacac ttatctcaaa ggagtagaca
    54901 tgaagaaaaa attattggca ggtgccatca cactattatc agtagcaact ttagcagctt
    54961 gttcgaaagg gtcagaagga gcagacctta tcagcatgaa aggggatgtc atcacagaac
    55021 atcaatttta tgagcaagtg aaaaacaacc cttcagccca acaagtcttg ttaaatatga
    55081 ccatccaaaa agtttttgaa aaacaatatg gctcagagct tgatgataaa gaggttgatg
    55141 atactattgc cgaagaaaaa aaacaatatg gcgaaaacta ccaacgtgtc ttgtcacaag
    55201 caggtatgac tcttgaaaca cgtaaagctc aaattcgtac aagtaaatta gttgagttgg
    55261 cagttaagaa ggtagcagaa gctgaattga cagatgaagc ctataagaaa gcctttgatg
    55321 agtacactcc agatgtaacg gctcaaatca tccgtcttaa taatgaagat aaggccaaag
    55381 aagttctcga aaaagccaag gcagaaggtg ctgattttgc tcaattagcc aaagataatt
    55441 caactgatga aaaaacaaaa gaaaatggtg gagaaattac ctttgattct gcttcaacag
    55501 aagtacctga gcaagtcaaa aaagccgctt tcgctttaga tgtggatggt gtttctgatg
    55561 tgattacagc aactggcaca caagcctaca gtagccaata ttacattgta aaactcacta
    55621 agaaaacaga aaaatcatct aatattgatg actacaaaga aaaattaaaa actgttatct
    55681 tgactcaaaa acaaaatgat tcaacatttg ttcaaagcat tatcggaaaa gaattgcaag
    55741 cagccaatat caaggttaag gaccaagcct tccaaaatat ctttacccaa tatatcggtg
    55801 gtggagattc aagctcaagc agtagtacat caaacgaata gtccaaatca atgagtcagg
    55861 gaaaaaactc gacttcagga aaaaatgaag caaacattcc cacaataaaa cgcatagtac
    55921 aaggtttgta ctgcccccca aaaaagttag acaattaatt tatccgaagg atttagttct
    55981 gtattgcaca gagctaagtc cttttagttt tatcttaatt ctcttattgt tgtaataatc
    56041 aatatagtct ataatggctt gttccaattg attaagtgat ttaaatgttt gctcatagcc
    56101 ataaaacatt tcggatttta aaatgccaaa gaaagattcc atcctaccgt tgtcttggct
    56161 gtttcctttg cgtgacatag atgcttgaat tcccttactc tctaggaagc gatgataaga
    56221 atcgtgttgg tattgccagc cttggtcact atggagaatc gtattctcgt agtgcttctc
    56281 tttgaatgcc tgttccaaca ttaacgatca atcaatttaa tcatgtacct aagattagaa
    56341 ttgtttatcc caaatttatt tgaaagcttc tctaagctat atccttgttt tctaagttca
    56401 tagatctgaa ctttatcatc ataagttaat ttcataataa aaacacccca aaagttagat
    56461 tttttctgtc taacttttgg ggtgtagttc atgtacacct gatatgatgc gttttataat
    56521 tttaaagact ttttgaccag cctcattttt ttaacttgat actcagtgaa aagcaaagat
    56581 taaactagga agctagctgt aggctgctca aagaacagct ttgaggttgc agataaaact
    56641 tgtgaggtaa ccaacatata taatgtgaag ctgacgtggt ttgaatagat tttagaaggg
    56701 tatgagtctg gaagttttaa tggataatgc aagattccat agaatgggta agctagagtt
    56761 cttatgtgaa gagtttgggc ataaactttt accttttcct ccctactcat cttagtatag
    56821 aaaagtgaat ctaaaatagt acataactgc ttctaaaaca ttcttataaa ttgatttaaa
    56881 ttctcaaatc atattattca gttcttattt cattttgctc tacaatcctg ttgagaagac
    56941 acgtgttcat atcaaaaagg tattggcaag ttgcaatacc tttttacaag gttcttttgt
    57001 cttatttttg tttcaactga ctatatctcc tatggttcta gttcagaagg ctaggctata
    57061 attatgattg ataagaagta tcattccaag tattgagagt gaatgtttca aaatcatggg
    57121 tttctataat ggtcaggctg gcatttgcta gaccgccatc tttacgaaga agtggttctt
    57181 tatagcctag gagagtacga agactggcag taagattggc gccgtgtccg acaattagaa
    57241 tacgctcagc tggactatct tttaatgatt tgataaattg gatggtccgc tgagttgtac
    57301 tatagaggga ttcggctccg aacattcgag tgtcaaattg agcaagattt gaacgaaaag
    57361 cctggatttg ttgcgggtaa atagcttcca gggttgcaat tttcaaacct tctaacttcc
    57421 caagttgcca ttcacggaga ttaggaacga tttctaaaga acagggggta tggagttgac
    57481 tttggataat ctcagcagat ttgaccgctc gaggtaaatc acttgaataa atctgatcaa
    57541 aaggaatttc cttgagatac tggccaagtc gttttagggt ttcaatggat tcaggaagaa
    57601 gaggagaatc accgctagca ccttgaaaac gaccttcttg gttccagagg gtacgaccgt
    57661 ggcggacaaa gtagagtttc attacttgat gtcctccaaa atatctacaa agtctgcctt
    57721 tacaaagcta gccaagtctt gtggcgcgac gataatgctg tgtccgactt cgcctgcaga
    57781 gacaatcatt cgatccaaat ctagagcaat tttatcgata aaaatgggat aattgtgttt
    57841 ctgacgaatt ccgacaggat tattggctcc atgaatgtaa ccagttgttt tttctaagtc
    57901 cttttgtaga atcatgctca cttttttatt gccagaaatt ttagctagtt tcttttcaga
    57961 caagtgctga gtgataggga caattccgat aatcggtccg gtcttgtctc ccaaaagcgc
    58021 caaggttttg aaaatctgat ctcgttcata accttgagga agctctcctt ctagggcatt
    58081 gatttgaatc ccctgatgag ggatggctgc tttagatagg atttgttcca ccaatgtttt
    58141 tttgatttta actttttttg ccattattta tatttatcct ccaattgact catccaaata
    58201 ccaagccaga ttcccagcgc aaagaagaag gcgatgatga cataaccgac aagtgaaagt
    58261 cctgtgtatt ggatactttc agcgtttcct gcatttggaa ttaagatcaa aagggtactt
    58321 gataggacga taccgatgat gaaatgatag acgcgtgagt ggtagttgtt taaggcataa
    58381 tccatcaatt ttgaaaaaac gatgagagtt gcacctgcac caattccaat cggaaagaag
    58441 gttcccaaga gatcaaaagt tttaaaacca gtcaacatag gagcatagag tcccaaaatc
    58501 aaaagtaaat tcgatgggct gaggccagga accaagacgc caagggccaa tagtgcgcct
    58561 gctaggacga agttaagaaa gctggcgctt aaggttccaa cgacaaaatt taaggcatat
    58621 agtcctaatc cagaaatgat aaaggttgtc cataaccaag ctaaatcaat cttgtctcgg
    58681 tcagattctc gagttgattc tttgaggagg ctaggaactg taccgataat agctcccgca
    58741 aagctccata atacaaagac ctgataattt tcaagcaggt attcaatcgg gtaggaaaat
    58801 aagccgattc ccagaagcat accgatggca actggaataa agtacaaaac attttcttta
    58861 aggtctttaa agggatgggc cagaaagcca atcattcgtt catagattcc taagattgct
    58921 gctagaaccc ctccggaaat tcccggtagg ataaatccaa gagcaattac aatcccttta
    58981 ataacgcgtg ctaaccatga gagcatatat ttcctccaac tatttctatt tcaaaaaatc
    59041 cttactatat tgtatcacaa tcagacacaa aaagaaaaag caaatgataa acaaatgctt
    59101 ttaaggtttt aaaaaaagct ttcgaaaggt ttcttcttta ttttttaagg gagagataac
    59161 gttgatatct aaatcgtggt caaagccggc aatttttcct ttagatgtgt attggtgaat
    59221 atcataatct aaatcagttt taggactgct ctccaaaaat cctgagtctg agccgtagga
    59281 cggaatccaa acagaggtaa acttgcctgt atcaatactg tgttcttcca tgaagtagac
    59341 accaacgtag atgccgatgt ttttagcacc tagtgatgct agttttgctc gaaagttttc
    59401 gacaccttcg ttcatattag acatagtttt gtcttccacg tcaagccaat agtaactagg
    59461 gctgtaagga gaggcagcat tgtagaaaac ttcggcagcc ttttccattt cttggacact
    59521 ttttccagct acataagcgt agacagcaac tgggacattc cgcttttgaa gttcagtgat
    59581 atgactctta taggccttgt ctattccatt gataaatgaa gcatcatttt cttttgtcgt
    59641 ttgagcacca ctgtgaacac gaacaatagc acctgaaata ttttgtgaga gggcatcgta
    59701 gttgatttcc tcaggacgct gccagccaga gaggtcaata atcggtttgt ctaagtgttt
    59761 caaagcctgt gcttcaatct gtgctatatt ggattttgtt ttaaacgatt ggctgtcatt
    59821 aagtgggcga ttgatgatta aaatgaacat cataatccca aaaaaactaa ataaaataag
    59881 tggatgaatt tgttttctca tatcttataa ttctacccta aaaatcaaaa aaaatcaaaa
    59941 aaatgggtta aggaagagac tttagagcat tttttcattc aagagtgcgg aatgatttga
    60001 aatatggtat aataaaaggg aatttctaca gaaaagagaa gattatgtca aattttgcca
    60061 ttattttagc agcgggtaaa gggactcgca tgaaatctga tttgccaaaa gttttgcaca
    60121 aggttgcggg tatttctatg ttggaacatg ttttccgtag tgtgggagct atccaacctg
    60181 aaaagacagt aacagttgta ggacacaagg cagaattggt tgaggaggtc ttggctggac
    60241 agacagaatt tgtgactcaa tctgaacagt tgggaactgg tcatgcagtt atgatgacag
    60301 agcctatctt agaaggtttg tcaggacaca ccttggtcat tgcaggagat actcctttaa
    60361 tcactggtga aagcttgaaa aacttgattg atttccatat caatcataaa aatgtggcca
    60421 ctatcttgac tgctgaaacg gataatcctt ttggctatgg acgaattgtt cgtaatgaca
    60481 atgctgaggt tcttcgtatt gttgagcaga aggatgctac agattttgaa aagcaaatca
    60541 aggaaatcaa cactggaaca tacgtctttg acaacgagcg tttgtttgag gctttgaaaa
    60601 atatcaatac caataacgct caaggcgaat actatattac agacgtcatt ggtattttcc
    60661 gtgaaactgg tgaaaaagtt ggcgcttata ctttgaaaga ttttgatgaa agtcttgggg
    60721 taaatgaccg tgtggcgctt gcgacagctg agtcagttat gcgtcgtcgc atcaatcata
    60781 aacacatggt caacggtgtt agctttgtca atccagaagc aacttatatc gatattgatg
    60841 ttgagattgc ttcggaagtt caaatcgaag ccaatgttac cttgaaaggg caaacgaaaa
    60901 ttggtgctga gactgttttg acaaacggta cttatgtagt ggacagcact atcggagcag
    60961 gagcggtcat taccaattct atgattgagg aaagtagtgt tgcagacggt gtgacagtcg
    61021 gtccttatgc tcacattcgt ccaaattcaa gtctgggtgc ccaagttcat attggtaact
    61081 ttgttgaggt gaaaggatct tcaatcggtg agaataccaa ggctggtcat ttgacttata
    61141 tcggaagctg tgaagtggga agcaacgtta atttcggtgc tggaactatt acagtcaact
    61201 atgacggcaa aaacaaatac aagacagtca ttggagacaa tgtctttgtt ggttcaaatt
    61261 caaccattat tgcaccagta gaacttggtg acaattccct cgttggtgct ggttcaacta
    61321 ttactaaaga cgtgccagca gatgctattg ctattggtcg cggtcgtcag atcaataaag
    61381 acgaatatgc aacacgtctt cctcatcatc ctaagaacca gtaggagcct atcatggagt
    61441 ttgaagaaaa aacgcttagc cgaaaagaaa tctatcaagg accaatattt aaactggtcc
    61501 aagatcaggt tgaattacca gaaggcaagg gaactgccca acgggatttg attttccaca
    61561 atggggctgt ctgtgtttta gcagtaacgg atgaacaaaa acttatcttg gtcaagcagt
    61621 accgcaaagc tatcgaggct gtctcttacg aaattccagc cggaaaattg gaagtaggag
    61681 aaaacacagc ccctgtggca gctgcccttc gtgaattaga ggaagaaaca gcctatacag
    61741 ggaaattaga actcttgtac gatttttatt cagctattgg cttttgtaat gagaagttaa
    61801 aactatattt agcaagcgat ttgacaaaag tggaaaatcc gcgtccgcag gatgaggatg
    61861 aaaccttgga agtccttgaa gtgagcttag aagaagcgaa agaattaatc caatcaggtc
    61921 atatctgtga tgccaagaca attatggctg ttcagtattg ggagttgcag aaaaaataga
    61981 ggaggtcagt atgggtaaat ctttattaac ggatgaaatg attgaaagag ctaatagagg
    62041 cgaaaaaatt tcaggtcctc ctttgctaga tgataatgag gaaactaaga ttttaccaac
    62101 ctcttcttcc cgttttggtt atgccaatcc taaggatcat ggttttagcc aggaaacctt
    62161 gaagattcag gtcgaaccat ctattcataa aagccgtcgc attgaaaata ccaagagaaa
    62221 tgtcttcaat tctaagttga ataaaatctt attcgcggtc atctttctct tgattttgct
    62281 tgttttagca atgaaacttt tgtaatagaa aaggaattga aatgaaaata ggaattattg
    62341 ctgctatgcc agaagaactg gcttatctgg tccagcattt agataatgcc caggagcaag
    62401 ttgttttggg gaatacctat catacaggaa ccattgcttc tcatgaagtc gttcttgtag
    62461 aaagtggaat tggtaaggtc atgtctgcta tgagtgtggc gattttggct gatcatttcc
    62521 aggtggatgc ccttattaat acgggttcag ctggggcagt agcagaaggt atcgctgttg
    62581 gagatgtcgt gattgctgac aaattagcct atcatgacgt ggatgtcaca gcttttggct
    62641 atgcttatgg acaaatggcg caacaaccgc tttatttcga atcagacaaa acctttgttg
    62701 ctcaaatcca agagagttta tctcaattgg accaaaactg gcatcttggt ttgattgcta
    62761 caggagatag ttttgttgca ggaaatgaca agatagaagc gattaagtcc catttcccag
    62821 aagttttagc cgtggagatg gagggggcag ctattgctca agcagcgcat gccctcaatc
    62881 tcccagtctt agtcatccga gctatgagtg acaatgccaa ccatgaagca aacatctttt
    62941 ttgatgagtt tattatcgaa gctggacgtc gctctgccca agtcttgttg acctttttga
    63001 aggctttaga ttaagcggaa atttgacagt ttttctagct tatgataaga tttaagtaaa
    63061 gaaaagctag aaaacgtttc agaggatatt atgagtattg aaatgaccgt cagtgagatt
    63121 gcagaggtct taggattatc tcgccaagca atcaataacc gtgtcaaaga attaccagaa
    63181 gaagacacag ataaaaatga caaaggggta acagttgtta ccagaagtgg cttgattaag
    63241 ctagaagaaa tctataaaaa aacgattttt gaagatgagc ctgtcagtga agatgtcaaa
    63301 caacgtgaac tgatggagat tctagtggat gagaagaatg cagaaattct tcgtctttat
    63361 gaacaattaa aagccaagga tcgtcagtta tcagaaaaag acgagcagat gcgtatcaaa
    63421 gaccgtcaga ttgctgaaaa agacaaacaa ttagatcagc aacaacaatt gacccttcaa
    63481 gccatgaagg atcaagaaaa tcttaagcta gagctggacc aagcaaaaga agaagtccaa
    63541 tccactaaaa aaggcttttt tgctcgttta tttggaggat aatcaaggag ctgtttaggt
    63601 taaatgctaa cctgatggct tcttttgttt gtgaatagta tagttgatta gaacagagac
    63661 agtagaggag aggtacagaa tggaacgatt agaagattac attgcttttg acttagaatt
    63721 taatcagcac gaaggacaaa cacacttgat tcaagtatcg gcagtgcgtt ttagagatgg
    63781 tcgggaaatc gatgcctatg attcctatgt tcataccagc gtccctctaa aaagctttat
    63841 caatggtttg accgggatta cagctgagac cttaaaagat gctcctccag ttgagaaagt
    63901 cttagaagaa ttccaagagt ttgtgggttc tttgctgatg ataggctaca atgctgctaa
    63961 aagtgattta cctattttag cagagcatgg tttagactat agccaacagt acaaggtgga
    64021 tttgtatgat gaagcttttg aacgtcggag ttcagattta catggtattg ccaatctcaa
    64081 attgcaaact gttgcctcat ttcttggatt tcaaggtcag tctcataata gtttagagga
    64141 tgctcggatg acggcgcgtg tttacgaatc cttcttagag tcggatcaag ctagggaatt
    64201 gttagagaca gaaagtagct tatcaaacaa tccttttggt ggcttggact tgtctcaatt
    64261 atttgactag gagtgcctat gaaacctgaa aaacctaaaa aattgggtct taaacagatt
    64321 tacctcaatc ttgataaaat cctctttcta tttttcttga tttttatgat agtggagtat
    64381 ttgtgggtac cattcaattc atggttggct agcttcttat tagatcagac aggttatctt
    64441 tttatttcct ataacaatgt cttagccatc cttactcatt ctccattgat tagtctagct
    64501 tttttagcct tgattgtaat taaccttctg gttgcttatt ttcaaatagg actcctcttt
    64561 attggtgctc gtcatctcct ctataatgaa aagcgaaggc taattgagta tatccgcaag
    64621 gttttccatg aaagttttgg atttatgaaa aagctaactg gcgctaaagc cttgtttatc
    64681 tttttctata tagctatgct ttttcctttt atacggaaaa tgctgaagat ttattatctt
    64741 aataaaatcg tcattccaga gtttatccaa gcttatttag aagataaata ttggatgtgg
    64801 tggctgagca tcctacttct atctcttatc tttctctatg tctctgtcag attgatgttt
    64861 gcccttccga agattgtata tgatcagctg actgttcgag aagcagtgat gtttagcttg
    64921 gagaaaacca agaagagagt tactttttat gcttggaatt tattttacat cttgctcaaa
    64981 gcacatttat tattttatct tcctttgatt cctttattat tggctcaaac tttggtagat
    65041 gatatcactc agagagagtc tctgattctt ggtattttga attttgtcgt gattaaaaat
    65101 ctctattata tggctctgac ttattttttg gttaaatttg tttcattttt gacaggaaag
    65161 gagctggata tgcttcctag gagagaaaaa gatcacatcg tgcgatgggg tgtcatgact
    65221 tgtgccagtc ttttctttgc cttagaaggt tatatttatc tggaggctcc catggttcat
    65281 ctacctcaac ttatttctca ccgaggggtt tccaatgcaa atgggattca aaatacagta
    65341 gagtccttgg aaactacagc acaactcaaa ccagacttgg tggagacgga cgtgcaggaa
    65401 acaaaagatg ggcagtttgt catgatgcat gatgctaact tgaaaaatct agcaggtatc
    65461 aataaaagtc ctcaagactt aaacttggag gagcttaaag ggattgatat ttttgaaaat
    65521 ggctaccaga ctaaaatttc aagctttgaa gattatctca gtcgagccaa cgaacttggt
    65581 caaaaattac taattgaaat taaaaccagt aaaaaagata gtccagacat gatggaccgc
    65641 tttttagccc gttatgctgc aaagctcaag atttatggac atcaaatcca gtctttagac
    65701 taccatgttg tcgaaaaagt aagacagtat gatgccgaac tgccagttta tttcatcatg
    65761 ccctacaatt ctgtctttcc taaaacaaga gcgacaggat atactatgga gtactcaacc
    65821 ttggatgaat attttgtaag caaactatgg acaacggatc agaaacttta tgtctggact
    65881 gtcaatgatt cagaagctat cagcaaatct cttcacttag gagtagatgg agtgattaca
    65941 gatgatttgg aaaaagttca gcgggaaata gaagtagccc aagaagatcc agaatatacg
    66001 gatttgctct tgaaaaaagc attggaattc tttgaatttt agtaataaaa aagaggaacg
    66061 gttgttcctc ccatgatagg taagtattct tgtgaatgct tgcttttttg tggttgcaat
    66121 ccgtttacga gaattgtttg tattgttctt gtttcaattt actttatagt gctttgaagt
    66181 tggaatacta cactataact tctaaaatat agtaaaatga accaaaaata gtacacaatg
    66241 tggtataatc tttttatggc atattcaata gattttcgta aaaaagttct ctcttattgt
    66301 gagcgaacag gtagtataac agaagc
//
LOCUS       DAVKMO010000006        59852 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVKMO010000006 DAVKMO010000000
VERSION     DAVKMO010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59852
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.006"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..261)
                     /locus_tag="VW361_000427"
     CDS             complement(<1..261)
                     /locus_tag="VW361_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9743550.1"
                     /translation="MQDNYTTKGKHLTIDSRSLIERWKKEGKSNREIASLLGKAPQTI
                     HTKIKRRTVRKCLGKGRFKEVYSADYAQQSYENNRKHSVKRSS"
     gene            complement(706..1104)
                     /locus_tag="VW361_000428"
     CDS             complement(706..1104)
                     /locus_tag="VW361_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9743551.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            complement(1432..1914)
                     /gene="greA"
                     /locus_tag="VW361_000429"
     CDS             complement(1432..1914)
                     /gene="greA"
                     /locus_tag="VW361_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU9743552.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(1985..3640)
                     /gene="mltG"
                     /locus_tag="VW361_000430"
     CDS             complement(1985..3640)
                     /gene="mltG"
                     /locus_tag="VW361_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU9743553.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     IRDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLIKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(3721..4215)
                     /locus_tag="VW361_000431"
     CDS             complement(3721..4215)
                     /locus_tag="VW361_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9743554.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(4212..4676)
                     /locus_tag="VW361_000432"
     CDS             complement(4212..4676)
                     /locus_tag="VW361_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9743555.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEETLLYVTSQGYSMIWFNPFYLEEQ"
     gene            complement(4686..6020)
                     /locus_tag="VW361_000433"
     CDS             complement(4686..6020)
                     /locus_tag="VW361_000433"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU9743556.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(6031..6648)
                     /locus_tag="VW361_000434"
     CDS             complement(6031..6648)
                     /locus_tag="VW361_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9743557.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(6696..9800)
                     /locus_tag="VW361_000435"
     CDS             complement(6696..9800)
                     /locus_tag="VW361_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9743558.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINRQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADTNLFAFTVTEYLDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKVLPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDVDLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQKLGQFELKDGTLQARKSLAYSLAHLFEGRDRDRVSFSQEFQNLAQ
                     DLTHPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFL
                     TSQVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILADSHQIYVT
                     SYATFRQDSELYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENH
                     LGELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVY
                     KNELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMED
                     YQGASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPA
                     KERQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHR
                     MGQEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGIS
                     EAST"
     gene            complement(9893..11059)
                     /locus_tag="VW361_000436"
     CDS             complement(9893..11059)
                     /locus_tag="VW361_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9743559.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IHQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHSRINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(11067..12161)
                     /locus_tag="VW361_000437"
     CDS             complement(11067..12161)
                     /locus_tag="VW361_000437"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9743560.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(12319..14001)
                     /locus_tag="VW361_000438"
     CDS             complement(12319..14001)
                     /locus_tag="VW361_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743561.1"
                     /translation="MKLKLLRVDTKVIMGSFFLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILPLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTIYSSSKGSSVALENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENR
                     PVLKDITCSIFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKE
                     WRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDT
                     EVGERGRLLSGGRSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYSVLKEK
                     TVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            complement(14173..16131)
                     /locus_tag="VW361_000439"
     CDS             complement(14173..16131)
                     /locus_tag="VW361_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9743562.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(16335..17957)
                     /locus_tag="VW361_000440"
     CDS             complement(16335..17957)
                     /locus_tag="VW361_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9743563.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTTKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            18063..19508
                     /locus_tag="VW361_000441"
     CDS             18063..19508
                     /locus_tag="VW361_000441"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU9743564.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLCLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(19554..19748)
                     /locus_tag="VW361_000442"
     CDS             complement(19554..19748)
                     /locus_tag="VW361_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9743565.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(19849..20457)
                     /locus_tag="VW361_000443"
     CDS             complement(19849..20457)
                     /locus_tag="VW361_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU9743566.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDHL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            complement(20482..20994)
                     /locus_tag="VW361_000444"
     CDS             complement(20482..20994)
                     /locus_tag="VW361_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU9743567.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            complement(21080..22015)
                     /locus_tag="VW361_000445"
     CDS             complement(21080..22015)
                     /locus_tag="VW361_000445"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU9743568.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(22086..22385)
                     /locus_tag="VW361_000446"
     CDS             complement(22086..22385)
                     /locus_tag="VW361_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU9743569.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(22375..23124)
                     /locus_tag="VW361_000447"
     CDS             complement(22375..23124)
                     /locus_tag="VW361_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU9743570.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(23178..23537)
                     /locus_tag="VW361_000448"
     CDS             complement(23178..23537)
                     /locus_tag="VW361_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU9743571.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELEMGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKTK"
     gene            complement(23539..24939)
                     /locus_tag="VW361_000449"
     CDS             complement(23539..24939)
                     /locus_tag="VW361_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU9743572.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(25234..25473)
                     /locus_tag="VW361_000450"
     CDS             complement(25234..25473)
                     /locus_tag="VW361_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU9743573.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(25505..25975)
                     /gene="ssbA"
                     /locus_tag="VW361_000451"
     CDS             complement(25505..25975)
                     /gene="ssbA"
                     /locus_tag="VW361_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU9743574.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(25987..26277)
                     /locus_tag="VW361_000452"
     CDS             complement(25987..26277)
                     /locus_tag="VW361_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU9743575.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(26430..27776)
                     /gene="asnS"
                     /locus_tag="VW361_000453"
     CDS             complement(26430..27776)
                     /gene="asnS"
                     /locus_tag="VW361_000453"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU9743576.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGMPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(27792..28157)
                     /locus_tag="VW361_000454"
     CDS             complement(27792..28157)
                     /locus_tag="VW361_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9743577.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKMAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEGVQPCYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(28150..29337)
                     /locus_tag="VW361_000455"
     CDS             complement(28150..29337)
                     /locus_tag="VW361_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9743578.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(29334..29822)
                     /locus_tag="VW361_000456"
     CDS             complement(29334..29822)
                     /locus_tag="VW361_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU9743579.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            30143..30691
                     /locus_tag="VW361_000457"
     CDS             30143..30691
                     /locus_tag="VW361_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9743580.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(30969..31697)
                     /gene="yaaA"
                     /locus_tag="VW361_000458"
     CDS             complement(30969..31697)
                     /gene="yaaA"
                     /locus_tag="VW361_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU9743581.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKALKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(31776..31940)
                     /locus_tag="VW361_000459"
     CDS             complement(31776..31940)
                     /locus_tag="VW361_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU9743582.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(32119..33714)
                     /locus_tag="VW361_000460"
     CDS             complement(32119..33714)
                     /locus_tag="VW361_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743583.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFSKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            complement(33726..34136)
                     /locus_tag="VW361_000461"
     CDS             complement(33726..34136)
                     /locus_tag="VW361_000461"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9743584.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRV
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(34252..35043)
                     /gene="yghU"
                     /locus_tag="VW361_000462"
     CDS             complement(34252..35043)
                     /gene="yghU"
                     /locus_tag="VW361_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU9743585.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(35056..37752)
                     /locus_tag="VW361_000463"
     CDS             complement(35056..37752)
                     /locus_tag="VW361_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU9743586.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38056..39240
                     /gene="mntE"
                     /locus_tag="VW361_000464"
     CDS             38056..39240
                     /gene="mntE"
                     /locus_tag="VW361_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU9743587.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(39383..41254)
                     /locus_tag="VW361_000465"
     CDS             complement(39383..41254)
                     /locus_tag="VW361_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9743588.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDNQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQDVSFAYENKPILQN
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(41251..42435)
                     /locus_tag="VW361_000466"
     CDS             complement(41251..42435)
                     /locus_tag="VW361_000466"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU9743589.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALESETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(42447..43214)
                     /locus_tag="VW361_000467"
     CDS             complement(42447..43214)
                     /locus_tag="VW361_000467"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU9743590.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTAPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(43491..44339)
                     /locus_tag="VW361_000468"
     CDS             complement(43491..44339)
                     /locus_tag="VW361_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9743591.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGMIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGSGSIAL
                     GYIPVI"
     gene            complement(44341..44715)
                     /locus_tag="VW361_000469"
     CDS             complement(44341..44715)
                     /locus_tag="VW361_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU9743592.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(44789..46141)
                     /locus_tag="VW361_000470"
     CDS             complement(44789..46141)
                     /locus_tag="VW361_000470"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU9743593.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEALKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(46165..46944)
                     /locus_tag="VW361_000471"
     CDS             complement(46165..46944)
                     /locus_tag="VW361_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU9743594.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(46931..47788)
                     /locus_tag="VW361_000472"
     CDS             complement(46931..47788)
                     /locus_tag="VW361_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU9743595.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERW
                     LGGWKHEKK"
     gene            47924..48892
                     /locus_tag="VW361_000473"
     CDS             47924..48892
                     /locus_tag="VW361_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9743596.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPGQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(48926..49837)
                     /gene="whiA"
                     /locus_tag="VW361_000474"
     CDS             complement(48926..49837)
                     /gene="whiA"
                     /locus_tag="VW361_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU9743597.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(49834..50811)
                     /locus_tag="VW361_000475"
     CDS             complement(49834..50811)
                     /locus_tag="VW361_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU9743598.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGIEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(50808..51698)
                     /gene="rapZ"
                     /locus_tag="VW361_000476"
     CDS             complement(50808..51698)
                     /gene="rapZ"
                     /locus_tag="VW361_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU9743599.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLLELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLVQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(51750..52130)
                     /locus_tag="VW361_000477"
     CDS             complement(51750..52130)
                     /locus_tag="VW361_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU9743600.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(52141..52728)
                     /locus_tag="VW361_000478"
     CDS             complement(52141..52728)
                     /locus_tag="VW361_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU9743601.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(52737..53969)
                     /gene="clpX"
                     /locus_tag="VW361_000479"
     CDS             complement(52737..53969)
                     /gene="clpX"
                     /locus_tag="VW361_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU9743602.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(54001..54171)
                     /locus_tag="VW361_000480"
     CDS             complement(54001..54171)
                     /locus_tag="VW361_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743603.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(54171..54677)
                     /locus_tag="VW361_000481"
     CDS             complement(54171..54677)
                     /locus_tag="VW361_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU9743604.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEAYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(54807..55325)
                     /locus_tag="VW361_000482"
     CDS             complement(54807..55325)
                     /locus_tag="VW361_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU9743605.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            complement(55821..57143)
                     /locus_tag="VW361_000483"
                     /pseudo
     CDS             complement(55821..57143)
                     /locus_tag="VW361_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-beta-N-acetylmuramidase"
     gene            complement(57181..57939)
                     /locus_tag="VW361_000484"
     CDS             complement(57181..57939)
                     /locus_tag="VW361_000484"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU9743606.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNFKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            complement(58036..58713)
                     /locus_tag="VW361_000485"
     CDS             complement(58036..58713)
                     /locus_tag="VW361_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU9743607.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            complement(58722..59666)
                     /locus_tag="VW361_000486"
     CDS             complement(58722..59666)
                     /locus_tag="VW361_000486"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU9743608.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWIKIEDDASAYGYL"
BASE COUNT        17228 a        13626 c        11224 g        17774 t
ORIGIN      
        1 gcttgatctc ttgaccgagt gcttgcgatt attttcataa gactgttgag catagtcggc
       61 agaataaacc tctttgaagc gcccttttcc aagacatttt cggactgtcc tacgcttgat
      121 tttagtgtgg atagtttgag gagcttttcc aagtagagag gcaatttctc tatttgattt
      181 tccttctttt ttccatcttt cgattaagct acggctatcg attgtcaaat gtttaccttt
      241 tgtagtataa ttgtcttgca tttctgtgcc tttcttgtgt ttgtggttga acaacaagta
      301 taacacagag gtgttttctt atgcctacaa gagctttcat tatttccatt ttcttttgga
      361 tttcactcta ttctgaaaaa cttgtgtata tttactgaag ctagcaagtc ttacctgtaa
      421 atttaatgaa agcaacacaa aatccgagag gggaatctcg gattaataga tagagagttt
      481 ttagtttaaa taaattgttt aaaatatcaa caacatcact tcttttctta acctgataag
      541 tcttgattcc taattttggg gctacgatta tattgtcctc aatatcgtct agaaagacac
      601 aatttctagg ttataactgg tatttatcga tagttactca tatacatcag tccacctcca
      661 tacttatgtg cgagcctctc tttgtattat acctccatac tcaccttaca gattcttttg
      721 gtaataatat ctttgcctaa tgtagagata gtcttgcaaa gaaaaaactt ccttgtagcc
      781 atgtttctga taaaagtccg gtgcctggaa ctggtaagta ttgacaaagg caaaacaaca
      841 atttcgattc ttagcttcac tttctgcctg ttgcaatagt tttgaaccga ttccttgtcc
      901 tcgcagttcc tcttttacaa acaaatactc gatttctagc caatttccaa aagtctctgc
      961 tatcaaacct gccaggagat tgcccttttc atcttcgaca taaagattaa gtggctcact
     1021 ttcagcctct tctctttttg aacggttata aacacgaatc agattcccta tttcttgcga
     1081 tttatgtgat tccttatttt ccaatctaaa gtatagtgaa atgaaataaa acatgcgcaa
     1141 atcgattaag gaatttaatc taatttctaa caatgtctta gaaatcaaag tgtactattt
     1201 taacttcaat gcactataca tctaatactc aataaaaatc aaagagcaaa ctaggaaact
     1261 agccgcaggt tgctcaaaac actgttttga ggttgtagat gaaactgacg aagtcagtaa
     1321 ccatacatac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag agtagcaaaa
     1381 tggaaaaagg agtgagtgaa gcacatcgcc tccccactcc tttttctgtt tttaggctgt
     1441 tttttcaacc ttcaagattt ttacatcata gctaccaaca ggcgtttcaa tggttgctgt
     1501 atcacctgtt ttcttgccaa tcaaggcctg cccaattggg ctttcatttg aaaccttacc
     1561 tgcaaaggca tccgcaccag ctgaacctac gataatataa acttcttctt cgtcctcacc
     1621 aatttcttgg atggtgactg ttttaccaat cgctacttcg tcctgggcaa ctgcgtcgct
     1681 attgacgatt tcagcatagc ggatttttgt ttctaagcta gagatttgtc cttcgacaaa
     1741 ggcttgttca tccttagctg cttcgtactc actgttttct gaaaggtcac cgtatgaacg
     1801 ggcaatctta atgcgttcta ccacttctgg tcgacgaacc aatttcaatt cttctaattc
     1861 tttttcaagt ttttcctttt cctcaagggt cataggatat gttttttctg ccatttttct
     1921 caactttctt ctgataatat tttctaaaga aaattatgtg aagtatcaca taattttagt
     1981 ttgtttagtt taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg tcttcttgat
     2041 tgttagcata gtagaccttg ccttctgtga catctgctac aaagtagagg ttatcgctct
     2101 tagtttgatt gatgcttgac tcaatcgcat ccagacttgg actatcgact ggaccaggca
     2161 tgagacctac atttttataa acattataag gtgaatcaat gttggtatca atcgcaacat
     2221 cctcagctag actgatattt tgccccagtt ttccttgggc atacaagatt gcaatattac
     2281 tttgaagtgg catatcacga ttcaaacgat tgtagaatac acctgcaatg agcttacgat
     2341 cttctgtctt ggcaccttct ttttcgacca aggaagcaat ggtcaacaac tcattgacag
     2401 tcaagttttt agatttgata gtactatagt aaggagatag gttcttatcc atagcagcta
     2461 acatctcatc aatcaagctc tcaatagttg tgctttcctt gatagagtat gtagctggga
     2521 aaaggtatcc ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa ctttccagta
     2581 aagtaggata tttcgctact gcttgactga taaacgtctc atcttgaact ttagccaaga
     2641 aagcctccgc tgtcaaagac tctttgaagt caccttgcaa ttgacccaca gtttgagcaa
     2701 tctgatccaa ggtataacct tctggaattg tcaaagtcgc aagtacaggt tcttgcggtt
     2761 catctgttcc acctttttgc aactctttga gtaagtcttc tgtactcata ctcttttgca
     2821 aattgtagta acctgctttc aagtcggtat aatttttata cttggcataa aaactaaaaa
     2881 tcagaccatg ctttatcaaa ccagcttttt caagcgtcgt accgatttct tgaacgtttg
     2941 aaccttctgg aattccaacc gtcacatatt tcttagaatt agcatcgata ggtaataagg
     3001 aatctagcac gtactggtaa ccaaagtaac cacctgctga gagcaaggca aggaatacaa
     3061 ggaatgaaat cacaaaagct ttcacatgtg acttcttctc tttcttaggc ttaacgggtt
     3121 ttgctccttc tctacggcta cgacgtgatg tatctctgat gatatccact gtttctgtag
     3181 caggcgtagg tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc gtataggaaa
     3241 cagctaccct tgttggggtt tcattgtatt ctctttcaag tttcttaggt ctaacaggac
     3301 ctggacctgg tcttgatcca ctttcttccg ctggagaaga aggtacatct tgacttggat
     3361 gacttggaac accaggagtt tctctttgaa tctcatctgc tggagaagct ggtacacctt
     3421 gacttgggtg agtaggcacg gtaggagctt ttctcataat ctcctctacc gttgacaagg
     3481 aatcagccat gagttcttca gctgaaggtt catttgcagg agtgcgaact actgcctcat
     3541 cttctttcag aacttcatca tagcctttta ctttttctaa atctctcaga atctgctctt
     3601 taaagcttaa tttctcttct tctcttgact tttcactcaa aagtttttcc tccttgttga
     3661 taatccataa tattatatct taaaagtcca aaaaaagcaa tctatgatac ttttcctaac
     3721 ttattttttc atttcccaga ccatatcata ccatgtttcc cctgcaaagg ttgactggga
     3781 ctggccttcg ttgacaaatc catgtttttc ataataggcg atgagatagt catgacaggt
     3841 tagattaatg ccatctctct catcttcaag agcaacttct ttcaaggctg tcagcaattt
     3901 ctgacccagt ccgagtccct gtgcctcctt ggcaatagac agacaggtca cagagatata
     3961 accaccaggc tcatgactat agtcttttat ttcttctgta aaagactggt cttgcagatg
     4021 gcggtgcagg ccaactggtc cttcgatata acccatgatt cttccttctt tttcagcaac
     4081 cagaaaagag gtctgaattt ctctcaaatg tgcttcaaag acagaaggag gaatggcttc
     4141 ttcgaccgaa aaattttcaa attcaagttc aacaatccga tccaaatctt ctaatcttgc
     4201 ttgtctgatt ttcattgttc ctccagataa aagggattaa accaaatcat actatagccc
     4261 tggctagtta catagagcaa agtttcttct tcatcaacaa aaccgttcat ttcaaaatag
     4321 gaaagcagct catcaggact ctccaaacga atccctttgt aatccagctc aactgccacc
     4381 tctttcaagg ctgcaagaag aagtgttccc aggccctgtc tctgatggtc agactcgatg
     4441 actaaagaat gtacttttag acattgcgga ttgtctgact ggggacttga taaaatatag
     4501 cctaaaagtt gattttcatc cctagctaga agaaaggtat ccgcacactt acggatactt
     4561 tcttctaaaa tatgggaaag ttgctgcttt tcagctggaa aagacgaggt ctgaagtgcc
     4621 cctatctcag gcaaatcaaa cttgcttgcc tgaatgatct taattggaat ttccatggga
     4681 acatcctatt gaacattgct tgtcaagtta gacaagagac gctcaaatga gtattcatag
     4741 gtttggatgt ctcctgctcc cataaagacg taaacagcat tgtcatggtc taggagtgga
     4801 gaaacatttt caacagtaat cacttggtgt tttttgttga ttttattggc taggtcttct
     4861 accttaacgt caccatgatc tacttcacga gccgagccat aaatttgcgc tagataaaca
     4921 gcatctgctt ggtttaaagc atgggcaaag tcgtccaaca gggcaatggt tcttgtaaag
     4981 gtatgcggtt gaaagactgc tacaatttcc ttgcttgggt atttctgacg agccgcatcc
     5041 aaggtcgcaa taatttctgt tggatgatgg gcaaagtcat caataatcac tgtatcattg
     5101 acaattttct cagtgaaacg acgtttaaca ccggcaaatg ttttcaagtg ctcacgcacc
     5161 aagttcaaat caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc attcatgata
     5221 ttgtgacgac caaaggttgg aatgtggaat tgccccaagt tttgtccacg gaaatgaacg
     5281 gtgaaggttg aaccagttgt tgaacgaaga agatcactag ctacaaagtc attgccttca
     5341 gcttcaaaac cataataata aattggtgca tcagacgtaa tcttacgcaa ttcagcatct
     5401 tcaccataga caaaaagacc cttggtaatt tgtttggcat agtcgttaaa ggcattgaaa
     5461 acatcctcga gacttgtgaa ataatctgga tggtcaaagt caatgttggt gataatagag
     5521 tattctgggt ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa gacaaaatat
     5581 ttggcattgg ccgaaccacg acctgtccca tctccaatca agaagctggt atctgtaatg
     5641 tgagacaaga catgagacaa catacctgtc gttgaagttt ttccatgtgc tcctgctact
     5701 cccatgctaa caaagtcacg cataaagcta cctagaaact catggtaacg tttgtagctg
     5761 ataccatttt ggtccgcata ggcaatttcg acgttgttat ctggacgaaa ggcatttcca
     5821 gcgataattt ccatatcacc gtctagattc ttttcatcaa aaggaagaat ggtaattcct
     5881 gcctgctcaa gaccgcgttg ggtaaagtag tacttttcaa catctgatcc ctgaaccttg
     5941 tgccccatct ggtgcaacat caaggccaag gcactcatcc ctgatccctt aattccgata
     6001 aaatgatatg tctttgacat gttttctccc ctattctgtc attctggtca gattcaactc
     6061 ttgggcaacc cgacgttctt gttctgtttg tttacttttt ttattgtaga tttggctctt
     6121 ctttagaaaa tcataattgt ttttctttgg agcaggtgct gacacttctt cattcttggt
     6181 agggatagaa tgaacttctt ccgccaagat ataatgagac tgggtcaatt tttggctata
     6241 tttgacaaat tcaccaggat tttccttttg gaaaggagtt gtcggttgat tgccctgtct
     6301 aactagactg ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta ggtagttagc
     6361 agagcgtttc tttttcaagt ccgcacgcgc ttcttcacgc gccacctccg catagctctt
     6421 tccttctttt ttaaccccta aaggagcctt tttaggtttt tcgacttgct tttcaatcgg
     6481 ttttactggt ttttcttcag caataggagc ccattctaaa taatttttat ctcgatactc
     6541 acccttgata ttactgatca gatcagactc atcatagaga ttcatgactg gcatttcagt
     6601 caacatgacc tcgtcatctg acaccaatgg aaatcgttct tgtttcattt tctatttcct
     6661 ttcaacactt cattatagcg tattgtcttg atttttcaag tgctggcttc agaaattccc
     6721 aaaatttctc taatttctgc tagggtcaga ctaccacgtg actctgtgcc gtccaatact
     6781 tgtgacacca gatgtttctt ttgttcttgg agttcctgaa ttttttcttc aatggttccc
     6841 ttggtcacca agcgatagac ctcaaccgtt tcttcctgac ccatccgatg ggcacggcca
     6901 atggcttgcg cttccaccgc aggattccac caaaggtcaa ccaagatcac tgtatctgca
     6961 cctgtcaggt tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc atctctttct
     7021 ccttggttaa aggccttggt catgtcttgt ctttccttgg ctggggttga acccgtaatt
     7081 ttaaaggaag tcaggcccaa gtctggcagt tcttgttcaa ttttttccaa cattcccttg
     7141 aactgagaga aaatcaagac acggtgtccg ccgtctgcca cctgtaccag taggtctcgg
     7201 agactatcta gtttgccgct ggctccctga taatcttcca taaacagggc aggagtgtca
     7261 catatttgac gcaagcgcat caaaccagat aaaatttcca cacgacttcg ctgaaattcc
     7321 tgttctgaca cttgagccag atggtctcgc atctgttgta actgggcaag gtaaatagcc
     7381 ttttgctggt cttccagttc atttttataa accacctcaa tcaagtctgg caattcagtc
     7441 agaacttctt ctttcttgcg tcgcatcacg aaaggcttga taaactgagc cactcgctct
     7501 gctggcaatt tcataaattc tttcttgctt ggcaaaagtc cgggcatgac gatttggaaa
     7561 atagaccaca actcacccag atggttttca atcggagttc ctgacaaggc aaagaccgac
     7621 ggcaccacaa attgtctcaa ggtctgggca atcttggtct gggcattttt catgacctga
     7681 gcttcatcta agaaaaggaa gtcaaaggcc atcccctgat aaagctcact gtcctgacgg
     7741 aaggtggcat agctagtcac atagatttga tggctatcgg caagaatctc ctcacgactt
     7801 gctttcaaac catgaacaac agccacatcc aactgtgggg caaatttctg aaactcatcc
     7861 gcccagttgt aaatcaaacc cgacggagcg agaatcaaga ctcgactttc ttttgtcact
     7921 tgactagtca aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc atcagccaaa
     7981 atcccaccaa aaccataatg atggagcatc tgcaaccagc caattccctt ttcctgataa
     8041 tctcgcaagt cagccttgac ctgagttgct tgcaaaggaa agtcctctgg atgcgtcaaa
     8101 tcctgggcca gattctggaa ttcttgtgaa aaagaaacac ggtctcggtc tcgcccttca
     8161 aagagatgag ctaaactgta ggccaaggat ttccgagcct gcaaggtccc atcttttaat
     8221 tcaaattgcc ccagtttctg taaattttgg cgaattttct tggtttcttc atcgaaaaag
     8281 taaacttgat tagacgaatc aatataaaaa tcctgattgg caaccaaggc ctgcatggct
     8341 tggtcgattt cctcctgggc aatatcttga aaatcaaact ggatttccaa gagacctccc
     8401 ttggaggcaa tctgcacctg aggactcgct aggctataaa gctcttctag tttatctgat
     8461 aggtcaacat gcccgagttt ttcaaagact ggaatgatat catgaaaaaa atgatagaca
     8521 gactctgctt ttaaggcctg acgccaagat tgaaaatcgg cttcaaagcc cgcagccaaa
     8581 cagacttgga aaattctttc ttctaagtcc acgtcacttg aaaatggtaa ttcttctagc
     8641 tcttgtcggc tagatacctg tctatttcca taatcaaact gaatttctaa acgaatccga
     8701 ttatcttctt ccctgtcaaa gtaaaaagag ggcgcaaaag ttttgatttg tagacgttct
     8761 ggagctgaaa cggtgcccat ctggataaaa agagtcagac aggaggccaa tttgtctcga
     8821 tcactgctat caaattgcag gtatttcttt ccttgttgac ccacaggtaa cactttaatt
     8881 tccttgagaa gacgcatctg ctggtctgtt aaaaaataaa cctgaccttt atggaaaagt
     8941 actgctccct gataaaagac attgacccta ggactctcac tgatttccat ttcaaaatag
     9001 tccaagtatt ctgttactgt aaaggcaaat agattggtat cagcatgcat atcctgaaaa
     9061 agcagggttt ggtagctatc cacttgatgg tcaaattgaa aatggggcaa ggccatcagt
     9121 aaattcacac cctgctcaaa aaaggtcaga gggaaaaaga ggtgccgacc ttggttttgg
     9181 aaaaagaggt ctggaaccag cccttcctcc gttagtccgt gcaagaaagt caaaagttct
     9241 tggctggcat catcaaaggc ttcccaagaa agagactcct cataaatctt gccaatcata
     9301 tacgactttc tctgctcgac aatccttaaa aaaagtggaa tatcccgaat gacatagtat
     9361 ttttgtctat tgatttggcc gattctcaga gtccacaaga tatgattggt tcctgcttcc
     9421 acctgaccca cagctgataa ctcataggcg cattctgatt tcggagataa aattcgattc
     9481 aaaaacttgc cacccaaggt caccttggtt tcaacggcct ctttttcttc atgaccttct
     9541 tccagactcc acaagatttc ctgaccacgc tcatcatttt tcagaaaatg ctctagcgct
     9601 gccaaatgca cacagtagcc cctcttttga aaagaatcac aggcacaaaa aaccaaatca
     9661 tcctctaaac tatagcgcag ttcttcttct gcaacgcgag cgtagagccg attgttcttt
     9721 tccttgatga tatcaacctt accagtttca taaagggcaa caccttcgat acgaactttc
     9781 cccggaatca atttagccat attttcacct ttaccttatc tgtttattat accatatttt
     9841 cgcctatgaa aatagccttc taggaagact tttctcctag aaggctggat ttttaacgtt
     9901 tggcaaaagt agccacaatc cgctgacaga cttcttgcaa cagagatttg ggcatagcta
     9961 tattgatgcg ggaatggaga cttccttcct ctccaaaatc caaaccacgg ttgaggataa
    10021 ccttggcttc atttctcaac aactcttgca atgtttcatc agtcaggtca taggctgaaa
    10081 agtcaagcca aatcaagtag gtaccttgcg gtttcatgac cttgatttta gtctcttttc
    10141 caaatagatc caccacataa ttgatgtggt cttcaaagac ttgcttgagt tcctctagcc
    10201 aatctttacc gtatctatag gcagcttctg tcgccaaata acccaagcct gaaatttcat
    10261 gctgattatt ggccaacagg cgtttctgga aagctagtct caacttagga ttttcaatga
    10321 ctgcatagga attttttgtt ccagcaatat taaatgtttt agtggcactg ctcaagacga
    10381 tagcaaaatt tttgaaggca ggattgatgg tattgaaaga ctggtgtttg tgaccaaaga
    10441 gggtcaaatc ttggtgaatc tcatccgaaa ctaacaaaac accgtgtttt tggcagagtt
    10501 ggccaatctt ctccaacact tctttttccc aaacacgtcc accaggattg tgagggttgc
    10561 aaagaatata gagtttaacc tcctcttcca ccaaatcctt ttcaagttgg tcaaagtcaa
    10621 tctcaaacag actatccttt tccactaagg aattagtaat caatctacga ttattcaact
    10681 tgacactgcg agcaaagggt gggtagacag gcgtgttaat taaaaccgcc tcgccttctt
    10741 ttgtaaaggt ttgaatagct gttgagatgg ctggtaccac accctcgata aagacaagag
    10801 cctctttgtc aaagttgtaa ccgtattgtg tagcttccca cttttgaact tccttaatta
    10861 agtcttcact ggcataggta taaccataaa ccagttggtc tgcgtaagtt tgcacggctt
    10921 ggtggatttc aggcaagact acaaagtcca tatccgctat ccaagctggt agaacttcac
    10981 tatccgtttc tgtttctttc catttatagg tatggtgccc taaacggttg ggcaggcttg
    11041 taaaatcata ttttcccatc tttgtcttat ccttctaagg cttggcgcaa atctgcaatc
    11101 aaatctctag catcctcaat cccaatagac aaacgcaaga ggtcatctgt caaaccataa
    11161 gaatggcgta cttctgctgg aatatcagca tgagtttgag tcgttggata agtaataaga
    11221 ctttccactc cacccaaact ttccgcaaaa gagaagacct tgagactgtt caaaatatga
    11281 ggaatgcgtg tttcatcggc tactttaaag gaaatcatgc ctccacgacc agtgtagaga
    11341 acttccttaa ctgctggaga atccttcaaa aaggcaacca cttcttgggc gttagctgtt
    11401 gagcgctcca tacgaagaga caaggtcttg agaccacgaa gcaactggta gctgtcaaat
    11461 ggagacaaga ctgcccctgt tgtattaaga ttgtaaaaaa gcttctcgta tagttctaaa
    11521 ctattggtca caaccactcc agccaagaca tcattgtggc ctgctagata cttggttgct
    11581 gaatggagaa cgatatctgc tccatcttca atcggacgtt ggtagatagg gctatagaag
    11641 gtattgtcca ccaccacttt ggcaccctta gcatgagcca attttgctag tttttcgata
    11701 tcaaattcca acatcaaggg attggttggg gtttcgatat agagaacatc cacatccttt
    11761 tctaactcgg caatcaactc ttcttctgta ttggcatagg taaaatggaa atgaccttcc
    11821 tgctccactt ggttaaacca gcgaaaagaa ccaccgtaaa gatcacgcac tgccaagacc
    11881 ttacttccta ctggaaagac gctaaaggcc agtacaatag ctgacatccc tgagctagtc
    11941 gctagggcat agtctgctga ctcaatagcc gccaagactt cctcagcctt actacgagtt
    12001 ggatttttag tgcgcgtata gtcaaaccca gtagatcgac caaactctgg atgctgatag
    12061 gtcgttgaaa aatgaagtgg tgtcaccaaa gcacctgttg cctcatcaga cttgatccct
    12121 gcttgtgcta aaattgtgtt aatgtgtaat tccttgctca tacaattcct ccaaatctat
    12181 agtaactatt gtaccactta ttttcatcaa ctcattttct tcttttcaag agctagttat
    12241 agtttcaaac tatataaaaa gggagttttt cctgctccct ttaatagact ataaaatggt
    12301 gaatctcaaa agacaccttc actctatcat ttgctcctgc acaaaacgag cataacgctc
    12361 atgattttcc agtagttcct tatgagttcc tgagccagtg attttcccct cctctaagaa
    12421 gaaaatacaa tccacatctt ttaccgttga caagcgatgc gctataatca caaccgtctt
    12481 ctcctttagt acagaataga ggctactgat aatcgcatac tcagaatccg catcaagatt
    12541 agcagtggct tcatcaaata taagaatttc agcatctttt aagtaggctc tagctatttg
    12601 aagtctttgg cttcgccccc ctgacaagag tcgtccgcgt tcaccaactt cagtatctag
    12661 tccctctttc atggagcgaa tctcatcacc tagtgatact aagtctagca ctttcatcaa
    12721 ttcatcatca gttactaagc gattcaaacc gagacaaaga ttgtcacgaa tactgccaga
    12781 taagactgca ttattttgtg aaacccaagc gattttactt ctccattctt ttaagttaaa
    12841 atcatatata cttgattgct ccattagaat atctcctgaa agcggtttat aaaaccgctc
    12901 taacaaacgc acaatcgttg attttcctga tccagatggc ccaacaaaag caattttttg
    12961 ccccttgaaa attgaacaag taatatcctt taagacaggt cgattttcat cataaccaaa
    13021 atagacatgg ttaaaattca acccttgtcc tgataccgat tttcctccct caaatttttc
    13081 tttaggaact gcaagcaagt tctccagtgc aactgaagat cccttgctac tagaataaat
    13141 agttacaaaa ttagctatat tactaatagg attaagtaat tgaaagaggt aaatcaaaaa
    13201 cgaaaccaag gttcccacag atatatatcc tgcgctgacc cgataacccc cataggttag
    13261 catcacaact atagtcgcaa agataaataa gagagcaaac ggggtctcaa aagaagtaac
    13321 cctatctgat ttcagtgaat tgttttgtac cctttcaata caattatcca aaacatcctg
    13381 tacacttttc tctgcttggt tagtcttaat taattcatgt tcttgaatct tttcagtcaa
    13441 ttgccctgtt aaaaatccga tttcctcctg taaacgacga ctatactttt cactgatatt
    13501 ggaaaggggc aagataataa acatcataca aggaagagtg atgaataaaa gtagagaaag
    13561 attccaatca agactaaata agactacaat ggaaccaagt accataacta aactcagaat
    13621 aatatttggg aaagtcgtaa ttaaaaactc acgaatgaca ctcgtgtcat tgacaatggc
    13681 agaagtcaac tccccacttt ggctcttatc aaagaaggat ttctctgcat aaatcaaccc
    13741 ctctatcact tttttcctga tttttgctat ctttttttca cccgattgac taaacagata
    13801 gtaaccaata gaagaaaaca aggcttgacc aataaaaatc aaaaacgatt gaaatacttt
    13861 ggaacctata ttttcaatag aactcccatc tattaaacct tttaagataa ggggaagcaa
    13921 caaagcaagt agactagaca gaacaaggaa gaaactcccc ataatcacct tagtatctac
    13981 tcttaataat tttaatttca taaatactcc ttataatatt tcaacggata aagtcgggaa
    14041 taactcaatt tgaggataaa atctaataaa tcttcctata acaaaacgca taacatctag
    14101 gattttatat acctgatatt atgcgttttt aagcacaaag acttcttaca caaacttatc
    14161 tacaattaga ttttatttga catgttttgc caattcttct tgggcttttt tattggattc
    14221 ttctttttct ttcaaccatt tttctctggc ttttgcatat tcgtctgttg tgacaatctt
    14281 atcttgtact ttgaggtatt tatatgattc aacccctttt gtaccggtta aaccataggc
    14341 agcagcaaat ggtacggttc ttctcaatga tggtgttccc ccacgcgaaa cacttggaag
    14401 aactaaagaa ctatcaatca accaagcttg aatatcagca tatttctcat aacgtttggc
    14461 tggatcttgc tctttattag cttcttccaa catttgagta tagacatcca gtccaacttc
    14521 cttagccttg tcattggctt ctccaggctc tagtccaaga ttttgtagaa ctcctccact
    14581 attagtatta aaaatatcga gataggttga cgggtcttga taatcaggtc cccaaccgcc
    14641 atgatataaa tcatagtctt tctgagcagc tgtttgagca aagtagcctg aactgtcaaa
    14701 ctcatctgat gttaattgct gaatgtcaat cactacatta tcagaaccta aaacagattc
    14761 aattgattgt ttgatagaac taactccttg tatgcctact ttatctgtta cttccacagt
    14821 cttatccaag tggattggga attgaacacc ctttgcttcg agttctttct tagcttccgc
    14881 aaacttagcc ttggctttct caggattgta gtaagggtct tgaccatccg caaagttgat
    14941 accttgccat tccttaccat agttgaccat cttagaggct acaacttcac caaagtcttt
    15001 tcccttgata ctgacaaagt ttggaggaac cactaggtta cgcaaaatct ttgttgcacc
    15061 ttctttccct tcagactgag ccccataaga tgttctgtca aaagcaaaat tgatagcctg
    15121 acggaagttt ttattgagaa ctgcttcctg agtcgatttc ttttcaatgt cacttgtttt
    15181 agaagtataa ttgtaagact tcctatctag gttaaaatta aagaaatatg aagttgaatt
    15241 ttgcatacta tagatgatat tgtttttgta tttttcttta atcccttcat agctggagct
    15301 gttaggaaaa agacgagccg tagtataagc accagctgta aaattacgtt ccagtgattc
    15361 ttggtcgcta ccatcatagt aggtcaattt cacatcgtct acaaagacat tcttagcatc
    15421 ccagtaatta gggtttttct tatattcaat agcagatttt gagacaagtg ctttcatcaa
    15481 gaaaggtcca ttgtacaaaa tactagatgg atccgccttc ccaaaatcat ccccttttga
    15541 tttcaggaaa tctgcattaa caggaaaaag tatcgttgca agtgtttttg aattccagta
    15601 aagctctggt ttaaccaaag tatattgaac cgtttggtca tcaagtgcct tgacaccgac
    15661 agttgaaaag tcgcttgttt taccagtgat atagtcatcc aaaccagcaa cagagtcctg
    15721 cactagatac aaggcttctg attttttatc agctgcatat tgcaaacctg tcacaaaatc
    15781 ctgggcagtt acaggcgcat attcttctcc ctcagaagta aaccacttgg catccttacg
    15841 aagtttgtag gtataggtca aaccgtcctg agaaacagtc caatcctctg ctaatgatgg
    15901 aataatattc ccatattggt cattttctaa taacccgtct accaaatttg caacaatatc
    15961 ggatgttgct gcgcggtttt ctgctagata gttcaagcta gatggatcac ttgaataaac
    16021 atagttgtag gtttttgacg ccgtgctaga atttccacac gcgctcaata aaactcctgt
    16081 acccaggaca agacctgcca aggttagata tttgctctta gactttttca tttccgaaac
    16141 ctcctgcttt aaatatttgt tttattatac aactcttggt ttgtttagtc aattgttttt
    16201 tccaaaaaat caaaaaaaac ctcattttct atttttgaaa gataatttta gctattttta
    16261 cgctaaaaaa ggaataagtt tcaagttctc ctaaaagatt gttcaactta ttccttttat
    16321 ttataaatgc taccttacga aagcttaaat tttgctcgca ggcgatctgc ttgggctttt
    16381 cctattacct tatctaacaa ataggtacgc agactcataa ccatataaag tccacccccc
    16441 atggcaccga caagagctac ataaaagaag ctccacaaac gtccacttgg ttggaagaaa
    16501 aatcctaaca gccactggat ggttcctatt aacagaaaca tgactagggt cagcaaactg
    16561 attaaaatgg ttcgcttcaa aatcaccttg cgcttgacac cagttacttt acaaatatcc
    16621 cgatacatca agacgttagg aatgatgaga gcaatggttg ttgaaatcaa aggaccataa
    16681 ctgtggaaga gggcgatggt aggtagttgc aagactagct tggcaataga accatagata
    16741 aaatagagaa cggcctttcg gttgcggaac atggcctgaa gcattggaga caagaccatg
    16801 tacaagccta aaataataga ctgcaaaact gcaaagacaa ataagcccag agccaaacta
    16861 tctggcttac catagaagac cgtataaaga ggttctccta ccataaccac tccaaccgtt
    16921 gctggtagca agaacataaa gagtagggtg agactgtcct gaacgagacg agaagctgct
    16981 ttcaagtccc ccttgacata gttttccgtc aaaagtggca aaccaacact cccaatcgaa
    17041 acccctacag aaatcaaaat catcgtgatt ttattaggat tggctgagaa ataagaaaac
    17101 atgacaacca agtcctcatt gctgtagttg gtaaaccagc tcatactatt gataaaggtc
    17161 agctgatcca aaatctggaa gagctggatg gcagaccctg tcaggataaa aggaatggct
    17221 tccttagtgg tatcaaccaa gagacgctta ctgttaatct tatctcctgt ttcaaagact
    17281 cttttgagtg aaccttcttg ggcaaggaaa taaatcaaga ctgcaaaact ggctaccata
    17341 ccgacaaagg cagcaaaggt tgattgggta acggctgcta gataatctcc tgaaccgagc
    17401 ttcataatga taaaggttgc taggagcatc cagataacac gaatgacctg ctcagcaatt
    17461 tggctcatgg catagggttt gaggttattc atcccttgga aaaatcctcg gataacactc
    17521 atagacggga aaatcaagac tccccaagcc aagctttgca tgattgggat caagtctttg
    17581 cccacgccag acaagtctgc tagccaagga gcaaagacat acaagactaa agcaaaaacc
    17641 aggcctagtc ctgtcataaa gcctaagaag ctccgaatca gggcaaagct atgctcttct
    17701 tctcgcatgg tattatactt ggcaacttgc ttggccaccg caactggaat ccccgctgtt
    17761 gaaaccaaca agaaccaagc atagatattg taacccatgg taaagagacc atttgcctta
    17821 gctgcataag cccccatcca gatgtaccaa gggataatat aaacagcccc gagtaggcga
    17881 ctgataaagt tactagccgt tagccaagca gtcccccgta acatctgggc ctgctggtga
    17941 ttgttttcgt gcgacataga ttcctcattc aattttgata gctaggaaaa actccttatc
    18001 ttccattata aacttttcct tgttacttgt aaatttacga ctttcggttt acaatagaaa
    18061 gtatgattaa gattgaaacc gtattagata ttttaaagaa agatggcctt tttcgagaaa
    18121 ttattgacca aggtcattac cactacaact acagcaaagt tatttttgat agcatcagct
    18181 acgacagccg aaaagtaaca gaagacactc tttttttcgc aaaaggcgct gcctttaaaa
    18241 aagaatacct tctttctgct ataacacaag gattagcttg gtatgtagct gaaaaggact
    18301 acgaagtcgg tatccctgtc atcattgtga acgatataaa gaaagccatg agtttgattg
    18361 ccatggagtt ctatggtaat ccacaggaaa aactcaaact ccttgccttt actggtacta
    18421 agggtaagac aacagcagcc tatttcgcct ataacatctt atctcaaggg catagacctg
    18481 ctatgttgtc gaccatgaac acaactcttg atggcgagac tttctttaag tcagcgttga
    18541 caacccctga gagtattgac ctctttgaca tgatgaatca ggctgtgcaa aatgaccgta
    18601 cccacctcat catggaagtc tccagtcaag cctatctggt caaacgtgtc tatggtctaa
    18661 cctttgatgt gggagttttc ctaaatatca gcccagacca tatcggcccg attgaacacc
    18721 ctagctttga agactatttc taccacaagc gtctcttgat ggaaaatagc cgagcagtca
    18781 tcattaacag tgacatggac cacttctcag tcttgaaaga acaggttgaa gatcaagacc
    18841 atgatttcta tggtagccaa tttgataacc aaatcgagaa ttccaaagcc tttagctttt
    18901 cagctacggg taaactcgct ggagattatg atatccaact cattggcaac ttcaaccaag
    18961 aaaatgcagt tgctgctgga cttgcttgtc tctgtctcgg agcaagtctt gaggacatca
    19021 aaaaaggcat cgctgcaacc cgcgttcctg gtcgtatgga agtcctcact cagaaaaatg
    19081 gagccaaggt cttcatcgac tatgcccaca atggggatag tctgaaaaaa ctcatcaatg
    19141 tggttgaaac tcatcaaacc ggaaagattg ctctggttct gggatcaaca ggaaacaagg
    19201 gagaaagtcg tcgtaaggac tttggcctcc tcctcaatca acaccctgag attcaagtct
    19261 ttctgactgc tgatgaccct aactatgaag acccaatggc cattgcagat gaaattagta
    19321 gctacatcaa tcatcctgtt gaaaagattg cggatcgcca agaagccatc aaggcggcaa
    19381 tggctatcac aaatcacgaa ttagatgcag ttattattgc gggtaaggga gccgattgtt
    19441 accaaatcat ccagggcaag aaagaatcct acccaggaga tacagccgtc gcagaaaatt
    19501 atttataaga atagaaaaaa tcaagggaaa atgaaaccct tgattttttc ctattattta
    19561 gtaaaaacgt ttttcaaacc ttcaacggca ccttctacag caccttttgc gtcttctaca
    19621 acgtcttttg ccttagcaac tgttttttca acagctcctt caagttctgt cttgctgtct
    19681 ccagtaactt taccaaaacc ttctttgaca gcgcctgttg cttgttccaa tttgttttca
    19741 agtgacatat gattgtctcc tttagtttat tccgatatgt gttaccggtt acatatagtt
    19801 tataccgaat actaaggaaa gtcaaacaat gtgctcagaa acaagaaatc acgctaagta
    19861 gaaagttaat ctctccttat caaaatcgat agccaactca tactttctat cttcattttg
    19921 cacaatatag cctaagacaa ccaaactgtc cacaaagata tcacggcatt tctgcataag
    19981 gtggtctttt ttgagaaatt tcaacaaaaa agccgtcata tacttgagtg catactcagg
    20041 attaacatct cctaaaatgt catagagctc ctgctgtttt tctgtcaaag gatactgctg
    20101 tttgaccttg taaaaataat tggacagggt cattttaatg cgcgcaaagt ccgtcttttc
    20161 aactaaaata gctgcattga tttgattgcg caattccgtc tcaaaactct gctccaacaa
    20221 ggcttgatag accggactag cttctctgac aaaaatctct tgatccagtt caagactatc
    20281 aagtgattca agcgtaggaa aattgaggta atagcgctta ttttcacgta gaatcaagcc
    20341 tgcctttata tactcttcca tgagtttatc aactgcaaca tctggaaatt gagccttaat
    20401 ttcccgtaga atcacatcct catactggtc cagatagcgg atcaattctc caaaaatggc
    20461 tgtctcgtca aacgagatgg attaaaaatc tgaatcatga agattccttt ctttacattg
    20521 taacagaggc gatgctgcca actgactagg attggtacca gcttggttca gaggaacagg
    20581 cagacctagt tctatgtaat actccctcca aaaatcacta atctcctgct ccccatctcc
    20641 aaatttcata ggaatagttt caaaaatagg taggatttct gctatatact gggagcagta
    20701 gaaaccagct gcatctggat agaaagaagc attgtagggt gctccaagat gtttgcaagc
    20761 tctttccttc accgactgga tatccatttc tgggtaaaca tagaggtcgt ataaatgatt
    20821 ggactcaaag aagtctgccg gttcttgaca gacaacacca gcctgtccac tagcatgata
    20881 aatcatccca tccaaataaa tggcaacatg gctatagtta cctgtggaag tctggatggc
    20941 ctgtcccatg tctgacccat ctctcacaaa aatcaaatcg ccattttcta acatacttca
    21001 ctcctagaaa aaaggagccg aaactccttt cgatataagg caaactagac tttccgattt
    21061 tgagctgaca cccaaaatct tacgcattaa agctttcagt caattgaggt accacttgtt
    21121 tcttacgtga aacggcacca gcaaggaagg catgattgtt ttcaagtttg aagttgaaag
    21181 ccgcttcgac cttgtccata ttggcaccaa gagccaagat ttctgagttt gagttgacga
    21241 tatctgtaat catcaagaca aagtcagagt agccgtttga ttcgttggca gcttgcattg
    21301 cagcttcaat ttctgcttgg cgttccaaaa cttcagcgat gtcaactgtg ttcacttggg
    21361 caacacggac attatttccg ttgagttcaa aagtcttagc atcgatatca atcaattctt
    21421 cagcagattt gctagccaag ttggtaccag ctttcaacat tgccaaacca tattcttcca
    21481 agttcacacc agccaattca gccaattcag gagcaatgat tttatctgtt gggtgtgttg
    21541 ttggtgattt caaaagaagg gtatctgaaa tcaaacctga aagcatcaaa cctgcaatct
    21601 ctttaggcac agctacacca tgttctttga acatacggta aacgattgaa gacgctgatc
    21661 caactggctc caaacgcatg taaagtgggc ttgcagtttc aaagttagcc acacggtggt
    21721 ggtctacaac accgtaaact tctacttcag cgatatctga tacagattgt tggaattcat
    21781 tgtggtcagt caagataact tgctctgccc cctctgcttt ggcagaagtg ataacacgtg
    21841 gtgcttccac accaaaatag ttcaagacaa aggctgtttc ttcatttgga gttccaaggg
    21901 caacagcttc cgtatccaaa ccgtaagctt cttttgcaag gtaggcaaaa gctacagatg
    21961 atccgatggc atctgagtct ggattttggt gaccaaatac tagaatcttg gacatgataa
    22021 tacctcattt tgtttatttt ctttattgta gcattttttt cgctttttga caaaggtaag
    22081 aggagtcaaa ggactcccca cgattcttca aaataactga gtaaatttct atcttgattt
    22141 tcagataaaa attcttcctt ctgtggcctc ttcttacgct tgagaagagc ttcagccgac
    22201 atggcttctt ccttactggc aaaaccttga gcatagataa gtttgactgg caagcgtgct
    22261 cgtgtatatt tggctccctt cccactattg tggatagcga ggcgtcttct cacatcagtc
    22321 gtatagccta tatagtagga tccatcacga cactccagaa cgtacatata agccttatga
    22381 tccataataa atctcttcga tttcgggcgt ataagagcca tcatcattgt ggacaatcaa
    22441 aggaggtaag accttaaagc cacttgttga gccatccttg atcgcctcaa tcaaaagcat
    22501 attggcttcc ttttctcttt ttggataaac aaactgcagg cgcttagggg ctagattatg
    22561 tcgttttaac gtatccaaaa tatccagaag tcgatcagga cgatgaacca tggccaaacg
    22621 cccattagac ttgagaatac tctgggcact acgacagatt tcttccaaat tagtcgtgat
    22681 ttcgtgtcga gccaagagat aatgttcact ctcgttcaga ttagaataag gatccacctt
    22741 gaaatagggt ggattacaca aaatcatatc caccttactc ccctgaatgt gagcaggcat
    22801 atttttcaaa tcatcgcaga tgacctgcat ttgctcctct aatccattca aacggacaga
    22861 gcgttcagcc atatccgcca aacgctcctg aatctcaaca gacaatatct gtgcttgagt
    22921 acgagtgcta gcaaaaagcc ccactgctcc attcccagca cagaaatcca caatcaaccc
    22981 cttcttagga aaacgtggaa atcgtgataa gagaacacta tccaccgaat agctaaaaac
    23041 ctctctattt tgaatgattt tgatatctgt cgaaaagagc tggttaatgc gctctcctga
    23101 ttttaataat tgttcttctt ccatggtcct attatagcaa atttatatta acatcacaaa
    23161 aaatataaaa ctctaaacta cttcgtcttt tttaaatggt gcagggcttc tccagtccag
    23221 attggtaaca ttcgtcgaaa gggagcaaaa ccgtagttaa agcggtcgct tgaaaagcgt
    23281 ctccgtctag gaaactggta cttttcttcc tccaaagtgc ggatagaaag actggctttc
    23341 cccgtaaatt catctaaatc cactacctga acttgaacct cttcatcgac tttcaaggtt
    23401 tcatgaatat tttcaataaa tcctgtccga atttctgaaa tgtgaatcag ccccgtatca
    23461 cccatctcta actcaacaaa ggcaccgtag ggctgaatcc ctgtaatacg cccctttagc
    23521 ttatcaccga ttttcatctt agtcctcgat ttcaatagtt tcaattacaa catcttcaac
    23581 tggcttgtcc atagctcctg tctcaacagc agcaatggca tccaagacag cgtaagatgc
    23641 ttcatcagct aactgaccaa aaaccgtgtg acggcggtct aggtgaggtg tcccaccttg
    23701 attggcatag atttctgcaa tcggttctgg ccaaccacca cgagtaattt ctttcttaga
    23761 ataaggtagg tgttggtttt gcacgataaa gaactggctg ccgttggtat ttggaccagc
    23821 atttgccatg gaaagagcac cacggatatt gtaaagctct tctgagaatt catcctcaaa
    23881 agattcgccg tagattgact cgccacccat accagttcca gttgggtctc caccttggat
    23941 cataaagtcc ttgataatac ggtggaaaat gacaccatca tagtagccat cttttgaaag
    24001 agatacaaag ttagccactg ttttaggagc atgttcaggg aaaagcttga tacgtaagtc
    24061 tccgtgattg gtcttaatag tcgcaagagg accttctact gtttcaatgt ctacttgtgg
    24121 aaaatgcaat tctttttcta ccataccaaa tacttctaag gcatcaaaaa tgccatcttc
    24181 ttctaatgtt tttgtaatat aatctgcttt ttctttgatt ttatcatgag aaattcccat
    24241 ggcaacgctg attccagcat aatcaaagag ttccaagtcg ttgagaccat ctccaaaaac
    24301 catgaccttc tctggtttca agccaaggtg ttccacaacc ttttccaccc ccgtcgcttt
    24361 ggagcctgaa atcggcacaa tatcagacga atgttgatgc caacgaacca tgcgaagttt
    24421 gtctgagaga ctgtcaggca agtgcaagtc atctccctta tcttcaaaag tccacatctg
    24481 atagatatct tctttttcat ggaaatcggg atctacatct aagtcgggat aaattggatt
    24541 gatagcttca ctcatcatat cggtgcgagt cgacaacttg gcatcatgac tcccaaccaa
    24601 gccatactca attccttctt gcttagccca agagatatac tcctcaacat ctgacttttc
    24661 aatctgatgc tgataaatga cctgaccttt tttatcttcg atataagctc cattcaaagt
    24721 tacaaaaaag tcaggcttga gatcacgaat ctctggaaca acaccaaaaa tgccacgtcc
    24781 agaggcgatt cctgttaaaa ttcctttttc acgcaactgt ttaaaaacag tgggaattgt
    24841 agttggaata aaccctgtct ttgaattccg caatgtatca tcaatatcaa aaaagacaat
    24901 cttgatcttc tttgccttgt atcttaattt cgcgtccatc tcactacctc tttcaatcta
    24961 actctttcca ttatatcata aagtaggcaa atcccctatt ttcaaaaagt ttatcatttt
    25021 tattttaatt tcttggatga gaaaagagac atatttatga aaaagctcca tcgtgctttt
    25081 aatgtgttct cttgttttca aactcgtaaa aagggagcca ctgagcctaa ctcgctctct
    25141 catttcaaat cttgtgaaaa aagacccgtt ggggtcttaa ttcgctttct tgttttcaag
    25201 ctcatgaaaa agagacccaa tcgggtcttt tctttaatct tcgtttacga aaggcatcaa
    25261 agccattacg cgagcgcgtt tgatagctgt tgttacttta cgttggtttt tagctgaagt
    25321 tcctgttaca cgacgaggaa ggattttccc acgttctgaa acgaaacggc taagaagctc
    25381 agtatctttg taatcaacat attcaatttt gtttgctgcg atgtaatcaa cttttttacg
    25441 gcgtttgaat ccgccacgac gttgttgagc catgtttttt ctcctttata agtttagttg
    25501 tccattagaa tggtaaatca tcatctgaaa tatccaatgg gtttgttgct ccaaatggat
    25561 tttcattacg tgaaaagtct ggtactgaat ttgtaggtgc tgaatagttt gcagttggtg
    25621 cagagtaagc tccacctgtg tgaccctcac gcacactacg gctttccaac atttggaaat
    25681 tctcagccac gacctctgtc acgtagacac gttgtccttg ctggttatcg taactacgag
    25741 tctggatacg acctgtcacc ccgataagtg agcctttttt agcccagtta gcaagatttt
    25801 cagcctgttg gcgccacata acgacattga taaaatcagc ctcacgttca ccattttgac
    25861 tcttaaatgt acggtttact gcaagagtaa aagtcgcaac tgctacattt gatggggtat
    25921 aacgcaactc agcgtcacgt gtcatacgcc ctacaagtac aacattgtta atcatagttt
    25981 accttcttac gcgtcaattt tgacgatcat gtgacgaaga atgtcagcgt tgatttttga
    26041 aagacggtca aactctttaa gagctgcatc gtcatttgct tcaacgttaa cgatgtggta
    26101 aagtccttca cggaaatctt ggatttcgta tgcaagacga cgtttttccc aagtttttga
    26161 ttcaacaaca gttgcaccgt tgtcagtcaa aatagagtca aaacgtgcta ccaaagcgtt
    26221 tttagcttct tcttcaatgt ttggacgaat gatataaaga atttcgtatt tagccattga
    26281 tatgttcctc cttttggtct aatgacccca agactttgca aggggtaagt gaggttcgct
    26341 cacaataaac tattatacta gaaaaaattt ttttacgcaa gtaaaaacac tagaattcga
    26401 aaaaacgcca catgggcgtt ttcctgttct tatggtttga tacggtgcaa catacgtggg
    26461 aatggaatag cttcacggat atgttttgtt cctgctgcga aggttaccat acgttcgata
    26521 ccgataccaa atcctccgtg tggaactgta ccgtatttac gaaggtcaag gtagaattca
    26581 tattctgtac gatccatgcc aagttcatcc atcttagcga caagggcatc gtaatcttcc
    26641 tcacgcatag acccaccgat aatttctcca tagccttctg gagcaagcaa gtctgcacaa
    26701 agcacgcgct ctggatttcc aggaactggt ttcatgtaga aggccttgat ggctgctgga
    26761 tagttcatga caaatgttgg cacaccaaag tggtttgaaa tccaagtttc gtgtggtgac
    26821 ccaaagtcat caccatgctc aagatgctcg tagtcagcat cttcatcatt ttcatgctct
    26881 tgcaagaggt caatggcttg atcgtaagtg atacgtttga atggctctgc aatgtagcgt
    26941 ttcaagagtt ctgtatcacg ttccaaggtt tccaaggctt gaggcgcgcg gtcaagaaca
    27001 ccttgtagaa gagctttcac ataagcttct tgcaagtcaa gcgactcatc atgtgtcaag
    27061 tatgagtact cagcatccat catccagaac tcagtcaagt gacggcgtgt ttttgatttt
    27121 tcagcacgga aaactggacc aaagtcaaag acacgaccaa gagccatagc ccctgcttct
    27181 aggtaaagct gacctgattg gctcaagtag gctggcattc cgaagtagtc agtttcaaag
    27241 agttctgtag aatcttctgc cgcatttcct gaaagaattg ggctgtcaaa cttcataaaa
    27301 ccgttcttgt caaagaactc ataagttgca tagataatag cgttacggat ttgcaacaca
    27361 gctacttgct tacgagagcg tagccacaag tgacggttat ccatcaaaaa gtctgttccg
    27421 tgttcttttg gtgtgattgg gtagtcttga gattcaccga tcacttcgat gtctgtgatg
    27481 tccaactcat agccaaattt agaacgttcg tcctctttga caatacctgt cacataaaca
    27541 gacgtttctt ggctcaagcg tttgataaca tcaaacttct caagtcccac ttcttcacca
    27601 aatttttcga caaagtttgg tttaaaagcc acaccttgaa agaaggctgt tccatcacgc
    27661 aattgtaaga aagcgatttt cccttttcct gatttgttgg caacccaagc gccaatcgtc
    27721 acttcctgac caacatagtc ttttacgtca ataatcgtta cacgttttgt cattattttt
    27781 ccttttcttt tttattcttt atggcaaacc acctctatat tgttcccatc caggtcaatc
    27841 ataaaagcag catagtaaat cggatgctca cttcgataac caggagcccc attgtctcgc
    27901 ccacctgcct ctaagccagc ctcataacaa ggctgaactc cttccttatt ttctgctaaa
    27961 aaagcaaaat gaacaggatc ttgtgttccc tgagtcagcc aaaaatcacc accaggatga
    28021 gggctgttcg gggatagaaa actaattaga gaactagtct taaaagccat tttatagtcc
    28081 aaaggagcga gaaaactcct ataaaatcct tctgaaattt gtaaatcctt taccttaatc
    28141 tcaaaatgat caatcattct cactacccat aaatgctttc aagcgttcga ctgcttcttt
    28201 aagcgtgtct aggtctgtcg catagctgag gcggacattt tctggtgctc caaatccagc
    28261 tcctgttacc aaggccactt cggcttcttc taagatagca gttgtaaagt ctgtcacatc
    28321 cgtgtagcct ttcatctcca tggccttttt gacatttggg aagagataga aggccccttg
    28381 cggtttgacc acttcaaatc ctggcacctc tgcaaggagg ggatagatgg tattaagacg
    28441 ttcctcaaag gcctgacgca tgctttctac agtatcttgc tcacctgata gagcctcaac
    28501 tgctgcatat tgggctactg ctgacggatt cgaagttgtt tgacctgcaa tcttggacat
    28561 ggcagcgata atgtctgctt ctccaacggc ataaccaatc cgccaaccag tcatggcata
    28621 ggttttagac acaccattga tgaccactgt ttgcttgcga atcgcttccg ataggctaga
    28681 aatcggtgtg aactcatgac cattataaac caagcggcca tagatatcat ctgctaggat
    28741 gagaatatca ttttctacag cccagtttcc aattgccaag agttcctcac gggtgtaaat
    28801 catacctgtg ggattagatg gcgaattcag caccaaaacc ttggtcttgt cagtgcgagc
    28861 tgcttctaac tgatctacgg tcaccttaaa gtgattgtct tccttagtag aaacaaagac
    28921 gggaacgcct tctgccatct tgacctgatc tccatagcta acccagtatg gggttgggat
    28981 gatgacttca tcacctggat tgaccacagc cataaagaag gtatagagag aatatttggc
    29041 tcccgcagcg actgtcactt gatttgacgc tacagaatag ccgtaaaagc gctcaaagta
    29101 gctattgacc gccgccttaa gctctggcag acctgaggtt actgtataaa aagaagcacg
    29161 cccatctcga atcgatgcaa tggcggcatc ttggatattt ttgggagtag tgaaatctgg
    29221 ctcacccaag gttagagaca aaatatctct gccctcagcc ttcagtgctt tggcacgggc
    29281 tccagcagcc aaagtcacac tttcttccat ttctaaaaca cggttggata atttcatagg
    29341 ccctccttgt tgaccaatgc tcctgtttca aaatctacta gataaaaatc agatcctgac
    29401 ttgacttccc agattggctt atcttgataa cgaccaaaga taatcttgtc aatttcgcca
    29461 gctccctttt ccttagaaac cgtttctgct ttttcttgtg aaacaccctg atttagctga
    29521 taaacgtaaa tcttatgatc atctttacca atcaggacag caagcgcttc ttgctgttta
    29581 ttacgaccaa gaacgctgta ataagattcc aagccattgt ataaatcaac ctgatcgacc
    29641 tgctctaatc ctgcatactg ctgagctaat ttttctcctt cacttttagc tgtttgatag
    29701 ggtttcatgc taagagaaac catatacaga aaggaagcac tgataaccac aaacaaaatc
    29761 gtcatcccta gaccatactg ccacagtaga ttattttttg ctttgttttg tctttttttc
    29821 actcgtctat tttaccatct attaagcttt attacaagtg aatataagaa tactcttcga
    29881 aaatctcttc aaaccacgtc agctttatct gcaacctcaa agctgtgctt tgagcaacca
    29941 attctatttc tcccttcaaa caaaaccgat tttgaaagtg aaacagttct tactttttca
    30001 gtcacaaatg attagagttt ccgaaatttt acaattttca aataaactct gagcaaattt
    30061 cttgcaagtt cttttgtttt gttgtaatat attttataac aacgagagag ttctcgaaat
    30121 tttaagaaaa aggagacaca tcatgtctaa aaaagtatta tttatcgtcg gatcactacg
    30181 tcaaggttct ttcaaccacc aaatggcgct cgaagctgag aaagcacttg ctggtaaagc
    30241 ggaagttagc taccttgatt attcagccct tcctctcttc agccaagatt tggaagttcc
    30301 aacacatcca gctgtagctg ctgctcgtga agcagttctc gttgcggatg ctatctggat
    30361 tttctctcca gtctacaact tctctatccc tggtacagtg aaaaacttgc ttgactggct
    30421 atctcgtgcc cttgacttgt ctgatacacg tggcgtttct gcccttcaag acaagtttgt
    30481 cacagtatca tctgtagcca atgcagggca cgatcaactt ttcgctatct acaaagacct
    30541 cttgccattt atccgtacac aaggcgttgg tgatttcact gctgcacgtg ttaatgactc
    30601 tgcctgggca gacggaaaat tggttcttga agaaacagtc ctaaactcac ttgaaaaaca
    30661 agctcaagac ttggtcgaag ctatcaagta actaacactc aataaaaatc aaaaagcaaa
    30721 ctaggaagct agccacaagc tgctcaaagc actgctttga ggttgtagat agaactgacg
    30781 aagtcagtga catatatacg gtaaggcgac gctgacgtgg cttgaagaga ttttcgaaga
    30841 gtataacata ataaaagcga acaagactac ttttctgaca ctcagaagac tagcttgttc
    30901 gctttttttc tcatttataa actaaaacag ctgatgatac atattgccaa atacaaaata
    30961 tctgatttct atacttcctt tacaaaaact aatccctgtg gttgtgacaa atcttctcgg
    31021 taaacaaatc cagcaaagtt caagcgacgt gcttccccca cagtttgtac ttgattttct
    31081 attaaagctg ttagaaaggc cccgcgcgct ttcttggaga tagttgagtg aatcttcagc
    31141 tgaccgcctc tatcctccat gaatttgaag gtcaccatct ttgctctgat ttccttagaa
    31201 aatacagtct caaactctga tgacaagaga gagaaaatca cttcttcctt cttcagagct
    31261 tcatcataga ctgccttcca atggctcttc aaagccttac cagcgacttt taatttcatc
    31321 aaaaaatcca aacggtgagg agccatgggt gacaaggctg gaacaacacc gtacaaagcc
    31381 gaggtaatga agacatgatt ttcaagataa tcttgttccg cctcggtcag cttatctctc
    31441 ttaatgttgc ggtacataag cccatcaaaa agtttcaagg ctggatagtg ttgagcagtt
    31501 tgccttttca aagcttggat attttgaaat tcttccgccg ctttctcagc tgataccttg
    31561 tagaaactct ccaattgact ggcagaatag agagccaagg catcaagcac ggcctgactt
    31621 tctggtttta aaggaattgc ctcgatactt ggcaagtctg tgttcatttc ttttgctgtt
    31681 gggattaaaa ttttcatatt gatagtgtag catatttttt agccacaacc aagaaattca
    31741 tttgaaaaac ctcggtttga ccgaggtttt tctatttatt tgggccatcc taaccagaca
    31801 gccacgagaa caagggctgt gccagctaaa cttgttaaga tagataagaa tttatctttt
    31861 ttctccttga actgagaaaa acctatcttc aaagcgagca gtccgagtag cattgaagca
    31921 accatcaaat aaaaacccat ttctttgtcc tccattaggc ttaatttacc ttattataac
    31981 atatatttct taaataaacc ttttttatac tcaatgaaaa tcaaagagca aactaggaaa
    32041 ctagccgcag gctgctcaaa acactgtttt gaggttgcag atagagctga cgtagtttga
    32101 agagattttc gaagagtatt attgtacttt aaaggtcttg agatagttgt cttttcctac
    32161 ttgaccttcg aaggttttac cattttcaag gtaaggaagg tcatcggata ctgaagcctt
    32221 taccttgtat atcttgccat caactttaaa gaagtagaca gtgtctccct tgataacagc
    32281 tgatttgagg tctgctacta ctcccttgat gctttctgtc gttgcattgt caatttcaag
    32341 gtcgttttta ttggcatact tgctgagcat ctcttccact gtagtagcaa cgataacatt
    32401 ttggtactcg actgcgtcta ccagggcgta ctctttgacc aagccagcat tgtcctttaa
    32461 gcccatgatg tagagaggct tgtcattgag gttgatgagg attgggaagg ttgctttgta
    32521 ggatttctcc tgaacagcac cttctgctga ttcacgggct gattcttctg tcgcagaagc
    32581 caagctatac ttagtgattt ctcctgttcg catattttca aggatgaaac caagattact
    32641 ctcatccgca ttagccgacg tcacacctgt gtagagatag atgtcattac cgatagacaa
    32701 gtaattatag cccttggtag tctgggtcac gtttttcttg gaaatcatgg cattcaagaa
    32761 accgtccttg tacttgccgt tgtagttaat ttgctcaatg gtttcctctg ctggatagat
    32821 cctgtccacc cattctggaa catctgataa gctgtattcc ttggtttctc catttgtagc
    32881 atccaagata atgactgaag caggacgagg aacagcaagt ccaaattgct tttggtaaac
    32941 cgttgctaca tagaaaggat tgccctcatc gtccacctca aaagatggag ttttaaagat
    33001 tttggtcggg tacttcaagc gcaggtgacg tttgacatca cggttaaaat actccgagtc
    33061 tgaatacttg attggtgtct tcaagtccac caaatccgca tttccagtta ccatgtccac
    33121 cttaatatac tcaccgattc ccttggcttg attgttaaac catttgatag ggtctgcata
    33181 ttctagtggt gtgacccgat aaggtttccc atcaattgtc aattgggtat aggtatctgc
    33241 cgctacgtat tgcgacacct tatcggttag ggaacccaag tagcggtctc caattttttc
    33301 agcagtactt ctatctagga taggaacctt actggtgtca ctcttaggaa attcagtaaa
    33361 gtctttttcc gtaaccgtga ctacattggc ataattttta gcctgaaaca tgctggaagt
    33421 taccaaggaa accaaagctg ccaagagaag aattcctcca atcgaagcta acagaatttt
    33481 ccctaaccga ttgattttga aaccctcaag atttaaggca gcttccgcct taccgtggcg
    33541 cacatgaacc gttttgacaa ggtttatccc cttgctaaag ccaaataaga ttgccacaac
    33601 taacaaatgc ccacagagga agaagagaaa ttcccagctg gtcaggttaa ggggcggtaa
    33661 aaagatatac caggtcgttg cgataaaaat aagttcaaag actattcgtt tcatttgctt
    33721 tcctcctaaa tgattcgtcc ttccaagtga tccagctcat gctggcaaat ctgagctggg
    33781 aagcctgtca aggtaatggt ctgttcctgc cacttgctgt cacgataggc aacccttatg
    33841 gtttcataac gcttagttga tctcacacct accaaggaca aacagccttc ttctgcctca
    33901 taggatcctt caaaggacag aagcactggg ttaaacatga ccacgggaac caagccaaga
    33961 ttaaagataa tcacgcgctt ctgcacccca atcatattgg cagctagacc aacacaggta
    34021 tcacgatttg ctaagagtgt atcctgcaaa tctctggcaa gataaaggtc ctcctgactt
    34081 gccggctgag acacttgaga taaaaataag atatccttca caattttctt ttccacttcc
    34141 tcacactcct cttgcttttt actatattat agcaattata gcacaaaagc cgataactgc
    34201 aaaccctttc cctcaactgt agcaaaaagc catccgaaga tgactttttt gctatttaat
    34261 ttctgtataa gttacttcca agccacgctt aacagctgga cgattggcaa ttttttctgc
    34321 ccattttact agattttgat aacttgaggc atccaagaat tttgcagaac cttggtaaag
    34381 atttccttga actaactgtc cataccaaga ccagatagca atatctgcaa tcgtatagtc
    34441 attgcctgca atataaggtt tctgagccaa ttccttatcc aataaatcca actggcgttt
    34501 cacttccatc gtaaaacggt taataggata ttccaatttt tcaggagcat aattgaagaa
    34561 atgtccaaat cccccaccta gaaaaggtgc tgcacctgct tgccagaata gccaattcaa
    34621 aacttctacc ttttccacag gattacttgg taaaaaggct ccaaatttct cagcaaggta
    34681 aagaagaata tgagcagact caaagactct tacgttttca gtacctgact ggtccaataa
    34741 ggctggaatc ttggaatttg gattgagctt cacaaagtct gagccgaatt gatccccatc
    34801 catgatagca atcttataca agtcgtaagc cgcttcctta aaaccagctt ctagtaattc
    34861 ttccaataag atagtaacct tcacaccatt tggtgttccc agtgaataaa gctgaaaagc
    34921 ttgttctcct tttggcaagt tttgttcgaa acgggcacct gctgttggtc tgtttagccc
    34981 cgtaaaagct ccttgattac tagcttcatc ctgccatacg gtcggtaatt gatatgctga
    35041 catccgaaac ctcccttaaa tcgcattctt gtcaaaaccg agtttgcgtt gaataaactt
    35101 aacgatttcg acgatgataa tcattgagaa gcttccagcc ataacaattc cccattgtga
    35161 caagtctagt ttggttacgt ggaagattcc ttcaagcggt tctacaacga ttgttgccat
    35221 gagaaggata aaggatacca agatggacca gttaaaggtc ttagacttga atgggccaac
    35281 tgtcaagatg gattggtaga cagacttgac attgtaggca tggaagagct gaatcaaacc
    35341 aagggttgca aaggccatcg ttagggcatc tgcatgaata gcatgattgt cacccacatg
    35401 aactgggtaa gcaatcgcaa ggccataaac actcataaca agagctgctt ggagtacacc
    35461 ttgataaatg atagaactca aaacaccacc tgagaagaag cttgccttgc gtccacgtgg
    35521 tttatgattc atgacaccag gttccgcagg ttcaacacca agagcgatag ctgggaaggt
    35581 atccgttacc aagttgatcc acaaaagatg aaccggctgt aagacatccc aaccaaacaa
    35641 ggttgatagg aagatggtta atacttcagc agtattagca gaaagtaggt actgaatagt
    35701 cttttgaatg tttgagaaga ccttacgtcc ttcttccact gcgacgataa tagtcgcaaa
    35761 gttatcatct gcaagaatca tatcagaagc ccccttagaa acctctgtac cagtgattcc
    35821 cataccgata ccgatatcgg ctgttttcag agctggcgcg tcattgacac cgtcacctgt
    35881 catggcaacg actttacctt gtttttgcca agccttgacg atacgaacct tgtgttctgg
    35941 agacacacgg gcataaacag agtattgacc aacgactttt tcaaattctt catctgacag
    36001 ttcattgagt tcagcaccag ttaaaacgtg accttctgta tcgtttgcgt caatgattcc
    36061 caaacgtttg gcaatggctt ccgctgtgtc ttggtggtca cctgtaatca taatcggacg
    36121 gattcccgct tccttagcca cacgaacagc ctcagcggct tcaggacgtt cagggtcaat
    36181 catcccaatc aaaccagtaa aaattaaatc attttcaagc tcttcagaag tgagattttc
    36241 tggaatacta tcgataatct tataagcacc tgcaaggaca cgcaaggctt gatgagccat
    36301 ttcagaattg tttgtatgaa tgagatttgt aaccttctca tcaatcggag caatatcccc
    36361 agccttatca cgaagaagac aacgttttaa gagttggtct ggcgcaccct tgactgctac
    36421 aaggaaacga ccatctggca atgggtgaac tgttgacatg agcttacggt cagagtcaaa
    36481 tggcaattca gctacacgag gatatttctc taagaaacct ttgacatcat agcccttgtc
    36541 caaggcatat tggataaagg ctgtttcggt tgggtcacca atcaagttac cttccacatc
    36601 gattttcgta tcattggcca agacaactga acgaagtagt ggcatttcaa gacctagttc
    36661 aatatcatca gctgagtcat gtagaaccgc atcgtagaag actttttcga ctgtcatctt
    36721 gttcatagtc agcgtaccag tcttatcaga agcgatgatt tcagttgaac caagtgtttc
    36781 aactgctggc aacttacgaa cgatggaatg tcgtttggcc aaaacttgag taccaagaga
    36841 aagaacgatg gtaacgatag caggaagtcc ttctggaatg gctgcaacgg caagggcaac
    36901 agaagtcaac aactcaccaa gtggattttt cccttgaatg aagacaccca ctacaaaagt
    36961 aacaagggca atgaccaaga tagcataggt caagacctta gaaaggttgt tcaagttttg
    37021 tttgagtggt gtatcagtct catccgcatc ttgaagcata ccagcaatat gaccaacttc
    37081 agtgtacata cctgtattga caacaacacc catcccacga ccataggtta cgtttgagtt
    37141 ttggaaggcc atgttgacac ggtcaccaat accagcatct gtcgcaagct cgactgacaa
    37201 gtctttttcg actggtacag attcacctgt caaggctgct tcttcaattt taagagagtt
    37261 ggcttctatc aaacgtaggt ccgctggtac cacgtcacct gcttcaaggg caacgatatc
    37321 gcctggtacc aattctttag agtcaatctc tgccatgtgt ccatcacgaa gaacgcgggc
    37381 aactggacta gacatggatt tgagggcttc aatagcttct tcagcttttc cttcttggta
    37441 aacaccaaag gcagcgttga tgataaccac agctaggatg ataatggcat ctgcgatatc
    37501 ttccccacca gaagtcacga ctgacaagat tgctgccgca actaggatga taatcatcaa
    37561 atccttaaat tgctcgatga atttgaccaa gattgatcgt ttctcgcctt cttcgagttc
    37621 attgtgccca aattcggcaa ggcgcttttc cgcctcactt gatgacaaac cttgctcggt
    37681 cgcatccaca gcctgcaaga cctcttcagg gctctgagta taaaacgctt ggcgtttttg
    37741 ttcttttgac atgtgtctcc tccttgacat tgtgtgcaaa acagactctc tttctgtcat
    37801 atcttttcac gacaaacaaa aagagacctg ttaatcataa caagtctcgc tgtttaagat
    37861 agggccggaa agcatacttt tcagcataaa attcggaatg acgacactat cacaggtttc
    37921 tgccagctac tcccttgagt agtaccatta taccaaattt tggggagttt tcaaagagta
    37981 aaaactgcct tatttgaatt tttccttgaa aaccagtata atggtagaat gctatgtgac
    38041 tagaaaggaa gttgaatgaa gcaatctatc tcaaatctca agttagctga gcgtggagcc
    38101 attatcagta tttcgaccta tttgatcttg tctgcagcta aattagcagc tggtcatctc
    38161 cttcattcat ccagtttggt ggccgatggt tttaataacg tatcggacat cattggaaat
    38221 gtggccctct taatcgggat tcggatggcg cgccagcctg cagaccgtga ccaccgtttt
    38281 ggtcattgga agattgaaga tttggcaagc ttgatcactt ctatcatcat gttctatgtc
    38341 ggtttcgatg ttctaagaga taccattcaa aagattctca gtcgggaaga aacggtcatt
    38401 gatcctcttg gtgcaactct aggaatcatt tctgcagcga ttatgtttgt ggtctatctc
    38461 tacaatactc gcctcagtaa gaaatccaac tccaaggcgc tgaaggcagc tgctaaggac
    38521 aatctttctg acgctgttac ctcacttgga accgccattg ccatcctagc tagtagtttt
    38581 aattatccga ttgtggataa actggttgct atcatcatca ctttctttat cttgaagact
    38641 gcctatgata tcttcatcga gtcttccttt agtctttcag atggctttga cgaccgcctg
    38701 ctcgaggact accaaaaggc tatcatggaa attcccaaaa tcagcaaggt caaatcgcaa
    38761 agaggtcgca cctacggtag caacatctac ctggatatta cactagagat gaatcctgac
    38821 ttgtctgttt ttgaaagcca tgaaatcgcg gatcaggtcg agtctatgct ggaggagcgt
    38881 tttggcgtct ttgataccga tgtccatatc gaaccagcac ctatccctga ggatgaaatt
    38941 ttagacaatg tctataaaaa attgcttatg cgtgaacaat tgattgacca aggaaaccaa
    39001 ctagaagaac tcttgactga tgattttgtc tatattcgcc aagatggaga gcagatggat
    39061 aaagaggctt ataagacaaa aaaagagtta aattctgcta tcaaggacat tcaaattact
    39121 tccatcagtc aaaaaaccaa actcatctgc tatgagttag atggtatcat ccataccagt
    39181 atctggcgtc gccacgaaac ctggcaaaat atctttcatc aagaaaccaa aaaagaatag
    39241 agaaatcctt tcatgagacg ggatttttct attcttttat actcaataaa aatcaaagtg
    39301 caaattagga agccggtcac aggctgtact tgagtcggca atgtgaagcc gacatagttt
    39361 gcactttgat tttcgaatag tcttaactat caaattcact gagatactca tagcgttcgt
    39421 atttttcaag gagtgcttca tttttctcat ccaattcttt ttggagagta gccagcttac
    39481 caaagtcaga gccgttagcc tgcatttcct cttcaatagc agcgatacgt ttttccaagg
    39541 tttcaatatc accttcaata cttgcccact cctgcttttc ttggtaggtc atgcgtttct
    39601 tgtcttctcg aaccttgacc actttttcct tttcggcctt ttgcacttga ttggccatat
    39661 ctgtttcaaa agctttttca tcaagatagt cggtgtaatg accaaagaaa ggacgaatct
    39721 tgccatcctc aaaagcgaga atcttggtcg ctaccttatc caagaaatag cggtcgtgac
    39781 tgactgttaa aacgggacct gcaaaacctt gcaagaaatt ctctaagact gtcaaagttg
    39841 caatatctag gtcattggtt ggctcgtcta aaagaagaac atttggtttt tccaaaagca
    39901 gtttgaggag ataaagacgt tttttctcac cccctgacaa tttctcaatc aaagtcccat
    39961 gcgtcgaacg tgggaagagg aattgctcca gcaactcagc gatggaagtc gtagaaccac
    40021 cactggtctt gacctcctct gccacttcct gcaggtaatt gatcacacgc ttgctttcat
    40081 ccaaaccctc aatttgttga gagaaatagg cgatgcgaac agtttcccca atcacaactt
    40141 gtcctgctgt cggctcaaga cttcctgcaa tcaggttaag tagggttgat tttccaacac
    40201 cattgtcccc aacaattcca atacggtctt tagcctgaac taagagatta aaattttgca
    40261 aaatgggctt attttcatag gcaaaggaaa catcctgaaa ctcgatgact ttcttcccaa
    40321 tccgactggt ttcaaagttc atagtcaagt ctgtctcagc actactgcct gaaacttcct
    40381 ttttcagatc atggaaacga ttgatacgag cttgttgctt ggtcgcacgt gcctgcggtt
    40441 gtctgcgcat ccaggccagt tcttgtttgt agagttgttc ttttttatga agtagagctg
    40501 catcgcgctc atcctgttct gccttaaggc gaacatagtc ctggtaattg ccctgatatt
    40561 ctgtcaagcc tgctcgctcc aactcgaaaa tccgtgttga caaagcgtct aagaaataac
    40621 gatcgtgagt gataaaaagg acggtcttct tagaattttt caaaaagagg gtcagccact
    40681 caataatcgc aatatccaga tggttggtcg gctcatccaa aagcaagagg tcgtggttgc
    40741 caagtaagac ttgtgccaac tgtacccgtc ttctcagacc acctgacaat tccccaacag
    40801 gagtagataa gtcttgaatg cccaatttgc taagaacggt cttgacctga ctctcgattt
    40861 cccaagcttg gagagagtcc atctctgcca tgacacgttc caaacgcgcc tgattgtcct
    40921 cactatagtc gagcataatc aattcatact cacgaatgag ctggatttcc ttgagttcac
    40981 tagatagaac cgtatccaaa actgtctttc tatcatcaaa atcaggatcc tgagtcaagt
    41041 aaccaatctg gtaatcattt ttagctgaaa aaggactgac atccccatca aatccagaaa
    41101 caccagaaag gacgtccaaa agggtggtct tgccagtccc attgacaccg attaaaccaa
    41161 ttctgtctaa gtcatggata ataaaggaaa tatccctaaa aacggtcttg tcaccaacgg
    41221 atttacttag tttttcaacg ataaaatcac tcattttttc tccctcaggt aagcatggat
    41281 ggcttcacga ttattctcca attctccatc gacaatggca aactcaatct ctgttaaaat
    41341 ctctcccaag tctgggcctg gctgatagcc atattccttg atcaaaatac cgccattaat
    41401 ctgaatctct ttcttgtcat ggatagtcaa gctttggtat ttttctgtga tggcttgtgg
    41461 gttgacttct tttccttgag cttgacgaag attttcagcc tgtaaaagca aatctatgtc
    41521 aaagcgataa caatctcgct tgctcaattc tccattttca cgcagagcca aaataatcag
    41581 caaatcctga acttgcttgg caaactggcg tgaggtcttc caagatttca aaaatgactg
    41641 cgcattttca atctccaaag cccatagtaa agccgcccag gcttgttcag aggattcaaa
    41701 agtaaaatca gtctccaaat caaacagtct gttgagcttg tcctggctag atgccatatc
    41761 agggagatag tcataagctt gactctcaat catggaagcc aagccccttc tccaaaatgg
    41821 agccagcaag agtttatcaa actcgacgaa ggtacgctct acagaaattt tctccaaaag
    41881 cggcgtcaag gtcttcatag ctttaaatgt ttctgactca agtgcaaaac caagactagc
    41941 ctgaaaacgg aaaccacgca taatccgtaa agcatcttcg ttgaaacgct cactagccac
    42001 tccaactgct cgcaagactt gcttttccaa atcttctaaa ccatggaaca agtcaacgat
    42061 ttctcctgtc tcatccaagg caaaggcgtt gactgtgaaa tcacggcgtt tgaggtcttc
    42121 ttctagcgat cgtacaaagg aaaccgcact gggtctgcga tagtccacat agacatcctc
    42181 tgtccgaaag gttgttacct catactcctc atccccatct aagaccaaga cggttccatg
    42241 ctcgattccg atatcggctg ttcgcggaaa aatctgcttg gtctcttctg gataagaaga
    42301 cgtcgcaata tccacatcgt ggatagggct atggagaagg gcatctcgaa cagagccccc
    42361 aacaaaataa gcctcaaagc ctgcttcttt aattttttct aatactggta aagccttctg
    42421 aaattcagaa ggcatttgcg ttaatctcat aataagtgtt ctaatccata gacaagctca
    42481 tgacgcttga caacttcttt aattcccaaa ttgactcctg tcatgaagga gatgcgatca
    42541 taggagtcat gacggagggt caacccttct ccctgattgc caaagatgac ttcctgatga
    42601 gctaccaagc ctggcaaacg aactgagtgg atgcgcatac catcaaagtc agcaccacga
    42661 gcaccagcaa tcagctcttc ctcatctgct gcgccttgct gaatggactc tcgaacctct
    42721 gccattaact cagctgtttt aatggctgtt ccactcggag catccttttt cttgtcatga
    42781 tggagctcaa taatctccac atttgggaaa tatttggcag cctgcgtcgc aaattgcatg
    42841 agtaagacag cacccaaggc aaagttaggg gcaatcaggc cacccaagtc ttgggcacga
    42901 gaaaattctt ttagctctgc aatttcttca ctcgtgaaac cagtcgttcc aactactgga
    42961 gcaaagccat tttcaagagc aaaacgtgta ttttcgtagg caacagctgg agtagtaaaa
    43021 tctacccaga catccgcttc aaaaccagct aaatcagcct tatccttgaa aacaggaata
    43081 ccctgccatt ctgactcaga ctcaaaagga tccaaaactg ctaccaagtc caagtctgga
    43141 gcagtcaaga ccatctgaca agcagcctgg cccatctttc ccttaaaacc ggcaataatt
    43201 actcgaatac tcatctctac tcctgtctaa gatacaaagt ccgtaagaac acaaagtgaa
    43261 aataggaatt ccaatcaaga agtgtctact tcttggaaga actatctttt tcacacaggg
    43321 ttccaggcgt gttcaattat caagatacaa aggaccttag ctgcccctga aaaataggga
    43381 atggcactga ctttccacga aaggcaagac aggcatcttt tttcaagagg caggtagtcc
    43441 gtgttcaatt tctaagatac aaggcatctt aactagccta gaagcgccaa ctaaatcact
    43501 ggaatataac ccagagcaat acttcctgat cctaggtgcg ttccaatgac actaccaaat
    43561 gtagcaagtg aaacatccga acccaagcca aaatcaagca aatgctgacg caattcttca
    43621 gccttttcag gagcattccc atgaatgaca atgacccggt attgacctga agccgttgtt
    43681 tccttgatga tttcaattaa gcgtttggtg gccttctttt cagtacgaac tttttcgtaa
    43741 acttcaatca taccttgatc gttaaaataa aggattggct taatgctaag caaattgccc
    43801 aaaatggcag ccccatttga aaggcgtcca ccttttacca aatgatccaa gtcatctacc
    43861 atgataaagg ctgacgtacg gctgatttga atggctagct tatcctgaat gctggcaaaa
    43921 tcatcgccct gatcacgcca attaaagacg ctttcaacca tgatgcctag gggagcactt
    43981 gtaatcaaag tgtctgggaa agcaatggtt aagccctcat agtcatcgac catatactgg
    44041 atattttggt aaaaacctga aattccagaa gataggaaaa gccccaaggc atgtgtatag
    44101 ccttgttctt tgagcgaagt taagatctca tctaacttgg caatacttgg ttgactggtc
    44161 ttaggcaatt cagaagcctg agccattttt tggtaaaatt cctcagcaga cagattgatg
    44221 ccttcgacat attcctcacc atcaatattg acaggaatat ccaagacaaa caagtcttct
    44281 ctttgcaagg tctctgcact gagataagca gaggaatctg tgaaaacagc taatttcata
    44341 ttagaactcc aaattaattc ctggtaagtc taatgcaatt tcagtcactt cgtaagtcaa
    44401 acgattgagc atgttcaaac atggacgagc caaggtttcc acctcttctt ggttcaattc
    44461 acttggttca ttgacaatac ggccatcgat atggtttact tgtgagattg ttccactaat
    44521 gacaaactta tcaaatacaa tcataaagct caagatgaca atcaaggaag tcacttgatt
    44581 ttcttggtca tgttggagca attggaaatt cacatccacc ttggtttcag gagctccatt
    44641 ttcattttcc cattcaaaat tacgcgcatc aaaatgatac tgactaacaa attcttgttc
    44701 acgtttaaga ttcatgtctt tctccatcgg ctacaatatt ataagctatt gtaccataat
    44761 tttttatttt catctagttt tctaggattt agtcaatccc aatttcagca cgaactacat
    44821 ctgtgatggt atcaacatag tagtccactt cttctgttgt aggcgcttct gccataacac
    44881 gcaagagggg ctctgttcca cttggacgaa caaggatacg gccgttcccc gccatttctt
    44941 cttccatctt ctcgatgatg gccttgatag ctggcacttc catggccttt tccttcatga
    45001 cgttttccac tcggatatta actaattttt gtggataaat cgttacttct gccgccaact
    45061 ctgataagct cttaccagtt tccttcatga ttttagtcaa ttgaactgct gataattgac
    45121 catcacctgt ggtattgtaa tccatcaaga taacgtgacc agactgttca ccaccaaggt
    45181 tgtagcctga ttttctcatt tcttcaacaa cgtagcggtc accaactgca gtaactgcct
    45241 tgttaatacc ttcgcgattc aaggccttgt ggaaaccaag gttagacata acagttgtca
    45301 caattgtatt ttgagccaat tgtccttttt cagaaaggta ttttccgatg atgtacataa
    45361 tcttgtcacc atcgacgatg tcaccattct catcaacagc aatcaagcgg tcactgtctc
    45421 catcaaaggc caaaccaata gctgacccac tttctttgac cacttcttga agggcttctg
    45481 gatgtgttga accaacatta aggttgatgt taagaccgtc tggtgtttcc ccgataaccg
    45541 tcaattgggc accaaggtct gcaaagattt gacgggcact ggtagaagct gctccattag
    45601 ctgtatccaa ggcaaccttc attccatcaa gaggagttcc agttgaaaca aggtatcctt
    45661 catacttacg caagccttct ggataatcta ccaaaattcc taagccttct gcacttggac
    45721 gaggaagagt gtcttcctca gcatctagca aggcttcaat ttctgcttct ttttcatcat
    45781 ctagtttgaa gccatcaccg ccaaagaact tgattccgtt atcaagggct gggttgtggc
    45841 tagcagaaat catgacaccg gcacttgctc cttcagtttc aaccaagtaa gctactgctg
    45901 gtgttgcaag gacaccaagt ttgtatacgt gaatccctac tgaaaggaga cctgccacca
    45961 aggccgattc cagcatttcc cctgaaatac gtgtgtcacg tcctacaaag actttcagcg
    46021 cttccgtttc atgttgacta agaacatagc ctccaaaacg tcctagttta aaggctaatt
    46081 ctggtgttag ttctaggtta gcttctccac ggactccatc agtcccaaaa tatttaccca
    46141 ttgttataaa atccttttct atttttaatt cgtttttgaa ctagttgctt tcgttgacga
    46201 agatgtctcc gatgaactgc ttgtacttga atttgatgtg cttgaacttg gtgctactgg
    46261 ttttgtagtc accttcatta ttgtatcaaa cggagtgata actgccggta agacaacacc
    46321 attgcggtcg attgcctgca aaggtactga accactgtaa ttacctgtta tacgttcgct
    46381 agttggcaag acagcgataa tcttatcaat tctatccaat gtctcttggt cactcgtaat
    46441 cgacacttct ttatctgaca ccatgacatt ttcaatttgt acccgactat caatttgact
    46501 agggtcaatc tctggtacaa tctttacctt atccttctga gccttcttac caatcttgac
    46561 tgtaattttt tgcggagtcg ccacagcggt cagcccattg ggtaaatctt caatgctcaa
    46621 aggaacttca atcgttccaa caccggcatc tgttaggtca gcagtaacct tgaatttacg
    46681 tgtactttct tgcatttcac tagctagcga taggcgattt gcaccagtca agaccactga
    46741 tacttctgaa gcaaaaccgc taataaaata cttatcacta ttatagcgta tgtcaatagg
    46801 gacatttgtt actgtattag tataggtttc cgtttttacc tgcctagcac tggtactgtt
    46861 ttgaaaattc gtcgccgtag catagacaaa taagacacaa gcaaaaaaga gtgaggatat
    46921 gatatataaa ctattttttt tcatgtttcc atcctcctag ccatcgttct ttaaaactaa
    46981 gacccacttc ctcttttgga agtaagattt cacgtaattc tgtttcaaat tcatcaagtg
    47041 ttaggttgtg cttaaacctt ccattatagg ttatcgaaat tcctcccgtt tcctctgata
    47101 cgacaaaagt caaggcatct gagacttctg ataaaccgat agccgcccgg tgtctggtcc
    47161 caaattcctt ggaaatacct gtgttttttg tcaagggcag ataggcagac gtcacagcga
    47221 tacgttcttc tttgataatc accgcaccgt catgtagggg agtgttggga ataaaaatgt
    47281 taatgagaag ttctgcagaa atcttagcat ccaaggggat tcctgtcgaa atatactcct
    47341 gcaaggtacg tacacgctga atagcaacca aggccccgat tttacgagga ctcatgtatt
    47401 caacagactt aacaaaggca cgaatcatct gttcctcagc actaataggg gcattggaaa
    47461 agaaatctgt cgctcttccc aaacgttcca aaccagtccg aatctctgga gagaagataa
    47521 caaccgccgc aataacccca taagtaataa tttgattgat taaccaagaa atcgtagtca
    47581 aaccaatcat atttgcaagg atttgagcta aaataaatac caaaactcca cgtaccaaaa
    47641 tcataatctt ggttcctgca atagcttttg taaaatggta taaaatataa gcaacaatca
    47701 aaatatcaat cagattgata gctatcgtcc atggacttgc aaacaaactg gtccaatatt
    47761 gcagattgga taattgttga aaattcatcc ctgatatcct ccctatcaaa acactttcgt
    47821 cctattatac cattttcggg catttttttc cctatcctag tccattttac attgaacaaa
    47881 aatatgataa aataaactga ctagaaaaaa caaaggagaa actatgtctc aactctatga
    47941 tattaccatt gtgggtggtg gtcctgtcgg gctttttgca gccttttatg cccacctacg
    48001 ccaagccaag gttcaaatca tcgactctct tccccagcta ggtggacaac ctgctattct
    48061 ctaccctgaa aaggaaatcc tagacgtacc aggcttccca aacctgactg gagaagagtt
    48121 gactaaccgc ttgattgaac agctaaatgg atttgatacc cctattcatc tcaatgaaac
    48181 ggttcttgag attgacaaac aagaagaaga atttgccatc acaacttcta aaggaagtca
    48241 cctgactaaa acagttatca tcgctatggg tggcggtgcc ttcaaaccac gtccgctgga
    48301 acttgaaggg gttgagggct atgaaaatat ccactaccac gtttctaaca ttcagcaata
    48361 cgctggtaag aaagtgacga ttcttggtgg gggagactcg gctgtggatt gggctttggc
    48421 ttttgaaaaa atcgcaccaa ctacccttgt tcaccgcaga gataatttcc gtgccttgga
    48481 acacagtgtt caagccttgc aagaatcatc tgtaaccatc aagacaccat tcgcccctgg
    48541 ccaactcctt ggaaatggaa aaacacttga taaacttgaa atcacaaaag tcaaatctga
    48601 tgaaactgaa accattgacc tagaccacct ctttgtcaac tatggtttca aatcttctgt
    48661 cggtaacctt aaaaactggg ggctcgacct caaccgtcac aagattatcg tcaacagcaa
    48721 acaagaatcc agccaagcag gtatctatgc tatcggtgac tgctgctact atgacggaaa
    48781 aattgatctg attgcgacag gcctcggaga agctccaact gctgtcaaca acgctatcaa
    48841 ctacattgac cctgaacaaa aagtacaacc aaaacactct accagtttat aaaaaagaac
    48901 cacgagtcac ataggattcg tggttttata attcatccgc tatcttattg atttttctga
    48961 gtctgtgatt gacaccactt ttggtcagag gggtgctgag actatctgct aactgctgga
    49021 tagagtagtc tgggtgctga atcctcagtt gcgccacttc ctgcaaatct actggcaaat
    49081 tttctaagcc catgatatct ttgattttac tgatattgtt aatggtcttc atgctggcag
    49141 aaactgtccg agcgatatta gctgtctcgg cattattagc ccgattgagg tcgttacggg
    49201 tttctcgcaa aatcttaacc cgctcaaaat catcacgtgc ctgcatggct ccgattacta
    49261 tcaagaagtc cataatgtct tctgctcgct ggagataggt cacagccccc ttcttgcgct
    49321 caagcacctt ggcatccagt aaaaactgtt ggagaaggga ggcaattcct tgcgcgtggt
    49381 ccagataaac agaactgatt tccaactggt acttgcctga ctcagggtca cgaatgctcc
    49441 catttgccaa gaaagcgcca cagagatagg cacgacctgc ttcctcatcc gataaaatcg
    49501 cctcatcaat acctgtttcc aggccaaaga aagagtctgc caagtgcaaa tcacttaaca
    49561 aatcctgcac cttttcatct gtaaaaacgg tatagacgcg attcttgcga agattgctac
    49621 gttggtggtg acgaatttca gatttgattt catagaaatg aagaaaggac tcatagaggt
    49681 gacgggccag tttggcattt tctgtcacaa ctgacaaagt caagcccgaa gtcgagagac
    49741 cgatgctacc agacattttg ataatggcag ataattcatg ccagctcaga tggtgttggc
    49801 ccaggatttc ttcttttact gctactgtga aactcatttt ttcacctgta taatgcgcat
    49861 caactcgtcc acaatcaaat ctccatcgtg gaaggcaccg ccattttcca gacgaaggaa
    49921 gttagatgaa atcacgcgtg aaacttgctt acaaagacct acaaaatcgt gttccacttg
    49981 cactaagtat tcatcaaaac ggttggaatt catgtattcc tgaggcactt tttcaatatt
    50041 caccaagaca gtgtcgataa aagggcgacc aaggtgacga tgcaagactt ccacgtggtc
    50101 gctatctgta aagtgttccg tctccccacg ttgggtcatg atattgcaga cataggcaat
    50161 ttctgccttg gtttccaaaa gagcccgccc aatttcctta atcacgatat tgggcaaaat
    50221 agaggtaaag agggaacctg gccctaggac aatcatgtca ctttcaagga tggtctgcac
    50281 tactcgacgg ctggccagag gcgtatcatc gtttagggca ttggtcacat agacattgtc
    50341 aattatgcct cgatggtcta caatatgact ctctccagcc acttctatcc catcctgaaa
    50401 gactgcatga agggtcaaag gatggtcact ggaaggataa attttccctg ttgtatggaa
    50461 aaatttgctc aataactgca tggcattata ggttgaaccc tgcatttctg acaagccagc
    50521 aatgatgaga tttcccaatg gatggccagc aaaggctccg gcatcctcag agaaccgata
    50581 ctgaaagacc ttctcataaa acttaggcat atccgacatg gccacaagga cattacgaag
    50641 atcacctggc ggtgtcaact gttgcatatt ttttcggagt tcacctgaag aaccaccatc
    50701 atctgccacc gtcacgatag ctgcgatttc cacatctttt tcccgcagac tttttagaat
    50761 gacgggaatt ccagtccctc caccaatcac cgttatcttt ggttttctca tgaacggttt
    50821 accgtttcct ttctgcggtc tttgtcgcga tgcccttcat taacagacca attcttggat
    50881 aagtcctgca ccaagcgttt agcaaatgcc acactacggt gttgtccacc cgtacatccc
    50941 atggcaatgg tcaaaacgga cttaccttcc ttttggtaac ttggcagaat cggctcaatc
    51001 aaggccaata aatgttgata aaagtcttct gactcaggat ggttcatgac ataatcataa
    51061 acaggttcat ccacacccgt ttggtttctc agttctagta aataataggg atttggcaag
    51121 aaacggacat caaagaccaa gtccgcatca atcgggattc catacttaaa tccgaaagac
    51181 atgacttcga tacggaaaga ctgggcttgt tcttggtctg aaaactgctc tgcaagggtt
    51241 ttgcgcagct cacgtggagt gagttcagtc gtatccacca cattttggct catatttttc
    51301 aaaggtgcca agagttcacg ttccaacttg attccatcta aaatacgacc gtctgctgct
    51361 agtgggtgac tccgtctggt ttccttgtaa cgagcgacca attccttatc agccgcatcc
    51421 aaaaagagga ttttgaaatc caaaccatct tgattttcca actcatccaa aacagcttga
    51481 atctctgaaa agaaagaacg gctacgcata tccactacca aggccaactt aggattgtct
    51541 tccttaattt caaccagctg caaaaactta ggcaagagag ctggcggcat attatcaatg
    51601 gtgaaataac ctagatcctc gaaggactga atggctacag ttttccctgc gccactcatc
    51661 cctgtcacaa tcaccaagtg aagttgtttc tttgtcatct ttttctcctt atatcaaaag
    51721 aagtttggca acaccaaact tcaactagct tatccaatct ctgcgatgac ttcaatttcg
    51781 acttttacat cacgaggaag acgagctacc tccacagctg aacgagctgg gaattcctct
    51841 ttgaaggccg tttggtaaac ctcattaaaa ggaacaaagt cgttcatatc gctcaagaaa
    51901 caagttgttt tgacaacatg gtcaaagtct gttcctgctt ctgccaaaat agcaccgatg
    51961 tttttcaaga cttgctctgt ctgttcttgg atattctctc ctacaatttc cccagtttca
    52021 ggggataggg gaacttgacc gctagcaaac aaaaggttgc caacgatttt tccttgaaca
    52081 tagggcccga tagcctttgg ggccttatct gtatgaattg tttttgccat tttcttttcc
    52141 tcacaatttt tctaagattg catcccaagc ctcatccatc cctgccttgc tgacagatga
    52201 aaagaggatg aaatcgtcac ttgggtcaaa gtttaatttc tttttgattg ctgattcatg
    52261 cttgttccat ttaccacgag gaatcttgtc cgccttggtc gccacaatga tgactggaat
    52321 ctcataatac ttgagaaatt cgtacatctg cacatcatct gctgacgggt catgacgaag
    52381 gtcaactaga ctgacaaccg cacggagatt ttcccgagtc gttaagtact cctcaatcat
    52441 gcacccccac ttttcacgtt cctttttaga aacacgagca tagccataac caggcacatc
    52501 cacaaagcgc atcttgtcat caatgttaaa aaagttcagg agctgggttt taccaggttt
    52561 tcctgatgta cgagcgagat tcttacggtt caacatagtg ttgataaagc tggatttacc
    52621 aacatttgaa cgccctgcta gggcaatctc tggcagttca tcctgcggat agtgggactt
    52681 attagctgca ctgagcaaga tttcagcatt gtgtgtatta agttccatag tcacctctag
    52741 gctgtttcta ggatcggttt atccgttcca tcgacagttt ctttagtgat gcgaaccaat
    52801 ttcacatttt cctgactcgg cacctcaaac ataacatcta gcatggtttc ttcgatgatg
    52861 gagcgaagtc cacgcgcccc tgtcttccgt tcgattgctt tattagcaat ctcttgaagg
    52921 gcttcgtcgt caaattccaa ctcaacatca tcataagaaa gcaaggtttg gtattgtttc
    52981 accaaggcat ttcttggctc tttcaagatg cgaaccaagt catcaacggt caattgctca
    53041 agagccgcaa aaacaggcaa gcgtccaatc aactcaggga taataccaaa tttttgaatg
    53101 tcttcagcga tgatttcttg catgtatgag ctgttttcgt caatcgcctt attgttttga
    53161 ccaaatccga tgactttttc acccagacgt tgtttgacaa tttcttcaat accatcaaaa
    53221 gcaccaccca cgatgaagag gatatttttt gtatccactt gaatcatctc ttgttgtgga
    53281 tgtttgcgtc caccttgagg cggtacgcta gcaacagttc cctcaataat cttgagaagg
    53341 gcttgttgca ccccttcacc agaaacatca cgtgtgatag acacattctc actcttcttg
    53401 gcaatcttgt caatttcatc cacatagata atgccacgct ctgcacgttc gatgttaaag
    53461 tcagcaacct gcaagagttt gaggagtata ttttccacat cctcacccac ataaccagcc
    53521 tccgtcagag ctgtcgcatc cgcaatagca aaaggtacat tcaagctctt agccaaggtc
    53581 tgggcaagga aagttttccc tgaaccagtt gggccaatca tcaaaatgtt tgacttctgc
    53641 aaatccacat cttctgactc ttcgcgtgta tcgtggaaat tgatgcgttt gtagtggtta
    53701 taaaccgcca ctgccaaggc acgcttggca cgatcttgac caattacata gtggttcaag
    53761 atatggagga gttcaattgg ttttggcacc tcagacaagt ctgccaagac ttcctcaacc
    53821 aattcttctc gaatgatttc ctgagctaac tccacgcatt cattacaaat aaaagcattg
    53881 ttgccagcaa ttattttttg tacttcttct tggtttttgc cacaaaatga gcaataaacc
    53941 atcatatcat tttttctatt tgtagacatg atttccttcc attctatact gtcattctat
    54001 ctaaaataag gtcatgtaaa aagcatgaat actattgacc agattggtaa aggcatttaa
    54061 ccaaaggagg atagaaagcc cgtaacgctt tttacgaaaa gcttgtgctc ctgccagaaa
    54121 gcagatgaaa cacagaaaag ccgtgaatag accaaataaa ctccgttcca ttaaacttcc
    54181 tttctcttgc ggtattggat ggtaaaatca taaggattct tctcatcttt ggcgtaaaat
    54241 ttgcttgaaa ctgtctcaaa aagagacaag tcaagctctt cagggaaata ggtatctcct
    54301 tccacccgag catgaatgtg agtgacaatc acttcatcaa ggtaagcttc aaaagcctga
    54361 aaaatttgct tcccaccgat aatgtagaga ttcttttctt gagcctgata ccagtcaaga
    54421 acagactgga cgtcctgaaa agtagcaacc ccatctatct tttcttccgg attacgcgtc
    54481 aaaatcaagg tttcccgttt tggaagcaag cgacgcccca tcccatcaaa ggtcacacgc
    54541 cccatcaaga tagcatgatt cagagttgtt tctttaaagt gctgcaattc tgctggcaaa
    54601 tgccaaggca gacgattttc cttaccaatc acaccctctt catcctgggc ccaaatagct
    54661 acgattttct tagtcatgct tccatccttt tcactgatag tactatttta tcaaaaaact
    54721 caaaaaaaga ctggtttgga atagcttaca aaatagaaaa aatctgtaag aaatttccta
    54781 cagatttatc tatgtttcct tatttcttac aaaccaggtg cttgtccaag ttcggctgca
    54841 agcatccaaa ttgttttatc tgtttcagtt ttagcgcctg caaagatacc gtttgttaca
    54901 tcgtcacctt cttcatcagt gacatccaaa cctttttgga aaagttctga caagtaacgg
    54961 tagataacaa gaacacgttc caagctttct tcaacattac ggtattcacc agcttcttct
    55021 tcgatttcac tattttgaag gaactctgtc aatgtagaga atgggcttcc accgagtgta
    55081 atcaagcgtt cgctgatttc atccaattga ccgtcaagag cttccatgta ctcatccatt
    55141 tttggatgcc atacaaggaa accacgacca tgcatatacc agtgcacttg gtgcaaagca
    55201 acgtgagcta catacaaatc agcaacagct tggttcaaga cttcctttgt ttttgccaat
    55261 gctactggcg ctgcttttgt caatgatgtt acgtctttta ctgcttcttt tttcaattct
    55321 accattttct ttacctcatt cattattttt tgtaaccact tcttaatgat tactacctta
    55381 gtatactact aaggaaaacc aatagcaaga caaagaactt atatgagaaa agttgcaata
    55441 gactgataat ttaagaattc tttagaagac aaaaagaggg ttggatgctt atagtcaatg
    55501 gaaatccatc agcaaactag gaaactaaac ccagcttgac caaagcacaa gttttgaggt
    55561 cgcaggtaga actgaccaag ctgatgtggt ttgaagaaat tccccaatac tataatagat
    55621 tgaaataaga tgaaaccaag tcgattagga aaggtaaatg aatttctaaa atgttttacc
    55681 aatcacaagg tctttgtcta tattcaatct actatataag cttcatttcc gagcaagatc
    55741 ttgaatttac tcgaggatga actatcataa aacaaagaaa aagagggtgc tactatcaca
    55801 tccctctttc aaatcatcgc ttaataccaa acgctgacat ctacgcgccc ttggattcct
    55861 ttcatgtatt cagaagaggt atattgccaa cctttttctc ctgaataata agggttttcc
    55921 cattctaaag cattcgtata ggccgctacc cagtttacat gttttaaaat atctgggtgt
    55981 tttaaacgcg tctgtaataa actacgatag ctatagacat acacattttg ataacccgcc
    56041 tgcttcatcg tgtccatgta cttgttgatg attttaaccc aagtgcctgt atcacttgga
    56101 gctctcttgc tcttatttac atattcccag ttctcaacat cataatagat agggtaagac
    56161 aggttcatat tgtatttctt tataagttca atggtctgtt tagcgtcatt ctcagcatcg
    56221 gtctcatttt cagcataggt atagagatag acaccataag gaattcccag acggtttaac
    56281 tccttaatgt tatgcgccaa ttccttgtct tctttaccgc tataacctag acgaacaatg
    56341 acaccatcca cctcgttctc atcaataacc tttttccaat cattgatacg accattgtgc
    56401 tcactaatat caatgacttt cttagcatgt tcggttccca cttgttcttc tctattatta
    56461 aagaaatagc gtttaccatc tctgtgaacc cagccgacat tcaaatcttt cttttctttg
    56521 agctcaccag aggccgcaaa gatatagcga gcaccatcca taatcacttc gtcagttgct
    56581 atggcaccac ttccagtcaa atagtagttg ccttgccact cattccgagc catatagccc
    56641 cacttcttga agtagtacca cttatttcca atcaattgcc attcttgatg agcataagcc
    56701 ccatctgact tgagataaaa ccaactcttg taattactgt catagattca ctcgttttgg
    56761 gccatatatc cacctgattt caggtagtaa tttccatgcc attcattctg cgagtaacga
    56821 ccatctgaat taatataaaa ccaaacctta tagtagttgt caaaaatcca ttcactttga
    56881 gctttagaac catcatcctt tacataataa tccccatccc agtgggcagc agcattagtc
    56941 tgtacttctg cgctcgtttg cgttttatta gaagactgat tttgctttga actacttgaa
    57001 gctgtcgttg tatcctgcga agtttttgct acttcagttt catttgcagc gacatgacta
    57061 gttgccaagc ctagtaaaca gatacttgct aatccaattt ttgttttcaa tctttcctct
    57121 cctataaaaa atgtaacaga catctgaatg ctgttccacc tagcttttgc tacttactga
    57181 ttattttaca aagtcaagca aagccaagaa gctttcagct tcaagtgacg caccacctac
    57241 aagggcaccg tcaacgtctg ggcaagccat gtatgaagca acattttcag gtttaacaga
    57301 accaccgtat tgaacacgaa ctttgtctgc gacttcttga ccaaagtcag cagctacaac
    57361 gtcacgaaca actttacaca ttttttgtgc atcgtcttgt gaagctgatt taccagtacc
    57421 gatagcccag attggctcat aagcgataac tgaggcagca acttgttcag cagtcaatcc
    57481 agccaatgca gcagatactt gagcacctac gaattcagca gctttaccag cttcgtaagt
    57541 ttcaagtgat tcaccacaac agatgattgg aagcataccg ttcgcaaaga ttgcttttgc
    57601 ttttttgttg atatcttcgt cagtttcatg gaagtagtca cggcgttctg agtgaccgat
    57661 aacaacgtag tcagtaccga tttctttcaa aacttgtggg ctagtttcac cagtgaaagc
    57721 acctgcattt tcaaagtagc agttttgagc agcaacttta aagtttgagc cttttgcaac
    57781 agcaagaaca gttgtcaaat caagagctgg agcagcgata cctgcttcaa caagatctga
    57841 tgaaggaagt tttgatgcaa ctgcttcaac gaatgcttta gcttcttctg gatttttgtt
    57901 cattttccag ttaccagcga taaatggttt acgtgacatt tcacatacct ctttttcaat
    57961 ttattttcta tttattctat cacaattata cacagcttgc aaatcttact cggatttcaa
    58021 gcctgcttgc atggattaat ccttccagag atccatggca tttctgaaat ctgcagatac
    58081 ctgtgtcaac tgaggattgc ttgcttctct ttctgctctc ttggcctcaa tttgagccac
    58141 actcttgatt ccttcatggc gccagtttct caaaatcgcc tgaatgtact tccagtttgg
    58201 ttttccattc aaaacagctt cacgaagagc ctccttaatc aagtcagcac tggttccatc
    58261 ttcctttagt gtcttggtca aatcctcaat ctcaaaaggc gtcaacaatc gtcccaactc
    58321 ctgctggaag gtttccacca aatccttgag ctggttttga ggtgttagct ggtctgaact
    58381 tgaatgaact gctccaaaca ggtcatccaa acgttccaag gccaaactag catcaaagag
    58441 caattcaatt tcgccattta attcgatagt acgatactgg agcagtcccc tttccgtcag
    58501 attagaaatg gactggttga catccgaaat ttccttgcca atcctttcag caatctggct
    58561 tggcgacatt tcttctaagc ctgtcgtatt ttgcaaatag aaaaattgcc aaaccagaaa
    58621 atcgtcgcta gaaggaaaga gttccttaaa atgcaagagc agggcactcg gtaaaaccaa
    58681 ggtacctgat ttaaaagcgt ctaaatatgt cataattcct cttataaata cccatatgca
    58741 gatgcatcat cttctatctt tatccaatca aaaggcgtct cctgatagac cgcatggttt
    58801 acccaattac tgaaaaagag ggctgcagat gaagaccaac aaagacaagg tacctgatta
    58861 acatcatcat ctttaaagta attttctgga atatgtgggt cgaaacctgc atcacgatct
    58921 cgaaaatact cttttgccaa ggtatcacgg tcatactcca aatgaccaaa actataaatt
    58981 tctcgtaaat cacgactggc caaaatagaa accccaacct gaggtccttc tgataaaatc
    59041 tcgagattgg tcttgtttaa gacctcttcc ttagaaatct ccgtgtgccg tgaatgaggg
    59101 gatacatagc tatcatcaaa gcctctaaat agaaggtgac cctcttttag ggtgtcctga
    59161 ggataaatac ctgatagctt actgtccatc tggtattttt ctacaccata gcgcagataa
    59221 agcccagcct gagcccccca acagatatga agggtcgaat agacatgagt cttagaccac
    59281 tcaagcatct gtctaaattc ctcccaatag tccacttcct caaatggtaa atgctcaact
    59341 ggagcacccg tgatgatcat cccatcaaaa tactcatcct tgacttcagg aaaagtttta
    59401 tagaaggtct ccatgtgctc tgaacgagtt gttttagaac ggtggctctc catatagaga
    59461 aaatcaatat ccagttgtag gggtgtatta gccaagtggc gcaacaactg ggtctctgtg
    59521 accattttct gtggcatgag atttaaaatt aaaatcttca aaggacggat atcttggtgg
    59581 gcagcacgtt gatcatccat gacaaagata ttctctgtcc gtaaaatctc aacagctggc
    59641 aattttttat caattcgaat cggcataacc ctctcctaac tgtactcttt caggaataat
    59701 tgcatatgtt tgaagacaaa tctcaaacac ttagtccttt tattatactg taagaagata
    59761 tagttttcaa ttatagtttt tctctaacta gttatagtct atttttatat cctagtgtag
    59821 agaaaacagc cctagggact gttttcatta at
//
LOCUS       DAVKMO010000007        56772 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVKMO010000007 DAVKMO010000000
VERSION     DAVKMO010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56772
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.007"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            42..157
                     /gene="rrf"
                     /locus_tag="VW361_000487"
     rRNA            42..157
                     /gene="rrf"
                     /locus_tag="VW361_000487"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            162..234
                     /locus_tag="VW361_000488"
     tRNA            162..234
                     /locus_tag="VW361_000488"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:195..197,aa:Val,seq:tac)
     gene            240..310
                     /locus_tag="VW361_000489"
     tRNA            240..310
                     /locus_tag="VW361_000489"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:272..274,aa:Gly,seq:tcc)
     gene            345..418
                     /locus_tag="VW361_000490"
     tRNA            345..418
                     /locus_tag="VW361_000490"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:379..381,aa:Ile,seq:gat)
     gene            501..590
                     /locus_tag="VW361_000491"
     tRNA            501..590
                     /locus_tag="VW361_000491"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:537..539,aa:Ser,seq:tga)
     gene            601..674
                     /locus_tag="VW361_000492"
     tRNA            601..674
                     /locus_tag="VW361_000492"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:635..637,aa:Met,seq:cat)
     gene            678..750
                     /locus_tag="VW361_000493"
     tRNA            678..750
                     /locus_tag="VW361_000493"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:711..713,aa:Phe,seq:gaa)
     gene            763..843
                     /locus_tag="VW361_000494"
     tRNA            763..843
                     /locus_tag="VW361_000494"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:797..799,aa:Tyr,seq:gta)
     gene            848..918
                     /locus_tag="VW361_000495"
     tRNA            848..918
                     /locus_tag="VW361_000495"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:880..882,aa:Trp,seq:cca)
     gene            933..1005
                     /locus_tag="VW361_000496"
     tRNA            933..1005
                     /locus_tag="VW361_000496"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:966..968,aa:His,seq:gtg)
     gene            1019..1090
                     /locus_tag="VW361_000497"
     tRNA            1019..1090
                     /locus_tag="VW361_000497"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:Gln,seq:ttg)
     gene            1100..1183
                     /locus_tag="VW361_000498"
     tRNA            1100..1183
                     /locus_tag="VW361_000498"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1134..1136,aa:Leu,seq:caa)
     gene            1290..2567
                     /locus_tag="VW361_000499"
     CDS             1290..2567
                     /locus_tag="VW361_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU9743609.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2643..4127
                     /locus_tag="VW361_000500"
     CDS             2643..4127
                     /locus_tag="VW361_000500"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU9743610.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALRERLAA
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNDAVKTAELMNTLNTQGQYELTDFDVEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQVAVEAYLGL"
     gene            4188..5468
                     /locus_tag="VW361_000501"
     CDS             4188..5468
                     /locus_tag="VW361_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9743611.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMILKG"
     gene            5472..6095
                     /locus_tag="VW361_000502"
     CDS             5472..6095
                     /locus_tag="VW361_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9743612.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQDLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFEAER"
     gene            6257..7399
                     /locus_tag="VW361_000503"
     CDS             6257..7399
                     /locus_tag="VW361_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9743613.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAEKQETQASPQAALAVEATTTS
                     SEAKEVASSNGATAAVSTYQSEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7722..8147
                     /locus_tag="VW361_000504"
     CDS             7722..8147
                     /locus_tag="VW361_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU9743614.1"
                     /translation="MLEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIRVKEEIESILTEFERTELSRLLNKLVLGIENIEI"
     gene            8158..8517
                     /locus_tag="VW361_000505"
     CDS             8158..8517
                     /locus_tag="VW361_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HEU9743615.1"
                     /translation="MSIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELAHPS
                     VSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKIILKQ
                     GGSAILALISILLFKYT"
     gene            8624..9241
                     /locus_tag="VW361_000506"
                     /pseudo
     CDS             8624..9241
                     /locus_tag="VW361_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9268..10125)
                     /locus_tag="VW361_000507"
     CDS             complement(9268..10125)
                     /locus_tag="VW361_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU9743616.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCHSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10255..11397
                     /gene="tgt"
                     /locus_tag="VW361_000508"
     CDS             10255..11397
                     /gene="tgt"
                     /locus_tag="VW361_000508"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU9743617.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11498..13315
                     /locus_tag="VW361_000509"
     CDS             11498..13315
                     /locus_tag="VW361_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU9743618.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPIVQTLRPLPYIHAILAAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13468..14619
                     /gene="nagA"
                     /locus_tag="VW361_000510"
     CDS             13468..14619
                     /gene="nagA"
                     /locus_tag="VW361_000510"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU9743619.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14782..15840
                     /locus_tag="VW361_000511"
     CDS             14782..15840
                     /locus_tag="VW361_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU9743620.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTLDDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15991..16356
                     /locus_tag="VW361_000512"
     CDS             15991..16356
                     /locus_tag="VW361_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU9743621.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16432..17373
                     /locus_tag="VW361_000513"
     CDS             16432..17373
                     /locus_tag="VW361_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU9743622.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDIETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17321..18337
                     /locus_tag="VW361_000514"
     CDS             17321..18337
                     /locus_tag="VW361_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU9743623.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18339..18665
                     /gene="comGC"
                     /locus_tag="VW361_000515"
     CDS             18339..18665
                     /gene="comGC"
                     /locus_tag="VW361_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU9743624.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKEDGRITEEQAKAYKEYNDKNVGA
                     NRKVND"
     gene            18658..19062
                     /locus_tag="VW361_000516"
     CDS             18658..19062
                     /locus_tag="VW361_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU9743625.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTNLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            19067..19327
                     /locus_tag="VW361_000517"
     CDS             19067..19327
                     /locus_tag="VW361_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743626.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19290..19751
                     /locus_tag="VW361_000518"
     CDS             19290..19751
                     /locus_tag="VW361_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9743627.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            19729..20142
                     /locus_tag="VW361_000519"
     CDS             19729..20142
                     /locus_tag="VW361_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9743628.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKVEQESGEQVFNLGQVSYQNKKTGLVTRVRTDKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20279..20873
                     /locus_tag="VW361_000520"
                     /pseudo
     CDS             20279..20873
                     /locus_tag="VW361_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20934..21887
                     /locus_tag="VW361_000521"
     CDS             20934..21887
                     /locus_tag="VW361_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9743629.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELEQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21938..23128
                     /locus_tag="VW361_000522"
     CDS             21938..23128
                     /locus_tag="VW361_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU9743630.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23277..23648
                     /gene="rnpA"
                     /locus_tag="VW361_000523"
     CDS             23277..23648
                     /gene="rnpA"
                     /locus_tag="VW361_000523"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU9743631.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYQEGNGSEKETKVD"
     gene            23623..24447
                     /locus_tag="VW361_000524"
     CDS             23623..24447
                     /locus_tag="VW361_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9743632.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNEVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGQFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24466..25452
                     /locus_tag="VW361_000525"
     CDS             24466..25452
                     /locus_tag="VW361_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU9743633.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25503..26126
                     /locus_tag="VW361_000526"
     CDS             25503..26126
                     /locus_tag="VW361_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU9743634.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26257..27714
                     /locus_tag="VW361_000527"
     CDS             26257..27714
                     /locus_tag="VW361_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9743635.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27737..28018
                     /locus_tag="VW361_000528"
     CDS             27737..28018
                     /locus_tag="VW361_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9743636.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            28095..28580
                     /locus_tag="VW361_000529"
     CDS             28095..28580
                     /locus_tag="VW361_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9743637.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELDDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28597..29262
                     /locus_tag="VW361_000530"
     CDS             28597..29262
                     /locus_tag="VW361_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU9743638.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIRR
                     IWG"
     gene            29266..30129
                     /locus_tag="VW361_000531"
     CDS             29266..30129
                     /locus_tag="VW361_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU9743639.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIATLHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            30131..30835
                     /locus_tag="VW361_000532"
     CDS             30131..30835
                     /locus_tag="VW361_000532"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU9743640.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDFPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            31012..32685
                     /locus_tag="VW361_000533"
     CDS             31012..32685
                     /locus_tag="VW361_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9743641.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTLSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNESKSFSENLSSLISSYIVDSKLASKFQEEVQTFINQEIVVQAFLEDI"
     gene            32797..33888
                     /gene="ulaG"
                     /locus_tag="VW361_000534"
     CDS             32797..33888
                     /gene="ulaG"
                     /locus_tag="VW361_000534"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU9743642.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            34002..35984
                     /gene="tkt"
                     /locus_tag="VW361_000535"
     CDS             34002..35984
                     /gene="tkt"
                     /locus_tag="VW361_000535"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9743643.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVAAAKEL
                     ASKGEKVRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLKQS"
     gene            36095..36394
                     /gene="yajC"
                     /locus_tag="VW361_000536"
     CDS             36095..36394
                     /gene="yajC"
                     /locus_tag="VW361_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9743644.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36441..36869
                     /locus_tag="VW361_000537"
     CDS             36441..36869
                     /locus_tag="VW361_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU9743645.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNVSDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36871..37281
                     /locus_tag="VW361_000538"
     CDS             36871..37281
                     /locus_tag="VW361_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743646.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37580..40231
                     /gene="adhE"
                     /locus_tag="VW361_000539"
                     /gene_synonym="adhC"
     CDS             37580..40231
                     /gene="adhE"
                     /locus_tag="VW361_000539"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU9743647.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(41098..41406)
                     /locus_tag="VW361_000540"
     CDS             complement(41098..41406)
                     /locus_tag="VW361_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9743648.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(41403..41711)
                     /locus_tag="VW361_000541"
     CDS             complement(41403..41711)
                     /locus_tag="VW361_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9743649.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALEWIGEIR
                     "
     gene            complement(41716..43011)
                     /locus_tag="VW361_000542"
     CDS             complement(41716..43011)
                     /locus_tag="VW361_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9743650.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(43029..44438)
                     /locus_tag="VW361_000543"
     CDS             complement(43029..44438)
                     /locus_tag="VW361_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9743651.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTALTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            44596..45324
                     /locus_tag="VW361_000544"
     CDS             44596..45324
                     /locus_tag="VW361_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9743652.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            45784..45978
                     /locus_tag="VW361_000545"
     CDS             45784..45978
                     /locus_tag="VW361_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9743653.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(46344..47654)
                     /locus_tag="VW361_000546"
     CDS             complement(46344..47654)
                     /locus_tag="VW361_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU9743654.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            47891..48763
                     /locus_tag="VW361_000547"
     CDS             47891..48763
                     /locus_tag="VW361_000547"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU9743655.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQRAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            48894..49740
                     /locus_tag="VW361_000548"
                     /pseudo
     CDS             48894..49740
                     /locus_tag="VW361_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            49943..50776
                     /locus_tag="VW361_000549"
                     /pseudo
     CDS             49943..50776
                     /locus_tag="VW361_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857688.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            50953..51960
                     /gene="gap"
                     /locus_tag="VW361_000550"
     CDS             50953..51960
                     /gene="gap"
                     /locus_tag="VW361_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU9743656.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(52028..52864)
                     /locus_tag="VW361_000551"
     CDS             complement(52028..52864)
                     /locus_tag="VW361_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9743657.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            52990..55185
                     /locus_tag="VW361_000552"
     CDS             52990..55185
                     /locus_tag="VW361_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9743658.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            55238..55390
                     /gene="rpmG"
                     /locus_tag="VW361_000553"
     CDS             55238..55390
                     /gene="rpmG"
                     /locus_tag="VW361_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9743659.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            55400..55576
                     /gene="secE"
                     /locus_tag="VW361_000554"
     CDS             55400..55576
                     /gene="secE"
                     /locus_tag="VW361_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU9743660.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            55631..56167
                     /gene="nusG"
                     /locus_tag="VW361_000555"
     CDS             55631..56167
                     /gene="nusG"
                     /locus_tag="VW361_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU9743661.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
     gene            56289..56768
                     /locus_tag="VW361_000556"
     CDS             56289..56768
                     /locus_tag="VW361_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU9743662.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRKYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT        17380 a        10108 c        12436 g        16848 t
ORIGIN      
        1 agttgaatag atattcaatt ttgagtaggt attactcaga gttaagtgac gatagcctag
       61 gagatacacc tgtacccatg ccgaacacag aagttaagcc ctagaacgcc ggaagtagtt
      121 gggggttgcc ccctgtgaga tagggaagtc gcttagctct agggagttta gctcagctgg
      181 gagagcatct gccttacaag cagagggtca gcggttcgat cccgttaact cccattttag
      241 cgggtgtagt ttagtggtaa aactacagcc ttccaagctg ttgtcgcgag ttcgattctc
      301 gtcacccgct ttgaactttg ttctttgtac caagttttta acttgggcgc gtagctcagg
      361 tggttagagc gcacgcctga taagcgtgag gtcggtggtt cgagtccact cgtgcccata
      421 gtgtttagtc cattactagg ggattggaat attatctgtt cactaagagg acacgggctt
      481 gttcccgtat aaactatttt ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
      541 aaccgtcagg cgtgtaaaag cgtgcgtggg ttcgaatccc acatcctcct tttatattaa
      601 cgcgggatgg agcagcacgg tagctcgtcg ggctcataac ccgaaggtcg taggttcaaa
      661 tcctgctccc gcaataaggc tcggtagctc agttggtaga gcaatggatt gaagctccat
      721 gtgtcggcgg ttcgattccg tctcgcgcca tttatatatt ttggaagggt agcgaagagg
      781 ctaaacgcgg cggactgtaa atccgctcct tcgggttcgg gggttcgaat ccctcccctt
      841 ccattttacg ggcatagttt aaaggtagaa ctaaggtctc caaaaccttc agtgtgggtt
      901 caattcctac tgcccgtgtt aatagaatta tggcgggtgt ggtgaagtgg ttaacacacc
      961 agattgtggc tctggcatgc gtgggttcga tccccatcac tcgcctattt tatattattg
     1021 gggtatagcc aagcggtaag gcaagggact ttgactccct catgcgttgg ttcgaatcca
     1081 gctaccccag ttactatttg ccggcgtggc ggaattggca gacgcgctgg actcaaaatc
     1141 cagtgtccgc aaggacgtgc cggttcgacc ccggccgccg gtatagtata gtgttaggaa
     1201 cgttgttatt cttcgttcct tttttatatt atttttggta taattatagt tattcaaatt
     1261 ttatttagat tgagaaagtg tagggtagta tgtcttgttc tatcgattta ttaaaacatc
     1321 ggtatttgaa aaatattaaa gaaaatcctg aattgtttgt cggaattgag ttggagtatc
     1381 ctgttgcaag tttagaaggg gatgctacag atgttgaagt tataaaggat ctatttcatt
     1441 atttagtttc tactttggat ctcaccgtag caaaggtaga tgattttggc aatctgattc
     1501 agttagtaga tccgataagt caggatgcta ttttgtttga agtttcctat acaacgattg
     1561 agtttgcatt tggtaaggct gaaacgattc aagaggtcga aaatcgtttc aataattata
     1621 tgaatgtaat tcagagaaag ttagctgaat caaatcatgc tattgttggc tgtggtatcc
     1681 atcccaactg ggataaaaat gagaattgtc cagtggctta tccacgctat cagatgttga
     1741 tggattattt gaatttgagt agaaatatta ttaaatcaga tttacatcat ttccctgaat
     1801 atggtacttt tatctgtggg agccaggttc agctggatat ttcaaaaact aactacttac
     1861 gggtgattaa tgcttttact caaattgaag cggctaaggc ttatttattt gcaaactctg
     1921 agttttcggg tgcggattgg gatacgaaaa tttcaaggga tattttctgg gaagaatcta
     1981 tgcatggtat ctatccagag aatgttgggg tcaatgctag actccttaat gatgaagctg
     2041 atttttttga ctatctaaat cattctgcga tttttactgc ggaacgtgat gggcagacct
     2101 attattttta tcctattcag gctggggact atttggctac gcctgaaatc caagcatttg
     2161 ctctgaatgg ggatgaggtt attatttacc cccaagagaa ggattttgaa actcatcgta
     2221 gttaccagta ccaagactta acgactcgag gaacagttga gtttcgtagt gtgtgtacac
     2281 agccacttga taggactttt gcttctgcag cttttcactt gggattattg gttaatttag
     2341 acaagttaga agcttactta gaaacagcac ctttctttaa agtatttggt tatgattaca
     2401 agtttttaag gagacaattt tctaagaaaa atcttacaga tgaggaagaa actacgatta
     2461 ttgaattttc caaagactta ctcctactag ctgaggaggg actagtggtg agaaataagg
     2521 aagaaatgac ctatttacag cctttgagag aagaattgag cctataattt ctcttataaa
     2581 gggagaattt tctgaaaaat catgatataa tggacgagac tatagataaa ggatagagag
     2641 taatgacatt agtttatcaa tcaacgcgtg atgccaacaa tacagtaact gccagccaag
     2701 caattttgca aggtttggcg acggacggcg gtttgtttac accggttact tatccaaagg
     2761 tagatttgga ctttgacaaa ttgaaagatg cttcttatca ggaagttgct aagctagttt
     2821 tgtcagcatt tttagatgac tttacagctg aggagttgga ctactgtatc aacaatgcct
     2881 acgatagcaa atttgatact ccagctattg caccattagt gaaattagat gggcaataca
     2941 atttggaact tttccatggt tcaacgattg cctttaagga tatggccttg tctattttgc
     3001 catactttat gacgactgct gctaagaaac atggtttgga gaacaagatt gttatcttga
     3061 cagcgacatc tggtgacacg gggaaagctg ctatggcggg gtttgcggat gtgcctggta
     3121 ctgagattat cgtcttttat ccaaagggtg gtgtcagcaa ggtacaagag ttgcaaatga
     3181 ccactcagaa tggtgacaat actcatgtta tcgctataga tggtaacttt gacgatgcgc
     3241 aaaccaacgt gaagcacatg tttaacgacg tggctcttcg tgaaagatta gcggccaaca
     3301 agttgcaatt ttcatctgct aactctatga atatcggtcg tttggtgcca cagattgttt
     3361 attatgttta tgcctatgct cagttggtca agactggtga gatcgtggct ggtgataaga
     3421 ttaacttcac agtaccaaca ggaaactttg gaaatatctt ggctgccttt tatgccaaac
     3481 aaatcggtct cccagttggt aaattgatct gtgcttcaaa tgataacaat gttttgacag
     3541 acttcttcaa gacacgtgtt tacgacaaga aacgtgagtt taaggtaaca accagcccat
     3601 ctatggatat cttggtatct tcaaacttgg agcgtttgat tttccatctt ttggggaatg
     3661 atgcggttaa gacggctgaa ctcatgaata ccttgaatac acaaggacaa tatgaactga
     3721 ctgattttga tgtagagatt ctggagctct ttgcagctga atatgcgact gaggaagaaa
     3781 cagcggcaga aatcaagcgt gtttatgagt tagattctta tattgaggat ccacatacgg
     3841 cggttgcctc agcagtttat agaaaatacc aagcggttac tgatgatgcg actaagacag
     3901 tgattgcttc aacagctagt ccctacaagt tcccagtagt tgcagtagaa gctgtaactg
     3961 gaaaagcagg tttaacagac tttgaagctt tggctcaatt acatgaaatc tcaggcgttg
     4021 cagtgccacc agcagttgat gggcttgaga cagctcctgt tcgtcacaag acaacagtgg
     4081 cagctgctga catgcaagta gcggttgagg cttatttagg actttaagat agagggagta
     4141 aactcggttg ggaaaccaac tgagtttctt ttcatcagga ggagagattg tttaagaaaa
     4201 ataaagacat tcttaatatt gcattgccag ctatgggtga aaactttttg cagatgctca
     4261 tgggaatggt ggacagttat ttggttgctc atttaggatt gatagctatt tcaggggttt
     4321 cggtagctgg taatattatc accatttatc aggcgatttt catcgctctg ggagctgcta
     4381 tttccagtgt tatttcaaaa agcatagggc agaaagacca gtcgaagttg gcctatcatg
     4441 tgactgaggc gttgaagatt accttactat taagtttcct tttaggattt ttgtccatct
     4501 tcgctgggaa agagatgata ggacttttgg ggacggagag ggatgtagct gagagtggtg
     4561 gactgtatct atctttggta ggcggatcga ttgttctctt aggtttaatg actagtctgg
     4621 gagccttgat tcgtgcaacg cataatccac gtctgcctct ctatgttagt tttttatcca
     4681 atgccttgaa tattcttttt tcaagtctag ctatttttgt tctggatatg gggatagctg
     4741 gtgttgcttg ggggacaatt ctgtctcgtt tggttggtct tgtgattttg tggtcacaat
     4801 taaaactgcc ttatgggaag ccaacttttg gtttagataa ggaactgttg accttggctt
     4861 taccagcagc tggagagcga cttatgatga gggctggaga tgtagtgatc attgccttgg
     4921 tcgtttcttt tgggacggag gcagttgctg ggaatgcaat cggagaagtc ttgacccagt
     4981 ttaactatat gcctgccttt ggcgtcgcta cggcaacggt catgctgttg gcccgagcag
     5041 ttggagagga tgattggaaa agagttgcta gtttgagtaa acaaaccttt tggctttctc
     5101 tgttcctcat gttgccccta tcctttagta tatatgtctt gggtgtacca ttaactcatc
     5161 tctatacgac tgattctcta gcggtggagg ctagtgttct agtgacactg ttttcactac
     5221 ttggaacccc tatgacgaca ggaacagtca tctatacggc agtctggcag ggattaggaa
     5281 atgcacgcct ccctttttat gcgacaagta taggcatgtg gtgtatccgc attggaacag
     5341 gatatctgat ggggattgtg cttggttggg gcttacctgg tatttgggca gggtctctct
     5401 tggataatgg ttttcgctgg ttatttctac gctatcgtta ccagcgctat atgatcttga
     5461 aaggatagga aatgcaaaaa acagctttta tttgggattt agacgggact ttattggact
     5521 cttacgaagc gattttatca gggattgagg agacttttgc tcagttttct attccttatg
     5581 ataaggagaa ggtgagagag tttatcttca agtattcggt gcaagatttg cttgtgcggg
     5641 tggcagaaga tagaaatctg gatgttgagg tgctaaatca ggtgcgtgcc cagagtctgg
     5701 ctgagaagaa tgctcaggta gttttgatgc caggtgcgcg tgaggtgcta gcttgggcag
     5761 acgaatcagg aattcagcag tttatatata ctcataaggg gaacaacgct tttaccattc
     5821 tcaaggactt gggggtggaa tcctatttta cagagatttt aaccagtcag agtggctttg
     5881 tgcggaagcc aagtccagaa gcggctacct atctgctaga taagtatcag ttgaattctg
     5941 ataatactta ttatataggg gatcggactc tggatgtgga atttgcccag aatagtggga
     6001 ttcaaagtat caacttttta gagtctactt atgaagggaa tcacaggatt caagcgttag
     6061 cagatatttc ccgtattttt gaggctgaac gataaaaaga ttgtgtcagt tttgtgacag
     6121 agacctaaca aactatttca agtaacctag tttgttacaa ggaatagaca gttctgttaa
     6181 ataggcccga gagggctttt tttctacatt ttttgtgtta tcatagacag gtactcattt
     6241 gaaaggattt gaaagaatga agaaaagaat gttattagcg tcaacagtag ccttgtcatt
     6301 tgccccagta ttggcaactc aagcagaaga agttctttgg actgcacgta gtgttgagca
     6361 aatccaaaac gatttgacta aaacggacaa caaaacaagt tataccgtac agtatggtga
     6421 tactttgagc accattgcag aagccttggg tgtagatgtc acagtgcttg cgaatctgaa
     6481 caaaatcact aatatggact tgattttccc agaaactgtt ttgacaacga ctgtcaatga
     6541 agcagaagaa gtaacagaag ttgaaatcca aacacctcaa gcagactcta gtgaagaagt
     6601 gacaactgcg acagcagatt tgaccactaa tcaagtgacc gttgatgatc aaactgttca
     6661 ggttgcagac ctttctcaac caattgcaga agctccaaaa gaagtagcat caagttcaga
     6721 agttacaaag acagtgattg cttctgaaga agtggcacca tctacgggca cttctgtccc
     6781 agaggagcaa acggccgaaa caactcgccc agttgaagaa gcaactcctc aggaaacgac
     6841 tccagctgag aagcaggaaa cacaagcaag ccctcaagct gcattagcag tggaagcaac
     6901 tacaacaagt tcagaagcaa aagaagtagc atcatcaaat ggagctacag cagcagtttc
     6961 tacttatcaa tcagaagaaa cgaaagtaat ttcaacaact tacgaggctc cagctgcgcc
     7021 cgattatgct ggacttgcag tagcaaaatc tgaaaatgca ggtcttcaac cacaaacagc
     7081 tgcctttaaa gaagaaattg ctaacttgtt tggcattaca tcctttagtg gttatcgtcc
     7141 aggagacagt ggagatcacg gaaaaggttt ggctatcgac tttatggtac cagaacgttc
     7201 agaattaggg gataagattg cggaatatgc tattcaaaat atggccagcc gtggcattag
     7261 ttacatcatc tggaaacaac gtttctatgc tccattcgat agcaaatatg ggccagctaa
     7321 cacttggaac ccaatgccag accgcggtag tgtgacagaa aatcactatg atcatgttca
     7381 cgtttcaatg aatggataaa cccgacttga taacatcatt ttgacgaatg agatctagct
     7441 ttcgtgatgg aaagcgattc tcgttcgttt tttctttgtc atactcttcg aaaatctctt
     7501 caaaccacgt cagttttatc tgagacctca aagctgtgct ttgagcaacc tgcgactagc
     7561 ttcctagttt gctttttgat tttcattgag tatcaatttg aatggaaaat ggaaagttat
     7621 catcttgtaa tgagttaagc aacattcttg caatctattt tactttatat cacaattaat
     7681 tagtcaaata ttgataaatc aataaaaaga gaggggaaga aatgctagag attcaagatt
     7741 tactgtatca actccgcttg tctgagcaag cgagtacgca attgtttgaa aaaaggcttg
     7801 ggattagttt gacacggtat cagattttac tgtttttgct ggagcattct ccttgtaacc
     7861 aaatggcggt tcaggagcgt ttgaaaattg atcaggctgc tttgacacgg catttcaaaa
     7921 ttttggaaac ggaaggtttg gtggagcgtc atcgtaatcc tgaaaatcag cgggaagtgt
     7981 tggtagaggc tgcgaagtat gccaaggagc agttagtggt gaatccccct ctgcaacata
     8041 tcagggttaa ggaagagata gaaagtatct taacagagtt tgagagaaca gaactcagcc
     8101 gtttattaaa taaattggtt ttgggtattg aaaatataga aatttaagga gaaatagatg
     8161 tcaattattt taacaacgat cgttgctttg gagcattttt acatttttta tttggaaagt
     8221 attgccacgc aatcagatgc gactagtcgt gtatttaata tggaaaagga agaattggct
     8281 catccgtcag taagttcatt gttcaaaaat caaggaattt ataaggctct gctaggagtc
     8341 tttctcttgt atgtcattta tttctcacag aatttagaaa ttgtgactat ttttgtctta
     8401 tttgtgattg gtgctgcgac ttacggctct ttaacagcgg ataaaaaaat tattttgaaa
     8461 caaggtggat cagctatttt ggccttgatt agtattttac tctttaaata cacttgaagg
     8521 tcgattctaa tctcgctaat cctttttaat ccagaataag ggaaatatgt tatacttgtt
     8581 tttaagaaaa aagtttcatt gaattggttt tgaggagtta gaaatgaaag tattagtgac
     8641 aggttttgag cccttttgag gccattaaag gtttaccagc tgaaatccat ggtgctgagg
     8701 tccgttggct agaggtgccg acagtttttc acaaatctgc tcaagtattg gaagaagaga
     8761 tgaatcgtta tcaacctgac tttgtccttt gtattgggca agctggtgga agaactagtt
     8821 tgacacctga acgagtggcc attaatcaag acgatgcacg tacttctgat aacgaagata
     8881 atcaaccgat tgaccgtccc attcgcccag atggtgcttc ggcctacttt agtagtttgc
     8941 cgattaaagc gatggttcaa gctataaaaa agaaggatta ccggcctctg tttccaatac
     9001 ggcagggact tttgtctgca gccatttgat gtatcaggct ctctatttgg tagaaaagaa
     9061 atttccatat gttaaggcag gttttatgca tattccttat atgatggaac aggtggtgaa
     9121 cagaccgact actccaacta tgagtttagt ggatattcgg cgagggatag aagcagcaat
     9181 cggcgctatg atagaacatg gagatcagga actcaagttg gtaggcggag aaattcattg
     9241 atagaaaaaa gcttgagggg aaaaccttca agcttttgga cgttttcgag ccaatactgc
     9301 tcggtaaaac ataattttag tgcattggat ataaggtagg agtgaaaaac tagcaatgcc
     9361 aaaggtaatc caattgagga agtaccaagg aagaagctgt aaatctagga caaagtgctg
     9421 gaacttgtag cccttcataa aggaacggct agtttttagg attcgtcttg gtgggacctg
     9481 tcctaggtct agactatgac agagaagaaa ttccacctgt gaataggcat aatactgtgg
     9541 aatatagagg atatttccta caatgatcaa gatgagactt gcaagaaagt agagtccaaa
     9601 gaccatgagg aaacgctcgg tttcaactga tgagagatct agatttggaa actcaggatg
     9661 tagggtgacg aattttttgg ctaaaaagct actataaaag aggaggtaaa tcccaagtaa
     9721 attagggata ctccataaaa agagatagaa acgtttgaga agtagggtca aaaaggtttg
     9781 agaaaagcgc tcctcatcaa agagagctag gctgtttttt acagatggct ccgttttaga
     9841 atctttcatg agtgtcagtg ttgcatagac ggaactggtc aaaagaatag tcccgataaa
     9901 ggagactagt agaggaaaga ggtaggcttg aagtatttgg ccaagtatgc tgaaaaatgg
     9961 ctgttctaaa acagtcccgt ggatccgaga taagggatta agaaaaccag ataagatgac
    10021 cagcatactg ggaaggatat agaggagaaa gagacggggg gtgtcagcct gaaaatgttt
    10081 tgactcctga cgaattgttt ttaaatcaat ttttggatag ttcattctct tattatacca
    10141 tagttcttat acatagttcg tgacagttcc tacttttttt gataaaatca tacagtgtgt
    10201 ccttgggcac actgtatgaa ctgggactgt ctttcccagc ttcggaggta aaaaatgtca
    10261 gattcaccaa tcaaatatcg tttgattaag aaagaaaaac acacaggagc tcgtctagga
    10321 gaaatcatca ctccccacgg tacctttccg acacctatgt ttatgccagt tgggacacaa
    10381 gccactgtca aaactcagtc acctgaagaa ttgaaggaga tgggttcggg aattatccta
    10441 tcaaacacct atcatctctg gcttcgccct ggagatgaac tcattgcacg cgctggtggt
    10501 ctccacaagt tcatgaattg ggaccagcct atcttgacag atagtggtgg ttttcaggtt
    10561 tattctttag cagatagccg taatatcaca gaagaaggag taacctttaa aaatcatcta
    10621 aatggttcta agatgttcct atccccagaa aaagccatct ctattcagaa taatctgggt
    10681 tcagacatca tgatgtcctt tgatgaatgt cctcagtttt atcaacctta tgactacgtt
    10741 aagaaatcga tcgagcgtac cagccgttgg gctgagcgtg gtttgaaggc tcaccgtcgt
    10801 ccacatgacc aaggtttgtt tggaattgtg caaggtgcag gatttgaaga ccttcgccgc
    10861 caatcagctc atgatcttgt cagcatggat ttctcaggct actctatcgg tggtttggca
    10921 gtgggagaaa cccatgaaga gatgaatgcg gtcttggact ttacaactca actgctgcct
    10981 gaaaataaac ctcgttatct gatgggtgtg ggagcgccag atagcttgat cgatggggtc
    11041 attcgtgggg tggatatgtt tgactgtgtc ttaccgactc gaattgctcg taacgggact
    11101 tgtatgacca gtcaaggacg tttggttgtg aaaaatgccc agtttgctga ggactttacg
    11161 ccactggatc ctgagtgtga ttgctacaca tgtaataact atacacgcgc ttaccttcgt
    11221 cacctgctca aggctgatga aacctttggt atccgcttga ctagctacca caatctttac
    11281 ttcttgctta acttgatgaa gcaagtgcga caagccatca tggatgacaa tctcttggaa
    11341 ttccgtgagt attttgtgga aaaatatggc tataataagt caggacgtaa tttctaaaat
    11401 ggaattgata taagctaaaa atcctaagtt ttctcttagg atttttcttc tttttttgat
    11461 agaataaagt gtacaatgaa aggaagaata aactcgtatg cgcattaaat ggttttcctt
    11521 ggttaggatt acaggtttac ttttggtact cttgtatcac ttctttcaga cgatctttcc
    11581 tggaggattt ttcggggtag atgtcttttt cacattttca ggtttcctga ttacagctct
    11641 actcattgaa gaattttcta aaaaccatga gattgatttg ataggatttt ttagaagacg
    11701 cttttatcgg attgtgccac ctgtggtttt gatggtcttg gtgaccatgc cttttacttt
    11761 cttggttcgc caagactatg ttgctggaat tggtggccag attgcgagcg tcttaggctt
    11821 tatgaccaac ttctatgaac tcctaacagg tgggagttat gaatctcagt tcattcctca
    11881 tttgtttgtt cataattgga gtttggcagt tgaggttcac tactatattc tttggggatt
    11941 ggcagtttgg ttcttatcca aacaagctaa atcaaatggt cagttgaagg ggatggtctt
    12001 tctcttatct gctgttgcct tcttgatcag tttcttctcc atgtttattg gtagttttct
    12061 agtgacctct tattcctctg tttatttctc cagtttaact catgtctatc cattcttttt
    12121 gggaagtatg ttagcaacta ttgtaggcgt tcgtcagacg acttccctcg tcaagcagtt
    12181 ggataaaatc tgggatttac gaaagacttt ggtagttttt ggaggaggct ttggtttcct
    12241 agttcttttg actttctttg tcaaattcac ttatcttttt gcctatctta tcggcttctt
    12301 acttgccagt cttgcagctc ttgccatgat tctggcggcg cgtgtcttac atgaaaagac
    12361 acatcatata caggagccga agattatcag ctttttagcg gatactagct atgcggttta
    12421 tcttttccat tggcctttct atatcatttt ctcacagttg acatcaaatc ttcttgctgt
    12481 attactgact ctgatttgtt cttatggctt tgccagtctg tcattttatg tattggaacc
    12541 ttggattgca ggcaagaaca cacctattgt ccaaaccctt cgtcccctgc cttatattca
    12601 cgcaattctt gcagcaggta caggaatctt gaccatcatt gtctgcacgg tgaccttgtt
    12661 ggcaccacaa gtgggagcgt ttgagacaga cttgactgtc aatggcttga agcaagctgc
    12721 aacaaatatt ggccagacca aggtgatggc agaacgggca gatgcaaaca gtttgggaat
    12781 tgctgatggc actatgttaa ttggtgactc agtggcttta agggcaaata cagcactaca
    12841 gacagctctt cctggagcac agattaacgc gcaggtcagc gtaacaacca agaccgcaaa
    12901 tgaaatcatg ctaaataata gccagaataa atttttacct aagacggtgg tcattgcgac
    12961 tggggtaaat aatcctgaga attacaagga tgactgggac agtatcgtga aaaatcttcc
    13021 taagggacac catatgattt tggtgactcc ttatgaggga gataagacaa aagagaccta
    13081 tgccatcgtt gagaaggctg ctgcctatat gagagaattg gcagagaaga caccttacat
    13141 tacgatagca gattggaatc aagttgcgaa agagcatcca gaaatttggg ctggaacaga
    13201 ccaggttcat ttcgggagtg agagtagcac tatcgaagca ggagcaaaat tgtatgcaga
    13261 tacgattgcc acagctttgc agacagctca agacaagccg gttaaatcaa aataacttgt
    13321 attaaaaaag agaagagttg gagaaatcca gctcttttaa aatatctcca aaaaataggt
    13381 ctataccatt tacaaataaa aaagaaaggt ttataatgta attgacataa taaattgtag
    13441 aatcaatctt ttaaggaggt taacattatg cctaactata ttaaagcgga tcagtttttc
    13501 tacccacacg gagttcgtcg aggtggttac ttggaacttg tggacggcaa gtttgggaaa
    13561 catgtagagc agattcctga aggggctgag gtgattgact atacaggtta tagcattgcc
    13621 ccaggtcttg tggatactca tattcatgga tatgcaggtg tagatgtgat ggacaacaac
    13681 attgaaggta cattgcatac tatgagtgaa ggacttctta gtaccggtgt taccagtttc
    13741 ttacccacaa ctttaacagc cacttatgag caattgcttg cagtcactga aaatcttgga
    13801 aaccattata aagaagcaac aggtgctaag attcgtggga tttattatga aggtccatat
    13861 ttcacagaaa cttttaaggg ggcacaaaat ccaacttata tgagagaccc gggtgttgag
    13921 gagtttcatt cttggcaaaa agcggcaaat ggcttgctta ataaaattgc ccttgcacca
    13981 gaacgtgatg gggtggaaga ctttgttcgt acagttacgg gcgaaggtgt gacggttgct
    14041 cttggacatt caaacgcgac ttttgatgaa gccaaaaaag cagtcgatgc tggagcgagt
    14101 gtttgggtgc atgcctacaa tggaatgcgt gggttgactc accgtgaatt gggtatggtt
    14161 ggagccatgt accaattgcc acatacctat gcagagttga tctgtgatgg tcaccacgta
    14221 gatccaaagg cttgcgaaat tcttatcaaa caaaaaggaa cagaaaacat cgctcttatc
    14281 acagactgta tgacagctgg gggattggaa gacggagatt atatgttggg agaattccca
    14341 gttgtcgttg caaatggaac tgcacgcctc aaatcgacag gtaacttggc aggttctatc
    14401 ctcaaactca aagatggttt gaagaatgtg gtcgaatggg gaattgcgaa tccgcatgaa
    14461 gcagtcatga tggccagctt caacccagct aaatccgttc acatcgatga cgtctgtggc
    14521 caaatccgtg aaggctacga cgctgacttc atcgtattag ataaagattt ggaattggta
    14581 gcaacctacc tagatggcgt aaaacgttat caagcataag agagaaagca gaagttagag
    14641 actaacttct gcttttttat gcagggtact ttactggtaa ataaaaagtt aaaaaaatca
    14701 caaaaaaagc ttgaagaaac aaagaaaaag gcttacaatt gaactataaa tattacaaat
    14761 aaaaaaacgg aggagtgctt tatgaaagcc tatacttatg ttaaaccagg acttgcttct
    14821 tttgttgatg tagacaaacc agttattcgc aagccaacag acgctattgt gcgtattgta
    14881 aaaaccacta tttgtggaac agacctccat attatcaaag gggatgttcc tacttgccaa
    14941 agtggtacca ttcttggcca cgaagggatt gggattgttg aagaagttgg ggaaggagtt
    15001 tccaacttca aaaaaggtga caaggtcttg atttcttgcg tctgtgcctg tggtaaatgc
    15061 tactactgta aaaaaggaat ttatgctcac tgtgaagacg aagggggctg gattttcggt
    15121 cacttgattg atggtatgca ggctgaatat ctacgtgtcc ctcatgcaga taatactctt
    15181 taccatactc tagacgactt gtcagatgaa gctttggtta tgctgtcaga cattctgcct
    15241 actggatatg aaattggtgt cttaaaaggg aaagtagaac ctggttgcag cgtagccatt
    15301 attggttcag gtccagttgg attggctgct cttttaacag cccaattcta ttcaccagct
    15361 aaattgatta tggtagacct agacgataac cgcttggaaa ctgccctatc attcggtgcg
    15421 actcataagg ttaattcttc agaccctgaa aaagccatta aagaaattta tgatttgaca
    15481 gatggtcgtg gtgtggatgt cgctatcgaa gctgttggta ttcctgcaac atttgatttc
    15541 tgtcaaaaga ttatcggtgt agacggaacg gttgccaact gtggtgtgca tggtaaacca
    15601 gttgaattcg atttagataa actttggatt cgcaacatca atgtaacaac tggtttggta
    15661 tctacaaata cgactccaca attgttgaaa gcgcttgaaa gtcataagat tgaaccagaa
    15721 aaattggtaa ctcactattt caaactcagt gaaattgaaa aagcctacga agtcttcagt
    15781 aaggcagcag accaccatgc cattaaggtc attatcgaaa acgatatctc agaagcctaa
    15841 gtagtaaaaa tatttttgta cataagtaaa tagaaattca gtcatccatc agatggctgg
    15901 attttttatc aaaaaattaa gaaatgagca tatttctttc cttgtctggc ggaattggtt
    15961 ataatatacg gtacaaagga atgaatgaat atgtatcgtg ttatagaaat gtacggagat
    16021 tttgaaccgt ggtggttctt agaaggttgg gaagaagata ttgtagcaag tagaaaattt
    16081 gaccagtatt atgatgctct caaatactac aaaacttgct ggtttagatt ggaacaagaa
    16141 tcccctcttt ataaaagtag aagcgacttg atgaccattt tttgggaccc ggaagaccaa
    16201 cgctggtgtg atgaatgtga tgagtattta caacaatacc attctttggc tcttttgcag
    16261 gatgagcagg ttatcccaga cgaaaaacta cgctcaggct atgaaaaaca aaccagtcag
    16321 gaaaggaatc gttcttgccg tatgaaatta aaatagagaa aagtaacttt tttggagttg
    16381 ctttttttat ttttctaacg ctttgcgaat agtataggtg aggaggtaag tatggttcaa
    16441 gaaattgcac aagaaatcat tcgctcggct cggaaaaaag gggcgcaaga catttatttt
    16501 gtccccaagt tagacgccta tgagcttcat atgagggtag gagacgagcg ctgtaaaatt
    16561 ggtagctatg attttgaaaa gtttgcagcc gttatcagtc actttaagtt tgtggcgggt
    16621 atgaatgtgg gagaaaaaag acgtagtcaa ctgggttcct gtgattatgc ctatgaccag
    16681 aagatggcgt ctctacgttt atctactgta ggcgattatc gggggcatga gagtttggtt
    16741 atccgtttgt tgcacgatga ggagcaggac ttgcattttt ggtttcagga tattgaagaa
    16801 ttaggcaagc agtacaggca acggggactc tatctttttg ctggtccggt tgggagtggt
    16861 aagacgacct tgatgcatga attgtccaag tcactcttta aaggacagca agttatgtcc
    16921 atcgaagatc ctgtcgaaat caagcaggac gacatgcttc agttgcagtt gaacgaagca
    16981 atcggtctaa cctatgaaaa tctaatcaaa ctttccttgc gtcatcgacc agatctcttg
    17041 attatcggag aaattcgtga catcgagacg gcgcgtgcag tggtcagagc tagtttgaca
    17101 ggtgcgacag tcttttcaac cattcacgcc aagagtatcc gaggtgttta tgagcgtctg
    17161 ctggagttgg gtgtgagtga agaagaattg gcagttgttc tgcaaggagt ctgctaccag
    17221 agattaatcg ggggaggagg aatcgttgac tttgcaaaca gagattatca agaacaccaa
    17281 gcagccaagt ggaatgagca aattgaccag cttcttaaag atggacatat cacaagtctt
    17341 caggctgaga cggaaaaaat tagctacagc taagcaaaaa aatatcatca ccctatttaa
    17401 caatctcttt tctagcggtt ttcatctggt ggagactatc tcctttttag ataggagttc
    17461 cttgttggac aagcagtgtg tgacccagat gcgtacaggc ttgtctcagg ggaaatcatt
    17521 ctcagaaatg atggaaagtt tgggatgttc aagtaccatt gtcactcagt tatctctagc
    17581 tgaagttcat ggcaatcttc acctgagttt gggaaagata gaagaatatc tagacaatct
    17641 ggccaaggtc aagaaaaagt taattgaagt agcgacctat cctttgattt tgctgggttt
    17701 tcttctctta attatgctgg ggctacggaa ttacctgctc ccacaactgg atagtagcaa
    17761 tattgccacc cgaattatcg gtaatctgcc acaaattttt ctaggcatgg tagggcttgt
    17821 ttccgtgctt gcccttttag cactaacttt ttataaaaga agttctaaga tgagtgtctt
    17881 ttctatctta gcacgccttc cctttattgg aatctttgtg cagacctact tgacagccta
    17941 ttatgcacgt gaatggggga atatgatttc acagggaatg gagctgacgc agatttttca
    18001 aatgatgcag gaacaaggtt cccagctctt taaagaaatc ggtcaagatc tggctcaaac
    18061 cctgaaaaat ggccgtgaat tttctcagac gataggaacc tatcctttct ttaggaagga
    18121 attgagtctc atcatagagt atggggaagt taagtccaag ctgggtagtg agttggaaat
    18181 ctatgctgaa aaaacttggg aagccttttt tacccgagtc aaccgcacca tgaatttggt
    18241 gcagccactg gtttttatct ttgtggcact gattatcgtt ttactttatg cggcaatgct
    18301 catgcccatg tatcaaaata tggaggtaaa tttttaaaat gaaaaaaatg atgacattct
    18361 tgaaaaaagc taaggttaaa gcttttacat tggtggagat gttggtggtc ttgctgatta
    18421 tcagcgtgct tttcttgctc tttgtaccta atctgaccaa gcaaaaagaa gcagtcaatg
    18481 acaaaggaaa agcagctgtt gttaaggtgg tggaaagcca ggcagaactt tatagcttgg
    18541 aaaagaatga agatgctagc ctaagcaagt taaaagaaga tggacgcatc acggaagaac
    18601 aggctaaagc ttataaagaa tacaatgata aaaatgtggg agcaaatcgt aaagtcaatg
    18661 attaaggcct ttaccatgct ggaaagtctc ttggttttgg gtcttgtgag tatccttgcc
    18721 ttgggcttgt ccggctctgt tcagtccact tttgcggcgg tagaggaaca gattttcttt
    18781 atggagtttg aagaactcta tcgggaaacc caaaaacgca gtgtagccag tcagcaaaag
    18841 actaatctaa atttagatgg gcagacgctt agcaatggca gtcaaaagtt gacagttcct
    18901 aaaggaattc aggcaccatc aggccaaagt attacatttg accgagctgg gggcaattcg
    18961 tccctggcta aggttgaatt tcagaccagt aaaggagcga ttcgctatca attatatcta
    19021 ggaaatggaa aaattaaacg cattaaggaa acaaaaaatt agggcagtga ttttactgga
    19081 agcagtagtc gctctagcta tctttgccag cattgcgacc ctccttttgg gacaaattca
    19141 aaaaaatagg caagaggaag caaaaatctt gcaaaaggaa gaagtcttga gggtagctaa
    19201 gatggccctg cagacggggc aaaatcaggt aagcatcaac ggagttgaga ttcaggtatt
    19261 ttctagtgaa aaaggattgg aggtctacca tggttcagaa cagttgttgg caatcaaaga
    19321 gccataaggt caaggctttt accttgttag aatccctact tgccctcatt gtcatcagtg
    19381 ggggattact cctttttcaa actatgagtc agctcctcat ttcagaagtt cgctaccagc
    19441 aacaaagcga gcaaaaggag tggctcttgt ttgtggatca acttgaggca gaattagacc
    19501 gttcgcagtt cgaaaaagta gaaggcaatc gcctatacat gaagcaagat ggcaaggaca
    19561 tcgccatcgg taagtcaaag tcagacgatt ttcgtaaaac gaatgctcgt ggtcgaggtt
    19621 atcagcctat ggtttatggc ctcaaatcag ctcagattac agaggacaat caactggttc
    19681 attttcgttt ccagtttcaa aaaggcttag aaagggagtt catctatcgt gtggaaaaag
    19741 aaaaaagtta aggcaggtgt tctcctctac gcagtcacca tagcagccat ctttagtctt
    19801 ttgttgcaat tttatttgaa ccgacaagtc gcccactatc aagactatgc tttgaataaa
    19861 gaaaaattgg ttgcttttgc tatggctaaa cgaaccaaag ataaggttga gcaagaaagt
    19921 ggggaacagg tttttaatct aggtcaggta agctatcaaa acaagaaaac tggcttagtg
    19981 acgagggttc gtacggataa gagccaatat gagtttctgt ttccttcagt caaaatcaaa
    20041 gaagagaaaa gagataaaaa ggaagaggta gcgaccgatt caagcgaaaa agtggagaag
    20101 aaaaaatcag aagagaagcc tgaaaagaaa gagaattcct agtcaattca actataatgc
    20161 gttgaatcca gaatagtcca ctgtagtttc tagaaaattg ctggaaatgg atgttaagct
    20221 ccaattcatt tgtttatatc ttatttcagt ttactatact ttgtgctaaa ttaaagatat
    20281 gaaacatgat tttaaccaca aagcagaaac tttcgatttc cctaaaaata tcttcctcgc
    20341 aaacttggta tgtcaagcag ccgagaaaca gattgatctt ctatcagaca aagaaatttt
    20401 agatttcggt ggtggcacgg gtctattagc cttgccccta acccctagcc aagcaggcta
    20461 agtcagtcac tcttgtagac atttctgaga aaatgttgga gcaagctcgt ttgaaagtgg
    20521 agcagcaagc aatcaagaat atccagtttt tggagcaaga tttaccgaaa aatcccttgg
    20581 agaaagagtt tgattgcctt gctgttagtc gggttcttca tcatatgcct gatttggatg
    20641 cggctctctc actgtttcat caacatttga aggaagatgg gaaactcatc attgctgatt
    20701 ttaccaagac agaagctaat catcatggat ttgatttagc tgaactggaa aacaagctaa
    20761 ttgagcatgg tttttcatct gtgcatagtc agattctcta tagcgctgaa gacctgtttc
    20821 aaggaaatca ctcagaattc tttttaatag tagcccaaaa atcactcgcc tagtcaggga
    20881 gtgatttttc tataagaatg gaaaaaagaa gggaaatttg ataagatagg aatatggatt
    20941 ttgaaaaaat tgaacaagct tatacctatt tactagagaa tgtccaagtc atccaaagtg
    21001 atttggcgac caacttttat gacgccttgg tggagcaaaa cagcatctat ctggatggtg
    21061 agactgagct agaacaggtc aaagacaaca atcagaccct taagcgttta gcactacgca
    21121 aagaagaatg gctcaagacc taccagtttc tcttgatgaa ggctgggcaa acagaaccct
    21181 tgcaggccaa tcaccagttt acaccggatg ctattgcttt acttttggtg tttattgtgg
    21241 aagagctgtt taaagaggag gaaattacta tcctcgaaat gggttctggg atgggaattt
    21301 tgggcgctac tttcttgacc tcgcttacta aaaaggtgga ttatttggga atggaagtgg
    21361 atgatttgct gattgatctg gcagctagca tggcagatgt aattggtttg caggctggct
    21421 ttgtccaagg agatgccgtt cgtccacaaa tgctcaaaga aagcgatgtg gtcatcagtg
    21481 acttgcctgt tggctattat cctgatgatg ccgttgcgtc gcgccatcaa gttgcttcta
    21541 gccaagaaca tacttacgcc catcacttgc tcatggaaca agggcttaag tacctcaagt
    21601 cagacggata cgctattttt ctagctccga gtgatttgtt gaccagtcct caaagtgatt
    21661 tgttaaaaga atggctgaaa gaagaggcga gtctggttgc tatgattagt ctgcctgaaa
    21721 atctctttgc taatgctaaa caatctaaga ctatttttat cctacagaag aaaagtgaaa
    21781 tagcagtgga gccttttgtt tatccacttg ctagcttgca agatgcaagt gttttaatga
    21841 aatttaaaga aaattttcaa aaatggactc aaggtactga aatataaaat agattttgtt
    21901 ataatagttg aaaacgctta aaaaggggta tcatgttatg acaaaaacaa ttgcaatcaa
    21961 tgcaggaagt tcaagtttga aatggcaatt atacttaatg ccagaggaaa aagtgttagc
    22021 caaaggtttg attgaacgta tcggtttgaa agattcaatt tcaactgtaa aatttgacgg
    22081 ccgttctgaa caacaaattt tggatatcga aaatcataca caagctgtta aaattttatt
    22141 ggatgacttg attcgtttcg atattatcaa ggcttatgac gagattacag gtgttggaca
    22201 tcgtgttgtt gctggtggag aatatttcaa agaatcaaca gttgttgagg gagatgtttt
    22261 agaaaaagtt gaagagttga gtttgttggc tcctctacac aacccggcca atgcagcagg
    22321 tgttcgtgcc ttcaaggaat tgttgccaga cattaccagt gtagttgttt ttgatacttc
    22381 cttccacaca agtatgccag agaaagctta tcgctaccct ctaccaacaa aatattacac
    22441 agaaaacaag gttcgtaaat acggtgctca tggtacaagt caccagtttg tagcaggaga
    22501 agctgcaaaa ctcttgggac gtccattaga agacttgaag ttaattacct gtcatattgg
    22561 taacggaggc tcaattacag ctgtgaaagc cggcaaatct gtagacactt ctatggggtt
    22621 cactcctctt ggtggtatta tgatgggaac gcgtacaggg gatattgatc cagctatcat
    22681 tccttattta atgcaatata cagaggattt taacacacca gaagatatca gtcgtgttct
    22741 taaccgtgaa tcaggtcttt tgggagtttc tgctaattct agcgatatgc gcgatataga
    22801 agcagctgta gcagaaggga atcacgaggc tagcttggct tatgaaatgt atgttgaccg
    22861 tatccaaaaa catatcggtc agtaccttgc agtgctaaat ggagcagatg ccattgtttt
    22921 cacagcaggt gtcggtgaaa atgcagagaa tttccgtcgt gatgtaatct cagggatttc
    22981 gtggtttggt tgtgatgttg atgatgaaaa gaatgtcttt ggcgttacag gagacatctc
    23041 aacagaggca gctaaaatcc gtgtcttggt tattccaaca gatgaagaat tagtcattgc
    23101 ccgtgacgtt gaacgcttga aaaaataagt gaaactaaaa aaatattcaa tacaaggagt
    23161 tgggaaagtt atttttccag cttctttttc tgatgaaatt gtccaaaacc ttgctatgat
    23221 tggctttttt gaaaaatatg gtataatagt agtaatttaa tagatggagt tgagttttga
    23281 agaaaaactt tcgtgtaaaa agagagaaag attttaaggc gattttcaag gaggggacaa
    23341 gttttgctaa tcgcaaattt gtggtctacc aattagaaaa ccagaaaaac cattttcgag
    23401 taggtctatc agttagcaaa aaactgggga atgccgtcac tagaaatcaa attaagcgac
    23461 ggattcggca tattatccag aatgcaaaag ggagtctggt agaagatgtc gactttgttg
    23521 tcattgctcg aaaaggagtc gaaaccttgg gatacgcaga gatggagaaa aatctactcc
    23581 acgtattaaa attatcaaag atttaccagg aaggaaatgg gagtgaaaaa gaaactaaag
    23641 ttgactagtt tgctaggact gtctctgtta atcatgacag cctgtgcaac taatgaggta
    23701 actagcgata ttacagccga atcggctgat ttttggagta aattggttta cttctttgcg
    23761 gaaatcattc gctttttatc gtttgatatt agtatcggag tggggattat tctctttacg
    23821 gtcttgattc gtacagtcct cttgccagtc tttcaggtgc aaatggtggc ttctaggaaa
    23881 atgcaggaag ctcagccacg cattaaggcg cttcgagaac aatatccagg tcgagatatg
    23941 gaaagcagaa ccaaactaga gcaggaaatg cgtaaagtat ttaaagaaat gggtgtcaga
    24001 cagtcagact ctctttggcc gattttgatt cagatgccgg ttattttggc cctgttccaa
    24061 gccctatcaa gagttgactt tttaaagaca ggtcagttct tatggattaa ccttggtagt
    24121 gtggatacaa cccttgttct tccgatttta gcagcagtat tcaccttttt aagtacttgg
    24181 ttgtccaaca aagctttgtc tgagcgaaat ggagctacga ctgcgatgat gtatgggatt
    24241 ccagtcttga tttttatctt tgcagtttat gcgccaggtg gagtcgccct atactggaca
    24301 gtgtctaatg cttatcaagt cttgcaaacc tatttcttga ataatccatt caagattatc
    24361 gcagagcgcg aggccgtagt acaggcacaa aaagatttgg aaaatagaaa aagaaaagcc
    24421 aagaaaaagg ctcagaaaac gaaataaata aggaggaatc tggtaatggt agtatttaca
    24481 ggttcaactg ttgaagaagc aatccagaaa ggattgaaag aattagatat tccaagaatg
    24541 aaggctcata tcaaagtcat ttctagggag aaaaaaggct ttcttggtct atttggtaaa
    24601 aaaccagccc aagtggatat tgaagcgatt agtgaaacga ctgttgtcaa agcaaatcaa
    24661 caggtagtaa aaggcgttcc gaaaaaaatc aatgatttga acgagcctgt gaagacggtt
    24721 agtgaagaaa ccgttgacct tggtcatgtg gttgatgcta ttaaaaaaat agaggaagaa
    24781 ggtcaaggta tttctgatga agtcaaggct gaaatcttaa aacatgaaag acatgccagc
    24841 actatcttag aagaaactgg tcacattgag attttaaatg aacttcaaat cgaggaagcg
    24901 atgagggaag aagcaggcgc tgatgacctt gaaactgagc aagatcaaac tgaaaatcaa
    24961 gacttgaaag agatgggctt gaaggtcgag caaagttatg atattgccca ggtggctacg
    25021 gatgtgactg cctatgttca agcgattgtg gatgacatgg atgttgaagc tacactttca
    25081 aatgattata accgtcgtag catcaatcta caaattgaca ccaacgaacc aggtcgtatt
    25141 atcggctacc atggtaaagt cttgaaggcc ttgcaactgt tggctcaaaa ttatctttac
    25201 aaccgctatt ccaaaacctt ctacgttaca atcaatgtca atgattatgt cgaacaccgt
    25261 gcagaagtct tgcagaccta tgcgcaaaaa ttggcgattc gtgttttaga agaaggacgt
    25321 agtcatcaaa cagatccaat gtcgaatagt gaacgcaaga ttatccaccg tattatttca
    25381 cgtatggatg gcgtgaccag ttactctgaa ggtgatgagc caaatcgcta tgtcgttgta
    25441 gatacagaat aagtaaaatc agggttgacc tgattttttg ctagctagag gaggttaaac
    25501 tgatgttgaa taagataaga gactatttag actttgctgg tttgcagtac cgtaatcctg
    25561 ataaagcggg agcagagcga gagaagatgc tggcattccg ccacaaagga caagaggccc
    25621 gaaaggcttt tacagaactg gccaaagcct ttcaagcaag ccatccagaa tggcaactcc
    25681 aacagactag tcagtggatg aatcaggccc agcgtttgag accacatttt tgggtttatc
    25741 tacagagaga cggacaagtg acagaaccta tgatggcctt acgtttgtat gggacatcta
    25801 ctgactttgg aatttctttg gaagtcagtt tcatcgaacg taagaaggat gagcaaacac
    25861 tgggcaagca ggccaaagtt ttagacattc caaccgttaa agggatttat tatctaacct
    25921 actctaatgg tcaaagtcaa cggtgggagg cgaatgaaga aaagcgtcgt actttacgcg
    25981 agaaggtgag aagtcaagaa gttcgaaaag ttttagtgaa ggtagatgtt cctatgacag
    26041 aaaattcgtc tgaagaagaa atcgtagaag gcttattgaa gtcttattct aaaattcttc
    26101 cctattatct agctacgaga aaataagata atttgtaaaa catcataaat catacagtcc
    26161 aagagtgaac agtccgctgt gtaattcttg gtctttttgt ttgcgctttc gcattatata
    26221 ataaacttac aaaaacaatt caaaaggaga acaattatgg aagtcgtttc aagtgttcta
    26281 aattggtttt ctagcaatat tttgcagaat cccgcatttt tcgtaggttt attggtgttg
    26341 ataggatatg cacttttgaa aaaacctgcc catgacgttt tttcagggtt tgttaaagca
    26401 acagtagggt atatgttgct taacgtgggt gctggtggtt tggttacaac ctttcgtcca
    26461 atcttagcag ctcttaacta caaattccaa attggtgcag cggttatcga cccttacttt
    26521 ggacttgctg cagcaaacaa caaaattgca gcagagtttc cagattttgt tggaactgca
    26581 actacagctc tattgattgg ttttggaata aatatcttgc tcgtagctct tcgaaagatt
    26641 acgaaggtaa gaaccctctt tattactggt cacatcatgg tacaacaagc tgcaacagta
    26701 tctcttatgg ttctattctt agtaccacaa ttgcgcaatg cttacggtac agcagcgatt
    26761 ggtatcatct gtggacttta ctgggcagtt agttcaaata tgactgttga ggcaactcaa
    26821 cgcttgactg gtggtggcgg atttgcgatt ggtcaccaac agcaatttgc aatctggttt
    26881 gtagataaag tagcaggacg ctttggtaag aaagaagaaa gtttagacaa tcttaaatta
    26941 cctaagttcc tctcaatctt ccacgataca gttgttgcat ctgctacctt gatgctcgta
    27001 ttcttcgggg ccattctttt aatcttgggt ccagacatta tgtctaataa agaagtcatc
    27061 acttcaggaa ctctattcaa tcctgctaaa caagatttct ttatgtacat tatccaaaca
    27121 gcctttacct tctcagttta cttgttcgtt ttgatgcaag gtgtccgaat gttcgtatct
    27181 gagttgacaa acgccttcca aggtatttca aacaaattgt tgccaggttc attcccagcg
    27241 gttgacgttg cagcttctta tggatttggt tctccaaatg ctgtcttgtc aggatttacc
    27301 tttggtttga ttggtcaatt gattacaatt gtcttgctca tcgtctttaa aaatccgatt
    27361 cttattatta caggatttgt accagtgttc tttgacaatg cagccattgc ggtctacgct
    27421 gataaacgcg gcggatggaa agcggctgtt atcctttcct ttatatcagg tgtccttcaa
    27481 gttgctctag gagctctttg tgtggccctt ctcgatttgg catcttatgg tggctaccat
    27541 ggaaatatcg actttgaatt cccatggctt ggatttggat atatcttcaa ataccttggt
    27601 attgttggtt atgtacttgt gtgtctcttc ttgcttgtta ttcctcaact tcaatttgcc
    27661 aaagcaaaag ataaagagaa atattacaac ggtgaagttc aagaagaagc ttagtatcta
    27721 gaaaaggaga aataaaatgg ttaaagtatt agcagcgtgc ggaaatggaa tgggttcatc
    27781 aatggttatc aagatgaagg ttgaaaatgc tctccgtaag cttaatcaaa cagattttac
    27841 agtcaattca tgcagtgtcg gtgaagctaa aggtttagca gtaggatatg acatcgtaat
    27901 cgcttctctt catttgattc aagaattgga agggcgaact aatgggaagt taattgggct
    27961 tgataacttg atggatgata aagaaatcac cgaaaaactc agtcaagcac tacagtaaaa
    28021 ggttggaggg ggctggacag aaactgagag ttatcgtttc tgtccttctc cctctttaaa
    28081 taaaggaggc agatatgaat ttaaaacaag ctttaattga caacgactcg atccgactag
    28141 gtttagaggc taacgattgg aaagaagcag tcaaggtagc agtagatccc ttgattgaaa
    28201 gtggggcaat tttgccagag tattacgatg ctatcattga atcgactgaa gagtatgggc
    28261 cttactatat cttgatgcca ggtatggcta tgccccacgc tagacctgaa gctggtgtgc
    28321 aaagtgatgc cttttcattg attaccttac aaaatcctgt tgtattttca gatgggaaag
    28381 aggtatctgt tttgttggca ctagcagcaa caagttcaaa aattcacaca agtgtagcca
    28441 ttccacaaat tattgccctg tttgaattag acgattctat tgcacgttta caggcttgcc
    28501 agactaaaga agatgtcttg gctatgattg aagaatctaa ggatagccct tatctcgaag
    28561 gattggattt ggaaagttag aaagaggaat aaagaaatga caaaaagaat acctaattta
    28621 caagttgcat tagaccattc agacttgcaa ggagcgatta aagcagctgt ttctgttggt
    28681 caggaagtag atattatcga agctggaact gtttgcttgc ttcaagttgg aagtgaactg
    28741 gctgaagtct tgcgtagcct tttcccagat aagattattg tggcagacac aaaatgtgct
    28801 gatgctggtg gaacagttgc taaaaataat gcggttcgtg gagcagactg gatgacttgt
    28861 atctgttgtg caaccatccc tactatggaa gcagctctaa aggctatcaa gactgaacga
    28921 ggagaacgag gcgaaatcca gatcgagctt tatggcgatt ggacttttga acaagctcag
    28981 ctttggctag atgcaggtat ctcacaagct atttatcacc aatctcgtga tgctcttctt
    29041 gctggtgaaa cttggggtga aaaagacctt aataaggtta aaaaactcat tgacatgggc
    29101 ttccgtgtat ctgtaacagg tggtctagat gtagatactc tcaaactctt tgaaggtgtt
    29161 gatgtcttta cctttatcgc aggtcgtgga attacagagg ctgcggatcc agcaggagca
    29221 gcgcgtgcct tcaaggatga aatcagacga atttgggggt aaatcatggt acgtccaatt
    29281 ggaatttatg aaaaggcaac cccaacacac tttacttggc tagaacgttt aaattttgcc
    29341 aaggagttag gctttgattt tgtcgagatg tctattgacg aacgtgacga gcgtttagca
    29401 agacttgact ggagtaagga agaacgcttg gaagttgtca aagcaatcta tgaaactggt
    29461 gttcgtattc cttctatctg tttttcaggc catcgtcgct acccattggg ttcaaaagat
    29521 ccagttctag aggaaaaatc tctagaactc atgaaaaaat gtatcgaatt agctcaagac
    29581 ttgggagttc gtacgattca attagctggt tacgatgttt actatgagga aaagtcaccc
    29641 cagacacgcc aacgttttat caaaaatttg agaaaagcct gtgactgggc tgaagaagct
    29701 caggtggtac ttgctattga aattatggat gatcctttca tcaatagcat cgaaaaatat
    29761 ttggctatag aaaaagagat tgactctccc ttcctctttg tatatccaga tattggtaat
    29821 gtgtctgcat ggcataatga tatctatagt gagttttatc ttggtcatca tgccatcgca
    29881 actctccatc tcaaggatac ttatgcagtg acagaaagtt caaagggcca gttccgagat
    29941 gtaccttttg ggcaaggttg tgtcaaatgg gaagaagctt tcgatatttt aaaggaaacc
    30001 aattataatg gacctttcct aatcgaaatg tggtctgaaa attgtgaaac agtagaagaa
    30061 acacgcgcag ccattcaaga ggcgcaagct tttctctatc cactcattaa gaaagcaggt
    30121 ttgatgtaag atgaatcaag taatcaatgc tatgcgtaaa cgagtctgtg atgccaatca
    30181 atcattgcca aaacatggac ttgtcaaatt tacctggggg aatgtatctg aagtcaatcg
    30241 cgaactcggt gtcattgtta tcaaaccatc aggcgtggat tatgacgaat tgacacctga
    30301 aaacatggta gtgactgatc tagatggtaa gatcctagaa ggggatttaa gaccatcttc
    30361 cgacttccca actcatgtgc aattatataa ggcttggtca gaaattggta gtgtggttca
    30421 cacccattcg acagaagctg ttgcttgggc tcaggcaggt cgtgatattc ctttctacgg
    30481 aacaacccat gcagattatt tctacggttc aatcccttgc gcccgtagtt tgaccaagga
    30541 cgaagtagaa gtggcctatg aaaaagatac tggcctggtt atcgtagaag agtttgaaca
    30601 tcgcggactt aacccggttg aagtaccagg aattgttgta cgcaatcacg gtccattcac
    30661 ctggggcaaa aatccagaga atgctgttta tcactctgtc gtactagagg aagtatcaaa
    30721 gatgaatcgc tttacagaac aaatcaatcc aagagttgaa cctgctcccc agtacatact
    30781 agaaaaacac taccaacgta aacatggacc aaatgcttat tatggtcaaa agtaagaacg
    30841 atgaaggagg agaaaaagat aaatttagct cctcttttta catttgattt ttattgagag
    30901 taaagttgga gttgaagtaa ttttgaaaga ttttttagaa atagcgcttg atatatatgg
    30961 taaaataaaa agaattgctg tgatatcaat agatttgggg gattttttaa tatggtactg
    31021 gataaggcaa gttgtgattt gcttcaatat ttgatggatc aagaaacgtc caaaacgatt
    31081 atggcgattt cgaaagattt gaaagagtca agaaggaaaa tttattatca cattgacaaa
    31141 atcaatgctg ctctggttga cgaggcgctt cacatcatta gtattccacg aattggtatt
    31201 cacttaacgg aagagcagag agatgcttgt tgtaaactat tatcggaagt agattcgtac
    31261 gattatatca tgagtgcgca tgaacgtatg atgataatgt tactatggat aggtatttct
    31321 aaagaacgta ttactattga aaaattgata gagttaacag aggtatctag gaatactgtt
    31381 ctcaatgatt tgaatagtat tcgttatcaa ctaactttgg aacaatatca ggtgaccttg
    31441 caagtgagca agtcacaggg ataccacctt catgcccacc ctcttaataa aattcagtat
    31501 cttcaatcgc ttctatatca tatttttatg gaagaaaatg ccacttttgt atctatttta
    31561 gaagataaga tgaaagagag gttagatgat gagtgtttgc tttctgttga aatgaaccaa
    31621 ttttttaagg aacaggttcc tttagttgaa caagatttag ggaagaaaat aaaccatcat
    31681 gaaataactt ttatgttgca ggttctacct tatttgctgt taagctgtca taatgttgaa
    31741 cagtatcaag aaagacatca ggatatagag aaagaatttt ctttgataag aaaaagaata
    31801 gagtatcagg tgtctaagaa attaggagaa cggttgtttc aaaagtttga aatttctttg
    31861 tcaggacttg aagtttctct tgtagctgtt ctcctcctct cctatcgtaa agatttggat
    31921 attcatgcag aaagtgatga ttttcggcaa ttaaaacttg ctttagaaga atttatctgg
    31981 tattttgaat cacaaatccg aatggagatt gagaacaagg atgatttgtt acgaaatttg
    32041 atgatccact gtaaagcctt gttatttaga aagacttacg gtattttttc taaaaatcct
    32101 ctaacaaaac aaattcgatc caagtatgga gaattatttt tagtcactag aaaatctgcg
    32161 gaaattttag aaggagcatg gtttattcgg ctaacagacg atgatattgc ctatttgacg
    32221 attcatattg gaggattttt aaagtataca ctatcgtctc aaaaaaatat gaaaaaagtt
    32281 tatctcgttt gtgatgaagg tgttgcggtt tcgagacttt tgctgaaaca atgcaaactt
    32341 tattttccaa atgagcaaat tgacactgta tttacaacag aacaatttaa gagtgtggaa
    32401 gatattgcac aagttgatgt agtgattact actaatgatg atttggatag cagatttccg
    32461 attttaaggg ttaatcctat ccttgaagca gaagatattt tgaaaatgct agactatctt
    32521 aaacacaata tatttcgtaa tgagagcaaa agtttcagtg aaaatctttc tagtcttatt
    32581 tcgtcttata ttgtagatag caagttggct agtaagttcc aagaagaggt tcaaacattt
    32641 ataaatcaag aaatagtagt tcaagctttt ttggaagata tttgaaggac agtccaatga
    32701 tgaacacaaa cctgtgtttt tcttggtctt ttttagtgtt ttgaagggtg gtatactaat
    32761 ctcaaagata acaattatat ccaaaggagg caacatatgc caaacgtcaa agaaattaca
    32821 agagagtcat ggattttagc cactttccca gagtggggaa catggttgaa cgaagaaatc
    32881 gaagaagaag tcgtacctga aggcaacttt gccatgtggt ggctaggcaa ctgtggtact
    32941 tggattaaga caccagctgg tgctaacgtt gtcatggacc tttggtcaaa ccgtggaaaa
    33001 tcaaccaaaa aagtgaaaga tatggttcgt gggcaccaaa tggcaaatat ggcaggtgtt
    33061 cgtaagctgc aaccaaactt gcgtgttcag ccaatggtta tcgatccatt tgctatcaac
    33121 gaactagact attacttagt ttcacacttc cacagtgatc atatcgaccc atacacagct
    33181 gcagcaattc tcaacaatcc taagttagag catgttaagt ttatcggtcc ttaccactgt
    33241 ggacgaatct gggaaggatg gggtgttcca aaagaacgta tcatcgttgt taaaccaggt
    33301 gacactatcg aattaaaaga tatgaagatt catgcagtag aatcatttga ccgtacttgc
    33361 ttggtaactc tcccagtgaa cggtgctgat gagacaggcg gtgaacttgc tggcttggct
    33421 gttacagatg aagaaatggc tcaaaaggct gttaactata tctttgaaac accaggtgga
    33481 accatctatc atggtgcaga ttctcacttc tcaaactatt ttgcaaaaca tggtaaagac
    33541 tttaaaattg atgttgcttt gaataactat ggtgaaaatc cggtaggtat ccaagacaaa
    33601 atgacatcta tcgaccttct tcgtatggca gaaaatctgc gtaccaaagt cattatccca
    33661 gttcactatg atatctggtc taacttcatg gcttctacta atgagattct agaactttgg
    33721 aaaatgcgaa aagatcgctt gcaatacgat ttccatccat ttatctggga agttggcggt
    33781 aagtacactt atcctcaaga tcaacactta gtagaatacc atcatccacg tggttttgat
    33841 gattgttttg aacaagactc taacattcaa tttaaagctt tgctataata taaaaatatt
    33901 ctttggaggt tatccgtatg ttgcatgata cggataattt tcatataata gtaaaataga
    33961 atgtgtgatt caataatcac ctcaaataga aaggaaattc tatgtcaaat ctatctgtta
    34021 atgcaattcg ttttctaggt attgacgcca ttaataaagc caactcaggt catccaggtg
    34081 tggttatggg agcggctccg atggcttaca gcctctttac aaaacaactt catatcaatc
    34141 cagctcaacc aaactggatt aaccgcgacc gctttattct ttcagcaggt catggttcaa
    34201 tgctccttta tgctcttctt cacctttctg gttttgaaga tgtcagcatg gatgagatta
    34261 agagcttccg tcaatggggt tcaaaaacac caggtcaccc agaatttggt catacggcag
    34321 ggattgatgc tacgacaggt cctctagggc aagggatttc aactgctact ggttttgccc
    34381 aagcagaacg tttcttggca gccaaatata accgtgaagg ctacaatatc tttgaccact
    34441 atacttacgt tatctgtgga gacggagact tgatggaagg tgtctcaagc gaggcagctt
    34501 catacgcagg cttgcaaaaa cttgataagt tggttgttct ttatgattca aatgatatca
    34561 acttggatgg tgagacaaag gattccttta cagaaagtgt tcgtgaccgt tacaatgcct
    34621 acggttggca tactgccttg gttgaaaatg gaacagactt ggaagccatc catgctgcta
    34681 tcgaaacagc aaaagcttca ggcaagccat ctttgattga agtgaagacg gttattggat
    34741 acggttctcc aaacaaacaa ggaactaatg ctgtacacgg cgcccctctt ggagcagatg
    34801 aaactgcatc aactcgccaa gccctcggtt gggactacga accatttgaa attccagaac
    34861 aagtatatgc tgatttcaaa gaacatgttg cagaccgtgg cgcatcagct tatcaagctt
    34921 ggactaaatt agttgcagat tataaagaag ctcatccaga actggctgca gaagtagagg
    34981 ccatcatcga cggacgtgat ccagtcgaag tgactccagc agacttccca gctttagaaa
    35041 atggtttttc tcaagcaact cgtaattcaa gtcaagatgc cttgaatgtt gtggcagcta
    35101 aattaccaac cttcctaggt ggatcagctg accttgctca ctcaaacatg acttatatca
    35161 agacggatgg acttcaagac gataccaatc gcttgaatcg taacattcag tttggtgttc
    35221 gtgaatttgc aatgggaaca atcttgaacg ggatggccct tcatggtgga cttcgtgtat
    35281 acggtggaac tttcttcgtc ttctctgact atgtgaaggc agctgtccgc ttgtcagcct
    35341 tacaaggact tcctgtgact tatgtcttta cccatgattc aatcgcagtt ggggaagatg
    35401 gtccgactca cgaaccagtt gagcatttag caggtcttcg tgctatgcca aatctaaatg
    35461 ttttccgtcc agcagatgcg cgtgaaacgc aagcagcttg gtaccttgca gtgacaagtg
    35521 agaaaacacc aactgccctt gtcttgacac gtcaaaactt gactgttgaa gatggaacag
    35581 acttcgacaa ggttgctaaa ggtgcttatg ttgtatatga aaatgcagcc gactttgata
    35641 ccatcttgat tgcgacaggt tcagaggtca atctagctgt cgcagctgcc aaagaattag
    35701 ctagtaaagg cgaaaaagtc cgcgtagtca gcatgccatc tacagatgtc tttgataaac
    35761 aagatgcagc ttacaaggaa gagattcttc caaatgcagt ccgccgtcgt gttgcagtcg
    35821 aaatgggtgc aagtcaaaac tggtacaaat atgttggtct cgatggtgcc gttctaggta
    35881 ttgatacctt cggagcctct gccccagcac caaaagtatt ggcagaatat ggctttactg
    35941 tagaaaatct tgtaaaagtt gttcgaaact tgaaacaatc ctaaaaatca gggcgtaagc
    36001 tctggttttt cttaccagaa aagtaaggta caatcttgta aaagtagctg aaatttgata
    36061 tagtagtcct atgtaaaaga caaaggagaa aacaatgaat ccaaatatta cttttttaat
    36121 catgcttgta ggtatgatgg ccttgatgtt ctttatgcaa cgctctcaaa agaaacaagc
    36181 acaaaaacgt atggaaagct taaataaact acaaaaaggc tatgaagtga ttacaatcgg
    36241 tggactttat ggaacagtcg atgaagtaga tacggagaag ggaacaatag ttcttgacgt
    36301 agatggagtt tacttgactt ttgaactagc tgctatcaag acagtattac cgctgaaaga
    36361 aacagcttca ctagaaggcg caattgaaaa ataagacggg atcacgaact cccgtttttc
    36421 tataaaagaa aggaaatggg atgaaaaaat tagtctttgt ctgtctggga aatatttgcc
    36481 gtagccctat ggccgagttt gttatgaaat caatgacaga taactacgaa atccaaagtc
    36541 gagcaacttc ctcttgggaa catggcaatc cgattcataa ggggactcag ggaatttttc
    36601 aagagtatga gattccttat gacaagaaca agacatcgct tcagattagt aaggaagatt
    36661 ttgaagcctt tgattatatt atcggaatgg acgcttcaaa tgtttccgac ttacgtcaga
    36721 tgtgtccagt agactgtcaa gataagattt actcattttc atctgaaagt gttccagacc
    36781 cttggtatac aggagatttt gaagaaacct atcgacgtgt tcaagagggc tgtcaagctt
    36841 ggttagaacg tttagaaaag gagagttaag gtggaaaatc ttacgaattt ttacgaaaag
    36901 tatcgtgtct atctgactcg tccacgttta gagcttttgg cagtagttac cattgttttc
    36961 tgtgctgtac tcgtcttttt tctaaatatt ccaggaaaag gtgtcttaaa actcgataat
    37021 ggaacgattg tttatgatgg cagtcttgtc cgtggtaaaa tgaatggcca aggtaccatt
    37081 accttccaaa atggagacca atatacaggt ggcttcaaca atggagcctt caacggaaaa
    37141 ggtacctttc aatctaaaga aggctggacc tacgaaggtg attttgtaaa tggtcaggct
    37201 gaaggaaaag ggaaactaac aacagaacaa gaagtcgttt atgaaggaac ttttaaacaa
    37261 ggcgtttttc aacaaaaata aagcctcctt atcaaaggag gtattattag aattacaagg
    37321 taagcgttta cctgtaaatc cctttctttc caaatccctc ttccaagcaa gtttgtgaaa
    37381 taaaaaatat ttgaaataaa tttcacaaac ttcaaagata aaacctgata agaaaagaaa
    37441 atgagaaaag tttcacaaga gtttaaaatt ctttgtgaaa tgtttatgaa actgtttaca
    37501 aagttgaaat aatgcgttat aataaacttg tgaaaaaatt aacaaaggat atcgttcctt
    37561 gaaagctatg gaggaaaata tggctgataa aaaaactgtg acaccagagg aaaagaaact
    37621 cgttgctgaa aaacacgtag atgagttggt tcaaaaagct ctagttgccc ttgaagaaat
    37681 gcgtaaattg gatcaagagc aagttgacta catcgttgcc aaagcatcag tagcagcttt
    37741 ggatgcccac ggagaattgg ctttacatgc ctttgaagaa acaggacgtg gtgtatttga
    37801 agataaagca actaagaact tgtttgcctg tgaacacgta gtaaacaaca tgcgccacac
    37861 taagacagtt ggcgttatcg aagaagacga tgtaacagga ttgactctta ttgctgaacc
    37921 agttggtgtt gtttgtggta ttactccaac aacaaaccca acatcaacag caatcttcaa
    37981 atcattgatt tcattgaaga cacgtaaccc aatcgtcttt gccttccatc catcagcaca
    38041 agaatcatct gctcatgcag ctcgtatcgt ccgcgatgca gctatcgcag ctggtgctcc
    38101 tgaaaactgt gtgcaatgga ttactcaacc atctatggaa gcaacaagtg cccttatgaa
    38161 ccacgaaggt gttgcgacaa tccttgcaac aggtggtaat gccatggtta aggcggctta
    38221 ttcatgtggt aaaccagctc ttggggtagg tgccggaaac gttccagctt atgttgaaaa
    38281 atcagcaaac attcgtcaag cagcacacga tatcgtcatg tctaaatcat ttgataacgg
    38341 tatggtctgt gcatctgaac aagcagttat cattgataaa gaaatttacg atgaatttgt
    38401 agcagagttc aaatcttacc acacttactt tgtaaacaaa aaagaaaaag ctcttcttga
    38461 agagttctgc ttcggcgtca aagcaaacag caaaaactgt gctggtgcaa aattgaacgc
    38521 tgacatcgtt ggtaaaccag caacttggat tgcagaacaa gcaggattta cagttccaga
    38581 aggaacaaac attcttgctg cagaatgtaa agaagttggc gaaaatgagc cattgactcg
    38641 tgaaaaattg tcaccagtta ttgcagtttt gaaatctgaa agccgtgaag atggtattac
    38701 taaggctcgt caaatggttg aatttaacgg tcttggacac tcagcagcta tccacacagc
    38761 tgacgaagaa ttgactaaag aatttggtaa agctgttaaa gctattcgtg ttatctgtaa
    38821 ctcaccttct acttttggtg gtatcgggga cgtttacaat gccttcttgc catcattgac
    38881 acttggatgt ggttcttacg gacgcaactc agttggggat aacgttagtg ccattaacct
    38941 cttgaatatc aaaaaagtcg gaagacggag aaataacatg caatggatga aacttccttc
    39001 aaaaacatac tttgaacgtg attcaattca ataccttcaa aaatgtcgtg acgttgaacg
    39061 tgtcatgatc gttactgacc atgccatggt agagcttggt ttccttgatc gtatcatcga
    39121 acaactggac cttcgtcgca ataaggttgt ttaccaaatc tttgcggatg tagaaccgga
    39181 tccagatatc acaactgtaa accgtggtac tgagattatg cgtgccttca aaccagatac
    39241 catcatcgca ctcggtggtg ggtctccaat ggatgctgcc aaagtaatgt ggctcttcta
    39301 cgagcaacca gaagtggact tccgtgacct tgtccaaaaa ttcatggata tccgtaaacg
    39361 tgccttcaag ttcccattgc ttggtaagaa gactaaattc atcgcgattc caactacatc
    39421 tggtacagga tctgaagtaa caccatttgc cgttatctct gataaagcaa acaaccgtaa
    39481 atacccaatc gctgactact cattgacacc aactgtggca atcgtagatc ctgctttggt
    39541 attgacagtt ccaggatttg ttgctgctga tactggtatg gacgtattga ctcacgcgac
    39601 agaagcatac gtatcacaaa tggctagtga ctacactgat ggtttagcac ttcaagccat
    39661 taaattggtc tttgaaaatc tcgaaagctc agttaagaat gctgacttcc actcacgtga
    39721 gaaaatgcat aacgcttcaa caatcgctgg tatggccttt gccaatgcct tcctaggtat
    39781 ttctcactca atggcccata agattggtgc gcaattccac acaatccacg gtcgtacaaa
    39841 tgctatcttg cttccatacg ttatccgtta caacggtaca cgtccagcta agacagcaac
    39901 atggcctaag tacaactact accgtgcaga tgaaaaatac caagatatcg cacgcatgct
    39961 tggacttcca gcttctactc cagaagaagg ggttgaatct tacgcaaaag ctgtctacga
    40021 actcggtgaa cgtattggga tccaaatgaa ttttagagac caaggaattg acgaaaaaga
    40081 atggaaagaa cattctcgtg aattagcctt cctggcttat gaagaccaat gttcaccagc
    40141 taacccacgt cttccaatgg tagaccatat gcaagaaatc atcgaagatg catactatgg
    40201 ctacaaagaa agaccaggac gccgtaaata attgtttatc agtctagaag caagacaaaa
    40261 actcaatttg agggaaagat ccagtaattt ttctatgata aaaggcatcc tatcaaggtt
    40321 tttgaacacc tgataggatg cttttttatg atattgaggc ctttttgccc tttttgaaaa
    40381 actagaatag aaacaaaata tgtaatagat tgaaactaga atagtacaca tctgcttcta
    40441 aaacatttat agaaattaat tttactttcc tgatagagtt gttcacatct tatttcaatt
    40501 cactatagtt taatttaaga gtagtattta ctaaggccca attaaaatca aagagcaaac
    40561 tagaaaacga gtgccattca gctcaaaaca ctgatttgag attgcagata agactagccc
    40621 cctcattaac agatttacga taaaacgatg acaaggtgtg ttgctttttg atttctaaag
    40681 agtataatga tagatctcta taaaataagt gcgaaggaaa tgagctttta tagtcctttc
    40741 gttttaaaat actatctcag atattcttat atcgacaaga agtttttgag tcattccctc
    40801 atcatacata ttaaataaat agtggctcat tcaatttttc actagaataa taagctagta
    40861 tagtaaactg aaataagata taaacaaata aattggagct taacatccat ttccagcaat
    40921 tttttagaaa ctacagtgga ctattctaga ttcaacatat tataaaaact agagtaaaag
    40981 aaaaggattg gatcttgtgt aatgcaggat ccaatccttt caatcatttt gtccaacttt
    41041 tggaggttcc tacaatgtag tcgtcattaa taaagacaga tgggaatgac agtgttccta
    41101 tttattttga tagagatcga tgaattcttt agatagcaac tgaataatct ctgttgaagc
    41161 catttggtct tctgcatgca taaatagcaa ggagaatcct attttttctc cagtagcttc
    41221 tttttgtatg agattagagt gaatcttgtg cgcttctact aaggagtctt ccgcttcttc
    41281 aactttaatt ttcgcttctt ttaaatttcc tgccttagct agttggatgg cttcaataaa
    41341 ggatgatttg gctgctccac tattggcaat gagctgaaaa cagatatatt ccatttcttc
    41401 tgtcatctta tttctcctat ccattcaagt gcttgttcca gaacttttgc tccattcatc
    41461 attccgtaat cccgcatatc aatggtatct acagggatat ttcctgcaat ttctttcaca
    41521 gcaagtaact cataacgaat ttgtggccca attagaatga catctgcttc atggatattc
    41581 tttttagctt ctgtcattga ttttgcttgg atagaaattt caatcccacg ttcagtcgca
    41641 ctttgttgca tttttttaac aagcatactt gtcgacattc ccgcattaca tactaataaa
    41701 atttgtttca taatcttaac cttccatttc ttgttcaaca actttgtcat taactttgat
    41761 aaatggaatg tatagaagaa ctccaagtgc aaagatgatg aattgaacta gaactgctct
    41821 cacgtcccct gctgttgcta accatgcatt taagaatact ggtgtagtcc aaggaacttg
    41881 tataaatgca ggactcatga atcctgtaac tgttgctaag tagctgatta aaataccaag
    41941 gactggaact gtgataaatg gaatagctaa tgaaatgtta taaacgattg ggtaaccgaa
    42001 taatactggt tcattgatat tgaagatacc aggtccaaaa gataatttag ccacgttttt
    42061 agaaacagca ttgcgactta ctaagaatgt tgctattaat aaacataatg tagatccact
    42121 accacccatt aaagcgaatg tttgtatttg tgataggttg atgatgtgtg gaatggcttg
    42181 tccattattt gctgcagtga tgttttcagt aatgttaatt aatagtaatg gttctaggat
    42241 ggcactgtaa ataactgctt ggtgaatacc aaatagccat aacatatttc ctaaagagta
    42301 aataataatg accccgatta agcttgtacc aatatgacga attggttctt gaataaagat
    42361 tgtaatgatt gagattaagt tcattccagt tatattgaat aataatgctg aaacaacccc
    42421 aaataaggag atgacggtca tgactggaag taatacgcta aatgatctac taacagctgg
    42481 tggaatattt tcaccaaggt tcatttgtaa agctttaaca tttgataatt caatgaataa
    42541 ttctgttgca ataatcgcta cgataacccc ggcgaacatt gcgcctgtac ctgtgttgtt
    42601 gaatgaaaga acacctgaaa tgtttacagc atcttttgct ccgtcaggaa ctacagaaac
    42661 tgtatttggc atcatcacaa ttaaagaaac taatgatagc attgatgctg ctaacgggtt
    42721 ttcgaaatct ctgtttttag ctaagaaata accaaccatt acagcaataa tcatacctga
    42781 aatacttaaa gtaccgtttg caattgttat tccccaatat tggaatcttg ttaatgtatc
    42841 cccttggaaa atccacttaa ataccgtgtt gttcaaaaga acgattaaac ctgccaaaat
    42901 atataatggc attactgtta cgaatgcatc tcttagagtt tttaaatgaa tttggttccc
    42961 tagtttacca gcaaaggtgg caaattgatc tataaatttt gagtttttca tctgaatatc
    43021 tcctctcttt actcctcaat ttctacttca aaaccgttat tgtcacttac tttgcgatac
    43081 catcttcctg agctcttgat ggttctcttt tgcgtttcta aatcaacgga gataaatccg
    43141 taacgattct tatatgcatt attccaagac cagcaatcaa atgcggtcca agcgtggtat
    43201 ccaaaacagt gacttccctc ttcaatggct ttatgtagcc atcttaaatg ttcttcataa
    43261 aattcaatac gatacacgtc atcgataact ccattttcac cgataaaccg tgcttcgttt
    43321 tcaacaccca ttccgttttc actgataaac catggaatat tatcatattc ttccttcaca
    43381 atcatagcaa tatcataaat ggctttcgga aaaatttccc aaccacgata tggattcatg
    43441 cgacgctccg gccattcata ctctttgaag tattggtctg gcatccaggg cgtctgatat
    43501 tcctcaggat ttgcttgtgc ttgaacacgt tttggatggt agtagtttac tccaagaaaa
    43561 tcaaccgtat ttgatttcat cagttgaagc tctttttcgg tatgactcca taacacgcca
    43621 tctctctcta gctgttttac caatctttct gggaaagttc ctttaacagc tggattcaag
    43681 aagactttgt taaagaagtc atctgtaaat cgacttgctt ctaagtcttc tggagaatta
    43741 cttcttggat aagcaggtgt caagtttaaa ataatcccaa tctttccatc aagtcctaat
    43801 gagcgatata gttgaatcac ttttgcacta gcaaggttta gattatagat gacttgtacg
    43861 gcctcttttc cctttccttt tagatttgga taatggaaag catataagta tcctgcttct
    43921 ggaatgacca ttggctcatt gaaagttgtc cagtaatgaa ccttatctcc aaagcatgtt
    43981 aaagcagtct tggcaaactt cacgaataac tccactacat gtttgctttc ccaaccaccg
    44041 tatttttgaa gaagttccac tggtaaatca aaatgatgta aattcatcac aagatccatc
    44101 tggttctttt tagcttcttc aatgatggca ttgtagaaag caataccttt tggatcaggc
    44161 tcacctgtct ctaaattctt gatgagtcga ctccattgga tggaagtgcg gaaagaatta
    44221 actccaattt ccttcatcaa gtggaaatct tcggtgtaag tatgaaaaaa gttactggct
    44281 acaagaggtc cgacattatc gaaaaaatct tctggatgcg ttttgaacca gtagtccatc
    44341 acattttcat gtacttttcc atattgacct tctgtctgag gtccgctaga agcagctccc
    44401 caccaaaaca gattaggaaa tactaacttt tttttcatgc tcaacctcct ttctattatt
    44461 ctatacataa agtatagcat aattttaaaa tttgtctaga catttttaaa aattgttgat
    44521 acatatcttg tgtttgcctc atttcttgaa ctttgttata ctactattag aatattatag
    44581 agagaaccag attaaatgag tacaaaatat ttatttattt acaatgagat tcgtgaaaag
    44641 attctttgta ataaatatac catgaacgaa caattgcctg atgaaatgac attagctaaa
    44701 cagtttgcct gtagtcgaat gacgatcaaa aaagctttag acttgttagt ttctgagggc
    44761 ttaattttta gaaaacgtgg gcagggaacc tttgttctct ctcgtggcag ctcaaaaaga
    44821 aaattaatcg ttccagaaag agatatccgg ggactgacaa aaatatctga agatgctcat
    44881 tctacaattg actcgaggat tattcacttc aaattagaat ttgcaaatga atttttagca
    44941 gaaaaactac aggtcgcttt gcagagtcca gtttataata tttaccgcct gcgtattatt
    45001 gacggtaaac cttatgttct ggaacaaact tatatgagta ccgatgttat tccaggtatt
    45061 actgaagata ttttacaaaa atcgatttac aattacattg aaggaaaatt aggattgcat
    45121 attgccagtg ctacaaaaat cttacgagct tcttctagtt cagaaaatga gcaacattac
    45181 ttgcagctcc ttccaacgga accggtattt gaagtagaac aagtggctta tttggataac
    45241 ggaactccgt ttgagtactc gattagtcgt catcgctatg atttatttga atttaattct
    45301 tttgcattac gacattcctc ctaggagaaa atgtgaaaat gaagccaatc ttttacagac
    45361 tctagtttaa gaaaaattta aaacagggca agaaggtccc atctatgctt aaatggtttc
    45421 tcttttctaa ataagatggc tttaaaagag tgatcgtttt atccatcatg ttgaaaaata
    45481 tcttcgtata gcttatagag taggtactga aattgttcgc ctgatctact tcttatagtt
    45541 atttagtttt aaatagtgtt tcaaacattc ttacactgac gagaagtttt tgagtctttt
    45601 cttgtaacac atatagtata ctgaggttag aatagtagac tgtgacttct aacaaattgc
    45661 tagaaatgaa tttcaatctc ccaatttatt tgttcatatc ttcttttaat atattaaata
    45721 aattctgaat cataatcatt taaaaaaatt ttattttttt atttttcatt acgaataata
    45781 tagatgaagg ggaaagagta tgaaaacaga actgtttctt ttgctattag ttcaaaagga
    45841 gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtatatt gtttgataat
    45901 atttcttttg atacttcgag ttcaggcgtg acattaatta ctggtaaaaa tggtacagga
    45961 aagtcaactt tactatagta gattgaaact agaatagtac acatctactt ctaaaatatt
    46021 gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca tttcactata
    46081 tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt tcttcatatt
    46141 tttcatattc ttgaatccat cgataaagac tattgggatg aatttttaaa gttgaactaa
    46201 tcatttttac aggatgaggt ttacagcaga gagtttgaag gctttatcaa aggtttttct
    46261 tggcataatg acttttcctc gtttccactt aattttgtgt ctactttatt ataccaagtc
    46321 cacccttaag ttagataata aatctaactt aaggaagcta gaaggatgag aatccaggtg
    46381 gtcaagagtc ccaaacttaa gctgatgggg acacccagaa taatttgctt tttgaaggca
    46441 aggccacgtt cctctatatt gggaagtgag agttgaatga gagaaccagc tgatgaaaag
    46501 ggtgagatat tagtagatag agcgccaata acggtggctg ttgtgagtaa gtgaatatca
    46561 atctggggat tttgagcact gatgatagca atgatgggaa agagggctgg agctacaacg
    46621 gatagggtgg aactaaagag tgacatcact ccggctatca cacaaaagaa cagaggtaac
    46681 cagaaatgag gaatggatgt tgtcatgagg tgccctatca gtgtgactaa acctgacttg
    46741 accgctagag acattagtaa gctcatgccg cagagcatga taattgtagc ccagggaact
    46801 ttagccaaaa tggcttcttg cttccctaat ttgagcctta aggcgaggca gaccatgagt
    46861 attgagacaa agccaatatc aaatgttttt cgataagtag ctatccaggc gatgtttggg
    46921 aaaatgagat gcaacaaggg aaaaagccaa accaaaacca tgctgctgat catgagtaag
    46981 gtggtttgtc tttgaacctt gctgaggagt ggtggttggt caatagtcaa ggatgagttt
    47041 gttcttccct tgctatagtg actgtaacag gataataaaa gcaagacgat gagtgggtag
    47101 ataatgctga cgataaagat atgattgcca agtgaaaaag cttgctcttc ccatcccatt
    47161 tgcttaaaca ggccttgaaa gacaatgcct gagctactgg ttatcaaatt agcccctcct
    47221 gaagctcccc aattgacggc ttgagctcca atcaaagggt gtttgtccgc tttttgacag
    47281 agggtaatcg ctagaggaca gcaaacggcc atagtagtga aaaatccagc acctaaagca
    47341 gacaaaaggg ttgccatcag gtataaaatc atgtagaggg cgttagggta ggtgcgtgtg
    47401 cggtagagaa tgtgttgagc caaaacatca agagtaccgt tagttattgc aaagttataa
    47461 aagagagaga cgctaaaaat ggtaaaaaag agtgaggttg gccaaaaatg aagaagttct
    47521 ttggggctta atcccatgag agtggttgcg atgaggtaag aaaaagcaat agccagcagg
    47581 ccaatattga ttttggtgcg gtaaccaatt ccaatggcta gagcaatggc gctaatcatt
    47641 attaaatgaa tcattgaatt gtcctttcag ttagaatatg gaaataggtt ggcaattttg
    47701 gcgctcaaaa gaccacctgt ttcctattgg tacttgacta ttatacacaa aaaaaataca
    47761 attgtcttga caattgtatt gacaattgtt agaattaaaa atgaggtatt caggcttgtg
    47821 attttctatg gaagttaata gtgattgcct ctaatgctta caagtgatat taaaaataga
    47881 ggacctagtg atgtcaatca tttcaactga tttaacccct tttcaaatag atgatacatt
    47941 gaaagcagcc ttgcgagaag atgttcattc cgaagattac agtaccaatg ccatttttga
    48001 tcatcatggc caagccaagg tgtcgctttt tgccaaggaa gctggtgttt tagcggggct
    48061 aaccgttttt caaagggttt ttaccctatt tgatgccgag gtgaccttcc agaatcctca
    48121 tcaatttaag gatggggatc gtttgactag tggcgatttg gttttagaaa tcataggctc
    48181 ggtgagaagt ctcttaacat gtgaacgcgt tgccttgaat tttttacaac atttatcagg
    48241 gatcgcttcg atgacagctg cttatgtaga agccttaggc gatgattgca ttaaggtatt
    48301 tgatactcga aaaactactc ctaatttacg tctttttgag aaatatgccg tgagagttgg
    48361 cggtggctat aatcatcgct ttaatttatc agatgctatc ctgctaaaag acaatcacat
    48421 tgcggcagta ggtagtgttc aaagggcaat tgctcaagcg cgtgcctatg ctccttttgt
    48481 gaaaatggtc gaggtggaag tggaaagcct tgctgctgcc gaagaagctg cggcggcggg
    48541 tgctgatatt atcatgttgg ataatatgtc attggaacag attgaacagg ccattaccct
    48601 aattgcagga cgttctcgga ttgaatgttc tggaaatatt gatatgacca ctattagccg
    48661 ttttcgtggt ttagcgattg attacgtctc cagtggtagt ttaacccata gtgctaagag
    48721 tcttgatttt tccatgaagg gtttaaccta ccttgatgtc taagttgtaa aataaactaa
    48781 ctttttaaag gatgtctttc ctctagaacg agttttatgt cagatagttt aaacgcctct
    48841 tcaaatatag taaaatgaac caaaaatagt acacaatgtg gtataatctt cttatggcat
    48901 attcaataga ttttcgtaaa aaagttcttt cttattgtga gcgaacaggt agtataacag
    48961 aagcatcaca cgttttccaa atctcacgta ataccattta tggctggtta aagctaaaag
    49021 agaaaacagg agagctaaac caccaagtaa aaggaacaaa accaagaaag gttgatagag
    49081 atagacttaa aaactatctt actgacaatc cagacgctta tttgactgaa atagcttctg
    49141 aatttggctg tcatccaact accatccact atgcgctcaa agctatgggc tacactcgaa
    49201 aaaaagaacc acacctacta tgaacaagac ccagaaaaag tagccttatt tcttaaaaat
    49261 tttaatagtt taaagcacct agcacctgtt tagattgatg aaacaggatt cgatacttat
    49321 ttttatcgag aatatggtcg ctcattaaaa ggtcagttaa taagaggtaa agtatctgga
    49381 agaagatatc agaggatttc tttggttgca ggtctaacaa atggtgagtt aatcgctcca
    49441 atgacttacg aagagacgat gacgagcgac ttttttgaag catggtttca gaagtttctc
    49501 ttaccaacat taaccacacc atcggttatt attatggata atgcaagatt ccatagaatg
    49561 ggtaagttag aacttttatg cgaggagttt gggcataaac ttttacctct tcctccctac
    49621 tcacctgagt acaatcctat tgagaaaaca tgggctcata tcaaaaagca cctcaaaaag
    49681 gtattaccaa gttgcaatac cttttatgag gctcttttgt cctgctcttg tttcaattga
    49741 ctatagttca cggatacagt tgggaaagaa gctattaaat atttggagag tccttttggg
    49801 atgaacatgt caaatattac tatagatggg caagaaaaga tgggcaagaa atggatttga
    49861 gtcaaacgat gcttcttatg ctcaagtagt gagtctttat gatgatacaa gtatctctgt
    49921 tagtaataat gagacggaca aagtgttggc tggatccctc tatactgata caaatgaaca
    49981 gggattaacg attccaagca gtttactaaa aaattggaat gaacagacag gaaaaaattt
    50041 gacagctaat gatcttattg gcaaatcagt ctcagtcagc attgtagaaa gtgctgccga
    50101 aactagtaag attgctcaat ttcaaacgaa gattgtacgt gtaatcaatg atgaagatga
    50161 catggaggac agcaacagtt tcatgctgtc tcatcaaatg gaaacgattt tgaaagaggc
    50221 tggatttacg aaagctgtat cttattttat cttggaactc aaagatccat cacagacaaa
    50281 agtagtaaca gaagaattac agaaaaataa gaagtatact gtgctttctt aacagagagt
    50341 tcttgatatt gtgattacct ttattcgtgt tattcaggga ttattgattg tgctttcatc
    50401 acaagctatt gtggtagcag cggttatgat tggtatcatt atttacatca atatcatgca
    50461 acgttccaag gaaataggtg tcatgaaagc agttggttat cagaatcgtg atgtcaaagg
    50521 aatttttatt tacgaggcta tctggattgt aggcatcgcc ttgctgctgg catttttggt
    50581 tgcacaaggg gtgggaagtt tggcgaatgc gattgtaagt cacttttacc catccatcac
    50641 taaggttttt gaattaaatc ttttatctgt tttaggaact ctagttttcg ctctattact
    50701 tggttatgtc tcagcctact tcccggcgcg taagattagt aaaatggatc ctgtagaatc
    50761 gttacgctat gaatagtaag ggattccttg atttacagtc ttaaaaagaa actaacatag
    50821 aaaaacaatg gccatacttg caattcaact caaatagttg tataataggt ttgttgaaag
    50881 gtgatttgta gtgattcaag ttactctttt cacaataaaa atttcatgat tttcataagg
    50941 aggaaatcac taatggtagt taaagttggt attaacggtt tcggacgtat cggtcgtctt
    51001 gctttccgtc gtatccaaaa cgtagaaggt gttgaagtta cacgcatcaa cgaccttaca
    51061 gatccagtta tgcttgcaca cttgttgaaa tacgacacaa ctcaaggtcg tttcgacggt
    51121 actgttgaag ttaaagaagg tggatttgaa gttaacggta aattcatcaa agtttctgct
    51181 gaacgtgatc cagaacaaat cgactgggct actgacggtg tagaaatcgt tcttgaagct
    51241 actggtttct ttgctaagaa agaagcagct gaaaaacacc ttaaaggtgg agctaaaaaa
    51301 gttgttatca ctgctcctgg tggaaacgac gttaaaacag ttgtattcaa cactaaccac
    51361 gacgttcttg acggtactga aacagttatc tcaggtgctt catgtactac aaactgcttg
    51421 gctccaatgg ctaaagctct tcaagacaac tttggtgttg ttgaaggatt gatgactact
    51481 atccacgctt acactggtga ccaaatgatc cttgacggac cacaccgtgg tggtgacctt
    51541 cgccgtgctc gcgctggtgc tgcaaacatc gttcctaact caactggtgc tgcaaaagct
    51601 atcggtcttg taatcccaga attgaatggt aaacttgatg gatctgcaca acgcgttcca
    51661 actccaactg gatcagttac tgaattggta gcagttcttg aaaagaacgt tactgttgat
    51721 gaagtgaacg cagctatgaa agcagcttca aacgaatcat acggttacac agaagatcca
    51781 atcgtatctt cagatatcgt aggtatgtct tacggttcat tgtttgacgc aactcaaact
    51841 aaagttcttg acgttgacgg taaacaattg gttaaagttg tatcatggta cgacaacgaa
    51901 atgtcataca ctgcacaact tgttcgtact cttgaatact tcgcaaagat tgctaaataa
    51961 ttcttgagtt gatagaaagc aaggctttgt ggtcttgctt ttttatatgg aaaaatggat
    52021 gacacgatca tccattcttt tttaattctt tttcaaatgt atttgaaagg gtagtgaaag
    52081 ttagcttctc taaagtaagt gggtgggtaa aggaaagtcg gaaggcatga agcataagcc
    52141 gacttgtctt tgatttacta ttatagagag ggtcgcccag gataggaaga ttatgatgcg
    52201 aaaggtgcac acgaatctga tgggttcgcc ctgtctttag cttgcaacga gccaaggaag
    52261 tcttgtttga gaattgcttt aatctgctta catgcgtttc agcatattgc ccattttttg
    52321 catcaactat tctttttcta cgatcatggc gatcacgtcc aattttgtct ctgaaaacaa
    52381 gttcttttct gttgatattt ccatcaacta gagcccaata ttctctagaa atctcttttt
    52441 tctccaataa gcgattgaga atgggcagga taaaaggatt tttggcaaag agaactaagc
    52501 cactggtttc catgtccaga cgatgaacga catagcaggt ttggccaaca taggtactga
    52561 catggttaag aagggcaatt tcgtttggtt gattaccatg cgttttcatc ccctctggtt
    52621 tgtttacaat aatcaagtgt tgatcttgat aaacttcctg cactaagtct gggttgcccc
    52681 aagggatcgt cttttgggga taatcttcct cgtcaaaagt caactggcaa acatctccag
    52741 gatttacgat ttccttccag tggacttctt cttgatttat caaaatatgt ttcttgattc
    52801 tcaaaaaatg acggattttt ctagggatga ggagttgttc ctcaagtaat tgctttaccg
    52861 tcatttgagg tagagaggcg ggtaatgtaa atgtgaattg catacagata ttgtaacaaa
    52921 aaaagcccta tttggatagg aaatagctaa attcttgtct tcctatgatg aagatgataa
    52981 aataaacgca tgaaattaga taaattattt gagaaatttc tttctctttt taaaaaagaa
    53041 acaagtgaac tagaggactc tgattctact atcttacgtc gctctcgtag tgatcgaaaa
    53101 aaattagccc aagtaggtcc gattcgaaaa ttctggcgtc gttatcatct aacaaagatt
    53161 atccttatac taggtttgag tgcaggcttg ctagttggaa tctatttgtt tgctgtagcc
    53221 aagtcgacca atgtcaatga tttgcaaaat gccttgaaaa ctcggactct tatttttgat
    53281 cgtgaagaaa aagaggctgg tgccttgtct ggtcaaaagg gaacctatgt tgagctgact
    53341 gatatcagta aaaacttgca gaatgctgtt attgcgacag aagaccgttc tttctataaa
    53401 aatgacggga ttaactatgg ccgtttcttc ttggctattg tcactgctgg acgttcaggt
    53461 ggtggctcta ccattaccca acagctggct aaaaacgcct atttatcaca agatcaaact
    53521 gttgagagaa aagcgaaaga atttttcctt gccttagaat taagcaaaaa atatagtaag
    53581 gagcaaattc taaccatgta ccttaacaac gcttattttg gaaatggtgt gtggggtgta
    53641 gaagatgcga gtaagaaata ctttggagtt tctgcatcag aagtgagtct ggatcaagct
    53701 gcgactctgg cagggatgct caaggggccg gaactgtata atcccttgaa ttccgtagaa
    53761 gattctacta atcggcgcga tactgtcttg cagaatatgg ttgcagcagg atatattgat
    53821 aaaaaccaag aaaccgaagc tgctgaagtt gatatgactt cgcaattgca cgataagtat
    53881 gaaggaaaaa tctcagatta ccgttacccc tcttattttg atgcggtggt taatgaagct
    53941 gtttccaagt ataatctaac agaggaagag attgtcaata atggctaccg catttacaca
    54001 gagctggacc aaaactacca agcaaatatg cagattgttt atgaaaacac atcgctattt
    54061 ccgagggcag aggatggaac gtttgctcaa tcaggaagtg tagctctcga accgaaaaca
    54121 gggggagttc gtggagttgt cggtcaagtt gctgacaatg ataaaactgg attccggaat
    54181 ttcaactatg caacccaatc aaagcgtagt cctggttcta caattaagcc tttagttgtt
    54241 tatacgccag cagttgaagc aggctgggct ttgaataagc agttggataa ccataccatg
    54301 cagtatgaca gctataaggt tgataactat gcagggatca aaacgagtcg agaagttcct
    54361 atgtatcaag ccttggcaga atcgcttaat ctacctgctg ttgccactgt taatgatttg
    54421 ggtgtcgaca aggcttttga ggcaggcgaa aaattcggac tcaacatgga aaaggtcgac
    54481 cgtgttcttg gtgtcgcctt gggaagcggt gttgaaacca accctcttca aatggctcaa
    54541 gcatacgctg cctttgcaaa tgaaggttta atgcctgaag ctcattttat tagtagaatt
    54601 gaaaatgcta gtggacaagt tattgcgagt cataaaaatt cacaaaaacg ggtgattgat
    54661 aagtctgtag ctgacaagat gaccagtatg atgttgggga ctttcaccaa cggtaccggt
    54721 attagttcat cgcctgcaga ctatattatg gcagggaaaa ctggaacaac tgaagcagtt
    54781 tttaatccgg agtacacaag tgaccagtgg gtaattggtt atactccgga tgtagtgatt
    54841 agccactggc ttggctttcc gaccactgat gaaaatcact atctagctgg ctctacttca
    54901 aacggtgcag ctcatgtctt tagaaacatt gccaatacca ttttacccta tacgccagga
    54961 agtaccttta cggttgaaaa tgcttataag caaaatggaa ttgcaccagc caatacaaaa
    55021 agacaagtac aaaccaatga taatagccag acagatgata atttgtctga tattcgaggg
    55081 cgtgcgcaaa gtctagtaga tgaggctagc cgggctatct cagatgcgaa gattaaggaa
    55141 aaggctcaaa caatatggga ttcgatagtc aatctatttc gctaagatgc ttgtcaaagc
    55201 ctagctttct tgttataatg gataagatgg aggcgttatg gcactaaaaa aagcaagcct
    55261 agcttgtgcg gtttgtggtt cgagaaacta ttcaatcaag atcagcggaa accccaagcc
    55321 tacacgacta gaagtaaata aattttgtaa gcattgtggc aagtacacta cacatagaga
    55381 aacgagatag gagagagcga tgcgttttat tggagatatt tttagacttc ttaaagacac
    55441 aacgtggcca actcgcaagg aaagctggag agattttcgt tctatcatgg aatacacagc
    55501 tttctttgta gtaattattt acatttttga ccagttgatt gtttcaggtt tgattcgatt
    55561 tattaacatt ttttagaaga ttagtggagt taattacact agaaatcttc tatttatgaa
    55621 aggaaatatc atggatagtt ttgataaagg atggtttgtt ttacaaactt attctggtta
    55681 tgaaaataag gtgaaagaaa atctattaca acgtgcacaa acctacaata tgttggataa
    55741 tattctacgc gttgaaattc caacacaaac agtgcaagtt gaaaaaaatg gaaagagaaa
    55801 agaagtagaa gaaaatcgct ttccaggtta tgttcttgta gaaatggtca tgacagatga
    55861 agcttggttt gttgttcgaa acacaccaaa tgttacagga tttgtcggat cacacgggaa
    55921 cagatcaaaa ccaactccat tattggaaca agaaattcgt gacattttgg tatctatggg
    55981 acaaactgtt caagaatttg atttcgatgt tgagattggt caaactgtac gtattattga
    56041 tggtgctttt gcagactaca ctggtaagat tacagaaatt gataataaca aagtgaaaat
    56101 gattatctct atgtttggta atgacacagt tgcagaagta aacctaaacc aaatcgcaga
    56161 attataaccc tgagagaggc tggagtctct cttttttgtg cagtttagga gctaaaggga
    56221 acagaatgga gaaaatggaa caaatgtgtt ttctaatctg ttagactgta tctagaaagg
    56281 ggaaaattat gattaaagaa ttgtatgaag aagtccaagg gactgtttat aagtgtagaa
    56341 atgaatatta ccttcattta tgggaattgt cggattggga ccaagaaggc atgctctgct
    56401 tacatgaatt gattagtaga gaagaaggac tggtagacga tattccacgt ttaaggaaat
    56461 atttcaaaac caagtttcga aatcgaattt tagactatat ccgtaagcag gaaagtcaga
    56521 agcgtaaata cgataaagaa ccctatgaag aagtgggtga gatcagtcat cgtataagtg
    56581 aggggggtct ctggctagat gattattatc tctttcatga aacactaaga gattatagaa
    56641 acaaacaaag taaagagaaa caagaagaac tagaacgcgt cttaagcaat gaacgatttc
    56701 gagggcgtca aagagtatta agagacttac gcattgtgtt taaggagttt actatccgta
    56761 cccactagta ag
//
LOCUS       DAVKMO010000008        48830 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVKMO010000008 DAVKMO010000000
VERSION     DAVKMO010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.008"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(433..2160)
                     /gene="ezrA"
                     /locus_tag="VW361_000557"
     CDS             complement(433..2160)
                     /gene="ezrA"
                     /locus_tag="VW361_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU9743663.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHASDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2242..4188)
                     /gene="gyrB"
                     /locus_tag="VW361_000558"
     CDS             complement(2242..4188)
                     /gene="gyrB"
                     /locus_tag="VW361_000558"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU9743664.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAE
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLAAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4203..4766)
                     /locus_tag="VW361_000559"
     CDS             complement(4203..4766)
                     /locus_tag="VW361_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9743665.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDISNQGGRHFLVS
                     HRNDQVLEILEKPSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4851..5405)
                     /locus_tag="VW361_000560"
     CDS             complement(4851..5405)
                     /locus_tag="VW361_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU9743666.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5416..6639)
                     /locus_tag="VW361_000561"
     CDS             complement(5416..6639)
                     /locus_tag="VW361_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9743667.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6676..9126)
                     /locus_tag="VW361_000562"
     CDS             complement(6676..9126)
                     /locus_tag="VW361_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU9743668.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SHSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9326..10255)
                     /locus_tag="VW361_000563"
     CDS             complement(9326..10255)
                     /locus_tag="VW361_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9743669.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10395..10682
                     /locus_tag="VW361_000564"
     CDS             10395..10682
                     /locus_tag="VW361_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU9743670.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10716..12050)
                     /gene="ciaH"
                     /locus_tag="VW361_000565"
     CDS             complement(10716..12050)
                     /gene="ciaH"
                     /locus_tag="VW361_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU9743671.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12040..12714)
                     /gene="ciaR"
                     /locus_tag="VW361_000566"
     CDS             complement(12040..12714)
                     /gene="ciaR"
                     /locus_tag="VW361_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU9743672.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12823..15369)
                     /locus_tag="VW361_000567"
     CDS             complement(12823..15369)
                     /locus_tag="VW361_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU9743673.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEARQVASQIFATHKENLAELPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15492..15932)
                     /locus_tag="VW361_000568"
     CDS             complement(15492..15932)
                     /locus_tag="VW361_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU9743674.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDIILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTSESKVVLEEFRKVYPL"
     gene            complement(15907..16776)
                     /locus_tag="VW361_000569"
     CDS             complement(15907..16776)
                     /locus_tag="VW361_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU9743675.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDDDQLKQAITVLRQQGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKIDFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16818..17546)
                     /locus_tag="VW361_000570"
     CDS             complement(16818..17546)
                     /locus_tag="VW361_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9743676.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17554..18033)
                     /locus_tag="VW361_000571"
     CDS             complement(17554..18033)
                     /locus_tag="VW361_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9743677.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(18044..18742)
                     /locus_tag="VW361_000572"
     CDS             complement(18044..18742)
                     /locus_tag="VW361_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU9743678.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18735..19001)
                     /locus_tag="VW361_000573"
     CDS             complement(18735..19001)
                     /locus_tag="VW361_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU9743679.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19067..19993)
                     /locus_tag="VW361_000574"
     CDS             complement(19067..19993)
                     /locus_tag="VW361_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU9743680.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20068..20883)
                     /locus_tag="VW361_000575"
     CDS             complement(20068..20883)
                     /locus_tag="VW361_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743681.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20887..21207)
                     /locus_tag="VW361_000576"
     CDS             complement(20887..21207)
                     /locus_tag="VW361_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9743682.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21583..23580)
                     /gene="metG"
                     /locus_tag="VW361_000577"
     CDS             complement(21583..23580)
                     /gene="metG"
                     /locus_tag="VW361_000577"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU9743683.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEKSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23704..24963)
                     /locus_tag="VW361_000578"
     CDS             complement(23704..24963)
                     /locus_tag="VW361_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9743684.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENTNLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24965..25666)
                     /locus_tag="VW361_000579"
     CDS             complement(24965..25666)
                     /locus_tag="VW361_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743685.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELIERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25650..26849)
                     /locus_tag="VW361_000580"
     CDS             complement(25650..26849)
                     /locus_tag="VW361_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU9743686.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27135..28481
                     /gene="gor"
                     /locus_tag="VW361_000581"
     CDS             27135..28481
                     /gene="gor"
                     /locus_tag="VW361_000581"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU9743687.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFNFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            28678..29214
                     /locus_tag="VW361_000582"
     CDS             28678..29214
                     /locus_tag="VW361_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU9743688.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAILSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGIAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            29265..29351
                     /locus_tag="VW361_000583"
                     /pseudo
     CDS             29265..29351
                     /locus_tag="VW361_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(29420..29635)
                     /locus_tag="VW361_000584"
     CDS             complement(29420..29635)
                     /locus_tag="VW361_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU9743689.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            29733..30053
                     /locus_tag="VW361_000585"
     CDS             29733..30053
                     /locus_tag="VW361_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743690.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(30083..30421)
                     /locus_tag="VW361_000586"
     CDS             complement(30083..30421)
                     /locus_tag="VW361_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743691.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(30433..31152)
                     /gene="trmD"
                     /locus_tag="VW361_000587"
     CDS             complement(30433..31152)
                     /gene="trmD"
                     /locus_tag="VW361_000587"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU9743692.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFNSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(31142..31660)
                     /gene="rimM"
                     /locus_tag="VW361_000588"
     CDS             complement(31142..31660)
                     /gene="rimM"
                     /locus_tag="VW361_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU9743693.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(31691..32479)
                     /locus_tag="VW361_000589"
     CDS             complement(31691..32479)
                     /locus_tag="VW361_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9743694.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(32583..32826)
                     /locus_tag="VW361_000590"
                     /pseudo
     CDS             complement(32583..32826)
                     /locus_tag="VW361_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
     gene            complement(33056..33295)
                     /locus_tag="VW361_000591"
     CDS             complement(33056..33295)
                     /locus_tag="VW361_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU9743695.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(33315..33587)
                     /gene="rpsP"
                     /locus_tag="VW361_000592"
     CDS             complement(33315..33587)
                     /gene="rpsP"
                     /locus_tag="VW361_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU9743696.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33766..33966
                     /locus_tag="VW361_000593"
     CDS             33766..33966
                     /locus_tag="VW361_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743697.1"
                     /translation="MNTILEKFYKEHQVKPFISPERDLDTWLLSPKPVPKRNMNLLAD
                     DSLAGDIILLWRIQFGTFTTET"
     gene            34445..34666
                     /locus_tag="VW361_000594"
     CDS             34445..34666
                     /locus_tag="VW361_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743698.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            34749..35552
                     /locus_tag="VW361_000595"
     CDS             34749..35552
                     /locus_tag="VW361_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU9743699.1"
                     /translation="MKKLATLLLLSTVALAGCSNVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILNTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIGGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(35608..37149)
                     /locus_tag="VW361_000596"
     CDS             complement(35608..37149)
                     /locus_tag="VW361_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9743700.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGIMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHDPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(37151..37633)
                     /locus_tag="VW361_000597"
     CDS             complement(37151..37633)
                     /locus_tag="VW361_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9743701.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLSWLLYKRLHKNKIRN
                     "
     gene            complement(37633..38718)
                     /gene="rlmN"
                     /locus_tag="VW361_000598"
     CDS             complement(37633..38718)
                     /gene="rlmN"
                     /locus_tag="VW361_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU9743702.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIEIVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVNHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLRFNTMKRDRQKVVAAVNP"
     gene            complement(38739..39269)
                     /locus_tag="VW361_000599"
     CDS             complement(38739..39269)
                     /locus_tag="VW361_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU9743703.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            complement(39426..40031)
                     /locus_tag="VW361_000600"
     CDS             complement(39426..40031)
                     /locus_tag="VW361_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU9743704.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(40204..41241)
                     /locus_tag="VW361_000601"
     CDS             complement(40204..41241)
                     /locus_tag="VW361_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU9743705.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(41275..42210)
                     /locus_tag="VW361_000602"
     CDS             complement(41275..42210)
                     /locus_tag="VW361_000602"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU9743706.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(42763..43953)
                     /locus_tag="VW361_000603"
     CDS             complement(42763..43953)
                     /locus_tag="VW361_000603"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU9743707.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLIRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(44168..45511)
                     /locus_tag="VW361_000604"
     CDS             complement(44168..45511)
                     /locus_tag="VW361_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9743708.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATVPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(45651..46466)
                     /locus_tag="VW361_000605"
     CDS             complement(45651..46466)
                     /locus_tag="VW361_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9743709.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLSEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            complement(46518..48698)
                     /locus_tag="VW361_000606"
     CDS             complement(46518..48698)
                     /locus_tag="VW361_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9743710.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFAPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVAAYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEV
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
BASE COUNT        14518 a        10662 c         8780 g        14870 t
ORIGIN      
        1 aagaggtttt agaggcctat ttaccgtggg actaaagttg tacaagaaaa gtgcaaataa
       61 gaaatctcca gattaggaac tatccgtgag ttctctagtc tggagatttt tcaatagact
      121 tcgttattgg acggttacca agttactcaa agtacagatt tgaagctgca gataagattg
      181 acgaaatcac tttaatacta aatgaaaatc aaaaagcaaa ctaagaagct agcctcaggc
      241 tgtacttgag tacggtaagg cgacgctgac gtgatttgaa gagattttcg aagagtataa
      301 aacactgttt tgaggtggtg gataaatcgg ctgggtaaaa actcaatctc aggagaaaat
      361 gaagtaaatc tccccacaac tatagaaaaa gatttgattc tgctcctcac acaataaaat
      421 ctttttcttt tattaaaaac gaatcgtttc acgtgttttc tcatatgagg taacaaagcg
      481 attggttaca ccaggctctg ccacttccaa tgcttgagaa atcttgtcaa atgaagcgtg
      541 ataatcaaat tctttttcaa aaatatctaa agcttcgtta aatgcttctt gaatgcgttc
      601 atcaaatgag cgatagcggt tagaatattg caagagttgc tctgtcaaag ttgcatattg
      661 tacaatatta taagtttccg tttctaaagc ttccatatca ttcgttgcaa tttcaagaac
      721 tcgggtaaca gattcaatgt taatcatttt ttgttctaac tcaaccatta aatcctcggt
      781 attattgctt gccgtaaaga ataacttcaa gaaagtttgt ggaatacctg gcagattgcg
      841 tttttccatg tatcgcttga tagtatggag acgattgaca taaacattgg ccttttgacg
      901 tgcattaata tcatctttct caatttgtgt caggcgctca ctaactgaaa tttgctcatc
      961 ttcaatatct tttagttgag tttgtaaatc ctcaagattt tcttcaagaa ctgaataagc
     1021 ttgggttggt tcttcttgat ttgaagttac ctcaacaata gctgcctcaa aactctctaa
     1081 ttctgtctga atacgacgaa catggcttgc agctgtctca ggaagtaaat aggtcttgtt
     1141 caaacgtgca atatcttctc ccaataaagt attattctct ttcatatgtt gaaggtaagt
     1201 tggaagagtt gcaagtagat tttccactac tttctgagca gcaatttctc gagtaaaaat
     1261 atcatacaag gcattgattt cctcttgtgc ctgtccattc tcatattcgg cattatccaa
     1321 ttccaactga cgaatattct cttggttttt cttgaatgct tcataaagca agtggaaacg
     1381 cgcttcaata tccgtttcaa caaaatgata attagcatca attagtttac gataaccggc
     1441 ttccaaatcc tgtaattgat ctggcaattc tgtagaaagc gtcgtaacca aggctggaac
     1501 acgatccaca atatgactta aggccaaaat gtgattttct gtattatcca aaatcactgc
     1561 ggcttccaca gggtcacccg atgaattcaa ggttacaaat tgtgaaaatt cagattggat
     1621 attttctaat tgtttttcaa tttcatccaa ggcttgacca tactgttctg aattttcagc
     1681 aactctatgc tgaagttcct caaataaatc cgaagcatga agaacacgac cactattttt
     1741 agattcttgc ttctctaagt ctgccaaagc attgcgaatt gccgcaatat cttcttcaat
     1801 caaagtaatt tgactctcaa tttggtcaat ttgatgactg gccttgagaa aacgaaatga
     1861 atggttatag ccttctgctt caaagagatt attttcaata tcggcaaaag agttgagaga
     1921 taaatcgacc catttttgat tccattcacg gaaagccact tgactttgtc caatcaagtg
     1981 catatttttt acagcttcta cttcatcatt tactggaaga ttgtatagtt cttcttttct
     2041 ttcttctagc gcctctaatc tcccctcgtt tcgcttacgt agaaagattg ccactacata
     2101 agccagaact aaaatgactg caattgcaac cattaaataa attagttgtc cattagacat
     2161 atcaaactcc ttttttactt gaaacaatcg taacaattat atcatatttt ttagaccaag
     2221 ggaactactt ctccctattt tttagacatc aagtgtacta tagacagcat tttcttcgat
     2281 aaactcacga cgaggctcta ctcgatcccc catcaacata tcaaagattt tatctgcttc
     2341 tgcagcatca tctacagaaa ctctagccat caagcgatgt tcgggatcca tggttgtttc
     2401 ccacagctga tgatcgtcca tttcacctag ccccttataa cgctgaatag tcggtttggt
     2461 acgaccttca ctataacggg ctaaagcttc ttggagtttg atttcttgat ctgcacccgg
     2521 ttggatatat tctttaatct cgcttccaac cttgacacca tagattggtg gttgggcaat
     2581 ataaacataa ccagcttcta ggattggttt catataacga taaatcaagg ttaaaagaag
     2641 ggtacgaatg tgggctccat cgacatcggc atcggtcatc aaaacgagtt tttggtaacg
     2701 ggctttcgaa acatcaaatt ctgcgccaaa tcctgttccc atggctgtga aaagactacg
     2761 aatttcttcg ttagctagaa tcttatccat acttgctttt tcaacgttca aaatcttacc
     2821 gcgaattgga aggatagcct gaaactcacg gttacgacca gatttggctg atccaccagc
     2881 tgagtctcct tcgacgatga agagttctgt ttcagcaggg ttattagaag aacagtctgc
     2941 tagtttccct ggaaggttgg aaatttccaa accagatttt ttacgtgtga cttcacgcgc
     3001 acgcttggca gccacacgag ccttggcagc caaaattcct ttttctacga tacgtttggc
     3061 aatctgtgga ttttccatga ggaaatcgga gaaggcttca ctgaagaggc gattggtaat
     3121 cttgaccact tcgctatttc ccaatttggt cttggtttgt ccttcaaact gtggatttgg
     3181 gtgtttaact gagataactg cagctaagcc ttcgcgaaca tcttcccctg ttaggttgtc
     3241 ttcattgtct ttcagtaact tatttttacg agcataatcg ttgataacac gtgtcaaggc
     3301 tgtacggaaa ccttgttcat gcgttccacc ttcatgtgta tgaatattat tggcgaaact
     3361 catgacattt tcatggtaac ccgttgtata ctgcatggct acctcaactg tgatatcatc
     3421 catctcaccg tctgtataga ttggtgtatc aaagattaca tccttgttct cgttgatata
     3481 ttcaacgtaa ctagcaatcc caccttcata atgataatgc ttggtttgtt ccaaaccttg
     3541 gcgcttatct gtaattgaaa tttgaagacc gcgatttaga aaggccaact cttgaatccg
     3601 tttatttaat ttatcaaaat caaagattgt tgtttcagtg aagatttttg ggtccggtgt
     3661 gaagtgaaca gttgttcctg ttttatccgt atctccaact atttcaagtt ctgcgacaac
     3721 atgaccacga cggtattctt ggtaatgaat cttaccattt ttgtgaacat gaacgtctaa
     3781 ttgagtggaa agggcattaa caactgacga ccccaccccg tgaagaccac ctgaaacctt
     3841 gtatccacca ccaccgaact ttcctccagc gtgaaggact gtaaagacgg tctcaacagc
     3901 aggacggcct gttttttcct gaatatcgac tgggatacca cgcccatcat ccacaacagt
     3961 aatcgaatca tctggctcaa taaaaacttg aatatggctg gcaaatcctg ccaaggcctc
     4021 gtcaattgag ttatcaacaa tttcccagac tagatggtga agaccttctt ttgaggttga
     4081 tccaatgtac atccctggac gcatacgaac agcctctaag ccctctaaaa cttgaatttg
     4141 actggcatca taatcctgtg cctgcagatt tttgatttct tctgtcatct tattcctttt
     4201 tcttatatgt ctaatacttg tcttaaattc acgatactgg taaacaagtg ggtatcaagt
     4261 cctgcagctt gacctgcttc gatatcaatc ggccgatcac caatgacaag accagagcta
     4321 atctgatact tttctcttaa ataaagcatg gattcgggat ttggctttct cttaaagcct
     4381 gagctagaag tcaccacttc tgtaaaataa gctgctatag agggtttttc taaaatttcc
     4441 aaaacctgat cgtttcgatg agagaccaaa aaatgacggc caccttgatt tgaaatgtct
     4501 tccaataggt cagaaactcc ttcaaataaa atcgggtgtt caagctctct ggcttcattt
     4561 tccttgtact tttctaaaaa attctctaaa ttgggagcga atgtctcaat cgcaaaagga
     4621 gtagaaacct ttaaagcttg atagacactg tcatggtctt gtgtgatacc atacagtgcc
     4681 aatgtttcaa caaatgcagc tgttgaagtt tcataattat ccagtaaagt tccacctaaa
     4741 tcccagatgt aatcgtgata tttcataccc ttcattatag cattttttta tgaaaaaagc
     4801 gatgatttcc ctgagttttc cacataaaaa acgagagaat aactcccgtt ttactgattt
     4861 ttaccaaaga catctcgata gagcattcct gttcgtaaac tctctgcgtc ccctcctagt
     4921 tgctccacca actcgtaggc aaaggcaagg gctgttgaag gaccccgact ggttgtcaac
     4981 tgaccatcta ccactactgt ttccttgacg tagtgaccat caaggatttg ctcttgaacg
     5041 ccgtcataac aagtgtatcg cttatttttc aatatctctg cttgattgag ggcaattggt
     5101 gccgcacaaa tggctgctag tttcttccct tcttgctcga agctttgcaa ttcttgaatc
     5161 aaggtctgat tatcacgtaa atgtgcagaa ccaggcatac ctccaggaag aacaatcata
     5221 tcatagtctg ataaatttcc atcaaagaca tgatctgctc ttacttggat tgcatgcgaa
     5281 cccgttactt gctcttcaaa accaaccata tcacatgtga tattggctcg acgcaagaca
     5341 tctacaactg tcaaggcttc aatttcttca aagccctgag ctaacataac tgctactttt
     5401 accatgattt tctccttatt taatttgttt taatacaacc tttttccgtt tgaatgggac
     5461 ttttccgctc ttttcttcag ctagattagt ctggtaactc atcgataaaa gcaaaccaac
     5521 accaatcaga ttactgataa tagctgatcc cccttgcgaa atgaaaggca agggaatccc
     5581 cgtcaaagga agtagtccag tcacagcacc gatattctca aagatgtgga agagcaacat
     5641 cataatcaaa cctgtggaaa tataagtgta gaactggtta tttgatttaa gagtaatctt
     5701 caacatacgg taaatcaaca tgagatagag ggcaataacc aggacagagc caataaagcc
     5761 aaaatcttct gcaataaccg taaaaatcat atctgactct cgaactggga taagcagatt
     5821 cgaagcatta aatccctgac caaataagcc accactccca atggcaatct gcccttgagc
     5881 ctgctggtaa gtcgttgttt gggcaaactc aaagggattg agccaagcca aaatccgatt
     5941 gatttggtag gtcggcattc caatctggtg aagaaaagct cgtccgtcct tgctaataaa
     6001 gatagctaag aaaccagcaa ctcctgttac agcagtcaca aatactggga taataatttt
     6061 ccaagaaacc cctgataata aaacgattcc tgagaaaatg gctacaaaaa ccaaagccgt
     6121 ccccaagtca ctttgaagtg ctaaaagaac taggactgga atggtaaaga gaatcatcca
     6181 gaaaattaac aaaaagtcca gcggaaccgt gcgtctccat tccttatgtt tctttgtaaa
     6241 ttggacaatg acacgagcca acatgaggat ataggatatc ttcataaatt ctgacggttg
     6301 aaatagggta attccattta ttgataccca gtttttggca cccgttgatg caactaagct
     6361 tggattataa aatacaatcg gcaagatcat aagtcccaag cctaaaatat atagaaaggg
     6421 ggtcaccttc caaagaaatt ctgtattaaa gagcatgacc acaaaaccaa tcacaagccc
     6481 caaggcaatc caggcgacct gctgccctaa aatgggcaga atattattgg ggtaatcatg
     6541 actaacggct atatagatag ccaccacacc gatgaccagt agaaaaaata ctggcaagag
     6601 caaactgtaa tcgactcttg agtcgagaga acgtttcata tatactaacc ttatactttc
     6661 atacaatact atttatcaaa gttcattaaa aaatctatca atagcctcgt caacttcgga
     6721 tcgagagatg gttttaacag tcgcttcttc tgctagagat gctactattt gtttgccgta
     6781 tcgttttccg acgattctcc tatccaaaat aagagttaag gaacgttggt attcacgtct
     6841 catacttctt cccaaagcct gttttaaacg aataatggcc attggcaatt gataatcata
     6901 aaaggcattt ttcccttctt gattcagttc ttgattaatc tttttcgtca agggttcttg
     6961 aggattttgg aaaggaagcc tcggtacaac ttgaatcaca aaaggatggc ttgaaaaatc
     7021 aactccctcc cagaaacttg ctgcaccaag caagatttgt tgttcacctt tttcaaagcg
     7081 tttctttagc tgatgaacat ccccattttt atactgggcc aagtggctaa ctgtaagtaa
     7141 atccgatact gctagaagca tgtctttagc ggtaaagaga accaaaatcg gttgctggaa
     7201 agcttgaatt tccactagta aagcagctac ctctctggca tagacttcta aggaggtttc
     7261 tgttaccaga gggaaatctt tgaccatgac cacttcttgt tcctgttttc cccgagattc
     7321 aatcttgaca aatttagctt caggatagcc taaaaggtct gccaaagaaa ccctctgact
     7381 aatctcaaga gtagccgata ctcccaggac ttggcaactc tcaggaagta aagaggacag
     7441 aagagtacgg cctgattttg tagaagaaat ctgaattttc ttttgactcg tttcagttac
     7501 ttcaagccag taatcacctt cagctgtaaa atagcgaacc agctcatcaa agccttctac
     7561 ttctaattct gaaaaatact gatggagatt atccagagaa tctaagatat ttttcctaga
     7621 tttgccagac tgaaattgtt ctatcaagta gagacactca aagcgaatac tttctagtat
     7681 ccgttgttga accctgtttt cttctcctac taaagcctta tcaattaaat cgataataga
     7741 ttgtatatcg taggtctctt gaagcagatt ttctagagct aacaaaatct tttggacttc
     7801 atcaataatc agtaaacggt cactgacaaa ttcaggatta tcttcaagtc tggtcacgag
     7861 ataggcatga ttagtcacta aaagcttgca agtctctgcc ctttcttgac tacgtttcca
     7921 aaaatcttcc gtcacaaata agctatggga tgataaattc ccatcatgac gaaggtctgc
     7981 tagaaaatgt tggtaacggt agagttgccc gatttcatcc aaatctcctg tctctgtctc
     8041 agtaagccag accaagactt gcattttaaa gcgtctaaat aagcgatttt catcattttc
     8101 ctgcaaggaa tgataaaagg catccaactt cagataattt tgtggtccct ttaagctatg
     8161 aatatctgta tggaacactt ccttgagacg tttaccttct tcttccatga tttgattttg
     8221 aagaatcttt gtcggaacac taagaacaat ttgtcgctct ttggattgag ataaagcggg
     8281 taagagatag ccataggttt tcccaatccc tgtcggcgct tgaatcagag agacaggttc
     8341 atctttcaat agcaagccaa cctctttagc aaaactttct tgttcctccc tcacttcaag
     8401 gttcaacaga gaaatatttt tagaaaagtc ttgagatagt tttcgtagct ccagagaagc
     8461 tgccgttttc ttaaaataca gaccttgaac ttggaccaag tctggagaac tcaggataga
     8521 ttggttgcga taagtttcct caataaccag gtaggactca tataggagag cgtcagccat
     8581 ttccagcaag cgttccaaga gacctttagg aagctgggtc atcttttccc gtaaaaaaag
     8641 aagtaattct gctgtagctt gggcatctga aagggctgtg tgtgcgtgtt taagaggaat
     8701 tcctaattct cgacacaaaa tcggcaagct atatttttcc agttcaggga aaaagacctg
     8761 ggccaattcg accgtatcaa cacgagggtt tcttagctca tagccttcaa aaaataaatt
     8821 ttccgccaag agattagcat caaactgaac attatgggct acaaaaatcc catcctccac
     8881 caagtcaaag atttttctgg caacttgcga aaaatcaggt gcttgcgcca gacgttggtc
     8941 tgtcaatcct gtcagttctt tgatatgagc atccaagggt tcatgtggat tgacatccgt
     9001 cgtatagtga tcgacgattt ctccatcctc aatcacgaca attcccactt ggataatttt
     9061 agccttacta cctgtgctag ttgcctctaa atccaccaca acatagcgat taccaatcgt
     9121 tttcattata aaaaattata ccaaaaaaag ggccatttgg cacctgcaaa cataggataa
     9181 ttttcaaact caagaacact acttttctta gaaatcccat cgaatagagc attctagcct
     9241 gctgattttt ttaaaatagt gaagaaatac gaaaaattga gagaagaaat gttttcatct
     9301 tccttctctc aacgaatcat gtattttatt taaccatgtc aggatcgtag tcataaaatc
     9361 ctgtatcaag gaaacggttt ttagggtgaa gtttacgaac ttcttcatcc agcaagaagg
     9421 cttggtcatg gctaaagttg ccctcttgaa tcaagctacg cgcttggata aagagttttg
     9481 caatctcaac aaagttctga ccaggagtgt agagcccttc tagtttccag cgagtaaagc
     9541 catgctccac caattctgtt aatttgatca tcaaatcaag gtcattgttg gcaaagatat
     9601 gggtcccatg attatcttca aaaatggaat agtggctctc tggatcactt ggctcagcca
     9661 agaagaggtc acgtttatgc gtcttttcat catcgatatg tgtaaagtta tagtagtttt
     9721 gcaagagtgg acgtttagaa tgatggatga cgctagcacc gtaaaccaaa acttcagcag
     9781 gaatttccaa aatctctggc attttgaaaa gttcagctga tggaatttca cgcgccaaaa
     9841 cagcctcaga tgcgccagcc ttttgtcccc agaagttaat ctgacgactg ctagttacca
     9901 tggttgaagc atcgtagatg gtcttaaatg aataaccatc gcggttaact acgtaaaaga
     9961 cgcctgcatc cccaatcgta atatagtctg tcttgatttc ttccaagaag tctaagaaag
    10021 gcttgatacg gtccatcata tcttggtgca tgagagcatt gaccgcaacg agcaattcct
    10081 taccagcatc atgaaccaac ttagcgattt cacgtaattg gtcataacta aaggtcgttg
    10141 gcagacgaag gccaaaatct ttctcaccga catagatacg gtctacgcca gcttcgagta
    10201 gttgttcaac ttgttcaata ctttcagcag ttgctgtaat gacaatcttt tccataagaa
    10261 aaattatacc acatttctcc aaaatcatcc atgctttgaa aatgaaaagg gactttattc
    10321 tttttgtaac ctttctgtaa taattttctg ccgaaaaaat gataaaatag gtatgtactg
    10381 ttaaggagag aatcatgccc gtaagaaaat tacaatccta tgaggtagac tatcaagaag
    10441 aattaaacca gcagcttcct cattaccaag cttatacacc tgaagcgcaa tctgatgcca
    10501 atctcaagga aatcctattt tttattaata tcgctgtttt ttgtatctgt attgctatct
    10561 ttagttttat ctttttagca ttaaaattat caactgctct tgcctttgcc gcagcaatcg
    10621 gattcagctt acttgtttta aaagttcaac ggtctattat caaacgaaaa cgtagaagat
    10681 aaatccaaaa tatcgcccca attggagcga tatttttatt ttttcttttt agatggtgtc
    10741 tgaatggcaa tcttcacttc aaagattgtt cccttgggtt tattatcttt gacagtaaca
    10801 gttcctttta gagcatctac aatttgcttg gctagggata atcctaaacc aaaaccacct
    10861 ttttgccggg ttctagcctt gtctactcga taaaaacggt caaaaatttt ctttttatct
    10921 tctgtcgaaa taccgattcc attatcagaa acaagtaaat aaagattgcg atcggtcgcc
    10981 gagataagaa aatcaatttc accatcctcc tcagtatact tgacggcatt atcgaaaaga
    11041 atggtcatca gttgtttcag aagaagctga tctgtgacaa ttgttcgatg gatacgattt
    11101 tcaaaacgga agacacgatt attttccgaa gcaatcatct catagtttgt gaaagttgta
    11161 ttaaaaaagc tagttggaac ttctgcaagc tccggcttaa tcccatcatc tctccgagct
    11221 aagttcagca agcttgtcgt taaaaaacgc atatttcgga cttcttccaa actcgatgca
    11281 atgctttcgc tcacatccat aatggtagct tctggcttac gaaaaagggt ctctaagcga
    11341 ttttgcaaaa ctgcgagtgg agttcgtaac tcatgactgg cattttccac aaaagactgt
    11401 tgcttctgca tactctcaag caggggccta acactgaccc tagctagata gagactggca
    11461 agtaaagaca aaatccagaa actagccatc acgaccacaa tcaattgctc atgcttttga
    11521 ctagcctgct ccaactgact ggtattaatc aagacagcag catacttgat attggttgaa
    11581 accgaactaa tattggtctc catcaaaatc acacgataga tttcttcctg cccatagcta
    11641 ttaaaaacct gaatctggta gatatgtcct agttctttct tttctaactt aatcttatcc
    11701 aagcccaaaa atcgatttcc agaaagaagt tgagtaaagt ctttatcaaa gagaatgact
    11761 tccgtattgg aactgacatt aggttttatt tctactttac tagcgtccgc cctagcattt
    11821 tctaaatctt taatctcttc tgttgcccta tttatagcca gctgaataac tgcttgagga
    11881 ttttcactca gtccatgaag cttatcgtcc accgaagtat aaagactcga atgcatgact
    11941 tgtaaaataa tcagagtcat tgtagaaaaa atcagggtga agacaccgaa gttgcggata
    12001 aaataactaa agtcatccgc ataccatgtt tttttaagtt tactgaacat cttttaaaag
    12061 atacccaaca ctacgcaagg tttgcaaatt ctctgcaaaa gtggttccct ttaatttctt
    12121 acggactttt gaaacataga cttcgacaac cgaaatcgtt gtatcactat caaatcccca
    12181 tagacggtca aaaatctgcg tcttaggcaa aatcacattt tgattttgaa ggaaataaac
    12241 tagtaaatcg aactctttcc ccagcaattc gacaggagta tcttcaactt taacggtatt
    12301 ggttgataaa ttaaccacga tattcccata agtcaaggtg ttttcattaa acttccctga
    12361 acgtttgaga agggcctgaa ttcgcatttt aagttcttct aggtagaaag gtttggtcag
    12421 ataatcatcc gctcccagtt caaatccatg tcccttgtca tccaaacttt ccttggcagt
    12481 cataatcaga actggtgtcg taattccctt ttcacgcaat tcttttaaga cttggaaacc
    12541 atttttttct ggcaacatca aatccagcaa aatcaagtca tagacaccac tctcagcttc
    12601 gtagagacct tcttctccat caaatacctg cataacatcc gcaaaatcgt ctaaaaagtc
    12661 aaatactgaa tttgacagac ctaggtcatc ctcaaccaat aagattttta tcatgagaaa
    12721 ctcctcctta ttaaaactat tataccaaat ttgccttaaa aaaaactcaa ctctctgcat
    12781 tttacatgag atagctgagt tttcttttta ttttaggctt atttatgcat ttccgtattg
    12841 aagaacaact gcttcgactg cagctttttc acggctaatc aagtcaacac gtgctgcaat
    12901 ttccttgatt cccataccga tgttacggct aagagcaagg tcagaaagtt gcggctcaaa
    12961 gaactccttg tattccgcca agcgttgctg agtcttaaat acatgagcag gaaggataac
    13021 aaagctatca aagctcatat ctcctccaag ggctgcctta atccaagccc agttttcacg
    13081 cgcccaagac caagctgttt tctgagttgc ttgatgagct aggaattggt aataccaagc
    13141 agacaagtcc tgtggtttga ccacaaattt gtccttccaa gaagtaatca agttttggat
    13201 attatccgca tctgtactgt atgcaagagc tgctgccaac tggcgtttaa agacagcatc
    13261 tgttgcgtga gtataagtat caagataaag tgctaacaag tctttagtct catgatgttt
    13321 catctcatta atcagaactt gtgaacgaat agctgctggg agttctgcaa gattctcctt
    13381 gtgtgttgcg aagatttggc tagcgacttg acgagcttct gcatcatttg agcgaatcat
    13441 catcgaaaca gccagctgac gaaccaattc atcctcatct gattctccgt ctttagcttc
    13501 aaaaccaaga cggtcatagt tatgacgagc caatttagca accagtcctt tgaaggctgt
    13561 ttcagcatcc gttccttcat caataaagcg ctcaagggct gaaatcactt gagaaacagc
    13621 tgaaaccacc agataagact cttccttagc aagtttatca agaactggaa gcaagtctgc
    13681 ataagaaatg tgccctgcct cagccaacaa acgacgttct tgaacaattt gcagtttgct
    13741 tgtgttatca agtgtctcta gctcagcaag aacagcttct aacaagtctc cttgatagtc
    13801 ggtaatatag tgggcagtat tttcagtgtt gagacgaaga gctccttcat tttcagcaag
    13861 aagagctgcg tagccaggga tttcgatact ttcagtttcg agtgtatcag gcaagccttt
    13921 ccagttgcta ttgaggggca ccacccagag acggttcttg tcttcgttct caccgatgaa
    13981 gaattgtttt tgtgaaatct tcaagacatc attttcaact ttgacagtaa gaactgggta
    14041 accaggctgt tccaaccaag aatccatgaa ggctgcgaca tcacgtcctg acgcttgacc
    14101 aagggcatcc caaaggtcac taccaatggt gttgctgtat tggtgttttt caaagtaggc
    14161 atgcaaacct ttagcaaaat cagcatctcc tagccaacgg cgaagcatgt gcatgagacg
    14221 gcttcctttg gcatagacga tagcgccgtc aaagagtgta ttgatttcat ctggatgttt
    14281 aacttcgacg tggacagact gaacgccatc agtagcgtca cgttcaagag caagaggtac
    14341 tccacctgtt tggaaatctt caaagatatt ccagcttggt tcgatggtat ccacacagac
    14401 gtattccatc atattagcga aactttcatt gagccaaagg tcatcccacc atttcatagt
    14461 cacgaggttc ccaaaccatt ggtgagccaa ttcatgggcc acaacaaggg caacttgttg
    14521 acggctagca aatgtagagt tctcatcgac aaccaagtaa acttcacggt aggtcacaag
    14581 accccagttt tccatagcac cagctgagaa gtcaggaagg gcgatgtgga gagattgagg
    14641 aattggatac ttaactccat agtaatcttc gtaaaactcg atagagcgaa cagcgatatc
    14701 cagtgagaaa tcaagatttg aaagtggatg tgctttggtt gagtagacac ctaccagggt
    14761 accattttta gttttagcgg tcaccccttg caaatcacca gcaacaaagg ccaacaagta
    14821 agaagacatg cgaggtgttg tctcaaactt ccagatacct gtttccttac ggttttcaac
    14881 atcgatttct ggcatgtttg acaaggccaa ttcaccttct gcttggtcaa agcgaagaga
    14941 gaggtcaaaa gttgctttgg cttcaggctc atccacacat gggaaagctt cgcgcgcaaa
    15001 atggctctcg aactgagtag acaagacctc cttcttgact ccatcaactg tataataaga
    15061 agggtaaatc cctgtcatgt tgtctgtaat tttaccagaa aaggcaagaa ccaattcaac
    15121 ttgaccagcc tcagccaatt cgatatgaag ggcttcattg tcatggtcaa ctgtaaatgg
    15181 acgagcttga cctgcaactt ctacagaggt gatttccaag tctttttggt ggagggagat
    15241 gcggtcactc tgtgcttgac cagtgatggt cactttccca gaaaaagtct tggtctcacg
    15301 actcaaatct aaaaataaat cataatgttc aggaacaaat tgcttaataa aatgttcaac
    15361 tgcttgcata gttttctcct attctaagtt taagagctgc tgctcttctt caaacaaact
    15421 tattatatca tattttgctt gaaaaaaaag gattggacag cgatttccaa aactttcttc
    15481 cttctaatag tctacagtgg gtagaccttg cgaaattctt ctaaaacaac cttgctttca
    15541 gatgtaaaag tcagccctac ttcacccaaa cagtctgtga aaaagtcctc atgaacctgg
    15601 cgccaatagg caagtgattt gtctccctca ccttccttaa aggcatgttg cgcagaaact
    15661 tgattgaaga gttcaacaga aacctttgta atttcgacaa tgcagacaga ctgattttga
    15721 ctatctaaaa tgatatcgaa ggtccctact tggggaagtg gttcgtcttc tagtacatag
    15781 aggtcatagg ctgatgctgt tgctgtcttt tctcctttaa acaccaaatc cgctaaaaga
    15841 tctggttcaa ctccaaaagc ccaagcatcg atttcatctc cgatcaaagg attgatttgc
    15901 ttgtatttat tccacatttc ttgcggtatc atgggtactc ctttgtaatt ttttactttc
    15961 ttcttttatg tgtttaagat gatctggatg gtcaatctct aaatcaaaaa tctctggaat
    16021 agaactgtag tggataatgc acttgatacc caactgattc attttttgta tgaaagaagt
    16081 attcagatag cctgctacag caaaatcaat cttgttcttt cttgctttat cctgcatatc
    16141 tcttagcata tctaacatta ttggactttc catatcatgc cattgactgt ttctcatagt
    16201 cgcaaaaaca aaggaagtca aatcattcat tccaactaca atctttgaaa tgcccgtttc
    16261 cagtatacta gataagtcaa aatacgctga cggtaattca atcatcgttc cgactttccc
    16321 agtaaaaccc tgctgacgca atactgtaat agcttgtttt aattggtcgt catcattgac
    16381 aaaaggaaag ataacagata gattggggtt ggtttgataa acttctgtaa cgacatgtgc
    16441 ttcagcctga aattcatcca aacacgccag taaacgcctg gttcctctat agccaaacaa
    16501 gggatgccct tcgtcaaaaa actctctagt ccccactaaa caattggctt ctgtattcgt
    16561 taattcagaa aaacgatacc aaacttcttc atctgagtac agggagcaga tagtctctag
    16621 ataatctttt acaaattgct gacaacttgc taatatgatg ttttgattaa gctctctcaa
    16681 caaatattcc ccacgaatca tgccgacgtg gtgaaatagt tgaggataaa ttttttcaag
    16741 aattttttcg ccactaaggg caagttgatt tctcatagcc attcacctcg tcttaaaaga
    16801 tacaatatca tatataatta tatcaaaatt tcctctagtt caaaagcttc ataaggttca
    16861 gataactcat atcctaaaaa ttctgctact tttttggaag cctcattatg agcatcccaa
    16921 agtggaaaca tatctctatt taaactctct agaatcattg cagcaccaag ctttttagca
    16981 aatccatttc cttgttcgtt tggtctagtt gcaacttcca cttcaactgc tttacggtaa
    17041 actaaccctg aggaaatccc agcaatcagt tcattatttt taagaatcac aaagccaaat
    17101 ccacctttta aaacaaaatc ctgataggac tcaaaatccc cctgtaaatc ctgtgaccat
    17161 tcttccgtag aaaagcagtt ataaatatga ttatcaatag gcacaatatt gtaaccttcc
    17221 tctaaatgag taactagatt atttaaaaat tcaacttgaa aatttgcctt atctttaaaa
    17281 gaatagcgag taaaagaatt tagccccact tttcgatgca gaaaatcttg ccaattagta
    17341 ttttctgaaa taataatctt ataatctaaa ccatattttc taacaaaatc ttcccaaaat
    17401 ctggaatcca actcccctgc taggtataga aaattcccaa catcataaaa gcttgttgtc
    17461 ctatcattgt ttcggtagac agttccaatt tgagatttaa gaccatagag aaccatattt
    17521 ttcttccatg ttttaaatag ttccattatc cctctacttc accttccaat tcatgtaaga
    17581 agtcttgtcc agttctggca atcctaataa ttcagactta accttcaaga ctaatggcga
    17641 tgcattttct tctgtaatct cttgaatatc catccaaata tatccaagtg aatcattcgc
    17701 accatcagac acagcttccg aaatcgtaac ttgaggtgca ctctcattca tttcaacatc
    17761 atacaaggct atgacatggt gaaccataaa attttttaac tcttccctga cgaaaacatc
    17821 gtagattcga ggattagagt agcttctaac agtaaatccc gtctcttcca taacttctct
    17881 agtcagcgtt tccgtcagtc cttcaccaag ttgctgactg cctccaggta gatcataccg
    17941 atgttgataa gggcctctcg ttttttcaat gcaaagtaac tttccatttt caaagcaaac
    18001 acagtagacc ccaaagtgat ttttgatttc catccaactc ctcctacttc aaagaccagc
    18061 caccatctat tgtcagaatt tgtccctgca tggcagatgc ctttccactg gccaaaaaga
    18121 gactgacttc tgccacttcc tctggttcaa tccagcgctt gattggtgtt tcactagcca
    18181 cccagtcagc taagccacct gtctcaaaat ccgcagcggt catagctgtc ttgactgctc
    18241 ctggagcgat accaaagacc tgaatcccag cttcagcata gtctagagcc aactgcttgg
    18301 tgaagccagc caaggcatgc ttggatgaag tataggcgtg accacctcca cctgctaggc
    18361 tagaagcaat ggaacacata ttgatgatga ttcccttttt attttccagc atttgtgtca
    18421 aataataccg agtcaactct actggaataa tgtagttgat ttcaaaaatc tcttgaatgt
    18481 cctgcgccgt ttgttccaac agtggtttgt aatcatccaa aactccggca gtattacaca
    18541 aaacatccac ctgagggcac cagtcaaaaa taggttccaa gtccaaggtc aaatctctct
    18601 gtaaaaagtg aaaatcaccc tctaagagtg gcttttcacc ttggtcaact ccataaactt
    18661 gatagccctt ctctaaaaag aggcgagctt gagccaatcc gatccctgaa ctcactcctg
    18721 taatgagtac acgtttagtc atgcacttct acccaatccg ttgccaaaac atcacaaact
    18781 gtcgggctcc acatggaaaa accttctcct tcgccagaaa cgttgattag gaaataaggt
    18841 gtcatttcaa gtgcaagccc attttgctcg atggtatcaa agagttggac atagttttcc
    18901 gcacctcccc aaccagttcg tacatatttt ctcttagcct ttaacccagg caggatctct
    18961 tcaaatgtca tgtttttctc ctttaattct acattcttca tttaattata gcaaaaaacc
    19021 actttatacg gctttttgac tgtgagttat tcaaacctgc tactacttac ggcaaattat
    19081 tccctgcagc aagataaatt tcataccatt cttttcttgt taagctaaag tttgccgctc
    19141 ggctaacttc tctcaagtgc ttaggatttg ttgtacctac gactgcctgc atttttgctg
    19201 gataacgcaa tatccaagaa atggcaatag ttgaagaggt tactccatat ttaatagcta
    19261 aacgatcaag tacttgattt aaagcttgaa atttctcatt tccaacaaag ttccctttaa
    19321 aatacccgaa ttgcaagaca gaccatgctt gaatgaccac atcgtgtaat ttgcaatatt
    19381 caaaaatgct gccatctcgc atagctgctt gactatcttc catattaaca tgaaaagctg
    19441 attcaaatcc tggagtaaaa gccgcactca attgtagctg attaacagct aacggctgct
    19501 tgacatcttt tttaagcaac tccatcatca taggattttg attagaaact ccaaaatctc
    19561 gaactttacc ttgtttataa aggagatcaa aggcttctgc tacttggtca gattccatca
    19621 aagcatctgg tcgatgaagg agcaagctat ctagatgatc aatcttcaat ctttgcaaaa
    19681 taccgtctac tgattttata atatagtcct tagaaaaatc aaaataggta aattcttcaa
    19741 tgcgaatgcc acatttggac tgaatccaca tcttttctct taaatctgga cgatttttta
    19801 ggacaagacc taacagttct tcacaacgac cacgaccata aatatcagcc aagtcgaagg
    19861 cattgattcc aacagaaagt gctgtttcta caagctcttc aacttctttt acagacttat
    19921 cttttattct catcattccg agaacaattt ctgataattc tttgtcatct tgaccaagag
    19981 ttatgtatct catcaaattt ttctccttta atttctaaca ttcttccctt cattataaca
    20041 aaaaaccgct ttgcaacggc tttttgacta tacttcactc cattttatct tcttaaaccc
    20101 acggaacaag acaaagattc caataaagag gacagctaaa ggaataactt ttgtaaggaa
    20161 aacatttgaa attcccatcc actcataata acggagcaga gaacccacca caagatgggc
    20221 aataatcata ctgacaaatg gacgaaagac cgcttctttc caattccaaa taccgataac
    20281 tagcgaaatc gtaaagacag acaaactatc ccagggagcc ggaatataaa aggctccttc
    20341 ttgtatgaag cttgccattc ctacatatcc taaaacaact agaagaacta tagtcccaac
    20401 aacaatgtaa gtgccaattt tcattttagg agaatcttgg actaaacttc ttcgtaaaat
    20461 tgtggccaca agtccaaatc caatcagaaa aataagaagt tgccctaaaa atgtgagcaa
    20521 attgactgtt aagagaggac ctttagaaaa atcacttagt agttgataat aacgtaatac
    20581 cgccaggaca agaattggcg tcaaaaggga ctctttgata gaactgcgag gtgctccctt
    20641 gagaatctct ttcattattt ttttaggatt cttacctaga taatcctctg cactcatgcc
    20701 atctcgttct gcttctgaga aatctagcat catcaaatag atctgctctc tgagatagtc
    20761 ttcatcatag agaaatccag caagattaaa actttcccac aactcctcaa aatacttttg
    20821 attctcctca gaaaactcat gtagcaaagc gcttgtttct tcgtaatact tcattttctt
    20881 catggtttaa cccccattct taatcccttc tactttttga ctcaaatcgt cccattgttg
    20941 ccaaaagact gagacacgct cttctccttc tttcattaat gaaaaatact tccgatctgg
    21001 accatctggc gacgggcgca tgtcgcctct tatccattga tttttttcta acttttgcaa
    21061 caaaggataa atagttcctg gaacgatagt atcaaatcca gcctctcgca aagtctgaac
    21121 caactcataa ccataccgct ctttttgacc aatcatatcc aagacacaac cttcaagaac
    21181 accttttaat agctgagttt ctttcatcac ttctcccttc taatctattt tgtaatacct
    21241 actagtaact tcacctatag tatatcactt ctacactagt ttgtaaagca taatagttaa
    21301 tactcttcga aaatctcttc aaaccacgtc agcgtcgccc taccgtatgt atggttactg
    21361 acttcgtcag tttcatctac aacctcaaaa cagtgttttg agctgacttc gtcagtttca
    21421 tctacaacct caaaacagtg ttttgagcta acttcgtcag tttcatctac aacctcaaag
    21481 cagtgctttg atcaacccgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
    21541 aaataaaaaa acagaactag cctgaactag tcctgtctac ttttacccaa tcacacttcc
    21601 atttggtaca gctggatcaa ctgtgagaag ggttaatttg ccatcatgtt cagctgagag
    21661 aatcataccc tggctgacat attttttcat cattttacgt ggtttgaggt tagcaacgat
    21721 ttgaactttc ttgccgacca attcttgttc atttggatag tattttgcaa ttcctgaaag
    21781 aatctgacga tcttctccat caccagcatc caagcggaat tgaagcaact tatctgaacc
    21841 ttctacttta gacacttctt tgacttctgc gacacggatt tcaaccttgt caaagtcttc
    21901 aaacttgatt tcatccttgt ttagtttgag ctcaacttcg tccggattcc attctttttc
    21961 gactgctggt ttattgcctt ccatttgttc cttgatatag gcgatttctt cttccatatt
    22021 tagacgtgga aagataggtg ttcctttggc aactacagtc acatctgctg ggaagtcagc
    22081 caaactcaag ttttcaagac tagaaacttc ttccaaacca agttgagtca aaactgcacg
    22141 actagtttcc atcataaatg gttcaatcaa gtgagcaact acacgaatgc tggctgccaa
    22201 gtggctcatg acacttgcca attggtcacg aagagcttca tccttgtcca agacccatgg
    22261 tgcagtctca tcgatgtatt tattggtacg agagatcaga gtccagactg cttcaagcgc
    22321 acgtggatag tcaactgctt ccatgtgtgt atggaagtct gcgattgatt tttctgcaac
    22381 ctcagcaaga acatgatcaa attcagtcac accttctaca taggcaggga tttgtccatc
    22441 aaagtactta ttaatcatgg aaaccgtacg gttaaggagg ttcccaaggt cattagccaa
    22501 ttcatagttg atacgaccga catagtcttc aggagtaaag gttccgtctg aaccaactgg
    22561 aaggttacgc atgaggtagt aacgaagtgg atctagtcca taacgctcta ccaacatttc
    22621 agggtaaacg acattccctt ttgacttaga catttttccg tctttcatga caaaccaacc
    22681 atgggcaatc aaacgatcag gtaatttaac atccaacatc ataagaagga ttggccagta
    22741 gatagagtgg aagcgaagga tgtcttttcc taccatatgg aagactgttc cattccagaa
    22801 cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga gctgtcgcat agttaagaag
    22861 ggcatcaatc caaacgtaga caacgtgttt tggatttgat gggacaggca ctccccatgt
    22921 aaaggttgta cgagataccg ccaaatcttc caaacctggc tcgatgaagt tgcgtagcat
    22981 ttcattaaga cgaccatctg gcgtgataaa ttcaggatga gctttgaaaa attcgaccaa
    23041 acggtcttgg tatttgctaa ggcgaaggaa gtatgattct tcagaaaccc attcaacctc
    23101 atgacctgat ggagcaatac caccagtcac atttccagct tcatcacgga aaacttctgc
    23161 cagctggctt tctgtaaaga attcttcgtc tgatactgaa taccaaccag agtattcacc
    23221 caagtagata tcatcttgag caagtaagcg ttcaaagacc tgtgcgacaa ctttttcatg
    23281 gtagtcatcg gttgtacgga taaatttatc gtatgagata tctagtaatt gccagagttc
    23341 tttaactcca accgccattc catcaacata ggcttgaggt gtaataccag cttcttccgc
    23401 tttctgctgg attttctgac catgttcatc aagacctgtc agataaaata catcgtagcc
    23461 catcaggcgt ttgtaacgtg ctaggacatc acatgcgata gttgtgtagg cagaaccgat
    23521 atgaagtttc ccagatggat agtaaatcgg cgttgtaata taaaaatttt tttcagacat
    23581 aatttttcct ttccaggcaa atgaaacctg tttttctaac acttcattat atcacatttt
    23641 taatgaattt cgatagggaa atccatacaa aaacaagata gacgagtgtc catcttgttg
    23701 atctcattca taacgaaggg cttcaattgg atcaagtttc gatgccttgt tggctggcaa
    23761 gactccaaaa atcataccaa cactagccga aactgcaaga ctaaataggg caactgggat
    23821 tgatactcca acttctatac cttctattaa accttgcagt aacaaacctg ctaaggcagt
    23881 taaaccactt gcaattgtca agccaattaa gccacctaac aaggtcaaaa tcatggattc
    23941 aatcaaaaac tgaattaaaa tattggcacg tgttgcaccc aaagccttac gaagaccaat
    24001 ctcacgagtg cgctctgtca ccgaaaccag catgatgttc atgacaccag ttcctccaac
    24061 aaagagagaa atccctgcga tggaactaat aatcgtcgtc ataaaactaa acgattgttg
    24121 aatttctgca aatacaacgg actcatctgc cacctggtat tctccctgtt gtaagcctgc
    24181 aagctctgtc atttttcgtg ccagttctgg acccagagtt ggggttaaac tggtatcatt
    24241 cactcgaaag acaatactag ctatttcatc tatattaaaa ttcgcagcaa gggagatatt
    24301 ggtagtaata ggcaagccac caaacccata tatttttgac cttttagcct ccggactagt
    24361 ataaacccca atgacccggt aactaaatcc attgacttct acaaccttgt taatagcctc
    24421 ttgaggagat tcaaataaac taatggacaa ttcctcatct agcaaaataa cacttgcaaa
    24481 ctctttgaaa tcttgctctc tcagactacg acctgcaata atttcattct taacagcgtc
    24541 catgtaagtt ctgtttccac ctgtcaaatt agtattctca acctttttat cttgataggt
    24601 caagatggca ttcgttgaat tggttacata gtaactatcc actcccttca gtttagctgc
    24661 ctcttgaacc caggattctt gcggttttgg cggttcaaca ggaacttcct cttcctttcc
    24721 agaaaccgta aaagctgatt gtttctgagt aaaagaccca tctttacttt ttttaggaga
    24781 gaaaaagacg ctaatatttt tctgagattt agtcatatct ttattgactt gacgagatag
    24841 ggaatcaccc aaagccataa tcacaacaac tgatgaaaca ccgataataa tcccaatcat
    24901 agtaagcaaa gaacgcatct tgtgagccat gatagatgaa aaggcaaatt tcagattctg
    24961 catcttagtt ttcctccttt cctaactgag cactgtcaga cgaaatgacc ccatcccgaa
    25021 tgacaatctg acgtttggca taggcagcaa tctcaggctc atgcgttacc atgataatgg
    25081 tttttccttc tttattcaaa tcaaccaata attgcataat ttggttacct gttttggtat
    25141 ccaaggctcc tgtcggttca tccgctagga taatagaagg attgtttacc aaggcacgcg
    25201 caatggctac acgttgcttt tgaccaccag ataattctga aggtaaatgg tgactacgtt
    25261 ctatcaattc aaccttgtct aaatattcct cagccaactt gcgacgtttt gaagacgaaa
    25321 ctcctgcgta aatcaagggc aattctacat tttgcagagc attgagcttc gatagaagaa
    25381 agaactgctg aaagacaaaa ccgatttgtt ggttacggac cttagctagt tgtttttcac
    25441 caagcccagc cacttcttga ccttcaagat aatattctcc actggttggt gtatccaaca
    25501 tgccaatcgt attcatcaga gtggacttac cagacccaga tggtcccatg atggctacaa
    25561 attcaccctc attcacttct agattgatat ttttgagaac ctgcagttct tggtcaccat
    25621 tacggtaact tctgaagata ttttttagac taattagttg cttcatcagc cttcacctct
    25681 tttccttctt ccaaggaaga tgttggatta ctgatgacct tagcaccgtt cgttaaacca
    25741 gaagtgattt cttgattttc tgcgtcagca tttcccaatg aaacctcaac ttttttagcc
    25801 ttttgttgtt catccacaat ccagacataa tttttactat catccattac tagactgcta
    25861 acaggaacaa gaatagcctt agttttgctt ttaacctcaa tgttgacaga aaaaccttgt
    25921 ttcaaatcac caacctcgcc tgtcacatca atagtataag ggtatttaga acctgtatta
    25981 ttcccggctg ctggactagc tgcttcacca ttgtttttag gatagtcaga aatatagctt
    26041 aatttcccag tccatttttt atcaggatac actttagaag taaagcttac ttcttgacct
    26101 acagaaaggt tggctagatt gtactcagac aattctccct tgacttgtaa attttcattg
    26161 ctgacaatat gaaccataac ttgactcgcc cctgttggag atttagaaac attgctattg
    26221 acttcgacta cagttccctc tagggtactg agaacagttg ttgcatccaa ttgactttga
    26281 gccttgctta attgcgctgc agcatctgca cgcgcatcac gggcatcacc caattgagca
    26341 tcaatagaag caacagaatt tccagccact ggagttgggc tttgcaccgt tgcatcttct
    26401 cctcctactg gcgctggtaa ctgtggagcc tgagctgaag cggcttcatt tcgtgcttga
    26461 ttgagttcat tgatatgacg atctgcctta gctactgctc gactagctga atcataggcc
    26521 gcctgcgctt ctgaactact gtacttgact aaagcctgcc cttcgctgac cttatcgccc
    26581 acagaaacaa ggatttcatc taaatcaccc ttactagcat caaaataaac atattgttca
    26641 ttttttgctg ttactgtccc tgacaataaa acagaggatg ccacgcttcc ttccttggca
    26701 acaacaagat gagtaggctc atcttttaca gcagtctgag aaggttgtct aaaaagtaaa
    26761 atccccccgg cacccaatac aactacactc gcagcaccga ttgctgcata cagttgccac
    26821 tttttagctt taccattctt tttcttcata atgaaactcc ttttcttttt tacaatactt
    26881 tgctattata ccaaatttcc ctccagcaaa caatgcagtt cagatggaaa taatggcagt
    26941 tcaggattaa acaatcgttc ggaattttac ttttctattg tactagatat ataatacact
    27001 atcttgactt atttggcaag cttttttgca attttttgtg cgtagcagat ttttgcaatc
    27061 aaatcaaaaa aagaataaaa tataactatc aaaaaagaca ctctactatt taaaagatta
    27121 caaaggagtt ttcaatgaga gaatatgata tcattgctat cggtggaggt agcggaggaa
    27181 tcgctaccat gaaccgtgct ggtgaacatg gagccaaagc agccgttatt gaggaaaaga
    27241 aattaggtgg aacctgtgtc aacgtcggtt gtgttcctaa aaaaatcatg tggtacgggg
    27301 cgcaaatcgc tgagactttc catcaatttg gagaagacta cggctttaag actactgatc
    27361 ttaactttaa ctttgcaacc ctacgtcgca atcgtgaagc ctacattgat cgcgctcgtt
    27421 cttcttatga tggtagtttt aaacgcaacg gtgtagactt gattgaaggt catgctgaat
    27481 ttgtagattc tcatactgta agcgtaaatg gtgaactgat tcgtgctaaa catatcgtga
    27541 ttgctacagg tgcccatcca agtattccta atattcctgg tgctgagcta ggtggctctt
    27601 ctgatgatgt atttgcctgg gaagaacttc cagagtcaat tgccattcta ggcgctggtt
    27661 atatcgccgt tgaattagct ggcgtactcc acacttttgg tgtcaagaca gatctctttg
    27721 ttcgccgcga tcgtccttta cgtggttttg attcctacat cgttgaaggt ttggtcaagg
    27781 aaatggaaag aacaaactta ccacttcaca ctcacaaagt ccctgtcaag ttagaaaaaa
    27841 ctactgacgg cattaccatt catttcgaag atggtactag tcacacagct agccaagtta
    27901 tctgggctac aggtcgccgt ccaaacgtta agggattgca acttgaaaaa gctggagtga
    27961 ctctgaacga acgtggcttt atccaagtgg atgaatacca aaatactgtt gttgagggaa
    28021 tctatgctct aggtgatgta acgggcgaga aagaactgac tccagttgca atcaaggccg
    28081 gacgtaccct atctgaacgt ctctttaacg gaaaaactac tgcaaaaatg gattactcaa
    28141 ctattccaac tgttgtcttt tcacaccctg ctatcggaac tgttggtttg acagaagagc
    28201 aagctattaa agaatacggt caagaccaaa tcaaggttta taaatcaagc tttgcatcta
    28261 tgtactctgc ttgcactcgc aaccgtcaag aatcccgttt caaactcata acagctggtt
    28321 cagaagaaaa agttgtcgga cttcatggaa ttggctacgg cgttgatgaa atgattcagg
    28381 gatttgccgt tgctatcaaa atgggagcaa ccaaggctga ctttgatgca actgtggcaa
    28441 ttcacccaac tgcatctgaa gaatttgtaa ccatgcgtta atcgaaacaa aagaagctga
    28501 tataaatatg tctgcttctt ttttaatgat tttcgaatca acaaaaaaat tatccaactt
    28561 gactagtcac gaaaatcggc tgttacagtt tttgttacct tgtttttaaa aaatggttga
    28621 catcgactcc tatatgagta taatagttac tatacattag aaaagaggtt aactattttg
    28681 aaaaaagctc acgtttatgc tatccctgct attggggctg ctctcattgc tgctttggca
    28741 caaatcagtc ttccaattgg acctgttccc ttcactctgc aaaactttgc aattggcttg
    28801 attgctactg tctttagacc gagagaggct atactttctg ctggactcta tcttcttcta
    28861 ggtgctatcg gtcttcctgt ctttgcagga ggtggagctg gttttcaggc tttagttggc
    28921 cctactgcag gctatctttg gttttatctc gtttactctg gacttacttc ctctctaacc
    28981 aacagcaaga gtggtgttgt taagattttt cttgcaaacc tcttgggtga tgcccttgtc
    29041 tttgtcggcg ggattctcag cttgcatttc ctagctggaa tagcatttga aaaagctctt
    29101 gctgtggggg ttcttccttt tatcattcca gaccttggca aacttctggc tattagtttt
    29161 attagccgtc ccctacttca acgccttaaa aatcaggctt actttactaa ctaaaaaagg
    29221 atatcgagtt atcatgactc aatatccttt tcttttattt tgaaaactta tactcaatga
    29281 aaatcaaaga gcaaactagg aagctagccg caggctgctc aaaacactgt tttgaggttg
    29341 tggatgaaac tgacgaagtc agtaaccata catacggcaa ggcaaagctg acgcggtttg
    29401 aagagatttt cgaagagtat tagttgcctt taaaggcatc caccatcgtt tgaaattctt
    29461 catttgagag agtaatccct ttgcccattt tagtatggtc tggactccaa gcacgaatat
    29521 caaactttgc aggggcacca ttaaagctca cacggttaat ttccttggtc caaccttttt
    29581 cgttttcaga aagagtcaac aagtgctctt cgatttcaaa tgtaaattct gccattttct
    29641 tctccttttt tagtttcatt agtttattcg taaaatcttg tagattttag gaaaatttta
    29701 tataatattg atataaaaga agggaggcca atatgagaca taaattccag caagttctaa
    29761 ataaaataca tgatttttta aatggatatg accaacctga ccagactgaa accaactccc
    29821 ttacagccac tattgaagag gctatccaga aacaaaccgc tgttcacctt atcttgtctg
    29881 agacaagctt tacaggtgac atcatcaaat atgatcagca aggccagcaa attatcgtga
    29941 aaaatttttc caaaaatgtg agccggatta tccgtataag cgatattcaa cgcctgcgat
    30001 ttgtcccctc aactgtccaa acagcccaaa aaaatagatt taagaaagag tgagatgtag
    30061 ttgcttcatc ccactctttt tcttagcgaa tttgttcaaa atgtaaatga actgcaatat
    30121 gatctccata accacttctt tccaagtcac gttgtaaacg ataggaaatg tagtgttctg
    30181 caatggtaat gtaacctgcg cccaataaac gatgttcaac catagattga atcatactga
    30241 tagtcgcacg ttccaccttg gcttcttgta aatccaaaac taccttctta gtgacttgag
    30301 caagattttg acgcaaatca tctgtcaaaa cataaacagt ttgggctgcc ttcaagatgg
    30361 cttggtaaat cttatctgga ttaaattcag caatttcgcc attacgtttg attacttgca
    30421 taggtttctc ctttattctt tgttttcttt gatttctgcc agcatttttt cttcttctac
    30481 tgtcagttga taatgttcaa gtaaatctgg tctgcgctcg taggttttct ttaaactctc
    30541 gtacaatcgc cactgacgaa tcttttcatg gtggccactc atcaatacat ctggcacgac
    30601 catgcctcga taatcatagg gacgtgtgta ctgaggatat tctaaaagac ctgaagaaaa
    30661 actatcatct tggtggctag actccttgcc aatcacttct ggaatcaggc gaactgtagc
    30721 atcaatcatg gtcatagctg ccaattctcc accagtgagg acatagtcgc ctagggaaat
    30781 ctcatctgtt accaaggtct taatgcgctc atcataaccc tcatagtgcc cacagataaa
    30841 gattagctct tcctcttgag ccaaatcttc agcataagcc tgatcaaact gctttccagc
    30901 aggatcgagg agaataacgc gcggattttt cttttcaata gcatcaaagg aattgaaaat
    30961 aggttgtgct ctgagcaaca tgccctgacc gcctccgtag ggctcatcat ctacatgacg
    31021 ggccttttca gcattttctc gaaaattatg atactggata tccaagagcc ctttttctcg
    31081 agcctttcca acgattgagt gctccagtgg agaaaacatc tctggaaaga gggttaaaat
    31141 atcaatcttc atcgtctaac ccttctaaga tttccacatc gacccgttta tttggaatat
    31201 caacattgag aaccactggt gggatataag gtaaaagcaa atcacgtttg ccttttcgtt
    31261 tgaccaccca gacatcatta gcacctggtt gcaggatttc cttgatggtt ccaaccaagc
    31321 tatcaccctc atagacttcc aaaccgataa tctcgtgata gtaaaattca ccatcgtcta
    31381 ggtcattcaa atcttcctca gcgaccttga gactgtatcc cttgtacttt tcgatagtat
    31441 tgatatggta catatctttg aatttaataa tgtcaaagtt cttctgttta cggtggctag
    31501 cgatggtcac tgtttggaca aactgatctt tttcatcaaa caaagccagc tcagctcctt
    31561 ttttaaaccg ttcttctgca aaatccgtca cagacaagac tcgcatctca ccctgtaatc
    31621 cctgcgtatt aacgattttc ccaacattaa agtagttcat cttgtctcct gtaatctcct
    31681 tttttccatc ttattctgac aattctcgaa taatagccgc aattttttcc gattctgacc
    31741 attgtaaata atggtgattc cttcctaaaa tgagtttagt attggaagtc caatattctg
    31801 attctctgta ctctttttct ctataagtct gacaaaaaat aaatacaggg acatgagatt
    31861 ctatcgacaa attctcaaaa tcttcctcag taatctctcc agatatctga aattctggat
    31921 cttgattttc caactctaag cctttttctt gcattaattc ccagattttt ttattcgttt
    31981 caggactaaa tgttgcttga gttaagttct taaaataaag ttcaggacca cactcgtcaa
    32041 tcagcctcat ctgctcttcc atttctggat aaggattttc tgaaaaatca gcaaacatga
    32101 cttttttagt tgtcggttca attgctacta aagtctgacg cttaattggt ttctcgagta
    32161 atttgcaagc taaaattcca ctccaactat gtgcacaaag tatatattca gaaattccta
    32221 attcttcaag tacttcataa accgcatctg caagattatc tagatttttt ccagcttggt
    32281 catgaatcgg actcctacct gtgttcggaa aatcaattgt caaataacca attgtaggag
    32341 gaggtttttc aagtataagt gaaaaatttt cataacttgg tagcaaacct gctccgttta
    32401 gacaaactag cactttcttt tgcttttgat aagtaacaga gaggctacca atttctgtag
    32461 atacttcaaa cctcttcata aagaaatcca ctcattctat ataatgaatt attaaaaatc
    32521 cttatccttt attttatcac gttccaaaga ttttctcaag ttggaggaag gggacaacat
    32581 ctctactttc ccttcaagaa tccttccaaa tcatgtttat gttggtaatt aacggctgcg
    32641 gttttgtctt tctcaaagat ggttctagtt aggtcaatat gcttgatagc agcaatagcg
    32701 acggtgtagt gaatgatatc agccagttct atggcaggtt cctcgttcga atcctatccc
    32761 ttcttttcga ccagagcgcc tattcaaaac ctcggctact tctccgactt cctccactaa
    32821 cttcataaag agaccttcat cagtccgaga ctgctgttaa tgttcgagta agtagtcttg
    32881 gaattgccta aacgttcaat cttttatagt atattgaaac tagaatagta cacctttact
    32941 tctaaaacat tgttagaaat cgatttgact gtcctgatcg atttgtcctg ttattatttc
    33001 attttactat atcttctatt ccacacaaaa aagcgagaca tccgtcccgc ccttcttatt
    33061 tttcgtcaat aacgattctt acttttttgt attcagttgg gacagagtag acaatcgttc
    33121 ttatcgcaga aatagtgcga cccttacgac cgattacacg acccacatcg ctttgatcaa
    33181 gattcaaatg atattccaaa aattctggtg tatcttcaat cttgatagtt aaggcatctg
    33241 gttgtgaaat taagggtttc acaatcgcaa taatgagatt ttcaatcgta tccatctgtc
    33301 aacctacttt aaacttattt tgagaattta gaatcgtgga attttttcaa tacgccttct
    33361 tttgaaagga tgttacgtac tgtgtctgaa ggttgagctc cattagccaa ccatgcaaga
    33421 acgcggtctt ctttcaaagt tacttggttt tcagcaacaa gtgggttgta agttccaact
    33481 gtttcgatga aacgtccgtc acgtggtgaa cgtgaatctg ctacgttgat acggtagaaa
    33541 ggttttttct tagaacccat acgagtcaaa cggattttaa ctgccatttt taaagtctca
    33601 tttctttaat tttttatttc ggtgaaatag ctgagctatt tagcacatgt tctattatag
    33661 cagatttttg gcatgtgtca agaaaaaaac ttgacagact ataaatttct taaagtattt
    33721 agaaatttgt tagaatagga aataaatgtt tgaaagatac tatccgtgaa tactatttta
    33781 gaaaaatttt ataaagaaca ccaagtcaaa cccttcatat cgcctgaacg agatttggat
    33841 acttggctcc taagtcccaa gcccgttccc aagcgaaata tgaacttatt agcagatgat
    33901 tcactagcag gagatatcat tttactatgg agaatccagt ttggtacttt taccactgaa
    33961 acatgatttt aaaaactccc attcgaatat gattcaaaat tcgcttagaa tcaatgtttt
    34021 cccgcttttt caaaaaataa attttcatct aatttaaata actttcaatt aagtgtgaat
    34081 tttgcttaaa atcattaaaa agcaccccat ggtgtgaacc atgaagtgtt gtaaatgctg
    34141 tgttgtagct agttcttagc gtttagagaa ctggctagct ttacgagctt tcttaagatc
    34201 tggtttccaa aatactttga gtacacttat ggtattgatg cccctaaaca tctaaaaact
    34261 ctggtagaaa aagggtatgc tcttgtcgaa acttcttttg actcacttga ccatctaaat
    34321 actaccatga aaaagaatat cctgaagaag aagggagtta ctggactttc taaaatgaaa
    34381 tcttgcgacc tggatcaagc ccttcatgag catttttcag aagaagaatt agctggtcac
    34441 tttcatgtcc ttctatggac ttttttacaa tggcattgct atcacaccca atacctatct
    34501 aagcgcctgg ttcgtaaact ttattgcagc tcttcctcta aatttcctaa ttgttgaacc
    34561 aattgcccgt tttatactaa gttcttttca gaaaccattt actggggaag aagttgaaga
    34621 agttgaagat tttcaagatg atgatgaaat cccaactatt atctaagcca gttctgtaaa
    34681 ctactaatat ttgaaatcca cttcctttta gggtacaatg gtataaatga atttttgaga
    34741 ggatcagaat gaaaaaacta gcaacccttc ttttactgtc tactgtagcc ctagctgggt
    34801 gtagcaacgt ccaacgcagt ctgcgtggtg atgattatgt tgattccagt cttgctgctg
    34861 aagaaagttc caaagtagct gcccaatctg ccaaggagtt aaacgatgct ttaacaaacg
    34921 aaaacgccaa tttcccacaa ctatctaagg aagttgctga agatgaagcc gaagtgattc
    34981 tcaacacaag ccaaggtgat attcgcatta aactcttccc taaactcgct cctctagcgg
    35041 ttgaaaattt cctcactcat gccaaagaag gctactataa cggtattacc ttccaccgtg
    35101 tcatcgatgg ctttatggtc caaactggag atccaaaagg ggacggtaca ggtggtcagt
    35161 ccatctggca tgacaaggat aagactaaag acaaaggaac tggtttcaag aacgagatta
    35221 ctccttattt gtataacatc cgcggtgctc ttgctatggc taatactggt caaccaaaca
    35281 ccaatggcag ccagttcttc atcaaccaaa actctacaga tacctcttct aaactcccta
    35341 caagcaagta tccacagaaa attatcgaag cctacaaaga aggtggaaac cctagtctag
    35401 atggcaaaca cccagtcttt ggtcaagtga ttggcggtat ggatgttgtg gataagattg
    35461 ctaaggccga aaaagatgaa aaagacaagc caactactgc tatcacaatc gacagcatcg
    35521 aagtggtgaa agactacgat tttaaatctt aaaaaccaaa aaaatacagt atccacattc
    35581 ggtactgtat ttcttttact ctcattctta agttaaatta ttaaaatccc atatttggtc
    35641 tatccaacct tcataaaagt ctggatcgtg gcagaccata aggatagatc ccctgtattc
    35701 tttgagagcg cgtttgagct catcctttgc atccacatcc aaatggttgg tcggctcgtc
    35761 cagcactaaa acgttgtttt cacgattcat caagagacag aaacgaacct tggcttgctc
    35821 tccccctgat aatacttgaa tctggctttc aatatgtttg gttgtcaaac cacaacgggc
    35881 aagggctgca cggacttctg cttgattaag ggcaggaaag gcattccaga cagcttcaag
    35941 aggagtttgg cgattaccgc cttctacttc ctgctcaaaa taaccaagtt ctaaataatc
    36001 tccacgctcc acttccccag cgattggcga gataatgccc aagagactct tcaagagagt
    36061 tgtttttcca ataccattag caccaataat cgcaaccttt tgattgcgtt cgaaggtaag
    36121 atttaaaggc ttagtaagag gacggtcgta accaatttgc aagttcttgg cttggaagat
    36181 aaagcgccct ggtgtacgag ctggtttgaa atcaaaggat ggttttggtt tctcactttg
    36241 gagttcgata atatccatct tatccaattt cttttgacga gacatagcca tattacgagt
    36301 tgcaacacgg gctttattac gagccacaaa gtccttgagg tctgcaatct ctttctgctg
    36361 gcgttcgtag gctgcctcta gctgagattt cttcatagca taaacttctt ggaactggta
    36421 gtagtcacca gagtaacgcg tcagctgttg attttccaca tgatagacaa tattgataac
    36481 gtcattgagg aatggaatat cgtgcgaaat gagaacaaag gcattctcat agttttggag
    36541 atagcgcttg agccaatcaa tatgctcagc atccaagtag ttggtcggct cgtccaacag
    36601 caaaatatca ggcttttcaa ggagaagttt tgccaaaagc accttggttc tttgcccacc
    36661 tgacaaagaa gttacatccg tatccatgcc aaagtccata ataccaagag cacgcgctac
    36721 ttcgtcaatc ttagcatcca aggtatagaa atcacgactc tccagacggt cttgaagttc
    36781 tcccacttct tccatgagag catcaacatc cgcaccgtct tcagccattt ccatatagag
    36841 gtcattgata cgagcttcag ctttgaaaag ctcatcaaaa gccgtacgga gaacatcacg
    36901 caccgactgt ctttcagcaa ggacagagtg ctgatccaag taaccagccg tcacatattt
    36961 ggaccactca acctttcctt catctggcag cattttacca gtcacgatac tcataaaggt
    37021 tgattttcct tcaccattgg caccgaccag gccgatatgt tctcccttga ggagacggaa
    37081 ggacacatct tcaaaaattg cacggtcacc aaaaccgtga ctcagatttt taacttctaa
    37141 aatactcatt ttaattcctt atcttgtttt tatgtaatcg tttataaagg agccaagaca
    37201 gatagccacc caaagtgttg gtccacaaat catcaatctc aaagacgcga ttgaaatcaa
    37261 agaaaaagtc caagattaat tgcgtacact cgattccaag actcacaaga aaactaaaaa
    37321 gaaggacctt ttttgttttc cgcaaatttg gaaatagata aaggagttgg aaaatcagag
    37381 gaaaaaacaa gaagacattg aggatatttt gtaaaaaaat ccaacataat tgtccaatgt
    37441 cactcacttc gcccagtttc cagagagaat tgaaaggagt caaaagaaaa accaggcgtc
    37501 caagatgctg aatatctgga gttcccactc ccacggtaga ttgttcttga ggagtaaagc
    37561 aaaaatagac aatgcaaatg ctatagaaaa tgactcccca gaccaaaata tgattataag
    37621 tcttcttcat cattaaggat ttaccgctgc gactaccttc tggcggtcac gtttcattgt
    37681 gttaaagcgc aattgtccac aagctgcgtc aatatctgta ccatgctctt gacgaaccac
    37741 acagttgccc ccttttttct taagcgtatc atagaaagcc aacacgcgct ctttgggact
    37801 acggctatat tggtcatgct cactaactgg gttataagga atcaagttta cataagacaa
    37861 tttcttgatg ttcttgagca attcagccaa ttccaaggct tgttctacac cgtcattgac
    37921 ttcattaagc atgatatatt caaaggttac acgacggttt gttgtctcaa tgtagtattc
    37981 aatagcagca aagagttttt caatcggaaa ggcacggtta atcttcatga tacttgaacg
    38041 aagttcattg ttgggtgcgt gaagagacac ggcaagattg acctgaaccc cttcatcagc
    38101 aaagtcacga attttatgag ccaaacctga ggttgaaacc gtgatgtgac gagcaccgat
    38161 agccattcct ttatcatcat tgatagtacg aaagaaattc aagacattgt tgtaattatc
    38221 aaagggctca ccgattccca tgacaacgat atggttgacg cgttcatcct gaccacgctc
    38281 atcaaagtat ttctgaacca gcatgatttg cgctacgatt tcaccgttat tgaggtcacg
    38341 ctgcttctta atcaaaccag aggcacagaa ggtacaaccg atattacagc cgacctgagt
    38401 ggtcacacag acagataaac catagtgttg acacatgagt acaatctcaa ttaacatacc
    38461 gtcaggcaat tcaaagagat atttgactgt accatcagca gactcttgca caatacgttg
    38521 tttcaaggga ttgaccacaa actggtcatt gagcttagca atcaaatcct tggaaaggtt
    38581 ggtcatttct tcaaatgact gcacacgttt acggtagagc cattcccaga tttgatctgc
    38641 acggaatttc ttttctccct gctccaatac ccattcctgc atggtttgat gtgccaaact
    38701 atgaattgag ggtttcattt cttctcctta ttctctactc acttctgacg aatgacaaaa
    38761 tgacgttgtt ccttgtcctc tttctgagaa tgctggtctt tctgacgacg tctatttttc
    38821 ttatctgcat tcgactttcg tttagtttga gtcggtttct ttccttttct agaaggtgtt
    38881 tcttcttccg tcttacgcat tttcttgtca aatgatgctc gcttaggggc ttcattttct
    38941 aagacaaaat aggcacaacc ataactacaa tactctaaaa ggtagtcttg taaacgactg
    39001 attttttcaa gtttttcttc tgttcggtca tccttgtaaa aacctcgtag gcgaagctgt
    39061 tcgttgctcc agtcccccac gatataatca aacttggtta atacttctga aaaacgctga
    39121 ttaaaagtcg tcacatcaaa ggcatccttg atattttcaa ccaaggaaaa agctatccct
    39181 tccgtttcga ccttgtcccc gtgtaaatgg aactccggac caggaaactt gttatagttg
    39241 tataattcag gtgcaatttc ttttcgcata gatatccttt ttccacgatt acttaatact
    39301 ttattctacc ataatttcta gcagttagca cgtttctcat aaaaatgaaa aaagtctgac
    39361 gattttgtca gaccagaatc ttataaccta aaaaagagaa gaacaattct tccctccaac
    39421 tatcattatt tagcagctgc gtacaattca tctactttat tccagttgat tactgaaaag
    39481 aaagctttga tatagtcagg acgcacgttg cggtatttca cgtagtaagc atgttcccaa
    39541 acgtccaagc ccaagattgg ttttttacct tctgagattg gtgtgtcttg gtttgctgtt
    39601 gaagtcactt caagtttccc ttctttgttg acaaccaacc atgcccaacc tgaaccaaaa
    39661 cgagttgttg ctgctgcagt gaaggctgct tggaattctt caaatgaacc aaatgttgca
    39721 tcgattgctg ctgccagttc tgctgaagga gctgttttct cgggagtcat caattcccag
    39781 aaaagagcgt ggttcaagtg tccgccacca ttgttgataa gtgcttgacg gatatcagct
    39841 gggatagatt ctacatcagc aagcaaggct tcaaggtctt caccgatttc agggtgtttt
    39901 tctaaagctg cattggcatt gttgacataa gtttgatggt gtttgtcatg gtgcaaatgc
    39961 attgtttccg catcgatgta tggttccaaa gcgtcgtatg catatggaag ttctggtaag
    40021 ataatagcca tctgtaatac ctctttttct ttctatatga aaatgataac gcaaacattc
    40081 acttttttca agttttttgc ttatagataa ggaaatcact gacatacttt ctaataaaat
    40141 aagcaaatca gcaagaaacc cacgacaaga taatcctgac gcgggttgta gtttcaacaa
    40201 atgtcaattg acctgactag caatctgtaa gagtgccttt tcaaaaagga aacctttttc
    40261 ataaagacct gtcttaatct gatagtctgt ctcaatcaaa taggaaatag cttgcttcag
    40321 aaagctcaaa gaaagtcctc tcgaatctct taatgcaaac ttgatttgat aaggatttgg
    40381 gttacgtccc agataactac ctaaactact tgcaatctgc gattctgttt ggccagactc
    40441 tgccaaaatc ttcacctgag taaaagtccg aaattgtccc agcatgactg caatcagttt
    40501 gatttcatct tccccttgca aggtcaagtc tctcaccaaa tcgcgcgcct gatccatctt
    40561 tttagtcaga ataaactgag ttaaatcaaa aatattgtcc tgcaaggtct tgggaattgc
    40621 gttaacaata tcctcttcct cgataacaga atccgcctta taggactgta aaaagagaag
    40681 atttttctgg atttcgctaa attgaaaccc cgacttgatg aggagatttt caaaagaatg
    40741 attggtaaac tgcagacctt gtttctgact ccacttttgg aaatactggc gcaattcttg
    40801 ttcttttact tctactgcat cgaagacctt ggcatcacgc ttaagtaatt tgactaaccg
    40861 tcttttgcta tccagctttc cttctgcaaa gattatcaac ttggttgttg gagaaggatt
    40921 gtcaaggtat tcctcaaatg acttaagctc atcatctgtc aaaaagcgtt tcttagcagt
    40981 cgtgatatcc ataaaataat ctaatatcac gattttctca tccgcaaaga aaggaaggct
    41041 gaccaactcc agttccacat ccttgtaaac tacttctttc atatcaaagt aggcaaagtt
    41101 gaggtcagca gaatcatacc caatctgttt caacacttga ctcttcatca cttcaaactg
    41161 accctgatct gtccctgtaa ataggctcag gctcggtaaa tttgataaag tcaacttctg
    41221 actttcttca atggctagca tcgtctctcc tttcttcaga tttttcgatt taatttagtc
    41281 aatatagcgc aatttcccac ggaaatcttc taagctctcg tagccttttt ccaccatgat
    41341 tgctttcagt tcattggtaa tgcggtcaaa agcactgacg ccttctttgt gaagggtcgt
    41401 tcccacctgc accatacttg ctccacagag gatgtgttca aaggcatctc gaccagtcag
    41461 aacgccacct gttccgataa tttggatttg aggatttaaa cgttgataaa aggcgtgaac
    41521 attggctaga gcagtcggtt tgatgtattc tccaccaatt ccaccaaaac cattcttagg
    41581 ccgaataacg acagattcgt cttctatata gaggccgttt ccgatagagt taacgcagtt
    41641 gacaaacttg agcggatatt tgttgaaaat agctgccgct tgatcaaagt gaacaatatc
    41701 aaaataaggt ggcaatttaa ttccaagagg tttggtgaag taagcaaaca cttctgccaa
    41761 aatccggtct gttgtctcaa aatcataggc aatctgaggt ttacctggaa catttggaca
    41821 ggaaagattt agctcagtca gaccacgaaa atcactctct tggacttttt tcaaaatagt
    41881 atgggtttcc tctggagaca tgccgaccag agataagaag aaagttcggt tcgactcttt
    41941 ttcctgcaaa tctaaaagat aatccaaata atagtctaag ccattatttg gcaagcccat
    42001 agagttgatg gaaccaagtg gaacatcttg gtagcgtggc tcaggattcc cctgacggaa
    42061 gtccaaggtc gctgtcttag taacaaaggt tcctgccgct gagtttttga cctcttctaa
    42121 ctcctctatc gtcatacaag ccacacctgc tgcattcatc aagcaattgt caaactcaaa
    42181 accagcaatt tgtgttttcg ttgataccat gattctaatc ctccagattt cttttattgc
    42241 taatattata ccataatttt aattctaggt ttactagatt ctgtggttct atctatttat
    42301 tcggaaaaga aagtctagta cagaagtcat gctatggaaa cagctagtgt attagaagtt
    42361 tgaacaaggc ttgggtaaca gacttttgaa tgaagtccaa gcaacaagga gaaatctcaa
    42421 ccatgagtcc attccatgac tctgttgctc tagaaaacct tgcaatagtc aagtgataac
    42481 gaataaaact ttggattgaa atatccccaa gattatctat tacgaggaga aatcttaacc
    42541 tttataattt ttaaagaaat atagtaaaat gaaacaagaa caggagaaat cgatcaggac
    42601 agtcaaattg attgctaaca atgttttaga agttgaggtg tactattcta gtttcaatct
    42661 actatacatg taaatctcta ctttcgcaaa atggattttc agaacagtat cccagtatag
    42721 ttaaaaacta taaaaaagag aggacgttcc cctcttaaaa tcttatttta ctgcttcttt
    42781 caaagcatct accttatcca aacgttccca tggaagatca atatctgtac gtcccatgtg
    42841 accgtaagcc gatgtttgac ggtaaattgg acgcttgagg tccagcattt ggataatccc
    42901 tgcagggcga aggtcaaaga tttgacgagc cgctttttca agttgacttt cagctactgt
    42961 tcctgtaccg aaagtatcga tacgaacaga aacaggttgc gcaacaccga tagcataggc
    43021 caactgcact tctgccttct tagcaaggcc tgctgcaacg atattcttgg caatatagcg
    43081 agccgcataa gaggctgaac gatccacctt agtcgcatct ttaccagaga aggcaccacc
    43141 accatgacga gagtagccac cataagtatc tacaataatc ttacgaccag tcaaacctga
    43201 gtccccttga ggaccaccga ttacaaaacg acctgtcgga ttgataaaga attttgtctt
    43261 atcatcaaga taagaagatg gaataacttc tttgatgacc ttgtcaatca catcttgatg
    43321 gatttgttca ttagtggcct ctggatcatg ctgagtagaa ataacgactg tatctacacg
    43381 taccggacgg tcattttcat cgtactcaac tgtaacttgt gattttgcat ctggacggag
    43441 atagctaatt tctccagact tacgaagttc tgccagacga cgaatcaatt tatgactgag
    43501 tgcaattggc aatggcataa gctcttctgt ttcatctact gcaaatccaa acatgagccc
    43561 ttggtcacct gctccaatca agtccagtgg atcttgatca gcatttccac gaacctccaa
    43621 ggcttcgtta acaccttgag cgatgtcagg agattgttcc accaaagatg ggtgtactcc
    43681 caccgtctca gcagaaaatc catattctgt attggtataa ccaatctctg caatggtatc
    43741 acgaaccaca cggttaatat ccacataggc atttgtagaa atttcaccaa aaacgtggac
    43801 agaaccagta tatacagctg tttcagcagc aacgtgcgcc tctggatcct ttgctaaaat
    43861 agcatccaaa atcgcatctg aaatttggtc tgcaatctta tccggatgcc cctcagatac
    43921 agattcagac gtgaataatt tacgctctga cataaaaatg tcccccctta aaaaatattg
    43981 ttatagagtt acaaagtact gataggaaaa ctcttcgtaa taaataccta ccatcttatc
    44041 gggactatat aactttatca ttataccatt tttaatcgca atttgcagtc tttaatgtag
    44101 tatttcggtt tagatagttc gttctcataa agcaaaaagt tggagctcag tactccaaca
    44161 atttctatta aaatgtttga cgtttagctt tacgctctgc acgaccgcga gcgcgatttt
    44221 cagcacgctt ggttttacgg cgcttttcat caaccgccca ttgaattttc ttcttataac
    44281 ccggtttgac ttttttcttt ttctttttaa ccaaaccaat catttcgata tcaagtttat
    44341 cttgtttttt ctcacggttg gcacgacgat cacggtcata ggtatcttga aattccccgt
    44401 ctttgaccat cttaggacta aacttgattc ccaatttctc caactcacgg atatccgagt
    44461 catcacttgg ctgataaagg gtaatagctg tacctggtag gccatttcgt ccagtacgac
    44521 caacacggtg aacaaaaaaa gataagtctt gcggaatggc atcattgatg acatggctga
    44581 caccttcaat gtcaatccca cgtgctgcca aatctgttgc gacaatatac tcaaaatcca
    44641 gattttgcac ctgattcatg attcgcttgc gttcacgagg ggcaatatcg ccatggattt
    44701 ttgcaacctt caagccttga gcagtcagat atgaatgcaa ttcatcagca cgcgttttag
    44761 tgttaacaaa aatcattgcc aaatacggct gcatcaactg agtcaactgg taaatttgag
    44821 cattcttatc atgtcccttg gtcgaaatca accaattatc aatggtgtca gaaataaccg
    44881 ttttggtctt aattttctcc ataacaggat tggataagta ttttttcaag aatggttgca
    44941 gtttttgtgg gacagtcgct gagaagacca tgaattgcaa gtcttttgga agactgccag
    45001 caatcttatc aacagtttcc aagaatccca tatccaaggt catatccgct tcatcaacaa
    45061 caaatgtctt ggctttatga atagctaaat caccagattt aaccaagtcg tagatacggc
    45121 ctggtgttcc aataacaata tgaggctgat tgcttgccaa tttctcaatc tggcgagcct
    45181 tatccgtacc acccacataa ttaaccacac gaacttcgac atctgagtga gctgaaatct
    45241 gacgcgctac ttggtaaatt tgagtagcca actcacgact cggtgcagta atcactgctt
    45301 gtacactatc gctagcttca tctaattgct ggaaaatcgg taacaagaaa gtatgagtct
    45361 tacctgaacc tgtttttgat tctcctacta ggtcacgacc tgccaaaaca ataggaatca
    45421 acttgtcttg cacctctgtt ggagttgtaa attttaactc ctccaaggct tctctaatat
    45481 agtttttaaa ttgaaatttc gtaaatgaca taacatcctc gattctatct atcttatcaa
    45541 ttataccata ttttattcca ttacagtagt ctcacttatt taggctattt ccagtagctt
    45601 ctctagtaag aaaaggctgg aattttatag ttccaacctc ttttcagtta ttatttccag
    45661 tttaacatag cattcaagcc atagtgatca ctcacttgtg gactcttgtt accatcaaat
    45721 acgacatgta aattttccac cgctaactct ttggtagtaa agacataatc gattcgaagg
    45781 ggttcagtgt tccctttcca gccatcaatt tcaggcggaa cagtatagct accacttttc
    45841 tcttgagcaa cttcaaatgc gtcttgtaag cctaatggac tagctaaaat agcttggtaa
    45901 ccttcctgac ctgctgggtt gttaaaatct ccagctagta aaagtggctt gttcaatttt
    45961 ttcaagacag cctcaaatcg tgcccattct tcttgaaaac ctttatccca ccaagagaga
    46021 tgaacactgg caactgctag ctccttgcca tcgactacag tttcagctag ggcaacacgg
    46081 cgagtatgat agtctgttgg atcatccaca tctgaaacca aaatttctct ggcttcaata
    46141 ggtgttttag acaagatagc cacaccttcg tggtagcggt catagccgat atggttatag
    46201 gcccaggtcc agtagtaatt tttcccttgc tcagataact tttcaaccaa gagtctaaca
    46261 tagtgatctt ggtgaatagg ctcagctgct ggcaaagctt gataaaggtc attaacctcc
    46321 acctctgacg aggtcatctc ctgattaatt tcttggaaac aaatcaaatc atagtccttt
    46381 tcaagaatat cttcaagcaa aatctggaat ttttcctctg cttctttctc catccaacta
    46441 tgagtattga gtgttaaaaa tttcattctt ttctcccaaa ataagaggtt ggaatacagc
    46501 ttccaacctc aagtatatta caattctact ttagcaactg ctgttttagc tgcaagagaa
    46561 cctgtttttt ctaatttaac tgatttaatt gcatcaccat ttgtgaagac aactactgtt
    46621 gaagtttcac gtcctgctgc acggatagca ttcaagtcag ctgtaacaag gagatctcct
    46681 gctgcaactt tttgtccttc agcaacatga actgtaaatg gtttaccttc aagacttact
    46741 gtgtccaaac caatgtgaac caatacttca agacctgctt ccgtcacaat accaaaagca
    46801 tgttttgttg ggaagatgct tgatacagta cctgaaactg gagatacaat gtttccattt
    46861 gcaggttcta ctgcaaatcc atcacccatc attttttgag caaatactgg atcctttact
    46921 tgttccaaag caacaacttg accgtctgct actgagtaaa cttcctcagt aagatctttg
    46981 aagtgaacag tgttttgttg tacttcagtc atttggcttg gaagagtttc aggaatgatt
    47041 tcacctgaat caaggatatc ttggatatca gatttcaaaa tgtcagcttt tggaccgtag
    47101 atagcttgaa ccccttgtcc tttcatcaca agacccatag ctccttctgc tttccattgc
    47161 tctgcatttc ctactttatc tgcatcttta acagttacac gaagacgagt catacatgca
    47221 tcaacatcaa cgatgtttac acgtccacca agaaggttga taatgtttac agcttgagag
    47281 cctgctgcaa ctttcacttc gctgctggtt tcttctgaac cttcagcagt ttcgtagttt
    47341 ccgttgcgcc ctggagttgc gtagttgaat ttttgaatca tgaagtttgc gataaagtac
    47401 atgattacag caaagagaac agttacccaa acgaagttaa cgatatccat accaatacca
    47461 gcactgattg caataggtgt acgagtcaag aactcgattg aaccgaatga gtgcatacgt
    47521 aggtttacga cgtcagccat agcgaaggca gcaccttgaa caagtgagta aacaagatac
    47581 ataggtgttg cgatgaacat gaacatgtat tcgattggtt cagtaacccc tgtcaagaat
    47641 gttgcaagag ctgttgcaat catcatacct ttgtatttat gtttcttgtc agcatcaaca
    47701 ttacggtaga tagcaacaat cacacccatc aagataccga atgaaccgat catttgtcca
    47761 actttgaaac gagctggatg tactgtatct aacaagtgtt ggtattgact agcatcagta
    47821 cctttaaggt ttacaaggtc tgttacccat gcaagccata gtgggtcttg accgaatact
    47881 tgagtacctt tagctgcacc agttaaaatg tcataagtac caccaagagc tgtgtagttc
    47941 attgggatag tcaacatgtg gtgaagacca aatggcaaga gcaaacgttc caaagtacca
    48001 tacaagaatg gtgcaagaat tggagcagtt tcttgtgagt tggcaatcca gataccgaaa
    48061 ttattgatac ctgtttgaac tactggccag aaagcagcaa gtagaattgc agcgattgct
    48121 gaacgaagaa taactacaaa tggtacgaaa cgtttcccgt tgaagaatga aagtgcatca
    48181 ggaagtttac ggaagttgta gtatttgttg taagcagttg cccctacaaa acctgagata
    48241 atccctacga atacccccat gttcaaggct ggagcttcaa gaacactgat aaagtaagca
    48301 gcaactttga ttgaaccacc aaagaaagta gttaccatag catctggatt tttcaacata
    48361 tcgcctgata caccaaagat tgtaccagtg atacggttaa tcaagatgaa ggcaagacca
    48421 gcggcgaaag caccaccagc acgttcttta gcccagcttc ctccaatggc tagggcaaac
    48481 aaaatgtgaa ggttaccgat aaccccccaa ccgatttgct caagaattcc acctgtgatg
    48541 acaagtggtg caaaggttgg gttaatcatc acgatagact taccgattga aatcatcaaa
    48601 ccagcagccg gcataaccgc gataactacc atcaaagcct taccgaattt ttgccaaaat
    48661 tcgaaagaca agacattttt gaatgtatct ttcatcattc aaatctcctt tatttttatt
    48721 taggcaaacg ttttacgaaa acgtttgcac tttctatgat ttaattatac cactttaatt
    48781 ttttttgtaa aggcttttat aaaaaaatta cacttttttc taaaaaattt
//
LOCUS       DAVKMO010000009        48450 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVKMO010000009 DAVKMO010000000
VERSION     DAVKMO010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48450
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.009"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..803)
                     /gene="cbpJ"
                     /locus_tag="VW361_000607"
     CDS             complement(<1..803)
                     /gene="cbpJ"
                     /locus_tag="VW361_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEU9743711.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGMRLEGFPNS
                     EWYYFDKNGVLQEFVGWKTLEIKTKDSVGRKYGEKREDSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYLGGERRAGWINDDLTWYYLDPTTGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRS"
     gene            complement(822..1844)
                     /gene="cbpC"
                     /locus_tag="VW361_000608"
     CDS             complement(822..1844)
                     /gene="cbpC"
                     /locus_tag="VW361_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU9743712.1"
                     /translation="MKLLKKMMQVALAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYSLSAEKRTYYFDNNYAVKTGWIYE
                     EGHWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDASGKML
                     TDWQKVNGKWYYFGSSGSMATGWKYVRGKWYYLDNKNGDMKTGWQYLGNKWYYLRSSG
                     AMVTGWYQDGSTWYYLDAENGDMKIGWTKVNGKWYYLNSSGAMVTGSQTIDGKVYNFA
                     SSGEWI"
     gene            complement(1943..2632)
                     /locus_tag="VW361_000609"
     CDS             complement(1943..2632)
                     /locus_tag="VW361_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9743713.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(2644..4068)
                     /gene="gndA"
                     /locus_tag="VW361_000610"
     CDS             complement(2644..4068)
                     /gene="gndA"
                     /locus_tag="VW361_000610"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU9743714.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(4144..5538)
                     /gene="mapZ"
                     /locus_tag="VW361_000611"
     CDS             complement(4144..5538)
                     /gene="mapZ"
                     /locus_tag="VW361_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU9743715.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSLSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(5551..6708)
                     /locus_tag="VW361_000612"
     CDS             complement(5551..6708)
                     /locus_tag="VW361_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU9743716.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(6793..7173)
                     /gene="rnpB"
                     /locus_tag="VW361_000613"
     ncRNA           complement(6793..7173)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VW361_000613"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(7194..7523)
                     /gene="gpsB"
                     /locus_tag="VW361_000614"
     CDS             complement(7194..7523)
                     /gene="gpsB"
                     /locus_tag="VW361_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU9743717.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(7593..8120)
                     /locus_tag="VW361_000615"
     CDS             complement(7593..8120)
                     /locus_tag="VW361_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU9743718.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            8186..8782
                     /gene="recU"
                     /locus_tag="VW361_000616"
     CDS             8186..8782
                     /gene="recU"
                     /locus_tag="VW361_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU9743719.1"
                     /translation="MVNYPHKVSPQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLLAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            8779..10938
                     /locus_tag="VW361_000617"
     CDS             8779..10938
                     /locus_tag="VW361_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU9743720.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWNSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(11104..16407)
                     /locus_tag="VW361_000618"
     CDS             complement(11104..16407)
                     /locus_tag="VW361_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU9743721.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQERVKTEDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HYPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EVGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTSLVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWGGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTTTDWPDNNKSKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKTPDYKQEID
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(16708..17796)
                     /locus_tag="VW361_000619"
                     /pseudo
     CDS             complement(16708..17796)
                     /locus_tag="VW361_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein"
     gene            17796..18353
                     /locus_tag="VW361_000620"
     CDS             17796..18353
                     /locus_tag="VW361_000620"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9743722.1"
                     /translation="MIKCLFPNAQIVLDRFHIIQHLSREMMTTRIVIMKNFDKQSLPY
                     RAMKNHWRIFQKDSRKLSDKAFYSRTFRQTLTPREIVNKTLAFSDELHYYDDLYQLLL
                     FHLQEKNADHFFDLLTEAFPQLNQAFRTALSTLVRYRKYVTNTIQMPYSNSKLEAINK
                     LISLLQTQTCRYGYVFLQILEFSQR"
     gene            complement(18280..19497)
                     /locus_tag="VW361_000621"
     CDS             complement(18280..19497)
                     /locus_tag="VW361_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU9743723.1"
                     /translation="MNCIESYQKWLNVPDLPAYLKDELLSMDDKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIYVVRQATEGLAKLVESKGETAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMLPADADALTDYIRAIDNPFAVALADLEEAKSTGLIEVIGETLDSAYLEEVKSVNI
                     NQDLIDQYGRDMKIVYTPLHGTGEMLARRALAQAGFESVQVVEAQAKPAPDFSTVASP
                     NPESQAAFALAEELGRQVDADVLVATDPDADRLGVEIRQADGSYWNLSGNQIGALIAK
                     YILEAHKQAGTLPKNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMFGFEEG"
     gene            complement(19494..20414)
                     /gene="galU"
                     /locus_tag="VW361_000622"
     CDS             complement(19494..20414)
                     /gene="galU"
                     /locus_tag="VW361_000622"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU9743724.1"
                     /translation="MKKVKKAVIPAAGLGTRFLPATKALAKEMLPIVDRPTIHFVIEE
                     ALRSGIEDILVVTGKSKRSIEDYFDSTFELEYSLRKQGKMELLKSVNESTDIKVHFVR
                     QSSPRGLGDAVLQAKSFVGDDPFVVMLGDDLMDITDSTAVPLTRQLMDDYNATQASTI
                     AVMPVRYEDVSSYGVISPRLESSNGLYSVDAFVEKPKPEEAPSNLAIIGRYLLTPEIF
                     SILETQKPGAGNEIQLTDAIDTLNKTQSVFAREFVGKRYDVGDKFNFMKTSIDYALQH
                     PQIKESLKNYVIALGKQLEKLDDCSSSGHL"
     gene            complement(20712..21965)
                     /locus_tag="VW361_000623"
     CDS             complement(20712..21965)
                     /locus_tag="VW361_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000287926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9743725.1"
                     /translation="MYTFILMLLDFFQNHDFHFFMLFFVFILIRWAVIYFHAVRYKSY
                     SCSVSDEKLFSSVIIPVVDEPLNLFESVLNRISRHKPSEIIVVINGPKNERLVKLCHD
                     FNEKLENNMTPIQCYYTPVPGKRNAIRVGLEHVDSQSDITVLVDSDTVWTPRTLSELL
                     KPFVCDKKIGGVTTRQKILDPERNLVTMFANLLEEIRAEGTMKAMSVTGKVGCLPGRT
                     IAFRTEILRECIHEFMNETFMGFHKEVSDDRSLTNLTLKKGYKTVMQDTSVVYTDAPT
                     SWKKFIRQQLRWAEGSQYNNLKMTPWMIRNAPLMFFIYFTDMILPMLLISFGVNIFLL
                     KILNITTIVYTASWWEIILYVLLGMIFSFGGRNFKAMSRMKWYYVFLIPVFIIVLSII
                     MCPIRLLGLMRCSDDLGWGTRNLTE"
     gene            complement(21981..23165)
                     /locus_tag="VW361_000624"
     CDS             complement(21981..23165)
                     /locus_tag="VW361_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU9743726.1"
                     /translation="MKIAIAGSGYVGLSLAVLLAQHHEVKVIDVIKDKVESINNRKSP
                     IKDEAIEKYLVEKELNLEASLDPAHVYKDVEYAIIATPTNYDVDLNQFDTSSVEAAIK
                     TCMEYNDTCTIVIKSTIPEGYTKEVREKFNTDRIIFSPEFLRESKALYDNLYPSRIVV
                     GTDLDDSELTKRAWQFADLLKGGAIKEEVPILVVAFNEAEVAKLFSNTYLATRVAYFN
                     EIDTYSEVKGLNPKTIIDIVCYDPRIGSYYNNPSFGYGGYCLPKDTKQLKASFRDVPE
                     NLITAVVQSNKTRKDYIAGAILAKQPSVVGIYRLIMKSDSDNFRSSAVKGVMERLDNY
                     GKEIVIYEPTIECDTFMGYRVIKSLDEFKNISDIVVANRMHDDLRDIQEKLYTRDLFG
                     RE"
     gene            complement(23343..23759)
                     /locus_tag="VW361_000625"
                     /pseudo
     CDS             complement(23343..23759)
                     /locus_tag="VW361_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
     gene            23783..24238
                     /locus_tag="VW361_000626"
                     /pseudo
     CDS             23783..24238
                     /locus_tag="VW361_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
     gene            complement(24307..24724)
                     /locus_tag="VW361_000627"
                     /pseudo
     CDS             complement(24307..24724)
                     /locus_tag="VW361_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase"
     gene            complement(24734..25426)
                     /gene="cpsC"
                     /locus_tag="VW361_000628"
     CDS             complement(24734..25426)
                     /gene="cpsC"
                     /locus_tag="VW361_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU9743727.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKSGLTNQDLQAGSYLVKDYREIILSQDVLEEVISDLKLD
                     LTPKGLANKIKVTVPVDTRIVSVSVNDRVPEEASRIANSLREVAAQKIISITRVSDVA
                     TLEEARPAISPSSPNIKRNTLIGFLAGGIGTSVIVLLLELLDTHVKRPEDIEDTLQMT
                     LLGVVPNLGKLK"
     gene            complement(25435..26165)
                     /locus_tag="VW361_000629"
                     /pseudo
     CDS             complement(25435..26165)
                     /locus_tag="VW361_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
     gene            complement(26167..27373)
                     /locus_tag="VW361_000630"
                     /pseudo
     CDS             complement(26167..27373)
                     /locus_tag="VW361_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
     gene            27551..28079
                     /locus_tag="VW361_000631"
                     /pseudo
     CDS             27551..28079
                     /locus_tag="VW361_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(28072..28245)
                     /locus_tag="VW361_000632"
     CDS             complement(28072..28245)
                     /locus_tag="VW361_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU9743728.1"
                     /translation="MNIKKRVLGAGLTFASALLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYADNIVN"
     gene            complement(28404..30011)
                     /locus_tag="VW361_000633"
     CDS             complement(28404..30011)
                     /locus_tag="VW361_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU9743729.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDELIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPMQEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            30163..31647
                     /locus_tag="VW361_000634"
     CDS             30163..31647
                     /locus_tag="VW361_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU9743730.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYTGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKISRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            31742..32224
                     /locus_tag="VW361_000635"
     CDS             31742..32224
                     /locus_tag="VW361_000635"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU9743731.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(32520..34625)
                     /locus_tag="VW361_000636"
     CDS             complement(32520..34625)
                     /locus_tag="VW361_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9743732.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRTTGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTCGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQVAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(35234..36214)
                     /locus_tag="VW361_000637"
     CDS             complement(35234..36214)
                     /locus_tag="VW361_000637"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU9743733.1"
                     /translation="MFIFISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLFTSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKIFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(36216..38468)
                     /gene="pbpX"
                     /locus_tag="VW361_000638"
     CDS             complement(36216..38468)
                     /gene="pbpX"
                     /locus_tag="VW361_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU9743734.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(38472..38789)
                     /gene="ftsL"
                     /locus_tag="VW361_000639"
     CDS             complement(38472..38789)
                     /gene="ftsL"
                     /locus_tag="VW361_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU9743735.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(38801..39751)
                     /gene="rsmH"
                     /locus_tag="VW361_000640"
     CDS             complement(38801..39751)
                     /gene="rsmH"
                     /locus_tag="VW361_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU9743736.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            39917..40111
                     /locus_tag="VW361_000641"
     CDS             39917..40111
                     /locus_tag="VW361_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9743737.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            40127..40669
                     /locus_tag="VW361_000642"
     CDS             40127..40669
                     /locus_tag="VW361_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU9743738.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            40680..40922
                     /locus_tag="VW361_000643"
     CDS             40680..40922
                     /locus_tag="VW361_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743739.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            40933..41268
                     /locus_tag="VW361_000644"
     CDS             40933..41268
                     /locus_tag="VW361_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743740.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(41378..42379)
                     /locus_tag="VW361_000645"
     CDS             complement(41378..42379)
                     /locus_tag="VW361_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9743741.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(42439..44340)
                     /locus_tag="VW361_000646"
     CDS             complement(42439..44340)
                     /locus_tag="VW361_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU9743742.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGMHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(44362..44655)
                     /locus_tag="VW361_000647"
     CDS             complement(44362..44655)
                     /locus_tag="VW361_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9743743.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(44655..45473)
                     /locus_tag="VW361_000648"
     CDS             complement(44655..45473)
                     /locus_tag="VW361_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9743744.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(45460..46239)
                     /locus_tag="VW361_000649"
     CDS             complement(45460..46239)
                     /locus_tag="VW361_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9743745.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(46254..46745)
                     /locus_tag="VW361_000650"
     CDS             complement(46254..46745)
                     /locus_tag="VW361_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9743746.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKVALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(46755..47945)
                     /locus_tag="VW361_000651"
     CDS             complement(46755..47945)
                     /locus_tag="VW361_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEU9743747.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELAHHDLGFLYTPSCMAEYKINEDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGMTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(47957..48391)
                     /locus_tag="VW361_000652"
     CDS             complement(47957..48391)
                     /locus_tag="VW361_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9743748.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
BASE COUNT        14187 a        10853 c         8479 g        14931 t
ORIGIN      
        1 gaacggagat agtaccattt gttcccaagg ttttgccaac ctgttttcat atcgccattt
       61 ggctggtcta aataatacca agtggtacct tcctgatacc agccagtggc cattgctcct
      121 gaggaacgga ggtagtacca cttattacct agatattgcc aacctgtttg cataatacca
      181 gttgttggat ctaaatagta ccaagtcaaa tcatcgttta tccaccccgc acgtctttca
      241 ccaccaaggt agttttctcc attaatttcc gtcttagcta gataatacca gttagactga
      301 tcataaagcc aacctgtctc taaagaatga ttttgattaa agtaatagtt cgtataataa
      361 cgtttctctt ctttatcttc tgaatcttca cgtttttccc cgtactttct tccaacactg
      421 tctttagttt taatctctaa tgttttccaa ccaacaaact cttgtagcac tccattttta
      481 tcgaagtagt accactctga atttggaaaa ccttctaatc tcataccatt tgggtaagga
      541 ccaattgtac tacctttaga tggaaacggg atatattgcc agccgacaac catctctcca
      601 gatagagaat caaaataata gtacttacca tcaatcactc gccagtaggt ttctttgagg
      661 tccccctttt tgtaataggt tctaccgttt tcttggacaa actgccatcc ttcagagtta
      721 tctgcaaata ctgtattcgt agctagcaaa ccaaagaaaa ttactgttag tccagcttgc
      781 atagtttttt tcaaaagctt cattttatat atcctccaac attaaatcca ctcaccagat
      841 gaagcgaagt tataaacttt accatcgata gtttgactac ctgtaaccat tgctccagag
      901 gaattgagat aataccattt tccatttact tttgtccaac ctattttcat atcaccattt
      961 tcagcatcta aatagtacca agttgaacca tcttgatacc agccagttac catagctcct
     1021 gatgaacgga ggtagtacca cttgttacca aggtattgcc atcctgtttt catatcacca
     1081 tttttattat ctaagtaata ccatttgcct cgtacatatt tccaacctgt tgccatagaa
     1141 ccagaggagc caaaataata ccattttccg tttacttttt gccaatctgt aagcatctta
     1201 cctgaagcat ctaggtagta ccatggagca ggtttgcttc tatcaatgtc aatagtaaca
     1261 tgaaaatctt gagtccaacc cttagcaact tcaccaattg gtagtggatt gtaagaatca
     1321 tcgccaaaat ttcctagctt atttaaataa taccaatgac cctcttcata aatccagcct
     1381 gtctttacag cataattatt atcaaaataa taagttctct tttcagcaga tagagaatat
     1441 tgttcaccgt atacttttcc tgtattttca gacgtttttg cctctagtac ttgtttatct
     1501 gtttgttcta gcaaagcacc atcttgtcca aaatagtacc acttctcctg aaggccaatt
     1561 tcattaactg gttggttatc gaataaatta tcacgataac ctgttccagg aatttctaag
     1621 tattgccaac cgacaaccat ctctccaata tcaccaaaat agtaagtttt accgtctatt
     1681 ttatgccaat agattgcttt atgatcatct tttacataat attttctatt atccttatca
     1741 acaaatcggc cacctgtggt attcgcaaat accgtatttg tagctagcaa accaaagaaa
     1801 aagactgcta atgcgacttg catcattttt ttcaaaagct tcattttata tatcctccta
     1861 aaacgattgt agtaaaaact agattgtatg tcaatatata aaaactcctc aaaaaagcag
     1921 ttacacaact gcaactgctt ttctattctt gcatggtata tccaacacca cgcacagttt
     1981 taatgtagct tttttggcct ttaacatcaa gcttgctccg tagatagcgg atatagacat
     2041 ctacgatatt tgtctcggtc gcactttcat acttccaaac actttccaac aattgctcac
     2101 gagtcaatac tttcttgctt cccataagtg tcgccaaaag gtcatactca cggcgggtca
     2161 gagcaatcat ctcttcacca cgataaaccg tgtgatgttc aacatctatc ctaagattgc
     2221 ggtaggtcct tggaactttc atcagactgc agtgttgatc aatgaagtcc cgacctcgga
     2281 agatcgccga aatacgcgct accagatttt cgataaggac tggcttatag atgtatgaaa
     2341 ctgcaaaacg ctgaacaact tccagctctt cttgcaagtc ttcccaatga tctaaaatca
     2401 tgatgactga ggcaggttta gttcggctca atttttctgc aaaatcctga gccatcatat
     2461 ctcccagatt aacattcaat aaaatcaaat catagtctgt ctgaagagcc atggagaggg
     2521 ctttttgccc ctcctctacc agatcaaccc gatactgctc tttctggagt tccaaactta
     2581 aaaaatgagc tagatttcgt tctttctcaa gtaataaaat ccgtttcccc atggctgacc
     2641 tacttatttt tcgtcatacc aagagtagtg gaaggttcct tctttgtctt tacgttggta
     2701 agtgtgagca ccaaagtagt cacgttgtgc ttggatcaag ttagctggaa ggtcagctga
     2761 acggtagcta tcaaagtaag taatagctgc tgagaaagtt ggcactggca cacctgcttg
     2821 aaccgcaaga gctacgatat cacgtactgc ttgttggtac ttagcagtaa catccaagaa
     2881 gtactcgtcc aaaagaaggt tggcaagatc tgcatcgcgg ttgtaagcat ctgtaatctt
     2941 ttgcaagaaa cgagaacgga tgatacagcc atcacgccag atagatgcga tatctgcaaa
     3001 tggcaagttc cagttgtttt ctttagaggc tacacgcaat tgagcaaatc cttgtgcgta
     3061 tgaaatgatt tttgagaagt aaagggcttg acggattttt tcaatcaatt cagccttgtc
     3121 tccttcaaag ttgaaggcag ctggttttgg aagcaccttg ctagcatgta cacgttcttc
     3181 tttgtaagtt gaaatgtagc gtgcaaacac tgactcagta atcagtgaca atggtacacc
     3241 aaggtcaaga gatgattggc tcgtccattt accagttccc ttgttacctg cagcatcaag
     3301 gatgtagtct acgattggtc catcttggcc ttcatcgtct ttacggctca agatatcagc
     3361 tgtgatttcg atcaagtagc tgtctaattc acccttgttc cactcagtaa agatttcagc
     3421 catatcctct gcagaaaggc ctagcaagtg ttgcatcaag tcatagcttt ctgcgatcaa
     3481 ttgcatatca ccgtactcaa taccattgtg aaccattttc acatagtgac cagctccatc
     3541 aggaccgatg taagtcacac atggcttgcc atcttctggt gctttagctg agatttcttc
     3601 aagaacatcc gcaaccaatt cgtaggcctc tttttgtcca ccaggcatga tagaaggacc
     3661 ttcaagggca cctttttcac caccagaaac tccagtaccg ataaagttga tacctgagtt
     3721 tgccaattct tcattacgac ggatggtatc tttgtagaaa gtatttccac cgtcaatcaa
     3781 gatatcaccc ttgtcaaggt gtggaagaag ggcttggata gtagcatctg taccaggtcc
     3841 agcttgaacc atcagcatga tacgacgagg tttttcgatt gagtttacaa aactttcaac
     3901 gtcatagctt ggtacaaagt tcttttcagg atggcaagca atcacatctt ccgttttttc
     3961 tttactacgg ttgtagatag caactgtgta accacgtgat tcaatattaa gggcaaggtt
     4021 acgacccatt acggccatac ctacgacacc aaagttagct tttgtcattt gacactcctc
     4081 ttgtttcatt tgttttattt tatcattttt acttttgaaa agaaagaatt ttgtaacgac
     4141 tgcttagtag tccaagtcat ccgcatgacc agcgccattt ccgacaaagt agcctgtctt
     4201 acagttaagg gtaaagagat aggttccatc tggcttatag aggttataat aaccattgcc
     4261 gttaacgata ttgacacgtt caaggatata ttggtctcca gtgatatagc cacgtgaacg
     4321 tgaagtcgct agaatttgtt ccaagacacc atccgcaaaa tcccaggcag agttattact
     4381 atcatcaata gcagactgat tataggcaac acgactggca cttctttgaa cagcaacccc
     4441 tgcactcgag agacccatat tgacttcact gcgactactt ctagtctcat ttgaactact
     4501 tggttttggc tcactagtcg tatttgaact tgcttgactt gaacttgagc tgctagtttg
     4561 acttaaactt gagctagaag tacttgtttg ctggctctta ccaagactga tagccttatc
     4621 tagcacttta tcaagctccg tatttccagt tttaatatct gtaaatttag catccgattt
     4681 ggctttggca ttggtatcca acacaccatc cacaatagct gatttttcaa attgtgcatt
     4741 gacatcttga atagccttga tttgcgttgc tagactatca tatttagatt tggcaagcgt
     4801 atgttcacga ctaccttcca gtttatcaag caaggttttg agttgactca gtttatcaaa
     4861 ctggctattt ttcaaagccg ttttattgct atctgtgtaa aaggcgtcat aaagtgtatt
     4921 aaaatcatcc acatccgatt gattggctgt agttgattga gaagtttcaa tttccttggt
     4981 cgaacgagcc acttgacggt agacataata agcactgaca caaataatta ctgatacaag
     5041 cgccaaaacg gtcaaaataa agcctttttt acttttcttt tctgagtcct cttgatccag
     5101 acgagaaagg ttttgctcct cttccacttc ttcagtcatt tctgttggat tttcatcatc
     5161 tagcaataga ggatccaagc cttgctcctc atcgtccaga ggcaagggta gtaagatgtc
     5221 ttcagaagat ggaacttcct ccgaagaagc ttctgacttc tctacagcct cacgcatctc
     5281 ttgaattaaa tcatccagac tctgagtttc aacgaactcc tcttttttgt attgacgagt
     5341 cgcaaactta tccgcctcaa tttcatctct gtgttgctta acatacttgt ccaaaatgga
     5401 atcctcaggc aagactcctg cttccacttc ttcattttta cgaatagctt gaccaactgt
     5461 tagctctttt gcttcatcaa aatcaaattg cggttcttga ccttcttttt tatgacgatt
     5521 tcgtcttttt ttactcatga gtatcccttt ctattttacc tcttgccgtt tgacacgctg
     5581 accaaaatat tgatatagat ccactttcaa ggttccgttg tataacttac gcttcttatc
     5641 tgcttggcta ccatacttgc tttcaaaagc ttcatcacta gtcaggataa atttgctcca
     5701 agttttcagc ggtgcaaata cttgccccat ctcagcatag agcttggtca cccctgcatc
     5761 atctgacaaa cgttcaccat aaggcggatt ggaaatgatt actccattga ttttatcgga
     5821 acgtaaatcc tgcacgcgca tctgcttaaa agtaatatct cctgcaacac cagctgcctg
     5881 agcattggcc ttagcaattt ccaccatgcg agcatcaata tcacagccca tgatatccaa
     5941 ctcaagctta cgttctactt ttttagccgc ttctgtgcgc acttcttgaa tcaagcgatc
     6001 gctgatccag ttccattcct caaatgcaaa agagcgacga agacctggcg ccatctttct
     6061 agcaatcata actgcctcaa tacagaaagt ccccgaacca caggtcggat caatcaaagg
     6121 cttgtctgga taccagttag aaagttgtaa aatggctgct gccatatttt ccttgatagg
     6181 agcgccacct ttttcggtac gataaccacg tttaaagagg ctagacccgg tcgtatcaat
     6241 catgacagtt gccacatctt tgagaataga gacctcaatc ttaaactctg gaccattctc
     6301 catcagagga accccttctg ggcgagcata gtgtttctgc aatttcttga caacagcttt
     6361 cttagaaata gcctgaacac tgggctcatt gtgaagtttg gacttaacac atttagcttt
     6421 tgaaatcggg aaccgagctc caagtggtaa ataattttcc caatctaaag cgaaaactcc
     6481 ctgaaatagc tcttcaaaag tcttagctgg gaacgttcct acgataattt tgatacgatc
     6541 tgctgcccga agccaaaggt tggtttcgat aatagctctc acgtctcctt gaaaacgaac
     6601 acgtccattt tcaacctgac aatcgtagcc caactctcgc acttcacgac caacgacagc
     6661 ctcaagccct gctgccacag ttgcaattaa attaaattct tttttcatgt tacagtcttg
     6721 caagaccttt ctatatgtcc actttaaaaa atgaggttga gaaaatttct cagccccaac
     6781 ctatatgcaa ttttctataa gccatgtttt gttccagaag tgactaggac cacttccttc
     6841 gataatcatc tgtctaccac taacagctct agctgatagc agtcagaata ctacgttcgt
     6901 ttccgcgtac tccatgcccc gaccaaaatt tgggttgcta gcttgagggg tttaccgcgt
     6961 tccactctct ctgtttccag aaagactccg tcactgtggc actttcaagc ctactctggc
     7021 ttatccaagg acttagccat ttcaactgcc gtaacgattt ctcgtcccta ggcttatggt
     7081 ttcgcctagc acaaacacta caggcatcac agcctgtgct agcatggact ttcctcatga
     7141 gaagcaattc tcctcacgcg attatccaaa aattgcacat ctcaaataac tacttaaaaa
     7201 tctgagttat ctaaaatttg tttaccaaaa acttcttttt ccaatctatt caggcgtttc
     7261 aaaatatcaa aattcgtcat agaacttgta attgccgctt caaggggttc tgcttgaact
     7321 ggtgaaggtt tcggtttacg agttaattct tccttcaaat ccgcaatttc ctgacgaagt
     7381 gacttgacca aggcagcata ggtttcatag tccttgatga catcgtctaa aaactcgtca
     7441 acttctactt tattatagcc acggacttca cgtccaaact cttgttcaaa aatatctttc
     7501 gctgaaaaaa taatacttgc catgtctctc tccattctcg cttgctagta ttattatata
     7561 aaaaaaggca aacaaaaatc aaggtcaaag cttcaatttt cggaaaaatt ttcagcaagt
     7621 tcatttaatt gatcaaatgt taatctcttt ataaaatagt cctcttgatt tttcatcttt
     7681 tggtaaaaat aagctagttt tgtttcattt tcttcatcat aaaaaagata ggaactagtc
     7741 gtgttttcca gcaaaaactg ctggtaatct cttaactgcc ccttgtgttc atagcgagga
     7801 taggcatatt tgacaaagtc tacctgctta aagcgactca gtttcatctg attgccttca
     7861 ttccaatttt ccccatgggt ttcaaaagca aaaatggtgg ccaactggaa accgtattcg
     7921 gttttcatct cctgagcaac ctctaaaacc caatattcaa aacccaaact ccctgtaaac
     7981 acaagccaag acaccccatc tgctgccata gcctctaaat ctttacgtat cgctttttta
     8041 atcaatttaa gacgaggatc cttatcagaa aataaaccca aatcaaaagc agaatagcct
     8101 aaaaccaaag ctgtagccat ttttaaccct ttctgtgcaa attatggtat aataaagtga
     8161 tgttattgta ccaataagga gaattatggt caactatcca cataaagttt caccacaaaa
     8221 aagacaaaca tctctttctc aacccaaaaa tttcgcaaat cgaggaatgt cttttgaaaa
     8281 gatgatcaat gctaccaacg actactattt gtctcagggc ttggctgtta tacataagaa
     8341 accaactcct attcaaatcg tacaagtgga ctatccacaa cgaagtcgtg ccaagattgt
     8401 tgaagcctat tttcgacaag cttcaacgac ggactattct ggcgtttata atggatatta
     8461 catcgacttt gaagtcaagg aaacaaaaca aaaacgtgcg attccgatga aaaattttca
     8521 tccacatcag attcagcata tggaacaagt ccttgcccaa caaggaatct gctttgtcct
     8581 tcttcacttt tcttctcagc aagaaaccta cttattgctg gcattcgatt tgattcgctt
     8641 ctatcatcaa gataagggac aaaaatcaat gccacttgaa tatattcgag aatatggata
     8701 tgaaatcaag gctggtgcct tccctcaaat tccttatctc aatgttatca aagaacattt
     8761 attaggtggt aaaacaagat gaacaaacca acgattctgc gcctaatcaa gtatctgagc
     8821 attagcttct taagcttggt tatcgcagcc attgtcttag gcggaggagt ttttttctac
     8881 tacgttagca aggctcctag cctatccgag agtaaactag ttgcaacaac ttctagtaaa
     8941 atctacgaca ataaaaatca actcattgct gacttgggtt ctgaacgccg cgtcaatgcc
     9001 caagctaatg atattcccac agatttggtt aaggcaatcg tttctatcga agaccatcgc
     9061 ttcttcgacc acagggggat tgataccatc cgtatcctgg gagctttctt gcgcaatctg
     9121 caaagcaatt ccctccaagg tggatcaact ctcactcaac agttgattaa gttgacttac
     9181 ttttcaactt cgacttccga ccagactatt tctcgtaagg ctcaggaagc ttggttagcg
     9241 attcagttag aacaaaaagc aaccaagcaa gaaatcttga cctactatat aaataaggtc
     9301 tacatgtcta atgggaacta tggaatgcag acagcagctc aaaactacta tggtaaagac
     9361 ctcaataatt taagtttacc tcagttagcc ttgctggctg gaatgcctca ggcaccaaac
     9421 caatatgacc cctattcaca tccagaagca gcccaagacc gccgaaactt ggtcttatct
     9481 gaaatgaaaa atcaaggcta catctctgct gaacagtatg agaaagcagt caatacacca
     9541 attactgatg gactacaaag tctcaaatca gcaagtaatt accctgctta catggataat
     9601 tacctcaagg aagtcatcaa tcaagttgaa gaagaaacag gctataacct gctcacaact
     9661 gggatggatg tctacacaaa tgtagaccaa gaagctcaaa aacatctgtg ggatatttac
     9721 aatacagacg aatacgttgc ctatccagac gatgaattgc aagtcgcttc taccattgtt
     9781 gatgtttcta acggtaaagt cattgcccag ctaggagcac gccatcagtc aagtaatgtt
     9841 tccttcggaa ttaaccaagc agtagaaaca aaccgcgact ggggatcaac tatgaaaccg
     9901 atcacagact atgctcctgc cttggagtac ggtgtctacg attcaactgc tactatcgtt
     9961 cacgatgagc cctataacta ccctgggaca aatactcctg tttataactg ggataggggc
    10021 tactttggca acatcacctt gcaatacgcc ctgcaacaat cgcgaaacgt cccagccgtg
    10081 gaaactctaa acaaggtcgg actcaaccgc gccaagactt tcctaaatgg tctaggaatc
    10141 gactacccaa gtattcacta ctcaaatgcc atttcaagta acacaaccga atcagacaaa
    10201 aaatatggag caagtagtga aaagatggct gctgcttacg ctgcctttgc aaatggtgga
    10261 acttactata aaccaatgta tatccataaa gtcgtcttta gtgatgggag tgaaaaagag
    10321 ttctctaatg tcggaactcg tgccatgaag gaaacgacag cctatatgat gaccgacatg
    10381 atgaaaacag tcttgagtta tggaactgga cgaaatgcct atcttgcttg gctccctcag
    10441 gctggtaaaa caggaacctc taactataca gacgaggaaa ttgaaaacca catcaagacc
    10501 tctcaatttg tagcacctga cgaactattt gctggctata cgcgtaaata ttcaatggct
    10561 gtatggacag gctattctaa ccgtctgaca ccacttgtag gcaatggcct tacggtcgct
    10621 gccaaagttt accgctctat gatgacctac ctgtctgaag gaagcaatcc agaggattgg
    10681 aatataccag aggggctcta cagaaatgga gaattcgtat ttaaaaatgg tgctcgttct
    10741 acgtggaact cacctgctcc acaacaaccc ccatcaactg aaagttcaag ctcatcatca
    10801 gatagttcaa cttcacagtc tagctcaacc actccaagca caaataatag tacgactacc
    10861 aatcctaaca ataatacgca acaatcaaat acaacccctg atcaacaaaa tcagaatcct
    10921 caaccagcac aaccataaca tttatcaccc agattttctg ggtgattttg tcatagcact
    10981 attgtattta tgtgcttaac aaaagtctga gaagacatct tctcagactt tttctgtact
    11041 ataaacctca ttggaaaaga tagagactgc ttccgtaatc ttgttaagag gttttactaa
    11101 atactagtct ttcttcgttt ttactacaaa gagagcagat agggctaggc taacacctgc
    11161 taggaagagg gctgtgtcag attgactctc acctgttgct ggcaagattt gttcaggtgt
    11221 ttctggtcta tctatttctt gcttataatc tggcgtctta ccttgatcgg aagctaaaga
    11281 gctaagttta aactcaggtt tctctacagt tggagcatct ggtttcgtag cagaatcttt
    11341 taattggttg agataatctg caaagtattc caccattctt tccgtcaaga gatggttatc
    11401 cgtcgcatat ttcatgcttg cctgaacgct agctacttcc tcttgattgt ctttgtctgt
    11461 taatttctga gccttagcca aagctgcttc atagcctgac aagtcaagag gtgtttctgc
    11521 tacctgtgga cgagtaaaga taagttccgc tgcagattgg tatttatctc caccatctcc
    11581 gtatgtcttg gtaccagtaa ggacaatttt cttagccttg attgtcttac caaagtcaat
    11641 atcttttgac ttattgttat ctggccaatc agttgtagta aaggtatgct ccttgccaga
    11701 ctcatctgtc acaacaagtt tcacatcacg caagttacca tttgaacctg atccacgtgg
    11761 aacataacga agtccagtga tttcagttgg ttctttcaag accatggttg caggcttgcc
    11821 tacatctcct ccgccccatg atgtatgcca taaactagat aagtttccat caaaggcatt
    11881 tgcaagacct tcttgagcct gagcaggagc tgtaagactt gcaaagtcat ctgctaccaa
    11941 agacgttttc ttctgaacca aagcattctt caaggcttca atcttggcaa tctctgcacg
    12001 cgcttcttcc acactgatat catcatcggc ctgactgagg ttaaagaccg cctctttcaa
    12061 agcatccata gactctttgg tgtagttagt catggcaacc gttggcaagt agttcttcag
    12121 agcattttct gtcaacatct tacctgttag ggtaatttct tcgatttgaa gattatccat
    12181 catgaagtcg ttataaccac ggaagttggc atttccacca gaatcaccac gagtattact
    12241 tgcattgcca gttgagtaga tacctaccca agtatcccct gtttctgcac ctgtcacaag
    12301 gaaggttgcc ttcttggctt tcttagaatc tgtccaagta tttggcaatt catgcatttc
    12361 caagttgctt gcttgagtgc cacgacgacc tgactggaat tctcccttac cgactacaaa
    12421 agcatatgta ttgtctgaac ctacttcgta ttcaaaggtt acacggtagg tcttacctgc
    12481 ttcaaaacgg aagttttgcg gaatagtttg gtaaaccaag ttacgacggc tcactagtcc
    12541 atttgtcttg agtgaccaat ttccttcgat aacatcatcg actttcttac cattccaacc
    12601 acgttgtgta tatggatagt gtttttcaga caagtgagtg cggttatctt caacaccttc
    12661 aacaccaccc actacaaatg ggaagatacc ctgagcaaca ttttcaaagt cttgcttgaa
    12721 ggtgccttta cctgtatcat gcttgtctcc atacatgctt gaattgtttt caaaggtacg
    12781 aatttcatca aagtaagttg cttgatcacc agcttcacga ctcaatgtca gagtaacatt
    12841 tgagacgtcc gatcctgttg taaagaaggc gtacatgttt tggaagtaac ttgtatcgtt
    12901 aactgtagca ttgtcacgac gtgtattgtg ggcgtaagcc ttaacatagt tgagcgcgag
    12961 agacttattg gtataagtag tcacttcttt ttcaccagta tttacagtga tgctcgcctt
    13021 ggcattacta cggttatcga caccgacata aacggcatac ttggtatttg gtttcaagcc
    13081 agttaatttc tgagtgagac taactttttc tttgtttcct tgaatacgaa gcatatcgtt
    13141 tgccccttga gacttgacaa tttctgcctt agaagcatcg cctgaaatgg tccaatgttt
    13201 caaggtacca ctgttaaatc cttggtcata gatgtgcatg ccttcactcc atgacatttc
    13261 aggattggtt tgttttgaac gatagagaac gtatggttga tttgctagaa gatctagggt
    13321 aattttacca tcttttacag ttagttcttg ctcttctgtc ttaccttggt cagttagctt
    13381 gtaaaggtaa accttgctct ttgcccaatc gcttggaagg gtccaagttg ttgcaccggc
    13441 ctgcgtattg aagtagtaca tcttttcctt ctcagtagaa agtttcttac catttgcatc
    13501 ccagttccaa ggagtcaagt aagctgaacc atcttggatg acacgtccgt tgagagttac
    13561 tgtacgttcg cgatattgtg ggctattgac atcatttgac ttacgagtta caactacttt
    13621 attattgtca gcatctacca attccactcg catttctgga gtccatttat aggtgctacc
    13681 gttatcggtc atagtcaccg gtgtaccatt ttcccattta cttacagtga agtgttggaa
    13741 atacttggtc atgacatcat gggcaaagag gttagtcacg tagccattgt agtcgctccg
    13801 tccttgccag ccttcaaagt ctttcatgct gtagccacct agcagtggat agttggctgc
    13861 accaccataa cttctgtagt ccccaaccca agcatctttt tggtggttac ggataaagcg
    13921 ggtgatggca ctgttgatac ctttattggt gtagccaccg taggtcaagt cagctgccca
    13981 gtgatggaag gtagagtcgt actcaccacc atggccccac tcgatcgcaa agcgccagcc
    14041 ttgtttgtta atttctttgg caagaacgtg ggtagcccag gcaccgttat cacctgattg
    14101 accattaccc caaacgtcca catagataaa gtcgagaccg tcaccaagtt ttttcttcaa
    14161 atcttcccaa cgtgccaaac gaccatgagc taggtcatag gcagcatcaa tgttgatacc
    14221 ttgatctagc cagttccaac catagctata gcttccatct ggattcttac ggagaatttt
    14281 ttcattgaag tatttagact caggataagt ttctgaagcg ttaacgtgga tacctagatg
    14341 agctccatat ttcttagcct tctcaattag ggtcttgaag tcttcgacac caccgatacg
    14401 cttaccaata tcagcatagt tcaagtgacc agagtcatgg ccttcgctac catatccttt
    14461 aaggagaaca ccttgcccaa gaccatctgt gtggagattg attttcttga taccatccaa
    14521 ggtcataagg aatgggtttt gtgcttgaga accaaagttc atcgcgatac ggtaagctgt
    14581 gatatcctta actttttccc aaccttgagg gttgttcata atgctacgat aagcaatggc
    14641 accatcttgc caatcaactt tcttgtctgc attggcatct tcagtgataa caaccttagc
    14701 acttggaagt tccttcgtgt attctgggaa aacaatgccc ttataagctt tttcccattg
    14761 ccattcagag ctgtggattc ctacatagtt ggcatttccg actgtttctt tataagctgt
    14821 caaacgagtc cagtcattcg aaccaccacc atagctattt tgagagttac tccaaacacc
    14881 agcagcaagc ttatctgtag aaacaaatcc atacatgtaa cccttagcca aatccttcat
    14941 tggattggtt acatcgatat gatcatctcc gctgacatgc gtattgtttg acatggttgc
    15001 cccatcaaac ttagcaccag tttgatcact agaaacagag actaaagcat tgccgaggaa
    15061 actaatagaa gaaagtagtt ttctttcgtc atcaatcttt tgacctggag tgacttgatt
    15121 gtggttgaca atcttggtca catcaaagtg caattgattg tccacaactt gcaagcgtac
    15181 tgtcatttcc gcattgatta agtgagcatc atcgcgaagc ttcatcaagt actctgctgt
    15241 tgtctcattg atttttttat aagtgacttc aggggtgatt cggtggttat tgataaagac
    15301 ttggttgaat tgttgcacct gtcctggcaa agtatgtcca ttcaaggtgt attccttgac
    15361 acgagggaag gcttggtcaa ttactgcctt aagtacctta gactggatcg tatcataagt
    15421 caccttgcta tcgtcaacaa ccggacctgt ttctttctgg gcaggggtat cctctgtttt
    15481 taccctctct tggttatccg ttttaacgct aacaactgtt cgctcatcgt cataagagcc
    15541 cgccttgaga agaatcttct tctcattttt aagatggtca ttgaccgcag ctggtagagt
    15601 cactgtgtca aagagattga catcgttatt gctggcattt agctgaccgt ctgacttgag
    15661 agtgatagag agacggtttg ttgatcctgt ttcaggagca gcaacacgac tacctctata
    15721 ccaagtgcta gttgttggag atttatactc ccagaaccag ccatccttgt cataaccgac
    15781 aaaaacatta ttattggtat ctttaaattt caagaagaca ccaaagcgtg atttgccctt
    15841 ttcagaatct tctttgaagg ttaaatcaac agttgcattt ccattggcat caacggtcaa
    15901 gcccttcttt tcaaacagag ctggtttacc tgcgttatca ttttgagcag ttgaggatag
    15961 ttggttgtag cggacacctt tttcttctcg gatagtgact gttccctgtt gttctttttt
    16021 ctctaccgtt tgccattcag gggttaccgt cttaggcgtt tcaggtttag cagctgcagg
    16081 tttatcctct tttggttttt cttcagccgg tttttctttt tcaagtgcta atagttcttc
    16141 ttctgtctta ggtccatctg taacttctgg agaaccttgg tcttctccca ccttaggcgc
    16201 ttcaaaatca cgcccatcat tctcttttgc tgttgcaaga gcagtagcta aatcagctgg
    16261 taagttcgcc gtggaaccag actgcacgct atctgcaaga accggacttg tcccaaagaa
    16321 tgcagctcca atcataacag aagcaacacc taatgaaaat ttccgaatac tatatttaca
    16381 acgtttttca aataatcctt tattcataaa cttctaaatc ctttcatttt tgagcaagcg
    16441 tttacatttt ctttttaaaa aatactcctt cctctgaaag tgcaatgctt aaccctgata
    16501 aataaaaaat aattatactt ttaatataac aaataataac tgagaaagca ataggaaaca
    16561 agtaaaatta acaaaaattt tctctattct gacaaaaaga gactccaact tttgggggtc
    16621 cgtacattta gaatctttct ttacaaatgt aaaaaaggat tcagcattca agggaaatac
    16681 taaatccttt cttatatttt gcaacagtta tttcacatgt tttgcgagat cttcttgagc
    16741 ctttttatta gactcttctt tttctttcat ccatttttcc tgagcttttt ggtattcatc
    16801 tacagtgact gccttgtctt gaagttccaa gtatttatat aagattggtt cacttgtacc
    16861 tttatttcct gacaatgcaa atggtattgt aaatggtacc atcttagaca agattggacg
    16921 ccctgtacga gatgtagttg gaataatcaa agcactatct gtcaaccaag cttgggctgc
    16981 agcgtattta tcatagcgtt tagcaacatc tgtagcctca tcaccagcct cagtaaccaa
    17041 tttttcgtag tcatatagac ctactttttt agcagctaca ttatcttccc ctgagtcaaa
    17101 ccctaaatat gttttagtac tttctcctac agatggtttg atgatatcaa ggtaggttga
    17161 tggatcggca aagtctggac cccaaccgac attatctgat aaatcccagt cttcgccagc
    17221 agcgttttca gcaaaatatg taatatcgtt tacttcgtct ttttgtagtt gttggatatc
    17281 aataatgaca ttatcagttc ctaaagttgc ttccaaggat tgtttcatag attggacgcg
    17341 ctgaactttt gtagttgctg tctggtcaac tggcatatct aaatgaattg ggaattggac
    17401 tccttctgct tgtaaggcta atttagcttt agcaaattca gccttggctt tttctggatt
    17461 gtaaagacca tcctgagaat ctgcaagatt aacatccttc cattcatccc cataagtgac
    17521 caatttctct ttgaccatat cgccaaagtt tttaccatct gcttgaacaa atgttggtgg
    17581 aacaaagaga ttacgtaaga ttttgcttgc tccagtttgt ccattcaact gagaggcata
    17641 ggctgtacgg tcaaatccaa atgcaatagc ctgacggaaa tccttgttta agagagcctt
    17701 tttcgtagat gttttttgtt cttcactggt cttagatgta tatttatagg actgacggtc
    17761 aatatttgta ccaactagat acgtaataga gtcttgtgat taaatgccta tttccaaatg
    17821 cacaaatcgt ccttgataga tttcatatca tccagcacct aagccgtgag atgatgacaa
    17881 ccagaattgt catcatgaag aattttgaca agcaatcact tccctatcgc gccatgaaaa
    17941 atcactggcg aattttccaa aaagatagcc gaaaactgtc tgataaggcc ttctactcaa
    18001 gaacttttag acagacactg acacctcgag aaatcgtcaa taaaacctta gctttctcag
    18061 atgagctcca ctattatgac gatctttacc agctcctgct tttccacctg caagaaaaga
    18121 atgccgacca tttctttgac ttgttaactg aggcttttcc ccaactcaat caagccttta
    18181 gaactgctct tagcacgctg gttcgctaca gaaaatacgt gacaaatacc atccagatgc
    18241 cctattctaa ctccaagctg gaggcaatca ataaactcat cagccttctt caaacccaaa
    18301 catgtaggta tggttatgtt tttcttcaaa ttcttgaatt ttctcagcga tgaatttgaa
    18361 acctgttaac acgttaaaca tggttgcacc atagctttcc gcaattttgg tgactaattc
    18421 agttgatact attgattttg ccaatgcagc attctttggg agtgtcccag cttgtttgtg
    18481 agcttctaaa atgtatttgg cgataagagc accgatttgg ttaccagaaa ggttccaata
    18541 actgccatca gcttgacgaa tttcaacacc gagacggtca gcatcagggt cagtcgccac
    18601 taatacatca gcatcgactt gacgccctag ttcttcagct aaggcaaagg cggcttgact
    18661 ttcagggttt ggtgatgcaa ctgttgagaa gtctggggct ggttttgctt gagcttcgac
    18721 aacttgaaca gattcgaaac cagcttgtgc taaagctcga cgtgctaaca tttctccagt
    18781 accatgaaga ggtgtgtaga caattttcat atcgcgacca tattggtcaa tcaaatcttg
    18841 attgatatta acgcttttaa cctcttcaag gtaggcagaa tcgagagttt caccaattac
    18901 ttcaataaga ccagttgatt tagcttcttc taagtcagca agggctacag caaatgggtt
    18961 atcaatcgca cgaatatagt cagttaaagc atcagcatca gctggaagca tttgcccacc
    19021 atcagaaccg taaactttat aaccattaaa aggagcaggg ttatgactgg cggttaccat
    19081 aataccagca aatgctccga gatgacgaac agcaaaagac agctcaggag tagggcgtag
    19141 gctttcaaaa acataagatt taatgccatg ggccgctaat acttgggcag attcaaaagc
    19201 gaattctggt gaaaaatgtc gcgagtcata ggcaatagca accccagctt ttttggccgt
    19261 ttcgcctttt gattcaacta atttggcaag gccttctgtt gcttgacgca ccacatagat
    19321 attaatacgg tttgtcccag caccaatata accacgcata ccagctgttc cgaattcaag
    19381 gtttgtgtaa aaggcgtctt cttttgtttt gtcatccatg ctgagcaatt catcttttaa
    19441 ataagctgga agatcaggga catttagcca tttttgataa ctttctatac aattcatagg
    19501 tgtccacttg acgaacagtc atctagcttc tccaattgct taccaagtgc aataacgtaa
    19561 ttttttaaac tctctttaat ctgaggatgt tgaagagcat aatcaattga tgttttcata
    19621 aaattaaact tatcaccaac atcataacgt ttgcccacaa attcacgcgc aaaaacactc
    19681 tgtgtcttat tcaatgtatc aatagcatct gtcaattgaa tttcattacc tgctcctggc
    19741 ttttgggttt ctaatataga aaaaatctca ggagtaagta gataacgtcc aataatagct
    19801 aaattgctag gcgcttcttc tggttttggt ttctctacaa aagcatcaac actatagagg
    19861 ccattactac tttccaatct aggagaaatc acaccataag aagaaacatc ttcatatcta
    19921 acaggcatta ctgcgatagt tgaagcctgt gttgcgttgt aatcatccat caattgtctt
    19981 gttaaaggta cagcagttga gtcggtgata tccataaggt catcaccaag cattacaaca
    20041 aagggatcgt caccaacaaa agacttcgct tggagaacag cgtcaccaag accacgtggt
    20101 gaactttgac gaacgaaatg tactttaata tcagtcgatt cattaactga cttaagaagt
    20161 tccatctttc cttgttttct aagactatat tccaattcaa aagttgaatc aaaataatct
    20221 tcaatagaac gtttactctt tccagtaact actagaatat cttcaatacc cgaacgtaaa
    20281 gcttcttcaa tgacaaaatg aattgtgggg cggtctacaa ttggaagcat ttcttttgcc
    20341 aaagctttag tggcaggcaa aaatcgtgtg cccagccctg cagcaggaat aacagctttt
    20401 tttacttttt tcataacaat tccttacact atttctatta aaataatata agtgattaat
    20461 cttttaacac tcttttcaca ttaaaatatg acccttacgt ctgaagtgag ccactacaga
    20521 tgacaatgag ccttaaaaca aaacttcaac aataatccct aatataatga aaaacaagat
    20581 agctaaaatt gttccagctc gtgtcataat ctgatatttc aagttctttc ttaacattaa
    20641 aaaacacttt tccttttcaa aaatcaatta atactctgag taaatactct atatacgcac
    20701 tactatttat ctcactctgt taaattccta gttccccacc ctaaatcatc agaacatctc
    20761 ataagtccta atagcctaat agggcacata attatactca aaacgattat aaaaacagga
    20821 ataagaaata cataatacca cttcattcta gacatagctt taaagtttct tcctccaaag
    20881 ctaaaaatca ttcccaaaag aacatataaa ataatttccc accatgaagc tgtataaaca
    20941 attgtagtta tatttaatat tttcaacagg aatatattca caccaaagct aataagtagc
    21001 ataggtaaaa tcatatctgt aaaataaata aaaaacataa gaggggcatt tctaatcatc
    21061 caaggagtca tctttagatt gttatactga gaaccttctg cccaccttag ttgctgtcta
    21121 atgaactttt tccaacttgt aggagcatct gtatacacaa cagaagtatc ctgcataaca
    21181 gttttatagc ctttttttaa agtcaaattt gtaagacttc tatcatcaga aacttcctta
    21241 tgaaatccca tgaaagtttc attcataaac tcatgtatac actctctgag aatctctgtt
    21301 ctaaaagcaa ttgttcgacc aggtaagcac cctactttac cagtcacact cattgctttc
    21361 atagttcctt ctgccctaat ttcctctaac aagttagcaa acattgtcac gagattacgc
    21421 tcagggtcaa gaattttttg tcttgtcgtt accccaccta tttttttatc gcaaacaaaa
    21481 ggcttcagca actcactcaa ggttctaggc gtccatactg tatcactatc tactagaact
    21541 gtaatatcac tctgcgaatc cacatgctcc agcccaacgc ggatagcatt tctcttgcca
    21601 ggaacaggag tgtaataaca ttgaattgga gtcatattat tttctaattt ttcattaaaa
    21661 tcatgacaaa gttttacaag tctctcgttt tttgggccgt taataaccac aataatttcg
    21721 gatggtttat gtctggaaat tctattcagt acactttcaa aaagattaag tggttcatcc
    21781 acgacaggga taattacaga actaaataac ttctcatcac ttacactaca actgtaggac
    21841 ttatatctga cagcatgaaa atatataacc gcccaacgaa taagaataaa gacaaaaaac
    21901 aacataaaga aatgaaaatc atgattctga aaaaaatcca ataacattaa aataaatgta
    21961 tacataaaaa ttattgcccc ttattctctg ccaaataaat cgcgtgtata gagtttttct
    22021 tgtatatccc ttaaatcatc gtgcatacga ttcgctacaa caatgtcaga aatattctta
    22081 aattcatcta aagatttaat tactctgtat cccataaaag tatcacactc aatagtaggt
    22141 tcgtaaataa caatttcttt accataattg tccaaacgtt ccataactcc cttaacagca
    22201 ctagaacgaa aattatcaga atcagatttc ataattaatc tataaatacc tacaacacta
    22261 ggttgtttag ctagaatagc tccagctata taatcttttc ttgttttatt agattgcacc
    22321 acagctgtaa tcagattttc aggaacatcc ctaaaacttg ctttcaattg ctttgtgtct
    22381 tttggtaagc aataccctcc gtaaccaaag ctagggttat tatagtatga tccaattcta
    22441 ggatcataac aaacaatatc aataattgtc ttgggattaa gcccttttac ctcgctatat
    22501 gtatctatct cattaaaata agctacgcga gttgccaagt aagtgttact aaacaatttt
    22561 gcaacctctg cttcattaaa agcaacaacc agtatcggaa cctcttcctt aatagctcca
    22621 cctttaagta gatctgcaaa ctgccatgct ctttttgtta actcagaatc atccaaatca
    22681 gttcctacaa caattctaga tggatacaaa ttatcatata aagctttgga ttcacgtaga
    22741 aactctggag aaaaaataat acgatctgta ttaaactttt ccctcacttc tttagtatac
    22801 ccttcaggaa tagtactttt gattacgatt gtacaagtat cattatattc catacaagtc
    22861 ttgatagcag cttcaactga agatgtatca aactgattta agtctacatc ataattagtc
    22921 ggagtagcaa taatagcata ctccacgtct ttataaacgt gtgcaggatc taaggaggct
    22981 tcaagattca actctttttc aactaagtat ttctcaatcg cctcatcctt aattggagat
    23041 tttctattgt ttatcgactc taccttatcc tttataacat caatgacctt aacttcatga
    23101 tgctgagcta gtagcaccgc taaagacagt cctacataac cacttcctgc aatggcaatt
    23161 ttcattttac tacagtcctc tttctctgta ttattaatat tctcacttta tttaaaaagc
    23221 aatagtttaa ttatataata attttatcta ttgtcaaggg gaatatcaaa ctttttttgt
    23281 gccttagtat cagctttgaa aagatatccc gttaaactaa ttactttcct aacctctgtt
    23341 tccaaataat cttccaaatg gacagagata taccgttgtt tgcatcgata gctgaggtct
    23401 tttttagaaa ataccatcac ttttagaaaa tataaacaca tttttcggat aagattaagg
    23461 ttaaaagcag ctcgtttatc cagggtctga tgatggtctt cacgataaac cacatccaat
    23521 aaccaatgca tactttctgc tgaccaatga cctcgaacac tatggcaaaa ggtcatcaca
    23581 tcaagcttaa agttaaagat aaaatagcga acgtcttgac ttgtaatacc atctctatca
    23641 atagtattac gagtcattcc aattccacgc aatttatgcc atttgggatg gttttgacac
    23701 aaccacttaa catcagaaga cacccagtat tctcgaactt caatctatcc tctttctata
    23761 ttctaactga aaggacaatt caatgattca tttaataatg attagcgcca ttgctctagc
    23821 cattggaatt ggttaccgca ccaaaatcaa tattggcctg ctggctattg ctttttctta
    23881 cctcatcgca accactctca tgggattaag tcccaaagaa cttcttcatt tttggccaac
    23941 ctcactcttt tttaccattt ttagcgtctc tctcttttat aacgttgcaa caactaacgg
    24001 tactcttgat gttttggctc aacacattct ctaccgcaca cgcacccacc ctaacgccct
    24061 ctacatgatt ttatacctga tggcaaccct tttgtctgct ttaggtgctg gatttttcac
    24121 tactatggcc gtttgctgtc ctctagcgat taccctctgt caaaaagcgg acaaacaccc
    24181 tttgattgga gctcaagccg tcaattgggg agcttcagga ggggctaatt tgataaccaa
    24241 aggaataaaa tattatgtat tttatcgttt ccaccaactc aatatactga cctcttttga
    24301 aaaaatcttt accataacca caaaattttt actttgtaac aaggctgtag ggtttggtga
    24361 tacagatccc gattgaacta caaataaatt ttcaatattt gtatcacata aaccgtgaga
    24421 taaatcagct atcccagata aaaattctgt tagctctgta attttttcac gagatttaaa
    24481 aaatcctgac ataactgaat ttcgagtatc accatcgatc aaaagagttt tatagcctgc
    24541 acgcgcaaac gaccttgcta tatttacgga agtagttgtt tttccttccc cagggttaac
    24601 agaagtaacg gaaattactt ttagtttatc tccgctcaac tgtatatttg tacacaaggc
    24661 attgtaatat tcttctgcct tcttaatgaa ctccagtttt ttgtgctatt tctaatgtcg
    24721 gcattcctct ctcctatttc aacttaccca agtttggtac aactcccaaa agtgtcatct
    24781 gcagtgtatc ttcgatatct tccggacgtt tcacatgagt gtccaaaagt tcaagaagaa
    24841 gaactataac actagttcca atcccccctg ccaaaaaacc aattagtgta ttgcgtttaa
    24901 tatttggcga agacggtgat atcgccggtc ttgcctcctc cagtgttgcc acatcagaaa
    24961 cacgagtaat actgataatt ttttgagcag ctacttctct caaagagtta gcgatacggc
    25021 ttgcctcttc aggaactcga tcattaactg aaacagagac aatacgggta tcaactggta
    25081 ctgttacttt aattttatta gccaaacctt ttggcgtcaa atctagtttc aaatcagaaa
    25141 taacttcctc caaaacatcc tgcgatagga taatttcacg atagtcttta accaagtatg
    25201 atcctgcctg caagtcttga ttggttaaac cagacttctc tccctgatta cggttaacta
    25261 cataaatccg agtcgtacta gtaaactcag gtttgataac aaaagtactg taggcaaaag
    25321 caactgaaga agttataatt gccactaata aaatgaccaa ctttcttttc cataaagctc
    25381 tgaatagttg caatacatcg atttccaaag tgttttgttc cttcatattt tctcctaaat
    25441 taattgatcc attataattt ttctgggatt atctacaaaa agttctttcg cttttttcgc
    25501 tctatatttc ttagcaatga tatcatatgc ctgttgcata tatggaggtc tactgtctaa
    25561 attgtgcatg tcacttgcaa ctacatgaac taaatcacgt tccaaaaaat accgagctct
    25621 ctttttcatg aatttatatt tttcaccaaa gaacttaggt tttgaaacat gataactatc
    25681 tatctgagta tagcacccca tatcaatcag ttcacgaaca cgtttttcgt tattctctaa
    25741 agcatcataa cgttcaatat gagcaattac tggcgtgatt cccaacatca aaatattgct
    25801 caatctcgta tgaatctcac gataggaagt atgcatgcta aactcaatca aagcataacg
    25861 actatcatta agggtaggaa tttctttttt tctagctttt ctagagcatc cagagtatag
    25921 tatatctctg cgccataagc aatgactaaa tcatctgcta cttcttttgc aatttcacga
    25981 accttaataa aatttgttac aattttttct tctggagttt caaacatccc ttttcgacga
    26041 tgcgaagtag acacaatcat tcgaactcct tgattataag cttctcttaa aagtgccttg
    26101 ctatcctcta ttgacttggg accgtcatct acatcaaaaa cgatatgcga atggatgtct
    26161 atcatttcat ctacctttca tcacatcctg tatagctgct ttaactacag ctaaactact
    26221 atcatctatt tccatcacat agaggttact gtctggcatt gcataagaag gaagatccat
    26281 ccgacctgtc ccttttaaat cttgagaatt tactttataa ttccctccac tttccaactg
    26341 agtattcact aaatctatca tagtctcaat cggcatattt gtttggatag aatcttgcaa
    26401 gctatcaatg atcgtactat aatttttcag ttcttcggtt gacgttaatt tttgaaggat
    26461 agccacaatc accttttgtt gattgcgccc gcggtcacga tcgccatctg ctagggagta
    26521 gcgctcacga acaaaaccga gagcctgttc tgaatcaaga tgaacattgc cttcagggta
    26581 atactttcca ttcgtatggg cagtaaattc ttgatcatta taaacatcaa ttccatccaa
    26641 caaatcaatc aatttcaaaa acgaagtgaa gttcaatcgt acatagtaat tgatatccac
    26701 tccatagaga ttttctaagg tgtgaatgga cgaatcaact ccataaatgc ccgcatgagt
    26761 caatttatct ttttgattat ttccaccatc tgcaattggt acataggcat cacgcggcgt
    26821 tgtggtcaag aggattttct tggtatctcg attgacagtc atcaggatat tgacatctga
    26881 tcgcgacacc gaactaatag gaccataggt gtcaattcca ctaacttaga tattgaaaga
    26941 ctgattctta gacgtcttag gagcttctac ttttttagta aatcccttgg tataaatatt
    27001 ttttatcttc gatgcgtagt ctggatactc tgactcgatg atattttcaa agacactatt
    27061 taggacaatg gtcttggtgt cacctgcaat cagactcttg taagcagcca agtaagacga
    27121 actctggtcg accgtcaaat cggtattctg acttgatatc agctagtaat ttttgaatat
    27181 tttcattatc agtcccagtc ggtgctgtca cactcgtcag ttgcataaca ttttcgatct
    27241 cactatctgc taaaacagcg acactgatcg aatattctga gtaattagaa gtcgcattta
    27301 aacgattggt cagtccaaca aactgctgta ctgcaaagag cgacacagag ctgacaagga
    27361 tagagaacac caacggtaat gtctacacct ttattttcac tatctgtatc tttaagtatc
    27421 ttagtagact tcccgcgaac caaaaatata gtaaaatgaa ataagaacag gacaaatcga
    27481 tcaggacagt caaatcgatt tctaacaatg ttttagaagc agaggtgtac tattctagtt
    27541 tcaatctaat tatgaacaag acccagaaaa agtagcctta tttcttaaga attttaatag
    27601 tttaaagcac ctagcacctg tttagattga cgaaacagga ttcgatactt atttttatcg
    27661 agaatatggt cgctcattaa aaggtcagtt aagaagaggc aaagtatctg gaagaagata
    27721 tcagagaatt tctttggttg caggtctaac aaatgaatgg tgagttaatc gctccaatga
    27781 cttacgaaga gacgatgacg agcaactttt ttgaagcttg gtttcagaag tttctcttac
    27841 caacattaac cacaccatcg gttattatta tggataatgc aagattccat agaatgggga
    27901 agctagaact tttatgcgaa gagtttgggc ataaactttt acctcttcct ccctactcac
    27961 ctgagtacaa tcctattgag aaaacatggg ctcatatcaa aaagcacctc aaaaaggtat
    28021 taccaagttg ttgcaatacc ttttacgagg ctcttttgtc ctgctcttgt ttcaattgac
    28081 tatattatca gcgtaatagt ctaatagata gttaaatgta gttggatttc cactaaaggt
    28141 tgatgagtaa gtttttgtat ctgaacctga ttggccgcaa gcagctaaaa gcaaagcaga
    28201 tgcaaaagtc agacctgcac caaggacacg cttctttatg ttcatcttct ttctccttaa
    28261 tagtgggaat ttgtaaagtt aattgaattt caagaatgaa ggtttataaa ctttggttat
    28321 aaaaaacaaa ggatttctgt cttttataca gtcctccctt gtttttatac gatttcaatt
    28381 ttaaattttt ctgcaaaaaa tatttatagt aattccacac agaaagcatc ccatggaact
    28441 aagatttgtt tttcaaagac ttcttgagct agggtgtttt caatcaagac agatttgact
    28501 tttccttcta ctgtcaagtc ttgctcttca ttggacaagt tagccacaac taggaagcga
    28561 cggtcgccat ccttacgtat ataagcaaag accttatcag ccgtatcaag caattcaaag
    28621 tcagctcgaa ttagccaact attctccttg cgaatttgga ccagtttctg ataggtatag
    28681 aaaatagaat ctggatttgc cagcgcttct tggacgttga tcatctcgta atttggatta
    28741 actgccaacc aaggttgacc tgttgagaaa ccagcgtttt tgctctcgtc ccattgcata
    28801 ggggtacggg cattgtcacg tccaataaca cggatactgt ccatgatttc ttgcatcgga
    28861 acaccttttt caagagcctc acgcgcatag ttgagagatt caatatcttc tacttgatcc
    28921 agtgtttcaa acggatagtt ggtcatccca atctcctcac cttggtagat ataaggagtt
    28981 cctctcataa gatgaagcaa gattgcaaag gctttggcag atttttcgcg gtattcttgg
    29041 tcatttcccc agattgagac aatacgaggg aggtcatggt tgttccagaa gagggaattc
    29101 cagccgtcct caactcctaa ctctgtctgc catttgttga agatttcttt taacttagcg
    29161 atattcagct ctttttgata gtgccattta ggctgacctt cctgatactg aagaccgata
    29221 tgttcaaact ggaagaccat agacaattct tgcccctttg gatcagagta gagtttggca
    29281 atctctggcg ttgctcccca agtctcccct actgtcaaga gatccttatc tccaaaggtc
    29341 gcctgattca tttccttgag atagggatgg agcataggac cattattgac taccttctcg
    29401 tcaggaattt tgccaatcat gtcaataaca tccatacgga aaccaccaat acccttatca
    29461 atccagaagt tcatcatctc ataaattttc tggcgaagtt tttcattttc ccagttgaga
    29521 tccggctgtt tcttgctgaa aaagtggaga tagtattgac ctgacttttc atcgtattcc
    29581 caagcagacc cactaaagat agaatctagg tcattgggtt catcgcgcca gatatagtag
    29641 tctcgctcag ggctattagg attttcacag gcctctacaa accaggcatg ctcatccgag
    29701 gtatgattga ccaccaagtc catgatgata cggatatcac gcttcttagc ttctgcaatc
    29761 agttcatcca tgtcctccat ggttccaaaa atagccgcaa tcgcttgata atcagcaata
    29821 tcgtagccat tatcatccat agggctgtca taaacgggag aaagccaaat cgctgtgatt
    29881 cctagcttag ctagatagtc caacttactg gtaatacctg gcaaatcacc aactccatct
    29941 ccattactat ccataaaact ctttggatag acttgataga ctacggcatt atgccaccat
    30001 ttttcttgca tcttcttacc tcattatttt aataatctat agtatatgat agcacttttt
    30061 aaaattttgt gcaagcgttt gcttaatctt tttaatttct tttttagctc cgtagtttcc
    30121 taacttccaa ttttttatta taatagagtc cagaggtaaa aaatgaaaaa acaagctttt
    30181 agttctgaac aatatttgaa tttacaacgc gaccatattt tggagcgcat taaccaattt
    30241 gacggcaagc tctacttaga gtttggcggt aaaatgttag aagatttcca cgctgctcgt
    30301 gtccttcctg gttatgaacc tgacaacaaa atcaagctct tgcaagaatt gaaagagcag
    30361 gttgaggttg tgattgccat taatgctagc aacattgaac attccaaagc acgtggcgac
    30421 ttaggcattt cttatgacca agaagttctt cgtttgattg acaaattcaa tgaattaggg
    30481 atttttgttg gttccgttgt cattacacaa tacactggtc aacccgctgc agatgccttc
    30541 cgcaaccaac ttgagaaaaa cggaattgat tcttatcttc attatccaat caaaggatat
    30601 ccgacggata tggatcacat catttcccca gaaggcatgg gcaaaaacga ctacatcaaa
    30661 atcagtcgca acttgattgt cgtaaccgct cctggacccg gttctggaaa attggcaacg
    30721 tgtatgtcca atatgtacca cgaccaaatc aatggcatca agtctggcta cgctaaattt
    30781 gaaaccttcc ctgtttggaa tcttcccctt catcatccag ttaacttggc ttatgaagct
    30841 gccacagctg accttgatga tgtcaacatg attgacccct tccatcttca aacctatgga
    30901 gaaaccactg tcaactacaa ccgtgatatc gaaatcttcc cagtgctcaa gcgcatgttg
    30961 gaacgtattc tcggaaaatc accatacgct tcaccgacag atatgggtgt caacatggtt
    31021 ggtttcgcta ttacagatga cgaggctgct gtcgaagctt ctaaacaaga aatcatccgc
    31081 cgttactatc aaacagttct tgacttcaaa gctgaaaaag ttggcgaagc tgccgtcaag
    31141 aaaattgagt tgctcatgaa cgacctcggt atcacacctg cagaccgtaa ggttgctgtc
    31201 gttgcgcgcc aaaaagcaga agaaactggt ggaccagccc tagcctttga attgccaaat
    31261 ggggaaatcg tcactggtaa gaactcagaa ctctttggtc ctacagccgc tgccttgatc
    31321 aacgccatca aaaaatcagc tgacatcgct aaagaagtaa aactaatcga gcctgaagtt
    31381 gttaagccaa tccaaggtct taaaatcgat catctcggta gccgcaatcc acgccttcat
    31441 tcaaatgaaa tcctgattgc acttgctatc acagctacag aaaatcctga tgctgcccgc
    31501 gctatggaag aactcggcaa cctcaaagga agcgaagccc actcaaccat catcttgact
    31561 gatgaagaca agaatgtcct tcgtaaactg ggtatcaacg taacctttga cccatactac
    31621 caatacgacc gcttatatcg taagtaaaga tttcaacctc tccagcctcg gagaggtttt
    31681 ctctctgtct caggagcaac ctttatgata taatgagaga agaaaactga aaggatttac
    31741 catgtcaaaa gaagttattg tcgaaagttt tgaacttgac cacaccattg tcaaagcacc
    31801 ctatgttcgc ttgattgggg aagaaacagg acccaaagga gacatcatct ccaattatga
    31861 tattcgcttg gtgcaaccaa acgaagactc tatccctact gccggccttc acactatcga
    31921 gcacctctta gccaaactca tccgtacccg cattgacggc atgattgact gttcaccatt
    31981 tggttgccgc acaggcttcc acatgattat gtggggacgt cacaccagtg ctaaaatcgc
    32041 agctgttatc aaggattcgc tcaaggaaat cgctgaaact actacttggg aagatgtccc
    32101 agggacaacc atcgaatctt gcggaaacta caaggaccac agcctcttct ctgctaaaga
    32161 atgggcaaaa ctcatcttgg aacaagggat ttcagatgat gcctttgaac gtcatgtgat
    32221 ttaaaatcga gtaggggata atctctagcc cctctcacac caccgtacgt accattcggc
    32281 atacggcggt tcaactaact tttaacgcat gtcgttcaag gtaataatcc aaacacgaaa
    32341 ccagtccgcg tttttcaagg actggttttg atatagcacg tttaagtatc gacttctgag
    32401 ctactatagt atattgaaac tagaatagta cacttctact atacgacatg cccgtcgtac
    32461 ctcaaaagga accagttttt ttcagctggc tccttctttt ttatcctcaa aattctatct
    32521 taggctttct cacgaataac caaaacgcca tcttccatat ctgcttccag atgtttagca
    32581 tctaaatgat ctaagtggaa gtctgtcacc ttatcacgaa tttcttgttc aaccacgcga
    32641 cggagaggac gaacccccat gacttcgtcg taaccttctt ctgtgatata atctttagcc
    32701 acttgactga ctaccaagtc aatgtctttc ttagccaagg tttggttaac ttcagccaac
    32761 atcaaatcta caatcttaga aaggtcttcc ttagtcaagt gtgaaaactc gatgactgca
    32821 ttaaagcggt tgaggaattc tggacggaag aagggtttca aacggtccat caattctggt
    32881 ttatccgcat cttctgtcaa gttggcttca tagccaaatc cagcatttga ggtcgcaata
    32941 atgacagtgt tcttgaagtt tactgtattt ccttgaccat ctgtcaaacg accatcatct
    33001 agaacttgga ggagaagggt aataacttga ggatcagcct tttcaatttc atccaagaga
    33061 atgatagagt atggattgcg acgaacacgt tctgttaagg tattgctatt gtcatcataa
    33121 cccacatagc ctgctgttgt accaattagc ttagaaacag ctgtgcggtc actgtattca
    33181 gacatatcca aacggataat cgcatcctgg gttccaaaca tatcgagtgc caattgctta
    33241 gcaagctccg tcttaccaac cccagtagac cctacaaaga ggaagctgcc gattgggcga
    33301 tttccttcat caaaaccagc acggttacga cggatagcac gagctacagc ttctacggcc
    33361 ttatcttgac caatcacctt gtcttgcaag cgatgagcca tatctttcaa acgttcgata
    33421 tctgaagctc ccatttgcga tactgggata cctgtcattc gttccacaga ttcagccaca
    33481 tcgttgacac ttgcagtcac tttcatatct tctgtgtggt tttcgatttt cctttccaat
    33541 tctgcaatgc gtgttttata gtttagagct gcttcaaaat cttctgcttc aactgctttt
    33601 tcttgcttgt ctttttccgt ttcgatttct cgttcaacag catgcacatc tgttactgga
    33661 tgttgagccg ccaagtgagc agccgttaca tcgacaaggt caatagcctt atctggcaag
    33721 ctacgttgag gaatgtattg aacagaataa tccaccgctg ctttcaagac ttcgtctggc
    33781 aagatgacat tgtggtgttg ttgatagagg tcacgaatgc cttgaagaat tttaaaagta
    33841 ttctctgctg aaggagcatt gaccttcact tcgttgaaac gacgagcaag agcagcattc
    33901 ttcaagatgg tgttacggta ttcgtcttga gttgttgccc caatcactgt caattctcca
    33961 cgagagagag ctggcttgag aatatccgca agccctttag aaccactgtc tccacaagtg
    34021 ctaccagcac caagaatttg gtgaatttca tcaaagaaga ggataatatt ccctgcttct
    34081 ttcacttcat tgactaagtt ttggacattt tcttcaaagc taccacggta ttgagtacca
    34141 gcctcaagac ctgagatatc aatagaaata atttccttgt tcttgatagc agcaggaaca
    34201 tctccgttca caatggcttg cgctagacct tcgacaactg ctgtcttacc aacacctgca
    34261 tctccgacca aaacaggatt gttcttggtg cggcgtgaga ggatttcaga tgtttcttga
    34321 atttccttgt ttcgtccgat aacaggatcc aacttgccct cacgcgcttc tgctgtcaag
    34381 tttcgaccta gttttgcaag gacaccgtct tgtttcatac ctgatgcctg ttgtggcatt
    34441 tgcacatcag tttctgcatt tcctggtaat tgaccagtcg tacgatagtg agcaaattcc
    34501 tcaggtgtga cttcgcgtcc attaattaag taacggcgat tttcagaact gtatcctcgc
    34561 ataccaccca tcaattggtt aaataaatca tccatgttat taaaattatt aaagttgtta
    34621 ttcatattct ttacctcttt ttgtttactt agttatgatt actgatattg actatctttg
    34681 acctttgttt taaaaaattt agactagcta aaccgctact ctacgtacta tttctggttt
    34741 ttctttttca agcaggagta gactatcttt acttctgaag atttctagat gaaacatagg
    34801 ctcacctctt tctattttac tttaaataag tgttctagta aggctttcat ttaccttacg
    34861 ttcataatat actacattag tcagaaaagg tcaatagttt tgactttaac tgaccaatat
    34921 ttttttacac tcttcgaaaa cctcttcaaa ccacatcagc ttctccttat ctacaacctc
    34981 aaaaccgtgt tttgagctga cttcgtcagt tctatcaacc atctcaaaac tgtatagtaa
    35041 aatgaaataa gaacaggata aatcgttcag gacagtcaaa tcgatttcta acaatatttt
    35101 agaagtagag gtgtactatt ttagtttcaa tatactatgt tttgagcagc ctaaagttag
    35161 ctttctagtt tgttctttga ttttcattgt gtatttaaac acaaaaacac cctaaaacat
    35221 cagggtgcca ttcttacatc aaatataaaa ttgctagggt caggagactt gctagaagcc
    35281 caactcccca aaagaagaag tcaaccttcc actcgctcca aggatttcct ttaccagaca
    35341 atcccccaag ctcaaaatgg tgatgtacag gcgtcatacg gaaaatacgt ttaccacctg
    35401 tcagtttgaa ataactgact tgcatcataa cagaagttgt ttcaaaaaca tacacaattc
    35461 cgataatcaa gagagtccat tcttggtgga gagccataga gatagctgcc agcattccac
    35521 ctaaagccaa acttcccaca tcacccataa agatcttagc aggcttatgg ttaaagatga
    35581 agaaactgag caaaccacca atcatggcca gaatcactag aagaatatcc atctgacctt
    35641 gcacataggc aataactcca taggcagaca aactaatcac aacggaaata ctagctaaac
    35701 cgtcaacacc gtctgtcaag tttactgcgt ttgaaaaacc gactagccag aaaagagcga
    35761 agacaatata gaaaatccct agatgcactt gataaccaaa gacagaaagc atatcgccac
    35821 cgcgctcata gaaaagatag aagataactc cacctagaag ctgaagagct aatttttgct
    35881 taggattaag cccctcattg attttacgaa agaccttgag aaagtcatct aaaaatccga
    35941 ccaagccata caagaccaag atgaacaaaa tcattcccac attattgctg aattggctac
    36001 taaatagggc gaaaaagaaa gcaaccaaaa cagaagtaaa caagaaaacc aaacctccca
    36061 ttgtaggagt cccagctttt gcctgatgct gtttgacatc ctcatgcatc tgctggcctg
    36121 taatttgcgc ctttctataa aattggataa aggccggaat tcctactaaa gttagtaaaa
    36181 atgtcacaat tccagcactg atgaaaataa acatattagt ctcctaaagt taatgtaatt
    36241 tttttaatgt ccttgatagc tgtgttagca cgaacatctt gcttctgcac agtagagccc
    36301 gagccttgaa attcaagttc tatattgagc cacttagcaa gggtctcagc agtctccttt
    36361 gtccaaccat acatatctgg aacctcctct gctttatcag ataagataag gacttgctga
    36421 ttcggggcaa gattcttccc ttcttcagca gaactgtttt taatcttcgt tcctgttccc
    36481 acaacgatgg gttgtacaag attgcgacgc aattcttctg ctaaatcacc aggtgaaata
    36541 tccttgacac taggcatagg ataaggactt tgttgactta cttgctccaa agctttagct
    36601 gttgtttgaa gattgagaga gtctttcata gctgaagccc gctccaagat aggattggca
    36661 aattctccca actgaatacc tgaataatgt tcaggttgtt ggaccgtcac atacaagata
    36721 aaatcaggat tttcagccgg actcatcgat acagccgaga aaatatagtc ggttaacccg
    36781 actagataac caccattttt ctcgtcagca atctgagccg taccagactt gagggctaca
    36841 ttttgcccag gaacagttac agttggcttg cctgtgctgt ggttatacat ggttccataa
    36901 accggatccg tccctaccaa aaccatgtta gtccgagtta gactagctgc atctttagaa
    36961 acaggatttc ccacaatttc tttttgagat ttccgagcag tttgatcatt tggatcataa
    37021 atggcactaa taaatttagg ctccagcatg acaccgtcat tagcaatagc tgtaaaggca
    37081 cgaatcattt gtgtctgggt cactgaaatc ccttgtccaa atgagctttg cgcaatgttg
    37141 acaatattat ccgcaggaag ctgaccagca tactcatccg tcaaaccgaa acgggtcgga
    37201 actccaaact taaaacgatt aagataatca agccaggtag catctcccat cttttgctca
    37261 aggagggtca tcccaacgtt acttgagtgt gcaaaacctt gagaaaaagt catcattctg
    37321 ccaccagtca atccttcatt aacgtcccaa tctcgaatcg tggcatctgc aatttttaac
    37381 tcactactat taaagacttc tcctcctgga aaggtattat tatcaatagc agcagccaac
    37441 atcatcactt tcatagtgga acctggctca tagttacttt ggtaaaggat atcacgccaa
    37501 acaaagtcct ctgtaatgcc ttcttttgta tctgcatcaa aggtcggtcg ttgcgttgtt
    37561 gccagaattt cccctgtttt agcactgacc aaagtcgctg tcatgtactt tccttttacc
    37621 ttctcttgaa aagcatccat ctgggtttcc ataaaggact ggagggggct ggaaatggtt
    37681 gtataaacat ccttaccatc catcgttcgt tgggaaactt gttctgttcc gggtacaata
    37741 ttacccagac gatccttttc ataggtaata atgccgtctg tccctgcaag aatactgttc
    37801 aaggaactct ccattccaga ggttcccagc aagctcttgc ttccatcttc attttcatgg
    37861 agctgagcta gaccgataaa actagaagca aattgtccat ttgggtaact acgattggga
    37921 ctggttgtaa aatcaatccc cttgacctct gcagcttcca attctttttt gatagacatc
    37981 atattggcat aggtaatccc atttcccttt gctccaaagg aaacttgctt gagattaggt
    38041 tgcgagagtt gctctcttac ataggattct tccatgtcca gatacttatg aaagacctct
    38101 gcaaccttgt taaattgtgt tttttctacg taaagaatct tacccgttgc tgacttatag
    38161 ttctcatcaa tgaccgcata gacattatag gaggttgcat cctcagcaat cgggactcca
    38221 tttcggtcat aaatagtccc acgtttggca ggaactgtac gggtggtttg atgaaccttc
    38281 ttagcttcct tcgctaaatc tgttccaaag cgagtgcctg tcccaataat gaccgcaaaa
    38341 ttgactaaaa aaatggcaaa aacaaagaca gataataaac tcagactttt tccaactctg
    38401 cgtctgtttt cagccggcga tttccgattt ttggtcgcat aacggattac tctttttgtc
    38461 cacttcatat cttactccgc tattctaata ttttcattgt ttaattgcaa atcgtgtgaa
    38521 ttggcaattt ctttcaaacg ttctgcacgt aatagttcat tgacctcttg cttggcatcg
    38581 tccaattcgg ttttcttttc ctctatctgc gcattgattt ttgtcaaatc attctgcact
    38641 tgcaagagct tggtctgcat aaaaataata ctaatggcta caataagagt ggttacagca
    38701 atggaaaagt aaaaagcttt ttccacacgc gaaaaccgtt taagttgcat ctgtagtatt
    38761 tgacctgttt tttccatttt ttctgccatc tttttccctc ttacttgtga atttttctgg
    38821 ccacgcgcaa cttggctgag tgcgagcggt tattggcttc taactcttcc gcacttggca
    38881 agattggctt acgggacacc aattccatct tgggcttgag atcatctggg atgaaaggca
    38941 agccttttgg aacttcaact gttgaagctt ccttgaacaa ttgcttggtc aagcggtctt
    39001 ctaaggaatg aaaggtaatc actgaaattc taccatccag agccaacata tccatagcct
    39061 gctggatgga ctcatctgcc gctcccagtt catcattgac ttcaattcga atagcctgga
    39121 aaatctgctt agcaggatga cccttcttct tgagttcctt ggcaggtttg accaacttga
    39181 taatctctgc taactcagtc gttgtctcaa tcggcttcac ttcacgcgct tgctcaatct
    39241 tacgcgcaat ctgtttagag aatttatcct caccgtattt gaagaaaata cgaaccaaat
    39301 catgatagtc ataatgatta accacttcat aggctgtcag actagcatcc tgattcatcc
    39361 gcatgtccag tggcgcatcc tttttataag aaaaaccacg ctcacgctgg tccaattgag
    39421 gactagacac tcccaagtca taacaaattc catcaatttc ctgaacacca gcttcgcgca
    39481 aacgtgcctg taaatgacgg aagttatcct tgataaaggt caccattccc ttctcaatgt
    39541 aaggtgccaa gcgtttttgc gcattgtcaa tggcattctg atcctggtca aaggcataga
    39601 gatggccttt ttcacttaat ttacttaata aatactcgct atggcctgct ccacccaaag
    39661 tcgcatcaac gtagataccg tcaggtttta cgtcaagcat atcaatcgtt tcgtggagta
    39721 agaccgttac atgatgaaat tcttttgtca tatcttatct attttaccac aaatccgacc
    39781 agcttgcact tgtcagacaa ataggacaag gagactacta tttcttcaaa aaatatgtca
    39841 aaaatacttg acactttatg tttaaaagac tataatatag tcaaatatat acgacataaa
    39901 tcagaaagga gaccagatga atcgtgtgaa agaatttcgc aaggaattgg gtatttccca
    39961 gctcgaactc gccaaggata tcggtgtctc gagacagact atcaatatga ttgaaaacga
    40021 caagtacaat ccaaccttgg aactctgtct caatctcgcc cgcagcctcc aaactgacct
    40081 caacagtctc ttttgggagg aagattttta aaaaaggagc aaactcatga aaaaagaaac
    40141 cttcactgaa aaactgatca aacgcacata cggtatttct ggtccccttg acgaatacaa
    40201 acggcgtgag gccgatagta ttgggaacca agtctttatc gtcctctttt atctgatgat
    40261 tttcggaaat cttattccac tccttctggc ctataaatac cctcaagaag tggctctaat
    40321 ctatcctcct ctgattttag taattgccct catcgctgct ggctatgtca cctaccaaat
    40381 gaaaaaaaca ggcatcacag tcattgaacc agatatgctg aatgagaaag aaagcaagca
    40441 actacactac ccaggtctta aagcaggttt gttctttggt ctatggatgt tttttataac
    40501 tcctcttctc agtatactca tagatgaagg tcaggactat tttcattctc ttctcactat
    40561 aagaaatggt gtatcaagta ttctcggttc tattttcttc ggagcgagca tacagttcct
    40621 catctcccgt cgcattgcaa aaactaagaa aaatcaagat gaggattagg aggaaactca
    40681 tgaaaaaaga aaagaaacag ttacgttatc ctggtctgaa agcaggttcg atttatggaa
    40741 cagtgatatt ttttataatt ccactcattg ataccctaac aagtgaaaat ccaaatttta
    40801 tcagttctct tctaaataca aaacatattt ttaaaactat actgggagct ttctttttcg
    40861 gagtgatgat acatattgtc gactcacttc gtattgcaag agctaaaaaa gaccaggatt
    40921 aggaggtgcc ttatgaaatc actagctaga ctactgaaca ttcatgtttt tatcagtatt
    40981 ttccttttct tcgcccttat ttcaggagct gtttctcata cagttttact actcctactc
    41041 ctctttcttc ctgcgctcaa taaaggactt gagaaaatac aatcaaaacg gatacctgtc
    41101 ctcaacgcag ccctcttctt tctcctcata tcctttccac aacttttaac caaccctgtc
    41161 caatggaaat tttcaatatt cctagtcgta accatcattt caagtttggc ctacttctat
    41221 aacttttatc aagtagttaa agaagtagat caaaaacagt tgatttagga gcttgctccc
    41281 ataatttctc atttcatagg caaataatcc cacctagaac aagctaggtg ggattatttt
    41341 atttcttaac agagattgca agtcattttc cttcatttta gaaagtcgac tctttccaat
    41401 tcacactaca atccaagact tgttgccttt cttcttgatt gcggccttca atctggtcaa
    41461 tcaaaatctt tgtagcctgt tgtccttcct caaaggaggg ctgaaccagc gtcgaaacac
    41521 ttggagaaga aaagcaagtc cactccgtat tgtcaaaacc aatcaaccca acttgcggca
    41581 agttataatt caactctttg ataacggtaa agactagagg tagggcccaa cagttaggga
    41641 taaataccag agttttttca tcgggatcga tttctttttg taaaaattct ttaatttgtt
    41701 ccaaattcgt atgcttatct tcaatggtta gactggcgtg acgcatatta gcatctgtta
    41761 aagcatccac aaaaccactt gcccgctcaa tccgagtact caaacgactc gtatccgctg
    41821 taatcaagag aaaatgctca taaccttttt cgatacagga ctgggtcatg tcataaacgg
    41881 catcatagtt attggtttta acccagctag tccggtgttc atagagctga ctatcaaaaa
    41941 agaccatttt cttctttttc tcatcgataa tacgagaata ttttcggaaa ttagaggtcg
    42001 gctgaataat aaagccgtct actcccaaga gaagcatgct ttcaatatac cggtcctcac
    42061 tctcttggct gtaattacta tttcctatca ttacctggta gccattctgg ctggcgatat
    42121 cctcaattcc cttaacaatt tggtttgaga aactgttggt aatatcaccg atcaaaacac
    42181 cgattaattt tgttcgtttg gagtttaagc tacgcgcaac aatgctcggt ttgtaatttg
    42241 tttcatgaat aactttttca atcttttcac gtgtctcttg ggacattttt tcatatttcc
    42301 cgtttaggta aaatgacacg gttgttttcg aggtctgagc catttccgca atgtctttta
    42361 tggtcagttt cttctccaat ctaaaacacc tcctactaat acttattata acatattcac
    42421 tattcaaaat gcctatttct agcactgcaa gcgaatcatt ctctcattta ttttatcata
    42481 tactagacat tttccacgca tttttgttcc gtcaacgagg cacaattttt cacctacacc
    42541 aatatcctcg cttaataaca gaatcagctt gtctgtttcg tcatttttca cttcaaaagc
    42601 cagagcattt tccacttcac gatcatctgt ctggtagaca gaatgacgga tgatttcaaa
    42661 actctcatgc gcaatgatgg tataatccag catctgattc tcaaagaatt ggcgcttggt
    42721 gagtttgcta cttctttcaa gctcattgta tttaggagaa atgatggtat cttccaaatc
    42781 aaaatcaact tcactccata gtctcaactg attgattttc ccatcttgat aggtcacatc
    42841 cttgtcaagg ataaactgag tcaacgcctc atgctgacct tgacacctga tgtcatctac
    42901 caagagccag acatcctcta ccaacatgag gatttttctc ttgtgaagat aaggcaaatc
    42961 aggttctgct gaccaataag ccccttcaat ataatgcatt ccctcccttt ctttatggtg
    43021 acaaaacagg gagtgaggat agtattcata ttcccaggat cccgtgattc tttccggagc
    43081 tttcccatct acaatgcagg tcgaatgact ccaagcactc tttaagagat aacgttcata
    43141 tatctcccga taagaataac gcccagcatc tatgaaaata ggttggcctt gatactgtaa
    43201 gcaaaaacta ttctcgtcac tatggctatg ggcacttcct agcggaccat ttttgaaaaa
    43261 tagataacga tgttcatcct taatgcagac atgtccagag tcttcaaaga tcatggactt
    43321 aggctgccaa gctctctttt caaattcctg cagtcgcttg accttttctc gccccaggaa
    43381 caagaggcta agcaaatcga ctttaacatc cagaccgtta agaaggtctt ccttgttcaa
    43441 aaccacagca gacaggctca aaatttctgt cgtttctgta gaatcgctat caccaaaagc
    43501 caaagttcgt ccatctaagc ctgtcatcat ttgaatatag gtcgccatct tttccagcaa
    43561 ctcttggtaa ctatcttgca agtctggaag caagagacac aaatccagca aggctttata
    43621 aacctctaca tgatagagaa tcgactgttc aaactggctt ccatctccta aaatctgtgt
    43681 ctcaatttgc tgtttcaact cctctgaagc aaaatggtaa gcttcttcta ggtccatctt
    43741 atctgcaaag aaatgataga tagcaagcat cggaattgtt tgtaaaatcc cccagttact
    43801 aagggtgtac ttggcgcgat agtagctttt cataaagtca atctgctttt ctagactgac
    43861 caaaattttc tctagttctt tctcctctag caagtcaaat ttcaagagga gcaagagtag
    43921 tttcaaccaa gtaaaggaac gaatacccgt atccaaggtt ctagtcatca aggattgagg
    43981 agaaaattct ctcacctgct caatccaatc aaatagaaag aacttgcact tttgaatata
    44041 gtccttatct ccttctacca cataccctat cataaactgc aagagatatt cttgtcgatt
    44101 gagcatataa gcccattctg gatcatcttc aaatacttga tcccatacca tcggctggat
    44161 ttgatggatt tttgaacaag gctccatatc ccaaggacta tcaaacataa aacgattgtc
    44221 catcaagcgt tcaagggaac tcttgacttt ctcatagtct tttgaacagt gggacaagat
    44281 ataatcacga cattggtttc catcgattct ttcaaaaaat tgtcttcttt cttctttcat
    44341 tatctattac cagaaaaaga actacttaaa aagcagttct tttgtctttc ccattacact
    44401 ttccttttct acatagatga ccacaccttt tgcaatctgc aaggagacca agtcatcttt
    44461 gatagaaatg atttttccat gaattccaga caataacaac acttcatcac cagatgttaa
    44521 agaagctaaa tactcttgtc gttgctccat ctgtttgcga agcaactttt gctgacgaat
    44581 agaatgaaag cttgacagta aaaggggact cactgccaag acaatcacta ttccataaaa
    44641 caatgttgta tccattaagc tataatctta agccagcttc cgataattcc gatgataact
    44701 gttaaaataa cgagtttata tgttgtccat ttcttttctt tgatcaagta gtaaactaaa
    44761 agtgtaaata gggctggtag aagagctgga gcaaccttat caagcattcc ctgaatactt
    44821 acgatacttt gtttagcgtc tgctttaact tcccctgcag caaaggtaat cggcaccata
    44881 atcttaacag atgtcgctgc caaaccagca attacggtta caccgataat attggcaata
    44941 cgagaaatcg ttgccatctg ttcgcttagt ttatcaatca cagttgttcc tagtttgtat
    45001 ccatacaaac cagttgacaa tttaatcgct gttaaaatcg tattcatcgc aaggaagaac
    45061 aagattgggc cgacaaccaa gccttcttga gcaaacgaag ctgcgatggt tgagaacaat
    45121 ggagctaaac agaattgaga aagagaatcc ccaatacctg ccaatggtcc catcaaggcc
    45181 atcttgatac tacgtgtttc ttttgccgga cggccatttt ccaacattac aagatgcaag
    45241 ctggtaataa aaggcaggaa gtgtgggttg gtattataga attcacagtt ttcttccaag
    45301 gcttggtaga aaccttcctg atcctctcca tagtgttttt tcaaagcagg atacatcaca
    45361 ttggcatatc ccaacccttg atagttacta tagttaaatc cattttgaca aaagaatgcc
    45421 cgcaaagacg ttttaagata atcacgtttt gttaatttgt tagatccagt catcgtgtgc
    45481 ttcctcctct accacatgat ccgctgtttt tggcttgtta taaaattcaa tcaaagcaaa
    45541 gatagtacct acaattgcaa taccaattgt tgggatgttt agataagctg cacaaacata
    45601 tcccaacaag acaaagggaa tcaactcttt cttagccatc actgacaaga tcatcgcaaa
    45661 accgatagct gggagcattt taccagcaac tgtcaaacct gtaagcaata ccggtggaat
    45721 gtagtctacg agtttcaaca aggtatccat tgaaagggca cccaagcaac ccaaggtaaa
    45781 tccaataaag gcaaacaacc aaattgttgc atttagagtg aacttaaatt tcttcaaatt
    45841 atggtttttc aagtgcttca tcgctgtttc aggcgcacca gcacgtacag tgtaggcgaa
    45901 agtttgtaag aattgaatcg ccacagcaat cggagtagag agggcaagag ccgcttctgg
    45961 actgacttta ccagcactag tgatagccat caaggtacca aagataccag gtccgattgg
    46021 gtttggtgga acagtacctc cagcaccaac accgaatccc atataagcca attcaccaat
    46081 agctcccatt gcaagagcag taggcagatc acctagaata attccgacac caaatgacag
    46141 aacaatacat ctattggtgt aaattcctaa cagcattcca ctaaaacaga aagctgtcca
    46201 taatccaatt aaaatcgctt gaaatacatt aatcgacata acgatctcct cttttaaata
    46261 tagtccataa tgttgacttg aacagctcca tcatttcctg ttggagttgt tttcgtatta
    46321 aatgttactt gatgagtttg gctcaattcc ttgagggcca ccttgtcctc ttcacccagg
    46381 aagatggagc gtgtcacttg ctctttacca gtagcattgt gaatgttccc aatattgatt
    46441 tctttgatag ggacaccacc ttctaccaag gttaaagcat ccttcacatc ctttacaacg
    46501 ataaagatcg tttgagcagg attagccttg tgaatgatat caatcacctt ttgcaaaggg
    46561 aagaaacgca tggcaactga gtctggcaca actgttttca tcagagtttg ttgcatcttg
    46621 tccgtgctta cttcgtcatt ggcaacaatg accgtattac aacctaggta ttttacccaa
    46681 agttgtcctt gtccatgaat caaccgttca tcgatacggg tcataataat atttggcatt
    46741 gtcatatttc tcctctacca atataggttc cagtctttgt agaaacggat aagggcttct
    46801 aggtaatagt agtcacccca gatattgcct tcatccactc ctttacctga atgccatgag
    46861 tacacaccgt ggaggagact tgtcccacca ggggtaaatt gatcatttgc ataatgttcg
    46921 atcaaggaac gaagcatggc atgcatagca tgtttataaa tatctttgtc agcatccacc
    46981 tctgggagat gttttagcat ttcatgaatc ccacagacgg cgatagctgt tgctgaagaa
    47041 tctcgtgatt gatcactacc atcattaaaa atcaaatccc aataggacac atgatctttt
    47101 ggcagacgat tcaagaaata attggtcata cccttaaaca agtcaaagca ggactcgtct
    47161 tttaagtgac gataagtcaa aggaatacca tagactcccc atgactgacc acgtgcccag
    47221 catgaatcat cactataccc ttgtctcgtt acacctttaa agggttgacc tgtctcagga
    47281 tcaaaataga aggtgtggaa ggacgaagcg tcatcacgga ttacattatt agctgaagca
    47341 tagaaatggc tttctgcaat atcgtagtat ttttgatcgc ctgtttcttg ataagcaaag
    47401 aataagagtt ggatattgag caagcaatcg ataatcaaac ggtaatgctc tttcttgccc
    47461 aagtctcccc aagcttgaat aaaaccacct ttttcttgat agcgttcaat caacttatct
    47521 gcagctttca aggctgcttc tctagcctct ccatcttcat ttatcttata ttcagccata
    47581 caagacggtg tgtacaagaa gccgagatca tggtgagcca attctactct cttattgaca
    47641 cgatccagga aagaaagaac atttttatga gcgatgtttt taaatgcatc ctgttgactg
    47701 tattcataag ccaaccacag ttctcctgtc cagaaaccat tggtccattc cgtgttatcc
    47761 atgattggat agacattatc aaaggtagct ggtgtcggga aatcttcctt gaaatagtca
    47821 aggttgagtt ctaactgccg aataacctta tcgattgcct ggccgacttc ttctttcgtc
    47881 agaagtggta cttctaagaa gcgctcaggc gattttattt tttcaatcgt aacctttttt
    47941 atcattcttt taccctttaa atacccgatt cgaaatcttc ttcctcttcc tctgcatccg
    48001 ttgaaaacaa ttctttacca tttacgactc cgccctgggc cgccactact gatttattaa
    48061 caacttcatc aaagctatga gccattctag caaagactgc ttccattaac atggctaagt
    48121 tcaaacccga gagaacattc attgttttgg ctggattttc tcccattatg gtagaagaaa
    48181 ccttgaatgg cgatcctccc aagagatcac ttaggattaa aacttcttct tcatttgaaa
    48241 ttgcaagtaa gattttttgc ttgagttcat ctgctgacat tccttccaca aagtcaatcg
    48301 cctccacatt ttcttgattg cctgcaatca attgtaaaga actataaatc cctgtagcaa
    48361 aatgtccatg ccctacaagt acaattttca tcttttctcc tttcttgttt aggtttaccg
    48421 gtttacttta tattccccat tgtaatcctt
//
LOCUS       DAVKMO010000010        46806 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVKMO010000010 DAVKMO010000000
VERSION     DAVKMO010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.010"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(110..1777)
                     /locus_tag="VW361_000653"
     CDS             complement(110..1777)
                     /locus_tag="VW361_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU9743749.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(1780..2145)
                     /locus_tag="VW361_000654"
     CDS             complement(1780..2145)
                     /locus_tag="VW361_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9743750.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(2302..2490)
                     /locus_tag="VW361_000655"
     CDS             complement(2302..2490)
                     /locus_tag="VW361_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU9743751.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(2606..3091)
                     /locus_tag="VW361_000656"
     CDS             complement(2606..3091)
                     /locus_tag="VW361_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HEU9743752.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNVQIDSSILKGYRLPFEGLSYAAFFRYFIPKYVSESRVL
                     YLDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLINNGMWRAENVTQDL
                     I"
     gene            complement(3519..5063)
                     /locus_tag="VW361_000657"
     CDS             complement(3519..5063)
                     /locus_tag="VW361_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU9743753.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLELLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMTPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            5276..5578
                     /gene="gatC"
                     /locus_tag="VW361_000658"
     CDS             5276..5578
                     /gene="gatC"
                     /locus_tag="VW361_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU9743754.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGIDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            5578..7044
                     /gene="gatA"
                     /locus_tag="VW361_000659"
     CDS             5578..7044
                     /gene="gatA"
                     /locus_tag="VW361_000659"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU9743755.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMNEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            7044..8486
                     /gene="gatB"
                     /locus_tag="VW361_000660"
     CDS             7044..8486
                     /gene="gatB"
                     /locus_tag="VW361_000660"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU9743756.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            8615..9175
                     /gene="efp"
                     /locus_tag="VW361_000661"
     CDS             8615..9175
                     /gene="efp"
                     /locus_tag="VW361_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU9743757.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            9197..9586
                     /locus_tag="VW361_000662"
     CDS             9197..9586
                     /locus_tag="VW361_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9743758.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            9579..10001
                     /gene="nusB"
                     /locus_tag="VW361_000663"
     CDS             9579..10001
                     /gene="nusB"
                     /locus_tag="VW361_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU9743759.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(10050..10658)
                     /locus_tag="VW361_000664"
                     /pseudo
     CDS             complement(10050..10658)
                     /locus_tag="VW361_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520572.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(10676..10861)
                     /gene="briC"
                     /locus_tag="VW361_000665"
     CDS             complement(10676..10861)
                     /gene="briC"
                     /locus_tag="VW361_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU9743760.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(11020..11787)
                     /locus_tag="VW361_000666"
     CDS             complement(11020..11787)
                     /locus_tag="VW361_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU9743761.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(11784..12650)
                     /locus_tag="VW361_000667"
     CDS             complement(11784..12650)
                     /locus_tag="VW361_000667"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU9743762.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(12687..14054)
                     /gene="accC"
                     /locus_tag="VW361_000668"
     CDS             complement(12687..14054)
                     /gene="accC"
                     /locus_tag="VW361_000668"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU9743763.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(14066..14488)
                     /gene="fabZ"
                     /locus_tag="VW361_000669"
     CDS             complement(14066..14488)
                     /gene="fabZ"
                     /locus_tag="VW361_000669"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU9743764.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(14485..14970)
                     /locus_tag="VW361_000670"
     CDS             complement(14485..14970)
                     /locus_tag="VW361_000670"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU9743765.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(14973..16208)
                     /gene="fabF"
                     /locus_tag="VW361_000671"
     CDS             complement(14973..16208)
                     /gene="fabF"
                     /locus_tag="VW361_000671"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU9743766.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(16230..16961)
                     /gene="fabG"
                     /locus_tag="VW361_000672"
     CDS             complement(16230..16961)
                     /gene="fabG"
                     /locus_tag="VW361_000672"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU9743767.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(16995..17915)
                     /gene="fabD"
                     /locus_tag="VW361_000673"
     CDS             complement(16995..17915)
                     /gene="fabD"
                     /locus_tag="VW361_000673"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU9743768.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(17908..18882)
                     /gene="fabK"
                     /locus_tag="VW361_000674"
     CDS             complement(17908..18882)
                     /gene="fabK"
                     /locus_tag="VW361_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU9743769.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(19001..19225)
                     /locus_tag="VW361_000675"
     CDS             complement(19001..19225)
                     /locus_tag="VW361_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9743770.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(19284..20258)
                     /locus_tag="VW361_000676"
     CDS             complement(19284..20258)
                     /locus_tag="VW361_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU9743771.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(20258..20692)
                     /locus_tag="VW361_000677"
     CDS             complement(20258..20692)
                     /locus_tag="VW361_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9743772.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(20786..21571)
                     /locus_tag="VW361_000678"
     CDS             complement(20786..21571)
                     /locus_tag="VW361_000678"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU9743773.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            21896..23260
                     /locus_tag="VW361_000679"
     CDS             21896..23260
                     /locus_tag="VW361_000679"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU9743774.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRELTPIKEEEILRQLVQKTKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGK
                     SKED"
     gene            23263..23634
                     /locus_tag="VW361_000680"
     CDS             23263..23634
                     /locus_tag="VW361_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU9743775.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            23848..25122
                     /gene="serS"
                     /locus_tag="VW361_000681"
     CDS             23848..25122
                     /gene="serS"
                     /locus_tag="VW361_000681"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU9743776.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(25147..26046)
                     /locus_tag="VW361_000682"
     CDS             complement(25147..26046)
                     /locus_tag="VW361_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU9743777.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(26156..26704)
                     /locus_tag="VW361_000683"
     CDS             complement(26156..26704)
                     /locus_tag="VW361_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU9743778.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(26922..28244)
                     /locus_tag="VW361_000684"
     CDS             complement(26922..28244)
                     /locus_tag="VW361_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU9743779.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFTALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSQVVIAETKKYFDK"
     regulatory      complement(28335..28423)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(28587..30923)
                     /locus_tag="VW361_000685"
     CDS             complement(28587..30923)
                     /locus_tag="VW361_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU9743780.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLTSREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRVLKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(31027..31575)
                     /locus_tag="VW361_000686"
     CDS             complement(31027..31575)
                     /locus_tag="VW361_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU9743781.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(31572..31874)
                     /gene="zapA"
                     /locus_tag="VW361_000687"
     CDS             complement(31572..31874)
                     /gene="zapA"
                     /locus_tag="VW361_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU9743782.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            31961..32842
                     /locus_tag="VW361_000688"
     CDS             31961..32842
                     /locus_tag="VW361_000688"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU9743783.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            32846..33460
                     /gene="lepB"
                     /locus_tag="VW361_000689"
     CDS             32846..33460
                     /gene="lepB"
                     /locus_tag="VW361_000689"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU9743784.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            33587..35953
                     /locus_tag="VW361_000690"
     CDS             33587..35953
                     /locus_tag="VW361_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU9743785.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMILAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQTCMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(36001..37284)
                     /locus_tag="VW361_000691"
     CDS             complement(36001..37284)
                     /locus_tag="VW361_000691"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU9743786.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQSLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(37478..37837)
                     /locus_tag="VW361_000692"
     CDS             complement(37478..37837)
                     /locus_tag="VW361_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9743787.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPIIAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(38136..39050)
                     /locus_tag="VW361_000693"
     CDS             complement(38136..39050)
                     /locus_tag="VW361_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU9743788.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LQDSPGTNNFSLPNVSPTYGQYYTNQSEVIIGKNDLVKVKNTLQYPYSTSAYVESEFR
                     GVKNGKDVTYRGSANFIKDNVLITAAHNIYKHEFGKDAEELYVTPARTPNSVPFGRIK
                     VKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLTGITVTITGY
                     PSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASNRVVGVHTLGDGAN
                     QINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(39200..39466)
                     /locus_tag="VW361_000694"
                     /pseudo
     CDS             complement(39200..39466)
                     /locus_tag="VW361_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(39491..39802)
                     /locus_tag="VW361_000695"
     CDS             complement(39491..39802)
                     /locus_tag="VW361_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU9743789.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(39727..39969)
                     /locus_tag="VW361_000696"
     CDS             complement(39727..39969)
                     /locus_tag="VW361_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU9743790.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(39970..40602)
                     /locus_tag="VW361_000697"
     CDS             complement(39970..40602)
                     /locus_tag="VW361_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9743791.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQATVYAFQHHLVGQEEF"
     gene            complement(40616..41611)
                     /locus_tag="VW361_000698"
     CDS             complement(40616..41611)
                     /locus_tag="VW361_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9743792.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(41608..42306)
                     /locus_tag="VW361_000699"
     CDS             complement(41608..42306)
                     /locus_tag="VW361_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU9743793.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(42384..43394)
                     /locus_tag="VW361_000700"
     CDS             complement(42384..43394)
                     /locus_tag="VW361_000700"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU9743794.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYIKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(43378..44385)
                     /locus_tag="VW361_000701"
     CDS             complement(43378..44385)
                     /locus_tag="VW361_000701"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU9743795.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKAAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(44372..45325)
                     /gene="mvaD"
                     /locus_tag="VW361_000702"
     CDS             complement(44372..45325)
                     /gene="mvaD"
                     /locus_tag="VW361_000702"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU9743796.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMAFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(45307..46185)
                     /gene="mvk"
                     /locus_tag="VW361_000703"
     CDS             complement(45307..46185)
                     /gene="mvk"
                     /locus_tag="VW361_000703"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU9743797.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVS
                     AESPWRLYEEDTLSMAVYASLEYLDITEACVRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETALSYGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(46307..46636)
                     /locus_tag="VW361_000704"
     CDS             complement(46307..46636)
                     /locus_tag="VW361_000704"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9743798.1"
                     /translation="MTRKVYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYFVN
                     YNGEWVQ"
BASE COUNT        13622 a        10784 c         8882 g        13518 t
ORIGIN      
        1 ttctatttta acgtttattt atgaatgtta tttttgtttt tattaaaaag ataccgattt
       61 catttactaa aaaagaaaaa agaactgatt tctcagtcct tcattaatct tattccacac
      121 taaataggta tgggtaaaca ggttgttgac cttggtgaat ctcgacttca acgtcttcga
      181 attcttctac gatttcttga gcgatttcat tggcaagttc ttcgcttccg tcttcaccga
      241 catagaaggt tacgatttca ctgtcttcat ccaacatatg tttcaaggtt tcagtcaatg
      301 tttggtgcat atcagggttt gacacaagaa tttttccatc caccatacct agattatcgt
      361 tttcatggat ttctaagcca tcgatcgttg tatcacgcac ggctgttgtg acgcttccgc
      421 taacaacatc gctaagagca gctgtcatac gctcttggtt ttcttcaatg gacttgcttg
      481 gatcaaaggc aagaagactt gtcatacctt gaggaagagt gcgagcctct accactactg
      541 ctggttgctc caaaacttct gccgcagatt gagctgccat gaagatgttc ttgttgtttg
      601 gcaagaagat gatgttacgg gcattgacct gttcaacagc cttgataaag tcttctgttg
      661 aagggttcat ggtttgaccg ccttcgataa cataatccac gccttgagaa cagaagatat
      721 ctgctagacc tttaccagcc accacagcaa tcaaagcata ctctttttct tcagccgact
      781 tgataacttg agtagcttct ttctcaacct gtgcttcgtg ttggttacgc atattgtcaa
      841 cttttacctt gaccaagcta ccatatttga gaccttcttg cataacaagt cctggatctt
      901 ctgtatgaac atggactttg acaatttcat catcgttaac aacgaggaga gaatccccaa
      961 gctcatccaa gtagttacgg aattcatcgt agtcaaaatc tttagcatag gttggacctt
     1021 gcttaagagc taccatgatt tcagtacagt aaccaaacgt gatgtcctca gtcgctacgt
     1081 gaccagctac agacttatga tgctctacat tgatcatctc actcatgttg gcaggagtcg
     1141 ctacaaagtc ctcagatgca atatattcgc cagtaagggc tgaaaggaaa ccttcgtaga
     1201 tgaagaccaa tccttgacca cctgagtcca caacgccaac ttctttcaat actggaagca
     1261 tgtctggtgt tttagctaga gctgttttag caccttccaa ggctgcgcgc atgacttcaa
     1321 cagcgtcatc tgtttgctca gcttttttct tagcaccgat agcagctcca cgagaaactg
     1381 ttaaaatcgt tccttcaaca ggtttcatca ctgccttata ggcaacttcc acacctgatt
     1441 ggaaggccag agccaagtct tgacctgtta actcgtcttt atccttgata gcttgggaaa
     1501 atccacggaa aagctgagac gtaatcactc ctgagttccc acgcgcaccc atcaaaagcc
     1561 ctttggcaag aatgctcgct acttctccaa ctgtagaagc tggcttgtct gcaacttctt
     1621 tagcaccatt ttcaatggtc attcccatat ttgtcccagt atctccatct ggaactggaa
     1681 agacgtttaa tgaattgaca tattcagctt gcttattcaa gcgagttgat gcagcctgca
     1741 ccatttcttg aaataagcta gtagtaattt ttgacacggt tattctccta caactttgat
     1801 attttgaatg tagacattta cagtctgagc agtaattcca agctggtttt ccaagctaaa
     1861 ggcaacacgc tcttgaatgt tttttgacac ttcactaatc tttgttccgt agcttaacac
     1921 ggtatataca tcaactgcaa tactgccatc ttcggctgcc tttacgacga cacctttaga
     1981 ataattttcc ttacctagca gggcttggaa attatctttg agggcatttt tactagccat
     2041 accgaccaca ccaaaaatct cagttgctgc tccacctacg acggttgcaa tcacttcatc
     2101 tgttagttcg atttgaccat cttttgtatt aatttttaca gtcatccttt ttacctcaac
     2161 tagttgatac tctattttat catatttcag cccaagtgta aaagcagaat gatgtatcag
     2221 cggatattta ctctattttt caaacgatgt tatacccaca ataaaagaaa aaagacccta
     2281 aggtctcctt tgcttttatt attaaacgcg ttcaacttta cctgatttca aagcacgagc
     2341 tgaagcccaa acttttttag gtttaccatc gataagaaca gtaacttttt gaaggtttgg
     2401 ttttacggca cgttttgttt ggttcatcgc gtgtgaacgg ttgtttcctg atacagtctt
     2461 acgacctgta aagtaacata ctttagccat tgtgttttcc tcctattaga tctaatatag
     2521 cggatgtgct agcaccacat accgtactat gttatcacac tttcttgttt tttgcaaggg
     2581 aattggaaga ttttttattt gtgtcttaaa tcaggtcttg cgtgacattt tctgctctcc
     2641 acatgccatt gttgattaac agaacaccag aattaaaatt atgtgtataa aaatcatctc
     2701 taactgcagc taagggtata gccgtcaagt ccaaatccca cagctcatct atcgattttc
     2761 ttacaacaat atctgaatcc aaatacagta cacgagactc gcttacatac tttggaataa
     2821 aatacctaaa aaaagccgca tatgaaagtc cctcaaaggg gagacgataa cctttcagaa
     2881 tactactgtc aatctgaaca ttcacaatct cactattcaa agtctctagt cttttttcca
     2941 tcaattggaa ccattctcgc ggaaggtcat cattaaaaac ataaaactta agattataat
     3001 gatgaacaca aagagatttt attgttgttt caactttatc catataagca ttatctgcac
     3061 ctaagacaat cgcttttttc tcttctttca ctctttatct catttctttt tattcccatc
     3121 atatgtttct acgtaaccat tattttcgcc cattcgttcg taaaaccata ccagtggaga
     3181 ttttagatga agtcccatta cggtttacaa tttttacatt acgacacgga gttttacaaa
     3241 tcgatttcat ttgccaaacg tagttagtaa ggcaattagc taggctacct actttctgct
     3301 acgacggaaa aatccacaaa tcaataccat tcgtggattt ttcctagtga agcgtttagg
     3361 taagccgcca tagcggttac cgattattag attacgacac ggagtttggc aaatcgattc
     3421 tatttgccaa acgtagttag tgaggcagtt agctagttcg ccaaatagcg actagcgtcc
     3481 aacaatttgg aactttagtt ccaattgttg gtactgagtc acatcttctc ctctaactct
     3541 acgtctggat acttgtccgc aaaccagcgg agggcaaagt cattttcaaa gagaaagact
     3601 ggttggtcaa aacggtcttt ggctaagata ttgcgacttg acgacatccg ttcatccaag
     3661 tcctcaggct tgatccaacg aacggtcttt ttacccattg gggtcataac tacttccgca
     3721 ttgtactcgc cttccatgcg gtgtttaaag acttcaaact ggagttgacc tacagcgcct
     3781 agcatgtact cacctgtttg gtaattctta taaagctgaa cggctccttc ttgcaccaat
     3841 tgctcaatcc ccttgtggaa ggatttttgc ttcataacat tcttagcaga aactttcatg
     3901 aaaatttcag gagtaaaggt tggcaggggt tcaaattcaa acttgttttt tccaaccgtc
     3961 aaggtatccc caacctgata agtaccggta tcgtaaaccc cgataatatc acctgccacg
     4021 gcattggtca cattctcacg actctccgcc ataaactggg taacattaga tagtttggcc
     4081 cccttaccag tacgaggaag attgacactc atgccacgct caaattcgcc tgatacgata
     4141 cgaacaaagg caatacggtc acggtgacga ggatccatgt tggcttggat tttaaagaca
     4201 aagcctgaga aatccttgtc ataaggatcc acaatttcac cgtctgtttt cttgtgacca
     4261 tgtggttctg gagcaaactt gaggaagatt tcaaggaagg tctgcacacc aaagtttgtc
     4321 agggctgaac cgaaaaagac aggcgtcaat tctccagcca gaatagcttc ctctgaaaac
     4381 tcattcccag cttcatttaa aagctcaatg tcatccttga cttgctcgta gaaaggattg
     4441 ctaccaaaaa gtttgtctcc atcttctagg ctagcaaaac gctcatcccc tttataaagt
     4501 tctaaacgtt ggttatagag gtcatacaag ccctcaaagg ctttccccat cccgataggc
     4561 cagttcatag ggtagctagc aatgcccaag atttcttcca attcttgcaa gagttccaaa
     4621 ggctcacgac cgtcacggtc cagcttgttc ataaaggtaa agactggaat gccacgatgt
     4681 ttcacaacct caaacaattt cttggtttga gcctcgatcc ccttggcaga gtccacgacc
     4741 atgaccgcag catccaccgc catcaaggta cgataggtat cttctgagaa gtcctcgtgc
     4801 cctggcgtgt ctaagatatt cacgcgcttg ccgtcgtagt caaattgcat aacagatgaa
     4861 gtaacagaaa tcccacgttg cttctcgata tccatccagt cagatttagc aaaagtccct
     4921 gttttcttcc cttttaccgt accagcctca cgaatctcac ccccaaagta gagtaactgc
     4981 tcagtgatgg ttgttttccc cgcgtccggg tgggagataa tggcaaaggt acgacgtttc
     5041 ttaatttctt cttgaatatt cataagttct ctttctttga ttctctattt ttcttgtttc
     5101 aatagctgag aatgattttt acattggatt ttaccattcc tttcaacact ccattatatc
     5161 ggattttagc atttttttca atttctattt cttttcactt ccccctccct tatttatagg
     5221 aaaatatggt aaaatagaac agactaaaaa tcatcatttc acgaaaggat gcaagatgaa
     5281 aattacgcaa gaagaggtaa cacacgttgc caatctttca aaattaagat tctctgaaga
     5341 agaaactgct gcctttgcga ccaccttgtc taagattgtt gacatggttg aattgctggg
     5401 cgaagttgac acaactggtg tcgcacctac tacgactatg gctgaccgca agactgtact
     5461 ccgccctgat gtggccgaag aaggaataga ccgtgatcgc ttgtttaaaa acgtacctga
     5521 aaaagacaac tactatatca aggtgccagc tatcctagac gatggaggag atgcctaatg
     5581 acttttaaca ataaaactat tgaagagttg cacaatctcc ttgtctctaa ggaaatttct
     5641 gcaacagaat tgacccaagc aacacttgaa aatatcaagt ctcgtgagga agccctcaat
     5701 tcatttgtca ccatcgctga ggagcaagct cttgttcaag ctaaagccat tgatgaagct
     5761 ggaattgatg ctgacaatgt cctttcagga attccacttg ctgttaagga taacatctct
     5821 acagacggta ttctcacaac tgctgcctca aaaatgctct acaactatga gccaatcttt
     5881 gatgcgacag ctgttgccaa tgcaaaaacc aagggcatga ttgtcgttgg aaagaccaac
     5941 atgaacgaat ttgctatggg tggttccggt gaaacttcac actacggagc aactaaaaac
     6001 gcttgggacc acagcaaggt tcctggtggg tcatcaagtg gttctgccgc agctgtagcc
     6061 tcaggacaag ttcgcttgtc acttggttct gatactggtg gttccatccg ccaacctgct
     6121 gccttcaacg gaatcgttgg tctcaaacca acctacggaa cagtttcacg tttcggtctc
     6181 attgcctttg gtagctcatt agaccagatt ggaccttttg ctcctactgt taaggaaaat
     6241 gccctcttgc tcaacgctat tgccagcgaa gatgctaaag actctacttc tgctcctgtc
     6301 cgcatcgccg actttacttc aaaaatcggc caagacatta agggcatgaa aattgctttg
     6361 cctaaggaat acctaggcga aggaattgat ccagaggtta aggaaacaat cttaaacgcg
     6421 gccaaacact ttgaaaaatt gggtgctatc gtcgaagaag tcagccttcc tcactctaaa
     6481 tacggtgttg ccgtttatta catcatcgct tcatcagaag cttcatcaaa cttgcaacgt
     6541 tttgacggta tccgttacgg ctaccgcgca gaagatgcga ctaatcttga tgaaatctat
     6601 gtaaacagcc gtagccaagg ttttggtgaa gaagtgaagc gccgtatcat gctgggtact
     6661 ttcagtcttt catcaggtta ctacgatgcc tactacaaga aggctggaca ggtccgtaca
     6721 cttatcattc aagatttcga aaaagtcttc gcggattacg atttgatttt gggtccaact
     6781 gctccaagtg ttgcctatga cttggattct ctcaaccatg acccagttgc catgtactta
     6841 gccgacctct tgaccatacc tgtaaacttg gcaggactgc ctggaatttc gattcctgct
     6901 ggattctctc aaggtctacc tgtcggactc caattgattg gtcccaagta ctctgaggaa
     6961 accatttacc aagctgctgc tgcttttgaa gcaacaacag actaccacaa acaacaaccc
     7021 gtgatttttg gaggtgacaa ctaatgaact ttgaaacagt catcggactt gaagtccacg
     7081 tagagctcaa caccaattca aaaatcttct cacctacttc tgcccacttt ggaaatgacc
     7141 aaaatgccaa cactaacgtg attgactggt ctttcccagg agttctacca gttctcaata
     7201 aaggggttgt tgatgccggt atcaaggctg ctcttgccct caacatggac ctccacaaaa
     7261 aaatgcactt tgaccgcaag aactacttct accctgataa tcccaaagcc taccaaattt
     7321 ctcagtttga tgagccaatc ggttataacg gctggattga agtcgagcta gaagacggta
     7381 cgaccaagaa aattggtatc gaacgcgccc acttagagga agacgctggt aaaaacaccc
     7441 acggtacaga cggctactct tacgttgacc ttaaccgcca aggggtacct ttgattgaga
     7501 ttgtatctga agccgatatg cgttcgccag aggaggccta tgcttatctg acagccctca
     7561 aggaagttat ccagtacgct ggcatttctg acgttaagat ggaagaaggt tctatgcgtg
     7621 tggatgccaa catctccctt cgcccttatg gtcaagaaaa attcggtacc aagactgaat
     7681 tgaagaacct caactccttc tcaaacgttc gtaaaggtct tgaatacgaa gtccaacgcc
     7741 aggctgaaat tcttcgctca ggtggtcaaa tccgccaaga aacacgccgt tacgatgaag
     7801 ctaacaaaac aaccatcctc atgcgtgtca aggaaggggc tgctgactac cgctacttcc
     7861 cagaaccaga cctacccctc tttgaaattt ctgacgagtg gattgaggaa atgaggactg
     7921 agttgccaga gtttccaaaa gaacgtcgtg cgcgttatgt atctgacctt ggtttatcag
     7981 actacgatgc tagtcagttg actgctaata aagtcacttc tgacttcttt gaaaaagctg
     8041 ttgccctagg tggtgatgcc aaacaagtct ctaactggct ccaaggggaa gtcgctcagt
     8101 tcttgaatgc tgaaggtaaa acactggaac aaatcgaatt gacaccagaa aacttggttg
     8161 aaatgattac catcatcgaa gacggtacta tttcatctaa gattgccaag aaagtctttg
     8221 tccatctagc taaaaatggc ggtggcgcgc gtgaatacgt ggaaaaagca ggtatggttc
     8281 aaatttcaga tccagctgtt ttgattccaa tcatccacca agtctttgcc gataacgaag
     8341 ctgctgttgc cgacttcaag tcaggcaaac gtaacgccga caaggccttt acaggattcc
     8401 ttatgaaggc aaccaaaggc caagccaacc cacaagttgc ccttaaacta cttgcacagg
     8461 aattggcgaa gttgaaagaa aactagatag aacaaaacca gccctaaggt tggttttttc
     8521 ttctctacca actcccaata actattttgg ctttatttcc agagtatttt atggtaaaat
     8581 gaagagtaat aatatttatt aaagaggtaa aaacatgatt gaagcaagta aattaaaagc
     8641 tggtatgacc tttgaaacag ctgacggcaa attgattcgc gttttggaag ctagtcacca
     8701 caaaccaggt aaaggaaaca cgatcatgcg tatgaaatta cgtgatgtcc gtactggttc
     8761 tacatttgac acaagctacc gtccagagga aaaatttgaa caagctatta tcgagactgt
     8821 cccagctcaa tacttgtaca aaatggatga cacagcatac ttcatgaata cagaaactta
     8881 cgaccagtac gaaatccctg tagtcaatgt tgaaaacgaa ttgctttaca tccttgaaaa
     8941 ctctgatgtg aaaatccaat tctacggaac tgaagtgatc ggtgtcaccg ttcctactac
     9001 tgttgagttg acagttgctg aaactcaacc atctatcaaa ggtgctactg ttacaggttc
     9061 tggcaaacca gcaacgatgg aaactggact tgtcgtaaac gttccagact tcatcgaagc
     9121 aggacaaaaa ctcgttatca acactgcaga aggaacttac gtttctcgtg cctaatctct
     9181 agaaagaggt cattctatgg gaattgaaga acaacttggc gaaatcgtta tcgccccacg
     9241 tgtacttgaa aaaatcattg ctattgctac tgcaaaggta gagggtgttc actctttttc
     9301 aaacagatca gtgtctgata ccctttcaaa actttcactc ggccgtggca tttatcttaa
     9361 aaacgtggac gaagaactca cagcagatat ctatctctac cttgagtacg gagtaaaagt
     9421 tcctaaggta gcggttgcta tccagaaagc tgtcaaagat gccgtccgta atatggctga
     9481 tgtagaactc gctgctatca atattcacgt tgcaggtatc gtcccagata aaacaccaaa
     9541 accagaattg aaagatctat ttgacgagga cttcctcaat gactagtcca ctattagaat
     9601 ctagacgcca actccgtaaa tgcgcttttc aagctctcat gagccttgag ttcggtacgg
     9661 atgtcgaaac tgcttgtcgt ttcgcctata ctcatgatcg tgaagatacg gatgtacaac
     9721 ttccagcctt tttgatagac ctcgtttctg gtgttcaagc taaaaaggaa gaactagata
     9781 agcaaatcac tcagcattta aaagcaggtt ggaccattga acgcttaacg ctcgtggaga
     9841 gaaacctcct tcgcttggga gtctttgaaa tcacttcatt tgacactcct cagctggttg
     9901 ctgttaatga agctatcgag cttgcaaagg acttctccga tcaaaaatct gcccgtttta
     9961 tcaatggact gctcagccag tttgtaacag aagaacaata aaaagaaaaa gtgtttgata
    10021 tctatcaaac actttttctt tgcctcccac tatctaaaaa aatgataata gatataattg
    10081 taaacaaaaa tccagatagg ttttgcatga ttgagaaagt taaaaaaact atggcagaga
    10141 atcgttaatc tcagattgtc ggtagaacga taaacaaggg caaaaaagaa accaatcaga
    10201 ctataatata ataaactaat tggatctctg tgagatagta tcaaatggct aatcccaaag
    10261 ataaggcctg ataagatgac atctaaatag tactttgact taggaaagaa ggtattcata
    10321 aaataccctc tatcaagagt ctcctcaaaa aaatgagcat agcgtgccta aaaattaccg
    10381 agaatctgat aaaccacata agttgcaaat aagtagaaga caaatgacca gttccagctc
    10441 tttttttcaa agataaagag catctttttc ttttttaacc tccaaattaa tagaaggaaa
    10501 cttcccacta ataccattgt taaaataaga gaatagacat cagctcctaa ccctaaaatg
    10561 atcgtcacat acaatccaat tgtttgtggt aaataggtag atagtaaaat aataagcaaa
    10621 aatattccaa attgtcttag tttctttgtg tttctcatcg tacttttttg aaagattacc
    10681 ctgctcggaa gccgtacttc caagcatcta tataagaatt aagtgcccct tgcctcatat
    10741 agggagcaaa ttctctataa tataaccatc tactatatcc atcttcccaa acagcaagac
    10801 cacctgaagt ttgctccaag tcctcagttg aaagaactgt aaatgtattt gtacctgtca
    10861 ttgcaagtac cttcttaaaa tagattgttg taggctcaca tttatagtat atttcttttt
    10921 ttgtctattt tatagctcat ctcctcaact ggcaattttt cgacctgaat tgcatttttc
    10981 cataaaaaat gagacctttc tagtctcatt tagtcattct tagtattttc taaatcgttg
    11041 atagcgttct tccagcaact cttctagcgg tttttgtgaa agtctagcca gctccgtttg
    11101 gagttctttt ttgacactct taatcagttc tttactagaa agtcctactt cagaaatcac
    11161 cttatccacc acgtccattt ctaacagttc atgcgaagtg attttcatca gttctgctgc
    11221 ttccatggcg cgagtaccgt ccttccataa aatggaagca aagccttctg gactgagaat
    11281 ggcatagata gaattttcca gcatccagac acggtccgcg acagctagag ccagagcccc
    11341 gcctgaacca ccttcaccga taataatggc gataatagga actttcaggt cactcatttc
    11401 catgagattg cgagcgatag cttccccttg accacgttct tccgctccga caccaggata
    11461 agcacctgct gtattgataa aggtcacaac tggacggcca aatttctcag cctgtttcat
    11521 caaccgcagt gcctttcggt agccttctgg atgtggttgg ccaaaattcc gtttgaggtt
    11581 gtcttgcaaa ctcttgcctt tttggatacc aaccactgtt acagcttggt ctccaagcca
    11641 accaatacca ccaacaactg caccatcatc acgaaaagaa cggtcaccat gtaattggat
    11701 aaattcatca aaaatgcctg tcgcaaagtc caaggttgtc aagcgactct gctcacgcgc
    11761 ttctctgact atttttgcaa tattcatcta ggactccctc catgcaatct gactaggcta
    11821 gcaatcgtat ctggtaagtc tcttcttttg acaatagcat ccacaaagcc atgttctaat
    11881 aggaattctg ccttttggaa atcctcaggc aagctttcac gaaccgtatt ttcaatcaca
    11941 cgacgcccag caaaaccaac caagctctgt ggttcagcca gaatgatatc gccttccata
    12001 gcgaaagaag ctgtcacacc accagtcgtt ggatctgtca aaatggtcag gtaaaagaga
    12061 ccagcatttg aatggcgttt aaccgccgca gagatcttag ccatctgcat gagactcatg
    12121 attccttcct gcatacgggc tccaccagag gctgtgaata ggacaactgg caatttttcg
    12181 acagtcgcat actcaaacaa acgagtgatt ttttcaccta caaccgtacc catagaagcc
    12241 atgataaagt tagaatccat aatcccaaga gccacagtct gacctttaat aagagcagtt
    12301 cctgtcacaa cggcttcatg cagacctgtt ttttcacgca tagatgccag tttcttttgg
    12361 taaccaggga aatgcaaggg atccttgctt tcaatccctg taaacaattc tttgaaggtt
    12421 cccatatcaa tcgtcaaagc caagcgttct tgggcagaaa tacgaaaggt atagctacag
    12481 tgcggacaga tacgttcact tcccagatcc ttctgataga tggtatgctt acagcctgga
    12541 cactgggaaa ataattcatc tggaacctct ggcttagctt gaggtttttc cctaaccgaa
    12601 cgattgggat tgattcgaat atacttatct tttttactaa atagagccat tgattcccct
    12661 tttcggttta aactcttaaa gtcattttat tctttttctt gatatttagg taagaaggtt
    12721 tccatcaaga aggaagtatc ataatcccca gcaatgacat tgcgatctga aatgaggtca
    12781 agctggaaat ctgcattggt ctgcactcct tcaatctcta attcatagag ggcacgttgc
    12841 attttcatca aggcgtcaaa acgattttcg ccgtgtacta tgattttggc aatcatacta
    12901 tcataataag gcggaatggt ataacctgga taaactgctg aatccacgcg caagccaact
    12961 ccaccacttg gcagatagag attagtaatc ttacctggac ttggagcaaa gttaaaggct
    13021 gggttttctg cattgatacg acactcgatg gcatgaccgc gtaggacaat atcttcttgc
    13081 ttaacagaca aaggctgacc tgccgcaatg caaatctgtt ccttaacgat atcaacacct
    13141 gaaacaaact ctgttactgg atgttctacc tgaacacgag tattcatctc catgaaatag
    13201 aaattgctac ttgcttcatc aagaagaaat tcaatggttc ctgcattctc atagccaaca
    13261 aactctgccg ctcgaacagc agcagcacct atttcatgac gcagcgtttt tccgattgca
    13321 atcgagggac tttcttccaa aaccttttgg ttattccttt gaagagaaca atcccgttca
    13381 cccaagtgaa tcacatgtcc atgctcatca cctaggattt gaacctcaat gtgccgagct
    13441 ggatagataa cccgttctat gtacatggca ccattgccat aattggcctt ggcctcacta
    13501 gaggcagttt caaaggcaga aacgaggtca tctggttttt caaccttacg aatcccttta
    13561 ccacctccac ctgctgaagc cttgagcata acaggatagc caattttttc agcaacaatc
    13621 aaagcttctt cagagttatg cacttctcca tctgaacctg gtataacagg cacacctgct
    13681 ttaatcatct gagcacgcgc attgatctta tcccccatca tatccataac atgaccagat
    13741 ggaccgataa acttgatacc tacttcttca cacatggtcg caaatttgga attttcactg
    13801 agaaatccaa aaccagggtg aatagcttct gcctcagtca agactgcagc tgatagaact
    13861 gcattaatat tgagataaga ctctgttgcc ttgccaggac caatacaaac tgcttcatct
    13921 gccaaaagcg tatgaagagc ttccttatca gcagttgaat aaaccgctac cgtcgcaatc
    13981 cccaattcac gtgccgcacg gataatacga accgcaattt caccacgatt ggcaattaaa
    14041 atttttcgaa acatggagaa cctccttagt tcccaattgc aaaagtaagg ataccactgg
    14101 ctgcaagctt gccatccact tcagcctttg cttcaaccac agctatggtg ccacgacgtt
    14161 ttacaaaagt cgctgtcata accaattggt cgcctggtac aacttgcttc ttgaacttaa
    14221 ccttgtccat accagcgtaa aagaccagtt ttcctttatt ttcaggtttt gataactcta
    14281 acacaccagc agtttgcgcc aaggcttcca taatcagaac acctggcata actgggtatt
    14341 gaggaaagtg gccgttaaag aaaggttcgt taatggtcac atttttgata gcaacaatgg
    14401 tatcctcgct cacttccaag acacggtcca ctagaagcat aggataacgg tggggaagag
    14461 cttctttgat tccttgaata tcgatcattt gatacgtacc aatcctttac caaactcaac
    14521 catttcttcg ttagagacga gaatttccgt taccacacca tccttaggag ctgggatttc
    14581 attcatgact ttcatggctt cgataattac caatgtttga ccttttttga cactatcacc
    14641 aactgtaacg aaggcaggtt tatctggtcc agcagccaag taaaccactc caacaagtgg
    14701 actctctaca agatttccct cagtagccac acttgcttca gctggagctg gaacttcttc
    14761 tgctacagtc tctgctggag cagatgtagg agctactgga ctcggtgttg ctagaacggg
    14821 tgctggagcg acttgagttg caacttcagg cacaggtctc gcttcattct tgctaaactg
    14881 caactcatcc gtcccatttt tataagaaaa ttctctcaaa cttgactggt caaattgagt
    14941 catcaagtct ttaatatcgt ttaaattcat acttatctat tctcccaacg tttgaaagca
    15001 agaactgcat tgtggcctcc aaaaccaaaa gtatttgaaa tagcgtatgg aatttctttc
    15061 tccaagcctt gtccataaac gacattagct tcgatataat ctgatacttc acttgtccca
    15121 gctgtcattg gtacaaagtt atggcgcata gcttcgatgg tgacgatagc ttctactgca
    15181 cccgcagccc ccagcaaatg tcctgtaaaa gacttggttg atgatacagg tacttcctta
    15241 ccaagaacag ctacgatagc accactttct cctttttcat tggcaggagt tgacgttccg
    15301 tgagcattga cataggctac ttgctctgga gaaatctcag cttcttccaa ggctagtttg
    15361 atggccttga tagctccctg accttctgga tgtggagaag tcatgtggta ggcatcacaa
    15421 gtatttccgt aaccaaccac ttcagccagg atagtagctc cacgtttttc agcgtgttca
    15481 agactttcta aaaccaacat ccctgaacct tcacccataa caaacccatt gcgatcctta
    15541 tcaaatggga tcgaagcacg agttggatcc tctgtagtag agagagctgt taaggcttgg
    15601 aaaccagcga tggcaaaagg tgtgatagaa gcttctgttc ctcccaccaa catcacatct
    15661 tggaaaccaa acttaatgga gcggaaggca tccccaatcg catcatttga tgaagagcag
    15721 gcagtattga tagatttaca aacaccgttt gcaccaaaac gcatggctac attcccagaa
    15781 gccatatttg gtaaagcttt tggaagagtc attggtttga cacgtttggg tcctttttca
    15841 tgaaggcgaa gtacctgatc ttcaatttcc ttgattccac caataccaga tgcaacgata
    15901 acaccaaaac gatccctatt aagagcctct acatcaagat tggcatgatt tacagcctct
    15961 tgggctgcat acaaggcata taaagaatag ttatcaaaac ggttggtatc tttttttaca
    16021 aagtatttat cgaacggaaa atcttggatt tctgccgcat tatgcacatc aaagtcacta
    16081 tgatcaaatt ttgtaatgcc accaatgccg attttcccag ttgctaaact attccaaaat
    16141 tcttctggtg tatttccgat tggagatgtt actccataac ctgttaccac tactcgattt
    16201 agtttcattc ttttcacctc tagctttcgc tacatactta agccaccatc aatggcaacc
    16261 acttgaccag ttagataatc ttggcctgct aaaaatactg tcaaatctgc aacctgctct
    16321 gcctgcccaa attctttcat cggaatctga gctagtgtag cttccttaat cttatctgat
    16381 aagatagctg tcatatcaga ctcaatcatt cctggagcaa tcacattgac tcgtatattc
    16441 cgactagcga cctcgcgtgc cacagacttg gtaaagccaa tcaagccagc cttagaagca
    16501 gcatagttag cttgaccaat attccccatc aaaccaacaa cactagacat attaatgata
    16561 gcaccttctc tggctttcat catcggtttc aagactgatt gtgtcatatt aaaggcacca
    16621 gtcagattga ccttgagcac tttttcaaaa tctgcttctg tcatcttgag cataagagta
    16681 tcttgggtaa tccctgcatt gttgaccaaa acatctactg aacccagttc tgcaatagct
    16741 tgatcaatca tacgcttagc gtctgcaaaa tctgatacat ctcctgaaat gggaaccacc
    16801 ttgataccat agtttgaaaa ctcagcgagc aattcttctg agattgcccc acgactgttt
    16861 aagacaatgt tggctcctgc ttgagcaaac ttgtgggcga tggcaagacc aattccacga
    16921 ctcgaacctg taataaagat atttttatgt tctagtttca tttttttcct ttcaaaactt
    16981 ctacttattt tagtctattt ttctaaaagt gctactaaac tcgcttgatc ttccacatga
    17041 gctaagtgag cagtttgatc aattttttta acaaaacctg acaagacttt ccccggtcca
    17101 atctcgataa agttgcttat gcctgcttct tgcatgaccc caatactttc atagaaacga
    17161 acgggttcct tgacctgacg cgtcaagagc tgagcgatgt cctctttttg catcacagca
    17221 gcttctgtat tgccgactag gggacaagta aaatctgaaa aacttacctg agctagagtt
    17281 tcagctagtt tctggctagc aggctcaagg agagcggtgt gaaagggacc tgacacctta
    17341 agaggaatca agcgtttggc acctgcttct tgcaaaagtt caaccgctcg atcaactgca
    17401 accacttctc cagcaatgac gatttgtgca ggtgtgttat agttggctgg agtaaccact
    17461 ccaagttcag aagctttttg acaggcttct tcaatgacct ctactggcgt attgagaact
    17521 gctaccatct tgccagagtc agcaggagcc gcttcttcca tataggctcc acgcttagct
    17581 accaaggcaa ccgcatcttc aaaatccaag gcgccgcttg ccaccaaggc agagtattct
    17641 ccaagagaca aaccagcaac catatcaggc tgatagccct tttcttgcaa taaacggtag
    17701 atagcaaccg aagtcgctag aatggctggt tgcgtatagc gggtctgatt gagtttgtct
    17761 tcttccgtat cgatgagata acgtaaatca taaccgagca cctgactcgc tcgatcaatc
    17821 gtttctttga caatcggata ctgatcatag aaatcccgtc ccatccctag atactgggca
    17881 ccttgaccag caaataaaaa ggctgtttta gtcatttctt acaactcctg cccagcgaga
    17941 ggcttcttct tgaattttct tagcggctcc gtaatacaaa tcttttagga tttcttcagc
    18001 tgtttcttct ttagaaacaa gccctgcgat ttgacctgcc atgacagagc caccctccac
    18061 atcaccgtga acaactgctt tggctagggc acctgctccc atttgttcaa agatttctaa
    18121 atcaggatct tcctgcttaa aggcatcttt ttcagccagt tcaaaatctc tagtcaactg
    18181 atttttaata gcacgaacag catgaccaaa gtgctgagct gaaatcgtag tgtcaatatc
    18241 ccttgctttt aaaattttct ccttgtagtt tggatgggca ttcgactctt ttgcaactac
    18301 aaaccgtgtc cccacctgta cagcctctgc acctagcata aagccagccg cagcaccttc
    18361 accatccgca attcctcctg cagcaataac aggaatagat acagctgtgg ctacctgtcg
    18421 caccaaggtc atggttgtta atttaccgat atgcccccca gcttccattc cttctgcaat
    18481 aacagcgtct gcaccgattt tttccatgcg tttagctaaa gcgacactag gaacaacagg
    18541 aataacgatt atcccagctt catggaaacg ttccatatac ttgcttggat ttcctgctcc
    18601 tgttgtgaca actttaacac cttcttcaat aacgagatcc acgatatctt ccacaaaggg
    18661 agataagagc atgatgttga ccccaaaggg tttatcagtc aatgatttga ttttatcaat
    18721 attggccttg acaacttctt tcggggcatt tcccccaccg ataattccta atcctccagc
    18781 cttggaaaca gcccctgcca aatcaccatc agcaacccag gccatccctc cttggaaaat
    18841 aggatagtca atcttcaata attctgtaat acgcgttttc atagtgcctc caaccttcct
    18901 tgcttacgta atagttcgat ttcaccataa tttgacagtc aaactattac ctaaacaaga
    18961 gggagtgggt ttctccctac tccttctact aatattctgc ttattttgct tgctcttcaa
    19021 cgtaagcaac caagtcacca actgttttca agtcattttc tgcttcgatt tggatatcaa
    19081 aagcatcttc gatttctgag attacttgga acaagtccaa tgaatctgcg tccaaatcat
    19141 caaaagttga ttcaagtgtt acttctgatg cgtcttttcc aagttcttca acgataattt
    19201 cttgtacttt ttcaaatact gccatgatag gactccttta aaataaatag ttttttataa
    19261 caatgtgttc accacatgat tacctaaatt gtaagaatga gcgtgcccca ggtcaagcct
    19321 ccaccgaagc ctgatagaag aacagtctgg ctaccatcta aagggatgag accttgttct
    19381 acacactctg aaagtaaaat cgggatactg gctgcactgg tattgccata ttccatcata
    19441 ttggctggaa gtttggctcg gtcaacacca atttttctag ccatcttatc caaaatacgg
    19501 tcattggctt gatgaagtag cagataatcc aagtctgtca cctctatagg agattcatca
    19561 atagtctgct tgatagactt ggctacatct cgaatggcaa aatcaaagac tgtgcgtcca
    19621 tccatcttca aaaatgaatc tgcactttct tgatctgaaa atggagaatg caaacctgaa
    19681 tgcccataag ttaaacactc gctgcgactt ccatcgctat tgagactctc agctaagaaa
    19741 tgctcttgct cgctagcttc taacaagaca ccaccagcac catctccaaa caacacagct
    19801 gttgatcgat ccgaccaatc gactgcctta gagagggttt cactaccaat caccaagcct
    19861 ttttgaaagc gaccagaagc gataaacttt tcagcagttg aaagagcaaa tacaaatcca
    19921 ctgcaagccg cggttaagtc aaaagcaaag gctttattag caccaatatt agcttgaaca
    19981 cgagcagctg tagagggcat catcgaatct ggagtaatgg tagctaggat gataaaatcc
    20041 agttcttctc ctgttattcc agcttttgcc atcagtttct tagcaacctc tgtagccaaa
    20101 tcactggtag attctgttct tgaaatatgc ctttgtcgta ttcccgttcg acttgaaatc
    20161 cactcatcat tggtatccat aatctgagcc aagtcgtgat ttgtaaccac ttgctctggc
    20221 acataatgag caacctgact tatttttgca aaagccatta tttcaaatcc tccaaaaatt
    20281 ggtaaagatt agtcaagcct ttacccatga cagcaatttc ttcctcgctc atgccatcaa
    20341 taattttttc taccatggcc ttgtggaagc gtttatgcag cctatgaatc aagcgaccct
    20401 tctttgtcaa atgcagatgc accacacgac gatcctgttc tgaccgaact cgctcaatgt
    20461 agcccttacg ctctaaattg ttcaaacttg tcgtaacagt tccaagagtt accatcaact
    20521 cttttgacac ttgacttgga gtcacatctg gagccttacc gatgacatca atcgtatgca
    20581 tttctttgat ggagatatcc ttaaaacgac tacctctcaa gttcacttcc tcaattacaa
    20641 ggacattgtt aaatatagat gttaaatatt cattgattcg ttggtagtcc atttttcata
    20701 tccctccttc ttcaaaaaac ttttacaatc aaaacatttg acagaaagaa ttatatcaaa
    20761 attcaaagaa tgatgcaagt attttttact ttcctgtaaa tttaggtctt cttctctccg
    20821 aatgagctcg cactccttct ttgaaatcct ctgtttgagc taaggatttc tgtaggttca
    20881 gttctaaagt agcgtaaccc tgccagtctt taaattggct ctcccaaacc aacttcttaa
    20941 tggcagcata ggaattactt gaagcacgtc ttaatttttt aagaagctgt tctctcgtct
    21001 tttcaagttt ttcagcttca gaaacgcggt aaaccaaccc ccattctagg gctttttctg
    21061 ccgttaaagc ctctcctgtc atagctaatt gagcagcacg cgtcacaccg atactgcggc
    21121 tcaagagatg aattccccct gcatctggag ccaaaccaac accaacaaag gcttggataa
    21181 acttagcctt atccgtcgcc aaacagaaat ctgccgcaac agccatattc gctgcggcac
    21241 ctgcaacagc accgtcaact tccattaaaa caggtttggc tatttgcttg attttataag
    21301 aaatcgtatt gaccaactct gcgatttttg tcaatgatgg aatatcatcc tcatccactg
    21361 cccgcttcat ctctaccaaa tctcccccaa ctgagaagac ctttccattg gcattgatta
    21421 agataaaatg cacagctgga ttttcttctg ccaaagtcag agcttctaaa atctcctcac
    21481 acatgggaat atgaaaacca tttgcgacct caggacggtt caaggtaagg attgccaagt
    21541 cctcttcaag ctgataaata atgtgttcca tcagggctcc tttttatttt ataagcagtt
    21601 tatactcttc gaaaatctct ttaaaccgcg tcagcttcca tctgcaacct caaagcagtg
    21661 ctttgagcag tctgcggcta gcttcctagt ttgctctttg attttcattg agtgttaaat
    21721 tatttcactg tcaaagtata tcttttttag gagcagaaag caagaaaaaa tcgactgaaa
    21781 gtgtctcagc cgataagaaa ggctcgcttt aggctagaaa gcatcttatt ttcttcattg
    21841 aaaaaagcct ttctttctgc tataatcgta taaaatactt actttaggag ttcttatgaa
    21901 agttgttaaa tttggaggta gttctcttgc ctctgctagt caattagaaa aagttttaaa
    21961 catcgtcaaa agcgattcag agcgtcgttt tgtagtcgtt tctgcacctg gtaaacgcaa
    22021 tgctgaagat actaaggtta cggatgccct gattaaatac taccgcgact atgttgcggg
    22081 taacgatatt agcaagagcc aaagctggat tatcgaccgc tatgctgcta tggttagtga
    22141 attgggacta aaaccagctg tgctagaaaa aatttctaaa agcattcacg ccttggccac
    22201 tcttcctatt gaagaaaatg aatttctcta cgatactttc ctagcagccg gtgaaaataa
    22261 caatgccaaa ttgattgctg cctactttaa ccaaaatggt atcgatgcac gctatatgca
    22321 ccctagagaa gctgggattg tggtcacaag tgaacctggt cacgctcgca tcattccatc
    22381 aagttatgac aagattgaag aattgacaaa caccaatgaa gtccttgtca ttcctggttt
    22441 ctttggtgtc actaaggaaa atcaaatctg tactttctca cgtggaggtt ctgatattac
    22501 aggttctatc attgctgctg gtgtcaaagc tgacctctat gaaaacttta cggacgttga
    22561 tggtatcttt gcagcccacc ctggtattat ccaccaacca cactcgattc ctgagttgac
    22621 ctaccgtgaa atgcgcgagt tggcctatgc aggcttctca gtccttcatg acgaggctct
    22681 tcttcctgcc taccgtggaa aaattcctct ggttatcaag aataccaaca accctgacca
    22741 tccaggtact cgtatcgttc taaaacacag taatgatgaa tttccagttg tgggaattgc
    22801 tggtgactca ggctttgtca gcattaacat gtcgaaatat ctcatgaacc gtgaggttgg
    22861 atttggccgc aaggttctgc aaatcctgga agaacttaac atcggttggg aacatatgcc
    22921 aacaggtatc gacgaccttt ctatcattct ccgttctcgc gaactaactc ccatcaagga
    22981 agaagaaatc ctgcgtcagt tggttcaaaa gactaaagta gatcatgcag aaatcgaaca
    23041 cgacctttct atcattatga ttgttggtga aaaaatgaag agccacatcg gagtgactgc
    23101 tactgcgaca cgcgctctat ctgaaaacaa aatcaacatc cagatgatgt ctcaaggttc
    23161 tagtgaagtt tctatcatgt ttgttgtcaa taaagaccaa gagaaagcag caattaaagc
    23221 cctctacaat gccttttttg gaaaaagtaa ggaagactaa gcatggccca atcacttaac
    23281 aaaacagtac tcctcagtac gacaggcact tcctacctct ctatcgctgg gaaagttggg
    23341 aaattccttg tcggagatca ggctttggaa ttttacccag atgtcaatgt cgaacaattt
    23401 atccagattc cttggagcca tatcaatcag attggagcca atgtcactgg acgcaaaatc
    23461 agccgccact tcgaagtctt tacagacaaa ggaaaattcc tctttgcttc aaaagactca
    23521 ggtgccattc tcaaaattgc acgcgaaaaa ctcggcaatg acaaggtcgt caaacttccg
    23581 accctgattc agacaattag ccaaaaattt aaaaatctat ttgcaaaaaa gtagaaactt
    23641 tagtataatc atagcaacgg ataagtaggt tatcttcttc tttcagaaag tctgcgggta
    23701 ctgcgagcag ataggaggga taggtgaaat tctaccgtta gtaacaatta catacacaat
    23761 caagtgcaca cctgtgaagt tggatggaac cgtggccctg ccactccaac gttttgtcag
    23821 gcgtgctttt ttcataaagg agttcttatg ttagatatca aacgtattcg tacagatttt
    23881 gaagctgtcg cagaaaaatt agctacacgt ggtgtagatg ctgctgtctt gaatgaaatg
    23941 aaagaaatcg atgctaaacg tcgtaacatc ttggtcaagg ttgaaactct caaagcagaa
    24001 cgtaacacag tttctgctga gattgcccaa gctaagcgca acaaggaaaa tacagatgac
    24061 aagattgctg ccatgcaaaa tctatctgct gaggttaaag ccttggatgc tgaattggca
    24121 gaaatcgatg ctaaattgac agaatttaca acgactcttc caaatatccc agctgacagc
    24181 gttcctgttg gggctgacga agacgacaat gtggaagttc gccgttgggg tactccacgc
    24241 gagtttgact tcgaacctaa agctcactgg gatctcggtg aagaccttgg tatccttgac
    24301 tgggaacgcg gtggtaaggt aacaggcgct cgcttcctct tctataaagg cctcggtgct
    24361 cgtttggaac gtgctatcta caactttatg ttggatgaac atggaaaaga gggctatact
    24421 gaagtcatca caccttacat agtcaaccat gattctatgt ttggtactgg tcagtatcca
    24481 aaatttaagg aagatacttt tgaactcagc gataccaact ttgtcttgat tccaactgct
    24541 gaagttcctc tgacaaacta ctaccgtgat gaaatcttag acggcaaaga tcttccaatc
    24601 tacttcactg ctatgagtcc gtcattccgt tctgaggctg gttctgccgg tcgtgatacg
    24661 cgtggcttga tccgtttgca tcaattccac aaggttgaaa tggtcaaatt tgccaaacca
    24721 gaagaatctt acgaagaatt ggaaaaaatg acagccaacg ctgaaaacat tcttcaaaaa
    24781 ctcaaccttc cataccgtgt cgttgctctc tctactggag atatgggctt ctcagctacg
    24841 aagacttacg acttggaagt gtggattcca gcacaaaaca attaccgtga aatctcaagc
    24901 tgttcaaaca cagaagattt ccaagcccgt cgtgcccaaa tccgttaccg tgatgaagca
    24961 gatggcaagg tgaaactcct tcataccttg aacggttctg gacttgcagt tggacgtaca
    25021 gtggctgcaa ttcttgaaaa ttaccaaaat gaagatggtt ctgtgaccat cccagaagca
    25081 cttcgtccat acatgggtgg agctgaagtc atcaaaccat aaaaaataag gtttagctat
    25141 ttctagctag accttttttc gtaaccaaat cagataagca cctagtacaa agaataaaat
    25201 agttaggcat ataatggttt cagccaatac caggtaatcc agaaatggaa gtttcaaaat
    25261 tccctgagcc atcttgagcg aggtcgctgt gataatggtt gggaaagtga gggctgagaa
    25321 ggctggttga aaaccttgtt ttaaaatgtt gggcagacga gttaaaacaa agaaaaagaa
    25381 ggattgagaa gccaaaatca tgacaatcaa gacccaagtc ggcaggctgg ttcctcctac
    25441 tcgaactaga gaagccaaga gtagagagaa aggagcacag tagattcctt cttgtccaag
    25501 caaggctagt gggagtggat gtttctttaa atcgctataa ataaggggat agagatagaa
    25561 ggtcaagaga aaaccaaaac tcaaggtcgc ataggcaatt tcgataatac ctaccagagg
    25621 ataggtcaag gcagccactg ctatccccac atagagaacc gtccaacttg gagtggcatg
    25681 aaccctccgc cctgaacaag caaacttgat ggtaaaacca gcaatcaagg tcaaatccaa
    25741 gagaaatgaa aaccaccaaa tcccttgtgc taccaaagga agataagaga atacgcgaaa
    25801 gacataggtc gataaaatca tcccagccat aggaaaggtt gccattcctg acaaaagagg
    25861 gggcttggtc aattcttgct tggtttcttt ccaattaaag agatgcagaa ttagaaagta
    25921 aatccataaa accaaaccag tcagactaaa aagatgggat agaaccggca acgtatctaa
    25981 aataagattt ccagctcctg ccaaacctag caaacaacct gaaaatacta aggggagttt
    26041 tttcatccta acctccaata atcatgttag tttcagtata acataaaagc gcttaaatga
    26101 ggatttaaaa aaacgaagtc cgcttatttc agacttcatt ttactcagat atgaattagg
    26161 cataaggttg caattctgga ttaattggtg tattagctaa gttgttggca tagttacaga
    26221 ggattgctag gctgacacca aaaaccacat ccaaggcatt ttgttgagtg tagccagctt
    26281 ctaaaaactc agacaaggct tcatctccta cacgaccctt ggtattgata actgccaagg
    26341 taaacttagc tagggtatcc aatttaggat ctgtttcaat tggagtacga ttgcgaagag
    26401 cttgaatcaa gtcatcattc atctggattt gtttgatgga aaaggctgtg tgacctgcga
    26461 cacagaaggc acaaccattg gtcacggctg ccgtgatttg caccacttca cgctcaacgg
    26521 gtgtcaggct gttgcgacgg tggatagatg agacaatttg gtaggcttct aaaacagtcg
    26581 gggcattggc caagagaccg attaggttgg gaatatagcc attgttgtct ttttctactg
    26641 tttcaagaat ttctttcact tctgctggtg ctgactctac tgtatggata gtaaatgttg
    26701 tcataagata cctcttttct tattattgac actaatatta ttggaaaatc ttataaaatc
    26761 ctgattccta agtttatcta agataaagct ttattctctc ataagatttt cgttgttata
    26821 ttagtttatc acacttccaa tcacttgcat aatatatatt atatatcagg ctgataaaaa
    26881 ttatttatag gcaaaaaaat cacacgagct gtgtgattcc attatttgtc aaaatacttt
    26941 ttagtttcag caataacgac ttgcgacaag accaagaggg caatcaagtt tggcagagcc
    27001 atcaaggcgt taacgatatc tgcgataatc cagaccatat ccaactcgat aaatcctcct
    27061 aacaagacca tgagcacaaa aaccacacgg tagagccaga taaagcgaac cccaaagagg
    27121 aactcaaaac agcgttctcc gtaatagttc caacctagaa tcgttgtaaa ggcaaaaagc
    27181 acaaggaaga tggtcaagag ggcaggccca aagtgtgaaa agactgttga gaaagctgac
    27241 tgagtcaagg caaccccatt caagtcacca ctccaaactc cagttaccaa gatggtcaaa
    27301 ccagttagag tacaaatgat gagggtatca ataaaggttc ctgtcatgga aatcaaacct
    27361 tgctctactg gttcatttgt cttggcagct gcagctgcaa taggagcaga acccagacca
    27421 gattcgtttg aaaacacacc acgcgccaca ccattttgaa tagccatccg aacgctagca
    27481 ccagcaaatc cacctaccgc agcaagggga ctaaaagctg aggtaaagac taaagcgatt
    27541 gtgccaggga tttttccgat attaaagaaa ataactgtaa gagttcctaa gatataaatg
    27601 atggccataa aaggaacaac agtagttgaa accttagaaa tagacttgag tccaccaaag
    27661 actgcaatcg ctacaaagac agacaagacg agagctgtga tggctggcga aatcgtcgtt
    27721 gtattttgga tagattctgt aatcgagttg acttgggtga aggttccgat tcccaagaga
    27781 gcaaccaata ctcctgctac tgcaaacaaa acagcaagtg gtcgccactt ttctcccatc
    27841 cctagaagga tataatgcat gggacctccc gctactgcac catggtcgtc cttggtgcgg
    27901 tatttgatgg ccaagagtcc ttccgcatac ttggtagcca ttccaaagaa agccgccatc
    27961 cacatccaaa atagagctcc tggtccacca accttgatag ccgtcgcaac tcctatgata
    28021 tttcctgttc caacagttga tgccaaggct gtacacagag ctgtaaaact ggatacatca
    28081 ccatgtccct tatcctggat aaaaataagc tgaaaggcct tgggcagacg caaaacctgc
    28141 aagagtccta gccgcatggt taggtaaatc cctgttccga ccaataaaat caagaggggc
    28201 ggtccccaag caaaagcatc gattgattta agcaattcta acatttcctt ctcctatcgt
    28261 ttcaacccca aaagaaagag cacatgcaag atacatgtac tctggaatgc ttagataaat
    28321 gctaaaaagc ggtctatcct agctctgtcc ttttacctga gagtttgagc agttgcctgc
    28381 cttgcccctt cggtgccttt acggtctctc cagagttccg tccatttaca gtcatggaaa
    28441 atcaaacgat tccccacttc tattaaactt cattcggtgt tggtatttaa ttgattctaa
    28501 ttttacaaaa aatgttggct tttgtcaatg tgtttattag taaaaattag ttcaacagtt
    28561 tttactttat aaagtccaga atactgctat cctttaaaag tgacaatagt cgcaccactg
    28621 cctccagcat tttgtggggc atagccgaaa ctcttgacat gtttgtttct ttgcaagtat
    28681 ttggtaactc cttcacggat gactcctgtt ccgataccat ggatgatatc aacttgagcc
    28741 atattgttaa gcaaggcttg gtcgatgaag gtatctagct cattcatggc ttcttcatag
    28801 cgcttgcctc gaagatccag tctagcttga ggtcctcgcc cagaagttcg tttcacaaca
    28861 ttgacctgtt tcttcttgac tggtttttct tgctgggctt gaacaagatc aaactctttc
    28921 tcttccaagg tcatcttaat caagccaact tgggcttccc agcggccgtc cttgagttga
    28981 ctggtcaagg taccacgctg accataactg agaaccacga tatcatctcc cacctttgga
    29041 gctcgttttt tcttggcctt ttgaaggacc ttgtttttag acaagtccac tttttcagga
    29101 gccaattttt tcaacttggc tttggcttca atgatttcgt ggggcttgag ttgggattta
    29161 ctgtggagat ttttgagaat ctggtcactt tcacttaggg ccatatccac aatctcagca
    29221 gcctgttcac gcgccttgtt aagctcggtt tccttttcac gattaagctc gttgtagagt
    29281 ttttttagca cacggttcat cttgagattt tcttgctcca cctcacggat attgtccaag
    29341 cgtttgcggc tttccagcgt ctgctcttct agttgctcaa tgatacgatt gacgtcattg
    29401 tcctgatcga tctgctgact ggcatctcct acgataactt cagataggcc tagacgtttg
    29461 gcaatttcaa aggcattact tcggccagga acaccctgca taaagcgata ggtcgggcga
    29521 agagttgcag tatcaaactc catactggca ttttgcacaa aggctgtctc aataccgtag
    29581 gccttgagtt ctggatagtg ggtcgtcgcc atggtcttga tttgacgcag gcgaaggtcc
    29641 tccagaatag ccatggcaag ggctgctccc tcttggggat cagtaccagc ccccaactca
    29701 tccaaaagta agagtgaatg ttggttgacc ttgccaagaa tatccacgat attggtcata
    29761 tggctagaga aggtagacaa gctctgctca atagactgct catctccaat atcagcaaag
    29821 atttcttcaa aaataccaac acgacttccc ttgtctgcta aaatcggcaa tcctgactgg
    29881 gccatgacct gtgtcaagcc cagagttttg agcatgatgg tcttcccacc tgtattggga
    29941 cctgtaatga caatagctgt taaatcttga ccaaaataga catcatttgc gacggcattt
    30001 ttgaccaaag gatggcagac atggagcagt tgaatctctt gattttctga cagctgaggc
    30061 acgactgctt gtctttcttg gataaatcga accttggcac gaatcaagtc cagatgaccg
    30121 ataatccaag cgtcattagc aatctcagcc gcatgagggc ggacacgctc agaaatttct
    30181 tggagaatgc gaagcatttc atagcgctca tctgctcgca gactagcaat ttcttcgctc
    30241 agtttgacta cctcacgtgg ttcgatatag acggtgtttc cactagcaga aatatcatga
    30301 acgacacctg caatcttatt gcggtaggtg tttttgactg gtaaaacctg acggccattt
    30361 ctgctagcaa caattccttc cgtcaacatc tgcgcttttt gcttgagcaa gtcttgtaaa
    30421 acatcgcgta cctgactctc gctatcatgt atttttcgac ggattcgcgc caattcttca
    30481 ctggcaaaat tttcaatgaa acccgcatca ttaaaggcct gaagatttcc ttgtaattgc
    30541 ggaaaatcat gtaatttctc aaaccaaagg gctaattctt ccaagctgac attttccaga
    30601 ttggcgtaaa aactttgaag ttctcggctg gtaagaagca cgcgtttcaa gagtaggaac
    30661 tcctcgatat tgagatccgc tcccatctcc aacctcttgc agactcctgc aatttcctta
    30721 gttgagagaa tagtaaaatg cggttgctcg acgaaaagag cctgcatttc tttcatctca
    30781 gcaaaagcct gtttgatttt atctgctttg gcagtcggag ccagctgtct caattgctcc
    30841 aagccctgct cggtcaacaa atgaggctca aacaaggcct tgaccttatc gaactctaat
    30901 gtttctaata ttttcttatt catctttatt tccttgtctt tgaatgtcta ggtgtggtag
    30961 ctttttacat tctgatagat tcgagtcaaa tctgtaaaca aagggctagg aaaactcctg
    31021 ccctttttat ccgattaaat ttgtcaccca gatttgtttg agccaactgg ttgttatcgg
    31081 tatgctctgg atgatgtgtt ttgcgacgat actcttttca agaggatttt gtataactgc
    31141 catggggatg gtcgccaaga ttgtcaaggc catttgcaag acaaataagg tcaccaacat
    31201 ggacaagata cctgctgaaa cttggaacaa cttaccaccc agttttttgc taggaatcaa
    31261 gtgtaagaga agaccaagca aacgaccaat gctatagaca atcccaaata caagcaagta
    31321 gccgatacct gcataaaaga ccttatccag ctgaaagagt tgatccgatg ggaaaaagaa
    31381 agtcccctga ccttcctgcg aatttgcata agggagcaat aaatggaatt gctctccaag
    31441 ccccttataa aactggccag ccataaaagc cgatgccatg gctgaaatca ggtaataaac
    31501 ctgtaagagc aggcctctcc gatagccgat ataaaatccc caaaccaaga ccaatagaag
    31561 aaggaatgaa atcataagga atcctcaatc ttgctctgtt cttgcttaca agtcacaagc
    31621 ttgtgacgga gttcttctag ctcttgctcc ttatcgtcaa attcaatctc acggctgagc
    31681 tgagttgata aacagttgac tgccaacaaa agagcgattg tttcatcatc tgcgctaggc
    31741 atttgttctt taattgcttg gtatttttct gtcgcaacct tagcgatttc ctccataaaa
    31801 aggttatcat gttcgcttgt caaggttaac gattttttcc cgaatgtaaa tttgaatcga
    31861 tttagatttg ccataaaatt cacctcacga tattatacca aaattcgcta attttgtcag
    31921 tttttacaaa ttttactgct tttgtggtac aatagaaact atggcaagta tcacactcac
    31981 accaagcgaa aaggatattc aggcttttct tgaacactat caaaccagtc tggctcctag
    32041 caagaatccc tatatccgct actttttgaa actacctcaa gcaacggttt ctatctatac
    32101 ttctggaaaa atcttgcttc agggtgaagg ggctgaaaaa tacgccagtt tctttggcta
    32161 tcaagctgta gagcaaacca gcggacaaaa tcttccttta attgggacag atgaggtggg
    32221 aaatggttcc tactttggtg gacttgcagt tgtggctgcc tttgtcacac ctgaccagca
    32281 cgacttttta cgaaaactcg gtgtggggga ttctaagact ctgaccgacc aaaagatccg
    32341 tcagattgct cctattctca aggaaaaaat tcagcaccag gcactccttc tctcacccag
    32401 caagtacaac gaggtcatcg gagaccgcta caatgctgtt tcggttaagg ttgccctcca
    32461 taatcaggct atctatctcc tccttcaaaa aggtgttcag cctgagaaaa ttgtgattga
    32521 tgcctttacc agtgctaaaa attatgacaa gtacttggca caagaggcca atcgtttcag
    32581 caatcctatc agcttagaag aaaaggctga gggcaaatac ttgtctgtcg cagtttcttc
    32641 tgtcattgcg cgtgatctct ttctggaaaa tcttgaaaat ctgggacgag aactgggtta
    32701 tcagcttcca agtggagctg gaacggcttc tgacaaggtg gctagccaga ttttgcaagc
    32761 ctatggtatg cagggactca acttctgcgc caaattgcac tttaaaaaca ctgaaaaagc
    32821 gaaaaaacgc ttagaaaggt aagttatgaa ttcatttaaa aatttcttaa aagagtgggg
    32881 actgttcctc ctaattctgt cattactagc tttaagtcgt atcttttttt ggagcaatgt
    32941 tcgcgtagaa ggacattcca tggatccgac cctagcggat ggcgaaattc tcttcgttgt
    33001 aaaacacctt cctattgacc gttttgatat cgtggtggcc catgaggaag atggcaataa
    33061 ggacatcgtc aagcgcgtga ttggaatgcc tggcgacacc attcgttacg aaaatgataa
    33121 actctacatc aatgacaaag aaacggacga gccttatcta gcagactata tcaaacgctt
    33181 caaggatgac aaactccaaa gcacttactc aggcaagggc tttgaaggaa ataaaggaac
    33241 tttctttaga agtatcgctc aaaaagccca agccttcaca gttgatgtca actacaacac
    33301 caactttagc tttactgttc cagaaggaga ataccttctc ctcggagatg accgcttggt
    33361 ttcgagcgac agccgccacg taggtacctt caaagcaaaa gatatcacag gggaagctaa
    33421 attccgcttc tggccaatca cccgtatcgg aacattttaa gaaacctaag aggccgagaa
    33481 tcaccaatct cagcctcttc ttctatcgtg agaaaatgat tggtactatc taaacttacc
    33541 agaacagaaa cacctcaact ctcacctatt catgcaaagg aattttatgg aagtttattt
    33601 ttcaggaact attgaacgga ttatttttga aaatcccagc aatttttatc gcatcctcct
    33661 cctagaaatc gacgatacgg acgcagagga ttttgatgat tttgaaatca ttgtcacagg
    33721 aaccatggct gatgtaattg agggcgaaga ctatactttt tgggggcaaa ttgtccagca
    33781 ctccaagtat ggagaacaac tgcaaatcag tcgttatgat cgcgcaaaac caactagtaa
    33841 gggcttggtc aagtactttt caagtagcca tttcaagggg attggtctca agacagctca
    33901 gaaaatcgtg gatacctatg gcgaaaatac cattgacgaa attttgcaac acccagaaaa
    33961 gttagaaggc atcgcaggac tctctgccaa aaatcgcgag gctttcgtct ccactctccg
    34021 tctcaactac ggaacggaga tgattttggc caaactagcc aactacggca ttcccaacaa
    34081 actagccttt cagattcaag acttttacaa ggaagaaacc cttgatgtgg ttgaaaatta
    34141 tccctaccaa ctggttgagg atatcaaggg tttgggcttt accattgctg accaactagc
    34201 tgaggaacta ggcatcgaaa gtcaggctcc tgaacgcttc cgcgccggtc tagttcacag
    34261 tctttttcag acctgtatgg aaacagggga cacctatgtt gaagcacggg atttgctgga
    34321 acaaaccctt actctccttg agtcttcccg tcccgtggaa ctagacccca gccaagttgc
    34381 ccaagagctc tcctacctga tcgaagaaga caaggttcag cagattgata ccaagatctt
    34441 tgacaacagc ctctttttcg ctgaggaagg tatccgcagt cacttgattc gtatccttga
    34501 aaaaggaaaa cagaagagcc aagatttaga aactattcaa aagcatatca ctactgtcga
    34561 gcaagaactg gggattgagt atgataacat tcaaaaacaa gctatttgtg acgctatcca
    34621 gaacaaggtc tttatcctga caggtgggcc tggtactggt aagacaactg ttatcaatgg
    34681 aatcatcgct gtttatgccc ttttagaagg acttgacttc aggaagaaaa acaatctgcc
    34741 cattcttctt gctgctccaa ctggtcgagc tgctcgtcgc atgaatgaat tgacaggttt
    34801 gcctagcgcg accatacatc gccacttggg aatgacaggt gacgatgata ccagtcatct
    34861 ggaagattac ctagatgctg actttatcat cgtggatgaa ttctctatgg tggatacttg
    34921 gctggccaat caactcttct ccaatatctc ttctaacagt aagatcctca tcgtaggtga
    34981 cagtgatcag ctaccttctg tcagtcctgg acaggttcta gcggatctgc ttcatattcc
    35041 tttgattcct cagactcgct tggaaaaaat ttatcgacaa agcaaagaat caaccatcgt
    35101 caccctagct agtcagattc gacagggcat cttgccagct gatttcaccc aaaaaaaagc
    35161 tgaccgttcc tactttgaaa ttgctagtgg ccatattcct gccaccattg aaaaaatctt
    35221 aggtgccgcc ctcagaaatg gtattcctgc ccgtgatatc caagttctgg ctcctatgta
    35281 ccgagggacg gcagggattg atgctatcaa tcagctcatg caagacctgc tcaatccccc
    35341 acaaaaagat caactcagtt ttgaagctcc tcagtgccac tatcgtaaga gagacaaggt
    35401 cattcatttg gttaacgatg ctgaaatcaa tgtctttaat ggggatttag gagctatcac
    35461 agacctgatt cctggtaaat acaccgaatc gaaacaagac gagattgtca ttgattttga
    35521 tggtaatgaa gtctcttacc cccgtaacga atggtacaag attcgcttgg cctatgccat
    35581 gagtattcat aagtctcagg gaagtgagtt cccagttgtc atcctaccga ttactagtgc
    35641 tagccgacgt atgctggagc gaaatctcat ctacacagcc attacacgtg ccaaaagcaa
    35701 actcatctta ctaggcgaat tacaagcctt cgactatgct acccaacaca tcggaactgc
    35761 ccgaaaaacc tatctgattg aacgcttcag tgatctactg gagaatgttg aagaaaagca
    35821 acaagctgtc tctgaaacag tcacatcaag tgcctctgaa caatcctaca tcctaaccga
    35881 agaaaactgg gaccgcatcc cagccatgat tgggattaca gacacagacc tcaaagagat
    35941 ttttggaaaa tagtgcatca gaaaacccac caattcaggt gggttttctg tttattaaga
    36001 ttattttact gttgctgtgc ttgtaatcaa ttcaacagct tttttgattg tgatatcatg
    36061 tttcaacatg tcagctgaaa gcaagctttg tacttgagca acttccatgt tgtagtctgc
    36121 tgccaattgc tcaacttctt tttggatttc ttcttctgaa gcatcaaatc cttcagcttt
    36181 ggcaactgct tcgataacaa ggttagtctt agtacgtgac tcagcttctg cttggtattg
    36241 gttgtgaagg tcttcttgag tagttccagt gatttggaag tacatgtcag ggttgatccc
    36301 ttgacgttgc aagttcccaa ggaattcatt tactgaacgg tgaacttctt cgtggatcat
    36361 ttcttctgga agttctacga tttcagcatt ttctacagct gtatcaattg ctgcaccttc
    36421 aactgcatct ttgtaagctt cttctttagc agcagccaat tctttgcggt atttttcttt
    36481 caagtcagca agtgtttcaa cttcttcatc aatgtctttt gcaagttcat cgtcaagagc
    36541 tggaacttct ttagctttta cttcatggat agttgtcacg aatttagctt ctttacctgc
    36601 aaggtcttct gcttggtagt cttctgggaa tgttacgata acatcaacgg tttcgccagc
    36661 tgagtgacct accaattggt cttcgaaacc agggatgaat tgacctgaac caagtccaag
    36721 tgagaagttt tcaccttttc cgccgtcaaa ttcaacaccg tcgatagaac caacgaagtc
    36781 gatcacaaca gtgtcgccgt cttcagcagc agcttccttg ataaccaatt cagccaggtt
    36841 gttgcgttcg cgttcgatac gctcttcgac atcagcgtca gttacttctt tttctacatc
    36901 aactgatact tcaaggtttt tgtagtcacc caattttact tcaggttttg taacaacttc
    36961 agcagcgata acccagtctt gacctttttc cattgaagtt acgtcaattt ttggttgggc
    37021 aaccacttca agaccagctt cttttacagc tgcttcataa gcgtttggca aaagagcgtt
    37081 cataacgtct tggtaaagtg attcttcacc aaatttttta tcgaagatag gacgtggaag
    37141 gtgaccttta cggaaacctg gaacattaag agatttcttc actgacttga agacacggtc
    37201 caattctggt ttgatttggt cttgagagat agtgaaagtc aagacaccac ggtttgtttc
    37261 tttgttttca aatgatacag acattctgtc atttctcctt aaaatttttt aaatacagtc
    37321 tattataaca ttttctataa ataaaatcta gactaatgca gacaattata gacaacaagc
    37381 ctttttccta actaaaacac tcataaagta tagacaattt tagactactt tggatatctt
    37441 ttggttagtc attttccaaa actaatttat ctaattttta agttatattt gacttcatct
    37501 tctcagtaac atgagtataa acacttaaaa tctttgtttc attagtataa tctacacgat
    37561 ccattatcgc tattataggt acttccaatt cagcaagcaa acttatatgc gaatatctaa
    37621 aaacatgagc agtcaataca aaatcatctt tcttaatttc acttttccta aacctgtttt
    37681 tcaaaaagta attgaaacaa gttatcatta agggagaacc attatttgta aatatataat
    37741 caccttcttc taaaagaaga tattctttta aaatttctaa cactctatca ctaataccaa
    37801 ttactctata tgaagctaaa cttttcggac tatccaaaaa cacttcgtta ttggacgatt
    37861 acattatagt aaaacgaaat aagaacagga caaatcgatc aggacagtca aatcaatttc
    37921 taacaatgtt ttagaagtag atgtgtacta ttatagtttc aatctactat acaagacgaa
    37981 attgaagaaa tctttccatt ataaaacgca tattatcaag gtttttaaac acctaataat
    38041 atgcgttttt tcctatttta aagactttta tccacctatt atacaaagtt aagtatccat
    38101 cacagtttac aattagccgt cattacctaa cccattcacc atccttcaag agagtaacct
    38161 ttaagaaccg aataaataaa tggcaaattt cgttcattta atttaactgc actgttaatt
    38221 tgattagctc catctcctaa agtatgcact cctactacgc ggttactagc atcataaact
    38281 gtagatccac tagacccctc taaagtatca acttggtagt ccaagaacat gccatcatca
    38341 cttaaaactt gttttttatc tgtatacatt tgatgaattt taaaattata tgatggatag
    38401 cctgtgatag tcacagttat tcctgtcaaa tttttttgac tagtaggaag acccaaagtc
    38461 cctaattttg caccaatggg ctcttctaga attaataaag ccaagtcata ttcccttgca
    38521 tccttagaat ttaaatttct aaattccttc aaataacgaa cttcttttac ttttatccga
    38581 ccaaacggca cactatttgg agtacgagca ggagtaacat atagttcttc tgcatcttta
    38641 ccaaactcat gtttataaat attatgagca gcagtaataa ggacattatc ctttataaaa
    38701 ttggcactcc ctcgataagt tacatcttta ccatttttca caccacgaaa ttctgactct
    38761 acataagctg atgtagaata aggatattgt aaagtatttt ttaccttaac taaatcattt
    38821 ttaccaataa tgacttctga ctgatttgta taatattgac cataagtcgg tgaaacattg
    38881 ggaagtgaaa aattattagt tcctggacta tcttgtaatg tctcacttac ctcatattct
    38941 tcacctgtac tagaaataac actcaaagca gatactgtcg ataactggct agccaataaa
    39001 gtactcgcaa taattgaaat acccaatttt ttataaacag ttttcttcat tattgtatcc
    39061 tcctaatgta attatagcgt actattctaa atttcttaat ctactataga atcaagaaat
    39121 ctaccacctt ctttaaatac cctccattat cacataaaca ggtaaacttt tcaattaatg
    39181 actgcgcttt tcaatcacgc tagaggtact tgcttgcttc tttgatacta agttcagcca
    39241 ttctttcctt gtttttctca ataaagcatg ttacccaagt gggattcgtt ttggagtagt
    39301 ctcgcagagt ccagccaatg gctttattga taaaaaattc tgtttggttc aagttatgaa
    39361 gtagaatctt ttccattaat tgagtattgg tcttctcttt tcttaacaac tggtggtcaa
    39421 tagcgacacg tctcagccag atattatctg ataggctcca ttttatactc aatgaaaatc
    39481 aaagagcaaa ctaggaagct agccgcagat tgctcaaaac actgttttga ggttgcagat
    39541 agagctgacg tggtttgaag agattttcga agagtattaa gattatttct tctagttcag
    39601 agtgttcata caccaaactc cctactactc gatctaggat atctaccgtg tcccaccagg
    39661 attttgtcac gactaactgc tctagcttag gcaaatcggt ttcctttaga taagactgca
    39721 ttgctttcaa atagttagca gccacatatt ggtattctct aggatccttt tcccagcaag
    39781 tgtctgcaaa atcccaatcg ataatctttg tttttttcgc ttctggaaaa tatttttata
    39841 gagtttattt ctttcaggca ccgcaatacc tagaaaagaa aattgatggc gcatataggc
    39901 ttccatggac cttgcttttt tagagtcttt tgctgcttct agctcctcaa gtaaatctgc
    39961 taaactcatc taaaactcct cttgccccac caaatggtgc tgaaaggcat agacagtcgc
    40021 ctgggtacga tcgctgactt caagtttggc aagaatattg gacacgtggg tcttgaccgt
    40081 cttgagagag ataaagaggt catctgcgat gcgctgattt tcgtagccct tggcgatgag
    40141 ttggagaaca tctcgctcac gcgcagtcaa ttcttcatga agttccatat gattgcggtg
    40201 gtattcaacc ttcttgctaa cctcttgctc aatggccagc tcgccagcag ctaccttact
    40261 gacggcatga agcaattcat ctgcactaga agtcttgagc atatagcctt tggcaccagc
    40321 atctaagact ggcatgattt tttcattgtc caaataagag gtcacaatca aaatcttggc
    40381 ttcaggccat tctttaagga ttgctaaggt cgcgtcaatc ccattcatct caggcatgac
    40441 aatatccatg acaatgacat ctggacgcag ttccaaggcc aagtcaatcc cttgagaccc
    40501 gttggacgcc tcacccacaa cttctacatc gtcttggagg tcaaagtagc ttttcaagcc
    40561 caatcggacc atttcatggt catctactag taaaattttc atctttactc ctttatcatt
    40621 ccttatctaa caggggaata cggatatcaa ctgccagccc ttgcttggga gctgttaata
    40681 actgaaccgt ccctgccata tcttcaaccc gctccttgat atttcgcagt ccataactca
    40741 agtcgtctaa gctccctaac cggaaaccaa tcccattgtc caccaccttc agttgcaatt
    40801 caacatctgt ctgatagagg tagacatcta ggcaagatgc ctgggcatgg cggagcgtat
    40861 tgctaatcaa ctcttgcagg atacggaaga tatgctcctc gattttctta ggcaatttcg
    40921 tcatattctg cttgagacta accctaagat cactcttgtc ctcaagctct tttaagagaa
    40981 tctgaatccc ttctatcaag ctcttctgct ccagttcaac tggtcgcaaa tgcaagagca
    41041 aaacccgcaa atccttctgg gcagtttcta aaatagctgt gacactctgc aactggatct
    41101 gcatcttttc tctatccaat ttcaaagcct gctgactgat acccgataaa atcatgtggg
    41161 ccgcaaacaa ctcctgactg actgtatcgt gcaaatcccg agcaattcgc ttccgttctt
    41221 tctcgatgat ttcctcttcc tgagcaaggc tatgattttc agctttttga agagcttctg
    41281 tcaaaaggtt aagtttacct gataaggact tgaaactggc atccaaatct ggatctgcaa
    41341 cctgaaccac ttcttgccct gccaataaac gcttgagatt agcctgcatt tttcttagag
    41401 aaagctcttc gatccctcgc caaaacaggg ctaagagaca ggttatggac atgctgaaaa
    41461 ccaacaataa aaagacaaat ttttctgttt tttcgacatc gtgcaaaaag atagaccagt
    41521 caaaatcaag tatttccagc aagctgtggg agaaaaaaaa gacaaatagg aaggaggtga
    41581 gagcaataat gacataggct tgttttttca tcctctaacc acctccacat caccaatcat
    41641 agtggtcaag aaaatcttga cactcttgtt actcttgaga tagtcttttg tttcttgatg
    41701 atagtgttca ttgcggaggg ctcgcttggg ctggttgaaa aaagtcaaat ccccatagag
    41761 acagttaacg ctgagactga cttccacatc tacaggtacg atgattttgg tcgttcctac
    41821 catctttctg aggataatga cattgtcatg attggttaag atgaccctct ccagatgaat
    41881 agtgtccttg cccatgaagc gaaagagatt gatatcatcg aattggcaag tctggtagct
    41941 tgaaaaatga tgaagatttc caaaccaacg atttttctcc ttcttaaccg tcacgacctc
    42001 ttcaaaaacc aaattggtct gctctttttc ctggttcatc atcgggtaaa gaagaaagag
    42061 gctatagata accgcaacaa aaatagctag aatcacaaaa ggattgagca taacgatgaa
    42121 aaagaagaga atggttgccg ctactaaaag aagattattt ccctctttac cagtgtagta
    42181 gcgaatcaaa agcaaaaaga ggaatagtat cagcagaaaa cgcgaaaaat gctctgatac
    42241 catcaaaatc agagctcctg tcagaagaca ggcttcgata aataaaaaga ttttaaattt
    42301 tctcataggt tcatcctctc ccttctattt tatcacaatt caaaaaagtc acctcagtct
    42361 gaggatggaa aaaaaggcgc tggttacgcc tttttcatct gatcctttgc ttcttttaat
    42421 tttccataaa gaagataatc tactttttgt agatctgcta tggtggcaca gttaagggaa
    42481 cacataatca agcgtagatc tgctttccag ccttggacaa tgccaatcac ttcttcaact
    42541 gtgtaggttt caaccaattc cagaacggtt cgtgacaatc ccacagcctt agcaccaaaa
    42601 accaagcact taatcatatc cagcggattc cgaacccctc cactaaccaa gagttcgacc
    42661 ttatctttcc attcttgggc attgagaagg gcctgcatgg tagactgacc ccattgattg
    42721 aggtaatcac gctggccact acgacggttt tcgatatagg caaagctggt gccaccacga
    42781 cccgataggt ccactgtacg aacaccgaat tcataggctc tttcgattgt cttggcatcc
    42841 attccaaagc ccacttcctt gaggacaata ggaacgggaa tttgcttgat ataatctgct
    42901 aaatgcgatt gccagcttct aaacttcctt tctccctcgg gcatgagtaa ttcctgcatg
    42961 acattgacat gcacttgcaa tagaacagga ttcatctctt ctacagtctg aagtcctaac
    43021 tcgacaggct tgtccaatcc aatattggtt ccaaggagga gattgggatg actagacttg
    43081 acagaaaaag aatcatccgt tggatttttg agggctgcgc tataagaacc cgttacaaat
    43141 aaaataccac aggattccgc cacctgagcc agcttttgat tgatttctct tcccttatta
    43201 cttccaccag tcatggcatt gatataaaaa ggaaagtccc actttcgacc agcaaactct
    43261 gtcgaaagat cgatttcatc cagattgtaa agaggcaagg aagaatgaat cagctccacc
    43321 tcatcaaagc tattatagga acttttctgc tcaagggcat agaggatatg ctcgtcctta
    43381 cgatttgtcg tcatgtccta tcctttcttg atataagagc tcaatcccca gatcggccca
    43441 acgatttttt aaggtttcgg ttgattgcgc atcaaaactc agggcgatgc cacagtcacc
    43501 accaccagca ccactactct tggcaacggc ctgcaaatct tgactggctt ctttcaactg
    43561 tctaagcaaa ggcgtgtaaa tatctgtact caagccttct aaaagcttgc tggctacttc
    43621 tacttgctcg ataacttttt cggctttccc ctgctccaag gcttcgacca aagaaaccac
    43681 cgtttctttt gaggaactta aaaaattttg attgatattt tgcttgattt gctggaccat
    43741 gtgactcgat acagccactt ccttggtcca tcccactaag aaatcacatt ctaaagttgg
    43801 tttcacttgt gagataaaaa atccccaatc acgctccaga actgtcgcca agttttcttc
    43861 ttctaaccaa gcagccgcct tctggcgatc aaatgactgg tagagaacca aatcctctgc
    43921 cacaatacag gcaaggtcgc ccatggaacc attgtctcct cgcttgagca agacagcgct
    43981 agtcagcttg aacaagagat tctgatcaac cgaaagatta tagagagcca gtaaagcctt
    44041 gacaaccaag acaacgacgc tgccactaga acctagacca aactttttcc cttctcgttc
    44101 cattttgcca cagattttta gggaaaaagg tcttaaattc tgaccgcgaa cagcgaggaa
    44161 gtctcccatc aaagcaatcg tttcttgaat caagctgtag tcaggattgg gccttaagtc
    44221 cactgcgaaa tcaaacatat ctgaatagat acggtagctg tcagaaaaag caatctcagc
    44281 cctcatatag atgggaatat cctttatcaa agctaactgc cctggctcta aaatagcata
    44341 ttcacctgcc caatagagtt ttccgcaagt tttaacagca atcatcttga ctcaaatcct
    44401 ttgtttttga cacaatcaag cgataacgct gaccgaaaat ttctgacaaa tgctccaagt
    44461 ctttctcctg acagaagacc ttaacattgg gaccagcatc catggtaaag tagcaggcct
    44521 ctcctttctc acgaagctgg cgaacaaagg ccatagcctc ataagaggca tccgtcagat
    44581 aagaaaaggc tggactagca gtctttgtcg tagcatgcat agccagagca tttttctccg
    44641 ttaattctcc aatcttggca aaatcatttt ccttgagata aatcagcata tcctgatagt
    44701 ccttctcaga ctgacgaacc cagtcgtcaa aagtcgtcga ggtttccaca caaagtttca
    44761 tcccgtcacg gctagagatt ggttttttct tgtcctctag caccaacata atcatagcta
    44821 gtttcaagtc tgtctctaca gggtaaattt ctccactatc cttatcccag gctcctagtg
    44881 gtccataaaa actccgagaa gaagagcctg aggcaaattt ggcttcctgt gccaactgac
    44941 ttctatccaa tccaagcttg aaataagcat tacaagcctt gaccagggcg gacaaaccac
    45001 tagaacttga ggacaggccc gctgccgtag gcatattgtt ttgagtatcg atacggacaa
    45061 agccctcacc agctggacga taacggtcaa taatcttact catcttggca tgctcgacct
    45121 cattttgtag ctgaccattg atgtaaaatt cgtcagctgt tacattggct ggtaaaggcg
    45181 acaaggtcgt ctctgtatac atattttcca aagttagaga aatactgcta gtagcaggca
    45241 ccatctcttt ttcttttttc tttccccaat atttgataat agcaatattt gcgtaggaac
    45301 gtactgttac aggctctcta tccatgtctg aacagctcct ttctcttcta atctttctgc
    45361 tagttcttgt gcgtgcgtca aattggttac caaggctatg atacaacctc ctagcccacc
    45421 accgctcatc ttggcaccca gagcaccata gctaagagcc gtttcaacca aaaagtctgc
    45481 ctcagggcta ctgactccaa tttcttttag atgtaaatgc gcttgactga ggatttgtcc
    45541 cagtccttca gcatcttttt gtgaaatcgc aacttctgct tgctgggtta attctcccaa
    45601 ggcatgcaaa aacggtaggg catccttgcc cttattttga accacttgga tggcttcacg
    45661 agtatgacca taaacacccg tatcggcaat caccaaatag gcggataaat ccatctcaag
    45721 ttctgtaaat cctacgttct tgataaagcg aataggttgg tcactgagac aggtcttagc
    45781 atccaaacca ctaggattca tatgggcaat catctcagct cgattgacca agatttctag
    45841 tacatcatga ggcagatcag cctgatagta gtcaaatacc gcacgaatgg ccgctatgct
    45901 gatagccgct gacgaaccca tcccccgttt ctcagggata gccgagtcaa tctcacaacg
    45961 aacgcaggct tctgtgatat ccaaatactc cagtgaggca taaaccgcca tggacaaggt
    46021 atcctcctca taaaggcgcc aaggactctc tgcagaaact accttacagg tcacctccac
    46081 ctccaaaaga ggcagggaaa tggcaggata accgtaaacg accgcatgtt cccctattaa
    46141 aattatctta ctatgtgcct gaccgacacc aacttttttt gtcatttttt ccttttacta
    46201 gacgaaaaaa cgtcttattt ttcatacaag tattaattct ttcctatcta ttttattata
    46261 ttttcacaaa aaaagcgatt gtttccattc acaatcgctt ctttcattat tgaacccatt
    46321 cgccattata attgacaaaa tagccatcta cggtcgtatt cactgccaag gcacctgagc
    46381 tataagcgta gtaccatctg ccattgacct ggaaccaacc tgtcgtcata gaacgacgaa
    46441 agaaactcca taccattaag taaagaggaa agtcgtgagg gagcatgcgc cattgacaac
    46501 ctgttttagt gacgtacaaa gtctcattaa caagtactcg tttcggccat ttataggtgc
    46561 ggtgtttgga gaaatagggt tcaatcttag cccattcttg atcgtttaaa tcagtatcat
    46621 atactttgcg tgtcataact ctagtttaac attttttgtg aatacaggtt ctaaataatc
    46681 gaccacgaaa atttcttaag tggaaaacgc cttatgaagt atgctacggg aaagttatgc
    46741 acttaatttg acaattcaag atgtaaaaat atatactata gtagattgaa actagaatag
    46801 tacacc
//
LOCUS       DAVKMO010000011        40258 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVKMO010000011 DAVKMO010000000
VERSION     DAVKMO010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40258
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.011"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(108..668)
                     /locus_tag="VW361_000705"
     CDS             complement(108..668)
                     /locus_tag="VW361_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743799.1"
                     /translation="MALFIAVVNNNITSLPSIALSLERENVDFLKSLPFDFARYVKVK
                     FWIIFAVQSFLPVLTLLGLSLYLGLPILSMIYLIVAWILASVILSCHHYFKDVKNLST
                     NWSSITDLVNRSNGIVAIVLLFILLFIYSAILMALVIGSIFLVQSLSPILAISLGVGA
                     LILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(640..1752)
                     /locus_tag="VW361_000706"
     CDS             complement(640..1752)
                     /locus_tag="VW361_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743800.1"
                     /translation="MRLKVIKKLVDINILYSSKEANLANLRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFVVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPFFYSSLYSSCQ"
     gene            complement(1733..2482)
                     /locus_tag="VW361_000707"
     CDS             complement(1733..2482)
                     /locus_tag="VW361_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743801.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSSSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            2662..4116
                     /locus_tag="VW361_000708"
     CDS             2662..4116
                     /locus_tag="VW361_000708"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU9743802.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAEDAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHMEAFQVIEVDPVDRTVKLGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKSVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(4206..6824)
                     /gene="alaS"
                     /locus_tag="VW361_000709"
     CDS             complement(4206..6824)
                     /gene="alaS"
                     /locus_tag="VW361_000709"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU9743803.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESAFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELALIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(6846..7331)
                     /locus_tag="VW361_000710"
     CDS             complement(6846..7331)
                     /locus_tag="VW361_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU9743804.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEILESQS
                     H"
     gene            complement(7606..7845)
                     /locus_tag="VW361_000711"
     CDS             complement(7606..7845)
                     /locus_tag="VW361_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743805.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(8098..9168)
                     /locus_tag="VW361_000712"
     CDS             complement(8098..9168)
                     /locus_tag="VW361_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9743806.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKELQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKKLLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(9165..9938)
                     /locus_tag="VW361_000713"
     CDS             complement(9165..9938)
                     /locus_tag="VW361_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9743807.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(9935..10741)
                     /locus_tag="VW361_000714"
     CDS             complement(9935..10741)
                     /locus_tag="VW361_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9743808.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(10722..11879)
                     /locus_tag="VW361_000715"
     CDS             complement(10722..11879)
                     /locus_tag="VW361_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743809.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(11938..12888)
                     /gene="murB"
                     /locus_tag="VW361_000716"
     CDS             complement(11938..12888)
                     /gene="murB"
                     /locus_tag="VW361_000716"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU9743810.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(13000..13757)
                     /locus_tag="VW361_000717"
                     /pseudo
     CDS             complement(13000..13757)
                     /locus_tag="VW361_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(13767..14498)
                     /gene="budA"
                     /locus_tag="VW361_000718"
     CDS             complement(13767..14498)
                     /gene="budA"
                     /locus_tag="VW361_000718"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU9743811.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            14640..15911
                     /locus_tag="VW361_000719"
     CDS             14640..15911
                     /locus_tag="VW361_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU9743812.1"
                     /translation="MKKQSKYKEVVSYLKNGIESERFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKLSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(15931..16746)
                     /locus_tag="VW361_000720"
     CDS             complement(15931..16746)
                     /locus_tag="VW361_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9743813.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKDQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTNLKSANIAAQKGT
                     VPESMVKEQLPKVQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(16903..17556)
                     /gene="phoU"
                     /locus_tag="VW361_000721"
     CDS             complement(16903..17556)
                     /gene="phoU"
                     /locus_tag="VW361_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9743814.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(17568..18326)
                     /gene="pstB"
                     /locus_tag="VW361_000722"
     CDS             complement(17568..18326)
                     /gene="pstB"
                     /locus_tag="VW361_000722"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9743815.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(18339..19142)
                     /gene="pstB"
                     /locus_tag="VW361_000723"
     CDS             complement(18339..19142)
                     /gene="pstB"
                     /locus_tag="VW361_000723"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9743816.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLSQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(19153..20037)
                     /gene="pstA"
                     /locus_tag="VW361_000724"
     CDS             complement(19153..20037)
                     /gene="pstA"
                     /locus_tag="VW361_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9743817.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(20027..20944)
                     /gene="pstC"
                     /locus_tag="VW361_000725"
     CDS             complement(20027..20944)
                     /gene="pstC"
                     /locus_tag="VW361_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9743818.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(20944..21822)
                     /gene="pstS"
                     /locus_tag="VW361_000726"
     CDS             complement(20944..21822)
                     /gene="pstS"
                     /locus_tag="VW361_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU9743819.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(22396..23700)
                     /locus_tag="VW361_000727"
     CDS             complement(22396..23700)
                     /locus_tag="VW361_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU9743820.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKKPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLQETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(23701..24474)
                     /locus_tag="VW361_000728"
     CDS             complement(23701..24474)
                     /locus_tag="VW361_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU9743821.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(24464..24742)
                     /locus_tag="VW361_000729"
     CDS             complement(24464..24742)
                     /locus_tag="VW361_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU9743822.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(24742..25143)
                     /locus_tag="VW361_000730"
     CDS             complement(24742..25143)
                     /locus_tag="VW361_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU9743823.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(25353..25970)
                     /locus_tag="VW361_000731"
     CDS             complement(25353..25970)
                     /locus_tag="VW361_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU9743824.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(25960..26733)
                     /locus_tag="VW361_000732"
     CDS             complement(25960..26733)
                     /locus_tag="VW361_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU9743825.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(26744..27481)
                     /locus_tag="VW361_000733"
     CDS             complement(26744..27481)
                     /locus_tag="VW361_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU9743826.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(27486..28616)
                     /locus_tag="VW361_000734"
     CDS             complement(27486..28616)
                     /locus_tag="VW361_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU9743827.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(28700..29089)
                     /locus_tag="VW361_000735"
     CDS             complement(28700..29089)
                     /locus_tag="VW361_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU9743828.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(29105..29488)
                     /locus_tag="VW361_000736"
     CDS             complement(29105..29488)
                     /locus_tag="VW361_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU9743829.1"
                     /translation="MLEVAYILVALAVIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(29489..30277)
                     /locus_tag="VW361_000737"
     CDS             complement(29489..30277)
                     /locus_tag="VW361_000737"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU9743830.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(30270..31205)
                     /locus_tag="VW361_000738"
     CDS             complement(30270..31205)
                     /locus_tag="VW361_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU9743831.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(31335..31511)
                     /locus_tag="VW361_000739"
     CDS             complement(31335..31511)
                     /locus_tag="VW361_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU9743832.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(31651..32358)
                     /locus_tag="VW361_000740"
     CDS             complement(31651..32358)
                     /locus_tag="VW361_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU9743833.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            32509..33537
                     /gene="queA"
                     /locus_tag="VW361_000741"
     CDS             32509..33537
                     /gene="queA"
                     /locus_tag="VW361_000741"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU9743834.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKKNGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHSIQEHYRFFS
                     FGDAMFIY"
     gene            complement(34198..35325)
                     /locus_tag="VW361_000742"
     CDS             complement(34198..35325)
                     /locus_tag="VW361_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9743835.1"
                     /translation="MNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRFEKDETKYRSENPVTIDGEDGYVTTTRTYDVNPETGHVTEKVTVD
                     RKEATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVIVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNTSGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(36040..36591)
                     /locus_tag="VW361_000743"
     CDS             complement(36040..36591)
                     /locus_tag="VW361_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9743836.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(36941..37765)
                     /gene="nadE"
                     /locus_tag="VW361_000744"
     CDS             complement(36941..37765)
                     /gene="nadE"
                     /locus_tag="VW361_000744"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU9743837.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(37762..39222)
                     /locus_tag="VW361_000745"
     CDS             complement(37762..39222)
                     /locus_tag="VW361_000745"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU9743838.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIYNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRLVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFPEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(39338..39826)
                     /locus_tag="VW361_000746"
     CDS             complement(39338..39826)
                     /locus_tag="VW361_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743839.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(39816..40025)
                     /locus_tag="VW361_000747"
     CDS             complement(39816..40025)
                     /locus_tag="VW361_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9743840.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
BASE COUNT        11971 a         9179 c         7587 g        11521 t
ORIGIN      
        1 cctccctata tatttttgat taccaatctt aatcatttac aactacattc taacaaacta
       61 taaaagcgtt tgtcgaattg aatttatcaa gcaagcgacc aaccagctca tcttttttct
      121 atttctgcca atatgcgtga caggtaataa tgatagccaa aaatagcaag agcaagcagg
      181 aggataagag ctcctactcc caagctgatg gcaaggatag gggagagaga ctgaaccaag
      241 aatatactcc caattacaag ggccatcagg attgcactat aaataaacaa taaaataaac
      301 aataaaacta tggcgactat gccatttgaa cgattcacca ggtccgtaat gctactccaa
      361 ttggttgaca gatttttcac atccttaaaa taatggtgac aagaaaggat gacactggca
      421 aggatccatg ccacaataag gtaaatcatc gaaaggatgg gcaagcctag atatagagaa
      481 agaccaagta aagtcagaac tggtaaaaag gactgaacag caaagataat ccaaaatttc
      541 actttcacat aacgagcaaa gtcaaagggt aaactcttca gaaaatcaac attttccctc
      601 tccaaggaca aggcaattga aggcaggctg gtgatattgt tattgacaac tgctataaag
      661 agagctataa aaaaagggta accagtatgg aggatgaatg tctggaacta tctgagaatc
      721 tcggattttg gaaatcagac cgatcatcat gagataagga aggaaagcac ttgtaaaaag
      781 cactgtaacc acgccagtcc cctgtcccaa gagggtgagg tggtagcgta aaaccatgcg
      841 gaaaaatccc tttttagtgg ttgaaattct ctccttgctg cgacgttctt ttttgacctt
      901 ctcctcacta ttaagcagga tcacgtcata aaaacgagga aggaccttct ttttggtcag
      961 ataaagcagg aagagagtta gtcctatcca agcgagcaga cccaatatgg cttctattga
     1021 aaaaggctcc actgctattt tgtaaaagat atgaagagga taaaggagaa atggaatgtc
     1081 tctaactttg tcaacaatac ttccaaaagt cgactgaaga aagaagataa atattaaagg
     1141 tatgagaact cctatcccaa tcatcacatt cgaaaaaata gactgatact ttctgaagac
     1201 cctagtctga gccaagaaat gtactgccac taccgtcact aaagtaacag agacaaataa
     1261 taaggtcaag gacagtagca tcaaaggcaa acccagccaa agagaaggag ctagactaat
     1321 atagagggct agaaaataag ctaggattgg tacaattcca gttagagctg gcaagaggac
     1381 agacagtcct ttagcaatta taatctctga ttctttaaaa gcatagggac tataggaggc
     1441 caggtcctta ctctcataaa agacattgta aaatgcagtt aaagaagttg aaaaggcaat
     1501 cactagtaaa atagcaacca cgaaactaaa ataaacaggc atttcctcaa aaggaaaatg
     1561 aatggctata gtactaaaaa agatgagcat caagagactg gaaaaaatgt aagaacttag
     1621 gactctagcg gaaacattta ctttttttcc agtattttta gcttgcttct ttcgtaggtt
     1681 agccagatta gcttctttag atgaatagag gatattgata tcaactaatt ttttaatgac
     1741 cttgagacgc atctgaaacc tcctcttttc taccagcaag gctaaggtag atactttcca
     1801 aagactggtc tgggttgtct tttctcaagt cctctacctt accacaataa atcaaatgcc
     1861 cctttttcaa aatagcaatc cgatcacaga cttgctcagc tacctctagc acatgagttg
     1921 aaaacaaaac tgtcttacct ttttgcgcat gctccttcat catttgcttc aaatcaaagg
     1981 cagcctgggg atccaaacca gtcaagggtt cgtccaagac ccaaatatca ggatcagaca
     2041 agagtgcccc gatgacaaaa actttctgac gcattccatg agaaagggtt tcaataacct
     2101 gataacgatt ttcagcaaaa tcaaaaacgt tcaataacct agctaaacta gcttccaagt
     2161 cagagctgct caaatcatag gatgaagcaa tcaattccca aaattcattg gccgttaaac
     2221 gtaaaaataa gtcaggcgaa tctgctacgt agccaatctt tcgtttgatc gccaagcgat
     2281 tttccgataa ctcctgacca tctaccaaaa tacgaccact gctgggtgaa atgatactga
     2341 ctagggattt tatggtggtc gattttccag ccccattatg accaatcaag cccataatct
     2401 ctccattttc aatctgcaaa ttgagattac tcaaggcctc tttatcacca tacaacttac
     2461 taacattttg aaattcaatc atgggatgac tcctatcttt atctatatta aatactatta
     2521 tactagcact ttgatacaaa aaaatcaaca ctttatttta agtagataca atagtttcct
     2581 tctattctta cgcaaacgtt tgcgctaacc aatactttat gatagaataa agaacaagat
     2641 tgacaagtaa gaggaaaaat catgcaaaat caaacgctca tgcaatactt tgaatggtat
     2701 ctgccccacg acggtcagca ctggacgcgt ctggctgaag atgctccaca cctagctcat
     2761 ctggggatta gccacgtctg gatgccacca gcttttaagg caaccaatga aaaagatgtc
     2821 ggctatggtg tctatgactt atttgaccta ggagagttta accaaaaagg gactgtccgc
     2881 accaagtatg gtttcaaaga agactatctt caagccattc aagccctaaa agcacaggga
     2941 attcaaccta tggccgatgt ggttctcaat cacaaggctg cagccgatca catggaagcc
     3001 tttcaggtta tcgaagtgga tcctgtagac cgtacggtta aacttggaga acccttcacc
     3061 atcaatggct ggactagctt taccttcgat ggtcgccaag atacctacaa tgacttccac
     3121 tggcattggt accacttcac cggtacagac tacgatgcaa aacgccgtaa gtctgggatt
     3181 tatctcatcc aaggggacaa caagggctgg gctaacgagg aattggtcga taacgaaaac
     3241 ggaaactacg actacctcat gtatgccgac ctagacttta aacatcctga agtcatccaa
     3301 aacatctatg actgggctga ttggttcatg gaaacgactg gtgtagctgg tttccgtttg
     3361 gatgccgtta agcatattga ctctttcttt atgcgcaact tcatccgcga tatgaaggaa
     3421 aaatacggtg acgatttcta tgtttttggt gaattttgga acccagacaa ggaagccaat
     3481 ctggactatc tcgaaaaaac ggaagaacac tttgaccttg tcgatgttcg tctccaccag
     3541 aatctctttg aagccagtca agctggcgca aactatgacc ttcgtggcat tttcacagat
     3601 agcctggttg aactcaagcc tgacaagtct gtgacttttg tcgacaacca cgatacccaa
     3661 cgaggacaag cccttgagtc taccgttgaa gaatggttca agccagcagc ctatgccctc
     3721 attttgttac gccaagacgg ccttccatgt gtcttttacg gagactacta tgggatttca
     3781 ggccagtatg ctcaacaaga tttcaaagaa atccttgacc gcctcctagc catccgaaaa
     3841 gatttggcct atggagaaca aaatgactac tttgaccatg ctaactgtat cggttgggta
     3901 cgttcaggtg ctgaaaatca atccccaatc gcagtcttga tttcaaatga ccaagaaaac
     3961 agcaagtcaa tgtttgtcgg tcaagaatgg actaatcaaa cctttgtaga tttacttggt
     4021 aaccaccaag gtcaagttac aattgatgag gaaggttatg gacaattccc tgtctcagct
     4081 agatccgtaa gtgtctgggc agtcaatacc atctaatagc tcataataac caagctaggt
     4141 ccaagcggat ttggcttttt tgtattcaca aaaagaccta cccaaatgga tagatcttta
     4201 cttgattaca atttacctgc tactgcatcc aacaattctt ggatcttagc ttggttgctt
     4261 cctcctgcca tggccatgtc tggtttacca ccaccacgtc catcgatgat tagtgctaat
     4321 tctttgacaa ggtttcctgc atgaaggtct tttgtcttgc ttgctacaag gacattgact
     4381 ttgtcaccga tagcggcaac taggacaaga agatcagagt agtctttttg tttccagtta
     4441 tctgcaaaag tacgaagggc accggcatcg gatacagaca cttgactagc aatgtaacga
     4501 tgaccgttga cttccttaac atctttgaag atatcgcctg cggctgcagc tgcggctttt
     4561 tctttcaact cagcattttc tttttgaagt tgacgaagtt gttcttgaag tccttctacc
     4621 ttgtgaggta cttccttgac ttgaggtgct ttcaaggttg ctgcgacagc tttaagagca
     4681 tcctcttgtt cacgataggc ttcaaaggct tccttaccag tcactgccaa gatacggcga
     4741 gttcctgaac cgattccttc ttctttgaca attttgaaga gaccaatctc agaagtgttg
     4801 ccaacatgag taccaccaca aagttcaata gagtagtcac cgatagtcac gacacgaact
     4861 tccttgccgt atttctcacc aaagagggcc atagctccca tttctttagc agtgtcaata
     4921 tccgtttcaa ctgtcttaac ttcaagagct tcccagattt tttcgttgac ttgctgttca
     4981 atcgcacgca attcttcagc agttacagct tggaagtggg taaagtcaaa gcgaaggaat
     5041 tcaacttcgt taagagatcc tgcctgtgtt gcgtggtttc caaggatatt gtgaagggca
     5101 gcgtgaagca aatgagtcgc agtgtggttt ttcatgacac ggtgacggcg attgctatca
     5161 attgccaagg tatattcttg gttcaaggca agcggtgcaa ggacttcaac tgtatgaagg
     5221 gcttgaccat ttggggcttt ctgaacattg gtcacagtag ccacaacctt acctgactca
     5281 tccaagattt gtccgtagtc agctacctgt ccacccattt cagcataaaa tgacgtttcc
     5341 gcaaagataa gagaggcagt tccttctgaa acagcttcta cttctgcatt gtccgccacg
     5401 atagctacca atttagaaga caattggcta gcattgtagt tgaaggcact ttctacagtg
     5461 atgttttgaa gagtttcatt ttgcataccc attgagccac ccttgacagc tgacgcacgc
     5521 gcgcgttctt gttgttcttt catggctgct tcaaaacctt cacggtctac agtcatacca
     5581 gcttcttcag cgatttcttc agtcaattca actgggaacc cataagtatc atagagtttg
     5641 aagacatctg aaccagcgat aacagattga cctttttctt tcaagtctgc tacaatgcct
     5701 tgggcaaagt gttgacctga gtgaagggta cgggcaaatg attcttcttc gctcttaacg
     5761 attttctcaa taaagtcacg tttctcaagc acttctgggt agtagctttc catgattttt
     5821 ccaacagttg gaacgagttt gtaaaggaaa ggctcgttga tacccaattt ttgaccatgc
     5881 atagaagcac gacggagaag acgacgaagg acataaccac gaccctcatt tcctggaagg
     5941 gcaccatcac cgatggcaaa tgaaagtgaa cggatgtggt cagcgatgac cttgaagctc
     6001 atgttgtcgc catcttggtc ataaacctta ccagacaatt tctcgacttc acggataatc
     6061 ggcatgaaga ggtccgtttc aaagttggtc ttagcccctt ggataacggc caccaaacgc
     6121 tccaaaccag cgcccgtatc aatgttctta tgtggcaatt ccttgtattc gctacgagga
     6181 acagcagggt ctgcgttaaa ttgtgacaaa acgatgttcc agatttcaat ataacggtcg
     6241 ttttcaatat cttctgcaag caggcgaaga ccgatatttt ctgggtcaaa ggcttcccca
     6301 cggtcaaaga agatttctgt atctggtcca gaaggtcccg caccgatttc ccagaagttg
     6361 tcctcaattg gaatcaagtg acttggatcc actcccactt caatccagcg gttgtaagaa
     6421 tctttatcgt ctggatagta ggtcatgtaa agtttttcag cagggaaatc aaaccattca
     6481 gggcttgtca aaagctcata agcccaagtg atagcttcgt cacggaagta atccccgata
     6541 gagaagttcc ccaacatttc aaacatggta tggtgacgcg cagtcttccc tacgttttcg
     6601 atgtcgttgg tacggatagc cttttgggca ttggtaatac gtggattttc agggataatg
     6661 gtcccgtcaa agtatttctt aagggttgct accccagagt tgatccacaa aagagttggg
     6721 tcatttacag gaaccaaact tactgatggt tctactgagt gacctttggt cgcccagaaa
     6781 tcaagccaca tttggcgtac ttgtgcacta gatagttgtt tcatattgtc tccttattca
     6841 cttgtttaat gtgattggct ttccagtatt tccacatagt caatcgcgac acagagggaa
     6901 atgactaggt ctgcataagc gtcttcaaga accgttacgg tataggtaga ggtcagatgg
     6961 aagagttcct tcttaatttc cgcaatcaac tgatcgcgat catccagcaa tttgaaattc
     7021 aaatcccaga tattgccctc gatacgaaga cctagattat caaactcata cttatctcgc
     7081 caaaaggtca acttcttacg aatgacaaaa ctcgagccat cccgaagctg aatctcaaaa
     7141 cgaggaagca aggtcaagat ttctttactg atctgactga cttgttcacc agccgcatca
     7201 tagatggtaa aagttttggg aatcttaaaa aatgatccct ccacctgata ggcaatttct
     7261 cccctgtcat ccttgatagc gaagcgttcg cctccaagac gaaacttttg tttgacaaga
     7321 aatgttttca tcaacacctc caaaaatcaa aagacaagct catatcacga agggcgaaaa
     7381 accgcggtac caccttcatt caatgaactt gtcattctct tgttcttatg caattgtatg
     7441 attgagtagc atgacttcct agcttagatg gctcgcagca ccgccatttc tctggactaa
     7501 gacaagtgaa aatcaattct caactttctt attataacgt ttttttaagc ttgcgtcaac
     7561 tggaaatgat ctccgttgaa ttagaccaat tccctacatc tctgattact ttttcaggat
     7621 atattttttc ttactgccgt ttttcttttt atcccaaatt ttcatattac taaacacagc
     7681 tactagaata tttccaaata taaaggtgcc tatcacccaa tatatggact cagttgttag
     7741 gtattgtcga tccaagccat cctttaaatg gaatagtata acagtttggt taacaatcat
     7801 aaaggttggc cagaaacttt ttttgaaaaa agtagacatt ttcattattt gttgccgctt
     7861 tctgtaaggt taatactcaa taaaaatcaa aaagcaaact aggaagctag cctcaagctg
     7921 tacttgagta cggcaaggca acgctgacgt ggtttgaaga gtataggcta agtatactac
     7981 taggcaagca aataagcaaa taaacaacta gaatagaaaa agatagggct ctaaaaactg
     8041 acttctattc cttaaaaacg aaccagcttg actgattcgt cttcttacgt ttatctccta
     8101 cttccgatac attttaaact gtaggaagag gtcgctatat ttccctgtcc atttatggtc
     8161 aaatttctca taaacttcta ggtgtttcat ggtttcaaca tcgggataga aggccttatc
     8221 ttcctttgtt tcctctggga gcaatttctt cgctggtagg tttggtgttg aatagccgac
     8281 atactccgca ttttggagag cattttcagg tttcaacata aagttgataa aggcataggc
     8341 tgagttttgg tttttaactg ttttgggaat gaccatattg tcaaaccaaa gattgctggc
     8401 ctctgtcggt accacataac gtagattttc atttttttct aacatttggc tggcttcacc
     8461 agagaaggtc acgccgattg caacattatt ctgaatcata tagcccttca tctcgtccgc
     8521 aacgatagcc ttgatatttg gagtcagttt gtagagctta tccactgtct cttccaactg
     8581 ctgcaattcc ttggagttga ggctgtagcc gagggaattg agccccagac ccagcacctc
     8641 acgcgcccca tcaaagagca tgatagaatt cttatactcc ggcttccaaa ggtcatccca
     8701 atgctcaggc gcttcatcta ccatggtttc gttgtagaca attcctaagg ttccccagaa
     8761 gtaagggatg gagaatttat tacctgggtc aaaggactgg ttgagaaact ctggtccgat
     8821 attttcgatt ccttcaattt ttgaataatc aagcggaacc aagaggtctt cgtccttcat
     8881 cttgttaatc atgtattcac ttggaatggc aatatcgtag gtcgttccac cctgctttat
     8941 cttagtgtac atggcttcgt tggagtcaaa agtctcgtac tgaacttgaa ttcctgtttc
     9001 ttctgtaaac tgagtcaaga gttcaggatc gatatagtct ccccagttat agataaccaa
     9061 tttttgacta tctcgactat tgattttact atctaaatga gtcgcaattc cccacaagac
     9121 aaggataatc gctgcaattc ctgctaaaaa tgaatagatt tttttcatgc ttgctcctcc
     9181 ttctcacgag agataaagta ataacctaca actaggataa tactaaagag aaagactaga
     9241 gcagacaggg cattgatttc taaggaaatc cctttccgtg cacgagagta aatctcgact
     9301 gacagggttg aaaagccatt tcctgttaca aagaaggtca cggcaaaatc atccagcgaa
     9361 taggtgaagg ccatgaagta acctgcaatg atagacggag tcaggtaagg aagcatgatt
     9421 tccttaaaca tctgaaattg actagctccc aagtcatagg ccgcatgaat catgtcgcca
     9481 ttcatttcct tgagtcgagg caaaaccatc aagaccacga taggaatgga gaaggccacg
     9541 tgactagata gaacggtcaa aaagccaagt gaaaacttga gttgggtaaa gagaatcaag
     9601 aagctagcac caatcataac gtcaggcgca accatgagga tattattgag tgatagaaag
     9661 gcttcttggt atttcttacg agactggtag atgtaaatgg caccaaaagt cccgataatg
     9721 gtcgctatca aggctgatag gaaggccaag aaaaaggtct gagccaaaat cagcatgagt
     9781 ctcccatctc caaacatggt ttcaaagtga gtccagctaa aacctgtaaa gctattcata
     9841 tcatcaccag cattaaaggc atagccaatc aagtaaaaga taggcaggta gaggaccaga
     9901 aagaccagtc ccagataaag gttggcaaat tttttcatcg ttctctcctt tccttagtca
     9961 cccacatggt gatgaacatg gtcaggatga gaatcacacc gatggttgaa cccataccat
    10021 agttgtcatt ggttagaaaa ttctgctcaa tagccgtccc caaggtgata acgcggttcc
    10081 caccaatcaa acgggtcagc atgaagagac tcaaacttgg gataaagacc gactgaaccc
    10141 cacttcgcac accgttcata gatagaggga agatgacatg acggaaggtc tcccacttag
    10201 ttgcaccaag gtcatagctg gcattgatga gattattatc catatcgtct aagacattga
    10261 aaatcggcaa aatcataaag gggagctcga tgtagcttgc gacaaagata aaggaaaaat
    10321 cggtaaaaag caactgttgt gaaccaattc cgataaattc caagaattgg ttaatagagc
    10381 cattttgacc aaaaatcccg ataaaagcat aggctttaag gagcaaattg atccaggtag
    10441 gaaggataat cagcatgagc cagagttgac ggtgcttgag acgggtcaaa aagagggctg
    10501 ttggatagct gataagcaag gtcacaaagg tcacaatccc tgcataaagc actgagttga
    10561 aactcatttt gaggtaggtc aagttttgtg acgcaaagta agatttataa ttttctaaac
    10621 taaactggcc ttcaatgttg aaaaaggatt gtccgaaaat caagaccaag ggtgccaata
    10681 caaagagggc aatccaaagc atgtagggca ctacaaagag tttagagctt gttttcttca
    10741 tctctttcct cctcgatcgc attgatcaga cctgcttctt gctcttcgat ttccacgtat
    10801 tcttcgatac gagcatcgaa ctcttcttcg gtttcattga gacgcatgat gtggatgtct
    10861 tctggttcaa agtccagacc gatttcctca cccacgatgg ccttacgggt tgagtggatc
    10921 atccattcat ttccaagttc gtcataggcg ataatttcat aatgaactcc acggaagagc
    10981 tgggtgtcga ccttaacttg gagtttgcct tcttcaggaa gggtaatgcg caagtcctct
    11041 ggacgaataa cgacctcaac aggttcattt ggcttcatcc caccatcaac cgcttcaaag
    11101 cgtttgccgt taaattcgac caagtagtcc tcaatcatgg tacctggcaa gatgtttgac
    11161 tccccgataa aagtggcaac aaagtggttg attggctcat cgtagatgtc cacaggggtt
    11221 ccagactgga caatctcgcc atcattcata acgaaaatcc agtcactcat ggcaagagct
    11281 tcttcctgat cgtgagtgac aaagacaaag gtaatgccca atcgttgttg taattcacgc
    11341 aattcgtact gcatgtctgt tctcaatttc aagtccagcg ctgataaagg ctcgtccaac
    11401 aagaccacac ggggttggtt gatgatagca cgggcgatgg ccacacgctg acgttgtcct
    11461 ccagaaagtt tgcggatgga acgtttttca taaccttcca actgaaccat cttgagaact
    11521 tccgctacac gctgctcaat ttctttctta tcaattttac gcaagcgaag tggaaaggca
    11581 acattttcaa acacattcat atgtgggaac aaggcatagg attggaagac ggtatgtacg
    11641 tcgcgcttgt tggttggaat atcattgata cgaacaccgt ctagcatgat atctcctgtc
    11701 gtcgcatcca gtaaacctgc aataatgttt aggatagttg atttccccga accagatgca
    11761 cctagaaggg tgtagaattt cccttcttcc aactcaaagt tgatgtcttt gagaaccttg
    11821 gtgttgctgt cttcaaaaac tttagagacg tttttgaatt cgataattgg ttttttcaat
    11881 tggcataaat tccttctttt tcatagatta accgatcggg gctctgtcag gtccccacta
    11941 cctcttgcag ggagtaaaac cacctgcata catcttcgct accgataggc tttcacccaa
    12001 gatccggact tctctttcaa gcgtaatacc tgagtgttcc ttgacttttt cgataaccga
    12061 ttggatcaag tcctcgtagt ctttggccgt tccatctgcg acattgatca taaatcctgc
    12121 atgcttttct gacacttcta cgccaccgat acgatagcct ttcaagccag cttctgaaat
    12181 taactgacct gcaaaatgcc cgactggacg cttaaagacc gagccacaag atgggtattc
    12241 caaaggttgc ttgagttcac gtaggtgcgt caagcggtcc atttcctgct tgataacctg
    12301 atgggttcct ggagctaggg caaatttaac tgacaagaca actgcaccag actcctgaat
    12361 agctgaatgg cggtaaccaa aagccaagtc tttagcagac agggtttcga tttctccatc
    12421 cttggtcaag accttacaag actgcaagat gtgagcaatc tcgccaccat aggcacccgc
    12481 attcataaag acagcaccgc caacgcttcc tggaatacca caagcaaact caaagccagt
    12541 taaactatga cggagggcaa tgcgagttgt ttcaatcaag ttagccccag cttctgcttc
    12601 aatggtatag ccatcaacag aaacgttatt gagcttgtca cacaagatga caaatccacg
    12661 aatcccacca tcacgaacga tgatattgct tgcattgcca agaaccatcc aagggatatt
    12721 ttcttggttg gcaaatttca caacgcgagc caactcaaaa cgatttcgtg gaaagaccaa
    12781 ataatcagcc tctccaccta cttttgtata actatagcta tgcaagggtt ccttaaaacg
    12841 gatatcaatt ccttctaaga tttcaagcat tttttctctt acagacatgt cactcttcct
    12901 tttacaaaat tcattccatt ataccatttt tagagacatt tgacgaccat aaaaatacct
    12961 tgtttggatt ttgcataaga aaaagaggtt cccccctttt tatgattttt tacaaaagat
    13021 ttccttggtt ccataggcga ccagaacgag ctccagtgct agaatcactt caaccaagac
    13081 tggatttgtc aaccagccta cttggaaaag agatggtgcc agatcaaaga aggcatgcaa
    13141 gccataggct gctaggagat aaatccattt cttctggcga acagcttggt aaacccaaac
    13201 tgtcaaaagt aattggaaac caagcgccaa gattcgctca aaaccaagca aataaatctg
    13261 ccagaccgaa agtgactgaa tggtttttaa catattttca gacagtaatt gcataacctg
    13321 tgctgtggat tctgagtttg aactgccgaa agaacgatgt aaagattgag taaactagta
    13381 aggcctagaa aaatcaactc caagccacca tgccctaggc cataggccaa ggcatctgcc
    13441 ttttccaaac ttctcttttt ctccaaccat ttgaagaaaa caagacgagc cgtttcctca
    13501 aaaaatgctg ccatggctag gccatagata atatagataa gcggatgatc ttgcaagagg
    13561 gcaatactac cgtctttttg agggtgcaaa atcaagatat gcaccagttt ttccaaaatc
    13621 tgcgaagaga caaagaaagc gactgcaccc aagcccaaga cagctagatt aatctgatat
    13681 ttctttttgg caaaccaaat gcttcctatc agaaaagcta gcaacagcaa catggtaata
    13741 atgatatgaa tggtcatttt cttctcctat tctgcctttt caatatcttt tttcatctcg
    13801 tcaacattga acttagcaaa caagtattga cggtcttgga ctgggaaacg ttggtccaac
    13861 tggtcaactg ctcccacctc gataatgcct tccttgatga caaaatccat gacatgtcca
    13921 ccgaaggtca aatcatctga tatgaagtgc agatggtagc ctgccacact gaccccatgg
    13981 aaaatctcag gcgtccagaa accaacaata gtccccgcaa cattgtcacg actatattcc
    14041 ggttgatggg ttgcgacatc agcaaacttg gtatcgggtg ttgacttagg aatcatacgc
    14101 acatgcatat gtaaaaattc cccccgaatc ttgatagagc ggaaaagatt ttccccatca
    14161 taataagact caattcgttc tttcaattcc ttgtctgtca tctcaaagcg ctggcgaaaa
    14221 atgacctctg cctgatgcgg taccactgca gcgtaaggaa taagggcatc tggtgacact
    14281 tccacaattt ctggctggtc tcctgaccct ttggcctgat aagccttgcc atccaagaca
    14341 atcaattccc catcaatgga atccaaggtt cccaaaccaa ggtcaccatg ttctagcaat
    14401 tctcctactg tcatagtacc accataaagg ccagccatca aggctccaag agtattgtat
    14461 tgaaataatt tcactggttc ctgcacgttc ttatccattc actttcttgt ctgttattct
    14521 ataaatctta ctcctaagta taccacattt gcccctagat gtgaacgaga gaaacgctct
    14581 agacattgcc aagaaggaaa aaaaagggta caatgtaaca aaatcaaggg aggtctggaa
    14641 tgaagaaaca aagcaagtac aaagaggtcg tttcctatct gaaaaatggt atcgagtctg
    14701 aacgatttcc gacgggtagt cgcctgcctt ctatccgtca actgagcctt gactttcact
    14761 gcagcaagga caccattcaa cgagccctgc tggaattacg gcacgaacaa tacctctatg
    14821 ccaagcctca gagtggctac tatgtattag aacaagggca acatcaagac ctagaaatcg
    14881 aggttaccga cgaacatgcc agtgcctatg acgatttccg actctgtgtc aatgaaacct
    14941 tgattggacg agaaaactac ctcttcaact actatgacaa tcaagaagga ttagaagacc
    15001 taagacagtc cattcacaaa ctcctatttg agcaagctct ctactgcaag gctaaccaac
    15061 tagtactgac ttctggaacc caacaagcct tgtttatcct ctctcaaata tcctttccta
    15121 gacaagccaa ggaaatcttg gtggaacagc caacctacca tcggatgaat cgcctcttga
    15181 ttgcacaggg gctggactat caaacgattg aacgaggcat tgatgggatt gacttggagg
    15241 agctggaagg ccacttcaaa acaggaaaaa ttaaattttt ctacaccatt cctagatttc
    15301 actatcctct gggacattcc tattctgagc aagacaaact atctattctt aacttagctg
    15361 ccaagtatga tgtctatatc gtagaggacg attatctggg tgatttggac tccaagaagg
    15421 gccaaacctt ccactatctt gatacagagg agcatgtcat ttatatcaag tccttctcga
    15481 ccagcctttt tcctgccctt cgtattacag cactcattct tccaaatgct atcaaagaag
    15541 catttgtggc ctacaaaaat atcctagact acgacagcaa cctcattatg caaaaggccc
    15601 tgtcactcta tattgacagt caattgtttg aaaaaaatcg tttggctcgc ttgaccaatc
    15661 atgaatctta ccaaaaacaa atcgaggaaa ggataactaa aacaccttgt ccccttcctc
    15721 attatcccct acacgatggt ttattgctag acctgagaca gtatcctaaa atcgccagtc
    15781 tcaaacacag tcaactgggc ttggacttct ttgaagaggc ctatttaagc acctgtcctt
    15841 atcaatttgc caaggtgtcc ctagacaatc tggaaaatgt tttaaactat ttaaaagcag
    15901 aattggaatg acatccaact ctgctttttc ttattcttca acttcagtta gacttgctgc
    15961 tttttcaaga tagctttggt aagttccttc atccttaagt ttttggatga ccttgtctac
    16021 cacttctttc aaatcatcac tattttttct aagagcaacg gcattggcgt cgccgtcctt
    16081 catcttcaag ctgacagttg cgacagctaa gccagcgttt ttagcagcat aactaagtgc
    16141 aacaggctca tccatatgaa cagcatctat ttttccagcc tgcaattcat tgactgcttc
    16201 acccatatta gttagggaag ttaattgaac ttttggcaat tgttccttga ccattgattc
    16261 tggaacagtc cctttttggg ctgcaatatt agcacttttt aggttagtta aatccttgta
    16321 tttttccaca tcagccttac gaaccaagaa actaatcttg ttttcatagt atgggattga
    16381 aaaatcaaag acttcttttc tctcgtcagt agcactaatt cctgcaactg ctaggtcagc
    16441 cttaccagtt tgaagactgg tcaaaacatt atcaaaactc atgcttgaga tttccaactt
    16501 aaccccaagt tcatcagcga tagcctgagc catgtcgatg tctgcaccga ctacctggtc
    16561 ctttccatca accaatgatt gaaattcaaa gggtgcatag tcaggactgg ttgccacaac
    16621 taatttcccc ttttgcttaa tggcctcaac agctgactga gaaccattag aacctgactg
    16681 gcaagctact aagaagaaac ttgcaagaaa attacataaa acaaatatcc atttttttga
    16741 tttcataaat aaacaacctc tctgttaatt ttgtataatt ataacgatat ccaagttact
    16801 tgtcaagtgt tttttaaatt tttatctcaa aaatattttt tcgttcaaaa aaaggagcca
    16861 tcagttgatt tcaagctcct ttttatacag aattaaacta ttttatagtt cgacaatctt
    16921 acctgtttca aagtagacaa cccattcaca gatattttta gcatagtcac cgatacgctc
    16981 caagtaggaa ataacttgga aataatcacg acccgtaaca atggcttctg gatttttctt
    17041 aatctcttca gtcgcaaggt cacggatagt ttcaaaatag tggttaattt gctcatccat
    17101 ggaggccacc cggtatgcgt cgtcaacaga accattaaga taaagatcaa gtgctgcttc
    17161 aacaacgctt ttaacttcac gtcccatttt tttaatttct tcctctacag ctggaatgcg
    17221 ctcttccccc ttcatacgga tggttgcctg agcaatggct acagcgtgat cccccatacg
    17281 ctccacatct gatacagcct taaggacagt caagactgta cgcaaatctt gagagactgg
    17341 ttgttggagt gcgatcattt caaatgattt cttttccagt ttcacttcgt attcatttac
    17401 ttctgcatca tcttcgatga cctcttttgc caggtcacgg tcatgcgtga caaaagcacg
    17461 taccgtacga ttgatttgtg agagcacttc ttgtcccata gcgtagaact ggttatgtaa
    17521 tttctctaaa tcttcttcaa attgagatcg taacatcttt catctcctta tccaaatttt
    17581 cctgtaatat agtcttccgt ttccttgtgt tggggattaa ggaacatctg cttggtatca
    17641 ttaaattcaa tcaaatctcc atctaggaaa aatcctgtct tatcagagat acgtgaagct
    17701 tgctgcatgg aacgggttac cagaagcatg gtgtacttgt cttttagacc atacaaggtt
    17761 tcctcaattt taccagctga aatcggatcc aaagccgaag ttggctcatc caagaggatg
    17821 attttaggac tagttgccaa gacacgggcc acgcagacac gctgctgttg accacctgac
    17881 aatccaatag ctgaatcata tagacgatcc ttgacctcat cccagataga ggcaccttgc
    17941 aaggcttttt ctacggcttc atccagaacc tgcttatcct taattccatt gatacgaagc
    18001 ccgtagacaa cattctcata gatagtcata gggaaaggat taggttgttg gaaaaccatt
    18061 ccgatttcct tacgtaattc aaccgtatct gtacgcggac tgtagatgtt gtgaccattg
    18121 tacaccacgg atccagttgt ggtcacctct ggattgagat ctcccatgcg gttgagagac
    18181 ttgaggaggg ttgacttccc tgatccagat ggaccaatca aggctgtaat ttccttaggt
    18241 tggaaagata gggaaacact attcaaagcc ttctttttat tataataaac ggacaggtct
    18301 gatacctgta aaatcgcatc tgtcatacgg tttcctttct aaccaaagtg accagataca
    18361 tagtcattgg tggactgtag cttggcattt tggaaaatag ttgcagtctt gtcatactca
    18421 atcaaatcac ccaagtaaaa gaagcctgta tagtcacttg cacgagcagc ctgctgcata
    18481 ttatgcgtta caatgatgat ggtaaagttt ttcttgagct caaacatggt ctcttctagt
    18541 tgcatggtcg caatcggatc caaggctgag gctggctcat ccattaagag gatatctggc
    18601 ttaacagaga tggcacgagc gatacagaga cgttgttgct gaccacctga taaggtcaag
    18661 gctgacttgt ggagatcgtc tttaacctga tcccaaaggg cagcctgact aagggaggtt
    18721 tctacgattt catctaggac ttgcttatcc ttaactccag cacgttcatg cgcaaaggta
    18781 atattacggt aaattgactt agcaaatgga ttggggcgtt gaaaaaccat tccaatgtgt
    18841 ttacgcattt cataaacgtt gatttctgga cggttgacat caattccacg atagagaatc
    18901 tgcccagtta ctttagcaat atcaatggta tcattcatgc gattgagact gcgtaagtag
    18961 gtagatttcc ccgatcccga cggaccaatc aaagctgtaa ttttatttct ttcaaattgc
    19021 atatcaatcc ccttaatgga ttcattttta ccatagtaaa catggacatc cttagtagaa
    19081 agggctactt tttcttcagg aaaggtaagg atatgcttct catcccagtt atatgttgac
    19141 atggcttctc ctttaggcag cggttaattt cttgtgtaga tagcttccga acttacgagc
    19201 tccaaagtta aaaatcagga taaagatcag gagcacagcg gcagaacctg ctgatacaat
    19261 ggttccatct ggaatagtgc cttcactatt gactttccag atatggacag ccaaggtttc
    19321 tgcttgacgg aagatagaga tggggctagt cacactgagg atattccagt tagaccagtc
    19381 aagagctggc gccgattgcc ctgctgtata gatcagagct gcagcttcgc caaagatacg
    19441 accagatgcc aaaacgacac ccgttacaat acctggaagc gcttctggaa taacaacatg
    19501 aaccactgtc tcccagcgag aaatcccaag agccagacca gcctcacgtt gggtatggtg
    19561 aacgtgtttc aaactatcct ctacattacg cgtcatctga ggcaagttaa agactgtcaa
    19621 ggccaaggca cctgaaatga ttgaaaatcc atactcaaac tggactacaa agatcaagta
    19681 accaaagaga cccaccacca ctgatggtaa agaggacaag atttcaatac aagtccgcac
    19741 aaagttggta acaggacctt ttttagcata ttcagccaag taaatcccag ctcccataga
    19801 aagaggtaca gaaataatca aggtaatgac caataggaaa aaggaattgt aaagctgaat
    19861 gccaatccca ccacctgctt gaaaagcaga agaccttcca gtcaagaaag accaagagat
    19921 atggggcaag ccccgaacca agatatagag aatcaaggaa gccaagattg tcacaatgat
    19981 gctagcaatc gtatagagga cagctgttgc aagtttatct aatttcttag cgcgcataat
    20041 ttttctttcc tctttctttc gtaatcaatt taatcacact gttaaaaact aaactcatca
    20101 agagcagtac caaggccagt gaccagagaa cattattatt tacagttccc atgacagtgt
    20161 tcccaattcc catagttaat atagaagtta aagttgcagc tggtgtggtc aaggaagttg
    20221 ggataacagc tgagtttccg acaaccatct ggatagctag agcctcacca aaggcacgcg
    20281 ccatcccaaa gaccactgca gtgaaaatac cagaacgggc cgccttcaag atcacacgcc
    20341 agatagtctg ccagcgagtg gctcccatag cgaaactggc ttcacgataa taacgaggaa
    20401 ccgcacgcaa gctatccgtt gtcataaagg ttacggtcgg caaaatcatg acaaagagga
    20461 cggaaatccc tgacaaaatc ccaaaaccag tcccaccaaa gacactgcga acaaagggaa
    20521 cgacgacttg caagccaata aatccgtaca ctactgaagg aatcccaacc aggagttcaa
    20581 tagctggttg caaaatcttc gccccttttg gtgatacttc ggtcataaaa actgctgcac
    20641 caatagcaaa gggtgttgcg ataagggctg agagaatggt aacgataaag gaacccaaaa
    20701 tcataggaag ggcaccaaat tctttactag aaggattcca agttcctccc aaaagaaagt
    20761 caaagatatt cacaccattg acaaagaagg tcgacaagcc tttttgcgct acgaaaacca
    20821 aaatcatggc cacaaggatg actatcaaag aaagacaggc aaaggtcaaa ccttttccta
    20881 atttctccag acgagaattc tttgatggaa gcaacatttt cttagctaat tcttcttgat
    20941 tcattattgt ctcccttcca acactgtcac agttccggca gcatcttttt caaccttcat
    21001 ttccttaatc ggaatatact tcaatccttt gacaatccct tcttgggtct catccgagag
    21061 aacaaaattg agaaattctg cagccaactc attgggctgc cccaatgtat acatatgctc
    21121 ataagaccac aagggccaat tattgctact tatattttct ggacttaagt catagccatt
    21181 caacttcatg cttttgaccg aatcatctat ataggtaaga gataaataag agatagctcc
    21241 tggacttttt gatacgattg attttaccgc tccatttgaa tcctgctcct gactttgcat
    21301 ggcagactga ccttccataa tgacagtatc aaaggtagca cgagagccag agccggctgc
    21361 ccgattgata acagagatgg gtaagtcctt accaccaacc tctttccaat tggttacctc
    21421 acctatgaag atttgacgaa gttgctctgt cgttaggtta tcaacatcaa cctccttatt
    21481 gacaatcaga gccaagccag ctaccgcgac cttgtggtca acaagagcag aagcatcaat
    21541 tccgtctttt tcctcagcaa atacatctga gtttcctata tcaactgccc cagactgaac
    21601 ctgggacaag cctgtaccag aacctccccc ttggacattg accgtttttc caacatggat
    21661 cgtgccaaat tcatctgccg ctacttcaac caagggttgc aaggcagttg agccaacagc
    21721 cgttatggat tctccacgat caatccagct agcacagcct actaaacaag ccgtcagcca
    21781 aaaagcgata agagacagag caagcttttt tctttttttc actgtttttc tcctcgaaaa
    21841 taattatgaa tactgtgaat tttttaagta gttctttatg agttgacgca tgaattctta
    21901 ccaaatttct gcgcaattga ttatttatat aatataggct atattactct ttcctaacct
    21961 ccttttttca tatgtggata aaatctcttg tctatccctt cccccattgt cacccattat
    22021 agtcatttcg tgtctctttt tccccttttt aatgcaaggg aaattactct tcttagatga
    22081 taatccaaaa gctagaaagg tatctcaaac ctctctactc tcccagacta gtttacaact
    22141 aaaaggaaaa gattctattt tatgagaaat ctagtttaca agcggtaaga acgctaataa
    22201 ctaaacttct tgtactcttt gaaaatctct tcaaagcagt gttttgagct atctatggct
    22261 agcttcctag tttgctcttt gattttcatc gagtagtaaa actacatgtg atggcaatca
    22321 agatatcaag aatcatccta ctaaaaaaat ccatactttc actataacat agaataagat
    22381 atttgactag cattttcatt tgaatctgag gccttttgga aaataatttt tcaaaacatt
    22441 tccagtaacc tttgcaaagc ccaagccatt gcctttaacc aaaacttggt accaaccatt
    22501 tggcagactt tctgccagct gaacggtttc tccagccgca tacttgacaa acgcttcttg
    22561 gccaatttca accgactgtt cgacctgact cggtttcaag gctaaaccaa gagcgaaact
    22621 gggctcaaag cgtttcttct taaaagtacc cagatgcagt ccattgcgag caatcttgag
    22681 cttccctaaa tctggcaaaa gttctggcaa gagataaagc tggtctccaa aaatctgcaa
    22741 gatacccggt agattgacct tcaaatggtt ttgggcaaat tcctgccaca aggcaacttg
    22801 ttcacggctg aggttactct tacttgcctt aaatttagga gctggattgt tacccttaaa
    22861 ctgtagatgg gcaacaaact gaccctctcc cttaaactga tgagggtaca tccgagccgt
    22921 ttcttgcagg tcaataccag ctaccattcc attgatatgc tctactggca acaagtcaaa
    22981 atcatactct tccagcaacc aattgacaat ctcttcgttt tcctcgggtg cccaggtaca
    23041 ggtcgaataa accagacgac caccttcagc taacatggtc actgcatcct ccagaatttc
    23101 tctttgcaag ctagcacatt gactcggata atctaagctc caatagtcca tagcatcagg
    23161 tttcttacga aacattcctt caccagagca aggggcatca agaacgatta agtcaaaata
    23221 gcctttaaag accttgacca agcggtcggc agattcattg gtcaccacga catttgtcgc
    23281 tccaaaacgc tccatgtttt caaccaaaat cttagcccgt ttgcttgaaa tttcattgga
    23341 aacaagtagc ccctcccctg ctagataggc tgccagttga gttgatttgc cccccggtgc
    23401 agcagccaag tccaagacct tcataccagg actgggttgg gctacttgag ccaccatttg
    23461 agcagcaggt tcttgcgaat aaactaaacc tgtagcatgc tcaggcgatt tccctgaaac
    23521 cttcccatag tggccccaag gggtttgagt aatggcatca gaaaaggaaa gttgctcttc
    23581 ttttaaggga ttgacccgaa aggccgaaac cgcttcctcc tcaaaagagg caagaaaatc
    23641 tcttgcctca tctcctagta tttctttata tttttcaaca aatccttctg gaaatttcat
    23701 ttaagttctt ttcctttcgt aaatatagga ctgaatttcc tcctgcatct caagaggcac
    23761 catcatgacc ggctgtctgg tttgaaaatc aggagcttca ccaaaaaggg tcacaacccg
    23821 atagcccaga ctttccccta aaatactagc tgcggcataa tcccatggtt gcagataggt
    23881 gagataggtc aacaaatgcc ctgacaaaat cttggcaaaa ctaatggccg cacttccata
    23941 gacacgaaca ccaagaaccg ctcggctcaa atcagccagc ccccattcat tggtttccag
    24001 cataccacta ttccctgcaa tgagaaaatc tccaagtggt ttagttttaa aaggagctag
    24061 gggcctatca tttagacaaa ctggaaattc cccaccaccg tggtaacaat cccctttgac
    24121 cacatcataa atcagaccaa actgtccctg accattttca aaataagcca tcataacagc
    24181 aaaatcttcc tgctgggcta caaaattatt ggtaccatca atgggatcaa tgacccaaac
    24241 cttgccctct tgaaccgagg ctcgcagaca accttcttca gcacaaatct tatcctcagg
    24301 ataacgggac aaaatctcac caaccaagag ttcctgaact tctttgtcca gtctggtcac
    24361 caaatctgtt ggagaggact tggtttcaac acgcaagtct tcctgcatat ggtcaagaat
    24421 gtactggcct gctttcttaa caagctcttt agcaaattca aatttacttt ccaagagaaa
    24481 tctttccttc ccctttttct ttggcagcct gaactgctcg gtaaagtgaa tagccactaa
    24541 ccgtttcaaa ttctcgtccc aaacgtttct cttcgctctt gcttggcacg accgctttga
    24601 atcccttata ggagtccagt aactttttag cctctacttt gccttcatag gcagcttcaa
    24661 catcattaaa aaaagaaagc actgaagcaa gttcttcagt gctccacgac aaatctagtg
    24721 ggtaactata ctgtttgttc attaactaat accagctctc attcttgctt cttttagttc
    24781 ttgcttacga taactacgag ggagaaaagc acgaatctca tcttcattaa aaccgatttg
    24841 catacgcttg gcatcaataa taattggacg acgcaaaaga ctaggatact gctcaatcaa
    24901 atgaagcaat tccgataccg aaatactctc tacatcaata ttcaattttt gaaaaatttt
    24961 tgaacgagtt gaaatgatgt catcagtacc attttcggtc aaggaaagga tgtgttgcaa
    25021 ttcttttctt gttaaaggac tggtcataat attgtgttcc acaaagggaa ccttatgttt
    25081 ttctaaccag gccttagcct tacgacatga tgtacagctc ggtgatagaa atagtgtaat
    25141 catgcttttc tcttcttatc tatactttgc tacttctatt atacaaaaaa ataaagcgct
    25201 tgactaggga tttttagaaa aaaagcctat tttttcaaga aaaataggct ttttgcgaac
    25261 gattgacaca attggatttg gttaattcac tcttaacgat ggttttaaac gatatatatt
    25321 tttatatatg taaattaaaa acatctttcc tttcacttcc tacgactttt cagatacaga
    25381 tagccaaaga agttttcata gagggcaaaa aagaggagga aggcatgaag aaagaaggtc
    25441 tctggcaaaa tcataataac aggatccttg gctggatcaa aaagccaggt atcatctccc
    25501 acaaagagaa tttgatggaa aagagtaaag aattggtcaa aaccaatcaa aactccccca
    25561 agtccaatca tcacaggtaa gactactaga gccaggagac tttttcgata aagagacaaa
    25621 aagtcctttt tcacaatcct attgacaaag acatagaaac ttggcagtgt cactagagct
    25681 actagctgaa ccaaatgaaa gagattcttg accactgcga aatggtgcag accagctgct
    25741 gacgaacgaa aatcaggcat ctgtaagacc tgactaaaag gattggtcag ataattcatc
    25801 aagatatgaa aattgtattg aatggtttct ggttttagat agactcgatt cgttaagttt
    25861 agccactgaa tctccatagg atagaaaatc caagccagat aaatggtcag aaggattgag
    25921 agggagagga gaaagagcat agagccccaa aaggtcaatt tagttttcat caaaatccca
    25981 ctccgcaagg ctagaaacca catgtgtcgg tgcgattggc aggccagcca cttcttctgc
    26041 cttagtaaaa cctgtcgtca ccaagagcgt tggaatgcca ttgtcaatcc cagcccggat
    26101 atcagtcaaa taattgtccc caaccatgat taactcttca cgttccaaac ctaagtgctc
    26161 aaccgccttg tccataatga tggcatttgg ttttccgata taaaccggct tcactcgtgt
    26221 cgctacttca agcagcgtaa tcagtgagcc agcacctggc aaaagaccac gttccgtcgg
    26281 gatgttgagg tcaggattgg ttccgataaa atgggcaccc ttttgaatag caagagttgc
    26341 tgtggcaaat ttttcatagt cgacttgcca atccagacca actaccacgt aggcagggtt
    26401 ttccttgtct tccacataac cagccgcctt gatggcttcc ttgagtcctg cttctccgac
    26461 gacatagaca gtcttttcaa gccccaaatc attcatatag tcgatggttg ccaaagtcgc
    26521 tgtgtagaca gtcgatagag gcgtatcgat attaaaattc tgagccaaca tctccttaac
    26581 actctctgga gtgcgggttg tattgttggt tacaaagaga tagggaatgt cccgcttttg
    26641 caattcatga acaaaagtct ctccagcagg gattcggtct ttccccttat aaatggttcc
    26701 gtctaaatca attaaatagc ctttatattt catctatttc tccctaaacc ttttttattt
    26761 cttgccaagt aatgattgct tgggcattga taaccccatc acttgtaatt tcatgcttgc
    26821 tttccagtcc agtccgttca acagccgatg taatcacccc acctggtcga acttccttga
    26881 catacttgag gttgattttc ttgggaatat agtgggtcaa aaaatccgct cccatgacct
    26941 caaaaatcca gtccaagtat ttactgttat tgacatgacc attcatatcc aagtcgtaaa
    27001 aacgaacatg gtaatccttg ctgatcggct cttccaagga ttcatacttc ggtccacgga
    27061 taagtttttt atcaaaatca gactggtaag gagccacaat ctcaggttca acagcatgga
    27121 cttttcgact gtcgcggtcc atgagaacaa aggtcgccat catatggatg agctcctgcc
    27181 ccgcttcatt ataaatagta aagcgacggt agcaaaaaag tcgattgtag ctcaaggctt
    27241 ccgtttcgat ggtaatttct tccgcaaaac gaggcaaacg aaccacctca atatcatatt
    27301 ctgcgataat ccagaccaga ttatagtctt ccaaaatggc cttatcacta actcccagtt
    27361 caatcgattg catccctgaa acttgcagtg acagcaaaat cacatctgga agtttgatat
    27421 gaccgttcat atcagccata tcaaaaggaa ttttcatttt catttgataa gttaagccca
    27481 tgatcctact ccaaaataaa tcgttctgct acagtatctc ccaaaaagag acctctcttt
    27541 gtcatgcgaa cgtggtcacc ctcaatctgc atgaggcctt gttgaaccaa atctctgaca
    27601 atttctccat aaagtccagc aaaagactgt ccaaattttt cctcaaatcg cgccatggaa
    27661 accccggatt tcttgcggag tcccaagaac atttcttctt ccatttgctc cttttgactc
    27721 aggtgatctt ctgtaataca agcattgcct tcctcaaccg cactgagata atgacgaatg
    27781 ggaccatgat ttttatagcg tactccattg acataaccag atgcccctgc accaatacca
    27841 tagtattcag cattgtccca gtacatgaga ttatgacgac tttcaaagcc gggtttggag
    27901 aaattagaaa tctcataatg ctcaaaaccc gctcgctcca gctctgcaat gatgtactca
    27961 aacatctccg cttctagttc ctccttaggc agaggcaatt tcccacgtcg catccggttc
    28021 ataaagaccg tatggttttc taaaatcaaa ctatacaaac tcatgtgggg aatatccaat
    28081 ccaatggctt tagccacatt ttcctttact tgctccatgg tctgaccagg cagagcataa
    28141 atcaaatcaa tggagatgtt gtcaaaacca gccagtttca ggcgatcgat attttcataa
    28201 atatccttct ccaaatgact gcgcccaatc tttttcaaca tcttatcatc aaaggtctgg
    28261 acacctagcg aaacacgatt gacagccgaa tttttcaaaa cagctatctt atccgcatcc
    28321 aaatcgcctg gattggcttc aatggtcaac tcttccaaga cagacaaatc caagttttta
    28381 gtcaagccat tcagtaacac ctccagttgc ggagccgaca gggctgtcgg tgttccacca
    28441 ccgatataaa gggttgacaa cttttcaata tcataagaac gaaactcttc cagcagatgc
    28501 tctaaatagc tgtcgactgg ctgatttttg atgaagacct ttgaaaaatc acaataataa
    28561 caaatctggg tacaaaatgg gatgtgcaca taggctgacg ttggtttttt ctgcatagta
    28621 attattatac cacaaagact agattccaga taaaaatcac catccccaga tacatagtcc
    28681 gtccggagat ggtgatggtt tattcttctg ttatatcaat cacaatctct tctgagtcat
    28741 caagagcttc ggctttttct tgccattgtt ccttgagatt atttaattga ttttttgatg
    28801 cttctgtcgc ttgaaaagca taggatttag cttgagcaag tatactgtcc acagtgattt
    28861 cacctgactc aacctgttct tttgttttca gaacaaaatc tgtagcctgc tccttaactt
    28921 ctgtcagttt ttcacagact tgctccttgg catactccgg atcttctctc aaatcatcta
    28981 gaaaatcttg agcctgactg caaacttgtt tgcccttatc acttgttaaa aacaaggcaa
    29041 gagctgcacc tgaaacggtt cctaaaagga ttgaggataa tttacccata aggattctcc
    29101 ttttttattt tttgaaaaat ttacttgcaa gacgaagagc tgacagactt gcaccagtct
    29161 tgagtgtttt tgaaccagct gatgaagctt tcttgctcaa gacacgcgca tggtcattga
    29221 ggtctgaaac agatagagat aaatctgcaa cagcactgaa gagtggatca atcgtagcca
    29281 ccttgacatt gatatcatct gccaagacat tgaccttagc caacaactca ttggtgtgat
    29341 gcaaggtcac atccacatct gaagtcaagg ttttaatcgt cttttctgtt tcatcgatga
    29401 cacgaccaag cttttgtaca gtaatgatca gatagaccaa aaagacaatc acagctaggg
    29461 caacaagaat atatgcaact tctaacattt agttttcctc ctctgtaata tagtaagggg
    29521 ccttctttcg attttgataa ataacgatca ttataccgag accgataaag acaactgaca
    29581 gccattggga cactcgaagg ccgaagaaca tgagactatc tgttcgcata ccttcgatga
    29641 ccatacgacc gaaaccatac caaatcaagt aaaaggccgt gatatgacct cgtctgagac
    29701 tcttccattt ccgtctaaaa atcagaatca aggcaaagcc aagcagattc catagagact
    29761 cataaaggaa agtcggttga cggtagctcc cctcaatata catctggtca cggataaagc
    29821 caggtagata atccagatta tccactgttg caccataagc ttcttggtta aagaaattac
    29881 cccaacgccc caaactttga gcaatcataa cgctaggcgc cgcaatatct agaaaatccc
    29941 aagtattgat gagtttacgg tcagcaaaga tatagagcac aagagcccca gttatcaaac
    30001 caccgtaaat ggccaaacca ccattccaaa tggcaaaaat ctctcctaaa ttctgactat
    30061 agtaatcaaa tcggaaaata acatagtaga gacgagctcc taaaatagcc aagggaaagg
    30121 ctactaagat aaaatctaaa atatcgtctg gtatgatctt ctttctaggt gcttctttca
    30181 tggtcaaata aaccgcaaga atcaagcctg tcacaataca taaggcatac caacgaatgg
    30241 ctaggggtcc tagttgaata gcaattggat caagcatttt gcacctcatt tcgagctatg
    30301 agacttgtca gtcgttcgtc gaacaaacgg gtagcatcaa agcccatttc cttggcacga
    30361 taattcatgg cagctgcctc aatcacaaca gagatattac gacctgtttt aactggaata
    30421 cgaatacgag gaatggctac gccagaaact tcaagttcct ctgcattgtt tccaagacga
    30481 tcaaaggtct tatgcgtatc gtaattttcc aaatagacag caagctgaac ctgtgaagaa
    30541 tccttgacag cactcgcacc gtagagactc ataacatcga taataccaac cccacgaatt
    30601 tcaatcaagt gtttcaaaat ttcagctggt tcaccccaga gagtaatctc atccttggca
    30661 aagatatcga cacggtcatc ggctaccaaa cggtgaccac gtttgacaag ctcaagacct
    30721 gtctcgctct taccaattcc actatctccc tgaatcaaga cgcccatccc ataaatatcc
    30781 atcaagacac cgtgcacact ggtacgttct gccaaacgag aatccagata gctagataac
    30841 tctccagata aacgactggt agctgcacgg ctggttaaaa tagcaatctt acattctcta
    30901 gcagccttta acatctcctc tggaaccacc aaaccacggg caacaatgac tgctggtgtc
    30961 tcaggtagaa acattttttt caaaacttca taacggctgt tggaaggcat gctgatcaga
    31021 taagaccact ccttcatccc caaaagttga atccgctctg gtgtatagta gtcaaaatag
    31081 cctgtcattt caagaccagg tcgcgtaata tccgctgtat tgatttcctt ttcaagcaat
    31141 tctggttcac catagacaat atctagtcta agcttttcaa tcacttcttt tactaaaacc
    31201 gacatcattt cctccttcaa atgaattctt ctctctatta tatcaaattg taggaggaag
    31261 tttcagattt ttgcaggctt tggagtattt atttaaaaga aaaaggacta gatttctcta
    31321 gcctttcatt tcaattagaa ttttttacgt ttacgagcta cttctgattt acgtttacgt
    31381 tttacagaag gtttttcata gaattcacgt ttgcgtgttt cttgaagagt accagcttta
    31441 gtaaccgcac gtttgaaacg gcgaagtgcg tcgtcaagag attcattctt acgtactact
    31501 gttttagaca tttttttcac tcccttcaag ttcaatatct atttcattct acacgtaaaa
    31561 ggaataattg tcaagcaaaa atgcggttta attttgattt tttcttccat ttatacaaga
    31621 gttgaaagcg ttcaatagaa cattgctttt ttatttttcg agtaagctaa gcgcttcagc
    31681 atctgcgatg atggttacat cagggtgatt ttggaggcta cttgcaggta ggttctcagt
    31741 cactgggcca gatactgttc cggcaatggc ttctgctttc gactcaccat aagcaaaaag
    31801 aataatagac ttggcatcca aaatgttttt aatccccatt gaaatagctt gggttgggac
    31861 gtcttcaatc ttggcaaaga agcgagcatt ggcttcgata gtagactggt caagttctac
    31921 tagatgcgtt tgactatcaa atggagtacc aggctcatta aagccgatat gcccattgcg
    31981 accgattccc aagatttgga ggtcaactgg atggtcagcc aaaatttggt tgtagcgttc
    32041 aacttcagct tcagcattgt ccttaacacc acgaggcaag aaactttctt taaatggttt
    32101 ttggttgaac aagttttctt gcatgaagta acgataagac tgtggattgt ccccatcaag
    32161 gcccacatac tcatcaaggt tgacactggt tagatttgaa aaatcaaggt cactctcaac
    32221 aatttccttg taaaattcaa gtgggctact tcctgtcgca agtcctagag tttgagctcc
    32281 attagccaat ttttccttca aaatctcaaa agcaactttt ccaccttgaa cttggttttc
    32341 aactttaata actttcatct tttcatcctc catttctgtc tatatttatt atatggtata
    32401 gaccaatttt tgtcaagtga aaacgattta atttctaaaa aaagagcgtc caaacttgaa
    32461 acgtgttata atggatagga ttagaactta gaaagaatga acagatatat gaatacagct
    32521 gattttgatt tccacttgcc agaggaattg attgcccaaa cgccccttga aaaacgtgat
    32581 gcctccaaac tcctcatcgt caaccgtgag acaggagaaa tgcaagataa acacttccac
    32641 tctattatta atatgctgga acctggtgat gcccttgtca tgaacgacac ccgagttctc
    32701 cctgcccgcc tctatggtca aaaagtggag acaggaggtc atgtggaact tctcctcctt
    32761 aagaacacta gtggagacga gtgggaagtt ctggctaaac ctgccaaacg cctcaaggtc
    32821 ggtactcgta tcagctttgg tgatggccgc ctcagcgctg tcgttacaga agaattgacc
    32881 cacgggggac gcattgtccg ctttgaatac caaggaattt tcctagaagt cttggaaagt
    32941 ctgggagaaa tgcctctgcc accttatatc cacgaaaaat tagatgaccg tgaacgttat
    33001 caaaccgtct acgccaagga aagcggctct gctgcagcac cgactgctgg tcttcacttc
    33061 accaaagaac tgctggcaga aatccaagct aagggtgttc atctagtcta tctgactctc
    33121 catgtcggac tcggaacctt tagacctgtt tctgtggata atctggacga acacgaaatg
    33181 cactcagagt tctatcaact ttctgaggaa gctgctgcca cccttcgctc tgtcaaaaaa
    33241 aatggtggtc gtgtcatcgc tgtcggaacc acttctatcc gcaccttgga aactattggt
    33301 tccaagtttg atgggcaaat ccaagcagat tctggttgga ccaatatctt tatcaaacct
    33361 gggtatgagt ggaaggtcgt ggatgccttc tcaaccaact tccacctgcc aaaatcaact
    33421 ctggtcatgt tggtttctgc ctttgcaggc cgtgaattag tcttagatgc ctaccaccat
    33481 tccatccaag aacactaccg cttcttcagt tttggtgacg ctatgtttat ttattgagaa
    33541 agaatttctc taaatcttct aataccaata aatcgctaag atattatttc aaagaacatc
    33601 tacaattgaa actctagcta gctgtagaag aggcctagta cattgaaatt aaaatgcttc
    33661 cccctagctt cgaaaatatt gccatagatt gcgttgactc tccaaattga ttcatctata
    33721 ttttatttca gcttcctata ctttcttcgc tgtttgtaaa tcaaaatgca agacacatga
    33781 gtagcaccat atttgttact cttatctgtc ctctcaagag actattatga gttatttcag
    33841 aatcattcac tactttgacc ctgactctcc ttagtctcaa aatcaaagac ttatactctt
    33901 caaaaatctc ttcaaaccgc gtcaacgtca ccttggatta tatatgtgac tgactttgtc
    33961 agttctatct acaacctcaa agcagtactt tgagcaacct gcgactagtt ttctagtttg
    34021 ctctttgatt ttcattgagt attaaacaaa aagtgaacaa atctgaattc taatgtacag
    34081 aagactaggc ttgttcactt ttttatagtc gctataagat gaccttatct atagcttttt
    34141 atatataatt atatattcag acatactatt atcaattttg tcgcagggag gaatctgtta
    34201 acgcacccat tcaccattat cattgactct atagccatct atacttgtat tgaccgctaa
    34261 ctcacccgat gtatttacat aataccattt accaccaact tggaaccatt gattgacttt
    34321 catagaaccg ttgctgttga ggtagtacca tgaaccatta acttgtaccc aacctgttgc
    34381 catggaacca tcagtattat aaaaatacca cataccattt tcttgtttcc agcctgttgt
    34441 tggagcaact gctttagctg gttctactgc tacatctgtt ccttggttag atgtaacaga
    34501 tacaggatac gaaggaatag atgattgctc aggaacaaca actttttcag gttctctcgt
    34561 ccctctcctt atacgtcttt ttaccatctc tttagtaatt tgacgagaag tagtttcttc
    34621 aattgttcca tcacgttcat ctacagcata gattgtagta agagtaattt taccaatttc
    34681 tcctacttct tgacctttat caagagttgg gtcatcgaga tattctgttt cgattggaat
    34741 ttcttggaca ataacttggg gcttggttcc ttttttaaca actcttgttt gagagtcttc
    34801 tttttgactt aaagtactct cagttacttg tccactcttt ccatctacat cataagttat
    34861 cgttgtaact gttttcccat tctttcctag agtaatctct tgctcctgtc ctgcagaaag
    34921 gtcattgtct gcttcatatt tagtagcaca tggaacaaga acttcttcaa ccttgctttt
    34981 agctggaact ttgataactg tatccgtggc ttcttttcta tcaacagtaa ccttttcggt
    35041 aacatgacca gtctctggat taacatcgta ggtccttgtc gtggttacat agccatcctc
    35101 tccgtcaatt gtaacaggat tttcactacg gtattttgtt tcatcttttt caaaacgaat
    35161 tcgcgtactt gaaattttct tggttactac cttaggttta gtcgctactt ttacaataat
    35221 atccccattg tcagcgtcat catactctat tccctcttct ttatctctag tatcatctct
    35281 gacatattga atcccatcag cagcatgagc aaaacttgta ttcagattcc tcctaaaaat
    35341 aaagttagcc cgattaccgc agaaccaaaa atctttccga gtttacgtat tgcatagcgc
    35401 ttattagtat tagattttgc cattacatcc tacttctagt atagcatctt ttctatcaaa
    35461 cgttaaacaa tatactttat atataaaata gacttagaat gatatattta ctattgaact
    35521 aacactttaa ctatatcgta atcaatctca tatataaagg attgcagaca tctgatctaa
    35581 atacatgcta atatatttag atacaaacat tccaacttga taattttcac tcatctttca
    35641 tcattcctta cacaacgatg cagtataaat agaatagttt tctcatcaga atgagactat
    35701 tttaatatta gataatttga tagaaaaaac ataaataaaa ttggttgaat ttaattccct
    35761 aactcgatag aggattctat tttaaattta acaacagcta ggattacact ataaaaagta
    35821 cattaccacc tgttcggctg gagaatctag tcgattagct ccctcttagt tacaagctta
    35881 aagcgatttt ttaactaata ctaaaccaga ttaaagaagg aactagaaca tctgtcttgt
    35941 actaatcaat atgctatttt aaaattgcaa ataaacttgg aatgctaatt attatattta
    36001 caataaatag ttgacttcga tagaaacaga aaatagaatt caacattctt ccctacttat
    36061 accataataa ataagatccg caagatagcc ttttctctct acaccattaa caatggtttg
    36121 tagataggac attccagcct tttccatgac acgacctgaa gctgggttga gactggcata
    36181 acgtgctctg accttttgaa aacctgcttg agtaaaacaa aagtccaaga cagctttcaa
    36241 ggcctctgtc atcataccat gtccccagta agccttgcct agcacatagc cgatttcaca
    36301 gcttaaatca gcctcgtcta tcttaacgat gctgatatct cctatcactt gctctgggtt
    36361 ttcttttaga caaatggccc atttgtaata gttgagatta gtataggaag caacccaatt
    36421 gcgaatcgag tttcgagtga tttcgacatc aggatgggga tcccaggtaa cataggtcag
    36481 attctcagcg gatgaagccc aattttgaaa catggcttct gcatcactct ccacaaatct
    36541 tcttaaaatc aaacgttctg tctgtaatat ttgcgtacca atagatttca tgatgctacc
    36601 tcacttcctt atttctatgc tcgtagtaaa aaggctcaac tcagtaacag ctagaaaacg
    36661 agtttgtctt ctaatttctt gacgcagtcg ctgcctggtt tgaaatgcga tctagcaagc
    36721 tttttcaaac ctagtcatcg ttgcaggggt aagacgatga aatcgaactc ttcgagttac
    36781 cgaatctgcc tcattttctt atttctaaac tcgaggttca agatcccccg gaccttctct
    36841 cactttctta tttcaagatg agaggctgaa aacctccagt ggaggttttt cttgcttttt
    36901 aatttcaggg caagaagcta aaaaggtccc ccggaccttt ttactcccaa aagtcatcaa
    36961 atacggtgat gggtaagtgg cgtttgtgtt ggcctttgtg ccaccagttt tcaatggtcg
    37021 cttgagcttc tgggctgatt gttttgcctt ctaggtagtc gtcaatctct gcgtaggtga
    37081 ctccaagtgc gacttcgtca gctaggcctg gtttatcttc ttctaggtct gccgttggga
    37141 ttttttcata aagggctggc tctgcgccaa gtttctgcaa gagctgtttt ccttggcgtt
    37201 tattgaggcg gtaaagaggg agaatatccg caccgccgtc accaaacttg gtaaagaaac
    37261 ctgtgatatt ttctgcggcg tggtctgttc caatgaccgc tccgctatgg gaaccagcaa
    37321 gggcatactg agcaatcata cggcaacgtg ccttgatatt ccccttgttg aagtctgaaa
    37381 caggactacc tgtcgcttca actgcagctg tcatggcatc agctgattcc ttgatattca
    37441 caaccaagct gacatctggc tggatgaagg ctagggcttt ttgagcatct gcttcatcag
    37501 cttgcactcc gtatggcagg cggacagcga taaatttgta gctatcgtct cccgtttcag
    37561 ctcgcagttc ttccatagct aattgcgcca aacgtcctgc caaggttgag tcttgtcccc
    37621 cagaaatccc tagtacaaag gtttttagga agggatgttt tttcagatat ctttttaaga
    37681 aatcaataga acgacggatt tcttcctggg catcaatcac tggtttgaca cccagctctt
    37741 ggataatcgt ttcttgcaaa ctcattcttc ttctccttca ccaagggctt ccttgcgcat
    37801 cttatcaatc aagtccatct tatcttgcca tacgtcacgc gccaaatcca ctggatagtg
    37861 ctgcggattg agcacacgct tatactcatc ccacaacttg tcaaattcct tacgggcata
    37921 atcctgaatg tcagtcaaac taggcaagtt gtaaactaat attccttctt tgaagatatc
    37981 caccaagaga ggaacggcat caaaattacg aaccgtcttc ttgatgtatg tataggtcgg
    38041 atggaacatc ttgatttctg tcatgtcgct aatatccaca ccatcataag tgatgtagtc
    38101 accttctgac ttgccttttt cacgactggt aatgcgccac acctgcttct tacctggcgt
    38161 cgacactttt tccgcattat tagacagctt aatcgtattg cgcatctggc cgttttcatc
    38221 ttcgattgca acaatcttgt aaaccgcccc aagagccggc tggtcatagg ctgtaatcag
    38281 cttggtaccc acaccccaga catcaatctt ggccttttgc atcttgaggt taaggatggt
    38341 attttcatct agatcattag aagcataaat cttagcctct ggaaatccag cctcgtccag
    38401 ttgctgacgg actttcttag aaatgtaggc aatatcccca gagtcaatcc gcacacccat
    38461 aaagttaatc tgatcaccca gctcacgcgc cacctgaatg gcagctggta caccgatgcg
    38521 aagggtatca taggtatcca caagaaagac acaatttttg tgggtcgcag cgtaagcctt
    38581 gaaagcctca tagtcattgc cataaacctg taccaaggca tgggcatggg ttcccaaaac
    38641 aggaatgtca aagagcttac ccgcacgcac gttgctggtt ccattggcgc caccaatcac
    38701 cgctgcgcgt gttccccaga tggccgcatc catttcttga gcccgacgtg tcccaaactc
    38761 catcaagggt tcatcttcga taaccaaacg aatacgagct gccttcgtcg ccaccaaggt
    38821 ctggtagttg acgatgttca aaagagccgt ttcgaccaac tgacattggg ctagaggtcc
    38881 ttccacctgc acaatcggtt cattagcaaa aaccaaatcc ccttcttggg cagaacgaac
    38941 ggtcaactcc aacttgaaat tgcgaaggta atccaagaac gccccatgat aaccaagcga
    39001 ctccaaatag gctatatcac tatctgaaaa acgcaagtct tcaagatagt tcacaattct
    39061 ttccaaacct gcaaaaaccg catagccgtt cttaaaaggc tgttggcgga aatacacctc
    39121 aaagaccgcc ttcttattgt aaatcccttg atcaaagtaa acctgcatca tgttgatctg
    39181 gtacaagtcc gtgtgcaatg tcaaactatc atctggatac atacttttcc tacttcctta
    39241 gctagaaacc catgaaaatt ttcaagaact ttcatgtatt ccaataaatt agtactatta
    39301 tatcacattt tagctggatt gagaaaagag taacaagcta ttctccactc tccaattcat
    39361 ccatatcttg ttcaaatttt ttctgagccc attcgccata gctcttaaga ccaagattgc
    39421 caataaagac ccacggaagg taaatgacat aagtaatgac ccaagcagac aggtatttaa
    39481 aattcaaagg attgtgctga taaatttcta tgttgaattg ataattctgc aacatcaaaa
    39541 gagccgtaat agccaaggtt aggaaaaaac aacccaaaat cgtaaaatga aaacgactat
    39601 agtaggtcac tcccagataa cgggcacgat tgaaaaagta aaatgtccct atgatgataa
    39661 cgattagcag catattagaa ttaaaaaggc ttggtgctaa tactgaaatg atataagata
    39721 ggagcgacaa agcaatgcag atatagaaac tttcagagcc cgctttattg aacagttgtt
    39781 cttctctttc gtctagtaat tgataataat aaaatctatt tttcatcttc ttcctcccaa
    39841 aatagttggt ctagggtttt ccctaaacat ctgcaaatag actggcagag cgagagactg
    39901 ggattgtatt ttcccgcctc tatcaaacca atagtctggc gtgtcacccc gacagcctct
    39961 gccagttgac cttgtgttaa atcacgctct acccgagcta attttaattt taaattttta
    40021 gccaccttcg tcctccttat agttttaata ctcatctact cttaaaaaat ccaaaaccaa
    40081 cacaagctat cagctattta ttataacccc attaatttgc actccagtat tatcttcagc
    40141 cgaaaatcag tattttaggt tgtttgaaat aaacttccta gtttactctt ttatttttat
    40201 ttagtattag ctttagtagg atcttttaaa cgagttttta ttgcttatat ttcttgtt
//
LOCUS       DAVKMO010000012        40029 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVKMO010000012 DAVKMO010000000
VERSION     DAVKMO010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40029
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.012"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..734
                     /locus_tag="VW361_000748"
                     /pseudo
     CDS             1..734
                     /locus_tag="VW361_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(850..1653)
                     /locus_tag="VW361_000749"
     CDS             complement(850..1653)
                     /locus_tag="VW361_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU9743841.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1930..2685)
                     /locus_tag="VW361_000750"
     CDS             complement(1930..2685)
                     /locus_tag="VW361_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HEU9743842.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2755..5406)
                     /locus_tag="VW361_000751"
     CDS             complement(2755..5406)
                     /locus_tag="VW361_000751"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU9743843.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRVLEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNDLAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDVTVARIDEMKKLVK"
     gene            complement(5399..5977)
                     /locus_tag="VW361_000752"
     CDS             complement(5399..5977)
                     /locus_tag="VW361_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9743844.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5977..6537)
                     /locus_tag="VW361_000753"
     CDS             complement(5977..6537)
                     /locus_tag="VW361_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9743845.1"
                     /translation="MARTELSDKIETERLVLRVRTVADAEDIHAYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIAGSVDFNHRHEDDVLEIGY
                     TLPPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDVQGNRCDSLIYGLLKSEWEVI"
     gene            complement(6524..6973)
                     /locus_tag="VW361_000754"
     CDS             complement(6524..6973)
                     /locus_tag="VW361_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HEU9743846.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQISILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPEFLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7385..7780)
                     /locus_tag="VW361_000755"
     CDS             complement(7385..7780)
                     /locus_tag="VW361_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU9743847.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7876..8130)
                     /locus_tag="VW361_000756"
     CDS             complement(7876..8130)
                     /locus_tag="VW361_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU9743848.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(8140..9474)
                     /locus_tag="VW361_000757"
     CDS             complement(8140..9474)
                     /locus_tag="VW361_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU9743849.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYEYMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9474..9707)
                     /locus_tag="VW361_000758"
     CDS             complement(9474..9707)
                     /locus_tag="VW361_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU9743850.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            9738..9812
                     /locus_tag="VW361_000759"
                     /pseudo
     CDS             9738..9812
                     /locus_tag="VW361_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10169..10351)
                     /locus_tag="VW361_000760"
     CDS             complement(10169..10351)
                     /locus_tag="VW361_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743851.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(10353..11132)
                     /locus_tag="VW361_000761"
     CDS             complement(10353..11132)
                     /locus_tag="VW361_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743852.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            complement(11411..11761)
                     /gene="rbfA"
                     /locus_tag="VW361_000762"
     CDS             complement(11411..11761)
                     /gene="rbfA"
                     /locus_tag="VW361_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU9743853.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(12012..14804)
                     /gene="infB"
                     /locus_tag="VW361_000763"
     CDS             complement(12012..14804)
                     /gene="infB"
                     /locus_tag="VW361_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU9743854.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            complement(14821..15120)
                     /locus_tag="VW361_000764"
     CDS             complement(14821..15120)
                     /locus_tag="VW361_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU9743855.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            complement(15113..15406)
                     /locus_tag="VW361_000765"
     CDS             complement(15113..15406)
                     /locus_tag="VW361_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU9743856.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            complement(15428..16564)
                     /gene="nusA"
                     /locus_tag="VW361_000766"
     CDS             complement(15428..16564)
                     /gene="nusA"
                     /locus_tag="VW361_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU9743857.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            complement(16608..17087)
                     /gene="rimP"
                     /locus_tag="VW361_000767"
     CDS             complement(16608..17087)
                     /gene="rimP"
                     /locus_tag="VW361_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU9743858.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            complement(17213..17848)
                     /gene="trmB"
                     /locus_tag="VW361_000768"
     CDS             complement(17213..17848)
                     /gene="trmB"
                     /locus_tag="VW361_000768"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU9743859.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            complement(17845..18639)
                     /locus_tag="VW361_000769"
     CDS             complement(17845..18639)
                     /locus_tag="VW361_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU9743860.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            complement(18801..19412)
                     /locus_tag="VW361_000770"
     CDS             complement(18801..19412)
                     /locus_tag="VW361_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9743861.1"
                     /translation="MEFFDKFHALCFGFLVLIIVIIVPYTINHGDFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGLAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            complement(19563..19796)
                     /locus_tag="VW361_000771"
     CDS             complement(19563..19796)
                     /locus_tag="VW361_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743862.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            complement(19838..20527)
                     /locus_tag="VW361_000772"
     CDS             complement(19838..20527)
                     /locus_tag="VW361_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9743863.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            complement(20559..20792)
                     /locus_tag="VW361_000773"
     CDS             complement(20559..20792)
                     /locus_tag="VW361_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family peptide pheromone/bacteriocin"
                     /protein_id="HEU9743864.1"
                     /translation="MDTKMMSQFSVMDNEMLVRTEDGDVSDIYRGYANQRSPFASYPS
                     ILKNSGPFPVSGYCLRGYHDRGYIGAGFHLCGI"
     gene            complement(21036..21239)
                     /gene="blpN"
                     /locus_tag="VW361_000774"
     CDS             complement(21036..21239)
                     /gene="blpN"
                     /locus_tag="VW361_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU9743865.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(21255..21485)
                     /locus_tag="VW361_000775"
     CDS             complement(21255..21485)
                     /locus_tag="VW361_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU9743866.1"
                     /translation="MNTKMMSQFSVMDNEMLDRIEGGIFGVDDALFWAGLGTAICAAS
                     GVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            21775..22362
                     /locus_tag="VW361_000776"
     CDS             21775..22362
                     /locus_tag="VW361_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU9743867.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            22355..23932
                     /locus_tag="VW361_000777"
                     /pseudo
     CDS             22355..23932
                     /locus_tag="VW361_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            23943..25304
                     /locus_tag="VW361_000778"
     CDS             23943..25304
                     /locus_tag="VW361_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU9743868.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEITPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLETTTDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLSNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLGNNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            25361..25516
                     /gene="blpC"
                     /locus_tag="VW361_000779"
     CDS             25361..25516
                     /gene="blpC"
                     /locus_tag="VW361_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU9743869.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(25561..26901)
                     /locus_tag="VW361_000780"
     CDS             complement(25561..26901)
                     /locus_tag="VW361_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9743870.1"
                     /translation="MYIFWIILYTLITNGLEIVIFFKVDGIGLTFERIFKAFLLKILL
                     AFVFVMIGYMIGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYGLFPMILVNLFYRG
                     VSYFVLPFLGQEQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(26914..27651)
                     /locus_tag="VW361_000781"
     CDS             complement(26914..27651)
                     /locus_tag="VW361_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9743871.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIREQDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(27656..27994)
                     /locus_tag="VW361_000782"
     CDS             complement(27656..27994)
                     /locus_tag="VW361_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9743872.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVRYARRRYRE
                     IRQKWLKEGE"
     gene            28269..28598
                     /locus_tag="VW361_000783"
     CDS             28269..28598
                     /locus_tag="VW361_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU9743873.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(28766..29815)
                     /locus_tag="VW361_000784"
     CDS             complement(28766..29815)
                     /locus_tag="VW361_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9743874.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(29812..30543)
                     /locus_tag="VW361_000785"
     CDS             complement(29812..30543)
                     /locus_tag="VW361_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743875.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            30611..31021
                     /locus_tag="VW361_000786"
     CDS             30611..31021
                     /locus_tag="VW361_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU9743876.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            31031..31318
                     /locus_tag="VW361_000787"
     CDS             31031..31318
                     /locus_tag="VW361_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743877.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            31480..31719
                     /locus_tag="VW361_000788"
     CDS             31480..31719
                     /locus_tag="VW361_000788"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743878.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(32041..33177)
                     /gene="dnaJ"
                     /locus_tag="VW361_000789"
     CDS             complement(32041..33177)
                     /gene="dnaJ"
                     /locus_tag="VW361_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU9743879.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVYGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(33382..33636)
                     /locus_tag="VW361_000790"
     CDS             complement(33382..33636)
                     /locus_tag="VW361_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743880.1"
                     /translation="MLVTVERNGNVIYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHIC
                     QELHLYKTQDPHYNKFEFDLAKRSLKITTRDNTTIFISNE"
     gene            complement(33748..35571)
                     /gene="dnaK"
                     /locus_tag="VW361_000791"
     CDS             complement(33748..35571)
                     /gene="dnaK"
                     /locus_tag="VW361_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU9743881.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(36001..36525)
                     /gene="grpE"
                     /locus_tag="VW361_000792"
     CDS             complement(36001..36525)
                     /gene="grpE"
                     /locus_tag="VW361_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU9743882.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSKLDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(36552..37586)
                     /gene="hrcA"
                     /locus_tag="VW361_000793"
     CDS             complement(36552..37586)
                     /gene="hrcA"
                     /locus_tag="VW361_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU9743883.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(37750..38259)
                     /locus_tag="VW361_000794"
     CDS             complement(37750..38259)
                     /locus_tag="VW361_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU9743884.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            38867..>40029
                     /locus_tag="VW361_000795"
     CDS             38867..>40029
                     /locus_tag="VW361_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9743885.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDTNG"
BASE COUNT        11969 a         8794 c         7360 g        11906 t
ORIGIN      
        1 cagataagga ccaagagctt aaagctgaaa ttcaatccat ctttatcgaa cacaagggaa
       61 attatgctta tcgctgtatt catttagaac taagaaatcg tgcttatctg gtaaatcata
      121 aaagagttca aggcttgata aaagtactca atttacaagc taaaatgcga cagaaacgaa
      181 aataaaggag acgttggtaa gaaggcagag aatctcattc aaggccaatt tgaaggctct
      241 aaaacaatgg aaaagtgcta cacagatgtg acagaatttg ccattccagc aagtactcaa
      301 aagctttact tatcaccagt tttagatggc tttaacagcg aaattatcgc ctataatctt
      361 tcaacttcac ccaacttaga acaagtacaa acaatgttgg aacaggcatt cacagagaag
      421 cactacgaga atacgattct ccatagtgac caaggctggc aataccgaca cgattcttat
      481 catcggttcc taagagtaag ggaattcaag catctatgtc acgcaaggga aacagccaag
      541 acaacggtat gatggagtcc ttctttggga ttctgaaatc ggaaatgttt tacggttatg
      601 agaagtcgtt tcagtcgctt aagcaattgg aacaagctat tgtagactat attgattatt
      661 acaacaacaa gagaattaag gtaaaactaa aaggacttag tcctgtgcag tacagaacta
      721 aatccttcgg ataaattatt tgtctaactt tttggggtca gtacacctaa aactttgatg
      781 atatacgttt tcttgtgaga atatttactt catttttgcc taaaattcaa tgtttactca
      841 gtatttggat tatgaaaaat cgaggtctaa atctagatac attttttctg aagacaaatc
      901 attttgacca ccgagcaaga gattttcaaa aaaagctgtt aaaaactcag aacgtcgctg
      961 taaaatcttt gcattatcta ataccaaggc atcacgaaaa tatttggaat gttgctgaaa
     1021 tggtgtatta tcaatatcaa aaccaaactc acgaagatac tgaatcaaaa agaccgttac
     1081 tgtccgagtg tttccttcgc gaaatggatg aatctgccag attcctgaaa taaaatgctg
     1141 gatttgttta accacatccg cctgagttag tgtcgcatat gcaacttgtt tttcctgatt
     1201 aaaatcataa tctaaggtca tttgaatcat ggagtaatca gagtacacaa cactttcacc
     1261 attcaaaaca ggttcattct ttgtgatatt ggtctgacga aattgcccca ccggaataga
     1321 gggttcaaat atatcttgaa acaactcctt atgaatagca agtaaggtcg caggactaaa
     1381 gctaaagcct cttcgagaca atagttctac aatacgtaga gaaaccaagt ctgcctcttc
     1441 cgtacttgca tcaatagtat ggtgataagc cgttgcatcc tcataaacct gctcataagt
     1501 cagttctccc cgggactgtt tctcagccaa agattccata tacgctgatg gcactagatt
     1561 gtcaactttc tgcagaccaa aacctatccg ccataaatca cgcttcgctt cataagacaa
     1621 gtttggattg tcaatgttgt aagttggttg catagaaata tcctttcaat tgtttttctt
     1681 cattaccagt aaatcacgaa attggttgga aactggctta aactataaaa agtcctcaca
     1741 ataggttcta tgatatatat atatacttca tgtaaataat aaaagagtta taatcagcac
     1801 tactgataaa ttcaataccg atttcgccat cttaaaactt agtcaaacga ataccgttga
     1861 tttccagttc attaagtcgt tgacctgtca agacttctcg ttccttcaac tggaaaagtt
     1921 aagggggaac taatacaaat cctctacgct tctatattca atgatttcat ttttgataat
     1981 attcttttta aactcaaaat gttttaaagg attatcgatt aacactaact ttggaatatc
     2041 atctagattt gtgaccaagg ataaaataaa atccgattga aactccttga ctttttcaaa
     2101 ttcttttgca gttaaacgca cacgcccctt agattttcgg atacctttta cttcggcaag
     2161 gtaagaatac tcttggacat ctacctgaaa gtcatatcca tcaccataaa gacgggcatc
     2221 ggttaactgt ccaccttgga atttttcttc tttatcaaaa tgaaggataa aataattctc
     2281 agcctccatt cccgtttcct gtagacgttt gaatttagtt cgaactattg gtttttcaac
     2341 gatggttatg cctgttttct tcccttcact ggcaagtaac attttaacta tttcagcata
     2401 actatgaaca tcttcatttc caaacatcat atcaattaaa tctttacgaa aacgataaac
     2461 ttcagctttc tgccaccaac cttttcgatt attgtcaaaa taaggatcaa ataaatccat
     2521 tctatttttt acaactccag ttgtttcagc aattcccaga gaaaccacat agcgataaaa
     2581 ctccgacttg ctagagcatt gaaattcttt tataaaaagc ttgtcaaact tggcaagacc
     2641 gtagccaatt aaatttaaca attcataatg agggtgtttg gacatcactt tctccatcaa
     2701 tagatattga tttcattata ccaaaaaaca cggctcatca ccgtgtttct gtgtttattt
     2761 caccaacttc ttcatctcat caatacgtgc tacggtcaca tcatacttgg cttggtagtc
     2821 ggcttgtttg tctttttctt tttggacaac ttctggttta gcgttggcga cgaagcgttc
     2881 gttgctgagt tttttgccaa ccatgtcgag ttctttctgc catttggcaa gttctttttc
     2941 cagacgtgcc aattcttctt cgacattcaa gaggtctacc agtggcaaga agatttcggc
     3001 tcctgtaata acgcttgaca tagccagttc aggtgcaggg atggttgatg cgatttccaa
     3061 gtgttctgga tttgtaaagc gtttgatgta gttgacattg ctgttaaaga aggcttccaa
     3121 gtcactatcg ctagtcttaa caaggatggt gataggtttg cttggtgcta catttacttc
     3181 cgcacgcgca ttacgaacgg cacggatcaa gtctttgaga ctttccacac cagtgtgggc
     3241 agcaaggtcc tcaaaggctg ggttgacagt tgggtatgct gctgtcacga tagagccttc
     3301 agcgtactga ccaaagattt cttctgtcac gaacggcatt attgagtgaa ggagacgaag
     3361 gattttatcc agcgtataga ggagaacaga tcgagtaatt accttatcgt cttcattgtc
     3421 gctgtaaaga acttccttgg tcaactcaac ataccagttg gcaaattctt cccaaatgaa
     3481 gttgtaaagg atatgaccag ccacaccaaa ctcgaactta tcaaagtttt cagtaacttt
     3541 tgcaatggtt tcgttgagat tgtggagaat ccagcggtcc gtcacattac cagcctcacc
     3601 tgttgcaact tttgtgacat tgtcatgcgc cacatccagc gtcaaacctc cattgttcat
     3661 gaggatatag cgagaaatgt tccaaatctt gttaataaag ttccatgaag catccatttt
     3721 ctcataagag aaacgcacgt cttgtcctgg cgcagaaccg tttgaaagga accatcgaag
     3781 ggcatcggca ccgtatttct cgataacatc cattgggtca atcccgttac cgagagactt
     3841 agacatcttg cgtccttgct cgtcacgaat gagaccgtgg ataaggacgt tttggaatgg
     3901 ttgacggcct gtgaattcca atgactggaa gatcatacga gacacccaga agaagatgat
     3961 gtcgtaacct gttaccaagg ttgaagttgg gaaataacgt ttaaagtctt ctgagtcgac
     4021 ttcaggccag cccatggttg aaaatggcca gagggcagaa ctgaaccaag tatccaagac
     4081 gtcttcgtcc tgagtccatc cgtcaccttc tggagcttct tcgccgacat acatttcacc
     4141 atcagcattg taccaggcag ggatttggtg accccaccag agctgacgag agataaccca
     4201 gtcgtggaca ttttccatcc attgaaggaa ggtatcgttg aaacgaggtg ggtagaattc
     4261 gaccttgtcc tctgtgtctt ggttggcaat ggcgttctta gccaattggt ccatcttgac
     4321 gaaccattga gtagacaagc gaggttcaac cacaacacct gtacgctctg agtgaccaac
     4381 actgtggaca cgtttttcga ttttgacgag ggcaccgatt tcttccaact tagcaacgac
     4441 tgccttacga gcttcaaaac ggtccatgcc tgaaaattca aaggccaagt cattcatggt
     4501 tccgtcgtcg ttcatgacgt tgacttgtgg caagttatga cgttggccaa ccaagaagtc
     4561 atttggatcg tgggcaggtg tgattttcac gacaccagta ccaaactcag gatctgcgtg
     4621 ctcatctcca acgattggga tgagtttatt agcgattgga aggatgacat ttttaccaat
     4681 caagtccttg tagcgcgggt cttctgggtt gaccgcaacc gcaacgtccc caaacatggt
     4741 ctcaggacga gttgtagcaa cttcaaggac gcgtgaacca tcttccagca tgtaattcat
     4801 gtggtagaag gcaccttcca catccttgtg aatcacctca atatcagaaa gggctgtgcg
     4861 agctgctggg tcccagttga tgataaactc accacggtag atccagcctt tcttgtaaag
     4921 gtccacaaag accttacgaa cagcttttga caaaccttcg tcaagagtga aacgctcacg
     4981 agaatagtct acagagagcc ccatcttgcc ccattgttcc ttgatagtag tggcatattc
     5041 gtctttccat tcccagactt tcgtcaagaa agactcacga ccaaggtcat agcgggaaat
     5101 gccctcacca cgcaagcgct cctctacctt agcctgagtg gcaatccctg cgtggtccat
     5161 cccaggaagc caaagggtat caaaaccttg catgcgtttt tgacggatga taatatcttg
     5221 caaagttgta tcccaagcgt gaccaaggtg aagtttacct gtaacgtttg gtggtggaat
     5281 aacgattgaa taaggcttag ccttttgatc gcctgaaggc ttgaaaacat cagcatcaag
     5341 ccatttttgg taacgaccag cctcaacctc ggctggattg tatttagatg aaagttcttt
     5401 agacatgtgt gtgtcctttc tctattttgt ttattttatt ttgaatctgc ttagcagctt
     5461 cttctgcaga caaattcgta ttatttattt taaagtagtg gtgcaactca ttcggttgat
     5521 attgggaatt taattgaagt gtttcagcgg tctctaaaat ttctctttca gatacctcaa
     5581 tatgtcgttt taagggtttg tgctttaatc gattctccgt tcgatttcga cgtatgcact
     5641 cttcaagact tgtttccaac tcaacaaaaa gaatctcttg atgataatca tccaacaaat
     5701 tctgaatttg ctttaaatat atcagatgat actgatttga aaaatcaatt acatctgtta
     5761 aaattactga tcgctgattt cttgcacttg ctccaaggaa tgaaaaagtg attccacgaa
     5821 caaattccca catttcctct gtatagtcct gatagatttc tagtgcaaaa tcaatggctt
     5881 gatggttata aaatagggta gcatccgtca gtcgagataa ttcttgacca atggtcattt
     5941 ttcctgatgc tggagcacca atgatgaaaa gatgcatcaa atcacctccc actcgctctt
     6001 cagcaagcca tatatcagac tgtcacagcg gtttccttga acatcctttc ggtctcggat
     6061 gcgagcttcg agggtaaagc caagcttttc cgcgactcgt tgactttgaa ggttatatcc
     6121 aaagcaagtt agttcaatct tgtgaagacc caaatcttta aaggctaagt caatcaaggc
     6181 acgcgcagct tctggcacat aacctcgccc ccaatagtct gggggtaagg tatagccgat
     6241 ttccagcaca tcatcttcat ggcgatggtt gaaatcgaca gagccagcga tcttatccgt
     6301 tcctttgacg acaatcccgt agcctgctgg gagattttcc ttttgattac gctccggaag
     6361 aatgtgctcc agataataaa tctcatcttc caaggtcttg actggaggaa aacctgctgg
     6421 ataggcgacc tctggcaaac tagcgtaggc atggatatcc tcagcatccg ccacagtacg
     6481 gactcgtaaa acgagacgtt ctgtttcgat tttatctgac agctcagttc ttgccatcct
     6541 tcttcctcgc ttttttgatg aaactgccct tcatatctac acgcttgtcc agatagcgat
     6601 aaacgcgctg atatccatct cccatgaaat aggttggggc aaacagttga tttttaaaat
     6661 gtcccttttc atccaggaat tctggggcaa caagtcgctc aagaatcttg gcaaagatgt
     6721 ggcaaatacc gtcttcctca acaatcctat ctacccgaca atctaaaaca agtggacagg
     6781 cgtctaaaat agaaatctga gttcgttcag aaatttcata atgcactccc aaacgttcca
     6841 atttctcctg atgactgata aaaccagcct gctccatcgc aagcatagaa gtttcatcag
     6901 aaatattcac agtaaatttt tgatactgtt tgatctgctc tgcggcattc tctctcgcaa
     6961 cgactccaat cacaacccaa tctcctagac tataagagga actacaggtc gtgatgttat
     7021 agccaaaatt ctaatcttga tatcctaaaa taaaaacagg aaaaccataa tatagtttat
     7081 tagttttaaa tgattgtttt ataacaacct cctttgacta agacacaaaa gaaaagccct
     7141 gccatctaca tgacagggac gaatgtgttt atccgcggta ccacccaatt tcgggccaag
     7201 cccgcatctt tagtctttaa aataaaaaga cagaaatatt tcattttttc agtcattagc
     7261 aaccagtttt gacacatttg tggacttctc agcgccgcca ctttctgtaa aatgtgggat
     7321 tcaaaacacc tctaatggct ctattgtagc aagtttttct cggaaatgca aggctcaaga
     7381 aaaattactt gaacttgatg ccattttctt tcaatttctt gatggtagct gggccgattc
     7441 ctttcaaggc aaggagttct ttttcagtcc agtttttgaa atctgaagca gacttgattc
     7501 cttcatcata gaaagtcttg gcacgatcaa gtggaagtcc acccaagttt gctgcaaaat
     7561 cttctacaga attagctact ttttgagctt gctctttggt agcttctact gcttgttcaa
     7621 cttttttaga aacagcctta ccagctgcgc ttgctgactg ttctgcacgc ttcacgactt
     7681 tttttgtctc atctacaacc ttagtcacag tacttgaaaa ggcacctgcg cgacggaggc
     7741 catttcgtaa ttgtttttta cgattgagtt tctttgacat gataaaatcc tttcaataaa
     7801 aaatccctgc tctgacaagg atttaacata aacattctat caagatttta gtgaaaaatc
     7861 aagaatcttt ctcgtttaat aatttcgctc accaaacaag ccttctggca aatcatggaa
     7921 tcccttgcct actttgaagt tttcaaactt accaagcaag aactgataag catccaaacg
     7981 actctcatag cgaatcatgg catctttggc acgctcgtcc tggtcttctt cgtaaacttt
     8041 ttggctttcc ttgtgcgcca tgtcgttaat catgatttgg gtattgaccc aagcttcaaa
     8101 ttccttcata aattcttgtt cgtaactcat tttttctcct tattctaatc cacgaaaata
     8161 gtccgtatca atctcacggt agggctggat atcctgaaca tactccaaca ctccttggaa
     8221 ttctccgtct tcatcgtgta ctgcagcata ggtgatgtgg acaaacttac ctcgcgactc
     8281 agacttgaac cacatttcat acttgtcttt gcttccctca cgaagtccct tcatgatagc
     8341 cttgaccttg tccaaatact taggcggatg acagagttcg acattgcgcc cgacttggga
     8401 cggcgtccgt ttgaaaatca tctcatcagc tggcgtattg tcattgtaat actggaaaat
     8461 atcttcttta ttgacaaagg taatctccat agggaggtga ttgaggatga gattggcctg
     8521 ctcgactgaa agatagccat taccaaaagc ctgttgacta tggcggtcca gcacagcttc
     8581 cttttcctta ggggtaaagg taatggtaaa atggccttct ggcgtatcta tgacttgttg
     8641 aacttgacct tctgccgtat ctagctgtac aggctcctct gcaatctttt cctcaataaa
     8701 gctctgtcgt tctggcaccc atttctctga cggacggatg atggcatagc cataggcatc
     8761 gctctcctcc gcaatctgaa gccagtcatc ctgagtaaaa gactcaagga gaatcatgag
     8821 gaggatggac tcttccttga aaatcatact ttcaaactct gtcgcaaaag cttcaaaagc
     8881 ttcctttaca ctgctaattg acacttctgg tagtgacttg gctgtcgtta gagctgtttg
     8941 aaagagttcc ctaatctgat catccactcc ccacataact ttgggaggtg aatcgtgtcc
     9001 atagcgctcc atgataggaa agaagagttc ttccttacgt tggtaatgga tgtcaaattg
     9061 acccacaagt cccatctgac gcaccaaacc cttacgcatc tccgccagca tttcctcgtc
     9121 ttccatatac tcataggtat ctaacaatct acgaatgcga atcaaggccg cacggagagc
     9181 cagattttct tctttgaaga cacgaactgg gtgacctgga tgctcagtat ctgaaacttc
     9241 gacacctttg atagcatttt taaaaagatt ggcatggaca tcacagagtt ccataacatc
     9301 ttcaaaggtg acacctgagt ctgagttcat cagctcgtgc tccataaggg aaatctcgat
     9361 ggctgagaca cccgcaaagg tcgcatcaaa gcgctcttga accgactcag gagaggcgcc
     9421 attgtgcaat tctaacaaaa tatcccgtag gacatgaatc cgttcatctg ccattagtct
     9481 aatccaatca cttcgtagcc attcgcttcc agtgtgcgta caatcttgtc cataggagtt
     9541 cctgctagct tagaaccctg tttaagtgat actttacgac caactgtatt gcgcattaag
     9601 ggattggcaa ggggtttaaa acccaactcc actagaattt ccaagacttc tggatgcttg
     9661 tccaccactt ctgcaacagg aattgacaca tcgatgatat tgtccatgac gacctccatt
     9721 gtatgttcta atactcaatg aaaatcaaag agcaaactag gaagctagcc gcaggttgct
     9781 caaaacagtg ctttgaggtt gtggatagaa ctgacgaagt cagctcaaaa caccgttttg
     9841 aggttgtgga tagaactgac gaagtcagta acatatatac tgcaaggtga agctgacgtg
     9901 gtttgaagag attttcgaag agtataaaat gattttactg cttatattat accatatgga
     9961 aagagaataa aaaactagca gtggagttcc tgctagttct ctgcgacttg gattaccatc
    10021 tagataagtt taaagagcca atccaatatc ttaaacacta tcttgtaaaa cagcaattgg
    10081 actgcaaaag agatgatcat ccaaaagaat ttcacaatcc caataatcgg tttgataaaa
    10141 ataatggcaa gaagtcccca gaaaaatttc attttttatc ctctggctta atgagccacc
    10201 gagccgtatc cattagctta tctgcaataa agagttttcc cagaccaaca acgacatggt
    10261 catctttctt tatcgttttc attactttta caccttgcac ggtcaaaaag taattaccat
    10321 aaattttagc tagagttttt atgagtccca tattactctc cttcgatgat ttcagcctct
    10381 tttcggattg tttcaacatc ttcttgatat tgaacttcac tatagttaac tagcttggac
    10441 aattctttct gcaagctttc acccatcggt ttcatagttg caaaggttaa accacctgaa
    10501 atgataccac ccaagatagg aataaatttc cccattcctt tggccagccc tcccttggta
    10561 agattcacac caaatattct taagactttt ttcaaaatag gataccaaag cgtctttgtt
    10621 aaagctttat taggtactgt tttcattacc tgtttggcaa ttgttatacc accagcacgt
    10681 agcaaagcag cagttccatt cacccccaac atgacgccta gataaagcaa aagggtattt
    10741 tgagcatctt cactcaactc atcgcgtgaa gcccaaagat cctcataacc ataaatataa
    10801 cctaattctt gggccaattt cagagagaaa ccataaaatt gagccacatc agctggaatg
    10861 gtaattgcca tagcaagccc tccaggtaat cctgccaaaa cagaagtccc actcgctaat
    10921 aaaacattat ccctaataca ggcattagcc actcgatcta agatttcttg agataagaga
    10981 gacgttggac cttgttccaa taaggtagga atgtcctgtg gacccaattc tttggaaaac
    11041 ttatccacta aaaatttcga acgatcaacc ttaacaacag gtagtttcac cacttgttgc
    11101 aatacttgca tagctaagtc ttgttcagcc atatacaaac tccttatttc ttttttgcac
    11161 cttatcatat tatatttcct acaaaaaaag cattttctaa ttagataaca ttaaaaaata
    11221 cagaacccct tttttatagt gaaatgaaac aagaacagga caaatcgatc aggacagtca
    11281 aatcgatttc taacaatgtt ttagaagtag aggcgtacta ttctagtttc aatatatttt
    11341 aaaagaatat ttttccattt caaattcaac ctattttcct ccaccaaaaa agaggggcaa
    11401 cccctcttct ttagttctta tccagattgc gtagcatctc gtcaatcttg tttccatact
    11461 cgatggactc gtctttgacg aaggtcaaat ctgggatttt gtacaatttc aaattgcgac
    11521 caagttcacg tttgatggta ccagttgctt tttcaagccc gatttgggct ttttggttat
    11581 ccgaagcaag gttactcaaa atggtgtaat aaaccttggc aacagacaag tcacccagca
    11641 tctgaacatc tgtgatggtc acaccttgga cacgtggatc acggactttc ttttgcaaaa
    11701 tctcattgac ttcacgcttg atttccatgc ccacacgatc tgtacggaaa tgatttgcca
    11761 tgatattcct ttctctactt tgaaccaaaa gctaggccag cagacctagc tattttaaac
    11821 ttcttgattt tcagtttaaa ttgaaacgaa gttcaatttg aagtcatctg cttctttcgc
    11881 cgtggtgaaa gtgatggaac tgatttatca gtcccatcac aggggatttt tgagacccta
    11941 ggctcaaaaa taagcaatga aaccatcggt ttgcttgcgt ccctcaccac ctaagaaagg
    12001 agcaaaaaat cttatctctt gatttcttcc atgacatacg cctcaatcac atcatccatc
    12061 ttaatatcat tgtagccgtc gatcatcaat ccaccttcac gaccgtttgt cacttctttc
    12121 acgtcatctt tgtagtgttt caagcttgcg agttcgccat catagataac gacaccatca
    12181 cggataacac ggactttaga gtcacgggca accttaccgt tgataaccat aaatccaccg
    12241 atagttccga ctttagacac cttgaaggtt tcacggataa ccgcttcacc aataactttt
    12301 tcttcaaatt ctggatcaag catccctttc atagcttctt ccatctcttc gataaccttg
    12361 tagataatgc tgtgaagacg gatttccaca tcgtcagctt ctgcttgttg acgagcttgt
    12421 ggtgtagggc gtacgttgaa accaacgata aaggcatttg aagcttcggc aagggtcaca
    12481 tctgattcgt tgatagcacc gaccgctgag tggacgatag tcactttgac accttccacg
    12541 tcaatctttt gaagtgaggc agaaagggct tcaacagaac cttgtacatc ggccttgatg
    12601 ataacattaa cagatttgag ttccccagct ttaagggtat caaagaggtt ttcaaggcta
    12661 acacgttggg tagcttgacg ttgtttcatg agggcacgtt tggcacgctc ttcacctgct
    12721 gcacgcgcag atttttcatc ctcgtaaacg gcaaagtggt cacccgccat cggtgcttcg
    12781 ttcaaacctg tgatagagac tggtgttgat ggtccagcaa ctttaacacg acgaccaagg
    12841 tcgttggtca tagcacggac acgaccgaag gtatttccga caacgattgg gtcttgaaca
    12901 ttcaaggtac cttgttgtac aagaagggtt gcgaccgcac cttttccttt atccaagcgc
    12961 gcttcgataa ccgtaccgat cgcacgaact gttgggtctg ctttgagttc ttggatttca
    13021 gccacaagaa ggactgtttc caacaattct tcgatatttt ggttgaattt agccgagatt
    13081 tcaacaaatt cagaatctcc accccaagcg gttgacatca caccatgctc tgccaattca
    13141 ccgataacgc gttctgggtt agcacctggt ttatcaatct tgttaatagc tacgatgatt
    13201 ggaacgttag ctgcttttga gtggttgatg gcttcaatag tctgaggcat aaccccgtca
    13261 tctgccgcta cgaccaagat cgtaatatcg gtaacagaag caccacgcgc acgcattgat
    13321 gtaaaggccg cgtgtcctgg tgtatcaagg aaggtaatct tcttaccatt ttccacgatt
    13381 tggtaggcac cgatatgctg agtaatacca cctgcttcac ctgtcgcaac acgtgagtta
    13441 cgaagagtat ccaaaagggt tgttttaccg tggtcaacgt gtcccatgat agtaacaact
    13501 ggtggacgct caaccaattc atcttcattg agataaccat cttcgacaaa gaaacgttcg
    13561 atgtcagcat tatccacttc aaccttttgt ttggcttcga taccgtaatc caccatgagg
    13621 agttcaattg tttccccatc caaggattgg ttttgtgtgg ccatgacacc catcatgaaa
    13681 agtttcttaa caatttcagc tggttcacgt ttgatacgtt ttgcgatttc cgcaacggtc
    13741 ataccatctg tatattcaaa ttctgttggc aattcatgga atttacgctc cgtaacaggt
    13801 tttggagtct gattacggtt gttcttgtta ttgccttttt tgttcttttt gttgttattc
    13861 cagttactat tcttttgatt tctcacttga ttttgactac ttcgattctt ttgttgtttt
    13921 ctaggaccat cttcttcatg atcataatcg tcacgatttt tgtctggtcg agcttgtttt
    13981 ttacgacgtg tatccactgc aggttctttt ttctcaggga cgacttcaac cactgcttga
    14041 acttgctgtg cttgttcagc taacttagcc gcttcttcaa agatttcctc tggttccttg
    14101 cgtttgttag cttgagccaa ggcttcttta gcagcctgat actgcttgaa gcgttcctca
    14161 cttgaacgag cgtactctgc attttgctct gcttttaggg ctgctgcacg ggctttaaag
    14221 tcaatacgtg gagccacttg atttgaacgt ttgtcctctt gctgacggcg ctcatttcta
    14281 cgtttttgct gaccttgctg cttcttagct tggtcattaa agcgacgatt gtcgcggttg
    14341 ctttgacctt gttttccacc attacgtccg tcgtttttct gacggtttcc gttttgttgt
    14401 tggtcacggt tattgccctt attttgctta cgtcgttctg cctgctcttt agcacgggct
    14461 tcacgctcag ccttgaaatt acggctttgc ggtttcgctg ctactttttc tgttttcgga
    14521 gcaactggct cagccggttt tgcctcttcc ttagctacag ctggtttagc tggctcagat
    14581 ttttcggctt tcttttctgc acttactttt ggtgctgcag gttttgcttc tactttcgga
    14641 gcagctgcag gcttaaagct ggcagcaatt tttgcagcga cagcttcttc cacacttgat
    14701 gagtggcttt tcacatccaa gcccaactct tttgcacgcg ctacaacttc tttactttct
    14761 tttccaagtt cttttgcgat ttcgtacaat cttttcttag acaaatcatg tcctcctctt
    14821 ctattccata agagacctca ttttctttgt aaatccagca tctgttacag ccaaaacctt
    14881 tctcgatttc ccgactgcta tgcttaattc cagtgttgaa aacacggtta caatttctac
    14941 ttgataataa tgacttttat cttgaatctt cttggtcaga ttgggtccag catcatgagc
    15001 tagaaagacc aacttggcct tgccgtcttg aatggccttg accaccaatt cttcacccga
    15061 tatgatgcgc cctgctcgct gagcaagccc caagagatta cttatctttt gcttattcaa
    15121 gtcccaactc tcttcttttc actttgtgat ccacataagc gatcaactcg tcataaaagc
    15181 tttcttccac ttccatgcta aagctgcggt taaagacctt cttctttttc gcctctaggg
    15241 cttctgcatt gtctagtttg atataagcgc cgcggccatt ggccttgccc gtaggatcaa
    15301 taaagacttg tccttccttg ttcttgacaa tgcggagcaa atcacgctta tcaatcactt
    15361 cgttagacac aacagacttg cgcaaaggga tttttcttgt tttcatcttt ccctcctcta
    15421 gcagctttta ttcttctaca gtatcgtttt ctacttccaa ctctactgaa gcagcgtctt
    15481 ccatggcttc aaattcgcta gcagacttga tatcgatacg gtaaccagtc aagtgagccg
    15541 ccaagcgcac gttttgtcca cgacgaccaa tggcaagaga aagcttgtta tctggaacaa
    15601 ccaccaaggc acgtttgctg tcgttttcat caaagataac ttggtcaacc tcagcaggag
    15661 cgatggcatt gtagataaat tcagctggat ctgctaccca ctcgataaca tcgatatttt
    15721 cttcgattgg taccatgcgg tcatttttag catcgtaacg agctgggtgg aatttgctag
    15781 taatcttctt gatattagca ccaccacgtc caacgattgt accgatagca tccacgtttg
    15841 gattgtggct acgaacagca accttcgtac ggtcacctgc ttcacgagcc acgctcatga
    15901 tttcaacagt tccatcataa acttctggaa tttcttgctc catcaaacgt ttgatcattt
    15961 ctggatggct acggctaaca aagacgttca caccacgagg gttgtcttca accttgtaaa
    16021 cataaacttc gatacgatca tgagaagcaa aaacttctcc aggaatttgg tcttgttttg
    16081 acaattgggc ttcgatgcta ccaaggttga catagataaa gcggttgtca aagcgttcta
    16141 ctgtaccaga catgatttct tgctcatgtt ctttgtaagt attgtaagtg atggcacgtg
    16201 tttgcttgcg cattttttcc atgatggttt gtttggcaga ttgggctgct acacgaccaa
    16261 actcagctgg tgcttcttca aacttgattt tgtctccaag ttcataagct gaattaatag
    16321 caagagcatc tttcaagctg atttccaaac ggctatcaaa tacttcatca acaacttcac
    16381 ggacagtata aactgtaaag tcacctgttt tttcgttgaa gtcaatagct acgctgtctg
    16441 actgaccata gcgtctgcga taagcggaac gaagcgactc tactactgcg tcgatgatat
    16501 cttctttttt gattcccttg tcttcttcca aaatgcggaa ggcctctagc atttctttac
    16561 tcatgttttc ttcacttttg aatcctcaaa agctatcctt tctttttcta taatttaact
    16621 gctaaacgtg cttttgatac taaactgtat ggaatttgga cggttttctt acgcgtcttg
    16681 tccatatatt ccatagtcaa ctcgtcctct tcgaaggcca acaaggttcc ttcaaagacc
    16741 ttttgcttat cgatggcttg gtagagcccg acatggatgt attttccaac cgctccagcg
    16801 acggcatcct tggttttcaa aggacgttcc aaacctggac tggtaatttc taggaaatat
    16861 tgttctggga agggatctgg cttgatggtg tctaggacag gactgatcat ttctgtcaag
    16921 tctgccgtgt cgttcaaggt aattccttcg ggtttatcta caaaaatact gagaatcatg
    16981 tcactgccaa tctttccata ctcgatatcc acgagttcaa aaggagcttc tatgacaggt
    17041 tctacaactt ctctgactaa ttctacgatt gttgcgattg cgtccacctc ctcataagca
    17101 agaggcgaag atatttcccc gcctcacttt tcatattctt attatcagta tagcacgttt
    17161 gccaacctat gtaaagcaaa agcacttgta cagcctaatt ttaggctatc tattaaaatt
    17221 ctgcctcaac tcggtagata acttgcccct tgtttgagaa tttttgctcg tattctgtca
    17281 tgacattgcc ttcaaaatca ctggcatgca aatctaacca gacaccattg agtttcatgc
    17341 catattgaga aaagctcact aaactgtact caaacaagcc acggttatcc gtcttgaaat
    17401 gaatttctcc attttcaggc aagatacgtt tgaaggtatc caaaaaggtc ttgtaggtca
    17461 aacgacgctt ttcatggcgt tttttcggcc atggatctga aaagttcaga tacaagcgat
    17521 caatctcacc gtcttcaaag tagtcagtca agtcagaacc atctacccac aagagcttga
    17581 tgttagacac tccagcttca agcaccttgt ccaaagcgta gctcaaaaca gacttttgaa
    17641 tatcaatccc gatatagttg atgtcagggt tttgcttggc catacctgaa acaaaggcac
    17701 cctttccact tccaacttcc acatgaatgg gattatcatt gccaaacaag tcccgccatt
    17761 ttgccttggc ttccaaggga ttgaggacca catactgggg atttgcctct agtaattctg
    17821 ttgccccttt acgatttcta actctcatct tctctttcca tacttgtctc ggaaatgacg
    17881 caaaccatga atctcccgat tgacattttc taaatcttgg ttcatataat acttggaaat
    17941 ctgactcaaa taagacaatt gaccatacca atacaattta cttaataccg tttgattgta
    18001 cttgtaaccg tagtaggtca accattcctt ccactgatgt tctgaaatat aatggcagag
    18061 catatgggcc acatcaaaca tgcgatcggt caagcgaacc gaatcccaat ctactaaata
    18121 aatcaagcca ctatctgtct caatccaatt actatgtcgt acatctccat ggacaatggt
    18181 cgcatggtcc tctctaaatc ctggaatagt ctgacgtaaa tcagccatca cttcactgat
    18241 aaaatgattt ttacgcaaag catctggagc cgtttcctgc caagactgta gtaaatctac
    18301 aggtgtttcc atggcatagc ccaaacgact caattgtgtc atcaacggac gtgagcgatg
    18361 aagacgggtt aaaatattga cgatttgctt acgattcata tcataggggg tcaatatctt
    18421 gcctgtcaac cattcttgag cacacatatc acgcccatct gccaaacgac gactccataa
    18481 taattgtgga gcaatttgtt ctctagctag accaggtagg attggagagg tgttcatttt
    18541 tacaaagatg cgcttcccat caggatagct acccatataa gccttgccac ttttcccagg
    18601 tatgggagtc agtgttagct cattatcacc caaatccatt tctttcctcc gtataaagtt
    18661 tccttactat tctactagtt tttggcctat tcgtcaacca ctctaacccg attctcaaag
    18721 aaaagcctct ggagtggttt gggttatcat tatagaaaga aaaaggtaag cacaatctcc
    18781 tacttacctt ttcataattt ttataaataa tataggagtg gccaactgtt gtaaaacatg
    18841 tggactagag tagaaaccca taagttttgg ctctttttat aagcaaggcc cagcaacaag
    18901 cccccaagta gataaaaaat aaacgaaggg acattagaag gtccatgcat gaaagaaaag
    18961 agagaggaag ttagcacaag ccctaaccaa gaattgtcaa aaaccgcacc ttgaagaagt
    19021 cctctgaaaa tgagttcctc ctggatgggg ccaaaaactg aggtagtcaa aatcaaagac
    19081 agggaaattc ctctgctgac ttccgccaag tgttggaccc ctgagccaga agaaacagcg
    19141 aagaaatgaa tataaaccag cgtctcaagt acacttagaa gaaagattgc aatgaaaagc
    19201 aaaagttgtt tcttgcttaa catcccaaaa gaaatcattt caaactttct agcataagca
    19261 acactcagcg aggttacaag aagacttaca agaatcaatg cagattcatt ttgaaaaaaa
    19321 tccccatggt taatcgtata aggaactata atgacaatta ttagtactaa aaatccaaaa
    19381 cacaaggcat gaaatttatc aaaaaactcc ataaaattat cctcctcaac aaacagactt
    19441 cctacacgtc attctttagt tctagccttt ccaaaacaaa ccattttata ctcttcgaaa
    19501 atcaaattca aaccacgtca acgtcacctt gccgtactca agtacagcct gcggctagtt
    19561 tcctagtttg ctctttgatt ttcattgagt attagtaacc aaaatccgac cacatagcca
    19621 gcccctatga atatagccat taaagctagc atggaattta ggaaattaaa aaccaccgca
    19681 gatacaaagg ttagcacaaa aacattaaaa gcaatggtgt cagaagccaa gactagaata
    19741 tagggtgtca accgatctaa agttttggaa tctaggaaaa ataagtgttt atacatgatg
    19801 acctcctcta tggctgaaaa gcaagccttt tgttttttta ccccaagacc ctatgtagaa
    19861 aagtgagcaa aaacgggaag gtcgctacaa tattattgat cacatgcacc gcataggatg
    19921 gataaatgct cttggtatag cgggtcaaac cagcaaagat gattccaact gttgcaaaga
    19981 cgaagatatc taacagacta ggcaggcttg aaaaatgagg gagagcaaat aaaatagaag
    20041 gaagaagcaa atcaagacca aatcgcgaat gcttaaagaa agcatgttgc agtaatcctc
    20101 tatagattaa ctcttccatc agtggaacca gaaagaacag ggctatataa atacctagct
    20161 ctgcaaagtt agtcccacta taaccaatca atacagccca accttccgca gttgactgaa
    20221 catgtttagc tgtctgaacg ttaaaagaga tctggaacac taccactaat actgtcaaaa
    20281 tcgaatacca aagccatttt tttcttggaa tgcggaagag ataaccatgg cctgtcttaa
    20341 caagaaccac aatcatgact ccaataaaaa gtaaactcaa gatattttga atccagacga
    20401 aattaccaat ctgggaagaa aattgccaat aattttggac gataagcgtc agctgagaaa
    20461 gaccaaatac gaaaaataag taagagaaga ctgcacttat tttgaataga agttgatact
    20521 ttttcataga aatcctccct catttcttgt atttcagcct atattccaca taaatgaaaa
    20581 cctgctccta tataaccacg gtcatgataa ccacgcaggc agtacccact tactggaaaa
    20641 ggacctgaat tttttaatat agaagggtaa gaagcgaatg gacttctctg attagcgtac
    20701 cctctataaa tatcagagac atccccatcc tctgtacgaa caagcatttc attatccata
    20761 acagaaaatt gtgacatcat ttttgtatcc atatagtata tcacttttca gttacggaac
    20821 aagtttaata taaaaattat caaaaaaaca taagcaataa agagaaaaat taatttatca
    20881 tagattagaa ataatatgac aaaacaattc aatgatgtta attcaatagt cttttgtttt
    20941 ttatcggaga tacttatgga tagataaata agataggttt gaaaagcgaa gagaataata
    21001 aagaatatag ccttcataaa atttagcttt catttttatg atgtagcggt ataggctaaa
    21061 tatccacaaa ccactgctcc tccaattcct cctattgcag cgccccatgg tcctagaagt
    21121 ctcccatatt tcactccacc cgctgcacaa cctaaagcag caactacagc tgctcctccg
    21181 gaattacctc cataaacctc actcagcatt gtttcattta tattacaata agtattcata
    21241 caagtctcct tttgttaaaa tccacccgtt gcccctgtta ctcctgccca aagagccaca
    21301 ccaaatttag ctcctatgta tccacatgct cccataaatg gcgctccaac accactcgca
    21361 gcacaaatag ctgtccctaa ccctgcccaa aacaaagcat cgtcaactcc aaatattcct
    21421 ccctctatcc tatcaagcat ttcattatcc ataacagaaa attgtgacat catttttgta
    21481 ttcatgacaa atactccttt tttatttttg tcttgttgta actttgataa gtttagtata
    21541 tcatcgtttt ttaaaatttt tcatccagat cttgaattgt catcgaaacg tcttgaatta
    21601 gcttttttat ttcaagtcac ctctatttca agccacctct aaatgtttaa aaaaaataat
    21661 ttctaatcac ttttttacca ttcaggaagt tttaatgact attcaagatt tcataaaata
    21721 tgaacttagt tttatgacat aatagaccta tccactatat gaaaggaatt gccaatgact
    21781 tcttataaac gtacatttgt tcctcaaata gatgcgagag actgtggtgt cgctgcctta
    21841 gcctcgattg ctaaattcta tggttcagat ttttctctag ctcacttgag agaacttgca
    21901 aagaccaata aagaagggac gactgctctt ggcattgtaa aagccgctga tgaaatgggc
    21961 tttgaaacaa gacctgttca agcagataaa acgctctttg acatgagtga tgtcccctat
    22021 ccatttatcg ttcacgttaa caaagaagga aaactccaac attactatgt tgtctatcaa
    22081 acaaagaaag actatctgat tattggtgat cctgaccctt ctgtaaaaat cactaaaatg
    22141 tcaaaagaac gctttttcta tgaatggact ggagtagcta tttttctagc taccaaaccc
    22201 agctatcaac cccataaaga taaaaagaat ggtctactaa gcaagcttcc ttcctctgat
    22261 tttcaaacaa aaatctctca ttgcttacat tgttctctca agcttattgg tcactattat
    22321 caatataggt ggttcttact atctccaagg aatcttggat gaatacattc caaatcagat
    22381 gaaatcaact ttaggaatca tctcagttgg tctggttatc acctatatcc tccaacaagt
    22441 catgagcttc tccagagatt atctcctaac cgttctgagc cagagattaa gcattgatgt
    22501 gattttatcc tatattcgcc atatttttga acttcccatg tctttctttg cgacacgtcg
    22561 tacaggagaa atcatttcac ggttcacaga tgctaactct attatagatg ccttggcttc
    22621 taccattctt tctctttttc tggatgtttc tattctgatt cttgtagggg gagtcttgct
    22681 ggcacaaaac cctaatctct tcctcctttc tcttctttcc attcctatat acatgttcat
    22741 catcttttct tttatgaaac cttttgaaaa aatgaaccat gatgtcatgc aaagtaattc
    22801 tatggttagc tctgccatta tcgaagatat caacgggatt gaaactataa agtcgctcac
    22861 gagtgaagaa aatcgctatc aaaatataga cagcgaattt gtagattatt tggaaaaatc
    22921 ctttaagctc agtaaatatt ctattttaca aacgagttta aagcagggaa caaaattagt
    22981 tctgaatatc cttatcctat ggtttggcgc tcaattagtc atgtcgagta aaatttctat
    23041 cggtcagctg attaccttta acacactttt ttcttacttt acaactccta tggaaaatat
    23101 tatcaacctc caaaccaaac tccaatctgc gaaggtcgct aataaccgtt tgaacgaagt
    23161 ctatctagtc gaatctgaat ttcaagttca agaaaaccct gttcattcac attttttgat
    23221 gggcgatatt gaatttgatg acctttctta taagtatggt tttggacgag ataccttaac
    23281 agatattaat ctcacgatta aacaaggaga taaggttagc ctagttggag ttagtggttc
    23341 tggtaaaaca actttagcca aaatgattgt caatttcttt gaaccctaca aagggcatat
    23401 ttccatcaat cattaggata ttaaaaacat tgataaaaaa gtcttgcgcc gtcatattaa
    23461 ttacctaccc caacaagcct atatctttaa tggctctatc ttggaaaact taaccttggg
    23521 cggtaatcat atgattagcc aagaagatat tctaagagct tgtgaattag ctgaaattcg
    23581 tcaagacatt gaaagaatgc ctatgggcta tcaaactcag ctctctgatg gagctggtct
    23641 atcaggagga caaaagcaac gaatagccct cgctcgtgct cttttaacta aatctcctgt
    23701 tttaatacta gacgaagcta ctagcggtct tgatgtcttg actgagaaaa aggttataga
    23761 taatcttatg tccctaactg ataaaaccat tctctttgta gcccatcgtc tcagtatagc
    23821 cgaacgaact aaccgtgtca ttgttcttga ccaggggaaa atcattgaag ttggtagtca
    23881 ccaagagtta atgcaagcgc aaggattcta ccatcatcta ttcaataaat aaggagaatg
    23941 tcatgaatcc taatcttttt agaagcgtcg agttttatca gagacgttac cataactatg
    24001 cgacagtgtt aattatacct ctttcattac tatttacttt catcttgatt ttctcccttg
    24061 ttgccacaaa agaaattact gttacttccc aaggggaaat cacccctaca agtgtcattg
    24121 catctattca gtcgaccagt gataatccta tccttgctaa tcatttagtg gcaaatcaag
    24181 tagttgaaaa aggggactta ctcatcaaat actctgaaac aatggaagaa agtcagaaaa
    24241 ctgccttagc aactcaatta caaagacttg agaagcaaaa agaaggactt ggaattttga
    24301 aacaaagctt agaaacaacg actgatcttt tttctggcga ggatgaattt ggctaccata
    24361 atacctttat gaattttact aaacaatccc atgatattga actgggtatc acaaagacta
    24421 acactgaagt ttcaaatcaa gctaatcttt ccaatagcag ttcatcagct attgaacaag
    24481 aaattacaaa agttcaacaa caaattggag aatatcaaga gttgagagat gctatcataa
    24541 ataacagagc acgcttacca actggcaatc cgcaccagtc aattttaaat cgttatctta
    24601 tagcctctca aggacaaaca caaggaactg cagaggagcc atttttatct caaattaatc
    24661 aaagtattgc aggtcttgaa tcatctatcg caagcctcaa aattcagcaa gctggtatcg
    24721 gaagtgtagc aacttatgat aatagtttag caaccaaaat tgaagtactc cgcactcagt
    24781 ttttacaaac agcctcacag caacaactaa ccgtggagaa tcaattaaca gaattaaaag
    24841 tacaactaga tcaagcaacg cagcgcttag gaaacaatac cttaaccgct ccaagtaaag
    24901 gtatcgttca tctgaacagc gaatttgaag gtaaaaatag aattccaact ggtacagaaa
    24961 ttgctcaaat attccctgtc atcacagata caagagaagt actaatcact tactacgtat
    25021 cttctgacta tctacctcta ctagataaag gacaaactgt aagattaaaa ctggagaaga
    25081 ttggaaatca cggcaccacc atcatcggcc aacttcagac aattgatcaa actcctacca
    25141 gaacagagca aggtaatctc tttaaattaa ccgctcttgc aaaactatct aatgaggata
    25201 gtaaactcat ccaatatggc ttacaaggtc gcgtcactag tgtaactgca aagaaaacat
    25261 attttgatta tttcaaagat aaaattttaa cccattctga ttaattttca gataacactc
    25321 tataactatt tattatctta tcaaaaagga gaatcataac atggataaga aacaaaacct
    25381 aacttcattt caagaactaa caactaccga actcaaccaa attacaggtg gaggactgtg
    25441 ggaagatatc ttatacagcc ttaatataat taagcataac aatacgaaag gacttcatca
    25501 tccaatacaa ctataaaaaa taagaccgag taacaagaac tctcggtctt atttttttca
    25561 tcattctgta ggtatcatag taagcacctg acgaaagact tgatcttgac aggtagtatt
    25621 taaactggca ttgggataac tttccacaat cttcataacg gtatagagac cgacacctct
    25681 ctcctcccct ttagaactaa ctccaaagga gaagatttca gaaatatcta tgccctcttc
    25741 tttgatggaa ttttcgatga tgaaggtctc ctgtgctcca ctttttaaaa aggcaattga
    25801 aacatgaggt tgaccggcct ctgcactcgc ttcaatagca ttatcacaaa ggatagacac
    25861 aatggttaga aaatcaagca gtctcatccc ctcaacctga atctcttcag gaacttcgac
    25921 attaaagaca atgtcctttt ctctagcttt tataaatttt ccagctagga gacttttgag
    25981 ggcacgatcc cgaacattca ccaatcggcc aaggtcatat ttattgtcct gcaatttttt
    26041 actagaatcc tttaagacca agtcatagac ctcttttatc tgctccatat cctcctcttc
    26101 aatacccaga cgtaaacttg tcaagaggtt ggtgtagtca tggcgaaaac tccttacttc
    26161 cttgtaaagt tcctctatat gccgactata gcgttccata tctctatagc gcaagacctg
    26221 ctcttggtcc agtctatcat ggagtttgtc cttcaaatag gtatccaatt tcttgataac
    26281 ccccataaaa aataggaggt aaaacactag gatgagatgg cgaacagtcg ttgattgaat
    26341 accttgctca tattcaaagt aagacagact ttgtatcacc aaatagtaag cccccattat
    26401 ccagttaatc ttagtcaggg acttttgaaa acctgtatct agaatctccc ttctcaaact
    26461 agtaaaatca tagtccaacc atttcaaaaa ggctagagaa atgaagaaat tgaaaattat
    26521 tatacataac ccagtaaatg agtagccatc atatacttgc tcttgtccca aaaatggaag
    26581 cacaaaatag gagactcctc tataaaagag attcaccaat atcattggaa agagaccata
    26641 aaagaaaagg agttttttag gaagccctct taacaataag aaagacaagc ctatgccgta
    26701 caagggttcc ataaaataag ataggtaaac atttcctatc atatagccaa tcattacaaa
    26761 aacaaaggcc aacagtatct tcaaaagaaa ggccttaaaa atcctctcaa aagtgagacc
    26821 aattccatct accttaaaga aaatgacaat ttctagccca ttagtaataa gtgtatacaa
    26881 tataatccaa aaaatataca taaatttcct agttcagtgt aagttattaa tagcctcaga
    26941 cacttccctg accttataac gcgcgatcag acagcttcca ccattgggaa agaaaaggag
    27001 tttttctttc ttatccaaat gcaccacatt tgcaggattg atgagaaaag agcgatggca
    27061 ctgcaagaga cggggttcct gcttaaaaac ctcctctaaa ctcgccgtaa attctagcct
    27121 gtccgtcttg gtatagagaa taacacgatg gggtcttggg gatgtttcga gatagtaaac
    27181 ctctttgaaa ggatattgga attgggcaaa ttttgattta aagtaaaagc aatcttccgc
    27241 cagactttta ctatcttgac tattggcata gaggagggct gtctcgatac gagattcaaa
    27301 ctcctctgcc gaaagggcct tatcaatgta gtccaaagct gacacttggt agcgaaagga
    27361 cagaggcata aactccgagt gagtcgtcac aaagacgatt agggcataag ggtcttgttc
    27421 ccgaatcttt ctagccactt ccagtccctt catctcttca tttcgaatct caatatccaa
    27481 aaagaatagc tgatgggccc ccttctcatg cacctctgcc agcagttggt ccggcttgcc
    27541 aaatacctca aaagagctag gaatgatatg atgtgctttc aaaagtttct caatcgtcgt
    27601 ttcaattcta gtctgttggg aaaaatcatc ttctaaaaca aatattctca tcttcttact
    27661 ctccctcttt caaccatttt tgacgtattt ctctatagcg acgtctggca tacctgacag
    27721 catattgacc ttcttctccg agaaaaagga ttctttcttg aaaatcaatc gattttaatt
    27781 tatcaagatt aaccaaacaa tttcgatgac atctcatcaa agtttcccca cattggttct
    27841 caagattact taaattttga agcatattaa aactagcttt ttctgtaaca atctgtacgg
    27901 tatgggcttt agttggatgt gtttggatat agtagatatc gtcgatgttt actttataga
    27961 ctgttttctg tgtctgaata atcatatgtt tcattggatt ctcctcctaa gaaaagaata
    28021 acagaaaaga tctagcccaa gcacacccaa tcctaaacag tctttgaaaa ctcctaaaag
    28081 gattattttc tacaacatca tgatgagctt acaactattt tatcataaaa ttcactcagc
    28141 gcaattcaag acatttcaat gacaattaaa gatttgaata aaaaaaagaa ttaaaagtga
    28201 taaactaaca gtatcaaaac acagttgcca gaagtaagac tggcacccag attaaaggag
    28261 gcattcccat gacagataca gaccccatca aaagagctca tactttgatt actgacttaa
    28321 acaaagccta ccaagcatgc aaacaggcaa gcgctgacga cgtccgcttt caggagcaat
    28381 taaactctat tcttggtttt ctagccaagg ctgaaacagt ggataatcga ttcttgattg
    28441 aactagaaaa attttaccag acttccagtc ttctcatggg actcagcgct cttgatccag
    28501 atgctccaac tcgtgccgct tggcgggcct atgaccgctt ccactttgac caagtcaaga
    28561 ccaagttaat actcaatgaa aatcaaagag caaactagga agctagccgc aagctgtact
    28621 tgagtacggt aagacgacgc tgacgtggtt tgaagagatt ttcgaagagt ataagtctct
    28681 acggaccaac cattatcctg tagtaacaaa aaagaagctg agacagactg aactcaactt
    28741 cttttttagt gtcgtatcag caatgttagt cctgcatctg acgttttacc tgataaggca
    28801 aatacaagac tagtaaaacc aaaccagctc ctagtaaggc tagaagggcc agtttttctt
    28861 ggaaggtaat caacccaaca actaattcca caagtaaaac aaaactggtc aatcctcgaa
    28921 ctacctcctg taagcctttt tccttttgcc ccttgtccag cggaaagagt tgggtcaaat
    28981 actggtagtc aaaggcatga tagagggcca gcaactggaa gagcaagagg tagttaaaga
    29041 gaactaccac tgctgtcgca atccaagctt gctcgataaa aacctgcgcc agtacggaaa
    29101 gtaagagaag acgaagactg agagcaaaga ggtcgccatt tcgcagataa gaacgcagat
    29161 agagattttg ccaaatcttc ccaggcacct tctgaacagc ctttaagata aagtccagat
    29221 aggcacgacg cttaacgctg tttgaaattc ccttgacctg cgtaaagagg gcaaagaaac
    29281 gaagcaagac ttgcttacgc ttgctttctt gggaaatgac atagtcccag tccagcccag
    29341 tttcagtgaa aaatttgctg gccttttgac gaaagtggaa atattttcct acccccaata
    29401 aaagcacata gagcagaaaa actggcaagc cataacccat tgctaaaaat aaaggcgcaa
    29461 ataacagcaa gaaaagggtc tgtacaaaga gccaaaagac tagggaaatg ccagtttgac
    29521 gcttgagatg gagcttgatt tcctcttctc caactaagag aaagagcttg tctggagcct
    29581 ccatataggt ggcaattcct ccccaaagta aaagtaaaac agacgtaatt cctacaaaca
    29641 aaaggatagg ccaatgattt tcaggaaaat gttgtaagag ttgactgtac tggtaggcta
    29701 gaaagcccaa caggacaagc aggaacaaga caaagtggtc attgagcaca tagcgcagat
    29761 aaccaagaca ctccttacga aaggcctgct ttctctttaa aaacaagtct ttcatagatc
    29821 ctcctctttg gtcagagcca agtaaatatc attcaaacta gcctcaggca tatcaaaggc
    29881 ttcacgtagt tgcaggagat tgcctttggc acgcacctct cccttgtgaa gaatgacaaa
    29941 ggcatcacac atcttctccg ccgaatccag cacgtgggta ctcatgagaa tagacttgcc
    30001 cttttgcttc tccacttcca aaagctgaat caaatcagaa atagccagcg gatcaagacc
    30061 aaggaaaggc tcatccacga tgaaaagact tggatccacc acaaaagcac agataatcat
    30121 gaccttctgc ttcatccctt ttgaaaaatg aacagggaac cagtctaatt tctgttccaa
    30181 acggaacatt tttaacaagg gctctactcg ttcgaaagcc actttttgct caataccgta
    30241 agccatagca accgtttcga tatgctctct gagggtcaat tcctcataca gactaggcgt
    30301 ctcaggaatg tagccaatct gcttgcggta gctagtcgca tctccttgca gagtcaggcc
    30361 attgatattg atggagccac tataaggtgc caacagaccg ataatctcat tgatcgtcgt
    30421 tgatttccca gcaccattga gaccaatcaa accgaccaac tgcccacttt caacagtaaa
    30481 ggacacatct ttcaaaacag gaacatgaac atagccacct gtcaggtttt taatttctaa
    30541 catattttct ccaaatctgg tataatgtag ctatattata tcaaaattca gtacagtaga
    30601 ggtagatttt atgtcagatt gcattttttg taaaatcatc gcaggggaaa ttcctgcttc
    30661 aaaagtatat gaagatgagc aggtccttgc ctttcttgat atctctcaag taacactagg
    30721 acacaccttg gtcgtgccaa aagaacacta tcgcaatctt ttggagatgg atgctacgag
    30781 cgccagccaa ctctttgccc aagtaccaaa agtagctcaa aaagtcatga aagtcactaa
    30841 ggctgctggt atgaatatca tttccaactg tgaagaagtc gctggtcaaa cagtttttca
    30901 tactcacgtt caccttgtgc ctcgctacag tgctgacgat gacctcaaga ttgattttat
    30961 cgcccacgaa ccagactttg acaaacttgc tcaagtcgct gaaaccatca aaaacgctta
    31021 aggagttgct atgaaattat ccaacctact gctatttgca ggagctgcag ccggaagtta
    31081 tctggttaca aaaaatcgcc aaaccatcac agatgaagtc ttgaatacca ctgaccgcgt
    31141 tcaagctatc aaggacgatg tggatattat ccaaaacagc ctgcaaatca ttaaccagca
    31201 aaaagaactt atcaaggaat accaagaaga cttgacttac aagtttaagg tcttggaaaa
    31261 ggatatccag actagactag ctgtgataaa agaaatgcag ggaactgaag ataagtaaaa
    31321 agagcccgac ggctcttttt taaaacgtaa acaagttata gtgaattgaa tttagaatag
    31381 cacatcatag tttctaaagc attgttagag attactttaa aatcctctta tcaatttgtt
    31441 catattctat ttcaatctac tatatatatc ccatcaacta tgcatcataa tttaggtaac
    31501 tcatactcaa taaaaatcaa aaagcaaact agaaagctag gcacagactg ctcaaaacac
    31561 cgttttaagg ttgtggatag aactgacgaa gtcagctcaa aacactgttt tgaggttgtg
    31621 gatagaactg acgaagtcag taaccatacc catgacaagc cgacgctgac gtggtttgaa
    31681 gaaatttttg aagagtatca ttcaccattt cacaactaaa tcgaagactt tctgccgtaa
    31741 tgaaaacacc tgaaacagct tggtttcagc tgtccggaaa ctttaagact taggttcaaa
    31801 gtttaggtat ggaacttcga aggaggtcgc taccgtccgt cattacttag gaaagtctta
    31861 aaaaatctat aaagtaaaaa gagcccgaca gctctttttg tttatactca atgaaaatca
    31921 aaaagcaaac taggaaacta gccacgggct gctcaaaaca ctgttttgag gttgtagata
    31981 cgactcacat atatacggca aggcaacgct gacgtggttt gaagagattt tcgaagagta
    32041 ttattctcca tcaaaggcat cttttatatg gtcaaagaag ccttttttct ttggatttac
    32101 tttcaagtca ccagcagtcg cgaattcttt caaggctact ttttggcggt cgttcaagcc
    32161 tgtcggtgtt acgacattaa cagtaacgta ttggtcacca actgcaccgc cacgaaggct
    32221 cggtgccccc ttactacgta ggcggaattt cttaccagtc tgagttccct ctggaataac
    32281 caattcaaca tcaccgtaaa cagttggaat atctactgta tcaccaagag ccgcttggac
    32341 aaagttgagg ttgagattgt agaagatagt cgttccttca cgttcaaact tgtcgctagc
    32401 ttctacagaa actactacat acaagtcacc ataaggtcca ccgttaaagc ctgcttcacc
    32461 ttgaccagcg aggcgaattt gttgacctgt ttccacacca gcagggattt tcacatgtac
    32521 gctatgagct tgtttctcat gacctgttcc atgacaggtt gtacatggat atttgatttc
    32581 ttttcctcga ccgtgacaga catcacaggt tacttggcga cgcatcatac caagaggagt
    32641 ctgcgtatcg acgttaatga caccagcgcc atgacagcgt ccacaagtga ctggacttgt
    32701 ccctggctta gcaccagagc cattacatgt acgacagcca gcttcacgat gatacttaac
    32761 ttccttctca gttccgaaga tagcttcttc aaaggtcaaa ttgacacgat actggagatc
    32821 atctccttgg cgaggagcgt ttggattgcg cgaagaaccg cctccgccga agaaacttga
    32881 gaaaatgtcc tcaaaaccac cgaagccacc tgccccattg aaaccaccga aaccaccagc
    32941 tccaccaaaa ccaccattgg cgcctgcagc accatactgg tcataggcag cacgtttttg
    33001 gtcgtcactc aaagtctcat aggcttcttg aacttccttg tacttgtcct cagcaccagg
    33061 ctccttgttg atatctgggt gatatttttt ggaaagctta cgataagcct ttttgatttc
    33121 gtctgccgaa gcgtttttgg atacccccag acgatcataa aattcagtat tgttcataca
    33181 agataccaag accgtaaaat tcgactgaaa aataggaaat ctgacgctgg agcgacgctc
    33241 ctagacagat ttctcttttt tccgagaatt taggtcgggt tcaattcctt tcttttatat
    33301 tgatgagata atactccagc cactcggccc tatccctttt taccgaaaaa cagaggctgg
    33361 gttacaacct ctgtggttag attattcatt tgaaataaaa atggttgtat tatctctagt
    33421 agtaatcttc aaagaccttt tagctaaatc aaactcaaat ttattatagt gtgggtcttg
    33481 tgttttatat aggtgtaact cctgacatat atgatccgaa aagtaaatca taacatcttt
    33541 aaacacagaa gtgtggtcat atttactctt accaacagct acttctgtaa attctttata
    33601 aatgacattt ccatttcttt ccacagtcac cagcatttct gttggattat aatccaaatt
    33661 aaataattat tcaaaaaact ttatcttttc atgataatct gcaatgtcag aaagattatt
    33721 tttattaaca ctcataacac tagcccctta tttttcagta aactctccgt ctacgacgtc
    33781 atcgcctgcg tttcctgttg cttgtgcgcc ttctgctcct tcttgagctt gttgcgctgc
    33841 tgcggcttgt tcgtagagtt tcacagcaag gccttgagct ttttcgttca acgcttcaag
    33901 tttcgctttc atgtcgtcca agttgttgtc ttcttgagct ttcttaaggt catcaagggc
    33961 agcttgggca gcgtcacgtt ctgcgtcgaa gcctttacct tcagtttcct tgattgtctt
    34021 ttcagtcgca aagattgctt ggtctacttc attacgaagg tctacttctt ctttacgttt
    34081 cttatcagct tcagcgtttg cttcggcatc tttcatcatg cggtcgattt cttcgtcagt
    34141 caaacctgag ttcgattgga tgacaatagt ttgttctttt tgagttccaa ggtctttggc
    34201 cttaacagac acgataccgt tcttgtcgat gtcaaatgtt acttcgattt gaggaattcc
    34261 acgaggtgca gctgggatat cagtcaattg gaagcgtcca agagtcttgt tatctgctgc
    34321 cattgggcgt tcaccttgaa gaacgtggat atcaacggct ggttggttgt ctgctgctgt
    34381 tgagaagact tgtgatttag atgttgggat tgtagtgttg cgatcgataa gttttgtaaa
    34441 tactccaccc attgtttcga taccaagtga caatggcgtt acatcaagaa ggacaacgtc
    34501 cttgacatca ccagtaatca caccaccttg gatagccgca cccatagcaa ctacttcatc
    34561 agggtttact gatttgtttg gttctttacc agtttcagct ttaacagctt caacaacggc
    34621 agggatacga gttgaaccac caacaaggat aacttcgtcg atttctgaca agctcaaacc
    34681 tgcatctgaa agggcttgac gaactggaac ttttgtacgt tcaacaaggt cacgagtcaa
    34741 atcatcaaat ttcgcacgag tcaaagtcat ttccaagtga agaggtccag cctcacctgc
    34801 agtgataaat ggcaagctga tttgtgttga agttacacca gaaaggtctt tcttcgcttt
    34861 ttcagccgca tctttcaaac gttgcattgc catcttgtca gtagacaagt cgataccgtt
    34921 ttctttcttg aattctgcta ccaagtggtc aatgattttt tggtcaaagt cgtcaccacc
    34981 aagtttgttg tcccctgcag ttgacaatac gtcgaagaca ccgtcaccca attcaaggat
    35041 agagacgtcg aatgtaccac caccaaggtc aaataccaag attttttctt ctttgtcagt
    35101 cttgtccaaa ccataagcaa gagctgctgc agttggttcg ttaacaatac gttctacttc
    35161 aagaccagca attttaccag catcttttgt tgcttgacgt tgagcgtcgt tgaagtaagc
    35221 cggaactgtg ataacagctt tggttacttt ctcaccaagg tagtcttcag cgtagccttt
    35281 caagtattga aggatcatag ctgagatttc ttgtggagtg tattcttttc catttgcaga
    35341 aactttttca gaagttccca tcttagattt gatagagata actgtatctg ggtttgtgac
    35401 tgcttgacgt tttgcagcat caccaacgat gatttctccg tttttgaatg agactacaga
    35461 tggagttgtg cggtttcctt ctgggtttgc gatgattttg ctttcagttc cttcaagaac
    35521 tgcaactgct gagtttgttg tacctaagtc aataccgata attttagaca tgtgtttttc
    35581 tccttgttag ttaattttct atttttcttt ttgatactct tcttaagtgg cgacgccgtc
    35641 agagcttgac ttcgtcaatc tctttgacta aactttgagc ctaaggtctc aaaatttgcg
    35701 caaatagcgc cacagcgaag agtatcgtct ttggttcgct tcgctcacta ttacaaagcc
    35761 aaacatattt tatctttctt catagtttat tgtcgtttcg gacaagtttt ctattatgta
    35821 aattgcgaca cgaggagtcg aaatcgattt tatttcgacg acgagttgct ttagctaccg
    35881 tcagaattgc cgaatcgaac acgccctaag ctctgagtaa aaaagataga ttttcttgtg
    35941 ttcatcgaac acttcgtcaa tctcctattt ttactgcgag ctttttacgg gctttgtatc
    36001 ttagttatac accactacca ttgctgggcg taggatgcgg tcatggagtt tgtagccttt
    36061 ttgaaagact tgggcgatgg tatctactgg gtgttcatcg tctgctggga gagtttggat
    36121 ggccatatgg tagttatggt caaattcgcc atctgctgcg atttcttcaa ttccttcttc
    36181 tttcaaagcg tgaatcaagc tttcttgcac catccccaag cccttcttca catcatctgt
    36241 caaaccttca actgcaagtg cacgctcaag gttgtcaaga gatggtaaga ttgcttttgc
    36301 caagtcctgg ctacgataac gttgcaagtt ttgacgttct tcgttggcac ggcgttggat
    36361 attttgcatt tctgcatgag cgcgaagata tttgttttcg aactcatctg cacgttcatt
    36421 tgccaagtcc aacttagact tttcaggagt tgtttcttca gctgtttcca caacttcctc
    36481 ttcttgaact tcttctactt cttcattttt tatatcttgg gccatgttcg cctcctttaa
    36541 tgatttcaat cttaatgtac ttcgtaatga ttactgctga ggtagcggta aaaatctgtc
    36601 aacttcatag tcaaaacacg gttgaccaca ttgacttgat tgattagctg ttggtaatcc
    36661 agattaactg gaccgataat ggctagaatt ccaactcctc gataaggaat gaggaactta
    36721 ctactaatca ccgctaggtc agctaaacag gactcttgac cgtctgcaac acgaacattt
    36781 tgcatctgat cctcacgcaa cccctcacga atctccaagg ccaccttttg cggttggtca
    36841 aagaactgat aggcttctag attggcaaaa ttcaagagat tgaccttgcc cgccatcaca
    36901 atgttttcgt tgaacatttc cttaaagatg tgttcaaaga gatcgatgac attatccgtt
    36961 gttgtaaagt aacgctggat aatctgcgga atctccgtcc gaatcttgta gtgaatatct
    37021 aaaacggtgt gaccgaggaa acgttcctga atgatgctct tcagtttcag caaatcctcc
    37081 tgcaagaagt tccttggaat cagaaactga ctagtaaccg ttcgcgactc gtctagggta
    37141 aataccgcca aggctgtatg ttgccccaaa acaacgatat caaaggctgt caaacgttgc
    37201 ctgctcggct caacatccag tgccactacc gtacagccac tcaggtctgt tagcaagtta
    37261 gcagcctctt gcagaatatc ctccaatttg aagaattcct gatcaaaggc tttgacaatc
    37321 tcatatacct cattttcagc cagccggtga aaatccagtg agtgtttcac atagtactga
    37381 aaaccagcaa cacttggcat ccgaccgctt gaagtatgag ccttctcaag caacccttgt
    37441 ttttctagtt ccgccatgtc attacgaatg gttgcactgc tagagttaat agactcttgc
    37501 aaggcttttg atccgacagg ttcgtgcgtt ttggtaaaga tgtcaataat cagatttaaa
    37561 atatcctgct gacgctctgt aaccatctca tcactcctct ctgtctgatc aattagcact
    37621 caatgcatcc aagtgctaac ttatgattct attatacacc cttaaaagag aatgtcaaga
    37681 caaaaactca aaaaattagc actcttttat caagagtgct aaaaatcaat ctgaagacct
    37741 agaaccttgc tattcatcta ctcggtattt cctttttagt ctgaaataac catgaattag
    37801 ataagaaatc agaaaagcat ataaaacaaa aataagaaag aaagacatag aaagatcctc
    37861 tctaaacaaa ctcgtacaaa caacaagacc acctaagaaa gtagttgtac aggaacgaag
    37921 tctagatcgc ataacttccc atttgagccc cttactcata tagacttgat cctctggaag
    37981 taaatcagaa gacgatttac gaagaatcga acaagaacct gctcctatca attcccaacc
    38041 tctatctcta aaatcttgca gttcatgctt atatttttta agaaatctag aatcatagat
    38101 acggtagatg acatcgtctg gttgacattg gtcaaaatag aacaaaccaa aacgactcgt
    38161 tctatacctc caacctttca aatgcatctc atgtaaatat tcttcttcct tgtccaaatc
    38221 aacaatggtg aaaatccgaa attctactct gctattcatt gtcttacccc aaaattagaa
    38281 aacatgcctg gcgttattta ttagataatt ctttccactt ttgactcaat ctccaaaaaa
    38341 tataagaaat ctgaatcgca aaaactatca ataaaaccca atctattatg aaaatcaaaa
    38401 acactttcca actgaaagaa ctacctccag tgacaaactt tgagaaaaac ggcagtagag
    38461 ctaaaaagag aagtaaaata ggaagcatcc gcattgttaa aatccgtttg gcataaaaaa
    38521 atctttattt aaacgaaaat attatagcaa aatttacgcc agtttttgaa cggctgatgt
    38581 agatatttta tactttcaaa atgtttaaat gtgattattt atttttgaaa aatagctcac
    38641 cagcccgact gaaagtgctt atagaatgat aataagtcgc ctgccgaaaa cagcggaaaa
    38701 tagcggtgtt atgcggagat aatctgacgc gatgcgaaag tatattgcat acttattttc
    38761 aacaatttag cagagtattt ttataagtgt gatataatag aagtataatt tgttctgata
    38821 gtttatttta tggagaagta gatttttaga atgcggaggg ttcaatatgg ttgagtttat
    38881 aaagtctaag aaagaaatga gtgaggagga tattaaagca aatttcatca ctcctgctat
    38941 tgtatccaaa ggatggaaaa atggtgagca tatcgcttac gaagaatact tcactgatgg
    39001 tcgaattgag gttagaggag ataaggctcg tcgtaaagaa ggaaaaaaat cagactattc
    39061 actgtattac caatttggaa ctcgaattgc aattgttgag gcaaaggata ataaacacag
    39121 cgttcgagca ggattacaac aagctattga atatggagag attttagatg ttccatttgt
    39181 ttattcttca aatggtgatg gctttattga acacgaccgt atcacgagag aagaacgtga
    39241 gctggagtta gacgaattcc ctactcgtga agaattattt tctcgtatga cgaaggaaaa
    39301 aggattgacg tacgaaatta cagaagctat ctcaactcca tactatacag acgccttctc
    39361 aatgaaaacg ccacgctatt atcagcaaat agctatcaac cgtactattg aaacagttgc
    39421 cagaggacaa aaacgagtaa tgtttgtgat ggcaacagga acggggaaaa cgttcatggc
    39481 ttttcaaatt attcatcgcc ttcgaaaagc tggtttggct aaacgagttt tattcttagc
    39541 ggatagaaac atcttagtag accaaacgat ggctgaagac tttaagccat tcgaaaaggt
    39601 aatgacgaaa attacaccaa aacttttgac tgctcctgaa aaattaaatt cttttgaaat
    39661 ttatctaggg ctttatcagc aactaactgg tgaagatgga actgaaacac attatcaaaa
    39721 atttgacaaa gacttctttg atttaatcgt aattgatgaa gcgcaccgtg gttcagctaa
    39781 ggaaaacagt aactggcgta agataattga ttatttcagt tctgcgacac agattgggat
    39841 gaccgctact cctaaagaaa ccaagaatgc ttccaatacg gaatactttg gtgagccaat
    39901 ctatacttat agtttaaaac agggaatcga ggatggtttt ttggctccat atcgtgttat
    39961 gagggttaat ttagatgtgg atgtggatgg ttatcgtcca gaaactggaa aagttgatac
    40021 taacggaca
//
LOCUS       DAVKMO010000013        39021 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVKMO010000013 DAVKMO010000000
VERSION     DAVKMO010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39021
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.013"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            567..2582
                     /locus_tag="VW361_000796"
     CDS             567..2582
                     /locus_tag="VW361_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9743886.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEVWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSILVLKGG"
     gene            2584..3216
                     /locus_tag="VW361_000797"
     CDS             2584..3216
                     /locus_tag="VW361_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743887.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSDSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVTLAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(4144..4557)
                     /gene="ndk"
                     /locus_tag="VW361_000798"
     CDS             complement(4144..4557)
                     /gene="ndk"
                     /locus_tag="VW361_000798"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU9743888.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(4668..8345)
                     /gene="rpoC"
                     /locus_tag="VW361_000799"
     CDS             complement(4668..8345)
                     /gene="rpoC"
                     /locus_tag="VW361_000799"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU9743889.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(8378..11989)
                     /locus_tag="VW361_000800"
     CDS             complement(8378..11989)
                     /locus_tag="VW361_000800"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9743890.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDREIGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12405..12475
                     /locus_tag="VW361_000801"
     tRNA            12405..12475
                     /locus_tag="VW361_000801"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12437..12439,aa:Cys,seq:gca)
     gene            complement(12673..14004)
                     /locus_tag="VW361_000802"
     CDS             complement(12673..14004)
                     /locus_tag="VW361_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU9743891.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(14295..15119)
                     /gene="endA"
                     /locus_tag="VW361_000803"
     CDS             complement(14295..15119)
                     /gene="endA"
                     /locus_tag="VW361_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU9743892.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     GPEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15158..15346)
                     /locus_tag="VW361_000804"
     CDS             complement(15158..15346)
                     /locus_tag="VW361_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9743893.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(15339..16622)
                     /gene="murA"
                     /locus_tag="VW361_000805"
     CDS             complement(15339..16622)
                     /gene="murA"
                     /locus_tag="VW361_000805"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9743894.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(16646..16876)
                     /locus_tag="VW361_000806"
     CDS             complement(16646..16876)
                     /locus_tag="VW361_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU9743895.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(16934..17971)
                     /locus_tag="VW361_000807"
     CDS             complement(16934..17971)
                     /locus_tag="VW361_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU9743896.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     LYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(17955..18443)
                     /gene="coaD"
                     /locus_tag="VW361_000808"
     CDS             complement(17955..18443)
                     /gene="coaD"
                     /locus_tag="VW361_000808"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU9743897.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDMIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKAVKHLGNVKVVSSHDKLVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(18433..18972)
                     /gene="rsmD"
                     /locus_tag="VW361_000809"
     CDS             complement(18433..18972)
                     /gene="rsmD"
                     /locus_tag="VW361_000809"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU9743898.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19037..20029)
                     /locus_tag="VW361_000810"
     CDS             complement(19037..20029)
                     /locus_tag="VW361_000810"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU9743899.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20141..20824)
                     /locus_tag="VW361_000811"
     CDS             complement(20141..20824)
                     /locus_tag="VW361_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU9743900.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYFLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLGFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(20880..21620)
                     /locus_tag="VW361_000812"
     CDS             complement(20880..21620)
                     /locus_tag="VW361_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU9743901.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            21654..21932
                     /locus_tag="VW361_000813"
     CDS             21654..21932
                     /locus_tag="VW361_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU9743902.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22010..22936
                     /gene="yidC"
                     /locus_tag="VW361_000814"
     CDS             22010..22936
                     /gene="yidC"
                     /locus_tag="VW361_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9743903.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23011..23805)
                     /gene="pflA"
                     /locus_tag="VW361_000815"
     CDS             complement(23011..23805)
                     /gene="pflA"
                     /locus_tag="VW361_000815"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU9743904.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(23931..25181)
                     /locus_tag="VW361_000816"
     CDS             complement(23931..25181)
                     /locus_tag="VW361_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU9743905.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLIRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25248..26075)
                     /gene="purR"
                     /locus_tag="VW361_000817"
     CDS             complement(25248..26075)
                     /gene="purR"
                     /locus_tag="VW361_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU9743906.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(26342..27283)
                     /locus_tag="VW361_000818"
     CDS             complement(26342..27283)
                     /locus_tag="VW361_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU9743907.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(27273..28529)
                     /locus_tag="VW361_000819"
     CDS             complement(27273..28529)
                     /locus_tag="VW361_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU9743908.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(28531..29193)
                     /locus_tag="VW361_000820"
     CDS             complement(28531..29193)
                     /locus_tag="VW361_000820"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU9743909.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(29156..29812)
                     /locus_tag="VW361_000821"
     CDS             complement(29156..29812)
                     /locus_tag="VW361_000821"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU9743910.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(29823..30701)
                     /gene="rsgA"
                     /locus_tag="VW361_000822"
     CDS             complement(29823..30701)
                     /gene="rsgA"
                     /locus_tag="VW361_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU9743911.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(30703..31575)
                     /gene="rsmA"
                     /locus_tag="VW361_000823"
     CDS             complement(30703..31575)
                     /gene="rsmA"
                     /locus_tag="VW361_000823"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU9743912.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFIHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(31706..32014)
                     /locus_tag="VW361_000824"
     CDS             complement(31706..32014)
                     /locus_tag="VW361_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743913.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(32007..32648)
                     /locus_tag="VW361_000825"
     CDS             complement(32007..32648)
                     /locus_tag="VW361_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743914.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVSLAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(32650..34680)
                     /locus_tag="VW361_000826"
     CDS             complement(32650..34680)
                     /locus_tag="VW361_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9743915.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQGLFTDYL
                     QNFSSESVEVTSQKYYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(34949..35848)
                     /locus_tag="VW361_000827"
     CDS             complement(34949..35848)
                     /locus_tag="VW361_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9743916.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIAHRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQGYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(35920..36480)
                     /gene="rnmV"
                     /locus_tag="VW361_000828"
     CDS             complement(35920..36480)
                     /gene="rnmV"
                     /locus_tag="VW361_000828"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU9743917.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTAIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLVGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(36480..37253)
                     /locus_tag="VW361_000829"
     CDS             complement(36480..37253)
                     /locus_tag="VW361_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU9743918.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALADEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKNLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(37558..38457)
                     /locus_tag="VW361_000830"
     CDS             complement(37558..38457)
                     /locus_tag="VW361_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU9743919.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKEKV
                     KVAILQANGSALDGATINVAGYGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATP
                     EYKLETTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESA
                     KNAIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETI
                     GVQAIVMVTVPKRPVAPNTAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAAL
                     ASLGLVVATSGFALLGRKTRRRK"
     gene            complement(38741..38875)
                     /gene="rpmH"
                     /locus_tag="VW361_000831"
     CDS             complement(38741..38875)
                     /gene="rpmH"
                     /locus_tag="VW361_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU9743920.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        11059 a         8879 c         7550 g        11533 t
ORIGIN      
        1 tttatgttta gtaacacaat tccttaccaa cagtttattc agaagaatag acaattggag
       61 attcgagtgc aatcacaaaa gaagtccaat ggtcttgatg ttgggaaggc tgattgattt
      121 cgtattactt taaaattcaa ctatttagag aaaggtattc tgatgagagc ttgtaacaat
      181 accagataga tataagaatg gagatgtttg ataaaatgct ttcatagcta accaactgtt
      241 gaaaattatg agttacaaaa tctaaagtat ttaagattgg tttataaaat taggtctctg
      301 cctgtagaaa ggaacgtgca gttagaaagg aggaaaaaat aggatactat aattcagact
      361 gagatttcta attaaaatat gtagttgcat ttcgctcatt ttcataatat ttcattcaga
      421 ggagtaataa tatgttaaaa tttacatttg atgcgggatg gtaaagaata attgaagaag
      481 attcttttat caatagttta gtaaacttgt tagtttatag agggtaggcg tatttctgcc
      541 ctctgtttta gaataaggaa tgcactatga aaaaattatt tatactcata tccaacctgc
      601 ttgctagttt gttctttgtt tgggtattta ccatttggac tgatacatat gtctcctatt
      661 attaccccaa cgttgttgta catgattctt cccctgaaac aacttttcag catgttgcta
      721 cacgcttgga aaaactagca gaagaaacag atagctttat tgcgattcaa caccaagatc
      781 ctaactcaga aggtactaca gttttttctt atacaacctt tggggacgga aagttgcctg
      841 atgggcttca ggaaaaaaaa ctagaagatg ctcaaagtag tagtgttgaa acaaactatt
      901 ttgtattcga tggacaccta gatattcact tgctaaggga ggagctaagt caacttggct
      961 tgactaatat gaacctgaca attccatcta aactatctac gttaatggct atctttagta
     1021 acggatttca gttaatcagt ctattgattt tcatcttaac ctttgtagca ctgactttaa
     1081 ttagtcaaat tagccaatta cggtcgtcgg gcattcgcct catttcagga gagaaacggt
     1141 ggtccatttt ccttagacca gttggtgagg atttgaaagg gatagctgtt ggtttcagtt
     1201 tagctggcgt gctcgccatt cttatgcaaa aaattctgtc gcttccaacg caatccctaa
     1261 tgaccatagg agcaggcttg ctcagttata atctcatctt gttgtcgatc tccctgtttt
     1321 tcgctcaact cttcgcagtt gggataaaaa agatacacct gatgcagatt ataaaagggc
     1381 aagtgcctgt cagaggaatc attagtttga ttttaatcgg tcaactatta gcgattatta
     1441 ttgtaacgct gggaataggg agtagcttaa agtattccca agcctggcaa cagcatcgga
     1501 ttggacaaga ggtttggagt caggaaaggc aactgattac cctatcaatc agccgtgaag
     1561 gaacgagtcc tggttttgat gaacaagctc aaaggaaact cagaacttgg tatcaattga
     1621 tggatctggc tgtttcagaa caaaaggctt tcttatctag acaccagtta attgaccgta
     1681 ctttgcaaaa tggcatggct tcctccaaaa acttgataac ctctacagaa tggcacgatt
     1741 acaacccgaa tggcaatgtc cttatcgtca caccgcaata cttggagcgt caaaacattc
     1801 ctgtagatac aactattgag caaaagatga atcaccttga tgtaggggag tttgtcttat
     1861 tgctgcctga acacctccgt tcagaggaag aacattataa atctgttttt gaagacgact
     1921 taaccagtcg catgtctagt caagatgaac gacagcaaat gactgctacg gtaggttatt
     1981 tagaatcagg tcaggatcgt tttgtgtata atacgacccc tatttcttac cagcagtttt
     2041 tgaaagatcc aatcatcatt gttataacac cccaatcaac tggtccacag tccattttgt
     2101 tttggataga cgcagtacag aactacgttc tctttaatca attgtctgat gcccaggagc
     2161 ttatccagag acaaggcatt gaaaattggg tctcagaaat gcaaacaggt taccacaact
     2221 acatcacatt attggataat atccagaggg aacgttgggt aatgctagca ggagctgtgc
     2281 ttgggattgc aacttcaatc ttgttgttta acactatgaa taggctctac tttgaagaat
     2341 ttagacgtgc catttttatc aaacgcattg caggtctcag gttcttagaa atccatcgca
     2401 cttatctctt tgctcaactg ggtgtgtttt tactgggatt tgttgcgagt gtatttcttc
     2461 aggtagagat aggagttgct ttcttagtct tgttactctt tactggtcta tctcttttac
     2521 agttacatgt ccaaatgcag aaagaaaaca agatgtccat tcttgttttg aagggaggtt
     2581 aatatgattg aacttaaaca ggtgagtaaa tcttttggag aacgagagtt attttcgaat
     2641 ctttcaatga catttgaggc tggaaaagtc tatgccttaa ttggttcaag tgatagcgga
     2701 aaaacaacct tgatgaacat gattgggaaa ttagaacctt atgatgggac gattttttac
     2761 cgaggtaaag acttggccaa ttataaatcg agtgattttt tccgtcacga attgggctac
     2821 ctcttccaga actttggctt aattgaaaac caaagtattg aagaaaacct taagctaggt
     2881 ctcattggtc aaaagttgag tcggtcggaa cagcggttga ggcagaagca ggctttagaa
     2941 caggtcggcc tggcttatct tgacctagat aagcgcatct ttgagttatc gggcggagaa
     3001 tcgcaacggg ttaccttggc aaaaattatc ttaaagaatc caccctttat tctggcagat
     3061 gagccaacag cttcaataga cccagcaacc tctcagttga ttatggagat tttgctatct
     3121 cttcgagatg ataataggct aatcattatc gcaacacata atccggcaat ttgggagatg
     3181 gctgatgaag tgttcacgat ggatcatctg aaataaaaat ccttgttttt aattgcacga
     3241 tgagttactg aaatattatc atgaatcaag aattggagtt aatttagaat tgtactttat
     3301 taatattgag gtaacttttt cttgataaag gaagaaataa tggagaggaa gttagaatga
     3361 aaaaattcga caattatatt attgagaagc cttgcgattc taattcagat aaactgcaaa
     3421 aaatcttaat aattgaaagt ttggtagatg atattttgca attttctctc agaatcaata
     3481 atagtgtagg agagattttc ctcctacaac cgttttaaaa gaaaactatc tttattccat
     3541 gttattttga ggaagatatt gtgaaagtca aagatgatga taaagttgag tggaatttgt
     3601 tagaatttca aaaatttaga gcatttttgg cttagtaatc tgtgttgaag gctcaaaacc
     3661 tatggtaaaa aagtagcttt gaaaacgtat tgcctccaaa gatttagtta aataatgatt
     3721 taacacaaaa agaaattatt gaagttctgg aaagatgttg tttcagtatt gagaaaaggt
     3781 gggaaaaact tgcgattttc acagagaaag gaagaaaaag tatagaaata tagtcaattg
     3841 aaacaagaac aggataaaag aaccttttgt gccatatttt tctcctttcg ctttacaatt
     3901 ggattgaaca cctttattgt atcgcgtttg gagttttttt ggtataacct tcgacgcgca
     3961 cccgcatagc gggtgttttt ttgtctcgca cctaacggag cgagacaaac taatagtcac
     4021 ttaatcaaaa aacgcaccat atcaaaaact aaaaagtttg atatcatgcg tcatgtctta
     4081 aactaattga ctatactttc tattcaaatg agcttttaac caattgattg agccaatcca
     4141 ctcttaaaac caaagagcaa tttctcgctt agctgactct tctgaatctg aaccatgtac
     4201 aacattttgg ataatctcat tttctccagc agcttttgca aaatcacctc gaatagtgcc
     4261 tggtaaagct tcttctggac gagttgcacc catcatggtc cgccaagttt cgattacttt
     4321 gggaccagaa atgacaccca caagaactgg acctgaagtc atgaattcac gaatcggtgg
     4381 gtaaaaactc tgaccaacca agtcctgata gtgctggtca atcaactctt ctgaaacctg
     4441 tgaacgaaac tccaattttt cgattgtaaa tccacgttgt tcgatgcgct ttaacacttc
     4501 acccactagc cctcttttta caccatctgg tttgatgata aagaatgttt gttccatacc
     4561 cgtctccttt gtcagcttct ttcttttatt ttaccacatt tcgtggaaaa atggagaaag
     4621 ttttcagaag agagaatgag agaaccctcg ggttctctca ttctctctta ttctactgtt
     4681 tcttccacag tttcaacggc agtatccaca actacttctg ttgtttcttc atttccttct
     4741 tcctctactg gaggattaag gtattcttct tcgttgacag catgtggttc aaggttacgg
     4801 taacgggcca taccagtacc agctgggatg atcttaccga tgataacatt ttctttaagt
     4861 ccaaggagat ggtctttctt accacggata gctgcgtcag taaggacacg agttgtttcc
     4921 tggaaggaag ccgctgacaa gaaactgttt gtttcaagtg aggctttggt aattcccata
     4981 aggactgggc gacctgtcgc tggaactcca cctgcgataa ggacatcttt gttggcatct
     5041 gtaaagtcat tgatatccat gagggtaccc atgagaagat ctgtatcacc tggatccatg
     5101 acacggactt tacggatcat ttgacgaacc attacctcga tgtgtttgtc accgatttct
     5161 accccttggc tacggtaaac tttttgtact tcaccgagaa ggtacgtttc aactgacaag
     5221 acatcacgaa ctgcaaggag acgttttggt tggatagaac cttctgtcag agcagcacca
     5281 cgcgctactt gtcccccaac ttcgacacgc atacgagctg taaatggaac gacatattca
     5341 ccttcgccag tttcaccctt aacaaagact ttcttggtac gagttgatgc atcttcttcg
     5401 atagcagtaa cttgtccttt aacctctgta ataaccgctt cccctttagg attgcgggct
     5461 tcaaagattt cttggacacg aggaagaccc tgagtgatat cggtatttga ggcaacccca
     5521 cctgtgtgga aggtacgcat tgtaagctgt gtaccaggtt ccccgataga ttgggcagcg
     5581 attgtaccaa ctgcttcacc aacttcaacc gcatcaccag tcgccaagtt gataccgtaa
     5641 cagtgacggc agacaccgtg acgagtgtta catgtaaata cagaacggat agtcacttct
     5701 tccacaccag cattgacaat ttcacgcgcc ttgtcttctg taatcaattc atttggacca
     5761 ataatcactg caccagtttc tggatgttta acagttttct tagtgtaacg accgttgaga
     5821 cgctcttcga gagactcgat catctctttt ccttctgcga tagaacggat caagagacca
     5881 cggtcagttc cacagtcgtc ctcacggatg ataacgtctt gggcaacgtc gaccaaacga
     5941 cgagtcaagt aacctgagtc ggctgtctta agggccgtat cggtcatacc tttacgagca
     6001 ccgtgagttg agaagaacat ttccaatacc gacaaacctt cgcggaagtt tgaaaggatt
     6061 ggcaattcca tgatacgtcc attcggagca gccatcagac cacgcatacc ggcaagctgt
     6121 gagaagtttg agatgttacc acgggctcca gagtccatca tcataacgat tgggttctta
     6181 ggatcttgat tagcaatcaa gcgtttctca agtttttcac gggcagcacg ccattcagct
     6241 gtaacagcat tgtaacgctc gtcatctgtg atcataccac gacggaattg tttggtgatt
     6301 tgttcgacac gtttgtgtga ttcttcaatg atttcagcct tgtcatcaac gactgggata
     6361 tcggcaatac ccactgtcaa tcctgcaaga gttgagtggt ggtaaccgag gttcttcatg
     6421 cggtcaagta gggcagaagt ttctgtcgta cggaaacgtt tgaagatttc agcgatgata
     6481 tttccgaggt ttttcttctt gaatggaggg ttgagctcaa gattgctgat agcttccttg
     6541 atatctccac caagtggcaa gaagtattta gctggaacac cttctgtcaa gttggcattg
     6601 tttggttctt gcaagtatgg tagcccctct ggcatgatat cgttgaagag aattttacca
     6661 actgttgtaa gcaagacctt atgtctttgc tcttctgtcc aaggcttgtt gaggctgtct
     6721 gttgcgatac caacacgtga gtggaggtga acataaccat tgcggtaagc cataaccgct
     6781 tcgtcacggt ctttgaagac cattccttca ccttcgcgac cagcttcttc catggtcaag
     6841 tagtagttac ccaaaaccat gtcctgagat ggagtaacta ccggtttccc atctttcggg
     6901 ttcaagatgt gctcagcagc tagcatgagg atacgagctt ctgcttgtgc ttcttctgaa
     6961 agtggtacgt ggatggccat ttggtccccg tcaaagtcag cattgtaggc ttcacagaca
     7021 agtgggtgca agcgaagagc cttaccatca atcaagactg gctcgaaggc ttggataccc
     7081 aaacggtgaa gggtcggtgc gcggttcaaa agcactgggt gttctttaat cacttcttca
     7141 aggatatccc agatacgctc atctccgcgt tccaccaagc gtttagctgc tttgacgttt
     7201 tgcacgatat cacgggcaac gatttcacgc atgacaaatg gtttaaagag ttcaatcgcc
     7261 atttcacgtg gcacaccaca ttggtacatc ttaagagttg gaccaacggc gataacggaa
     7321 cgtcctgaga agtcaacacg tttaccgagc aagttttgac ggaagcgtcc ttgtttacct
     7381 ttaagcatgt ggctcaatga tttcaatgga cggctacctg gtcctgtgat tggacgacca
     7441 cgacgaccat tgtcaatcaa agcgtcaact gcttcttgaa gcatacgctt ctcattttga
     7501 acgatgatac ctggtgcatt taactcaagc aaacgagcca aacggttgtt acggttgata
     7561 acacggcggt aaaggtcatt caagtcagat gaggcaaaac ggccaccatc caactgcaac
     7621 attggacgaa gatctggtgg gataaccgga aggatgttaa gaatcatcca ttcaggtttg
     7681 tttccagact tgtaaaaggc atccaaaaca tccaaacgac ggatggcttt gacacgtttt
     7741 tgtccagtag cagttttcaa ttcttctttg agttcagcaa tttctttttc aagatctact
     7801 tgcttcaaaa ggtcttggat ggcttccgca cccatcttag caacaaatga accataacca
     7861 tattcacgca agcgctctcg gtattcgcgc tctgtcatga tagacttgtg ctcaagtggt
     7921 gtatccttag gatcaatcac cacataagcc gcaaagtaga taacttcctc gagggcacga
     7981 gggctcatat caagggtcaa gcccatacgg cttggaatcc ccttgaagta ccagatgtga
     8041 gatacaggag ctttcaattc gatatgtccc atacgctcac gacgaacttt cgtacgcgtt
     8101 acttcaaccc cacagcggtc acaaacaatt cctctgtaac gaatgcgttt gtacttacca
     8161 caagcacatt cccagtcttt tgtaggacca aagatcactt catcaaagag tccttcacgt
     8221 tctggtttca aggtacggta attgattgtt tcaggttttt tgacttctcc ataagaccat
     8281 gaacggactt tacttggaga agctagggtg atttgcatac ttttaaaacg atttacatca
     8341 accactattt cttccctttc tattctaagt gaactgctta ttcttgttca gcagcttctt
     8401 ctgttgcttc cgcttttgtt gctttctcag cttcttcagc ttcaaaggct gctttagcct
     8461 cttgggctgc tttttcgcgg gctttttcaa ggtcatctac gtggatgaca tcttcgtcca
     8521 ttccttcatc caagtcgcga agttccactt cttggtcatc ttcgtctagg acacgcatgt
     8581 caagaccaag agattgcaat tctttgacaa gaactcggaa ggattctgga acacctggtt
     8641 ttggaattgg tttgcctttt gtaatagctt cataggcttt caaacgtccg ttgatatcgt
     8701 cagacttgta agtcaagatt tcttgaagga catttgacgc accgtaggct tcaagagccc
     8761 aaacctccat ctcaccgaaa cgttgtccac caaactgagc tttacctccg agtggttgtt
     8821 gggtaacagt tgaataaggt ccgactgaac gcgcgtgcaa tttatcgtca accatgtggt
     8881 ggagtttgat catgtacatg actccaacag aaacacggtt atcaaatggt tcacctgtac
     8941 gtccatcgta aaggattgtc ttggcatcgc tatccatacc tgcttcttta acagttgacc
     9001 aaagatcttc agaacttgct ccatcaaaga ctggtgtcgc aatgtgaata ccaagagtac
     9061 gagctgccat accaaggtga agctccataa cctgaccgat attcatacgt gatggcaccc
     9121 caagtgggtt caacatgatg tcgactggag ttccgtctgg aaggtaaggc atgtcttcta
     9181 caggaacgat acgagagaca acccctttgt ttccgtgacg tccggccatt ttatctccga
     9241 ccttaatctt acgtttttga gcgatgtaaa cacgaaccaa catgttaaca cctgattgca
     9301 actcatctcc atttacacgt gtaaagatct taacatcacg aacgacacca tcggcaccgt
     9361 gtggtacacg aagagaagta tcacgcactt cacgagactt gtctccaaag atagcgtgca
     9421 agagacgttc ttcagctgaa agatctttct cacccttagg tgttacttta cctacaagaa
     9481 tatcaccttc tttaacctca gcaccaatac ggataatccc catttcgtca aggtctttga
     9541 gggcatcttc accaacgttt ggaatttcgc gagtgatttc ttcaggccca agctttgtat
     9601 cgcgcgtttc tgattcgtat tcttcaaggt gaacagatgt gtagacatcg tccttcacca
     9661 agcgttcgct catgataacg gcatcctcga agttgtaacc ttcccaagtc atgtaggcaa
     9721 cgattgggtt ttgtccaagc gccatttctc cattttccat agaaggtccg tcagcgatga
     9781 aatcgccttt ttcaacgaca tcaccaactt ttacgagagt gcgttggttg taagcagtac
     9841 ctgagtttga acgacggaat ttttggatgt ggtaaacatc caatgaacca tcttcacgac
     9901 gaacttctac cttgtcagca tctgcgtaag taactttacc atcatactga gcaatcacag
     9961 ccgcaccaga atcgtgggct gcttggtatt ccataccagt accaacgtaa ggtgcctgag
    10021 gattaatcaa tggcacagcc tgacgttgca tattggctcc catgagggca cggttggagt
    10081 catcgttttc caagaaagga atacatgctg tcgcaacggc aactacctgt tttggtgaaa
    10141 cgtccatgta gtcaacaata ttagctggat actcttggtt gaccccttgg tgacgtccca
    10201 tgacaatctt ctcagcaaag gttccatctt cattcagacg agagttagcc tgagctacag
    10261 tatattcatc ttcttcatca gctgtcaacc aaacaatttc gttcgtgaca acacctattt
    10321 cacggtcaac cttacggtat ggtgtttgaa caaaaccata tttgttcaag tgtccgtaag
    10381 atgacaagtt attgatcaaa ccgatgttag gtccttcagg tgtctcgatt ggacacatac
    10441 gaccatagtg agtgtagtgc acgtcacgta cttcatatcc ggcacggtca cgagtcaaac
    10501 caccaggtcc taaggctgac aaacggcgtt tgtgagacaa ctcagaaagc gggttgtgtt
    10561 ggtccatgaa ctgtgacaac tgtgatgaac caaagaattc tttaaccgca gctgttacag
    10621 gacggatatt gataatttgt tgtggtgtca agacttcatt gtcctgaaca gacatacgtt
    10681 cacggacatt acgttccata cgagaaagtc ccaaacgtac ttggttggca agcaattcac
    10741 caaccgcacg gatacgacga tttccaaggt ggtcgatatc atctacacgg ccaagtcctt
    10801 cagccaagtt gaggaagtag ctcatctcag caaggatatc tgcaggagtc accgtacgaa
    10861 ccttgtcatc tgggttagca ttaccaatga tcgttacgac gcgatctgga tcagttggag
    10921 caacaacctt gaatttttga agaacaacag gctcagtcac aacggctgca tcgtttggga
    10981 tgtagacaat cttgttcaag tcgccatcca aatggctttc aatgctttca atcacgctac
    11041 gagtcataat cgtaccagct tctaccaaga tttctccagt ttcagggtct accaatggct
    11101 ctgcaatggt ttggttgagc aaacgtgttt taacattgag ttttttattg attttgtaac
    11161 gaccaactgc tgccaagtca tagcgacgtg ggtcaaagaa gcgagccaca agcaagctac
    11221 gtgagctttc agccgtctta ggctcacctg gacgaaggcg ttcgtaaatt tctttcaagg
    11281 cttcgtctgt acgagagtcc attggattct tgtggatatc tttttcaaca gtgttgcgaa
    11341 ccaattcgct gtcaccaaaa atatcaaaga tttcatcatc acctgagaaa ccaagagcac
    11401 gaaccaaggt tgtaaatgga atcttacgag tacggtcgat acgagtgtag gtgatatctt
    11461 ttgagtcgct ttcaagttcc aaccaagctc cacggttagg gataacagtt gaaccatagc
    11521 ccaccttacc atttttgtct actttgtcgt taaagtaaac acctggtgag cggaccaact
    11581 gagaaacgat aatacgttca ccaccattga tgatgaaagt acccatttct gtcatgattg
    11641 ggaaatcacc aaagaaaact tcttgggtct tgatttcgcc tgtttcttta ttgatcaagc
    11701 ggaaggttac aaaaattggt gctgagtagc tagcatcgtg gatacgagct tcttctagcg
    11761 tgtattttgg ttccttgatt tcatatccaa caaattccaa ctccattgtg tctgtgaagt
    11821 ttgaaattgg caatacatct tcaaacactt ccttaagacc gtggtctagg aaagctttga
    11881 atgagtcagt ttgaatttca atcaaatttg gtaagtcaag aacttctttg attcttgaaa
    11941 aactacgacg ggtacgatgt ttcccgtatt gaacgtcatg tcctgccaag atgattctcc
    12001 tttgtaaata agttccaagc cttgtcaatc aggcttttct aatcgccata tggttgtaaa
    12061 ccccttatca ccgtgtcctc ttgacgaatt ttcagaatct ttaagcctct gttacaaatg
    12121 ctcaaaatct tgaaaaaaag cacaaaaaga gcagctaaat ctgacttttt cagaagattt
    12181 aactgctgtg agccttgtct ggacaatatt tcagacaaaa cctacgacaa atgattaccc
    12241 atattatacc ctatttagct agatttttca aggggtttca gtaggttttt ggtaaatttt
    12301 ttcccataga aaacttggca tcacattcga atcacgctat ggtacaaaaa actgaaaaaa
    12361 ctattgactg aaaatcattt tcaaggtata ataataaacg ttaaggcggt atagccaagt
    12421 ggtaaggcac ggctctgcaa aagcttgatc gtcggttcaa atccgtctac cgccttctat
    12481 aacttgattt atcaggtttc aaatgaacag aaagcccaat ttgaagggct ttttttattt
    12541 tccctcgaat aaatacgtat aactttaaaa acttttggag cgagtttgtg gcagagttct
    12601 ttccatggca taattccctt ttgaaatcaa ttgaaaaaag cttcgtcacg cctggtgaca
    12661 aaagcctcta gtttattctg tttcttcttc tatttcgact tctgtgattt ggacttttac
    12721 cttggtaaca cgtccattct tcactttatc attggttaag ataaactgtt tgttttggct
    12781 gaccaattca tagctgagtt tctcagtcgt tggaatggtt cccactcctg tcaaataata
    12841 accagcgatg gtatcaacgt catcactttc cagttcaaca tcaaagtaat tattgaaatc
    12901 attgagggtc atagttcctt gaacaatgta ggtatcctcg ccaatctgat gaacatctat
    12961 tgctgctttg tccgtttcat catcaatttc accaacaatt tcctctaaga ggtcttccaa
    13021 agtcaccaaa ccagccatac caccgtattc atccagcaag attgccattt gtctttgggt
    13081 atttcgcagt tcttttagca agtcatccac aaaaatagtt tcaggtacaa aaagtggatc
    13141 ttgtaaaatt ctcttccaaa caatattgtc aaaaccgtcc acaaagcctg ccttaaggag
    13201 actcttggtg tgaatgattc caattacatt gtccttatcc ccatcataaa ccgggatacg
    13261 agaataattt tgttttaaaa tactttggat aatggcttga ctatcatcct gaatatccac
    13321 cataaaggca tccgttcgag gaaccataac ctctcgtgcc atcagttcat cgagcgaaaa
    13381 gacaccttgt agcatctcaa tctcatcagc atccaatgtt tcttcactat ttgtcagcat
    13441 ataggcaatt tcatcacggg tcatcttttc atccgcatca tcgaatgaca taggagtcaa
    13501 atggctcaag aaattggtcg aagcagctaa aagccaaaca aaaggactga ctagttttcc
    13561 gatcccaatg ataatcggcg ctgtacgaat tgccaaggca tcctttagat taagagcgat
    13621 tctcttagga tataattccc caaaaacgat ggaaatatag gtcaaaaatg ccaaggatag
    13681 aaaagttgcc acggcttgtg ctgtttcgcc attcccaagc caagaggcaa tcacacgtcc
    13741 tagagtatca gttaaactcg cccctgataa gattgtaatc agggtgattc ctacctgaat
    13801 ggttgataaa aagtggttag gattttctag taccttcagc aggcggatgt agcgtctgtc
    13861 tccttcttcc gccttttgtt caactcgggc acgattaaga gaaaccatgg ccatttctgt
    13921 ggctgagaaa aaggcattta ataccgtcaa gataaacaat aaaacaaatt gtagcaacaa
    13981 attctgacta cttgggtctt ccatagttct tctcctaaaa tagtatctta tcctttatta
    14041 tatcacaaaa tttaatccaa tacatattat ttttttctta gcgtaacttc catctctctc
    14101 ccaaaactgg aagttagtct aagacggatt tccactgatt tcacgcgttt ttctcatact
    14161 aaaagctagg ttgtgggaaa ctggaagtta gttttagaag ttactatttt ttcttagtac
    14221 ctgttctagc cctgcttaaa ctagtaaaaa gaactcctac atccataagt gacataggag
    14281 tttaggctta tcttttactg agttacagtt acttctccag ttcggtaatc cagttgaagt
    14341 cccttttgaa cattgggaac tagaacattg aattccaatt ctccatccga agacttggct
    14401 tcaatctgtg aagctgaggg aactaaatcc tcgtttgaag cgtagtaaag ggttacacgg
    14461 taacggacac gcttgttttg gtccaaggct ttacgcacct tgctttcata gtagttttga
    14521 ccagtcgaat actcggcttg tgcctgattt gcccaggctg tctgaacagc aatgttttta
    14581 ggattgcttg ttgaggcatc aaaaccatcc aaaccaccga ttaaggcata gcctaacaaa
    14641 tgacctctat cgactgcatg ggtataagag ccctttagat tcttgacctg atgccaacct
    14701 ggaggagtcc aagaagttga accattccca gtttctttac gattcttgta ctgacgagtg
    14761 gccttagaca agagggcatt agctacggtt ggaacagttt ccttgcccac tgtctttgtt
    14821 ttattgtcag cgtagggctt acttgaaacc ttggcatcta gatttgtttt attaccattg
    14881 acgataaaag cacctgagcc attccactcc agactcccct ttatttgact cttgactgcg
    14941 tctgttaaga cactctctgc caatgcttga ctaggagctt caggcccttg ttttttctga
    15001 ctaagattgg ttttgggact attaggtgcc gactgcatct gcttgatata atagctccct
    15061 gtagacaaaa gcaataacac tagcagtccg attagtgtct gtcttgtttt tttgttcata
    15121 tttctcctta tctttagaaa aaggctggtt ctccagccta atttcctgta aatttatgaa
    15181 tcaattcctg ccattttgct ggagacagga tagcccatgg atcttgaccc ttgcccaaga
    15241 ttccataacc taccattaga ccgattccta gagccagagt acctaaaatc agtactatga
    15301 tgactaaaag taaacgattg attacgtagc ttgatttctt attcatcttc atcgcttgcc
    15361 tcaatccgct gaatcttagc acctagctgc gccaacttct catggaaacc gtagtaacct
    15421 ctatccaagt gaaccaattt accgaccaca gtttctccct gtgctaccaa acctgtcaaa
    15481 atcaaggctg cactggcacg aaggtcagtt gaaagaactt ctgctccctg caaaggctgt
    15541 ccaccaacaa tacgagctgt atcacggata atctcagaat gcaagcccat gcggcgcatc
    15601 tcttctaggt gttggaaacg attttcgaaa actgtctcca ccatggttga ttcgcctttt
    15661 gcaactgtca tcaaggctgt aaattgagcc tgcatatctg ttggaaatcc tgggtggggc
    15721 aaggttttca catgaacagc ttttagattt tctagttgag aacgaacacg aattccttcg
    15781 tcttcttcaa ttacttcaac acccatttca agtaacttgg caatcaaggg acggttgtgc
    15841 tcccagacag cgtctcgaat caagacatca ccaccagtca tggcagcagc taccataaag
    15901 gttcctgctt cgatacggtc ttggactaca ttgtgagtcg taccatgaag tttctcaaca
    15961 ccagtaatgg ttatagtctc tgtaccagca cctttgacct tggctcccat ttcattaagg
    16021 agaatggcta agtcaacaat ctcaggctca cgcgcagcat tctcaatcac tgtcacccca
    16081 tcagccagag tcgctgccat catcaagttc tgcgttgcac caacacttgg aaagtccata
    16141 tagatatgag cgccatgcaa gcgttctgcc ttggcttcga tgtaaccagc tgtctgacta
    16201 atcttaaccc ccatagcttc cagacctttc aaatgaagat caataggacg gctaccaatc
    16261 gtacaaccac ctggcatgga taccttggca tgacccacac gggcaaggat tggccctaat
    16321 acaacgatgg aggcgcgcat cttgctgaca tacttgtaag gggcttcctc agtgatgtcg
    16381 ccagtagcat ccaccttgac aagatgagct tcctcatcaa agtcaacctt ggcattcaaa
    16441 ccaccaacta cctgattcat aataaagaca tccgacaaaa tcggaacatt ctgcaagacg
    16501 gtctttcctt cacttgctag aatagtcgct gccaacaagg gtaagactgc attttttgct
    16561 ccctcgatcg tcacgcttcc taccagacga ttatcgccac cttgaaccac aattttatcc
    16621 atactcgttt cctttactct tgatttcata ataatcctct aagcgcttct tgccacaaat
    16681 gatacaggct aataaagaaa gaactcagga tgtagcctat gacaatgcta aaaaaggcta
    16741 ctaataaacg aacttttctt gtattatcat ctgtcacttt taaaaccttc tcccatctaa
    16801 caagatcctt taaaaggtaa aaactcacat aaataaagaa catatgacta cttagagtga
    16861 ataataattg aaccatttga ctattatacc atcttctctg tttgtgcgct agtttggaaa
    16921 cttcactcaa aaattaggga ttgtttttca agtaatcaat cgcatcttgt agggttttaa
    16981 cgggcacgat tttcatatcc gtcttgattg ttttagccgc ttctagggct gtttggtagt
    17041 tgtttttcgc gtccggatgc gccttttgtt cttcttcgct aacagggtta tcaggagcaa
    17101 agaaaatagc agcacctgcc ctagccgaag ctacaacctt cttatcaata cctccaatgt
    17161 ctcccacatt accatcgcgg tcaatggtac ctgtaccggc aacaatacga ccattacgaa
    17221 gatctgggtg agctatttga gtatagatag ctagactaaa catgagacca gcacttggac
    17281 cgccaatacc agctgttgaa aagctaattg ggacattgct gattacctct gtacggtcaa
    17341 tcaagccgat tccaattcca tttttgccat tttccaaggt gatgattttt ccttctgcag
    17401 acttggtttg cccatcctct tcataggtga ccttgacgga atcccctaat ttttgagaac
    17461 tgacgtaatc aatcaagtct ttggaactat caaaggtctg atcattgact gctgtgactg
    17521 tatcagagat attgagaatc cctttaaagg ttgaattatc cgtcacattc aaaacataaa
    17581 ctccaaagta cttgagttcg atatccttac cagctgtttt tagtccttga tacttggcca
    17641 tattttgtga tgtttgcatg tataattgat tgattcgcat aaattcaaca tcggaagaac
    17701 cacctgtagt ctcctgagca ctacgaatat ctgtaaaagg tgtcaaccaa gcataaatca
    17761 tatgagctaa agtggcatgt tgaacaccaa ccgtaacgaa ttgataggca ccagcttcct
    17821 tatcttctgt gtcatttact ttaaggactt ggcgaatatc ttccgaacca cctggaacct
    17881 ctatataata aggcaagggc actacaaatg ccaagaaggt cacaatcaag gccgcaatga
    17941 cgtataaggg ccatctaatc ttttttttca tttcttattt cctccaaaat actctcggga
    18001 acatagcagg caatatcctg accaaacttc aaaagctctc taacgcctga tgaactgata
    18061 tagagatgtt caggtcgact atgtaaataa atagtctcta tatcagaaga cagctgatga
    18121 ttgtagtaat caaaactggc ttcatattgc aaatccgacg catttctcaa gcctcgcact
    18181 aggcaagtag cccccagtct ttttgcgaca tcgaccacca atttatcatg agaagacacg
    18241 actttaacat ttcccaaatg tttcacagcc ttttctaacc cccgtttacg attttcaaga
    18301 gggagaaatc cttgtttgtg gggattaaaa aaaataccca cataaagctt atcaaagagt
    18361 ctgctcgccc gttcaatcat atccagatgc ccatttgtca tcggatcaaa tgagcctgtg
    18421 aataagccaa tcttatctga catagactgt caccttacta attccataaa tcttttcctt
    18481 ccagataccc agacaggcaa tctcttctgg aagttcaacg gccttatccg tctcgcacac
    18541 aaccataaca tcttcagaaa aaagctctct ctcagccatt ttttcaatat ctgctacgat
    18601 ttgttccttg gcatagggag ggtctaagaa aacgaggtca aattccccag atacctgttc
    18661 caatgccctt tctgcatcca ttttgaggag ttgaaatttt ccaacttcct tggtcatctg
    18721 gatattttca gccacgatgg tctgagcctt acggtctcgc tccaccaaaa cagcactgga
    18781 catgccacgc gatactgctt cgatagataa accaccacta cctgcataaa ggtccaagac
    18841 tcgtcccact tcaaagtagg gaccaatcat gttaaaaatg gctcccctaa ccttatccga
    18901 agtaggtctt gttgtcttgc cttctagtgt cttgagggga cgtcccccat agattcctga
    18961 tacgattttc atactgttta ttataccaaa ttatagacaa aaagagaaag aaaaccgaac
    19021 cttgcggttc gattctctac aaaatatttt cgtaagtatc gcggacttct tgaggccaaa
    19081 cacttgtttg cacttctccg atgtgtctct tgcgaagtag gaacatggcc atacgagatt
    19141 gtccaattcc tccaccgatt gtcaatggga ataggccatt caacaaagac ttgtgccatt
    19201 ccaattctaa gcggtcttca tcacctgtaa tttccacctg acgtctaaga gtttcttcat
    19261 ctacacgaat tcccatagaa gacaactcaa aggctccacc taaagactca ttccagacaa
    19321 gaatatcacc atttagaccc ttgtagccat tctcagactc gcttgtccag tcatcatagt
    19381 ctggtgcacg tccatcgtgc ggtttaccat ctggcaactc gccaccgata ccaatcaaaa
    19441 agacggctcc aaattcttta caaatcgcat tttcacgttc tttaggtgtc aagtctgggt
    19501 agcgttctac caattcttct gtatggataa aggtgatttg ttttggcaag atagactcga
    19561 tgtcatagcg ggcttcaaca gctagctcag tcaggcgaat agccttataa atcttctcaa
    19621 ctgtttcttt tagataaacg atgttacgct taccatttgg aataaccttc tcccagtccc
    19681 actggtcaac ataaacagag tgggttgcat ccaaggaatc ctcatctgga cgaagggctt
    19741 tcatgtggac aaagagaccc tctccttcac caaagccaaa acgagccaag gtgtggcgtt
    19801 tccatttagc aagtgagtgc accacttcat aagtagcatc agggatttgg agaaccttga
    19861 ccgatactgg attttccaca ccagacaggt tgtcctgcat tccgtcaccg accttactca
    19921 agataggacc ttgaacttcg acaacttcta gcttatcttt caaatactgg gtaaaagtgt
    19981 ttttgacaaa ggaaatttct tcttgttgat ggataaaact tttcttcata gacaactcct
    20041 caaaaattta ataaacgtat tatacaccta tttccaagaa aagaaaagag aaaatttaaa
    20101 aaaaatcagt gtcactcaaa acactgattt catagacctt ttagtcattg cgaccaaaga
    20161 tacgtagaat acttaggaaa agattgataa aatcaagata gatgctgaga gccattgaca
    20221 ccacccagcc tgtcgctaca cgaccttgtg attgttcata ggcgaggcga atcttttggt
    20281 tatcccaagc aatcaaccct gaaaaaacca aaaccatggc tacgctaatc atataatcaa
    20341 agaagccact agccaagaaa atattgacta ccatagcaat cagtaaacca atgagagctg
    20401 ccatcattgc tcgaccaatc ccactcaagt ctttcttggt aaagatacca actgccgcca
    20461 tgacaaagaa gagaagggcg ctcgatacaa aggcagataa aactgtaccc ggagtataga
    20521 aagccaccac aaaaccaagg gtaaagccgt ttaaaacgga gtaaagtaaa aatactggaa
    20581 gagcagctgg actatttctt gaagccatgc tactggcaac gaaaaccaaa gccaactccg
    20641 caaaagtagc aatggtcaac cagagacgcc cctgcatcaa aaagtaaacc aactgagact
    20701 gaaagaccgt caacataagg cctgatacca aagcagatag tccgattccc agaccaacaa
    20761 aggcataaac cttagcgtaa aattgattga gacctgcacg gtcatgtata atagtgtgat
    20821 tcatccattt ctccttttct gtgaacatct ttccttgatt ataacaaaaa aagttaaaat
    20881 tagcttaaat ggaagattaa aataccggct gcaaccgcaa cattcaaact ctcggcctgc
    20941 cccttcatgc taatatggac caactggtct gcactttcag ccataagggg actaattcct
    21001 tgaccctcat ttcccataac tagtacaaaa ttttctatag aaggcagttc tctgtaatca
    21061 acagaatctt tagatagggt tgttgctagc actgggatag ctaccttttt agtttcgtca
    21121 agaagcgctt gactagtcat ccggtaaatg ggcagatgga aatgactacc ttgcatggaa
    21181 cgtagggttt tgagactgta gatgtctgcc gacttatctg aaacaatcac tcctgtaaaa
    21241 cctgctgcat ccgcagttcg aatgatagtt cctacattac caggatcttg cacatcttcc
    21301 aaaaacaaga acttgccctg actcaaatca gcttgtccta cttcttcttt ttgaaccacg
    21361 gcaacaattc cctgtggagt ctgagaatcc gccaaatcta gcaaaatatc ctctgaaatc
    21421 cagacagttt gcggaaaagc agctaactga tttcgataat tttctagggc aaagattttc
    21481 tcaatcgtca ctccagcttg gacagcttct tcaaacaagt gccagccttc aatcaaatag
    21541 gcagacttgc ggtatttttt ttggtgtaat ttcttagcat tttttaccac agaattggct
    21601 tttgaggtta taatagtcat agaaatatta taacacaatc aaaggggttt ggtatgcaaa
    21661 aggttagaat gattgcccaa ggtagggtgc agggagtcgg ctttcgttgg ggtgtttata
    21721 gcctggccct tgaaatcggt ggcatcacag gtcgggtatg gaataacgac gatggcacag
    21781 tggaaatctt agcccaagca gactcatctg ctatcatggc aaaatttatc caagaaatcc
    21841 gaaaaggacc gacacctttt tcaaaagtaa gctacttaga tgtcaaacta agcaactttc
    21901 ctccctactc tgactttaaa atcgcaaatt aggtctccag aactattgta tattttgtaa
    21961 aaaaacagta gaatagaaag gtataatttt taaagaagga ataaaaacag tgaaatctat
    22021 taaacgtttt gcattctcgg ctatgggagt ggctatgttg cttgtcttga ctggctgtgt
    22081 caatgtcgat aaaaccacag gtcagccaac aggatttatt tggaatacga tcggagcgcc
    22141 tatggctgaa gccatcaagt acttcgctac tgataaaggt ctaggctttg gtgtcgctat
    22201 cattatcgta accattatcg tacgcttgat tatcttacca cttggtatct accaatcatg
    22261 gaaggcaacg cttcactctg aaaagatgaa cgctctcaag catgtccttg agccacacca
    22321 aacacgtctc aaagaagcaa ctactcaaga agaaaaactc gaagcccaac aagccctctt
    22381 tgccgctcaa aaagagcacg gcatcagcat gtttggtggt gtaggatgtt tccctatcct
    22441 ccttcaaatg cctttcttct ctgctatcta ctttgctgcc caacatactg aaggggttgc
    22501 tcaagcaagc tacctaggca ttcctctagg ttctccaagt atgattttgg ttgcctgtgc
    22561 tggtgtcctt tactatcttc aatcgctcct ttcacttcac ggagtagaag atgaaatgca
    22621 aagagaacaa atcaagaaaa tgatttacat gagcccactc atgatcgtcg tcttctccct
    22681 cttctcacca gctagtgtca cactttactg ggttgtcggt ggtttcatga tgattctcca
    22741 acagtttatc gtcaactata tcgttcgtcc aaaacttcgc aaaaaagtcc gtgaagaact
    22801 agccaagaac ccaccaaaag caagtgcttt ctctaaacca agtggacgaa aagacgttac
    22861 ccctgaacaa ccaactgcta tcacaagcaa gaaaaaacac aaaaatcgca acgctggaaa
    22921 acaacgttcg agataagaag aaaaaggctt agctgatttg ctaagtcttt ttgcaaatca
    22981 aaagcccgat gtttccatca ggcttctttt ctatccatgt acacgtttca tataatcttg
    23041 ataactttcg gtatccatga gttttttagc gttcttgacg cgatctgctg ttggtggttt
    23101 gactccttcg agggaatatg gaattccaag ttcacgccac ttgaactcac ccatggtgtg
    23161 ataaggtaga atttcaaact tatcaacatt tttgagggtc ttgacgaact taccaagttc
    23221 aatcaagtca tcatctctgt ctgtcaatcc tggaactagc acgtggcgaa tccagacagg
    23281 ttttccaata tctgatagat actgggcaca agccaagata tttttattag tttggctagt
    23341 gacaatcttg tgctgttctt cgttgatttc cttgatatcc aaaagaacca agtcagtgac
    23401 agccatgagt ttgtcaaact tctcaaggta acgtggttta ttacggaaag gaagagcaca
    23461 ggtatccaag gtacagtgga ttccttgttc cttagccttg gtgaagagag caatcaggaa
    23521 atcaatctgc aagagagctt ctcctccact gactgtaatc ccacccttat ttccccagaa
    23581 accacggtag cgcaaggcct ctgtcaagac atcatctacc gtccgttcac gtgacttatt
    23641 ggactccata gcccaagtgt ctgggttgtg gcaatactgg caacgcatgt gacagccctg
    23701 caaaaagaca ataaagcgaa taccaggccc atctactgac ccaaagcttt ctgtcgaatg
    23761 caccattcct gtcacttgtc cataatcaat tgtttcttca gacatatcgt taccttcctt
    23821 gaaaacgttt tatagtttta ttatatcacg acttgaagga aaaacaagat ttttgcctat
    23881 tttttagaaa gcaatctgtt tttcaatttc attttcaatc tattatcaga ttattcttca
    23941 aaatcgaagc catataaggt tgcaaaatag tcctcagggc gctctgcacg gcggatttga
    24001 cgggctttac cttcttcggt atagaggatt tccgcagaac gtaatttggc attatactgg
    24061 tagcccattg aaaatccgtg ggcacctgta tcatgaatta ccagcaaatc accgatttct
    24121 gtatgaggca gttcgcgatt gactgcaaat ttatcattgt tttcacagag tgaaccaacc
    24181 acatctaccg cttcagctgg tccatctgga tgggtcacgt tgctaatatg atggtaagct
    24241 ccgtacatag ctggacgtat gaggttgact gctgaggcat ccacacctag ataggtacgg
    24301 taggtttcct tcttatgagt cactcttgtg actagagcac cgtgaggtgc cagcataaaa
    24361 cgacccaatt cggtgaaaat cttgacctga ccaagacctg ctgacgtaag aacttcttca
    24421 tacaccttac gaactccctc accaatcaag gcgatatcgt tcggctcctg gtctggacga
    24481 taattaacac caataccgcc agaaagattg ataaagtcta gcgaaatgcc caacttttcc
    24541 ttgatttcaa cagccagttc aaagagctga cgagccaact ctggataata gagatgggtc
    24601 acggtattgg acgctaggaa ggagtgaatc ccaaaagtct tggctccttt ttccttcaag
    24661 atagcaaagg cttcaaagag ctggtccttg gtcatgccaa acttagcctc cccaggattg
    24721 tccataatgt ctgtccccag ttcaaaaacg cctccaggat tataacgaca agagatgatt
    24781 tctggaatgc ctgctactct ctccagatgt tcaatatctt caaaggcatc caagttaatg
    24841 gtcgcaccca attcacgtgc ataggcgtat tccttgtctg gcgtgttgtt ggaagagaac
    24901 ataatctcag aacccagaaa gtccagttta tggctcatca aaagctctac ataactagag
    24961 cagtccacac cacaaccttc ttcttggaga attttcaaaa tagctggagt tggagtagcc
    25021 ttaactgcaa aatattcctt aaagcccttg ttccacgaaa aagcttggtt gacggctctt
    25081 gccttctcac gaatcccctt ctcatcatac aagtgaaagg gagtcgggaa ctcggcaaca
    25141 atcgcttcta actcttctct attgataaat ggtgttttca taagcttcct tctattctgt
    25201 ttgcaaagaa aggctgggac aatcgttcca acctttagtt ctatctctta tttatcttcg
    25261 tcaaagatat tgccaacctc aacatcgatg gcttggttct tgacatcaat attggttacc
    25321 ttcaagagtg acttgtagtc aaactgcttt tcacgttctt cttgggcatt gtccgcaaag
    25381 accgctacac ctgccagttc tgagtcgaac tcgcgcaaga gactaatcat accattgacc
    25441 gttccgccac ctttcaagaa gtcatccaca atcaagacac ggctgcctgc cttaagacta
    25501 cgttttgaaa ggaacatttt ctcgatacgg tcaccacttg aacctgaaac atagttgacg
    25561 ctaacagttg aaccttcggt aattttcagg tcacggcgca caatgacaaa agagacattg
    25621 aggacattgg caactgcatt tgcaagtggc acacccttag ttgctacggt cataaccgcg
    25681 tcaatttttt ggtccataaa gcttttggca ataatacgac caatattttt caagatggct
    25741 ggtgtgctaa gcaaatcaga cagatagata taaccacctg gcaagatacg gtcactttct
    25801 gacaacttgg tacgcaagtc ttcaaccatt tccttagcat cctgactcga aatagacggt
    25861 gtgaagatga cacctccgcc agccccagtc actgtctgga tatgaccgat ttcaatttcc
    25921 tcaaaggcgc gtttgataat gacgatatct tctgagatgg atgatttagc agactcatac
    25981 ttttcagcaa aagtattgag actagttagt ttataaggat tattaatcaa atagttggaa
    26041 atgacaacca tccgatcact tcttcttaat ttcatttcta tttcctattc catttttatt
    26101 caaaaaatca aaaagcaaac tagaaagctg gtcgctggtg gttcaaaaca ctgttttgag
    26161 attgtcaata gaactgacaa accctgtaat atacctgcat atatacatac gacaaggcga
    26221 tactacccta gtttgaagag attttcgaag agtattcatt tttgtctttt acttattata
    26281 ccatattcac ataaaaaaac gaacattctt atcctaaaaa atgctcattt ttcttaaatt
    26341 atcaatctaa atctggttta tagaaggaac gattatccat agcgaagatt ttattggtca
    26401 tctctccttt atccaccaaa gccagagctg ttgacatcat catcatgctt gcatccagat
    26461 tgtcaatcat atggataatc tctgcctcca taatacgtgg acggactgga cttccatatt
    26521 caagcaagcc gtggtgactg aggatgacat gacgaagcaa aacgacttct tccttggtat
    26581 catcgatgcc gagttccata actgtcttgg taatttcgct atcaatgaga gcgatatgtc
    26641 caagaagatt acctcgcact gtgtactctg tctggtctgg ccccgtcaac tcgataacct
    26701 tagctaagtc atgcagcata atccccgcat agagcaggct cttattgagc tgaggataaa
    26761 cttcgctaat agcgtctgcc aaacgtacca tggtcgccgt atgataagcc aaccccgttt
    26821 caaaggcatg gtggttggtc ttggcggctg gataggagta gaattcctta tcatacttgg
    26881 tgtagagatt tcggacaatc cgttgccaga caggattttc aattttgaaa atcatttgcg
    26941 acatgtagtc acgaatttcc ttgacatcaa ctggtgactt gaccttgaaa tcagctgggt
    27001 cattgggttc accagcttga ggcaggcgga gagtaatttg attgacttga ggggtattgt
    27061 tataaacttc tcggcgtcct ttcatgtgga caaccttacc tgcggtaaag gcctcaatgt
    27121 tatgaggttg ggcatcccag agcttcccat caatctcgcc actatcatct tggaaggtaa
    27181 aggctaggta gtttttccca gctcgagttt gcctcaggtc agctgatttg attaggtaaa
    27241 agccttcaaa taactcatct tttttcatgt gactaatctt catattcttc ctcattttct
    27301 tgaaaatgga gtagatcaag cgcaggctca ccttctgaca actcaatgtg acggagcgtc
    27361 cgctcgatag ctatggtacg acggtttaat aattcatcaa tattgccaga ggcatgttgg
    27421 agatgttttt gtgccttgac cagaatacca ccaaacttgc caaactcggt cttgacactg
    27481 gcaagagtct tgctgatatg gtcggcactc ttttggatat taagggtctt gaaaccaact
    27541 gatagggagt taagaagggc tgatagggta cttggtcctg caacaataat ctgttcttcc
    27601 cgtctcaaat catcaaagaa gaccggattg cggacgattt ctgagtagag accttctgtc
    27661 ggaacaaaca aaactccaaa attggtcgtc cgaggtggtg ctatgtactt gttcctaata
    27721 tccctagcaa agcgcttgac gcttgctagg agtgacttac gacagcgttc aatctcatcc
    27781 ttgtcacctg tctcataggc ttcttccaag cggtaataat ctgccagtgg aaacttagag
    27841 tcaattggca gataaacgta ttcttggtcg ccttgtccgg gtaacttgat ggcatactcc
    27901 actcgttcac tagagttttc aaccgttgcg tattctcgtt cgtactgggc aggtgtcatg
    27961 atgtcttcaa taatttgccc cagttgcaat tctcccagaa tccctcgcgt cttggttcca
    28021 gagagaacct tgttaagagc tccgacatca cgggcaactg tctgcatttc tccaaggcca
    28081 cgattgacag actccagttg tttagaaact gtctcaaagg aagcctgtaa gcgtgtctgc
    28141 aaggtctttt ctagtttttc ctcgaccgtc tggcgcattt gttccaaacg ttgctcattt
    28201 gattcctgca aggcttggag acgttggtct gtcttgtctc tagtttggag gagattatct
    28261 gtcatttctt gacggacttg ggtcagacct tggtgcaatt caatccgcac ttcttgcaaa
    28321 cggtcgctga caaccacttc caaatctttt tggtctaact ggctggcttg tctggcttgg
    28381 tcaaagcggt aatccaactg gtctgacaaa tgatctgcct gatcctccaa gctcttactt
    28441 aagtgtttct cctgcctatc ctgtctttgc caaatcagaa agagaccagc taggttggca
    28501 attaataata gaataagtaa actttccatc ctacctcctg tccttgctat gcagtacgac
    28561 cacataacca tctgggcaag tcaccgacac ttccctatct atatattcgt tagaagcgta
    28621 cactttttta aagaaaaaat tctcctctgt caactcatac ttagctccaa gaatagtcag
    28681 ctggctatcc cgaactggca taaaggctag atagtcgtag tctgaacgag gttctagctg
    28741 actggtccct tctgaacaat aggcaatcaa attttgccca tcctcaattt ctatttgacg
    28801 catatagggt gccaacttag gattgctagg tagaaagaca ttggccaaca tatggtcaat
    28861 acggccaccc aaggcaccga aaatagtgac ctcagcctga ggattttgtt caaagatggt
    28921 taagagagcc aattccaaat cagtatcatc tttttctggc cgggcttgga caaaatactg
    28981 ggcacgtttt tgaatcacct gtcgctcttc ttccgtcaca gaatcaaaat ctccgactgc
    29041 tagagcaaga ggtaagtctt cttccaagac ccagagcgag cctcgatcca ccccaacaaa
    29101 agcatcaaaa tctgtccgat aatgaccgcg gtttccgcct gcaaaaactg caaccctagt
    29161 ccagttgttt tctgagagtt tgtactcgct cattgacttc tcccttaaag acataggaac
    29221 ctgctacaaa aacagtcgca ccagcttctt tggcttgagc aatagtttgg tcatcaatcc
    29281 caccatccac ttcgatttca aagttcaaac ctttttcctc acgaagagca accaactcac
    29341 gaaccttatc catggtttct ggcagaaagg cttgcccacc aaaacctgga ttaaccgtca
    29401 tgactaaaac ttggtcaact agatgaagga cgtgcttgat ggcttcaact ggtgtgccag
    29461 gattgataac gactgaaggc ttaactccga gtgaacgaat tttttggagg gcgccatgaa
    29521 tatgaggtgt tgcttctaca tggatactga tgatgtctgc acctgcacgc gcaaaatctt
    29581 ccagatgatg ctcagggttt gacaccatca agtggcaatc gaaaaccatc ttactatgag
    29641 gacgaaggct ctcgaccaca cctgcaccaa aactgatttg cggtacaaaa tgactgtcca
    29701 tgatatcgat atgggcatat tctgccccag ttgcttctag acgtttgatt tcacgttcaa
    29761 agttggcata atctgctgcc agaattgacg gagcaatctt gtattgagac ataggtttct
    29821 ccttattttg gaattttttt gctgactttt ttataggttt ctctacgatt ttcaatttca
    29881 ctaaggaatt gcaggtaatt atcaaaacgg aaggttgcaa taacaccctc ttcaacagct
    29941 ggtttgacgg cacaagacgg ctcatgggta tgggtacaag tacggaactt acaatctcgg
    30001 ctaacagtag caatctctgg gaaagcctga ttgaggtctt cagcccttga tacttcatag
    30061 tccagagatg aaaagcctgg tgtatctgcg attttacccc cgttgagatt gtaaaaacta
    30121 acagctcgag tggtatggcg accgcgacct agactgtctg aaatttctcc cgtttcaaga
    30181 ttgaggtctg gtacgagttt attgagaaga gttgacttcc caacacctgt ctgccccata
    30241 aagaccgtaa ccttgcctgt taacaaagac aggagttcct ctttactggt cacaaagtca
    30301 tagccgatgt caccataggt ctgccggtaa aaatccagtt ctcccctatc ttccaacaaa
    30361 tccattttgg aaatatagac aatgggatgg atgcccttgt gctccaaaag aaccaagaaa
    30421 cgatccagca aattgctgtt aaaatcaggt tccttgacgg acatgattac tacagcttga
    30481 tcgatattga caataggcgg acgaactaga ctgtttttcc gttcgtgaat ttttaggata
    30541 tagccttctg aattttcctc ggcagagaaa tctacccagt ccccaacata aggggtatgg
    30601 ccttttttac ggaaattccc acgcgcgcgt gtttgataaa cctggccatc actctccaca
    30661 tagtagaaac ctgccaaggc tttaatgatt tgtccctgca tcttagagtc cttgcccttt
    30721 aagtgcgtct gctagaccgg caaattctgc caagctgaga gcttccccac gcacacttgg
    30781 tgacaagcct gcctggtcca aagccttggt cagcttgtcc ttgacctctt cagtcttacc
    30841 aaagtaacct gtcaagttat tccacaaggt cttacggcga tggataaaac tagccttgga
    30901 aaccttaaag aagaagttct catcttccac tgctacagct ggctctggac ggcgcaccat
    30961 tttcaagatg gctgaatcca catttggcgc tggcacaaag accgtacgag gcacgataaa
    31021 ggcaaccttg gctgtcatgt aatactgcac ggcgatagac aagctaccgt aagccttggt
    31081 gttaggctgg gctgaaatgc ggtccgctac ttctttctgc atcatgacca caaactcact
    31141 aaaaggaatg ccactctcaa tcaagtgcat gagaataggc gtcgtgatgt agtaaggcaa
    31201 attagccact accttgattg gcaggttagg atttttaaaa ttttggatat gttgcgccaa
    31261 atcaaccttg agaatatctt cgttaactac agtcacatta tcaaaatcac gcagggtatc
    31321 tgccaaaatt ggcaccaaac ggtggtcaat ctcaaaagcc atgacttggg ctgcacgctc
    31381 agccagaaac tccgtcaagg caccaatacc tggcccgatt tcgatgacat tgacctggtc
    31441 atcaatttca gccgtatcca caattttttg aaggatattg gtatccgtca ggaaattttg
    31501 cccgaaggac tttttaaagg taaaaccgtg acgctccagc actgccttgg tcacgctata
    31561 atctgcaatt ctcatctatt ctcttttcta ttatctgtta ctactattgt aacacattcc
    31621 ccttgtattt tgggaatgaa aatcatacca aaaaactatc tttcctcatg aagaaagata
    31681 gtcttggaaa tctttaaaag tggccttaac agttctctcg aaacatgcgt tcaaaaaaat
    31741 cagcttcttg ataacttcga ttttcgggta gggtcaaatc cacatcctcc tccacatcat
    31801 ccactgtcag ttcaaccgtc tgaggtaaat ttttcaaacg ataatgcttt tgcctttgcc
    31861 cttcaatact agcaaaatca agcaaatagc catgcactcg gatttgaacc aaaaggagat
    31921 gattggtcat attttccatg atgaggatat cttctaaacc acctctggca ctaggataat
    31981 cagataccct gcgaatacgg attttttcac acatgagcaa gtttcctcat atcaatgatt
    32041 tcatcagcct tattccagac taggggatta tgggtcgcaa tgatgataat tcgattttca
    32101 tctttcaaat ccaccaagag attcataacc tcctctgaat tttcaggatc aagagctgct
    32161 gttggttcat ctgccaaaat caagggtgga tttttcaaaa tagtcttagc aagggaaact
    32221 cgttgggcct ctcccccaga taaagtataa attttttgtt ctaaatccaa ataccctaga
    32281 ttaacttttt ctaaagcccc cacttgcctt tccaaacgtt ctacttttga gattttctga
    32341 ccaacaaaac ccaaatccaa attttctttg attgattggt tttctaagag gccaaaattt
    32401 tgaaagagat agcccatctg atctcgaaaa tactcacgag tgggaatggt ttttaaatct
    32461 ttcccctgat agagaaccct tcctccatct atcttttcta gctttcccaa gatattcagc
    32521 agcgtcgtct ttccgcttcc actctttccg attaaggcat aaaccttgcc cttctccagc
    32581 ttgagattca aaccagagaa aatcgcgcgg tcattaaatt tcttttccaa tccttgaata
    32641 tcaatcatct tattttcctt tcaatactgc catgctacca gcttcttctt ttttgtcctg
    32701 ccttactaaa atcaagaggg cgttaagcgt aaacaaagct acaactagag cgctaatcaa
    32761 accatctctt gtcaaaatac tagataggac taggccaagc aagagaactc ctccttgcgc
    32821 cagtaaatac ttgccatgaa gctcatagat tgtcatacca gcaagacgtt taatcataag
    32881 ctcccgtctg aactgctcaa aatagagaag attcatggaa tcaaataaca agatagccgt
    32941 agacagggtc aaaatcgtcc caataaggag agagtaaaac tccacccgtt tgtcatttag
    33001 taccttggca aaaaatagct ggctttttac caagtaagaa accttgtgat acagaccttg
    33061 ctcttttaga gctgtgatgc tgtctccata tcgatctagt ttcaaggcac tattagccgt
    33121 agttccccac aacatccctg caacaggtct tgttccagtc gcttgcggcg ttagaactac
    33181 aataatcgga tcttttaggt actggcgtgt tgtcttgtac ccatcattat agaggaaacg
    33241 ttcctgtcct gtttctgtaa aagctagcct tacctgtggg aggtagtatt tctgactcgt
    33301 cacttctaca ctttcagatg aaaagttttg caggtaatct gtaaacaatc cttggtagta
    33361 ggtagactgc tctcgcaagc tctcaggcaa gatcagccca aactctccct cagacaagtt
    33421 ttgcatcttg tccataaact ctgaagaaac ggtaatcttt tcttctatca gatagcgtgg
    33481 tgagacatag ataacattcc ctgacggtgt gtagtcactg agacgattgc catctaggtc
    33541 cacttctgct ccatctgaga aattgtcaac attgctcata atataaaaag agtctgtatt
    33601 ggctaaccgt tcttcagtaa atgtctgcca ctcacgatta tccttacgcg ttccttcttc
    33661 atcggcaaat gcactagacc aaccaaagga tagacggtaa cggtctgagg actggctcca
    33721 tttattgcta gctctctcca tttcctgcat ttcacggtag tggggtagga gagctgtcgc
    33781 actcgatccg accaccaata cagctaagag ttgccccacc atcatcaatg tcatcatacg
    33841 tttgagaggg agtttccctt tcaatagatc caccagacta ttttcctgta aaccaagtag
    33901 atagacgaca cttagtaagg tagaaatccc tgccagggtc aatccataaa gtagaagagc
    33961 aatgatgacc agttgcaccg ttgccataaa caaggcacct tgataccaga gaatccccaa
    34021 tcccaaaaga ctggatacca gcactgagca gataagctgt ctcacatctt ctaacactgg
    34081 tctgagagca actccaaaca agctctcacc agctattaag cgaatccctg cctgacgaag
    34141 ggatttgatc cgataaatca gggtcagact cataaaggtc agcagaaaaa tagctaaact
    34201 cagtagcacc ataggggtgg ccgtcaatag taagactatc gaaaatggat cttctccatt
    34261 cgaaacaaag ccttgatagc caagttcttt caaggtggtc tgtaagctca ctccatccaa
    34321 acttcctgac acaatcaagt aagaccctaa taaatcactc gtttctgcac tctccttgga
    34381 ggaaatggtc agaccttctg gaagctctcc ctcaccataa gtggcatagg taaagagtgt
    34441 ttctccagct tcatttggct caacgattcg acgggcgatg agactattat gctctaccgc
    34501 caagtgactc aaagcctctg tcacctcttc gcgactagct actggttgat ttatcatcat
    34561 tcctgtcaca tcaacagaag gatagttacc aaataaaatc tcttctcgat ggtcaacgga
    34621 agttatcacc atataaagcg ataccaatac cattgaaatc aaaataaata aacgtttcat
    34681 catttcctcc aaaaagttac ttggtcactt agtgagaagg tgaccacagt cactgcgatg
    34741 ttaagaagct tattaagttc tttctgctag caacatcttc aaatatatta tatccgtttt
    34801 ttcaagaact atcaaggaca tcaatgtcct taaaatctaa ctatttcata ttatttttag
    34861 cttatatcta aaaaaacagt tctaaagacg aactttagaa ctgttttgat acgaggacaa
    34921 ggacattttt gtcactgatt cactatgttt ataaatattt tttgacatcc tcttgccatt
    34981 cctctgtcaa tttctttact agaaatccat ctccaattag cttcgcaaat gttttagaag
    35041 actgataaaa tgattcagct aaactaaaat ctctttctac tcttaatgct tgcttccaca
    35101 aaaacataaa tacaagaggt ttcttttgat aaccttgagt tttatccata atttcttgta
    35161 aacacgatag ataatcatta aaacaatcag ttactcctac cttttcaaga caacacattc
    35221 ctgaaataag agtatctcta attataaagt aattctctat ttgagttacc ttcttctgtt
    35281 ccaaaagaaa gagcattagc ttttcgattt gatttataaa tttggcaaga tcttttctaa
    35341 tgagcatttg ataaaaaaac aaacgaatca acaacatatc atttgttgaa taaacttctt
    35401 tttctatgat ctgaggcata tgttcctcaa gtattaactc tgcatattca ggccttctag
    35461 ttctagaagt atccaaacac gcctgcaata cttcacatgc taattgttct tctttaggaa
    35521 gattatcaaa gtatgtttta taaatctctt ccaaacacgc ttctttctta tcatactcct
    35581 cttctttacc atagattggt tcacgtaaaa tctggtattt caattctaaa taagcaggag
    35641 gaagagctga aaaatccggc ataaggctat aaactggaac tcctagccgg tgagcaatat
    35701 agtctaactt gggcaaactc ggttgcgaag ctccactttc aattcgcgac agttgacgaa
    35761 ctgtcagttc ttgctcatct ccacaaaaat ctggacgact aattcctttt tctatccgaa
    35821 tctctttaat tttttgacca attaacatca gacgcctcct cttctacctg cttcgaaaaa
    35881 tactgtgaaa cttaaaaaat tgtaacggtc acatctttcc tactcataag atttcatagc
    35941 ttcttccact tctgccaaag taaccccaaa caactctagg cgtttgagga gttgcttgcc
    36001 gttagaatag ccgattcgga gagtctctcc gagatattcc ctacgcttac ggctgtctgc
    36061 ccctactaga aaaccaaggc gaatcaagtc gctacgacta atgtcaaact gactctcatg
    36121 ttcaaattgt tctgtcacct gagctagagc cgttttcagg tcttcatagc tggcatgctc
    36181 aattcccaga gaacgcccct tggtcttgga cttgggaaca gcttcatctc gcttgagaaa
    36241 ggcatgctga actgttggaa tggccgtcat aatcatgcgc cgaatccgct ccccattaaa
    36301 atctgggtct gtaaagacaa tgactccatg acgttggtgt agacgctgaa tccgctctat
    36361 gtcctggtca ttgatggcag aacctcgagt ctcataggtc tccacatcga aataacgctt
    36421 gagattgacc gtatcatcgc gaccttcaac cacgataact tgggaaattt tctctttcat
    36481 tacttgctgt ccaatccaaa aatgcgttct gcatttgcag tcgttgccgc cgctagctct
    36541 tctgtcgtca taccacgcaa gtcagcgata aagtccacca catagcgagt ataggctgtt
    36601 ttattttcac ggccacgctt gggtacaggt gctaagtaag gcgcatctgt ttccaccaac
    36661 atcttgtcca aaggtaactc tttagctgct tcttggaggt cagttgcctt cttgaaagtc
    36721 accactcctg agaaggaaat ggtcatacca agatccacaa acttctctgc ccactcaagc
    36781 gtccctgaaa atgaatgcat gataccacca cgaggaccaa cgccctcact cttgataatc
    36841 tcataggtat cttccagcgc atcacgggta tggacaacaa aaggcaaatc caagttctta
    36901 gatagctgaa tctgacggcg aaaaacctgc tcctgcacct ctttgggcgc tgtcatccaa
    36961 tggtagtcta agccaatttc acctaaagcc acaaccttgg aatgttttaa cttatccaac
    37021 aagtaagcct caacttcctc tgtataagta ccagcttctg taggatgcca accaatagtc
    37081 gcatagagct gctcatactc atctaccaac tccaaggcat gctcaatcgt cggtttatca
    37141 aaaccaacaa tattcatctg tgtcacaccc atctcatcag ccaaggcaat ttcttctgcc
    37201 tcacgacctg caaattcttc tacattcaag tgtgtatgtg tatcaaaaat catctcttct
    37261 aacctcgttt tctatcttct attataccaa aaaagaggag gggcacctaa tttttcggtt
    37321 tcccctcctc tcttcaatag ggagctattc tgctatcttt tctatccgat attgcccatc
    37381 tcctattcca cagttagaga cagaagagat tggctacatt gatagaatat tcctattcag
    37441 ctaaagtatg tgattatctt gggttctcac ttttctcacc catcactagg attgatgact
    37501 tctcaaaatc cctcttataa tctaacttta agtagagaat agaattttct agctgttcta
    37561 ttttctacgt ctagtctttc ttcctagcaa agcaaaacca cttgttgcca ccactagacc
    37621 aagactagca agtgctgcac ttgatgctga acccgtgtta ggtaattgtt tgccagcagg
    37681 tgactggtag gtaacatctt gcattgttcc tgcagttgct tgcggtgcac ttgttgtctt
    37741 aggagcagta ttaggagcca ctggtctctt aggaactgta accatgacaa tggcttgcac
    37801 tccaatcgtt tctgcttcct tcacatcttc catagttttc gcattttcaa tctctttgag
    37861 agctgcttgt ttttctgctt ccactcttgc taaaagttct gctttttctt tatcagaaag
    37921 cggtgcgcct ttgatttcat cctgcttgtc cttggctgct ttttcaatgg catttttagc
    37981 tgattctttt tcagtagcta attgcttaga agcttgtgat tgagctgagt tttgtgaacc
    38041 tgtgtgagct gatccacccg cctggctacc accgccttca ttcgcattag catctgagct
    38101 tccagtattg cctcccttat ctccacctgg tgtagtttct agcttatact ctggtgtagc
    38161 ttcttgagtt acagattcac ctttcgcaga ttgttgaact gtatcttttc ctagaatcgt
    38221 cactactgaa ccatctggga atgtgattgt tgctgtacca tatccagcta cattgattgt
    38281 cgctccgtct aatgctgaac catttgcttg taaaatagca accttaactt tttctttttc
    38341 ttcatctgtt aaatgagtta tatcttttac atctactctt tgagcaggtg ctttaacagt
    38401 tgatttttca gcagtcggtt tagtgctatc ttgtgctttt ggatcttgtg ctaccaattg
    38461 atttcctgga attgtaatag ctgaaccatc tttaaagacg attgttgctg taccatatcc
    38521 acctacttca actttatagt aaaataaaat aataacagga caaatcgatc aggacagtca
    38581 aatcgatttc taacaatgtt ttagaaacag aggtgtacta ttctagtttc aatctactgt
    38641 aacatcgctt ccgaatccat ttgcatctac tgaacttttt tacaaaaata aaaatcagta
    38701 gactcgagtt cctactgatt tttgatagaa ttcgtttgga ttatgcagcc aaaactttgc
    38761 gtcctttacg acgacgagct gccaatacgc gacgaccatt tttagttgac atacggttac
    38821 ggaatccgtg tttgcgcgca cgacgaagtt tacttggttg ataagtacgt ttcacgatga
    38881 atacctcctc atagattttg tattcgttta gccggctata aagtgatcag ttactaaaca
    38941 tactttacta ttctatctga ttctttcact tttgtcaata gctctaggca aatgtttcca
    39001 gctttttcga atgcaagccc t
//
LOCUS       DAVKMO010000014        37523 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVKMO010000014 DAVKMO010000000
VERSION     DAVKMO010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37523)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37523)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37523
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.014"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            42..157
                     /gene="rrf"
                     /locus_tag="VW361_000832"
     rRNA            42..157
                     /gene="rrf"
                     /locus_tag="VW361_000832"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            162..234
                     /locus_tag="VW361_000833"
     tRNA            162..234
                     /locus_tag="VW361_000833"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:195..197,aa:Val,seq:tac)
     gene            237..309
                     /locus_tag="VW361_000834"
     tRNA            237..309
                     /locus_tag="VW361_000834"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:270..272,aa:Asp,seq:gtc)
     gene            334..406
                     /locus_tag="VW361_000835"
     tRNA            334..406
                     /locus_tag="VW361_000835"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:367..369,aa:Lys,seq:ttt)
     gene            412..493
                     /locus_tag="VW361_000836"
     tRNA            412..493
                     /locus_tag="VW361_000836"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:446..448,aa:Leu,seq:tag)
     gene            512..584
                     /locus_tag="VW361_000837"
     tRNA            512..584
                     /locus_tag="VW361_000837"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:545..547,aa:Thr,seq:tgt)
     gene            607..678
                     /locus_tag="VW361_000838"
     tRNA            607..678
                     /locus_tag="VW361_000838"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:639..641,aa:Gly,seq:gcc)
     gene            686..771
                     /locus_tag="VW361_000839"
     tRNA            686..771
                     /locus_tag="VW361_000839"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:720..722,aa:Leu,seq:taa)
     gene            781..854
                     /locus_tag="VW361_000840"
     tRNA            781..854
                     /locus_tag="VW361_000840"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:815..817,aa:Arg,seq:acg)
     gene            870..943
                     /locus_tag="VW361_000841"
     tRNA            870..943
                     /locus_tag="VW361_000841"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:904..906,aa:Pro,seq:tgg)
     gene            949..1022
                     /locus_tag="VW361_000842"
     tRNA            949..1022
                     /locus_tag="VW361_000842"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:983..985,aa:Met,seq:cat)
     gene            1036..1109
                     /locus_tag="VW361_000843"
     tRNA            1036..1109
                     /locus_tag="VW361_000843"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1070..1072,aa:Ile,seq:cat)
     gene            1120..1209
                     /locus_tag="VW361_000844"
     tRNA            1120..1209
                     /locus_tag="VW361_000844"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1156..1158,aa:Ser,seq:tga)
     gene            1223..1296
                     /locus_tag="VW361_000845"
     tRNA            1223..1296
                     /locus_tag="VW361_000845"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1257..1259,aa:Met,seq:cat)
     gene            1300..1372
                     /locus_tag="VW361_000846"
     tRNA            1300..1372
                     /locus_tag="VW361_000846"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1333..1335,aa:Phe,seq:gaa)
     gene            1392..1462
                     /locus_tag="VW361_000847"
     tRNA            1392..1462
                     /locus_tag="VW361_000847"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1424..1426,aa:Gly,seq:tcc)
     gene            1498..1571
                     /locus_tag="VW361_000848"
     tRNA            1498..1571
                     /locus_tag="VW361_000848"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1532..1534,aa:Ile,seq:gat)
     gene            1578..1665
                     /locus_tag="VW361_000849"
     tRNA            1578..1665
                     /locus_tag="VW361_000849"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1612..1614,aa:Ser,seq:gct)
     gene            complement(1799..2236)
                     /locus_tag="VW361_000850"
     CDS             complement(1799..2236)
                     /locus_tag="VW361_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9743921.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEA
                     TNNLIKLIKCNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(2443..3378)
                     /locus_tag="VW361_000851"
     CDS             complement(2443..3378)
                     /locus_tag="VW361_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU9743922.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(3375..4235)
                     /locus_tag="VW361_000852"
     CDS             complement(3375..4235)
                     /locus_tag="VW361_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9743923.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVVFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            4343..6505
                     /locus_tag="VW361_000853"
     CDS             4343..6505
                     /locus_tag="VW361_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU9743924.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIYKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRRL"
     gene            6540..7799
                     /locus_tag="VW361_000854"
     CDS             6540..7799
                     /locus_tag="VW361_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9743925.1"
                     /translation="MEWYKKIGLLATTGLALVGLGVCSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKEQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            7813..8679
                     /locus_tag="VW361_000855"
     CDS             7813..8679
                     /locus_tag="VW361_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9743926.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDSKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAAFV
                     LGWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFLLIVVIS
                     IIQLRVSKKFEI"
     gene            8693..9526
                     /locus_tag="VW361_000856"
     CDS             8693..9526
                     /locus_tag="VW361_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9743927.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            9837..11279
                     /gene="gtfA"
                     /locus_tag="VW361_000857"
                     /pseudo
     CDS             9837..11279
                     /gene="gtfA"
                     /locus_tag="VW361_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
     gene            11417..12610
                     /locus_tag="VW361_000858"
     CDS             11417..12610
                     /locus_tag="VW361_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU9743928.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            13298..15277
                     /locus_tag="VW361_000859"
     CDS             13298..15277
                     /locus_tag="VW361_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9743929.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTNSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            15344..16840
                     /locus_tag="VW361_000860"
     CDS             15344..16840
                     /locus_tag="VW361_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9743930.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            16840..17766
                     /locus_tag="VW361_000861"
     CDS             16840..17766
                     /locus_tag="VW361_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9743931.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVVKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            17775..18842
                     /locus_tag="VW361_000862"
     CDS             17775..18842
                     /locus_tag="VW361_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743932.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            18853..19779
                     /locus_tag="VW361_000863"
     CDS             18853..19779
                     /locus_tag="VW361_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743933.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            complement(19854..21180)
                     /locus_tag="VW361_000864"
                     /pseudo
     CDS             complement(19854..21180)
                     /locus_tag="VW361_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21335..22045)
                     /gene="treR"
                     /locus_tag="VW361_000865"
     CDS             complement(21335..22045)
                     /gene="treR"
                     /locus_tag="VW361_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU9743934.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            22230..24197
                     /gene="treP"
                     /locus_tag="VW361_000866"
     CDS             22230..24197
                     /gene="treP"
                     /locus_tag="VW361_000866"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU9743935.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24375..26000
                     /gene="treC"
                     /locus_tag="VW361_000867"
     CDS             24375..26000
                     /gene="treC"
                     /locus_tag="VW361_000867"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU9743936.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            26256..26504
                     /locus_tag="VW361_000868"
     CDS             26256..26504
                     /locus_tag="VW361_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU9743937.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26711..27505
                     /gene="racE"
                     /locus_tag="VW361_000869"
     CDS             26711..27505
                     /gene="racE"
                     /locus_tag="VW361_000869"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU9743938.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27502..28473
                     /locus_tag="VW361_000870"
     CDS             27502..28473
                     /locus_tag="VW361_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU9743939.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28449..28970
                     /locus_tag="VW361_000871"
     CDS             28449..28970
                     /locus_tag="VW361_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU9743940.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28967..29428
                     /locus_tag="VW361_000872"
     CDS             28967..29428
                     /locus_tag="VW361_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9743941.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29419..30159
                     /gene="xerD"
                     /locus_tag="VW361_000873"
     CDS             29419..30159
                     /gene="xerD"
                     /locus_tag="VW361_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU9743942.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            30159..30887
                     /locus_tag="VW361_000874"
     CDS             30159..30887
                     /locus_tag="VW361_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU9743943.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLTFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30906..31475
                     /locus_tag="VW361_000875"
     CDS             30906..31475
                     /locus_tag="VW361_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU9743944.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31462..32184
                     /locus_tag="VW361_000876"
     CDS             31462..32184
                     /locus_tag="VW361_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9743945.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            32184..32426
                     /gene="yidD"
                     /locus_tag="VW361_000877"
     CDS             32184..32426
                     /gene="yidD"
                     /locus_tag="VW361_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU9743946.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(32651..33616)
                     /locus_tag="VW361_000878"
     CDS             complement(32651..33616)
                     /locus_tag="VW361_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9743947.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEITI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALTILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33712..34464)
                     /locus_tag="VW361_000879"
     CDS             complement(33712..34464)
                     /locus_tag="VW361_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9743948.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            complement(34461..35417)
                     /locus_tag="VW361_000880"
     CDS             complement(34461..35417)
                     /locus_tag="VW361_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU9743949.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(35407..36366)
                     /locus_tag="VW361_000881"
     CDS             complement(35407..36366)
                     /locus_tag="VW361_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9743950.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36789..37490)
                     /locus_tag="VW361_000882"
     CDS             complement(36789..37490)
                     /locus_tag="VW361_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEU9743951.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DDSCIRDYIYVLDLA"
BASE COUNT        10718 a         7079 c         8329 g        11397 t
ORIGIN      
        1 aattgaatag atattcaatt ttgagtaggt attactcaga gttaagtgac gatagcctag
       61 gagatacacc tgtacccatg ccgaacacag aagttaagcc ctagaacgcc ggaagtagtt
      121 gggggttgcc ccctgtgaga tagggaagtc gcttagctct agggagttta gctcagctgg
      181 gagagcatct gccttacaag cagagggtca gcggttcgat cccgttaact cccaaaggtc
      241 ccgtagtgta gcggttatca cgtcgccctg tcacggcgaa gatcgcgggt tcgattcccg
      301 tcgggaccgt ttaaggtaac gcaagttatt ttagactcgt tagctcagtt ggtagagcaa
      361 ttgactttta atcaatgggt cactggttcg agcccagtac gggtcatata tgcgggtttg
      421 gcggaattgg cagacgcacc agatttagga tctggcgctt aacggcgtgg gggttcaagt
      481 cccttaaccc gcattaagat ataacaaatg agccggctta gctcagttgg tagagcatct
      541 gatttgtaat cagagggtcg cgtgttcaag tcatgtagcc ggcattttta gatagaagaa
      601 aacagtgcga acgtagttca gtggtagaac accaccttgc caaggtgggg gtcgcgggtt
      661 cgaatcccgt cgttcgctta gagaggccgg ggtggcggaa ctggcagacg cacaggactt
      721 aaaatcctgc gattggtaac gatcgtaccg gttcgattcc ggtcctcggc ataatatgga
      781 gcacccttag ctcaactgga tagagtacct gactacgaat caggcggtta gaggttcgac
      841 tcctctaggg tgcatttttc tatttaactc gggaagtagc tcagcttggt agagtacttg
      901 gtttgggacc aaggtgtcgc aggttcgaat cctgtcttcc cgattcatgg cggtgtagct
      961 cagctggcta gagcgtccgg ttcatacccg ggaggtcggg ggttcgatcc ccttcgccgc
     1021 tataatgatc ttgtcggacc tttagctcag ctggttagag ctctcggctc ataaccgagt
     1081 ggtcgtaggt tcaagtccta caaggtccat ttgaatattg gaggattacc caagtccggc
     1141 tgaagggaac ggtcttgaaa accgtcaggc gtgtaaaaac gtgcgtgggt tcgaatccca
     1201 catcctcctt ttatattatt aacgcgggat ggagcagctc ggtagctcgt cgggctcata
     1261 acccgaaggt cgtaggttca aatcctgctc ccgcaataag gctcggtagc tcagttggta
     1321 gagcaatgga ttgaagctcc atgtgtcggc ggttcgattc cgtctcgcgc cattttattg
     1381 atagtattta tgcgggtgta gtttagtggt aaaactacag ccttccaagc tgttgtcgcg
     1441 agttcgattc tcgtcacccg ctttgaactt tgttcaaatt accaagtttt ttaacttggg
     1501 cgcgtagctc aggtggttag agcgcacgcc tgataagcgt gaggtcggtg gttcgagtcc
     1561 actcgtgccc attaattgga gaattactca agaggctgaa gaggacggtt tgctaaatcg
     1621 ttaggtcggg taactggcgc aagggttcga atcccttatt ctccgtttta atgagagttt
     1681 gtaactctct tttttatttt tagagacaat aaagcttcag atccgtaaaa cttaattgaa
     1741 ttactaatct gaagttattt ttatggctct ttgtcaactg tagtgggttg aagaaaagct
     1801 aagctcgaga aaggacaaat ttcgtccttt cttttttgat gttcaaagcg ataaaaatcc
     1861 gttttttaaa gttttcaaag tttcgaaaac caaaggcatt gcacttgata agtttgatga
     1921 gattattggt cgcttccagt ttggcgttag aatagtgtag ttgaagggcg ttgacaatct
     1981 tttctttatc tttgaggaag gttttaaaga cagtctgaaa aataggatga acctgcttaa
     2041 gattgtcctc aataagtccg aaaaatttct ctggttcctt tttcttcatt agacttccac
     2101 aatcagggca agatggagcc tcataatcca gcttagcgat aatttctttg tgggtatcca
     2161 tattgatgat atctagaatc ttgatgtttg ggtctttaat atcgagcagt tttgtgataa
     2221 aatgtaattg ttccatatga atctttctaa tgatggtttt gtcgcttttc attataggtc
     2281 atatgggact ttttttctac aacaaaatag gctccataat atctataagg gatttaccca
     2341 ctacaaatat tatagagcca ataaaacttc agatccgtaa aacttaattg aattactaat
     2401 ctgaagttat ttttatatcg tttatattat aattgtgtta ttttacttcc aactattgag
     2461 agaaatttcg ccactattta gccagatttc ttttccgtta tcacattgaa ctaaaagttt
     2521 tccattttct gagatgtctt tagcaagtcc cttgtagtct ttttgctcta gtgtgaaagt
     2581 gacttctttt cctagaatga atgactgttt tttgtatagg tataatagct cttctgctgg
     2641 tgtttcgaag aaagcacgcc agatttctat gatcaattca ttccttgtta taggagctgt
     2701 agctttaaat aagctggcag ctttttcttt taattcctga gggaagtctt taatagtgaa
     2761 attgatacct actccaataa tgatatctgt gactaagcca gtttctacag aggtcattgc
     2821 ttcagtaagg attcctccaa ttttatgatt gtttagatag atatcattga cccattttat
     2881 gtcgacatct attaaagtta ggttcttaat ggctttgtag acagctccag ctacaagtag
     2941 tgtgtaggat ggtaatttgt cataggggag atttggttta agatggagtg tcatataaat
     3001 accaccttgt ggtgagtaga aggaacgttg aaaacggcct cggcctgctg tttgatagga
     3061 agctagatag agggtatttg cttcatggcc taaatcaatt gcttcttttg catctagttg
     3121 tgttgatttt gtttcgggtt taaagctgac tttaattgga agattttctt ctagaatctc
     3181 tggaagaata aggtcaccat tcatcagttt gtatcctcta tttttgatac tatcaatttc
     3241 aatgccttct tgttctagtc gcttgatagc tttccaaatt gatgttcggc ttagggatag
     3301 tttttctgcg attttttctc cgctgatata gtcggtttct ttagatagga tttggtagac
     3361 agcttggtag gatttcataa tgttgccttt ctcactagtt ggtattgaga gtattctttt
     3421 cttgtatgac ttggagtctg attaaagtat tgtttataag ctttcgaaaa atggagtgga
     3481 tctgaaaaaa ctaccgagta tgcaattacc ttgatggact cttgggtatt ttcgagaagt
     3541 tgtctagctc ggtgcattcg aacgtagagt aggtattctt tgggtgataa ggtattaaat
     3601 tctttgaata cgcttgataa gtagcttctg tgaacggata gttcttttgc taaatcttga
     3661 attgtaagtg attgaggata gtggctatca attaatcgtt tgcattcaag atagagttgg
     3721 tgggttgatg aaatattctt ttttttctga ttgggagcaa tagttcccag atgaaacatc
     3781 agttcatgaa gttgtcccat gatatggagt tgagctaatt cacttgattt tgtaatctga
     3841 gcgaagcgga caatgtctga gatgagtttt gcagtagtct gggtatgaca agtttcagat
     3901 tggatgagat aggattgatc agaaatttga gaaagagcaa aataatcagg ggatttccct
     3961 ccagtgattc ctaaccagta gtaggcccaa ggttctttac tatctgcttg ataaaaggtt
     4021 agttcctctg gttttaatag aaagaaatct ccttctttta aatcaacaat tttacccttg
     4081 taatgaaatt ttccttgtcc tttagtaatg taatgtagga cgtatgtatc acgaatggct
     4141 ggaccaaaag agtaattagg tgtgcattcc tcatatccat aaaagcttag ggcaaggtcg
     4201 attgttccag tctggtattc tgaaaaaact aacatgtgct acctcctacc taacatttta
     4261 ccatattctt gagacatttt tctattttag aaagcgattt caggtgataa aatataatca
     4321 ataaagtgat gaggtgaagt aaatgggagt taggatagag aataatctat tttatgttga
     4381 gagtaaaaat ctaagtttga ttattgaaaa tcgaaatggc tacttacttt tgaaacattt
     4441 aggaaagact attaagaact ataaaggttc caatagtgtt tatgaacgag accatgcctt
     4501 ttcaggaaat ccaacagcta ctaatcgaac ctttagttta gatactcaac gtcaaatttt
     4561 tggacaacat ggcttaggag attttaggaa accaaccata caggttcagc ataatgtaac
     4621 tgaagtaaca gactttcgat ttgtagaagc aaagatttta aaaggtcaga atggtccaca
     4681 gggcttacct tctccacata gcatggacga tacagagact cttgtcttaa tgttagaaga
     4741 ttctaaggct caacttagtc tgactttgta ttatactact tttaataatg atgcgactat
     4801 tgctagctac agtaaattag ataataatag taatcaggaa gttgtcatct ataaagattt
     4861 ttcttttatg gctgattttc cagctgcaga ttacgaaata gtaactctgc agggtgctta
     4921 tgctcgtgaa aagactgtta gacgtcaaca ggtagaacaa ggaatctttt cgattagttc
     4981 aaaccgaggt gcttctggtc atgctcaaac accagctctt ctactatgcg aacaaggagt
     5041 cacagaggat gctgggaatg tgtttgctat tcaactaatg tatagtggca actttgaagc
     5101 ttttgttcaa aaaaatcaat tgaatgaagt tcgggtggct attggcatta atccagaaaa
     5161 cttttcttgg aagttagccc ctgaggaata ctttgaaaca ccggtagctt tagtgactca
     5221 ttcagatcag ggattaactg gtattagtca tgaaagtcag aattttgtac tgaagcacat
     5281 tatgctaagt gaattttcta aaaaagaacg tccaattcta atcaataact gggaagctac
     5341 ttactttgac tttcagagag aaaaactgtt agagttagca gatgaagcta agaaagttgg
     5401 cattgaactt tttgtattag atgatggttg gtttggcaat cgttttgatg ataatcgtgc
     5461 tttaggtgat tgggttgtta atgaggaaaa actgggtgga agtctagaaa gtctgatttc
     5521 agctatccat gaaagaggtt tgcagtttgg actttggtta gaacccgaaa tgatttctgt
     5581 agatagtgat ttgtatcgtc aacatcctga ctgggctatt caggttcctg gctatgagca
     5641 tacttattct cggaatcaat tagtacttaa tcttgccaat cctcaggtag tagaatactt
     5701 gaaaagtgtc ttagatcaac tcctatctta tcatgatatt gattacatta aatgggatat
     5761 gaaccgcaat atcactaagc tagggaatgg attaacttat ctagagacac agatgcaatc
     5821 tcatcagtac atgctggggc tttacgaact cgtttcttat ctgacagaga agcacagcca
     5881 tattctcttt gagtcctgct ctggtggtgg tggacgaaat gatcttggta tgatgcgcta
     5941 tttcccacaa gtctgggcta gtgataatac tgatgccatt gcacgtttac caattcaata
     6001 cggttcatcc tatctctatc caaccatttc tatgggggct catgtgtcag cagtaccgaa
     6061 tcatcagatg ggacgaatga caccattaga aacacgtggc cttgtagcaa tgatgggaaa
     6121 tttgggctat gaacttgatt tgacaaattt atcagatgaa gagaaagcta cgattgctaa
     6181 tcaggtgaac ttgtataaag aattacgacc agtagttcag ttaggacagc agtatagact
     6241 aattaatcct gatactgtat ccaatgaagc agctgtacaa tttaattacg gaaatcaaac
     6301 gattgtaacc tacgttcgcg ttttatctgt tgtagagacc atggaaacaa ctttaaaatt
     6361 aaaagatttg gatgaagagg gactatataa attacaggaa aatggcgaag tttactcagg
     6421 tgcagaacta atgtatgcgg gcctaactgt tatcttatcc caaggagatt ttttgagtag
     6481 acagtatatt tttagaagac tatgataagg gtgtataaat ttataaagga ggctttctaa
     6541 tggaatggta taaaaaaatc ggacttcttg caactacagg tttagctttg gttgggcttg
     6601 gcgtttgctc caactatggt aaatctgcgg atggcacagt gaccatcgag tatttcaacc
     6661 agaaaaaaga aatgaccaaa accttggaag aaatcactcg tgattttgag aaggaaaacc
     6721 ctaagatcaa ggtcaaagtc gtcaatgtac caaatgctgg tgaagtattg aagacacgcg
     6781 ttctcgcagg agatgtgcct gatgtggtca atatttaccc acagtccatc gaactgcaag
     6841 aatgggcaaa agcaggtgtc tttgaagatt tgagcaacaa agactacctg aaacgcgtga
     6901 aaaatggcta cgctgaaaaa tatgctgtaa acgaaaaagt ttacaacgtt ccttttacag
     6961 ctaatgctta tggaatttac tacaacaaag ataaattcga agaactgggc ttgaaggttc
     7021 ctgaaacctg ggatgaattt gaacagttag tcaaagatat cgttgctaaa gaacaaacac
     7081 catttggaat tgcaggtgca gatgcttgga cactcaatgg ttacaatcaa ttagcctttg
     7141 cgacagcaac aggtggagga aaagaagcaa atcaatacct tcgttattct caaccaaatg
     7201 ccattaaatt gtcggatccg attatgaaag atgatatcaa ggtcatggac atccttcgca
     7261 tcaatggctc taagcaaaag aactgggaag gtgctggcta taccgatgtt atcggagcct
     7321 tcgcacgtgg ggatgtcctc atgacaccaa atgggtcttg ggcgatcaca gcgattaatg
     7381 aacaaaaacc gaactttaag attgggacct tcatgattcc aggaaaagaa aaaggacaaa
     7441 gcttaaccgt tggtgcggga gacttggcat ggtctatctc agccaccacc aaacatccaa
     7501 aagaagccaa tgcctttgtg gaatatatga cccgtccaga agtcatgcaa aaatactacg
     7561 atgtggacgg atctccaaca gcgatcgaag gggtcaaaca agcaggagaa gattcaccgc
     7621 ttgctggtat gaccgaatat gcctttacgg atcgtcactt ggtctggttg caacaatact
     7681 ggaccagtga agcagacttc cataccttga ccatgaacta tgtcttgacc ggtgataaac
     7741 aaggcatggt caatgattta aatgccttct ttaacccgat gaaagcggat gtggattagg
     7801 agtagagaga ctatgaaaaa agtattacaa aaatattggg catgggcttt tgtggtcatc
     7861 cccctcttgt tacaagcaat tttcttctat gtgccgatgt ttcaaggagc cttttacagt
     7921 tttaccaact ggacaggatt gacttataac tacaaatttg tcggcttaaa caactttaag
     7981 ctcctcttca tggattcaaa attcatgaat gcgattggct ttaccgcaat cattacgatt
     8041 gccatggtgg ttggtgagat tgcactcggg atcttcattg cgcgtgtctt gaactctaaa
     8101 atcaaaggcc aaaccttctt ccgtgcttgg ttcttcttcc cagctgtttt atctggtttg
     8161 acagtggctt tgatcttcaa gcaagtcttc aactacggtc ttccagcgat tgggaatgcc
     8221 cttcatattg aatttctcca aaccagtctt ttagggacta agtggggagc aatctttgcg
     8281 gctgcctttg tccttggttg gcaaggggtg gctatgccca tcatcatctt cctagctggt
     8341 ttgcaatcta ttccaactga gattacagag gcagcaagga ttgatggtgc gactagcaag
     8401 caagttttct ggaacattga attgccttac ttgctaccaa gtgtctctat ggtctttatc
     8461 ctagccctaa aaggtgggct gactgccttt gaccaagtct ttgccatgac cggtggtggt
     8521 ccaaacaatg ccacaacctc acttgggctc ttggtttata actatgcctt taaaaacaac
     8581 caattcggtt atgccaatgc cattgccgta atcttgttcc tcttaattgt agtgatttcg
     8641 atcatccaat tgagagtatc taagaaattt gaaatttaag aggagaagca tgatgaaaca
     8701 agatgaaaga aaagccctga ttggcaaata cattctattg attctaggat cggttctgat
     8761 tttagtgccg ctccttgcta ccctctttag ttcctttaaa cccactaagg atattgtaga
     8821 taatttcttt ggctttccaa ccaacttcac atgggacaac tttagccgtc tcttagctga
     8881 tgggattgga ggctattatt ggaactctgt cgtcatcact gtcttgtctt tacttgcagt
     8941 aatgatcttt atccctatgg cagcctactc catcgctcgc aatatgagta aaagaaaagc
     9001 ctttaccatc atgtataccc tcttaatcct cggaatcttc gtacctttcc aagtcatcat
     9061 gattccgatt acggttatga tgagtaaact cggtttggct aatacctttg gtttgatctt
     9121 gctctacttg acctatgcga ttccacagac cctctttctc tatgttggct atatcaaaat
     9181 ctcgattcca gaaagtctgg atgaagcagc agagatcgat ggggctaatc aatttacaac
     9241 ctatttccgc atcatcttcc caatgatgaa accgatgcat gcgacaacca tgatcatcaa
     9301 tgccctttgg ttctggaatg acttcatgtt gccactcctt gtcttgaacc gggattccaa
     9361 aatgtggact ctgcctttgt tccaatacaa ctacgcaggc caatatttca acgactacgg
     9421 accaagcttt gcctcttacg tggtcggcat tatcagtatc accattgtct atctcttctt
     9481 ccaacgccat atcatttcag gaatgagcaa cggggcagtg aagtaatact caatgaaaat
     9541 caaagagcaa actaggaagc tagccgcagg ctgtacttga gtacggtaag gcgacgctga
     9601 cgtggtttga agagattttc gaagagtata agaagagctc atggaatcta tagtctttga
     9661 cacagaggaa gagttcagct tgttgataat tctatgtaga aaacaagaaa gtagtacttt
     9721 gtttatcaca gtctatatta gtacgagttt gatgataaat agagatttaa aatgaatttg
     9781 atttacgaag ccagatcata tgagacttgg cttcaattag aaaaaggaga gtaatgatgc
     9841 caattcaaaa taaaaccatg ttgattacct attctgatag ccttggaaat aatcttaaag
     9901 acttatatga taatttggaa gagcattttg gagatgctat tggaggagtt caccttttac
     9961 catttttccc atcaacaggt gatcgtggat ttgcgccagt tgactacgac gaagtggact
    10021 cagcttttgg tgattgggag gatgttaagc gtttaggtga gaaatattat cttatgtttg
    10081 attttatgat taatcatatt tctcgtcaat ccaagtatta taaggactat caagaaaaac
    10141 atgaagccag tgaatttaaa gatctctttt taaactggga taagttttag ccagaaaacc
    10201 gtccgacaca gtctgatgta gatttaattt acaagcgtaa ggatcgtgca ccaaagcaag
    10261 agattgtgtt tgaagatggt tcagtggaac atttgtggaa tacctttggt gaggagcaga
    10321 ttgatcttga tgtgaccaaa gaagtaacta tggaatttat ccgtaagacc attcagcact
    10381 tggcaagtaa tgggtgtgat ttgattcgtc tagatgcctt tgcttatgca gtgaagaaat
    10441 tggatactaa tgatttcttt gtggaaccag atatttggga tttattggac aaagttcgag
    10501 atatcgctgc tgagtatggg acagagcttt tacctgagat tcatgaacac tattcgattc
    10561 agtttaaaat agcagaccat gattactatg tttatgattt tgctcttcca atggtgacac
    10621 tttatactct ttacagttcc agaacagagc gtttggctaa gtggttaaag atgagcccga
    10681 tgaagcaatt tacgacgcta gatacccatg atgggattgg agtagtagat gtcaaggata
    10741 tcctgaccga tgaggagatt gactatgctt caaatgaact ctataaggtt ggagccaatg
    10801 tcaaacgtaa gtactctagt gccgagtata acaacttaga tatctaccaa atcaattcaa
    10861 cctactattc agcgcttgga gatgatgatg tcaagtattt tctcgctcgt ctaattcaag
    10921 cttttgcccc aggtattcct caggtttact atgtgggtct attagcaggc aagaatgact
    10981 tgaaattatt agaagaaact aaagaaggtc gaaatattaa tcgtcattac tatagcaacg
    11041 aggaaatagc aaaagaagtg caacgacctg ttgtgaaggc ccttctcaat ctattttctt
    11101 tccgtaaccg ttcagaagcc tttgatctag aagggactac tgagatagag acaccaacag
    11161 ctcacagcat tgtaatcaaa cgtcaaaata aagataagtc cgtaacagca gtagcagaaa
    11221 ttgatttgca aaatcagact tatcgggtaa ttgagaatgg agttgaagta acattttgaa
    11281 gccttgatat ggtggataaa atagggtttt tattttggaa aacgtttcct ttgttttcaa
    11341 attgctaaaa aagtggtaca atataggata gcttactatt atctgaatca gctgatttgg
    11401 agagaaagga ttcattttga aatcaatagg ctttattgaa aagctgaagg ggttgtctag
    11461 taaagagctg attttattgg gaattatcct aagtatcttt ttaccctttt atctttttgt
    11521 agttgtactc tgtttatata ttatcagttt gatttttaca ggagacatga aaagtattct
    11581 tcagaaaatg ggggagcatc cgatgctgct tctttttctt agctatagta ctgttatatc
    11641 cattcttgca caaaattgga tgggtcttgt ggcttcagta ggaatgtttc tatttactat
    11701 tttctttttg cactatcagt cgattttatc ccataaattc tttcgattga ttttgcagtt
    11761 cgtcttgttt ggtagtgtct tgtcagctgc ttttgccagt ttagaacatt tccaaattgt
    11821 gaagaaattt aactatgctt ttctttcacc caatatgcag gtgtggcatc agaaccgggc
    11881 agaagtgacc ttctttaatc ctaattatta tggaattatt tgttgtttct gtattatgat
    11941 tgctttctat ctgtttacaa cgaccaagtt gaattggttg aaagtattct gtgtgattgc
    12001 aggctttgtt aatctctttg gtttgaactt tactcaaaat cgaactgcct ttcctgctat
    12061 tatcgctgga gcaattatct atctctttac gactattaaa aactggaagg ccttttggct
    12121 tagtattggg gtcttcgcga ttggtttgag tttcctcttt tctagtgatt tgggagttcg
    12181 aatgggtact ttagactctt ctatggaaga acgcatttct atctgggatg ctgggatggc
    12241 cttgtttaag caaaatcctt tttggggtga agggccattg acctatatgc actcttatcc
    12301 tcggatacat gctccttatc atgaacatgc ccacagtctt tatattgata cgattctgag
    12361 ttacggaatt gtgggtacca ttttattagt tttgtcttct gttgctcctg ttcgcttgat
    12421 gatggatatg agtcaggagt cggggaaacg tccgattatc ggcctttatc tatctttcct
    12481 tacagtggtt gctgtgcacg gaatttttga cttggctctc ttctggattc agtcaggctt
    12541 tattttcttg ctagttatgt gcagtattcc attggagcat cgaatgttgg tatcggacat
    12601 gacggattaa gttttataag tttgaaatct tctaccttgg gtaggagatt tttttatacg
    12661 atgggcatgt cgtgcatctg aggtgtaagt cctctgtagg gatccactac cggtgaatac
    12721 aatagcgctc cccaagcctg actatcgtga ggtagcggat taaaatggtc tggggataga
    12781 tcgttttaag tctgacgcag gaaataagaa ttgtcagaga aagcaatagt gaaatcgtag
    12841 gctatgaata gaaacgtgat agcgaggagc atatagtgga taaggtagcg agaaatttta
    12901 aagtataaaa gatagtctta atctatatat gtaaatcaca aaagtaattg aattcggaat
    12961 aaggttggtg tgaaaagaca tagtaaactg aatcttgaat actagaatga tacttctaca
    13021 atattgttat aatttaattt gaattccaaa atcacattgt tccgtccgta tttcatttta
    13081 ctgtatgtct tcctaaactc caaagtttct gcgtcaaatt tcctattttc actgtagtct
    13141 ttgacacttc gaacgacaat ttgaatcata tattcaaaaa aaaaatgaaa aatttgtgcc
    13201 aacaagccta aatattctga aaatttgttt gatttttaat ggataatgtg atataatggt
    13261 tgtcaatcta taattcacat aaacagagga gtagaaaatg aaaaaaaatc gtgtatttgc
    13321 tacagcaggt cttgttttat tagcagcagg tgtacttgca gcatgcagtt cttcaaaatc
    13381 atctgattca tcagccccta aagcttatgg ctatgtttat acagcagacc cagaaacctt
    13441 ggactacctg atttcaagta aaaatagtac aacagtagtg acttcaaatg ggattgatgg
    13501 tttattcact aacgataatt acggtaatct tgctcctgca gttgcagagg attgggaagt
    13561 ctctaaggat ggtttgacct acacttataa gattcgtaaa ggggttaaat ggtttacctc
    13621 tgatggagaa gaatatgcag aggtgacggc taaagatttc gtgaacggtt taaaacacgc
    13681 agcagataaa aaatcagaag ctatgtattt agctgaaaat tcggttaaag gcttggcaga
    13741 ttatctatca ggaacttcaa cagatttttc aacagttggt gtcaaggcgg ttgatgatta
    13801 tacgttacaa tacactttga accagcctga accgttctgg aactctaagt tgacctattc
    13861 tattttctgg cctctgaatg aagaattcga aacatcaaaa ggaagcgatt ttgctaaacc
    13921 aacagatccg acatccttgc tttataatgg tccattcttg ttgaaagggt tgactgcaaa
    13981 atcttctgta gagtttgtaa aaaatgagca atattgggat aaagaaaatg tccacctaga
    14041 tactatcaat ctagcttact atgatggatc agatcaggag tcgctagagc gtaacttcac
    14101 tagtggagct tatagttatg cccgtcttta ccctaccagc tccaactatt ctaaggttgc
    14161 agaagaatac aaggacaata tctattacac acaatcaggc tctgggattg ctggtctggg
    14221 tgtgaatatt gatcgccaaa gttacaacta tacttctaaa actacagatt cagagaaagt
    14281 agctactaag aaggcattgc ttaacaaaga tttccgtcaa gccttgaatt ttgctcttga
    14341 tcgctcagct tactcagctc aaatcaatgg taaagatgga gcagctttag cagttcgtaa
    14401 tttatttgta aaaccagact ttgtttcagc tggtgagaag acctttggtg atttagtcgc
    14461 tgctcaactt cctgcttatg gtgatgagtg gaaaggtgtg aatttagctg atgggcagga
    14521 tggtttattc aatgctgaca aggccaaggc agagtttgcg aaagctaaga aagctttaga
    14581 agcagacggc gttcagtttc ctattcatct ggacgttcca gtagaccaag catcaaaaaa
    14641 ctacatatct cgtattcagt cttttaaaca atctgtagaa acagttcttg gtgttgaaaa
    14701 tgtcgttgtt gatattcaac aaatgacaag tgatgaattc cttaatatta cttactatgc
    14761 tgccaatgct tcatctgagg attgggatgt atcaggagga gtttcatggg gtccagacta
    14821 tcaagaccca tctacttacc tggatatttt aaaaacaaat agcagtgaaa ctacaaaaac
    14881 atatttagga tttgataatc caaatagccc ttcagtagtt caagttggtt tgaaagaata
    14941 cgataaatta gttgatgaag ctgccagaga gacaagcgac ttgaatgtcc gttatgaaaa
    15001 atatgcagcg gctcaagcat ggttgacaga tagttcactc tttattcctg ctatggcttc
    15061 ttctggtgca gcaccagtgc tttcacgaat tgttccattt actggagctt ctgcgcaaac
    15121 aggctctaag gggtcagatg tttacttcaa atatttgaaa ttacaagata aagtggtgac
    15181 taaggaagag tatgaaaaag ctcgtgaaaa atggttgaaa gaaaaagctg aatcaaatga
    15241 gaaagctcaa aaagaattgg caagtcatgt gaagtaaata atttctaata gaactttctc
    15301 tccatgagga gaaggttctt ttgggatttt taaaggaaat aatatgaaaa aatatatttt
    15361 tatgcgtgtt ttgcggtcat tggtttcgat tttcttagta acgactttga cctacacgat
    15421 tatctatacc ttggttcctc gaaaattgat tttcaagcag gatcctaact ataataaaat
    15481 tgcgacaacg gctgataaac gtgataacta tgaaaatact gtgtttgagc gtatgggcta
    15541 cattgagtat tacgatacta aagagttgca agaaaaggca agtagcatgg attcttctgt
    15601 aacagtagaa gcaaatgcga ccaataaagc tatttatgaa aagtacatca atcaattagg
    15661 tcatggttgg actttgggag aatttactga aagtggtcaa ttctatgcta ctcgtgaaat
    15721 tccaattttt gaacgtgttt ttcacttcta tgctaacttg attgacattg accatacaaa
    15781 taaaatccaa gaccctgaaa atccagactt gaaacgctac cttcgttttg aaaatgatcc
    15841 agctatcgga tggtcattgg tcggttcagg aactaaacat aaatatctct tgtactttaa
    15901 cagtcagttc ccatttgttc atcaaaactt tgtgaacttg aatttaggtg actcttaccc
    15961 aacctatgct aatacaccag ttcttcaggt tattactcaa ggtcaaggac aaaccaaaac
    16021 tgcccaagtt cagttcccaa caggtaagaa aacgtcttct gtaaatattt actcaagaac
    16081 ctacaagtca cctagtcagg ctgactctcg tgaagtagct agctatggga aagatgatcc
    16141 ttatacagcg actgaaagta attaccaata tccatctatg attgtcagct ctgctattac
    16201 tggtttgatt ggtttggttc ttgcctatgc tcttgccgtg ccacttggtt cagccatggc
    16261 tcgtttcaag aacacttgga ttgatagcct ctcaacaggg actttgacct tcttgcttgc
    16321 tcttccaacg attgccttgg tttacatcgt tcgattgatt ggatcatcta ttgcccttcc
    16381 agattcattc cctatcttgg gagctggaga ttggcgttct tacgttttac cagcagtcat
    16441 ccttggtttg ttgggtgctc ctgttacagc catttggatt cgtcgttaca tgattgactt
    16501 gcaatctcaa gactttgttc gtttcgctcg tgcaaaaggt ttgtctgaaa aagaaatttc
    16561 aaacaaacac atctttaaaa atgccatggt tccgctggtt tcaggaattc ctggtgccat
    16621 tattggggtt atcggtggtg caacccttac tgaaacagtc ttcgccttcc caggtatggg
    16681 taaaatgttg attgactctg taaaagcatc taataactct atggtcgttg gtcttgtctt
    16741 catctttaca tgtatttcta tcttctcacg tcttttggga gatatttgga tgactattat
    16801 tgacccacgt attaaattga ctgagaaagg aggcaaataa tgtctacaat cgataaagaa
    16861 aaatttcagt ttgtaaaacg tgacgatttt gcctctgaaa ctattgatgc gccagcatat
    16921 tcttactgga aatcagtgtt taaacaattt atgaagaaaa aatcaactgt agtcatgttg
    16981 ggaatcttgg tagccatcat tttgataagt ttcatctacc caatgttttc taagtttgat
    17041 ttcaatgatg tcagcaaggt aaacgacttt agtgttcgtt atatcaagcc aaatgcggag
    17101 cattggttcg gtactgacag taacggtaaa tcgctctttg acggtgtctg gttcggagct
    17161 cgtaactcca tcctcatttc tgtgattgcg acagtgatta acttggttat cggtgttttt
    17221 gtcggtggta tttggggtat ttcaaaatca gttgaccgtg tcatgatgga agtttacaac
    17281 gtcatctcaa acatcccacc tcttttgatt gttattgtct tgacttactc aatcggagct
    17341 ggattctgga atctgatttt tgccatgagc gtaacaacat ggattggtat tgccttcatg
    17401 atccgtgtgc aaatcttgcg ctatcgtgac ttggaataca acttggcgtc acgtactttg
    17461 ggaacaccaa ccttgaagat tgttgtcaaa aatatcatgc ctcaattggt atctgttatt
    17521 gtgacaacca tgactcaaat gcttccaagc tttatctcat acgaagcctt cttgtctttc
    17581 ttcggtcttg gattaccgat tacagtgcca agtttgggtc gtttgatttc ggattattca
    17641 caaaacgtaa caaccaatgc ttacttgttc tggattccat tgacaaccct tgtcttggta
    17701 tccttgtccc ttttcgtagt tggtcaaaac ttagcggatg ctagtgatcc acgtacacat
    17761 agataggagt agaaatgaca aaagaaaaaa atgtaatttt gactgctcgc gatattgtcg
    17821 tggaatttga cgttcgtgac aaagtattga cagccattcg cggcgtttct cttgaactag
    17881 ttgaaggaga agtattagcc ttggtaggtg agtcaggatc aggtaaatct gttttgacaa
    17941 agaccttcac aggtatgctc gaagaaaatg gtcgtattgc ccaaggtagt attgactacc
    18001 gtggtcagga cttgacagct ttatcttctc acaaggattg ggaacaaatt cgtggtgcta
    18061 agattgcgac tatcttccag gacccaatga ctagtttgga ccccattaaa acaattggta
    18121 gtcagattac agaagttatt gtaaaacacc aaggaaaaac agctaaagaa gcgaaagaat
    18181 tggccattga ctacatgaat aaggttggca ttccagacgc agatagacgt tttaatgaat
    18241 acccattcca atattctgga ggaatgcgtc aacgtatcgt tattgctatt gcccttgcct
    18301 gccgacctga tgtcttgatc tgtgatgagc caacaactgc cttggatgta actattcaag
    18361 ctcagattat tgatttgcta aaatctttac aaaacgagta tcatttcaca acaatcttta
    18421 ttacccacga ccttggtgtg gtggcaagta ttgcggataa ggtagcggtt atgtatgcag
    18481 gagaaatcgt tgagtatgga acggttgagg aagtcttcta tgaccctcgc catccatata
    18541 catggagtct cttgtctagc ttgcctcagc ttgctgatga taaaggggat ctttactcaa
    18601 tcccaggaac acctccgtca ctttatactg acctgaaagg ggatgctttt gccttgcgtt
    18661 ctgactacgc aatgcagatt gacttcgaac aaaaagctcc tcaattctca gtatcagaga
    18721 cacattgggc taaaacttgg cttcttcatg aggatgctcc aaaagtagaa aaaccagctg
    18781 tgattgcaaa tctccatgat aagattcgtg aaaaaatggg atttgcccat ctggctgact
    18841 aggaggaagg aaatgtctga aaaattagta gaaatcaaag atttagaaat ttccttcggt
    18901 gaaggaagta agaagtttgt cgcggttaaa aatgctaact tctttatcaa caagggagaa
    18961 actttctcgc ttgtaggtga gtccggtagt gggaaaacaa ctattggtcg tgctatcatc
    19021 ggtctaaatg atacaagtaa tggagatatc atttttgatg gtcaaaagat taatggtaag
    19081 aaatcgcgtg aacaagctgc ggaattgatt cgtcgaatcc agatgatttt ccaagaccct
    19141 gccgcaagtt tgaatgaacg tgcgactgtt gattatatta tttctgaagg tctttacaat
    19201 caccgtttat ttaaggatga agaagaacgt aaagagaaag ttcaaagtat tatccgtgaa
    19261 gtaggtcttc ttgctgagca cttgactcgt taccctcatg aattctcagg cggtcaacgt
    19321 caacgtatcg gtattgcccg tgccttggtc atgcaaccag actttgttat tgcagatgag
    19381 ccaatttcag ccttggacgt ttctgtacgt gcccaagtct tgaacttgct caaaaaattc
    19441 caaaaagagc tcggcttgac ctatctcttc atcgcccatg acttgtcggt tgttcgcttt
    19501 atttcagatc gtatcgcagt tatttacaag ggtgttattg tagaggttgc agaaacagaa
    19561 gaattgttta acaatccaat tcacccatat actcaagcct tgctttcagc agtaccaatc
    19621 ccagatccaa tcttggaacg taagaaggtc ttgaaggttt acgacccaag tcaacacgac
    19681 tatgagactg ataagccatc tatggtagaa atccgtccag gtcactatgt ttgggcgaac
    19741 caagccgaat tggcacgtta tcaaaaagga ctaaactaat aatggtttta taatttccat
    19801 gtcaattttt atggaaatta ggctctttgt caactgtagt gggttgaagt cagctaagct
    19861 cgagaaagga caaatttcgt cctttctttt ttgatgttca aagcgataaa aatccgtttt
    19921 ttgaagtttt caaagtttcg aaaaccaaag gcattgcgct tgataagttt gatgagatta
    19981 ttggtcgctt ccagtttggc attagaatag tgtagttgaa gggcgttgat aatcttttct
    20041 ttatctttga ggaaggtttt aaagacagtc tgaaaaatag gatgaacctg cttaagattg
    20101 tcctcgataa gttcgaaaaa tttctctggt tccttattct ggaagtgaaa aagcaagagc
    20161 tgatagagct gatagtggtg tttcaagtct tgtgaataac tcaaaagctt gtttaaaatc
    20221 tctttattgg ttaagtgcat acgaaaagta ggacgataaa atcgcttatc actcagttta
    20281 cggctatcct gttgtatgag cttccagtag cgcttgatag ccttgtattc atgggatttt
    20341 cgatgaaact gattcatgat ttggacacgc acacgactca tagcacggct aagatgttgt
    20401 acaatgtgaa agcgatcaag aacgatttta gcattcggga gtgaaacagt ctagaagact
    20461 gtttcagcct gagcctagaa atttgaaagc gaagctgttt agccaagtca tagtaagggc
    20521 taaacatatc catagtaatg attttgacgc gacatcggac ggctctatca tatttaagaa
    20581 agtgatctcg gatgacagct tgtgttctac cttcaagaac agtgatgata tcgagctttt
    20641 caaaatcttg cgcaataaag ctcatctcca tctcccgatt gaaacagtca ctccccggac
    20701 tgtttcaacg tcccaagaca taatcttagg cagatttcta aaattacact caaagtggaa
    20761 gtcattgagc tttcgaatga cagttgaagt tgagatggaa agctgatggg caatatcagt
    20821 catagaaatc ttttcaatta acttttgagc aatcttttgg ttgatgatac gagggatttg
    20881 atgattcttc ttgacgatag aagtttcagc aaccataatt ttagaacaat gatagcactt
    20941 gaaacgacgc tttctaagga gaattctagt aggcatacca gtcgtttcaa gataaggaat
    21001 tttagaaggt ttttgaaagt catatttctt catttgactt ccgcactcag gacaagatgg
    21061 agcttcatag tccagtttgg cgatgatttc cttgtgtgta tccttattga tgatgtctaa
    21121 aatctggata ttagggtctt taatgtctag taattttgtg ataaaatgta attgttccat
    21181 atgaatcttt ctaatgagtt gttttgtcgc ttttcattat aggtcatatg ggactttttt
    21241 tctacacaaa ataggctcca taatatccat aggggggtta cccactacaa atattataga
    21301 gccgaaaaag gctgagatct ggtgtctcag tcttttattt cttgcgtttt gcaaaatcta
    21361 caaatctaaa tttttctaac ttatggcgac tttcggtaaa ctgaaattgg cgtccgtctt
    21421 ggagatagac ttttgattta atcgaaacga cataagggtc tttgccaatg tccatgagaa
    21481 tcttgtctcg gtcgcttgag tggtcaatgg tgatttcctt ctgagcataa tcaataagga
    21541 gtttgaggcc attttctata taagaataga tagactgctc agcaatttgg cgagtgagat
    21601 ttggaattag ttccatatcc agatagtctg tatccagaac ggataccaga tcatccacca
    21661 cacgctggcg gaccaccttc caaaccatcc gaaactctgg gaaaccggtt atcagtgagg
    21721 attttttatc aataataatc ttgtccagac tgaccacgtt ggttttagag cgcagtccaa
    21781 gttctttaac tagttcttgg tagctggtta ggttggatac agggaaattg acggtttctt
    21841 ctttgacgac ttgagaacct tgccctctta tctttttgat caatccttcc tcttggagga
    21901 gagacagggc ctttcggacg gtatcacgac tcacttgata ttgctccata aggtcgtgct
    21961 cgctaggaag gaaatctccg acagcgtaag tctcgttttg aatggtttct tggatttgct
    22021 taaataattg ttggtatttc ttcattttgc ctgcttaaat aggtttttag tctagtttaa
    22081 tgaacacctg tatctatttt accatacaag tgctagaaaa tttacaaaaa aacacccttt
    22141 ttataccaaa caagttgcag acaagtttgg tatcgtttac aatatactta tcaaatcaaa
    22201 cttgctttga caagtataag gagaatcaaa tgggaaaatt tgaacaagaa gccaaagatc
    22261 tgcttcaggc aattggaggc aaagaaaatg tgactgccgt cacccactgt gcgacacgga
    22321 tgcgctttgt tttaggagat gataagaagg ctaatgttaa agctatcgag tcaattccag
    22381 ctgttaaagg aacttttaca aatgcaggtc aatttcaggt aatcattgga aatgacgtgc
    22441 ccatctttta taatgatttt acagccgttt caggtattga gggtgtttcc aaagaagcag
    22501 ccaagtctgc agctaagagt aatcaaaacg tggtccaacg tgttatgacc actctggcgg
    22561 agatttttac tccgattatt ccagccttga tagtcggagg attgatcctc ggtttccgta
    22621 atgtcttgga aggtgtccat tggtcgatgt tggatggcaa gaccatcaca gaatcctctc
    22681 agttttgggc aggtgtcaat cacttcctct ggttgcctgg tgaagctatc ttccagttct
    22741 taccagtagg gattacttgg tctgtttctc gtaagatggg aaccagccaa attttgggaa
    22801 ttgttctcgg aatctgtttg gtatcgcctc agttgctcaa tgcctatgcg gttgcttcaa
    22861 cgccagcagc tgatatcgcg gcaaactggg tttggaattt tggctatttt actgttaatc
    22921 gtatcggtta ccaagcccaa gttatcccag ccttgcttgc aggtttgagt ctgtcttatc
    22981 ttgaaatctt ctggcgcaag catatcccag aagtcatttc tatgattttt gtacctttct
    23041 tgtcattgat tccagccttg attttggctc atactgtttt gggaccaatc ggttggacaa
    23101 ttggacaagg actttcatca gttgtcttgg caggtttaac tggtccagtt aaatggctct
    23161 tcggtgcaat ttttggtgcc ctctacgctc catttgtcat cacaggtctg caccatatga
    23221 ccaatgccat tgatacacaa ttgattgcgg atgctggtgg cactgcccta tggccaatga
    23281 ttgctctttc taatattgct caaggctcag ccgtgtttgc ctattatttc atgcatcgcc
    23341 atgatgagcg tgaggctcag gtttcacttc ctgcaaccat ttcagcctat ctcggtgtta
    23401 cagaaccagc tctttttggg gttaacgtaa aatatattta tccatttgtt gctgggatga
    23461 ctggttcagc ccttgcaggc atgttatccg ttacttttaa tgtaactgcg gcttctattg
    23521 gtatcggtgg tttgccaggt attctctcta ttcaacctca atacatgctg ccatttgcag
    23581 gaactatgct agttgcgatt gttgttccaa tgctcttgac tttcttcttc cgcaaggctg
    23641 gtctctttac aaaaacagag ggcgatacga acttgcaggc agaattcgtt gctcaagaag
    23701 aagcagaatt tgtgaaccat gaaccagtag aacttacttc ggtagaaatt atcagcccac
    23761 taactggcca agtgaaagaa ttgagtcaag cgacggatcc tatttttgca tcaggtgtca
    23821 tggggcaagg tctagtcatt gaaccaagcc aaggtgagtt gacctctcca gttaatggga
    23881 cagtgacggt tcttttccct accaagcatg ccatcggcat tgtctctgac gagggagttg
    23941 aattgctcat ccacatcggt atggatacag taggtcttga tggcaaaggt tttgaaagtc
    24001 ttgtagtcca aggagatcac gttacagttg gtcagcaact gattcgtttt gatatggatg
    24061 tcattaaggc tgcaggtctg gtgacagaaa ctcctgttat catcaccaac caagatgctt
    24121 atacagcgac tattcccgga acttatccga caacgatcca agctggagca tctctcatgg
    24181 tcgctacacg aatctaatac tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca
    24241 acctcaaaat agtgttttga gcaacctgtg gctagcttcc tagtttgttc tttgattttc
    24301 attgagtata attgaaatag cacaaatagg gacggaagac tgcttcctcc cttttatcag
    24361 aaaaggagaa acagatgaca cttgataaag gaaaagtagt ctatcaaatc tatccaaaat
    24421 cttacaaaga caccactgaa aacggtattg gggatttccg tgggattatc gaaaaaattc
    24481 cctatttagc caaactaggt gtggatatgg tctggctcaa tccattctat ccaagccctc
    24541 aacgggataa tggttacgat atttcagatt atatggcagt ggatcctctt tttggtgata
    24601 tggctgattt tgaggaaatg gtgtgtgtcg gtaaagagca caagattgac tttatgctgg
    24661 acatggtact taatcattgt tcgacagagc atgaatggtt tcagaaagcc ctagctggtg
    24721 ataagtatta tcaagacttt ttcttcatcc aagaccaacc aacagattgg cagtctaagt
    24781 ttggtggttc tgcatggacg cctttcgggg atactgggaa atactatctt cacctatttg
    24841 atgagaccca ggctgacctt aactggcgca attccaatgt ccgtaaggag cttttcaagg
    24901 ttgttaattt ctggcgcgac aagggtatca aaggtttccg atttgatgtg atcaatttga
    24961 tcggtaagga cgaggtttca gtggactgtc ctgaaaatga agggaagcca gcttatacag
    25021 acaaacccat cgttcataac tatttgcgta tgatgaacca agccactttt ggatctgacg
    25081 atagctttat gacagttggg gaaatgtctt ctaccaccat ggaaaactgt gtcctctatt
    25141 cgtcgcctga tcgtcaggaa ttatccatga cctttaattt tcatcacctc aaggtggact
    25201 ataaggatgg acaaaagtgg accttggctc cctttgattt tgaagagttg aagagtcttt
    25261 accatagttg gggtaaggaa atgagtgata aagacggttg gagtgccctc ttttggaaca
    25321 atcacgatca accacgtgcc ttgaaccgtt ttgtcgatat tcaaaacttc cgcaaggaag
    25381 gagccaccat gctagcggct agcattcacc tgtcacgtgg gacaccttat atctatatgg
    25441 gtgaagaaat cgggatgatt gacccagact atgattctat ggctgattat gtggatgtcg
    25501 aatcgcttaa tgcctatcag acgctcttag aagaaggaaa gagtcagcaa gaagccttcc
    25561 agattattca agctaagtcg cgtgataatt cacgcattcc catgcagtgg gatgcttcgg
    25621 aaaatgcagg attttcaaca ggcactccat ggttgaaagc tggtaaatcc tataaataca
    25681 tcaatgtaga aaatgaaatc cagggtccga ttttcacctt ctatcaagac ttgattcgac
    25741 tgcgtaagga aatgccaatc atttcagaag gaagttacaa accagccttt gaagatagca
    25801 aacaagtcta cgcttttgaa cgccagtttg aggatcaaaa gttactagtg ctcaataact
    25861 tttatgctaa agaagtggaa atcgacttgc cagcagtcta ccaaaatgga cagattttga
    25921 tatcaaacta tgaagatgca gaagtgtctg agaaaattct actcaaaccc tatcaaacac
    25981 tggctattta tgtaaattaa tactcttcga aaatctcttc aaaccgtgtc agttttatct
    26041 gcaacctcaa agcggtgctt tgagcaacct gtggctagct tcctagtttg ctctttgatt
    26101 ttcattgagt ataaacttag caaggagacc tctttttcag aaaagcagcg ttctttttgc
    26161 tgtctattcc atccctgaaa gtgtagaaca aactggtcag ggtggctagt ttgtggtata
    26221 atgaaaggga ttcaaaaaga aacaggagaa aaatgatgga tttactttta gcaattgtat
    26281 tgattgtgct agcttttcta ggaggagctc ttggaggaat gtacttggtt cgtaagcaaa
    26341 tcgaaaaaga atttgctgac aacccacgtt tgaatgctga agcagttcgt actcttttga
    26401 gtgcaaatgg tcaaaaacca agcgaagcta aggtacaaca agtttaccac caaatcatcc
    26461 gccaacaaaa ggcagccctt gctaacaata aaaagaaaaa ataaataagg aaaagtctgg
    26521 gatgaaagtt ccagacttct cactatgttg gttatggttt agggatgaga ctttttcctt
    26581 gcattctatt gatatttgat tatgattaag agagaggtag ttgacattct atcaagctgt
    26641 cggtcagttc gttcagtaca aggaatcata atgaacgatc aatcagaaaa aagactagaa
    26701 agaagactgt atggataatc gaccaattgg ttttttggat tcgggtgtcg ggggcttgac
    26761 cgttgtgcgc gagctcatgc gccagcttcc ccatgaagaa atcgtctata ttggagattc
    26821 ggcgcgggcg ccctatggcc cccgtcctgc tgagcaaatt cgtgaatata cttggcagct
    26881 ggtcaacttt ctcttgacca aggatgtcaa aatgattgtc attgcttgta acactgcgac
    26941 tgcggtcgtc tgggaagaaa tcaaggctca actagatatt cctgtcttgg gtgtaatttt
    27001 gccaggagct tcggcagcca tcaagtccag tcaaggtggg aaaatcggag tgattggaac
    27061 gcccatgacg gtacaatcag acatataccg tcagaaaatc catgatctgg atcccgactt
    27121 acaggtggag agcttggcct gtcccaagtt tgctcccttg gttgagtcag gtgccctgtc
    27181 aaccagtgtt accaagaagg tggtctatga aaccctgcgt cccttggttg gaaaggtgga
    27241 tagcctgatt ttgggctgta ctcattatcc actccttcgc cctattatcc aaaatgtgat
    27301 ggggccaaag gttcagctca tcgatagtgg ggcagagtgc gtacgggata tctcagtctt
    27361 actcaattat tttgaaatca atcgtggtcg cgatgctgga ccactccatc accgttttta
    27421 cacaacagcc agtagccaaa gttttgcaca aattggtgaa gaatggctgg aaaaagagat
    27481 tcatgtggag catgtagaat tatgacaaat aaaatttatg aatataagga tgaccaggac
    27541 tggtatgttg ggtcttatag tatttttggt ggcgttaaca gtttgagcga ctatcagaca
    27601 gattttcctc tgtttgaatt ctccaaaata tttggagatg aagagtatgg tttcccgctt
    27661 tcagttactg ttttacgcta tggttctacc taccgtttgt tctcctttgt ggtagatatg
    27721 cttaatcaag aaatgggacg aaacttggaa gttattcaac gtcatggggc cctgctcttg
    27781 gttgaaaatg ggcaactctt gtatgtagaa ttgcctaaag aaggggtcaa tgttcatgat
    27841 ttctttgaga caagcaaggt cagagaaacc ttgttgattg cgactcgtaa cgaaggtaaa
    27901 accaaggaat tccgagctat ctttgataag ttaggctacg atgtggaaaa tcttaatgac
    27961 taccctgacc tgcctgaagt agcagaaaca ggtatgacct ttgaagaaaa tgcccgcctt
    28021 aaggcagaaa ccatttctca attaacgggc aagatggttt tggcagatga ttctggtctc
    28081 aaagtcgatg tccttggtgg cttaccaggc gtctggtcag ctcgtttcgc aggtgtggga
    28141 gcaactgacc gtgaaaataa tgccaaactc ttgcacgaat tggccatggt ctttgaactc
    28201 aaggaccgct cggctcagtt ccacacaacc ctagtcgtag ccagcccaaa taaggaaagt
    28261 ttagttgttg aagcagactg gtcaggttat attaactttg aacctaaggg tgaaaatggc
    28321 tttggctatg atcccctctt ccttgtagga gagacaggtg agtcatcagc tgaattaacc
    28381 ctggaagaaa aaaatagtca atctcaccgt gccttagccg ttaagaaact tttggaggta
    28441 tttccatcat ggcaaagcaa accatcattg taatgagcga ttcccatggc gatagcttga
    28501 ttgtggaaga agtccgtgat cgctatgtgg gcaaagtcga tgccgttttt cataacggcg
    28561 attctgaact acgtccggat tctccacttt gggagggcat ccgcgttgtt aaagggaaca
    28621 tggacttcta cgccggctac ccagaacgtc tggtgactga gcttggttcg accaagatta
    28681 tccaaactca tggtcacttg tttgacatca atttcaactt tcaaaagttg gactactggg
    28741 ctcaggagga agaggccgct atctgcctct atggtcactt gcatgtgcca agtgcttgga
    28801 tggaaggcaa gatcctcttt ctaaatccag gttctatcag ccaaccacga ggtaccatca
    28861 gagaatgtct ctatgctcgt gtggagattg atgatagtta cttcaaagtg gactttttga
    28921 cacgagatca cgaggtgtat ccaggtttgt ccaaggagtt tagccgatga ttgccaagga
    28981 gtttgagact ttcttgttgg ggcaggagga aacttttttg acccctgcta aaaatctagc
    29041 tgtgttgatt gatacccaca atgcggatca tgcgaccctc ttgctcagtc agatgaccta
    29101 tacccgtgtt cccgttgtga cagatgaaaa acagtttgtt gggacgattg gactcagaga
    29161 tattatggct tatcagatgg agcatgactt gagccaagaa atcatggcgg atacggatat
    29221 cgttcatatg acaaaaacgg acgtagcggt tgtttcgcct gatttcacca ttacggaggt
    29281 cttgcacaag ctagtagatg agtccttctt accggttgtg gatgcagagg gtattttcca
    29341 agggattatt acgcgcaagt ccatcctcaa ggccgttaat gccctcttgc atgactttag
    29401 taaggaatat gagattcgat gccaatgaga gacaggattt cagccttttt agaggaaaag
    29461 cagggcttgt ctgtcaattc caagcagtcc tataagtatg atttggagca atttttagac
    29521 atggtaggtg agcggatttc tgagaccagt ctcaagattt accaagccca gctagccaat
    29581 ctaaaaatca gcgcccagaa gcgaaagatt tcggcctgta accaatttct ctactttctc
    29641 tatcaaaaag gagaggtgga cagcttttac cgcttggaat tagccaaaca agctgaaaag
    29701 aagacggaaa agccagagat tctataccta gactcttttt ggcaggaaag cgaccatcca
    29761 gagggccgct tgctagcgct cttaatccta gaaatggggc tcttgcccag tgagatttta
    29821 gccatcaagg ttgcggacat caatctggat tttcaggtgc tgcgaatcag caaggcttcc
    29881 caacagagga ttgtcaccat tcccacggcc ttgctttcag aattggaacc cttgatgggg
    29941 cagacctatc tttttgaaag aggagggaaa ccctattctc gtcagtgggc ctttcgtcag
    30001 ttagaatctt ttgtcaagga gaaaggtttt ccatccttat cagctcaagt cttacgtgaa
    30061 cagtttattc taagacaaat agaaaacaag gtcgatttgt acgaaattgc aaaaaaatta
    30121 ggattaaaaa cagtcctgac cttagaaaaa tatagataat ggatattaaa ttaaaagatt
    30181 ttgaaggacc cctggactta ctcttgcatc tggtttctaa gtaccagatg gatatctacg
    30241 atgtgcccat tacggaagtc atcgaacagt atctagccta tgtctcaacc ctgcaggcca
    30301 tgcgtctgga agtgacgggt gagtacatgg tcatggctag tcagctcatg ctgattaaga
    30361 gtcgtaaact ccttccgaag gtagcagaag tgacagactt gggggatgac ctggagcagg
    30421 acctcctctc tcaaatcgaa gaatatcgca agttcaagct cttgggtgag cacttggaag
    30481 ccaagcacca agaacgggcc cagtattatt ccaaagcgcc gacagagttg atttacgaag
    30541 atgcggagct tgtgcatgac aagacgacca ttgacctctt tttgactttt tcaaatatcc
    30601 tagccaagaa aaaagaggag tttgcacaaa atcacacgac gatcttgcgg gatgagtata
    30661 agattgagga catgatgatt atcgtgaaag agtccttgat tggacgagat caattgcgct
    30721 tgcaggattt gttcaaggaa gcccagaatg tccaagaggt catcaccctc tttttggcaa
    30781 ccctagagtt aatcaaaacc caggagttga tcctcgtgca agaggagagt tttggagata
    30841 tctatctcat ggaaaagaag gaagaaagtc aagtgcctca aagctagact tgatagagag
    30901 gaaagatgag tactttagca aaaatagaag cgctcttgtt tgtagcgggt gaagatggga
    30961 ttcgggtccg ccagttagct gaactcctct ctctgccacc gacaggcatc cagcaaagtt
    31021 taggaaaatt agcccagaag tatgaaaagg acccagattc cagtttggct ttgattgaga
    31081 caagtggtgc ttatagattg gtgaccaagc ctcaatttgc agagattttg aaggaatact
    31141 ctaaggcgcc tatcaaccag agcttgtctc gggctgccct tgagaccttg tccattattg
    31201 cctacaaaca gccgattacg cggatagaaa ttgatgccat ccgtggagtt aactcgagtg
    31261 gagccttggc aaagttgcag gcttttgacc tgataaagga agacgggaaa aaggaagtat
    31321 tggggcgccc caacctctat gtgactacgg attatttcct agattacatg gggataaacc
    31381 atttagaaga attaccagtg attgatgagc ttgagattca agcccaagaa agccaattat
    31441 ttggtgaaag gatagaagaa gatgagaatc aataagtata ttgcccacgc aggtgtggcc
    31501 agtaggagaa aagcagaaga gctgattaag caaggcttgg tgacggttaa cggccaagtg
    31561 gtgcgtgaac tagcaaccac tatcaagtca ggcgacaagg tcgaagttga aggtcaacct
    31621 atctacaacg aagaaaaggt ctactatctg cttaacaaac cacgcggtgt gatttccagt
    31681 gtgacagatg ataagggtcg caagacggtt gtcgacctct tgcccaatgt caaagagcgt
    31741 atttaccctg tgggtcgttt ggactgggat acatcaggtg tcttgatttt gaccaatgat
    31801 ggggacttta cagacgagat gattcaccct cgtaatgaga ttgacaaggt ttatgtcgcg
    31861 cgtgttaaag gtgtggccaa taaggacaat ctccgcccct tgacccgtgg tcttgagatt
    31921 gatggtaaga aaaccaagcc agctgtttat gaaattctca aagtggaccc agtcaaaaat
    31981 cgctctgtgg tgcagttgac catccatgaa gggcgtaacc atcaggttaa aaagatgttt
    32041 gaagctgttg gtctccaagt agataagttg tctcggactc gtttcggaca cctagacttg
    32101 acaggactcc gtccaggaga atcccgtcgt cttaataaaa aagaaatcag ccaactacac
    32161 accatggctg taactaagaa ataatgaaac gaattttaat agcgcctgtg cgcttttacc
    32221 aacgttttat ctcaccagtc tttccaccct cttgtcgctt tgagctgact tgttccaact
    32281 acatgattca ggctattgaa aaacatggtt ttaagggggt attgatgggc ttggctcgga
    32341 ttttacgttg tcatccctgg tcgaaaacag gtaaggaccc cgttccagac cacttttccc
    32401 ttaaacgaaa tcaagaaggg gaatgaggtg gggtaaatag atttcaaaat gataaaaacg
    32461 catcctatca ggtttgagtg aacttgatag gatgcgtttt agaatgtcaa aattttatac
    32521 tcttcgaaaa tcccttcaaa ccgcgtcagc tttcatctgc aacctcaaaa cagtgttttg
    32581 agcaacctgc ggctagtttc ctagtttgct ctttgatttt cattgagtat taaattgagt
    32641 ttgaagtggc ttatttcaaa gctttttgta tgtcttcaat catgagtttt gttgattcaa
    32701 gtccgcctcc gcttagatac cagaggtctg gtgttagttg gataatctta ccatttttag
    32761 cagcaggtgt ttcagcgata agggcatttt ctaggacacc gtcgttgcta gagttgtccc
    32821 caccgatggc aagggtacgg ttgatgacaa agaggatgtc agggttgatt tctttgacac
    32881 tttcaaagct gacttcttgt ccgtggcgtg agtcttcaaa ttttgtatca gttggtttga
    32941 atttcaaggt ttggtacaag aaagagaaac gagatttggc accaaaggct gccatttttc
    33001 cttcattaag gaggatcgta agggcttttt tgtcagagct ttcattttta gtagcgactt
    33061 cttggatgct cttgtctagc ttggccaatt cttccttggc tttctgtgta ccagtttcgc
    33121 cgaaggcact tgctaaggat tcgatattag ccttggtaga agtccagtag tcgtccttgc
    33181 ttgcttggaa gagaacggtt ggggcgattt ctttgaattt gtctacgaat ttttgtgtac
    33241 gtggtgaagc gataatcaaa tcaggctcaa gggcggcgat agcttctaaa tcaggttctt
    33301 tcatagaacc aacatttttg acagttccca ctaggtcttt tagataagtc ggaacagttt
    33361 ttgtaggcat tccgacgata tttttttcaa atcctaaagc gcgaatagta tccgcagcgc
    33421 cgaggtcaaa ggtcacaatc ttttcaggaa ctttggaaag tttgacctcg tccagtgaac
    33481 ttttaatggt tatctctgtt ggagcagagc tactggtctc tgtctgacta gtgcttgagt
    33541 ttgtactaca tgcaccaagt aggagcaaga agctggccac tagggcagtg aaataaagtt
    33601 taagggatgt tttcataatt tttccttttt aaaatgtgat aacgatttag ggagtctctt
    33661 aatcttattg actaagagac tgaaggttct ctaacttgag cttttatgtt actagctata
    33721 gatacagatc tttttgtcat tgatatcagc tagcgtgatg ggaatctcat aaagttgact
    33781 gagcaggtca gcctgcatga tttgatcggt tcttcccttg ctaaagacct ggccgtcctt
    33841 gaaggcgaca atttcatctg catactgact ggccatgttg atatcgtgga ggacgatgat
    33901 aatggtcttg ccgagttcct ccaccagtcg tcgaagaatc tgcatcatgc tgacgctttg
    33961 cttgatatcg agattgttga gtggttcgtc cagcaagata aagtccgtat cctgggccag
    34021 taccatagcg ataaagacgc gctggagttg cccccctgac aggctattga tgtagcggtc
    34081 ttttaagttg gtcagttcca aatagttcag agtttctcgg attttttccc agtcttctga
    34141 tctaagtcga cctcggctgt agggaaaacg tccaaaactg accagttctt caacagtcaa
    34201 tttggcttgg taattgattt tctgttttag gatggttagt tcttgggcca gttcttgcga
    34261 attccagctc tcgatttcac gtcctttgat actgagaact ccctgatctt tcttggttag
    34321 tctgctcatg atggagagga gagtcgattt tccagcacca tttggaccaa taaaggctgt
    34381 cagtttttga ggactgactt caagcgaaat gccttgcaaa atatcctgtt tttgaatgga
    34441 tttgtcaatg ttttccagtt tcactgacga gccctcctat atagtaagat aaagaataag
    34501 aagccaccca cactctcaat gatcatactg atacgaattt ccagtgcaaa gactcgttca
    34561 atcaaggctt gccccaaggt taagctaata aatccaacca gaatggccac tataaagagt
    34621 aacttgtgct gatagtcttt gacaatcagg taggtgaggt tggccagcat aaagccgaag
    34681 aaggccatag gtcctaccaa ggcagtggcc gttgaggtca aaagcacgat tccccagagg
    34741 agctctttct gttctttttc aacatcgagt cccaatatct gagccgtttc tctttgcagg
    34801 tgcaagacat ctagaacgac tgcttttcga aagaaaaaga ttgtcaaagc gaggatgatc
    34861 agagaaccga tggctaggat ggaagtgttg agatgttgaa aggaggcaaa aagactattt
    34921 tgcagtttat cgtattcgtt tggatccatt aggacttgaa ggaaggtgct gatatttcga
    34981 aagagacttc tgagcgctag acagatcagc aggatgaaga ccaggtcttg cttcatcagt
    35041 gtcttcaagt aaccttgtaa ggcgagaaag aagagggact ggacaagaag taagactagg
    35101 aattctaaga taggggattt gccaagttga agaaacttgc tttcaaaaac cagtagtagg
    35161 gtttgtagta ggacgtagaa ggattcaatt cccaaaatac taggcgtcag gaagcgattt
    35221 tccgtcaggg tttgaaaact aatggtcgaa atcccagtcg cgatggctac caagagataa
    35281 acgatgatct tttgggaacg caacttccaa gcaaaggctg acaagtgagt gatgggccaa
    35341 aagtagagaa gacaagctcc gatggcaaga ataatgagaa tccagaagag cttggtatgt
    35401 ttgcttttag tctgcatctt ttcgtccccc tctccagaga agtaggataa agacgagact
    35461 accgatgatt cctagcaaga gactgacaga caactcatag ggcctaatca gaactcggga
    35521 taggatatcg caagccagaa ctagattggc accaaccagt gcgaccatga gtttggtttg
    35581 acttagatta tctccatagc gcttgcgaac aagattggga acgataactc cgagaaatgg
    35641 taagccaccc acggtaatca tggtgacgct tgtcgttagc gccaccagaa agagggccag
    35701 tttttcaagt agggagtagg aaatccccaa actctcgctg gtttctttcc ctagattcat
    35761 gatggtgaag gtttgggata atttccaaac ggttatcagg atgatgaggc ctaagaagag
    35821 ccactcatac tgatgggtct gaatcatgga gaaggagccc tgggtccagg cagtcatact
    35881 ctgaaccaga ttgaaacgat aggcgataac ttctgtgact gagccgataa tcccgctata
    35941 gatgatccca atcagaggca acatccacct ttcctttaca gtaaaaatgg tcataaaggc
    36001 taggaagaag agggtgaata cgatggatga aacaaaagcg aagagcatct tttgggtcag
    36061 actagccgat ggaaagacaa aaaggctcag caccattccc agtttggcgg cttcagtcgt
    36121 tccaactgta ctcggtgcag caaactgatt ttgggtaata gtctgcatga gaaggcctgc
    36181 catactcata ctagaggcag tcaggagaat actgatagtt cttgggagac gggactcttg
    36241 aaagaggagc caggtctgct ggtcgaaatc aaatagcttt ccccatgaaa aatcactggt
    36301 cccaatgcta atagagagaa agactaggag tagaagtaag ccaattaaat aatgagaaag
    36361 tttcataccc cgtcctttca tgtagatttg gtatcgaaag atatctgcgg atataaatgt
    36421 aacattattt ttctaatctg tcaataaaat ttctgacaat ttaataaata caacaaggag
    36481 agagcaacaa gattttctcc tttgttatcc tattctaaaa tgtttttacc ttaatctgat
    36541 aaaataatat cttcgaggga gtagctagcc gtccaatcaa gatattgttt agcttttgaa
    36601 gcatctgcta ggacactggc tgggtcacta gcacgtcgag caacaatctc gtgtgggatt
    36661 ttttaattta gtaattcttc agcagtttta aagatttctt tgatagtata gtctttttta
    36721 gttcctaagt taaagatttg agaagaactg tcttcttgaa ataggtagtt cattccttta
    36781 acatgagcct atgcaaggtc caagacataa atgtaatctc gaatacatga atcgtcacgt
    36841 gtatcgtagt catctccaaa tatttttaag ctatcatgtt gtcccaatgc ggtcttgttg
    36901 atatttggaa tgatgtgagt tggatttttc acacgcagac cgtttgaagc atccatttca
    36961 gccccagcaa cattaaagta acggaaaata acatatttcc agtcgtagcg attggccatc
    37021 cagtaaatca ttcgttcgcc catcagtttt gtctctgcat aagggttgac agggtcgagc
    37081 agggtatctt cagtcaccgg cttgtcaata cagttatttc catagagaga agcagtcgaa
    37141 gagaacatga ttttttgaat gccaacttca gataagactt tgagaacttg gttcatacca
    37201 gcaacgttgg cagtgaagta tttacttgga ttttcaatac tttcgctcac aacaatttca
    37261 cctgcacaat ggaggacagc atcaatctga ttttcttcta agtaagcctt taaggcgcta
    37321 gcatcataaa catccagttc tttaaagcta gcacgactat ccacagccgc tcgatttcct
    37381 gtggagagat tatcgaggac atgcacctga tagccagcat ttaaaagagc tttaacggta
    37441 tgggagccaa tgtagctagt cccacctgta acaagaattg ttttggtcat gattttttcc
    37501 ttttctagtt ttgtactata gta
//
LOCUS       DAVKMO010000015        36746 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVKMO010000015 DAVKMO010000000
VERSION     DAVKMO010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36746
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.015"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(261..971)
                     /locus_tag="VW361_000883"
     CDS             complement(261..971)
                     /locus_tag="VW361_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU9743952.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(974..2665)
                     /locus_tag="VW361_000884"
     CDS             complement(974..2665)
                     /locus_tag="VW361_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9743953.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(2677..3687)
                     /locus_tag="VW361_000885"
     CDS             complement(2677..3687)
                     /locus_tag="VW361_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743954.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(3791..4858)
                     /locus_tag="VW361_000886"
     CDS             complement(3791..4858)
                     /locus_tag="VW361_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9743955.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(4883..5542)
                     /locus_tag="VW361_000887"
     CDS             complement(4883..5542)
                     /locus_tag="VW361_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU9743956.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIYMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            complement(5751..6035)
                     /locus_tag="VW361_000888"
                     /pseudo
     CDS             complement(5751..6035)
                     /locus_tag="VW361_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(6283..6579)
                     /locus_tag="VW361_000889"
     CDS             complement(6283..6579)
                     /locus_tag="VW361_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9743957.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(6563..8722)
                     /gene="pfbA"
                     /locus_tag="VW361_000890"
     CDS             complement(6563..8722)
                     /gene="pfbA"
                     /locus_tag="VW361_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU9743958.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGYGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(9852..11078)
                     /locus_tag="VW361_000891"
     CDS             complement(9852..11078)
                     /locus_tag="VW361_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU9743959.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(11121..11813)
                     /locus_tag="VW361_000892"
     CDS             complement(11121..11813)
                     /locus_tag="VW361_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU9743960.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(11986..13737)
                     /locus_tag="VW361_000893"
     CDS             complement(11986..13737)
                     /locus_tag="VW361_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743961.1"
                     /translation="MQNKQEQWTVLKRLMSYLKPYGLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLAYANRSVALDALFLRPAMSLLKLLGYAVLMTYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALIDERTYEPLQENGQA
                     KVKEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(13727..15472)
                     /locus_tag="VW361_000894"
     CDS             complement(13727..15472)
                     /locus_tag="VW361_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9743962.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYTTSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLLAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGTI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADLILVLQNGQIIERGRHEDLLALDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(15678..16130)
                     /locus_tag="VW361_000895"
     CDS             complement(15678..16130)
                     /locus_tag="VW361_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU9743963.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(16127..16583)
                     /locus_tag="VW361_000896"
                     /pseudo
     CDS             complement(16127..16583)
                     /locus_tag="VW361_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            16717..17544
                     /gene="xth"
                     /locus_tag="VW361_000897"
     CDS             16717..17544
                     /gene="xth"
                     /locus_tag="VW361_000897"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU9743964.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHLEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            17556..17807
                     /locus_tag="VW361_000898"
     CDS             17556..17807
                     /locus_tag="VW361_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU9743965.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLSL
                     EECQLMLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLY"
     gene            17814..17942
                     /locus_tag="VW361_000899"
     CDS             17814..17942
                     /locus_tag="VW361_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HEU9743966.1"
                     /translation="MKANYPIYRLLTKRKFRVSDPYIYPHKFAVLDPNGYFLRFSE"
     regulatory      18325..18420
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18771..19352
                     /locus_tag="VW361_000900"
     CDS             18771..19352
                     /locus_tag="VW361_000900"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU9743967.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            19352..20614
                     /locus_tag="VW361_000901"
     CDS             19352..20614
                     /locus_tag="VW361_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU9743968.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKIANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPIP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(20664..21125)
                     /locus_tag="VW361_000902"
     CDS             complement(20664..21125)
                     /locus_tag="VW361_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEU9743969.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(21122..21886)
                     /locus_tag="VW361_000903"
     CDS             complement(21122..21886)
                     /locus_tag="VW361_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU9743970.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYCPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCDIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(22067..22471)
                     /locus_tag="VW361_000904"
     CDS             complement(22067..22471)
                     /locus_tag="VW361_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU9743971.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVSI"
     gene            complement(22541..24022)
                     /locus_tag="VW361_000905"
     CDS             complement(22541..24022)
                     /locus_tag="VW361_000905"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU9743972.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYVHSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKTL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(24041..25219)
                     /locus_tag="VW361_000906"
     CDS             complement(24041..25219)
                     /locus_tag="VW361_000906"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU9743973.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLERDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYKEVVGYAPSFYIAEVAGGTRVFD
                     "
     gene            25384..26391
                     /gene="galR"
                     /locus_tag="VW361_000907"
     CDS             25384..26391
                     /gene="galR"
                     /locus_tag="VW361_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU9743974.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(26437..27474)
                     /locus_tag="VW361_000908"
     CDS             complement(26437..27474)
                     /locus_tag="VW361_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9743975.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKVGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(27475..27828)
                     /locus_tag="VW361_000909"
     CDS             complement(27475..27828)
                     /locus_tag="VW361_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU9743976.1"
                     /translation="MNIKSASDLLEISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQIQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(28072..28962)
                     /locus_tag="VW361_000910"
     CDS             complement(28072..28962)
                     /locus_tag="VW361_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU9743977.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            29095..29631
                     /locus_tag="VW361_000911"
     CDS             29095..29631
                     /locus_tag="VW361_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9743978.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(29798..30604)
                     /locus_tag="VW361_000912"
     CDS             complement(29798..30604)
                     /locus_tag="VW361_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU9743979.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(30949..32469)
                     /locus_tag="VW361_000913"
     CDS             complement(30949..32469)
                     /locus_tag="VW361_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU9743980.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVTV
                     LLGLSYSPALLVQKEKENVIIAGKIGPEPEILANMYKLLIEENTSLTATVKPNFGKTT
                     FLYEALKSGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVSTLEPALRYQAIQSGEIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELETVLNKLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(32462..33190)
                     /locus_tag="VW361_000914"
     CDS             complement(32462..33190)
                     /locus_tag="VW361_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9743981.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(33205..33969)
                     /locus_tag="VW361_000915"
     CDS             complement(33205..33969)
                     /locus_tag="VW361_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU9743982.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAVFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(33973..34416)
                     /locus_tag="VW361_000916"
     CDS             complement(33973..34416)
                     /locus_tag="VW361_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9743983.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(35098..35394)
                     /locus_tag="VW361_000917"
     CDS             complement(35098..35394)
                     /locus_tag="VW361_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9743984.1"
                     /translation="MVEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(35416..36480)
                     /gene="pepA"
                     /locus_tag="VW361_000918"
     CDS             complement(35416..36480)
                     /gene="pepA"
                     /locus_tag="VW361_000918"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU9743985.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
BASE COUNT        11115 a         8055 c         6350 g        11226 t
ORIGIN      
        1 ttctttaaag ataacatttg ttatcaactc atcaggaggt aaatgaaagg caaacaccat
       61 ttcacaaata tcataaaaag aaataaattt gtatacttgt atcaaacaat tattatcaaa
      121 atattctatt ttacctaaat caaaattgat tttataatct ttcataaaaa cctctgagca
      181 aaaatctact caaaaattag atgattaaaa catctaaaaa gcaaaaggac aaaaacatct
      241 gtccctttgt ttactaaatt tcagctaatt tcttcgacat aaataacacc tacaatatta
      301 gcaatttctt ccatcagtcg aagatgttca aatctacctg ataattccag agtaataaat
      361 gacgctattt ttttgtccgg aacatcaaag tattcaattc tgtcagaatt aacatctcca
      421 aacgctgttc ttgaatcggt cattctgata ccattttctg cacaataaac caatacacga
      481 ttataggctt ctgtagattt aaccactata tacaattcaa tcattttaga acgattttgc
      541 agatattttt ttagtggttg gaacatggat atcacacccc aaacagaaat ggctactaaa
      601 agagctccct cataaaaacc tactccaata gctaatccaa ttcctgccga agcccaaatg
      661 cctgctgcag ttgtcagacc tgtaattttc tttttatctg taataagaat cgttccagcg
      721 cctagaaaac ccacacctga tataacttga gctcctaatc gtgtaggatc tcctgtccca
      781 aatttataag atacgtattc attcgtcatc ataatcaaac atgcagctag acaaacaata
      841 ctataagttc ggatgcctgc aggctgggat ttgctccctc tctctaaacc aattatacta
      901 ccaatgacta ctgataaaac aatcctgaca actatttcaa tatttgataa cccaagacta
      961 gtggctgtca tgattatttc cttactttac gccccggtct ttgtgtgaag tataataccg
     1021 ttccagaaat aatcatcaga acaattgtat aaacaaatac cagagcttgt gcattagatg
     1081 ttgctgtttc atcacctgca gatcgaatcg taatacctaa tggttgagct aggggatggt
     1141 aaaggaatac agataagtcg aagtcagtta ataaagagtt aaagtttaaa gcaataacag
     1201 agagaacaac cggtaaaata aatggaatga taaccttcat catagtataa aaaggtgaag
     1261 cacccatact tcttgctgca tcttccatct catcatcaac actaaataaa atagcacgta
     1321 ccattctata agaaaatggg atttttacaa ctatatatgc aataagtaga attaccaaac
     1381 tacctaccaa aatctgattc aagacaagaa attgtggctg attaaaagta aataataaac
     1441 ttactgctaa aagtgtactt ggtagtaacc aaggaagtag agcaccatat tcaaataaga
     1501 aatcaaaacg agatttatgt tttctgacaa cacgagcaaa tacaactgcg agaattgttg
     1561 ctgttgtcgc agcaataata gaataaataa agctgaccaa gaatggagag aatgccgcac
     1621 tattactaaa gaataagcga taattttcta aagtaaagtt tgataatgtt aagttacctg
     1681 tttgaattgc aactggatct gtaaatgagt ataatactat aaaaattagt ggaagcatga
     1741 aaactgtgaa caatccatat gctacaatgt gagcaatgat attccaaggc ttagacgcaa
     1801 ttttttgttt ttttagaggc gctttagtct tagagataga aatataattt ccaccttttt
     1861 ctatcttatt catgatagta agcaaaattg tagttgcaat acctaaaata attgcaagta
     1921 aggcagctaa atcacgagaa ttccccatcc ctgcaaatgt aataatcatt ggatttatag
     1981 tttgaaattc tttaccacca acaatcatgg gtgctgctac tgcagataaa ccactaagaa
     2041 aaaccataat agtaagtgca aatagagttg gaattaaggt tggtaacact acttttcgga
     2101 aaacagtaaa tggttttgct cccatatttc gagcagcctc aatagtgtga tagtcaacgc
     2161 ttcgaattgt atttgttaaa aacaatgtat gattagcagt tcctgaaaat gtcataatga
     2221 ataagactgc accataccca ataaaccagt tagggtctaa agaagggata acattttgta
     2281 aaaattttgt aatcaatcca tatggaccat agacaaattt atatccagtc gctaaaacca
     2341 ctcctccata aattaaagag gtcatataac ctaattttaa aattttagca cctttaatat
     2401 caaagtactc tgtaaataga acacaaagaa tacctacgac attaactgta ataatgagtg
     2461 aaaatgctaa cttaaaactg ttcataatac tctgaagtgc cctctgagat tttagaacac
     2521 gatgtacagc atcaagggaa aattctcctc cttttacaaa tacattcact actagatcaa
     2581 agtttggata aataataaat gttactaaga accagattaa ccctaaacga ataagccaat
     2641 cttttaaatt taatttatga cgcatactgc acctccttaa aattgcagaa cgtctgatgg
     2701 tgtgataaat aattccacac tttctccgac agatctaata gcagcctgac tatcaatact
     2761 tgttacatta agaatctgac tttcagaaac ttttattgta tagtgaattg taactccaga
     2821 aaactcaaca tcaataattg tcccttttag aataaaatct tgttcagttt cacgattgaa
     2881 tcgaactttc tctaatcgaa tgtatccttt tttatcctct aagaaaacgc ttgtattttt
     2941 caataatact tcgtggactg tttcatcggt caaaacatta atatctccaa taaaatcaca
     3001 tacaaattca gtttgagaat tatgataaat ctctactggt gtaccgacct gttcgatgta
     3061 tccattgtta aagactgcaa ttctatcaga taaagtcaag gcttcctctt gatcatgagt
     3121 aacatataaa gtagtaatac ctaactcttt ttgaagtctt ttcaactctt ttctcaaatc
     3181 tacacgtaat tttgcgtcaa ggtttgacaa tggttcatct agacaaagaa ttttaggttc
     3241 aagaaccaga gcacgagcca atgctaccct ttgttgttga cccccagata attctgatac
     3301 attacgctgt aactgttgat cagagatctt aatttttgct gccactgctg atactttagc
     3361 tttaataaca tctggagcta ccttcttaac ttttaaacca aatgcaatat tatcaaaaac
     3421 agtcatagtt ggaaatagcg cataagattg aaatacaata ccaattccac gcttttcagg
     3481 ttccaaatga gtgacatctg ttccattaac ttcaatactt cctgatgatg gatctaaaaa
     3541 acctaccaat gctctcaaag tagttgattt accacatcct gaaggcccaa gaaatgtaaa
     3601 gaattcccct tcatgtatat ctaaattcag attatcaatt gcaacaaaat caccatattt
     3661 aatttgaata ttatcaaatt taatcatctc actaactccc tctattacta aagccaaaag
     3721 cctctcttta tttcttcctt aaatttagaa ataatagaga gacttggaca taaaaaataa
     3781 ctcttatttc ttattttacg tattctaatt cagctttttc tacccattca tccaaatgct
     3841 ttccaacagc ttcccagtca atattttgtg gtttcacttg atcaacaaat tttttcgtat
     3901 cttcaggtaa ctcttttagg gcatctttat ttgcaggaat agatccaaat tttttactat
     3961 attctacttg aatttctgat tgaccaaacc aatcaataaa ttctttagct aacgcttgtt
     4021 ttttactagt gcttaaaacc atagtttgtt cagttacaaa tggtacacca atctcaggag
     4081 tcataacttt gaattcaaca ttttgttctt tttgtccaat taacgctcca gaaccccaga
     4141 tcataccgta ttgaattggg ctttctttat ctaacgcttt aacaactgag ctttcacctt
     4201 tttgaagagt ataggcattt gcaaagtatt cttttgcaac ttcccatcct ttttctgata
     4261 cgcctaaatc tcctttttca tcaaggtaac gaactaagat acttgctaga attgcccgtc
     4321 ctgtaccacc ttgaagacca taaattgaat atttaccttt atacttacta cctaattcag
     4381 tccaatcttt aggcatttct tttacatcag gcgccccaat taaaactaat ggttgaacaa
     4441 tcacaggatt ataataatta tctttatctg ataaagattg atcaatttta tctaaccatt
     4501 taggcttgta ctgtactagt aatttttgat ctctaatttt atttgagtca acagcaccaa
     4561 ttccaaatac catatctgca actgcattat tcttctcagc aataacacgg tctgctaatt
     4621 gagcgccagc gatatcaacc atttttatat taaaaccagc ttcttttgct ttagcagtta
     4681 accaatcacc acgaccattt gagactgagt tcgaatagat aactaattct tgacttttat
     4741 cagctttttc ttcagatgaa gaagcagtcg tagaatttga acctccagag caagcagcaa
     4801 gtgtagtaag agcaactccc gttgcaagta cagtagacca aactttcatt tttttcatga
     4861 taagttctcc ttttttatta ttttatttaa atttttcgtg atatggaaca aattgtctca
     4921 tatcttcaaa tacagtatag tcaatacggt ttacagtaat agttggaatc ttctctaata
     4981 aaatttcagt taattctgct ctgactttag taaactcttc ttcctcctct tcggttagag
     5041 gaatccgaag atacccaatt gaaatatgga attgatatct atcatgatta gggaaacaaa
     5101 cacctgcttt ttctgagaca taagtacgaa tttcttctaa tctctttgca gaagcttcat
     5161 ctgcaggttc aactagtatg ttttgttttc ccatttcagt tatacgcata taaatttctt
     5221 catccaacaa tggaaaaatt tcaagttgtt tagcaaagta atcatgtatt tcctgtaaag
     5281 gtgtatctag aggaagatta ctgctccaaa actccgtttc acgattttca tggcacaaca
     5341 attcaattac agtcatgtga atagaattcc ttggagttaa agtaaactta tcgataaatg
     5401 gtaattctct ataacgtgat tgaataatat caacaacttc catcaaatct tgtttagtat
     5461 aaagatttgc tacaactgta ttcccaggga aatgattaaa ttccccattc tctttgaact
     5521 taatttttgt taagtttttc atataaagac cttctttttt atatttgaca tcggtgtcac
     5581 atgtttacat tatacaatga aaccgtttcc tttgtcaagc gctgtcaaac atttttttta
     5641 atttatcttt cattaaatat gcatttcatt aaaaggttaa gtaatttttc caaaatacag
     5701 cactcatata gacagtatca tcaattatag ccattgggat tttttgattg ctaattccat
     5761 gtatctctac acatgtcttc aatcgatttt gttgtcctcc aatttaattc cttatatgct
     5821 ttgtctgcat ttgcataaca agttgcaacg tctcctgaac gtcttggaac tattttataa
     5881 ggaataggga tcttattaac actttcaaat gtatttacaa gttgtaatac actagtgcct
     5941 tctcccgagc ataggttata gatataaaca tctgtttttt cagatacttt ttctaaagct
     6001 tttatatgtc ctattgctaa atctactaca tgaatctttt atctcatttt tccctttttc
     6061 aaataagtta tctactctat gatcagttat ttccatttcg tttactaaca tgacgcagtc
     6121 acctagcatc atatactcca actttttttc tgaaagttta gcaaatataa aagcaaatat
     6181 tggtaagcga taatatagta tattgaaact agaatagtac acctctactt ctaaaacatt
     6241 gttagaaatc gatttgactg tcctgattga tttgtcctat tattatttca ttttactata
     6301 ctctgttaat tcatatgagt ttaaaccgat ttcatcttta acctcgagta aagcagtttc
     6361 aaatatttgt ttaagagttt ttgattcttt acaattaacc gacaaacttt ctgataaaat
     6421 atgtacaact tctgagactg aataacctat ctcctcttta gaattatata aatctgtagc
     6481 tccaccaata atccaaaaat actgattttg tgaacctaca atatcctcat tttctacgga
     6541 acttccttgt atcgaacaaa ttttatttat ctttaccata atacttcaac ccttttagtg
     6601 tcaaaagtaa accaattcct gtcactgtta agaatagttc cataatctta ttcgaaccag
     6661 tctttggtaa tttttgtttt acatctacta tttctttaga tttattaata tgattttcag
     6721 tttctctgcc atatccaact attttatagt ttacttcttc tgtcttatta tcttgtttat
     6781 tgtcgatctt gtcattcatt tgtctattat ctttacttga gttaaactct ccgttcttct
     6841 ggttactatc aattacatta tttgaattag attgtttttc ctctttgttt ttttcttttt
     6901 cgtttttatc acttaaatta tttgttacaa ttttgtaaag cccattctcc gttacaatat
     6961 tgaaattacc atcgctatca cgtataacag gttctttccc atttgcatta gatttgatga
     7021 atgatatata cttaccggat aaattataaa attggttatt taaaacggtt attttaccct
     7081 ttgaatcctc aataacaatt ccttctttac ccccgaatat actattctct gagactacta
     7141 aattatcact aactcgtaat aattcaatat ttggttgttc tgtttcctta gaattattat
     7201 taattacatt ttttgttaca gtaatatctg atacttttcc taaatattct gcactatctt
     7261 ttgcaactcg tatcgctttt gttttaggat cggcaatatt aaatatattt tcagcgataa
     7321 ccacctgttt atttaaatct aataggtctt tagtgttttt atagctataa gcatttacta
     7381 aagctgctcc gctttctcga taatgtacac tctctccttt aactttctta tcaaagcgat
     7441 ttcctttgat taatacatca gtgaatcctg taaaacgtac acctgcatac atcatgttat
     7501 caaaatgatt atttaaaatt ttaatattag aggggttctg tgtcgacaat gtttgatagt
     7561 gtgtgccaat tgctgttact aattccccag atttatcact tttgccaaaa taggaatttt
     7621 gaatagtcac attttcagat tttttcccat catcattcaa ggcataagga aaaccttttc
     7681 tagttaatgg ttcaatctga atgctctcct tacttatgat ttgcccatcc ttcatcgttt
     7741 tgggtaaggc ttgcccaaga aaacgagaat tatcaactaa tacatttttc gaacctgcaa
     7801 tttgaatagc atgcccttga taactatcct tgaatgttac attttttata gttacgttat
     7861 ttgaattccc aatagcaaat gcacctgaag aatttataag tggtagattt tttgctttag
     7921 ttccttcttc attcaaagca ccgttcatat caatcgtacc accagaataa ctaatatctt
     7981 ctgttgggcc ccattctact tgcgcaccat catccgtaaa taaacctgtc ataaaaacaa
     8041 tggaagggtg attcttaata tttataccat ttagaattgt agctttctca ttcaattcta
     8101 agtgtgtatg actttttaaa aaaacaattt cttttactaa ataagttcct tcaggaaaat
     8161 atacatttcc tccacctagc ccttgagctg cagcatctat tgcatcttga attgcttgtc
     8221 gatcatcatg aatcccatca cctaccgcac cataatcttt tacacttaaa gcagtatctt
     8281 caaattcttt tttgataatt ctgtcactta taacatcttc cttataactc ttattttcat
     8341 tagtagatgt tactgtagat tcaactgttc tgttgtctaa ttgtgaattg gaacgaatag
     8401 taccattaga gctgatacta ttaacactta acgaattatc taaaccatta gtggttgaat
     8461 tagaggcaat catttcagca gaacgattct gattaacagt tggtgaatta tctaaatcat
     8521 tagtaattgc attagaagac tcttttgtag ccatcggtga agaactagta acaacttcat
     8581 ccgataaaat accttggctt cccaaaattg aaattgccaa tagtaccgag caagtcccca
     8641 cctttaattt acgaatactg aatacctcat taggaacaaa atatttcatc agaacctcca
     8701 atttttttac tatttttaac aattgattat tacttttctt aaaatagata gaatgacacc
     8761 gctgtcatta tctttatcat atattttcca aattgaattg tcaaggaata acacaagaaa
     8821 atattaaaat ttatactctt cggaaatctc ttcaaactag gtcagtgccg ccttgcccta
     8881 agtctaggtt actgacttgg tcagttctat agtagactga aactataata gtacacctct
     8941 acttctaaaa cattgttaga aatcgattta actgtcccga tcaatttgtc ctattcttat
     9001 ttcattttac tatatctaca acctcaaagc agggttttga gctatctatg gccaacttcc
     9061 tagtttgctc tttagccttc cattcaaaag tgatgctatc tttcttagct tgaatataaa
     9121 atatcccatt tactatattt aaatttattg atatgttgta aattataaat gaaagaacaa
     9181 ataccttgtc atacaagcat tcgccaggga tatttacctg aatatcgctc atatggcgga
     9241 ttgaaactaa aacactacaa tatatttctt aaatagacct tctataaaag ctagatttaa
     9301 cctcgataaa aatagatgca gtgcttctaa aatactggaa tagggcatat aggtaatcgt
     9361 agacaagtgt tttatagatt gtctcgcagg agatctaatg atgtatagca agcatcacta
     9421 aacatatggg atattcgtat tattataata tcaacatgct ataaattcta tcatgcaaaa
     9481 gaatgactag aacatgaaag acaggcacaa aactttgaac aatattctga aaacaaaaaa
     9541 agacgcgagt ttccacaatc tcactcatgg aaactcacgt ctttcaaaaa atagggtgaa
     9601 ttgaaaacta gaacaagaca ctagattttc taaatgatgt ctagtaagga ttctaaatgc
     9661 tacaccaaat tgctcacatc ttatttcaaa ccacgggact cccacaagaa aggaaaatcc
     9721 tataaaaatt ctctctctga ggagaaagag gcctcaacta caggtgtaaa ctattatcaa
     9781 ttgaaaacaa cagtttttac actcaattag actttttagg gacaggatca ctttcgcttg
     9841 actgtagttt gtcatttttt tgataaagtt agcacttttt cagaaactgt tttgaaagtc
     9901 tcaatgatat agtctacttc ttcatcgctt aatttagtat gaagagggag ggtaatttca
     9961 ttctcaaaga aggcataggc cttaggatag ttcgtcatat caaatccaag attcttatag
    10021 gctgtcaaga gaggaagcgg tttgtagtga acattacttg caattcctgc tttagccaat
    10081 tcttggatga tgaggttgcg ttcttctagg cttgctcctt ctacacgggt gatgtagagg
    10141 tggcgtgaag attcgacagt ttcagtcttg tgtgccaaag gatggatgcg agaacctgca
    10201 aaaccactat catagcggtc cacaatgtcc ttacgacgtt gcaacaaact tggatagcgg
    10261 tccaattgta ccaaaccaag tgaagccatg atatcggtca tgttgcactt ataggctggt
    10321 gtaacgatat cgtattccca tgaccccagt tgcatcttgg caagagcatc cttagtttgc
    10381 ccgtgaaggg aaaggatttg gaattccttg tacatctctt cgtcatcaat cactggattg
    10441 gctttccaag tcgcacttcc accttctgcc gttgtaaagt tcttaacggc atggaatgag
    10501 aaggaagtaa aatcagcgat agaaccagaa ggttgtcctt tataagtaga tcccaaagcg
    10561 tgggcactat cagagacaat gacaatacgg ttaaaggcct tttgccactt gcttgaagcg
    10621 gtaaagaagt cacgtttttt ctccacgact tggaacaaac ggtcataatc gcaaacaatc
    10681 cctgcgagct ctactgggat aatcacctta gttttctcag tgatagcttg ctcaagcagg
    10741 tcatagtcca tctcaaacgt atctgcttgg atatccacca tgacaggggt tgctcccacg
    10801 tgcgtaatga cactacatga agccgtatag gtcatggctg gaacgatgac ttcatcacca
    10861 ggtcccactt ccaaaacgcg taaaatcaac tccagagcgg ctgtcgcaga gttgagacaa
    10921 acagtcttag gtgtctgtgt gtaaagagac aagcggcgct ccagttcttt tgttttagga
    10981 cctgttgtga tccaaccaga acgcagggta tccgctactt cagcaatttc tgcttctgtg
    11041 atatcaggcg gtgaaaatgg aatattgtaa tttggcattg atttgctcct tttatctgta
    11101 ctcattttct tatgactact ttattttagt acctcaaaca cggtttgaaa catgattttg
    11161 atgtccccaa agaaactaaa ctctcggaga taggcgaggt tatagcgcat cttttcagga
    11221 agaacatgct ccacataggc ctgatcaact gacagacctt tctccgtcat ttgactgatg
    11281 atggtgtcct catccttgta gttgatgctg gctggagagg taattcctgc ttgcaagagc
    11341 aaggttgcca tcatttcagg gctatactgc tctgtataac gtggcacttc aggtcgtgta
    11401 ccgacaaagg acatctcacc tttaaggaca ttgaccaact gaggcagttc gtccaaacgg
    11461 acacgtcgga tgaaatttcc aaccttggta atacggctat cgttagcaga agtcaccaga
    11521 cttccttttt tatccgcatc cgtcaccatg gtacggaact tccaaatctt gaaccgacgg
    11581 ttgtactggg tcacacgctc ttgcttgtaa atcactggcc ccttgctatc caacttgatc
    11641 caaatgctca agatgagaaa gatgggagaa gttagaacca gtaagaccaa ggccaaaacc
    11701 cagtccaagc aacgcttgaa aatcagcgaa cccttccttt tagagacaag ctggtagtaa
    11761 gactcaacct cgcttgattt catttccaca ggcaagtctt cccatttcag catgctgttc
    11821 tcctttgttt ttattatact atttgtcaac atttttcatt ataccacaaa atggaaaagg
    11881 cggtgaaaga aatctgtaat ttgaaggatt tccttctagt actcaatgaa aatcaaagta
    11941 cagctttgag attgcagata aagctgacat ggtttaaaga gattttcaaa gagtatcggc
    12001 catggcccct gcctgcaaac tatacatctt gtgataggtt cctcccagag tcaagagttc
    12061 ctcatgggtt ccactctcga taatgcgtcc cttatccaag acatagatgc agttggcgtc
    12121 ttgaatagta gaaaggcggt gagcgatagc aatagttgtt cggccctgtc tcatcttcgc
    12181 cagagaagct tgaaccaaac tttctgtttc agagtcaata ttggctgtcg cttcatccaa
    12241 aatcaggatt ttaggctggc tggcgactgt tctagcaaag gcaagaagct ggcgctgccc
    12301 agtagagaag ctcgaaccac gctcggaaac aggggagtcg tacccctgag gaagttcttg
    12361 aataaaggaa tctgcatcca caaaggctgc cgcagcctga acctgctcat cactgatttc
    12421 ttggtacatg gcgatattgg acttaatagt tccatgatag aggaagggtt cctgtaaaac
    12481 caaaccgatg ttttttctca gctcttcttg actgaaatcc ctgatatcca catcatccaa
    12541 gagaactctc cctgactgga attcataaaa gcgcatgagg acattgataa tagacgattt
    12601 ccctgaacct gtatgaccta caaaggcaat ggtttcaccc ttattaacag agaaagaaat
    12661 gtcatccaga atcggatgtt taccgtcata cgagaaacac acatgttcaa aacggatatt
    12721 gccttctttg actttggctt gcccattttc ttgaaggggc tcataggtcc tctcatcgat
    12781 taaggcaaag acacggcctg cagaaaccat agacgtttgc agtgttgaaa agttttgcgt
    12841 cacctcaatc aaagggtcaa agaggcggtt gatgtactgg ataaaagcat acatggtccc
    12901 ggccgttatc ccgatagaaa gaccacgata gccaaaatag gtcatcaaga cagcataacc
    12961 tagaagtttc aacaaactca tggcaggtct caaaaagagg gcatccaagg ctacagaacg
    13021 gttggcatag gccaagtgct cttggttgat ttcatcaaat tctgcctgca ggcgcttctc
    13081 ttgattaaag gcctgaataa tcctgattcc ctcgatattc tctgccagct tactattgat
    13141 atctgacaag agacttctgg ttttctcgat gattttcact gacttttttc gatagagatt
    13201 gaccaaaagg aaaatcaaag gaagaaagag caagactaat gctgtcaaac gaaaatccag
    13261 caccaacatg gtataaaggg ttgtcagaaa gataaaaact gctgagataa agctggataa
    13321 aatcccagaa aacatatcac taatcgtctc ggtatcgttg gtcaaacgag aaacgataga
    13381 acctgctggc gtcttgtcaa agtaagacat gcccagtttc tccatattgg caaaggcatc
    13441 ccgacgaata tccctaacaa tactgtaaga cacgcgcgca aagagaagat tgccgacata
    13501 ctgaactaca gtttgtagga tgtagagacc atagtagacc agcaaaacgg tcacggctag
    13561 ttggttaaga ttgctgagat actggtcgat aaagtgggaa gccacaaggg gaatgacact
    13621 tttaatgacc gtcgtcgcta ggagaaaact gagtgccaaa aaggtaagga gtccataagg
    13681 cttgagatag gacatcaagc gcttcaatac agtccattgt tcttgtttat tctgcatctt
    13741 cttctccctt catttccagc tgctgagact ggtaggtttg ggcataccag ccatccaaag
    13801 ctagcaagtc ttcgtgcctg cctcgttcga taatttgacc attttgcagg actaaaatca
    13861 aatctgcatg gacaactgca ctcaggcgat gggcagtgat aatggttgtc ttgtcctttc
    13921 gcgtctcctt gaggttgtcg ataatcgcat actctgtctt ggcatctacg gcggataagg
    13981 aatcatccaa aatcaagata tcagggtcta aaatcatagc ccgactcata gccaaccgtt
    14041 gcttttgacc accagaaaga ctgactcctt tttcaccaat cagcgtatca aatccttgag
    14101 gcatgtctac aatatcttgg taaactcggg ctagcttagt agcttcctcg accgctgaaa
    14161 ggggcaagtt aggattgcca aagcggatat tgtctaggat tgaagtcgca aagagaaact
    14221 ggtcctgagg aacatagccc atgagactgc gaaggtctgt cagacgatag tcccgaatat
    14281 cgtgaccgtt tagataaata gtacccttat ccacatcgta ttcacgcaag aggagcttga
    14341 ttaaggacgt tttcccagag cctgtctgcc caaccaagcc cagtgtttgc ccttttgcca
    14401 aactaaagtg aatatccgtc agtgtttcct cattttcaaa agcaaagctg tcaatggcat
    14461 actccaaacg cccattttca ataccatcca gaggaaactc agggtcttgt acaggagatt
    14521 cctgagacaa aagattttca atccgctggt aagaaacctt ccctcgctga gtagtattaa
    14581 agaggaaacc gatggccaga agaggccaga ccagcatatc caaatagctg ataaaggtga
    14641 ctagattccc aactgtaatc tgcccttcct gaaccatcaa ggagccaacc aaaagcgtta
    14701 aaacatagga cgaaccaaca aacaagagaa ccatagggtc aaagagacta tcatatttca
    14761 tggtttgcag gttcttttgg aaggttaatt cattgactgc ctgaaaagac ttcaactcgt
    14821 ctgcctgata accgaaagac ttggtcactt tgatacctga tacggactcc tgtaccttgt
    14881 tattgagttc agaaaaagca gcttgggatt cgccaaaggc cttatgagtc tttctcccta
    14941 ggcgactagt cgtataggcc atgaaaggta gggggagaat ggcaacaaga gtcatctgcc
    15001 atgagatgct aaagagcatg gtcaacaaag tcaccagagc cgtgatagag gcatccaccg
    15061 cagacatgac accgccacct gctaaacgag tcaaggcatt gatatcattg gttgcgtgtg
    15121 ccatcagatc acccgtccga taggtttgat aaaaggctga cgacattttt gtgaaatgct
    15181 taaacaagcg agaccgcatg atctgtccca agcaataaga ggtcccaagg atatacatac
    15241 gccacacata gcgcaaatag tacataccaa aggctgcaag tagcaagtaa aataggctaa
    15301 gaaggaggtc ctgctgagtt aattgccccg atgtgatggc atcaatgact cgccccataa
    15361 ccataggagg aatgagattg aggacggaaa ccaagaccag ggccacaatc ccgactagat
    15421 aacggcgttt ttctaacttg aaaaaccacc agagtttttg aataatggac ataaaatccc
    15481 tttctgattg caaatggaaa cctgaggcca atactcaatg aaaatcaaag agcaaactag
    15541 gaaactagcc gcaggctgct caaagcactg ctttgaggtt gtagatagaa ctgacgaagt
    15601 cagtaaccta catacggcaa ggcgacgttg acgcggtttg aagagatttt cgaagagtac
    15661 aagaccccag gtttttctta ttcataagtt acgactgtaa cagcaccctt gtcatattca
    15721 gcaataaaga tattggctac attgtcatgc ccttgtttac tgaggttatc aagcaaccac
    15781 tcttcgctac gaccaatcga ttccaagaca tctacttgaa tcacaccgtc agtcacaact
    15841 ggatacttag gattttcatc tcccatttgc acaacgataa gttgcccatt ttgctcttgc
    15901 acagctcgtt tgacttgctt catctggaaa atcccttggc tacgaagttt gagggctaca
    15961 tccgatgcag acaaaccaac tgaacgacag gcttctgggt caatattccc atttttgata
    16021 aggagagttg gcttaccatc aatcaaacgt ttcacaaagt gaacattgtt gttgagccat
    16081 ttgagagtca agaccagttt gattaaaatt tcgatataat taagtgtcat ttgttcacat
    16141 ccaccagttc aattgcgtct gtcttataca attcgacttt ctctaacagg tacttgtctg
    16201 gctcacttcc gtttagggca cgataatagc gatctcccac cttgataagt gcgccatctg
    16261 tgtttgtgga agtattaaca tagacttctg acttgtctac tcccaaatct ttggaaacaa
    16321 cctcgatgaa atgaagtgaa gtttgaaatt tattgttaga aacttgattg ttttgataag
    16381 tcgtgatgct gaccaaaagc agagctaaat aaggccagag ctgaaatcat gaccaactca
    16441 cgaaattcgg ttcccttttt atcatggtat gccttgaaag caaaaaaaac tgtcacagct
    16501 aatagaacaa tcccaaagcc aaccatgata ccattttgct gaccgatttg gctgagtaca
    16561 tagtcataag agtagaattt catatatttt cactcccttt cataaaatca ttcttaatta
    16621 taaacgaaag agagtaattt ttcaaaccat acgttgggga aatagatctt tttttggtat
    16681 aataaaatct ataatctgaa tgaaaaaggt aactttatga aacttatctc atggaatatt
    16741 gattccctaa acgctgccct aactagtgac tcagctcgtg ccaaattgtc ccaagaagtc
    16801 ctacaaacct tggtcgctga aaatgctgat atcattgcta tccaagaaac caagctttct
    16861 gccaaaggac ctacaaagaa acacttagaa attttagaag aactcttccc aggctacgaa
    16921 aacacgtggc gttcttccca agagcctgcc cgtaaaggct atgctggaac catgttcctt
    16981 tataaaaaag aacttacacc tactatcagc ttcccagaaa tcggtgcccc ttctaccatg
    17041 gacttggaag gccgtatcat cactctagaa tttgatgcat ttttcgtaac ccaagtttac
    17101 actccaaacg ctggtgacgg tctcaaacgc ttggaagaac gccaagtctg ggatgttaaa
    17161 tatgctgagt atttggctga actagacaaa gaaaaaccag tccttgcgac cggtgactac
    17221 aacgtagccc acaatgaaat cgaccttgca aatcctgcta gcaaccgccg ttcacctgga
    17281 tttactgacg aggaacgtgc tggatttacc aaccttttgg caactggatt tacagacacc
    17341 ttccgccatg ttcatggcga tgttcctgaa cgctacactt ggtgggcaca acgcagcaaa
    17401 acttctaaaa tcaacaatac aggctggaga atcgactact ggctcacaag taaccgtatc
    17461 gctgacaagg tcactaaatc tgatatgatt gactcaggtg ctcgccaaga ccatacaccg
    17521 attgtcttgg aaattgactt gtaagaattt tctatatgga ctacaatgcg gtcattcccg
    17581 agttgcttgt atcgaatatc gaacagtccc ggtccttcta ctgtggttta ctgggtttta
    17641 ggattgaata ccaacgtcca gaagaaaact ttctctttct ttctcttgaa gagtgtcaac
    17701 taatgttaga ggagggaaca aaggatcaac tagctgaact gacctatcca tttggtcgtg
    17761 gagtcaatct ctcctttggc ataaaggatg tttcaaaact ctattaaaga gtgatgaagg
    17821 caaactatcc tatttatcgc ctcttgacca aaagaaagtt tcgtgtcagt gatccctata
    17881 tctatcctca taaatttgca gttttggatc caaatggcta ttttttaaga tttagcgagt
    17941 agaataataa aaattgggaa aagtctttaa agttagaaaa aggcatattg tcaggtgttt
    18001 aaaaacttga tagtatgcct tttatgatgg aaaaatcttc taatactctt cgaaaatctc
    18061 ttcaagccac gtcaacgtcg ccttaccgta ggtatatgat actgactctg tcaattctat
    18121 ccacaacctc aaaacagtgt tttgaggttg tggatagctt cctagtttgc tctttgattt
    18181 tcatttagta taaatattag cttacaatgg agtttttgtt caccctctct tctgtttgtt
    18241 cgttttttaa accaaaacac taacaaaata gttgatttat aaagttattt agtgtaaaat
    18301 aaaaacattg gctcaagcct atttaaaatt gaatatcgtt ttacttgttt atgtcgtgaa
    18361 ttggcacgac gtttctacaa ggtgccggaa cacctaacaa taagtaagtc agcagtgaga
    18421 tatggccgtt tttgccatgc ctatttgggg gacttactta gagattaagt aggtcttttt
    18481 tgaatatttt taatatttcc cttaattagt gcggacggga ggtgaaatta tcctgtgaat
    18541 aatttcagga atccagggaa tttcatccct aatttttgag ccaaaagtct caaaaatccc
    18601 gtcatagaca ataacaagat tattgtctat gataccacta caacgggaaa tatttgataa
    18661 gactcgcttc gctcgtaata gttttatcaa atatatagta ttagcaaaag ggatcactat
    18721 agaaatattt aaacaacaag taaattaact tttagacttt aggaggtctt atgaaattat
    18781 tagaagagcg catcctcaag gatgggcata tcttgggtga taacatcctc aaggtagatt
    18841 cctttttaac ccaccaagtt gactttagct tgatgcgaga gattggtaag gtttttgcgg
    18901 aaaaatttgc tgctactggc attaccaagg tcgtaaccat tgaagcgtcg ggtattgccc
    18961 cagccgtttt tacagctgaa gccttaaacg ttcccatgat tttcgccaaa aaagctaaga
    19021 acatcaccat gaacgaaggc atcttaactg ctcaagtcta ctcctttacc aagcaggtga
    19081 ccagcactgt ttctatcgct ggaaaattcc tctcaccaga ggacaaggtt ttgattatcg
    19141 acgatttcct tgctaatggc caagctgcta aaggcttgat tcaaatcatc gaacaggccg
    19201 gtgccacagt ccaagctatc ggtatcgtga ttgagaaatc cttccaagat ggtcgtgatt
    19261 tgcttgaaaa agcaggctac cctgtcctat cacttgctcg cttggatcgt tttgaaaatg
    19321 gtcaggtcgt atttaaggag gcagatctct aatgcaaact caagaaaaac actcgcaagc
    19381 agccgttctg ggcttgcagc acttactagc catgtactca ggatctatcc tggttcccat
    19441 catgattgcg acagcccttg gctattcagc tgagcagttg acctacctga tttctacaga
    19501 tatcttcatg tgtggggtgg caaccttcct ccaactccaa ctcaacaaat actttgggat
    19561 tggactccca gtcgttcttg gagttgcatt ccagtcggtc gctcccttga ttatgattgg
    19621 gcaaagccat ggtagtggcg ctatgtttgg tgcccttatc gcatctggga tttacgtggt
    19681 tcttgtttca ggcatcttct caaaaatagc caatctcttc ccatctatcg taacaggatc
    19741 tgttattacc acgattggtt taaccttgat ccctgtcgct attggaaata tgggaaataa
    19801 cgttccagag ccaactggtc aaagtctctt gcttgcagct attactgttc tgattatcct
    19861 cttgatcaac atctttacca aaggatttat caagtctatc tctattttga ttggtctggt
    19921 tgttggaact gccattgctg ctactatggg cttggtggac ttctctcctg ttgcggtagc
    19981 tccacttgtc catgtcccaa ttccactcta ctttgggatg ccaacctttg aaatctcatc
    20041 tattgtcatg atgtgtatta tcgcaacggt gtctatggtt gagtcaactg gtgtttatct
    20101 agccttgtct gatatcacaa aagatccaat cgacagcacg cgccttcgca acggttaccg
    20161 cgcagaaggt ttggccgtac ttctcggagg aatctttaac accttccctt acaccggatt
    20221 ttcacaaaac gttggtttgg ttaaattgtc aggcatcaaa aaacgcctgc caatctacta
    20281 cgcagctggt ttcctggttc tccttggact gcttcctaag tttggcgccc ttgcccaaat
    20341 cattccaagc tccgtcctcg gtggtgccat gctggtaatg tttggttttg tatcaattca
    20401 agggatgcaa atcctcgccc gtgttgactt tgctaacaat gaacacaact tccttatcgc
    20461 agctgtttca atcgctgcag gtgtcggtct caacaacagt aatctctttg tcagcatgcc
    20521 gacagccttc caaatgttct tctcaaacgg aatcgtcgta gccagcctac tcgctattgt
    20581 cctcaatgcc gtattaaatc ataaaaagaa ataagaaaaa gaggtgcgag cctctttttt
    20641 gttgacaaaa taaaaacatc tacctattca tatatgctag tgtcatagtc ctgaaaatca
    20701 tctgcatcaa gaacaatttc acaactctta tacttttctc ttacaagtcg ttcggcttca
    20761 tctggatttt cagcctctat acttactaaa cgtgataaag tttctgtaat ttctactgta
    20821 tactttttca gttttagatt gctttccaat aattcaccta ttaacaataa tctatgatag
    20881 gagctatgta gccactctgg caatttatct cctacttccc acccatattt ttccttcatc
    20941 aaagctagtt gtttttcgtc accaaatttc atattttcag ataaccatct cacacaatcg
    21001 ggatctgata aggtacagac gattaaactt aggttatcgt aacggctttc agtttcataa
    21061 tcaggccaga tgacttttaa gaaatcatac acctcttctg atgcaacaag ttgtttcgtt
    21121 ttcataattt ccgatacttt cctctacctt taaattctat tatttctttg tctcttaata
    21181 tttgaagctg ttgcctaatc ttttctttga tatgattgtt cttaacaaag atatttttta
    21241 ggtcactttc aaaacgatac atatcttcaa gggtaaattc tgaaccctct atcttatcta
    21301 tacaatttag aatttctatt gtccaacctc ttgatgacag agagctcttc cttaaaaata
    21361 aaccttgctt aaattctttt gtaacttttt ctggatctct aacttgtcca tcttgcacaa
    21421 gaaatatcct tcctttagaa ggtacttgtg ataaatcaat gtcacaacca atccaacctg
    21481 ctcgtctagc agttggtgca agtggttttc tttgaataat cgatttcggt gtaacaaatt
    21541 gcttcggaag gacaagaaag ttatttacct caaaattttt tgtgtaagtt aaaaaaaaga
    21601 aattaggatt attatctgcc tgcacacgct tcatcatcgt tgcataagca ccatcattga
    21661 ttgttgatga aaaatttcct tttttgctct ttagttcaaa ctcctcacta caatgattac
    21721 agtaaaaatc tgctacaggc cgattatttt caaaatgatt taagggattg ttcccacaat
    21781 tagggcaata agactgacga taaacccaat cctccgttaa gatacgtgcc ttttggctat
    21841 tacttttata ggtttctact aattctaaat taaaatgtaa ttccatttaa aaattcctca
    21901 ctaatatgag aactcactcg atataagcaa ttaaaatcta ctataactag tataccacat
    21961 atatgtacct attacatttg tatttcatca ctctctttta tatttccttc taacatatct
    22021 cataaattaa aaatgagtga gataaattta tcccactcac ctttctttat atacttaccc
    22081 gtctttcctc agacctttgg cctgtgacaa acatggtaaa ggttgcttta cagacatttc
    22141 tgccctcttg attggtgata tccacatcca tcacacaggt tgtacgacct tgatggacac
    22201 attctccttt aatggtcaat acatcgtcga gttttcctgc cttaaggtag ttgatagagg
    22261 attggagtgt caccccatca agtcccagcg agataaccac caaaccactg atttggtcac
    22321 atagcgtgaa tagatagcca ccatgggcat tgccatagta gttgagcgac gagttcacta
    22381 ctttggtcgt caccacaacg tgaccatctc tcattttttc aatttcgtaa ttttcaaagg
    22441 cagatatagc gtcaaaatga aagtctttca tcgtttcctc ccgatatttc aaacgacact
    22501 atgatactac tttttatagg actgtgcaag gagaaagctc ctagtctagt aaaattccga
    22561 cctgttccac aaagcgcata aaggctgtct gcccttgttc tgtctgcttg tagactcctg
    22621 catcctcaag tacacgcaca aagatagcac ccacagagtc cttgacgatt gcaagggttt
    22681 tttctttatc cgttaggtct ggatgttggg attttagttg gtctgcccac tcctgatgat
    22741 aatcggcaac tgtaacagct tctcctacaa gatagctagc gacttgctcc acttcttctt
    22801 tcagacgtgg tggcaagatt gccaagccca tgacctcaat caagccgata ttttccttct
    22861 tgatatgttg gacatccttg tggggatgat agatgccatc aggatgctct gctgaagtct
    22921 gattgtctcg caagaccaag tccaactcaa actgtccatc acgcttacgc gctattggtg
    22981 tgatggtgtg atgcggtgtc ccgtctgtct ctgccaaaat ctgcacacta gaatctgaat
    23041 actgacgcca ttcctggaaa atcttatcag ctaagttaat caaatcctct ttggaatccg
    23101 aagtcaagcg taggacagac attggccact tgataattcc agccttgacc tgctcaaaac
    23161 cagcaaatcg gaaggtcttt tgcaagggag ccaattccat aggaaatacg tgacggcctc
    23221 cctgataatg atcatgagtt agaatagagc cccccacaat cggcaggtcg gcattagatc
    23281 cagcaaaata tcctggaaac tgctctacga tagccaacag acgttcaaaa ctctgacgac
    23341 taatggccat gggacgatgc tggccatcta aaaagataca atgctcatta aagtaagcat
    23401 agggcgaata ctggaaaccc cattcctgac caaccatttc aaaacggata atccggtggt
    23461 tggtgcgagc tgggtggttg acccgaccat ggtaaccctc attctctaaa caaagttgac
    23521 actgaggata attactagct tgcaccaact tggctgccgc aatctctttc ggatcctttt
    23581 caggcttaga gagattgatg gtaatttcaa gttctccata atcagatgga acacgataag
    23641 cgatattttt agcaatggcc ttgagtttga tgtagtcatt tttctgactg agttgataaa
    23701 aatcctctat cgcttgctca ggagagtgga cataggcttc ccagaagtca cgattgacct
    23761 gactcggaca aggagtcacc aagtccatca attcagtacc aaggatttca cgcgcagtct
    23821 gactatcctc aatcgtctct aatcgaacgg cttcctcaac tagctggtcc ttgaggtcaa
    23881 tcaatttatc cagattggtc tcaacttcca aaacaccttc tcccactcgt gccaaaacac
    23941 gattggtcag gtagattcga tccatttcct caaatgaact ttcagaaatg acatgtgtta
    24001 caaatttatc tactaaggtc actatagagc ctccttttga ctagtcaaag acgcgagtgc
    24061 cacctgcaac ttcagcgata tagaagcttg gagcgtatcc aactacttcc ttgtagtgtt
    24121 tgcctacagc ttccttaaag gcctcaacag tatctttttg aaccaaggca atggcacagc
    24181 caccaaaacc agcccctgtc atacgagcac cgagaactcc ttcttgtgcc caagctgtgt
    24241 gaacaagagt atccaattcc aaaccagtta cttcataatc acgctccaga gaaacgtgtg
    24301 acgcattcat caaacgacca aatgtttcca aatcacctgc ttgaagggct gcttgagctt
    24361 taagggtacg ttggttttca agcacagcat ggcgagcacg tttcaaacga ttttcatctt
    24421 taatcagata gctatattgg tcaacggccc actcgtccaa ttcacccagg gtctgaatat
    24481 ccaaggcaac ttgcaattct tccactgctt tttcacactc agcacgacgt tcattgtatt
    24541 tagagtccgc caattcacgg cgtttgttgg tgttcatgat aacaacgaca ttgtccttca
    24601 aatcaagtgg caccaagtcg tattctaaag tattggtatc taagtaaata gcacgttggt
    24661 cagcccccat accaatagca aattggtcca taatgccaga atttactccg ataaagttat
    24721 tttctgtttg ttttccgatt ttaaccaaat cgagacgctc tagttttaaa tcaaagagat
    24781 gctctgccac aactcctgtc aagagctcca aggatgctga agaagacaaa ccagcaccat
    24841 ttgggatatt cccataaaca taaaaatcaa aacctttgtc aatcacgtgc ccagcttctt
    24901 gcaagaaatg aaggacacct tttggataat tggtccagtt gtgctctttt tcaaacttga
    24961 ggtcagcgag aggcacttcg ataatgccct tgtcctcaaa gttagctgag tagaaacgca
    25021 agacttggtc gtcacgctta cgagctgcac cgtaagttcc caaggaaata gcagcaggaa
    25081 aaacgtgccc accgttgtag tctgtatgtt caccaatcaa attaatgcgg cctggtgaaa
    25141 agaaggtttg gtctgcttct tgaccaaaaa cagcaagaaa gtctttgcga agggcttcag
    25201 tagtaagatg ttgtgccata tgaattctcc tttgactgtc cgttaagcca tcttaacgtg
    25261 taatcgtttt ctttctattg tatccaagga attttccaag gtcaatcctt tttactaaaa
    25321 ttttagtaaa atatcagtaa aaagaagaaa aacatgatat actaacctaa tcaaggagga
    25381 tttatggcta ccttaaaaga cattgcacag ctagcctctg tctctatcgc gaccgtatcc
    25441 cgcgtcctca atcgcgacca gagcctatct gttacagaag aaaccagaca ccgtatttta
    25501 accgttgctg aagagctggg ctacaccaag cacctcaaga caggcgagtc ccacaaaccc
    25561 aagcaaaaga ttgccattat ccaatgggtc agcgaacaag gggagctgga cgacctctac
    25621 tactaccaga ttcgcctagg aatagaaaaa agagcccaag agttggacta tgatatcttg
    25681 cgctatttta atgaccaccc ttttacccta agcgaggaag tgattgggat tctctgcatc
    25741 ggaaagttta gtcgagctca gatttctgcc tttgaagaat accaaaagcc tcttgtattt
    25801 ctagacagcg atacactttc cctgggacat acctgtatta tcacggattt ttacactgct
    25861 atgaaacagg ttgtcgatta tttcctcagt caaggaatgg accgtatcgg gattctaaca
    25921 ggccttgaag aaacaacaga ccaagaagaa atcattcagg acaagcgtct agaaaacttc
    25981 aaaaactaca gtcaagcgag gggaatctat catgatgaac tggtctttca aggaagattt
    26041 actgcccagt ctggctatga cttaatgaag gaggccattc agagcttggg agaccaactt
    26101 ccgccagcat ttttcgcagc cagcgatagt ttagctatcg gtgccctccg tgccctccaa
    26161 gaagctggaa tcagcctgcc agatcgcgtc agcctcattt cctttaacga cactagtctg
    26221 accaaacagg tctatcctcc cctctctagt attacagttt atactgaaga aatgggccga
    26281 gcaggtatgg atattcttaa caaggaagtc ctccacggtc ggaaaatccc tagcctgacc
    26341 atgctgggaa ccagactgac attaagagaa agtaccctaa atcaagaata ggataacata
    26401 aaaaacgaat agagttctaa aactcctatt cgttttttat tcgattacaa tcatagactt
    26461 aatggtctta cgttcatcca tatctttgta ggcttggtcg atatcttcca gtttataact
    26521 tgaagtaaag acgcgacctg gattgatatc accatcaagg acggctttta gtaaaaattg
    26581 cttatcgtat gttgtagcag aagctgcccc acctgctaca gagatatttt gcataaatgt
    26641 cgaaccaaga gcacgattat tatagtgtgg gactcctaca aagcccatac gccctccatt
    26701 atgaagaaca cctagcgcct gttctatagc agcctccgta ccaacacatt caagtgctgc
    26761 gtctgctcct ccgccgagga tttcacgcac cttggtaatt ccttcttgac cacgttctgc
    26821 aacaacagct gtcgcacctg actccatagc catcttttga cggtcttcat gacggctcat
    26881 aaggataatt tgtgatgctc cacgcatctt agccgcgatg acagcacatt gaccaacagc
    26941 cccatcaccg ataacaacaa ccttgtcccc tttttgaaca tttgcaacac gcgccgcatg
    27001 atagcctgtc ggcatgacat ctgcaagagt caaaagggac ttgagcatcc cttctgtata
    27061 gtcagaaggt tgaccaggga ttttaaccag cgcccagttt gcatagtgga agcgaatata
    27121 ttctgcctga aaatcacccc ccaaattatt gccaatatga ttgtcgcaag aaccgtcaaa
    27181 tccagcaaga caggcatcac actcaccaca tccatgtgta aaagggacaa tcacaaaatc
    27241 acctggtttc accgtcgtaa tggcttcccc agcttcttca acaatcccaa tcgcttcgtg
    27301 tccactattt ttgtgtccaa ctttcgtttc tggattacgg tacctccata aatctgaacc
    27361 acaaacgcac gcacgaacca cacgaataat cacatcatcc gcttctatta tttgcggacg
    27421 ttcaatgcta gcaagtccaa cctgacctgc ctttgtatat actgctgatt tcatttaaaa
    27481 ttttccttcc ttataaagtt taattttgag atttaaacga tttaaagctg tctgtatctg
    27541 agacaagcgc tcctctaatt tttgcttttc ctcttctaaa ataccaagcc tctcctctct
    27601 cgtttcatct cccttttggt agagcgacat atagtcaact aaactatcta cagagacacc
    27661 cgccgaacga aaacacttaa taaattccag cgcttcgata tcctgatctt gaaaatcacg
    27721 aatcccagta gcagtacgag taatcggtgg cacaagacca acccgttcat aataccgaat
    27781 cgtatccgct gaaatttcca acaaatcact ggcagattta atattcacac gctaacctcc
    27841 tctcatttca ttcactgagt tcacgctatt ctaactcact tatcttatta tataactttg
    27901 agttgactcc aagtcaagca ttttgtatct aatcgaaaaa tttttatcat taacaatcat
    27961 atatctggag tttatacaat gctcttctct taccaatttt tgaaatattt aaataataaa
    28021 gaaattactc tattccaaat aagatagtac ccaagtattt ttcacttttt tctaatgttg
    28081 atgctcataa ctccgttcca agtcacacac ctttcgctta tgggtttgat gagtttctag
    28141 gtcagcatca atttcaatgg taatattttg aaaaccacaa tcttttagga aaattcgaat
    28201 agactcttta caagtttcca tatgttccat ttcttttaga caaacatgga caatggcatt
    28261 tttttccaaa gcatccatag tccagagatt aagctgatta aggctggcca cattgtccaa
    28321 tcgttccagg ccactcttta cttgcttgat atcaagacct tctggcacag catccaagaa
    28381 aatcttgagt gtagaccaaa aacgtgaaag ggcttttgaa agaataaaga aagaaatgac
    28441 aagggacaaa agaggatcta ggatatacca gtccgtaaat cgaagaacaa tcgccatcag
    28501 gataacagct acccacccta gcgtatcttc cagaaaatgc agactcagaa tagactcatt
    28561 ctttgtcttt cccttaccaa ccaccagact cgctaacaga ttgatagtaa tcgcaataat
    28621 tcctaaccag agaatcccct catcattgac tggttgcgga tgcaaaatct tcgtgacatt
    28681 ttccaaaatg actagaacag agcctgttac gagaatcaca gctgttacca aggctcctag
    28741 caggctaaat cgcttatagc ccaaggtgta ctgattgtct tcttcacgat tggagattgt
    28801 ttctagaaaa gctgatattc caattgcaat cgcatctccc aagtcatgca cagagtcagc
    28861 aagaacagcg ctagaaccaa atactccacc tgcaataaac tcaacaatgg cataagtcaa
    28921 atttaagaaa aaagccaccc aaacagcata ttttgccttc atatttctca ttcctttgtt
    28981 ataatagatt tatgaacacc ttgttcatta tcattatcca ctaaaactca aagaaaggat
    29041 agaagcaaaa cgtcagcttt attcagttct gaacaatttg ccttaagtgt ccatatgact
    29101 aacattgacc gccgtatcag caaaaccaaa aaagccatct atcaagcttt tatacaactt
    29161 ttgaatgcta agggctacga ggccactact gttcaggata tcattgatct cgcagatgtg
    29221 ggacgatcca ccttttactg tcactatgag agtaaggagc ttcttctgga ccagctctgc
    29281 cgctacctct tccatcatct ttttgaaaga gagcaagcca tttcaaccga ggactacctc
    29341 gcccacctct ttctccattt tcataaaaac caagaccata tcaccagtct gctattttcc
    29401 aaaaatgact acttcctccg tcaactccat aaagagctag aacaccatgt ctattccgtg
    29461 ctagctgata atttaaaaga agcccaccct aatctgccta cttcttacct ccaacacttg
    29521 gtcgtgtcca actttatcga gacattgacc tggtggctca aaaaaggtca agatttcaca
    29581 gaccaggaag ttgtccaatt ttatctagac cttctcattc ctaaaaattg aatatagagt
    29641 aaagcttcag ttgtcttatt tctaggttac tgagtttttt atcttttcaa caacaaaaga
    29701 ggacccgccg atcctctttt tcatactata aatccttgat tatcaactat atctgtttta
    29761 atcgaaatct caaaacagca ctttcaaaca tcttttccta gttaagtaaa tcagtatttt
    29821 gcttagctgc cttgctccat tgataccaac caactagact gttaatgaga taaattagat
    29881 atttcccttg aatttgcagg ctttctcccc accagagata gattgaaaag acattggtag
    29941 ccgcccagaa tatccactgt tcacggtaaa cagctgtcat gaggatttgc cctaccccat
    30001 tggttgcatc tgtgattgaa tcacgatagg gacgattggc accaatagac tgataaatga
    30061 agccaaaggc caaccaccaa agcacactaa tggaaagata ctttgtccag cccttgccgt
    30121 ccagtttacg cgcgacaaac tcctgctttt ccttcttaaa ctgtgcctga taaatccaaa
    30181 ctagaagtcc aattggctgc atgactgtga agtaaagtgt cgtcagcacc tcaccataaa
    30241 agcctttctg tagggccaaa ataaggtaaa taacagagtt aatcaagcca aaaagataat
    30301 tacttgctcg accttccgat acaaagatta cacagataat ccctgtcaag ctacaaatca
    30361 tcccaatcca gtcaacaata cgatgttcgt aaaccaactc cagccagaga ggaaaacttc
    30421 ctaaaaccag caaataaatc cactgggcaa aactacgatg ggcaaagagg tcatcccaga
    30481 tagccttcat agttcctgaa aatcctaaat cagccatagc cgcaaccata cgacggtaac
    30541 cacctgacat ttcacctagg gttgttttga tattttcaat tttcttttgc aaataagtat
    30601 gcatcatttc tccttttgtt tttaaagagc cgtgtctgga tagactttcg gacgcaacgc
    30661 tctattagat aatgaactgc ctatacacaa gatttctaac cttagtcgac atgagctgaa
    30721 acctcttatt tgttaagtag ttcacaaaat attatacacc tattttatga atagtcaact
    30781 gtctttacag taaaatttta gaaaatcatg aaaattttct ctttctttcc attttaagtg
    30841 acattcagtc attctcacat caaaaaagcc cagacgaaat tgtctgagca ttcttttatc
    30901 tagtcgttta aggaagttga gttcagtatg tttaaagtct ctgtcccatc atttcttcaa
    30961 caaaccttgt tcttggagaa actccttggc tacttgcttt gctgacttgc cttcaacacc
    31021 gacttgatag ttaagctggc tcatctggct ttctgtaatc ttaccagcca atttattaag
    31081 aacagtttcc aactctggat gtttcttgag aagagcttct ttcatgagtg gagccccttg
    31141 ataaggtggg aagagttgct tgtcatcttc caagacctgt aaatcataac gctccaattc
    31201 cgcatcagtc gaataggcat ctgtaatttg aatttcacct gactgaatcg cttgatagcg
    31261 aagagcaggt tccaaggttg aaacattgag attgagacca tacattgatt gcaagccctt
    31321 atttccatct tcacggtcgt taaactcgag tgtaaagcct gccttcaact gaccttccac
    31381 ttttttcaaa tccgaaatgg tcttcaagcc atattcttgc gcaatctttt tcggaacagc
    31441 tacagcataa gtattttgat aagacatggg tttaagatag gctagatgat cctgtttggc
    31501 aatgccatca cgcgccacct gataaacctg ctctggctca tgactcactt taggtgatgg
    31561 ttgaagcaaa ctttcagtca ccgtaccagt aaattcagga tagatatcaa tgtctccgct
    31621 tttcaacgct tcataaagga aagttgtttt cccaaagtta ggcttaacgg ttgctgttag
    31681 acttgtattt tcttctatta aaagtttata catattagcc aaaatttctg gttctggacc
    31741 aattttccct gcaataatca cgttttcttt ctctttttga accaagaggg ctggactata
    31801 agatagaccc agcaataccg tcaccaaggc aaaacctgag aaaatcgtcc gtaattttgc
    31861 tttttccatt acttttagta ggaagttaaa ggcaatagca agcactgcag aagaaagtgc
    31921 cccaatcaaa atcaaactgg cattattacg gtcaattccc aacaggataa aggaacccag
    31981 tccccctgct ccaatcaagg ccgccaaggt tgccgtaccg ataatcaaaa cagctgccgt
    32041 ccgaatccca gacatgataa caggcatggc aagtggaatt tcaaatttct tgagacgttc
    32101 ccatctggtc atcccaaagg caatcccagc ctcttgcagg ttcggatcaa ttcccttcag
    32161 cccagtgata gtattttgca aaatagggaa aatcgcataa atcactagag ctgtcaaagc
    32221 cggcaaggtc ccaattccca tcaaagggat aaagagcccc aacaaggcca gagacgggat
    32281 ggtctggaaa atacctgcaa tctgcaagac ccagtcggcc agcttctcat gatagcgaag
    32341 aaaaacagcc aagggaatcg caagcaaaat agctagtaac aaggtcaaaa gtgacaactg
    32401 caaatgttga gatagagctg tcaaccaatc actaaaacga tcctgaaaag ttgcaattaa
    32461 attagtcatg aacactacct ccaaacaagt ctgctacaaa gtctgttgca ggcgctttta
    32521 aaattgtctc gggattcgct acctggcgaa tttctccatc ctgcaagaca gcaatacggt
    32581 ccgccaactt caaggcttca tccgtatcat gggttacaaa aatcgttgtc atcccaaact
    32641 ctttatgcaa ttcttttgtc agaacctgca actgttttct cgaaatagca tccaaggccg
    32701 aaaagggttc atccatgagg aaaatcttgg gctgaccaat catagctcgg acaataccga
    32761 cccgttgctg ttctccacca gataattcac taggtaagcg atgcccatac tcggctactg
    32821 gtaaaccaac cttagccaaa agctcttctg ttttcttcgt aatttcttcc ttgctccacc
    32881 ccttcatttc aggaatgaga gcaatatttt ccgcaactgt tagatttgga aaaagagcaa
    32941 tagcctgtaa aacataacca gtagaaagac gaagttcacg ctcatcatag tctttgatgc
    33001 gcttcccatc catataaata tttccatcag ttggttccaa aagacggtta atcatcttga
    33061 gcatggtcgt cttacctgac ccagaaggcc ctactaaaac cataaattcc ccatcctcaa
    33121 tctgtaagtt gacatctctc aagacatcct tttctgtgta gcgcagtgct acatttttgt
    33181 attcaatcat tctttgtcct caatttaaaa cttccctcga ttggtcaagt cttctacctt
    33241 aggcatgact tccttattat cccaatgctc cacaattttc ccgttctcta aacggaagat
    33301 atcgtactgg gcataagcaa cgccatcaat ctgagtctga ccatagctaa ccacatagtt
    33361 tccttgtcct aagagttgga aaacaaagtc aaaagtgaca ctatattcag ccacatagtt
    33421 tttataagca gcacttcctt gtccaatctc atgattatgc tgaatcaaat cgtctgccac
    33481 ataatcactc cactgctcta gctccccatt ttggaaaatt tctgtcaaga aacggcgaac
    33541 cagcttttta ttttctgctt tcttgtccaa atccttgatt tcaaaatctc caaaaatttg
    33601 atctagttgg tcattttcag gtgttcgata gtagtcaatg acatcccaat gctcaacaat
    33661 acgaccattc tcatccgcac ggaaagtatc cgtcgtcacc cattgagctt ctccaccatt
    33721 cagatattga tgaacatgaa caaagaccag attgccatcc tcaatggtgc ggacaatctt
    33781 aatctgacgc tctggatgac gctcaaagaa atctgcaaag aagactgcaa atccttcttt
    33841 cccgtcagga acacctgtcg aatgttggat ataggtatcc cctacagact gggcttgagc
    33901 ctcagcaact cgtccgtctt gaatggcatg gatgtatagg ttgtgagcat ttttcacttg
    33961 ttgtgacata ttctaaacct catttccctt ctctttcaaa ttcgccaaaa ttctttcttg
    34021 aaaaccttca aattggtgaa tttcttcctc tgaaaatcct ttgtaaaaga tagtatccaa
    34081 tttctgactg acacgatgcc ccacttcttt ctgggacttg cctaactccg ttaaaactaa
    34141 atacttctta cgcttgtctt ttccacacgg actaacaatt acaagctttt gttcctctag
    34201 cttttttatc atagtcgtca gcgtattatt cgcaagccca gtcgcaagcg cgatatctgt
    34261 cgcagttgcg cagccagttt cactattcca taaaaccgct aaaatcttgc cctgttcacc
    34321 cctataaaga gcctcaggat cttgactcag taacttttga aaaatccgcc cattcaacaa
    34381 acgaatatga tgggctagca aatgactatc tttcataaca cctccaattt atttcgatgt
    34441 cgaaatgaat aaaataattg taacactcat cgttctaact gtcaactatt tcgatttgga
    34501 aataattttt gataattatt cacaccacca tactccggct caactaactt ttaacgagag
    34561 tttctaaatt ccttcgtcct ccagtctaca aaagccttcc atccgtacta tcctattttt
    34621 tatgagggga cacatttttc ctatcagatc atttatttta aagatagaag taaatcataa
    34681 ttgcttccat ctgttctttt atagtatatt gaagttagac tagggcactg tatcttctaa
    34741 aacattgata gaaagcgatt tgaatttccc aatcaatttg ttcgtattta taacattttg
    34801 aaactggaat aggacgttat gactgctaaa atatttctat aaattcattt gattttccta
    34861 atcaatttgt tcatatctta tttcattccg ctataatttc accttaccct atctttttcg
    34921 tagcaccctt caaacagcct atcccctacc gtttgacgat tcctcacttc actccacttc
    34981 cattacagaa gtttcttcac tactatggtc tcggctgact tctcatgatt ccttgttact
    35041 actatttgaa cgctcacgag ataggtctta taaaaaatgc tttgatccac aatggaatca
    35101 aagcatttta aaaagttcct catacataag cgcagaagtc gcagttcctc tgtacttggc
    35161 ttcttctctt ttgataaagc gagccaagtt gagcaactca ggtgctggat gtttgggatt
    35221 taggagcaat tcacgattga ccaggcctga gagacgaact gcctgcaatt gctcatttgt
    35281 agtaggcagt tttttagtag tctctaggag agcagcaact aaatcttcac tcaaatcatg
    35341 tcgagcatga ttgtaaagat cttttataag gctttctagg tttggttcta ccatccctac
    35401 cacctccctt atggtttaat aatgtttaat caaatcaacc gttgaacgat ccaatttctt
    35461 caccaaggct tgtaagaaag cttgcgcttc taggaagtca tccattgcat agagggtttg
    35521 gtgagaatgg atataacgag cgcagacacc gatagttgtt gatgggacac caccattttt
    35581 cagatgagct gcacctgcat ctgttccgcc tttaccacag tagtattggt acttgatacc
    35641 agcttcttca gccgttgtca aaaggaaatc cttcatccct gggagaagca agtgacctgg
    35701 atcatagaaa cgaatcaagg ttccatctcc aatcttgcct tgaccaccgt agacatcacc
    35761 tgctggtgag caatcaactg cgaggaagac ttctgggtca aacttggttg tagaggtatg
    35821 agcgccacgc agaccaactt cttcttggac gttagaaccc agatagagtt cattgccgag
    35881 tttttgacct gataaagctt cagctagctc gcttaccatg aggacaccgt agcggttatc
    35941 ccaagctttt gagatgatat ttttttcatt ggctgtcaaa attgcagaac tatctggtac
    36001 gatggtatca ccaggacgga tgccaaaact ttctgcctca gccttgtccg caaaaccacc
    36061 atcaaaaacg atatcggcaa tggctggcat ggttggtccc ccctttccac gagtcaaatg
    36121 cggaggaaca gaacctgaaa tcacaggaat ttcatgacca tcacgagtca agagtttgaa
    36181 acgttggctg ctaaccacca tggggttcca gccaccgatt tctacgacac ggaaggtacc
    36241 atctggcttg atttcgctga ccataaaacc aacttcgtcc atatgagaag cgaccaagac
    36301 gcgcggtgca tccacagctt ctgaatgttt gataccaaaa ataccaccca agccatctgt
    36361 caccacttca tccacatgcg gtgtcaactt ttcacgaaga taagcacgga caggcgcttc
    36421 atgacctgag actgcagcaa gttctgttac ttctttaatt tttgaaaata atgttgtcat
    36481 ttcagttcct tctttctttc atccatttta ccacttttta taggagaagg atagtgggaa
    36541 ggtggatttc taagttagta tcttagtcct gctctatctt agaaaaggat agtattctct
    36601 tgcatgtagt gcaaaatcta gtaaacattc caaaattaac tcgaatattt atttccaaac
    36661 aaaaaaacaa tacaccatca aagttgtttg gatttttcat gaaatttaca gaaaatagtt
    36721 gacttccctt tcttctttct ttaaat
//
LOCUS       DAVKMO010000016        34835 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVKMO010000016 DAVKMO010000000
VERSION     DAVKMO010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34835
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.016"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(268..629)
                     /locus_tag="VW361_000919"
                     /pseudo
     CDS             complement(268..629)
                     /locus_tag="VW361_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
     gene            637..717
                     /locus_tag="VW361_000920"
                     /pseudo
     CDS             637..717
                     /locus_tag="VW361_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(1615..2304)
                     /gene="rplA"
                     /locus_tag="VW361_000921"
     CDS             complement(1615..2304)
                     /gene="rplA"
                     /locus_tag="VW361_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU9743986.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2512..2937)
                     /gene="rplK"
                     /locus_tag="VW361_000922"
     CDS             complement(2512..2937)
                     /gene="rplK"
                     /locus_tag="VW361_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU9743987.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            complement(3246..3962)
                     /locus_tag="VW361_000923"
     CDS             complement(3246..3962)
                     /locus_tag="VW361_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU9743988.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(4043..4827)
                     /locus_tag="VW361_000924"
                     /pseudo
     CDS             complement(4043..4827)
                     /locus_tag="VW361_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(4847..5276)
                     /locus_tag="VW361_000925"
                     /pseudo
     CDS             complement(4847..5276)
                     /locus_tag="VW361_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372219.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
     gene            complement(5278..6315)
                     /locus_tag="VW361_000926"
     CDS             complement(5278..6315)
                     /locus_tag="VW361_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU9743989.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFGFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(6413..7738)
                     /gene="brnQ"
                     /locus_tag="VW361_000927"
     CDS             complement(6413..7738)
                     /gene="brnQ"
                     /locus_tag="VW361_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU9743990.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(7909..8001)
                     /locus_tag="VW361_000928"
     CDS             complement(7909..8001)
                     /locus_tag="VW361_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9743991.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(8044..8196)
                     /locus_tag="VW361_000929"
     CDS             complement(8044..8196)
                     /locus_tag="VW361_000929"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9743992.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(8356..8934)
                     /locus_tag="VW361_000930"
     CDS             complement(8356..8934)
                     /locus_tag="VW361_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU9743993.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(8988..10388)
                     /gene="pepV"
                     /locus_tag="VW361_000931"
     CDS             complement(8988..10388)
                     /gene="pepV"
                     /locus_tag="VW361_000931"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU9743994.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(10401..11006)
                     /locus_tag="VW361_000932"
     CDS             complement(10401..11006)
                     /locus_tag="VW361_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU9743995.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            11177..11977
                     /locus_tag="VW361_000933"
     CDS             11177..11977
                     /locus_tag="VW361_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9743996.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKISVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(12159..12992)
                     /locus_tag="VW361_000934"
     CDS             complement(12159..12992)
                     /locus_tag="VW361_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU9743997.1"
                     /translation="MNHKIAILSDIHGNVTALEAVIADAKNQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLHFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQGHNLELLASLIEKHGYVEDVKDYFDF
                     L"
     gene            complement(12982..14826)
                     /gene="uvrC"
                     /locus_tag="VW361_000935"
     CDS             complement(12982..14826)
                     /gene="uvrC"
                     /locus_tag="VW361_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU9743998.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDETYFKSMAQEVSDFLKGQDNKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVIFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(14866..15567)
                     /locus_tag="VW361_000936"
     CDS             complement(14866..15567)
                     /locus_tag="VW361_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU9743999.1"
                     /translation="MRWLFRLIGAFFFFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(15646..16878)
                     /gene="murN"
                     /locus_tag="VW361_000937"
     CDS             complement(15646..16878)
                     /gene="murN"
                     /locus_tag="VW361_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU9744000.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(16883..18103)
                     /gene="murM"
                     /locus_tag="VW361_000938"
     CDS             complement(16883..18103)
                     /gene="murM"
                     /locus_tag="VW361_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU9744001.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(18215..18994)
                     /locus_tag="VW361_000939"
     CDS             complement(18215..18994)
                     /locus_tag="VW361_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU9744002.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(19063..20724)
                     /locus_tag="VW361_000940"
     CDS             complement(19063..20724)
                     /locus_tag="VW361_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9744003.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(20899..23121)
                     /gene="recJ"
                     /locus_tag="VW361_000941"
     CDS             complement(20899..23121)
                     /gene="recJ"
                     /locus_tag="VW361_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU9744004.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEERENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNTVLPEGVPVLDFPGELPNLAASEAVVVKNIPESITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            23398..24156
                     /locus_tag="VW361_000942"
     CDS             23398..24156
                     /locus_tag="VW361_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9744005.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            24167..24961
                     /locus_tag="VW361_000943"
     CDS             24167..24961
                     /locus_tag="VW361_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9744006.1"
                     /translation="MKKKFFLSALLISLFGLVAAKPVQANTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIHYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSD
                     YGIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            24974..25651
                     /locus_tag="VW361_000944"
     CDS             24974..25651
                     /locus_tag="VW361_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9744007.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            25661..26320
                     /locus_tag="VW361_000945"
     CDS             25661..26320
                     /locus_tag="VW361_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9744008.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            26557..27681
                     /locus_tag="VW361_000946"
     CDS             26557..27681
                     /locus_tag="VW361_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU9744009.1"
                     /translation="MEFSMKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSL
                     TFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNL
                     AIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFL
                     VGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQF
                     AFLKIFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYG
                     HMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNY
                     AQKNPNFELHLIDSTKDGYLNFEQKKCPNMQPSICVVLFL"
     gene            complement(28079..28960)
                     /locus_tag="VW361_000947"
     CDS             complement(28079..28960)
                     /locus_tag="VW361_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU9744010.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(29101..30429)
                     /gene="vncS"
                     /locus_tag="VW361_000948"
     CDS             complement(29101..30429)
                     /gene="vncS"
                     /locus_tag="VW361_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU9744011.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     HTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKNRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(30426..31082)
                     /gene="vncR"
                     /locus_tag="VW361_000949"
     CDS             complement(30426..31082)
                     /gene="vncR"
                     /locus_tag="VW361_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU9744012.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(31131..31214)
                     /gene="pep27"
                     /locus_tag="VW361_000950"
     CDS             complement(31131..31214)
                     /gene="pep27"
                     /locus_tag="VW361_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU9744013.1"
                     /translation="MRKEFHNVLSSGQLLTYKRPARDYNRK"
     gene            complement(31395..32774)
                     /gene="vex3"
                     /locus_tag="VW361_000951"
     CDS             complement(31395..32774)
                     /gene="vex3"
                     /locus_tag="VW361_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU9744014.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(32826..33473)
                     /gene="vex2"
                     /locus_tag="VW361_000952"
     CDS             complement(32826..33473)
                     /gene="vex2"
                     /locus_tag="VW361_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU9744015.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(33486..34763)
                     /locus_tag="VW361_000953"
     CDS             complement(33486..34763)
                     /locus_tag="VW361_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9744016.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9902 a         7904 c         6461 g        10568 t
ORIGIN      
        1 ttttagcaat tgtttcgtac tattttagat tcagtctact atacataaac taacctcctc
       61 attattagca aggcttctac tgattataac ctaattctta gactacttca agactaactg
      121 tccaataata atctacagat aaatcatcca ctcttaatca aattttattc aatccatcta
      181 ctcattccca aaaggttgct gtataatgca agacattttt cttactgctt ttacttttcc
      241 ttaccctcaa tttagtgagc taataaatta ttcttcttca aaaggttgag atttatctag
      301 taactctaaa acattaatgg taggtagcaa cattgcttca ctgctatcaa ttgccgaaac
      361 tattgaaaca atagaacgta aataaggaca aagaatagca gtaccattta cgtatagaat
      421 atcggtgata ttttcatcta tatttatttc aaaatatcct attacagtta cagatatttt
      481 ttcatggcat ctttgtcaac taaagaaaca ctaagtttta cggctccatg actataatca
      541 tctgtatgac caaccttaac tatgggatat aatatatcga aggtaaatgt gaacaaactg
      601 attagggaat ttaaaccaac ttctaacaat gtgttatact caatgaaaac caaagagcaa
      661 actaggaaac tagccgcagg ttgctcaaaa cactgttttg aagttgtaga tggaactgac
      721 gtagtcagct caaaacactg ttttgaggtt gtgaatggaa ctgacgtagt cagttcaaaa
      781 cactgttttg aggttgtgga tggaactgac gtagtcagct caaaacactg ttttgaggtt
      841 gtggatagaa ctgacaaagt cagctcaaaa cactgttttg aggttgtgga tagaactgac
      901 gaagtcagta accatacgca cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa
      961 gagtattaga aagctcgatg gactattcca gattcattcc actagatttc gaaatcgagt
     1021 aggggataat ctctagcccc tctcacacca ccgtacgtgc cgttcggcat acggcggttc
     1081 aactaacttt taacgcatgt cgttcaaggt aataatccaa acacgaaacc agtccacgtt
     1141 tttcaaggac tggttttgat atagcacgtt taagtaccga cttctgagct actatagtag
     1201 attgaaacta gaatagtaca cctctacttc taaaacattg ttagaaatcg atttgactgt
     1261 cctgaacgat tcgtcctatt cttatttcat tttactataa ttgatagtgg tcgccccagc
     1321 cagatacctt atccgctata taggccttat tatcacgttc ctgttcgtag agccacgatt
     1381 tcgctatccc ttcctctgac gattcttatt tccagcgtca gacttaaaac ggtctatccc
     1441 cagaccgttt taatccgcta cctcacgata gtcagacttg ggaatcgcta ttgggttcac
     1501 cagtagtagg tgcccaccga ggactcacac ctcagatata cgacatgccc gtcgtacatc
     1561 aaaaaaagtt gagacatagc gtcttcaact tttttacatt actttaacta ctgattaaag
     1621 tgagtttacg tcaactttga taccaacacc ttgagtagtt gtgatagtca agtttgttac
     1681 gtaagttcct ttagctgtag ctggttttgc tttttggatt gtttcgttga aagctttaaa
     1741 gttttcaacc aatttttcag cttcaaatga tactttaccg atgattgctt gaacgttacc
     1801 tgcacggtca gcacggtaag tgattttacc acctttagac tcttcaactg ctttagcaac
     1861 atccattgtt acagtaccag ttttagggtt tggcatcaag ttacgtggtc caaggacacg
     1921 tccaagacgt ccaacaagag ccatcatatc aggtgtagcg ataactacgt cgaagtccaa
     1981 ccaaccgtcg ttgattttag caacaaggtc atcttcacca acaaagtctg caccagcagc
     2041 ttttgcttct tcagcttttg caccacgtgc gaaaacaaga acacgtgaag ttttaccagt
     2101 accgtttggc aataccattg ctccacggat ttgttggtca gcttttttaa cgtcgatgtt
     2161 caagttgtaa gcaacttcta cagttgcgtc aaattttgca aagttagttt cttttgcaag
     2221 agctacagct tcttctacgc tgtatgcttt tgtgctgtcg attttctcaa gagcagcacg
     2281 aagttgtttg ctttttttag ccattttcta ttctccttgt aagtggttca atcgattttc
     2341 atctcccacg tcacttctcg aaatgatgaa gtcttgcggg ttttcagtct actatttttc
     2401 tcctcctacg gccttaagct cccttgctgt acccaagtac aagcctcagt cacttgccta
     2461 gtatgaaaag caactaatag actgctgtga gattttctac tgtgttattg attagtcaac
     2521 aacagtgaat cccatagaac gagcagtacc ttcgatcata cgcattgcag actctacgtt
     2581 tgctgcgttc aaatctggca tcttagtttc tgcaatttct tgtacttgtg cacgagtaac
     2641 tgtagcaact ttagttttat taggtgtacc tgatcctttt tcaacacctg cagctttttt
     2701 caaaagaaca gcagctggtg gtgttttcgt aacgaaagta aatgatttat cttcgtaaac
     2761 tgagataaca actggaatga tcataccagc ttggtcagct gtacgagcgt tgaactcttt
     2821 tgtgaatccc atgatgttga taccagcttg accaagagca ggtccaaccg gtggagctgg
     2881 tgtagcttta ccagcaggga tttgcaattt tacaagtttt tcgacttttt tagccatttt
     2941 taaatcctcc tttgtggttt tggcggtaat tagagatttt tacctcccac aagtatgttt
     3001 ttcacatacc catccattat acactattta tctggaattg caagagaaaa gtttattttt
     3061 tatactcaat gaaaatcaaa gagcaaacta ggaagctagc cacaggctgc tcaaagtaca
     3121 gctttgaggt tgcagataaa actgacgaag tcagctcaaa acactgtttt gaggttgtga
     3181 atagaaccga cgcagtcagt aggtaaggcg acgctgacgt ggtttgaaga gattttcgaa
     3241 gagtattaat cgacgtagtc tccgccttca aagccatagt attcttccaa actgagacca
     3301 cttgcagcaa tttctttagc ttcttttcct acataacgca ggtgccattc ctcagccata
     3361 tagcctgttt ccttttcctt gcctttgaga taacggacaa caaagccata atcagctgca
     3421 tgatccaaga gccattgggc tgctttttct tctgtcacca aatcaccatc agtcccaatc
     3481 acatcaaagg ccaagcctgt ctggtgttcg ctatagccag gacgggcaga gtaacggtca
     3541 gctgctgcct ttccatcttg gttgacataa tcttgataga gcttggtctg agtttcataa
     3601 cttctaaaac cactgtaatg atcactaata gggaaacctg cctcttgcat cgctttgatg
     3661 agtttgacca actcagcctt ggctgttgga ttttccccgg gattatagtc tttcgacaaa
     3721 ggataatgtt tattggctac gatgatttcg tcgtattttc cttggatgct gtagtaatca
     3781 cctttattga ccacttctgc ttttttctgg gcagcccctt gagacttact gccgactgtc
     3841 ccatcagctt tggctgtctg ttctgtctta gctgtgccat cttcattttt tgctttttct
     3901 tgtgaacaag ctgctagact caaggctagc aaggctgtca cgacaaggta tcttttcttc
     3961 atttctactc ctttatttct aatagtttat ctacttctga tgataaacgt ttgactaatc
     4021 ttttaataga cttcctgcaa aactagaatc ctagttcatg attgataata ccagcaatca
     4081 aattcattcg taatccgaag cgtttacgat gatttcgata ggttgttgaa aacattttaa
     4141 acgtttttac tttggcaagg atgttctcaa ccttgcttct atccttagat agcgcatggt
     4201 tataggcttt atcttcagct attagcggct tgagtttgct ggatttacgt ggagtttgtg
     4261 cttgaggata tatcttcatg agcccttgat aatcactgtc agccaagatt ttaccagctt
     4321 gtccgatatt tctgcaactc attttgaaca acttcatatc atggcaatag aaacaattct
     4381 cccttgactt gtgacaatcg cttgagcctt catagcgtga aatttctttt taccagaatc
     4441 attcgctaat tgttttttag ggcgattgat ttgtacttcc gtcgcatcaa tcattaccgt
     4501 gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa gagttacttc
     4561 aacccatcgg ctccgacgga ttaagttgct ttcgtggata ccaaaatcag ccgcaatttc
     4621 ttcataagtt cgatattctc gcacatattg aagagtggcc ataagaaggt cttctaggct
     4681 taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt ttaatacagc
     4741 taacatctct tcaaaagtcg tgcgttgaac accaacaaga cgcttaaatc gtgcatcggt
     4801 tagttgttta cttgcttcat cattcataga actactatac catattttat ttcgcaggaa
     4861 gtctgatctc atccggtttt gcttgacggg tttctgcggt tatttcttca aaagggaccc
     4921 accagactgg cccacagccc ttgagaccgt ggccattcat atcacctctt cgtctaggga
     4981 aaaggtgcca gtggagatgg gcatcgccat ttcctagaag ttcaatattc attttctcag
     5041 cagtaaaggc cttggcaact gcctcttgga ctaaactcat ttcttctaga aaatggagtc
     5101 ttgtgtcctt ttctaaaatg gtgcaattcc gtgacatgtt ccttggctaa aaagagacta
     5161 tagcttgcaa aatactgatg gtctccaatc acaagatagc ctgtttccaa ctctttgaca
     5221 aagtagggat tttctccctt cttgatgagc tcaattctct ggcaaataag gcacatatca
     5281 atctactaaa ttgcttctaa gataggcatc gaccattcgt tctgttgcga ccaccgagtc
     5341 aatatgagtg cgctcataag aatgactaga ctcgataccc gcaccaagaa gggcatgctt
     5401 gacctctgcc cctgcagaca tagccgctga agcatccgaa ccataaaatg gatagatgtc
     5461 cagcttaaaa ggaatatctt gctctttagc caaggcaacc aagtgttgac ggaagtcata
     5521 gtgataagga cctgaagcat ccttgacaca gatagatact gtgtactcat ctgtctgctg
     5581 gtcatctccc atagctccca tatccacagc cagatattct actacctgag caggaatgtt
     5641 agaattagca ccatgtccta cttcttcaaa aactgaaaaa ccaaaatgag ttgttactgg
     5701 caattcaatc ttctctttct tataaatacg aagcaggttg agcaaaatcg ctgcgctgac
     5761 cttatcatcc aaatgacgag acttgataaa acctgtatca gtcacaacag ttcgtggatc
     5821 gaagctgata aaatcaccga cctcaatccc aagagcacga gtttcttttt cattgcttac
     5881 ttttacatcc aaacgcactt ccatattgtc ctgcgtgcgt tctgcagttc ctgcatcctt
     5941 gtagacatgg caagaagttt ggtggatgag gatggttcct gatacctttt gacctgtgct
     6001 agccacatga acggtacagt tttcaccttc aatcatgttc caaggaaaac caccgatacg
     6061 gtccaattta agacgaccat ctggtttgac agcacgaaca atagcaccca gcgtgtccac
     6121 atgggcagtc acatagcgat gttgctcatc attttgacct ttgatggtca cattgacacc
     6181 acccttggct gtgcgaactg gctggtaacc aaaaccttct agagtcttga ctaaataatt
     6241 cgaaatttca cgagtgaagc ccgttggcga tgcgatggct gtcagttctt tgatatattc
     6301 tactgtttga ttcatttctt cacctctttc gctacctatt ataacacatt tatcatcgga
     6361 taaaaaaaga aaatcactcc tgtagacttg gctacaaaag tgatttaagt gattattcca
     6421 tttcaaaaac atcgctttct tgcttgtttg gtagaaccaa tgagagcaag attccaacaa
     6481 tggctggcac caaccatggg agagatgcct tggcaaaagg aagaacgcta acaagatttg
     6541 caagaaactc aaccttaaac gagcttccta gtacgcttgc aatggcaata actgtaacca
     6601 cagcaattgt caactgcata cctggttttg aaagggcaac aaatttgttg acaatgacaa
     6661 tcataacgat agcaatcgtg attgggtaca agataaccag tactggaatt gagtacttga
     6721 taatcgcatc aagacccaaa ttggcaatag caaatccaat caaggtaaag gctgtcgcat
     6781 aaaccttgta gctgatttgt gggaagcgct cattaaagaa ctcagctgtt gacacaatca
     6841 aaccaacagt cgttgtgaag caggttacgg taaccatagc tgcaaggaag agttgagctg
     6901 ttgagccaaa gatttcttga gtggcttgtg acaagatgta aacacctggt gttccaccct
     6961 tcatcgcttc agctggtact gggaaatgat ttccaagaaa acctaaaccg atgtaaagag
     7021 cgctgaaggc aagggcaaca acgataccaa caacccaaat agttgaaatg tattctttct
     7081 tacttgaaaa tccaagttgt ttcaaggttt gaactgcgat tacgctaaag gccactgagg
     7141 caagggcgtc caaggtattg taaccttcta ggaaacctgt accaaaggca gaagcttgat
     7201 aagcagctga agcagcttga ggacttgttc caccatattt gatagctccc agaacgacca
     7261 agataacaat caaaattgca aagactggcg ttaaaatacg tccaatgcgg tctaagattt
     7321 ttgatggatt aagcgaaatc aaataggctg ccgcaaaata cagaaccgta aatacaatca
     7381 agccaagtcc tttatttgca tccgacaaaa gggggctaat ccctacttcg taagctgttg
     7441 tagcagtacg tggggtagca aagaatggac cgattgacaa gtaaagaact gagaggtaaa
     7501 gagtcgcaaa ccaaggcgct atcttcgttg aaatctcgta gatatatcct ttaggattta
     7561 gcgttccaat aataagggtc aagacggcga taccaacgcc tgaaaagaca aaacctgcga
     7621 tggcaggaag aaaatgttct ccagatagag cacctagaga aggcggaaaa atcaagttcc
     7681 ccgcaccaaa aaatattcca aacaggagca aacctgttag ggtacctttt ttagccataa
     7741 aaatctcctt catatttata aaatactgac ctagtatacc acgattagga gtctgaaaaa
     7801 agcatcacga ggcaaatatt aaatgttttc aattttctta aaaataagaa ttatctaaaa
     7861 ataaaactct cctacccagt ccacaccaag taggagaaat gcaaaatttt aaagttcttc
     7921 aaaggctaac atgccaccct ggacattgat aacattataa ccttgttcta ataggaattg
     7981 gcaagcacgc gccgatctca ttccagattt gcaaataata taatgcaagc gatctttgtc
     8041 caattaatca taactatcag ccaattgact aagcggtagg ttgtgggcac cttctaaatg
     8101 aagagctgca aactcatcca cttctctcac atccactaaa gaaagctggt cgttttggta
     8161 aagctggtaa aatgcgtcaa aggctatttc tttcattctt tttcttctaa tactcttcga
     8221 aaatctcttc aaaccacgtc agcgtcgcct taccgtgcgt atgttaccga cttcgtcagt
     8281 tttatctgca acttcaaagc tgtactttga gcagcctacg actagcttcc tagtttgctc
     8341 tttgattttc attgactata aaatggtttt aattcttttt ttcaaatctg gcactacttc
     8401 tgcctcaaac caaggatttt tggccatcca gatttgattt cgtggtgatg ggtgaactag
     8461 cggaaaatag gctggcagat agtctttata gtgtttcacc ctctccgtta ccttcccact
     8521 gattttctcc tgtaaatagt aggcttgggc atattgccca atcaagaggg ttaactgaat
     8581 atcaggcaat tcctgtaaga gctgcggatg ccatttttct gcaaaacctg tacgaggcgg
     8641 aagatcaccc gacttgccat gtcctggaaa gtagaaatcc ataggcaaaa cagcaaaata
     8701 acctgaattg taaaaggtat cttcatccac acctagccag tcccgcaagc ggtcaccact
     8761 tttatctttc cagtaaaggc ctgcttcttg agttttaagt cccggagcct gaccgatgat
     8821 attgatgcga gcagtttttg gcgctgcaaa gagaggctca atgccacgct ctgtatagct
     8881 ggcattctgc gaatccgcca tgatagcctg tttgattctt tcgatttgag acatctactt
     8941 tccctccaaa aagaagtcca agcataagat ctcagacttc tatcgtttta tttgatcaat
     9001 tcgtaaatag cttcggcata aattgctgct gctcggaaga gatcgtccaa ggcaataaat
     9061 tcattggctt ggtgcatggt atcaattgag tctgggaaca tagcaccata ggcaactccg
     9121 cgctctaaca agcgaccaaa ggttccacca ccgatgactt gttcatgacc ttgtaggcct
     9181 gtttgttttt catagacatt caacaaggtt tgcacaagtg gatcttccat tggcacatag
     9241 tgaggggtat gaccatgttc tgatagactg acagaagcaa ctggcaagtt ttctaggatt
     9301 gacttgattt gttctggact tgttcctttt ggatagcgga tgttaagggc aatggtatta
     9361 tcagcacttg tttcatcgaa gcggaagacg ccggcattca tagaaagagc acccatcttt
     9421 tcatccacat gagcaatctt aagattttca ccctcatgat cgttcaagag aattttacct
     9481 gcgatgtcaa ggtagtcttt ggctggacca gcaaagccaa actggctgag gaagagggca
     9541 aggtaagttg cgccattgac acctgaagca ggcatagcac cgtgggctga tttaccaatg
     9601 atcgtcacct tgtatttgcc agcttcttct tggagttctc ctctaagttt gtgttctgca
     9661 acaaaggcat ctagtttagc ttgcaagtca gccaaatcac ctgaaacgac tgctgttgct
     9721 gattctggta ccatattttc acgtaaacca cctgtaaagc tgtgaagacg ggcagcacct
     9781 gtattttctc ctgcaaagtg gaggtattcc gtgatatttc ctttttcacc attgatgatt
     9841 ggaaattcag catctggtga gaaaccgaaa tctggtttgg caagtcctac gtgctcaaag
     9901 tagtagtcca tgtctgccca gcctgattct tcgtctgttc caacgatgaa gcgaactttc
     9961 ttagaagttg gaagacccaa ttctttgatg attttcaaac catagtaaca agctgttgta
    10021 ggacccttat cgtccgaagc cccgcgcgca taaaggcgac catctttgat agttggtgtg
    10081 taaggatctg tatcccaacc gctaccagct ggaaccacgt ccatatgggc aaagattccg
    10141 agaacttctt ctccatcacc aaactcaaaa tgtcctgcat agttatcaac atttttagtt
    10201 ggataaccat cacggtctgc gatttcaagg aatttttcca aggcttttac tggaccaggt
    10261 ccaaatggat gttgggcatc agccttgcta tcatcacgtt ctgagttgat ttccaaaagg
    10321 ctaaacaagt cagccaagag gtcttctttg cgtttttcta cttctgctgt aaaatcaatt
    10381 gctatcattt tttcttcttc ctatcttttt tcgatgattt catctactgg caagcggtag
    10441 cttggttcca atttgtcgtc tgtgtaaccc actgtgatca agagttctgg gcggaaacgg
    10501 tcttcgattt ccaaaacttc attaactttt gatttgtcaa aaccaaggat aatattggaa
    10561 ccaattcctt ggtctgtaag agcgagaacc aagttcatag caaccaaacc tgcattgagt
    10621 gctaggtagt cgctgacttg ttgttcattg tagcgtgcaa attcagctgg caaatttttc
    10681 atgaagtatt gaagttgttc ttctgagaaa ttgttagcac caccaactcg ggcaatctta
    10741 cgagcgcgtt tggcaaggtc tgtatctgta aatagggcaa tggttacagg tgctgatgat
    10801 acctgctcaa agtttgaacc ataagccaac tttgccagtt cagcattttt ctcacgaaca
    10861 actacaaatt tccaaggctg gctgttgtgg gcgcttggcg ccaaggttgc aatttcgata
    10921 gccgtacgca catcttttgg atcaacaggc ttatcagtga aatgcttggt cgcatgacgt
    10981 tttttattta attcaagaaa tttcataatc gatttccttt tctaattcta ctgcttccat
    11041 tctaccataa tttgaaagag cttgcaggga tttttcatga ttaagttttt ctatcacaga
    11101 cataaaagat atatattggt ttatcaggaa agtttctgat aaactagcaa gtactttaca
    11161 tttgaatgga gacagtatga aaaaatttag cctattacta gctatcctac catttttggt
    11221 tgcctgtggg aatcaagcta cacccaaaga gactagcgct caaaagacaa tcgtccttgc
    11281 tacagctggc gacgtgccac catttgacta cgaagataaa ggcaatctga caggcttcga
    11341 tatcgaagtt ctaaaggcag tagatgaaaa actcagcgac tacgagattc aatttcaaag
    11401 aaccgcctgg gaaagtatct tcccaggact tgattctggt cactatcagg ctgcggccaa
    11461 taatttgagt tacacaaaag agcgtgctga aaaatacctt tactcgcttc cgatttccaa
    11521 caatcccctc gtccttgtca gcaacaagaa aaatcctttg acttctcttg accagatcgc
    11581 tggtaaaaca acacaagagg ataccggaac ttctaacgct caattcatca ataactggaa
    11641 tcagaaacac actgataatc ccgctacaat tgatttttct ggtgaggata ttggtaaacg
    11701 aatcctagac cttgctaacg gagagtttga tttcctcgtt tttgacaaga tatccgttca
    11761 aaagattatc aaggaccgtg gtttagacct ctcagtcgtt gatttacctt ctgcagatag
    11821 ccccagcaat tatatcattt tctcaagcga ccaaaaagag tttaaagagc aatttgataa
    11881 agcgctcaaa gaactctatc aagacggaac ccttgaaaaa ctcagcaata cctatctagg
    11941 tggttcttac ctcccagatc aatctcagtt acaataatac tcttcgaaaa tctcttcaaa
    12001 ccacgtcagc tttatctgca acctcaaagc tgtgctttga gcaacctacg gctagcttcc
    12061 tagtttgctc tttgattttc attgagtata agatatacta aaagcgattg gaccagccaa
    12121 tcgctttttt agtttgcatt ggttatttta ggaaactctt acaaaaaatc aaaataatct
    12181 ttcacatcct ctacataccc atgcttttct attaagcttg ctaaaagttc cagattgtgt
    12241 ccctgatagt tatcttcacg acgtagttct tcatacattt cgataaaggg aagccccttg
    12301 gacttggcca attctaactc agcctcgtaa tcataagcaa ctttacgaaa ttggatattg
    12361 accaattccc cgtcttcaac ttctatcacg gcatactggg cacggtgatt ttttaacgcc
    12421 tcccaattaa aatagggcat gccaatcgac cctggattga tgatttgttg cccttgactt
    12481 ccataacgaa gcaactgctt gtgaacatga ccataaactg ccacgtccgt ttccgcatct
    12541 agcagttggt caaatttctc tgtatcattc tcaactagca agtcaccacc atagtttttg
    12601 tcaggtaaat tatgagagat agaaaagtgc aatccgtcaa tttctttctt ttccagcaaa
    12661 ggcaagcttc gtagccagac aatcgttgca ggatccattc gctccatcaa aaactgggtc
    12721 atgcgcattg actggatttc tttcggatat tccaaaccat attcgccatc caagacctca
    12781 aggacacgat catcccaatt gcctcgaaca cttgctgtga taggaaggtc ctttagcagg
    12841 gcgactaagt catttgcgcc tggaccagga agaaaaatat ctcccagaag ccagtattca
    12901 ctgactcctt gatttttagc atctgcaatc actgcttcta gcgccgtcac attgccatga
    12961 atatctgata aaattgcgat tttatggttc attgtggttt ccttccgttt ggtaatctac
    13021 tctttcttct gctacttgag gcaaggcttc tccctgcggg ttcaactttc tttgcacagc
    13081 ctctgcaacg actctaggta ccccaacttc gacaatctca tccacactgg cttccttgat
    13141 tttggtcaaa gacttgaaat gcttcataag attctgcttg cgtttaggtc ccagaccgtc
    13201 aatcccatcc aattgagatg agaaagaatt tttggagcgc agttggcggt ggaaagtgat
    13261 agcaaagcgg tgcacctcat cttggatgcg ttggaggagg aaaaattcct gagaattgcg
    13321 agacaagtcc accacctcaa gcggatctcc aaagagcaat tcatgggttt ggtgcttatc
    13381 attcttttgc agcccagcaa ttggaatatc caagcccagt tcctcttgga taacctgctt
    13441 agcgatattg acttgacctt gccccccatc aatcacaatc aaatctggag gagtcaaagc
    13501 ctcacgctgt actcgaccat agcgtctgcg aatgacctct ctcatgctgg catagtcgtc
    13561 tggtccaaca accgttttta tcttgtactt acggtaatcc ttcttactcg gtttaccgtt
    13621 gacaaagatc accatagccg aaacagggct agttcccatg atattagagt tatcgaagga
    13681 ctcgatacgt actggggtcg ggatttggag caaacgccct agattttcaa tagctccttg
    13741 agtcttttcg acagattttt ctagcaggtt aaatttctgc tccagactaa cacgtgcatt
    13801 ttttatggct agattgacca gttgtttttt ctctccacgt tgaggcttaa gaatcttgga
    13861 atccaccaag gccttgacag cctcttcgtc aatatcctgc ggaatcagta cctcattggg
    13921 aactagatga gatttttctt gatagaattg tcctacatag gtcaaaaaat cctcatctgg
    13981 atcattgaag taggggaaga gattgacatc gcgctcgata agcttaccct gacggacaaa
    14041 gaaaacctgc acacacatcc agcccttatc cacatagtag ccaaagacat cgcgattttg
    14101 caaatctttc gccatgaccc gttgcttggt tcgaagcgtt ccaatagcct gaatcaggtc
    14161 acggtattcc gccgcacgtt caaactccat actttgtgct gctactgcca ttttactctt
    14221 gagatcatcg atgattttgt tatcctgccc tttcagaaaa tcagaaacct cctgggccat
    14281 agacttgaaa taagtctcat ccttcttaca gatggtgtgg gccatgcatt gaccgatatg
    14341 gtaataaaaa cagaccttag agggcgggtt ggtacactta cgaaaaggga atatccgatc
    14401 cagcaaccgc ttgatttcat tggctgcccc cacatcggga tagggtccaa aataaagacc
    14461 tccgtccttt ttgacctgac gagtgataat caagcgtgga tagcgctcat tggtgatttt
    14521 gatgaaagga taggacttgt catccttgag catgatattg tacttgggct tgttttcctt
    14581 gatcaggttg atttctagga gaagtgcctc aatattagac tccgtaacaa taaattcaaa
    14641 atccacaatt tcagacacca gagcctctgt cttggtatca tgacttccac gaaaatagga
    14701 ccgtactcga ttacgcagat ttttagcctt tcctacatag ataatggtgc catttttatc
    14761 cttatgaatg tagcaaccag ggctggtcgg caagagctct agttttgatt taatcaagtt
    14821 gttcatagtt ccattatagc aaaaaaagta gggaaagata gtaccctact cattagtctc
    14881 atatattttt cggaggtttg caacatcctc ttcctggata ccataaaagg aacctgctgg
    14941 ttgcatgaca gacttctcat ctgtatggtc caagccaatc gcatgaccta actcatgttc
    15001 tgccgtatgg acaaggcgtt cataggaata gccatagtat ggattggaca aataataatg
    15061 attcaaccgc accgttacgg acaagaattg ccctgttaag agattagttt gactttccgc
    15121 ctctcctgcc acaggagtgc ctccgtcgtt catctccgta gccgtaatat ccgccttact
    15181 agactcagtc acgagttcaa agttaaaagc accagtttga ttccagttct ggattgcttc
    15241 taaataagcc tcttgaaagc gtgaatccat ctgcggatcc aggtaaatac gagcagaggc
    15301 ctgtggccac cttccttcag aatgctggtg actatctgtc tggcttaact taggcagttg
    15361 ccctgttttc tcccattggt caatactttg ttgaccaatt tttactgacc gttctgcttg
    15421 ctttagcgct ccttgaaaat ccccgttcaa ataccagaga agtccgaaag caagcacaca
    15481 taagagcaca actatccaaa ccagacgcca aaacaaacgc cacacaaaaa aaaagaaagc
    15541 ccctatcaaa cgaaaaagcc agcgcatgtc tctccacctt tctagcaaat aaaaattatt
    15601 ttactaaaag aagctaaaag aaatctaaat actgactttt tcatcttaac gtcctactat
    15661 ttttttgagt aactggatag ctttgtattt taaaggcgat ggatggtaac ggaaagtacc
    15721 cgctttgcgt acaatatagc cattaaaatt ctgtttaaaa cgcaaaacac catcacttcc
    15781 atcaaaaatc ccttgaatgc ctaggaaatt gtatttaggt attccacgtt ttatgctttc
    15841 caacataaca tatttttgaa gcagtgcagg ggcatagaac ttattaaact cagtgtagga
    15901 accactaaag agataagtcg tttcctgagg catataaaca aataaactcc cagctaaaac
    15961 aatatcttct tctccatatt tttcaatcaa gtctcgcgct tctgcttttc gaacttcaaa
    16021 cgtttcaaat tgactagaat attctctcag ttgattttgt tttttctcag aatgaggatt
    16081 tttactcaaa tcaagtcgca acttgtccaa gttttcttct agtttacttt gttcaccttg
    16141 caatttgctc atatactccg aaaaattcaa gcttgctatg agaaactccg cttgttctcc
    16201 aaaagtatca taaaaatgct cataatattc taaactttta tcactatatt ctctacgttc
    16261 agaggtttct tttgttatat tcttaaaaat cgatagttct tcacgtttta actttttcaa
    16321 ccgaatgcca aaggtttcag cctttttcac caagggttta ccctttttgc taaaactttt
    16381 aagcaaactc ttttcagtta attcagttaa atctttatag tataaccaat ctggttctcc
    16441 acctgggtaa cctgttgtta agccatcaaa ttgataacct aaatcagtca aaccttgaat
    16501 aatacttttt ttctcagcat ctattggatt accttggcta tcaaaagttt gataagtttc
    16561 ataaggtttt acaagcaact ctaatacacc attttgcttg gcatattctt ttaactctgc
    16621 ataaaaaact ggaagagcat cttgttgggt ataaatcggc cccgaattga gttccatatg
    16681 cagaccaccc agcatgggca agctataaac cagagctgca acttgaattt ctccttcttg
    16741 tttcaaagca agataaacaa ttcgagcccc tcttttttct agcaaatccc ccatctggac
    16801 agattgcata aaggaacgag aagaaacctg atcagaataa gtctgaaact cttctttcgt
    16861 gagtgttgtt agtgccatat acttactttc tatgtttttt tcttaatgtt ttacggaaat
    16921 caagagcaag tcttaacaga ggatagagag gatgagtggg cattgtaaat tcacccaagt
    16981 attcttcaat cgttggatta aatttttcct taaaatgata aagtccacca ttgagagagt
    17041 tttcaacacc acctaaattt tgccagacca tacctcgctc aaaggcatag cgagccgttt
    17101 cataccatgt taaaattggt gcattgtaac gtttaaaatc atcatccata ccagcatata
    17161 tattgacaga ggtagtacca aattccaaac tcaaagtagc cgctaaagga actctcgctt
    17221 gacctacatc tatatattcc tgcaagaagg tcaattcctc taacaaacgt tctttttcct
    17281 tcttctgcgc ttctactttt gaaattcgag tcgactcagt aaacgtctct tccaaggctc
    17341 tatttttcgc taactgttct tctaattctt gcgaacgttt agaaacatcc aaggtggcca
    17401 aggtgatata ggccttgtcc ttaaaattat ctaacaattt tttataatag gcttcattcc
    17461 tcaaatgaat ctcttttcgc ttctcagttt ttttcatcaa ctccgaaaat gaatctaata
    17521 gttccagtcc accatattga atctcaagcc ctttgtttcg tgctgttcga atagcctgtt
    17581 ttgttgactt ggaaagttta tcttcttcaa aattttcctt gtatattttc gcctgaatac
    17641 gaggttgaat ggtgtctccc atttcctccg tttttcctga ccaccttact cccatttgtt
    17701 gcaaactatc aataatagcc agattttcag gaaattctgt cttttcctga ttgattaaac
    17761 tttgagatag gcaaatactt gggtcaaaag tcacaaaaac cgctctctta ctgcgagcat
    17821 aggacttaat agactgaatg gcaaaattca agagttcttt atccccataa tccaatatag
    17881 gtcctcttgg gatgtaaaac attttatagc ctagcggaag agttctaatc aaaatactag
    17941 ctgtcgccag taatttttct tccctgtaaa caccaaactt ctcatgttgc caattagact
    18001 taacttcctc ccaagcacta ctttgtaata cattggctaa ttcatgttct ttgacaaact
    18061 gatcatattc taatgtggga atgccaattt gataacggta catttcctac tctctttcct
    18121 ccagtatttt attactattc tactactttc gtttgaaaag tctagtgaaa acatatttta
    18181 ttttagttct actcccccta tgctgaagtt caaactaagt cagtctctct tctaatttga
    18241 aatcaattgg tagggttgtt aaaaaaactt ccaattgttt ttcccagtag taccactcgt
    18301 gagttccagc actatggcta taggtcacat caaaacctag ttttttgaga tttttcactg
    18361 cgagattatt ggcttcgtac aagaaatcct gttcgccaca ccacgcccaa agtttggtct
    18421 ttttatccga ttttttagcc agactttcaa gagaataggg actagttgtc cagtctctaa
    18481 tctctccaaa aacacctctc cagtaggctg gacttcccag attttgactt tcaggagaaa
    18541 agttttgaaa gctgagggca cctgaaaaac tagctgcatg agaaaaacga tttgtcgtaa
    18601 gagccagttt gaagcagccg tagcctccca tagaaagacc agcgataaag gtcttttcac
    18661 gcttgctagt catattaggg aagaagcgtt tcagaacctg tggcaattcc tctgctagag
    18721 ccgtgtagta gtcaaaacca tactgggtgt cggtgtacca accattgctg gtattgggca
    18781 taacaacgat gagattagtt cctcgaagca agcgttctac attggtccgc ttaagccaac
    18841 tattatgatt tccagacatc ccgtgcaaaa ggtacaagac gggaatatct tcacactctg
    18901 gttcttccac tcgattggca tcagggtaga ggacattcac cccccactcc atatccaata
    18961 cttgtgagta atactcgatt ttcattactg ccatgatttt ctccttctat ttttctataa
    19021 gaaaaagccg aaactcgact ttctctctgt ttatttcaac gattattttg cttccatgac
    19081 tactggtaaa atagctggac gacgcttggt ttggtcaaag agatacttgg tcaaattatc
    19141 tcgaaccttc cctttaagat ctgcccagtc aaagtcatct ccttgaagat aatcttctac
    19201 cgtttggtta atcaattctg aactttcacg gagaatatcg cgactcttct tgagataaac
    19261 aaatccgcgc gtatgaacac gagccctagc cacaattttc ttctcacgac ggttgactgt
    19321 aatagccacg atgaaaattc catcctctga caagacctta cggtcacgaa gaacaacatt
    19381 tccaacatca ccaatggcat tcccatcaat taagatatct cctgctgaaa ccgatccagc
    19441 tggaacaaag tctccattct cgtaagccat ggtcgtcccc tttttaggaa tgaagatgcg
    19501 ttctggcaac atcccaactg ccatggcagc cttagcgtga gcatccaact cacgatactc
    19561 cccttggaca gggaagaggt acttaggttg caaaagattg atcatcagct gcaaatcacg
    19621 cacatttccg tgccctgata catgtaaact ttgggtaatc aatttgacaa ccccacctgc
    19681 ctgataaatc atattttcca cacgcgcaac aaaggcttct ttagcaatag acggagccgt
    19741 agcaatatag accaggtccc catccttgat ttctacataa cgatggcgac caatcgacat
    19801 cttacgaagt ccattgatag gttcacccat acgacctgtc tcaagaataa tcaactcatg
    19861 gtcttcaaag cgagacatat ctttaggctt aatcaagaga atttcgttgg ctaaagacaa
    19921 cttcttaaga cgaatcgctg tgcggacgat attttcaata tcaaatcctg tcaagacgat
    19981 acgtcgacct gttttatccg cagcgtcaaa aatctgctga atacgagaaa gattactgga
    20041 aacagctgca acgatgatac gaccttccca gtcagcaata gtttgggtaa tttcatccct
    20101 aacttcactt tcactagcca cctgaatatt gctgtctgca ttggccgaat cactgaggag
    20161 agccagaacg ccgtcacgac caatctctgc caaacgagca aaatcagttg cataagattc
    20221 actagccgtt tggtcaaatt tgaagtcacc tgtataaacg atgcttcctt ccgatgtctt
    20281 caagacaatt cccagactct ctggaacgga gtaagtcgta gggaagaagg aaaccactgt
    20341 cccaccaaaa tcaatctccg tattctcatc aatgacatgg aaatcattaa atttcttaac
    20401 ggcatcattt cctttgacaa agagctttgc caactcaatg gtcaactcag acccaaatac
    20461 aggaacttta gcctctgcca agagataagg tagagcacca atggcatccg catgcccgtg
    20521 ggtcaagaaa accccagcaa tacggtcgct attttcaaaa aggtaatcca tgtttggaat
    20581 caccacatcg acccctaatt gttcattttc aggatatttt aaccctacat tcaaaacaaa
    20641 aatggactct ccaatttcag caatgtacat attttttcca ttctcacgca caccaccaag
    20701 tgttgttaaa ctgatattac tcatttttcc tccaaaatct tagtttatct tgattatagg
    20761 gcaactctac cctcttattc taaaagttct aatactttca gccgaatctt ttcctaccat
    20821 tataccattt ttttgatgat tttcaaaatg aaggtctgtt ttcaaaaaag agttgatttc
    20881 ccaactcttt cctaacttct actctttttc catcaaaaaa tcataaattt cttgcaccgt
    20941 acccagcgcc atcatttctt ggtctttaac ggtttgtttg agattttggt aaatttgact
    21001 ttctcctatc tcccgctttg gcgcctcttt attgactgtc atcacaccat cttttatcgt
    21061 cacaaagcct agttcttcaa atacttgaat catcttgacc agcaagattt gttgaatatt
    21121 aagatatgca gccaaatctt tcagcttgta gcgaatatca aactctggga actggtaaat
    21181 agtcttgtac aatttggcaa actgatctct agtcccataa cctgtcagat aataggcctt
    21241 gtcaatatca tttttgaaat agacagcaga gaaatgctgt tcctgaaaaa tggtcttcag
    21301 ctgagtaata ctctctggaa tgttttttac gacaacagct tcactagccg caagatttgg
    21361 cagttctcca ggaaaatcca agactggaac accttctggc aagactgtat tttttccacg
    21421 aatgttaaaa agttgaacac cttccactcg cgcatccacc atcatcaact ggagggcagt
    21481 ttggccattc cattggttga cagacaattt aaccgctaac tctagattct tggtttgaga
    21541 aaactctgtc gcccatctgc cttgaccaaa ggctaccact tcaaaactcg cctcaccctt
    21601 ggaaattttc agctttagat gggcattacc tgcccccata gtacgagcac tttcgacctg
    21661 aaaattcttg atataaaaaa taggtttctg attatccatt ccaaaaggag ctaaacgttc
    21721 aaaacttttg accgtttcca agctaagtgc ctccaaatcc aactcttcat ctaggtttaa
    21781 cttattcttt ccaccagcat ctgcaccttt ttcacgaaca taatcttcca aaacctgaga
    21841 taaatctgag agttgctcaa cttccagcgt catacccgct gcacctgcat gacctccaaa
    21901 ggcgatgaag aggtctcgat ggggatccag agcttcaaaa atatcgaccg cttccacact
    21961 acgagcactg cccttggcac gaccgtcttc tatattaaga acaatgactg tctgtcccaa
    22021 ttcttccaat aaacgaccag ccacgattcc tagaacccca ggattccagc cttccttggc
    22081 caagacctga accttcttct caggatccac catggtcttg gcttcttcat agatagactg
    22141 aacgatttcc ttgcgctctt cgtttttctg gtgaatcata agggcaatct catgcgcttc
    22201 ctcatcatca aatccagtca acaaatcaat ggcaggattg ggatcatcca agcggcccaa
    22261 ggcattcaaa cgaggagcaa tctggaaacc aaccgtttct tctgttactt cgttggcagc
    22321 aatcccagcc atgtccagca tttcttgcag accaatgcgc tgggtatgac ccaacatttc
    22381 cagaccatat tgaactaaga tacgattttc atccgtcaga ctcaccatat ctgcaatagt
    22441 tccaatagcg accaaatcaa gcaattccac ttgcacttct tctaacaggg cacaagccaa
    22501 cttgaaagca actccacaac cagccaaata tttaaaagga taatccgcat ctggatgttc
    22561 aggatggaca atagcataag catctggcag ggtttcaggc atggaatgat ggtctgtcac
    22621 aatgacatct actcccatag actgagccaa tgcaatagcc tcatgaccag caaccccatt
    22681 gtccaccgtc acaatcaagg aaatcccttc ttgctcgata aagtatttat aaacactagc
    22741 attagggcca tagccatcgg taaaacgatt tggcaggtaa actcggcact cagcaccaag
    22801 ttgttccaaa ctttccttca caatagaagc cgaagtcatg ccatccgcat cgtagtctcc
    22861 ataaacgaga atattttccc tttcttcaat agcctgacga atccgctcca ctgccttgtc
    22921 catatcatgg agcagataag catcatgtaa gtcctccaag gaaggttcta aaaacttctt
    22981 cagactttct tggtcctgaa tccctctctc aaacaataac cgagccacct caggacccag
    23041 tccagccttc ttggctatct ttgtaaaatc cgcatcttct acctgcaggg caaactgcca
    23101 ttcataagta ggtgttatca aaaagacatc cactctttct aagaattcta ttgcttcatt
    23161 ataacatgat ttagacgttt tctctatcca gattgctttt ttataacatt ttatagtata
    23221 ttgaaactag aatagtacac ctctacttct aaaatattgt tagaaatcga tttgactgtc
    23281 ccgatcgatt tgtcctgttc ttatttcact atagtgaatt ttttcagata tggtttgaca
    23341 agaacattct tttattgtag aatcgtgtta taaaatctga cataaatgag ttctctcatg
    23401 gctttagtag aatttaaaaa cgtcgaaaaa tattacggag actaccacgc actccgcaac
    23461 atcaatctcc gttttgaaaa aggacaagtt gttgtcctgc ttggaccttc tggctctggg
    23521 aagtccactc ttatccgtac gatcaatggt ttagaggctg ttgacaaagg aagtctccta
    23581 gtcaatgggc accaagttgc tggtgccagc cagaaagatt tggtacctct tcgcaaggaa
    23641 gtcggcatgg tttttcaaca ttttaacctt tatccacaca aaacagtgtt agaaaacgtg
    23701 acacttgcac ccattaaagt tctaggaatt gataaaaaag aagctgaaaa aaccgcccaa
    23761 aaatatctgg aatttgtaaa tatgtgggac aagaaagatt cctatcccgc catgctatct
    23821 ggtggacaaa aacagcggat cgccatcgct cgtggtcttg ctatgcatcc ggaactcctc
    23881 ctctttgatg aaccaacatc tgctcttgat cctgagacta tcggagatgt tctagcagtt
    23941 atgcagaaac tggcgcgtga tgggatgaac atgatcatcg ttacccacga aatgggcttt
    24001 gctcgagagg ttgcggaccg cattatcttt atggccgacg gagaagtttt agtagatacg
    24061 acagatgtcg ataacttttt tgacaatcca agcgaacctc gtgcccaaca attcctcagc
    24121 aaaattatca accacgaaag tgacaaagtc aaataaggag gcgcctatga aaaaaaaatt
    24181 ctttttatca gcattattga ttagcctttt cggccttgtt gctgccaaac cagtccaggc
    24241 taatactagt atcgcagaca ttcaaaaaag aggcgaactg gttgtcggtg tcaaacaaga
    24301 cgttcccaat tttggttaca aagatcccaa gaccggtact tattctggta tcgaaaccga
    24361 cttggccaaa atggtagctg atgaactcaa ggtcaagatt cactatgtgc cggttacagc
    24421 acaaacccgc ggcccccttc tagacaatga acaggtcgat atggatatcg cgacctttac
    24481 catcacggac gaacgcaaaa aactctacaa ctttaccagt ccctactaca cagacgcttc
    24541 tggatttttg gtcaataaat ctgccaaaat caaaaagatt gaggacctaa acggcaaaac
    24601 catcggagtc gcccaaggtt ctatcaccca acgcctgatt actgaactgg gtaaaaagaa
    24661 aggtctgaag tttaaattcg tcgaacttgg ttcctaccca gaattgatta cttcccttca
    24721 cgctcatcgt atcgatgcct tttccgttga ccgctctatt ctatctggct acactagtaa
    24781 acgcacagaa ctactagatg atagtttcaa gccatctgac tacggtattg ttaccaagaa
    24841 atcaaataca gagctcaacg actatcttga taacttggtt actaaatgga gcaaggatgg
    24901 tagtttgcag aaactttatg accgttacaa gctcaaacca tctagtcata ccgcagatta
    24961 aggaggatac cctatgacag atttatcatc ttggacagcc tattttcagg attttggaca
    25021 atttttcaat ggtttcctct ttactcttgc cctagcgatt ggatccttta tcctcgccat
    25081 ggtcttagga atcttctttg gtgccatgtc aaccagtaaa cgtccaattt tacgcatttt
    25141 agctcgcatc ttcgtggaat tttaccaaaa cactcccctc ttggtgcagt ttgttattgt
    25201 tttttatggc ctacctctta tcagtgacca catcatcatg attccaattt attggacagc
    25261 cgttctctgc gtgggactct atcacggcgc ttatatcgct gaggttattc gttcagggat
    25321 tcagtctatt cctagtggtc agatggaggc cgccttgtcg caaggtttta cctatatcag
    25381 tgccatgcgc ttgattatct tgcctcaggc cttccgcatc attctccctc cattgaccaa
    25441 ccaaattgtt aacctcatca agaacacatc tactgtagct atcatctctg gagtagactt
    25501 gatgtttgtg actaagtctt ggtcggctct caacggaaac tatatcccag cctttttagg
    25561 tgctgctctt ctctactttg ccctatgctt ccctgttgcc cagtttggtc gcaagatgga
    25621 gcaagccaat aaaaaagcct attcacttta ggaggttact atggaatcta ttttagaaat
    25681 tttaacccca gataacctag tctttatctt taaaggattt ggcttgaccc tctatatttc
    25741 tctgattgcc atcatcctct ctactatcat cggtaccgtg cttgccgtca tgcgaaatgg
    25801 aaaaaatcct atcttacgca ttatttccag tatttatatc gagtttgtgc gcaacgttcc
    25861 caaccttctc tggattttta ctatcttttt ggtgttcaaa atgaaatcca caccagcagg
    25921 tattacagcc tttactctct ttacatcagc agccttggct gagattattc gaggcggtct
    25981 caatgccgta gacaagggac aatacgaagc aggaatgtca caaggcttca cctcagccca
    26041 aatcctctac tacatcattc tcccacaagc catccgcaaa atgctaccag ccatcatttc
    26101 tcagtttgtt accgtgatta aggataccag tctcctctac tctgttatcg ccctacaaga
    26161 actctttgga gccagccaaa ttctcatggg ccgttatttc gaaccagagc aggtcttcag
    26221 tctttacatc ctgattgccc tcatctactt cagctttaac ctagcgattt ctagcctgtc
    26281 tcatatgcta gccaaacgtt ggcaacaagc tgcagaataa tactcttcga aaatctcttc
    26341 aaaccacgtc agcttcacct tgccgtactc aagtacagcc tgcggctagc ttcctagttt
    26401 gctctttgat tttcattgag tataaacagc cactctccag ttcaattgga gagttttttg
    26461 atgagagtag atatttatag acctcaattt gacaccatac attttctatg ataaaatgta
    26521 acaaattcat ttacaacaaa tcgaaatcta aatgaaatgg aattttctat gaaatcagtc
    26581 aaaggactac tctttatcat agctagtttt atcttgactc ttttgacttg gatgaacact
    26641 tctccccaat tcatgattcc aggactagct ttaacaagcc tatctctgac ttttatccta
    26701 gccactcgtc tcccactact agaaagctgg tttcacggtt tggagaaggt ctacaccgtc
    26761 cacaaattca cagcctttct ctcaatcatc ctactaatct ttcataactt tagtatgggc
    26821 ggtttgtggg gctctcgctt agctgctcag tttggcaatc ttgccatcta tatctttgcc
    26881 agcatcatcc ttgtcgccta tttaggcaaa tacatccaat acgaagcttg gcgatggatt
    26941 caccgcctgg tttacctagc ctatatttta ggactctttc acatctacat gataatgggc
    27001 aatcgtctcc ttacatttaa tcttctaagt tttcttgttg gtagctatgc ccttttaggc
    27061 ttactagctg gtttttatat catttttcta tatcaaaaga tttccttccc ctatctaggg
    27121 aaaattaccc atctcaaacg cttaaatcac gatactagag aaattcaaat ccatcttagc
    27181 agacctttca actatcaatc aggacaattt gcctttctaa agattttcca agaaggcttt
    27241 gaaagtgctc cgcatccctt ttctatctca ggaggtcatg gtcaaactct ttactttact
    27301 gttaaaaatt caggcgacca taccaagaat atctatgata atcttcaagc cggcagcaaa
    27361 gtaaccctag acagagctta cggacacatg atcatagaag aaggacgaga aaatcaggtt
    27421 tggattgctg gaggtattgg gatcaccccc ttcatctctt acatccgtga acatcctatt
    27481 ttagataaac aggttcactt ctactatagc ttccgtggag atgaaaatgc agtctaccta
    27541 gatttactcc gtaactatgc tcagaaaaat cctaattttg aactccatct aatcgacagt
    27601 acgaaagacg gctatcttaa ttttgaacaa aaaaagtgcc cgaacatgca accgtctata
    27661 tgtgtggtcc tatttctatg atgaaggcac ttgccaaaca gattaagaaa caaaatccaa
    27721 aaacagagct tatttacgaa ggattcaagt tcaaataagt aatcatactc tcctgggatt
    27781 tcccaggaga gttttttata gccaaatgaa ataagacctg aacgatggaa ttttggcatt
    27841 caaatcaatt gataagaata ttttatagtg gagtgaaata ggatacgaac aaattgatta
    27901 ggaaaatcaa atgaatttat agaaatcttt tagcagttat gttgtcctat tctagtttcg
    27961 aaacgctata gaagcagcat tgtgctagtc tagattcagt ttactatact aaaacgagta
    28021 gcttgaaatc aaaaaaccca ccctcacagg caggttttat ctgtattatt cagctagatt
    28081 atgctttacc ttctgaaccg aatacgtcga tacgttcttc aaccgatgct tggatagctt
    28141 ttacaccgtc agccaagaat ttacgtgggt cgaagagttt tttcttgtcg tattctgctt
    28201 cgtttgcttc gtagtcacga gcaaatttac gagttgcgtt agcgaatgcg atttggcatt
    28261 ctgtgttaac gttaactttg gcaacaccaa gtttgatagc tgcttggatt tgctcatcag
    28321 gaatacctga tccaccgtgc aatacgattg ggaatcctgg aagagcttct gtcaattttt
    28381 gcaagtggtc aaggtcaaga ccttcccagt ttactgggta agggccgtgg atgttaccga
    28441 taccagctgc caagaagtcg ataccagttt caaccattgc tttagcgtct tcgattggag
    28501 ccaattcacc tttaccgatg attccgtctt cttcaccacc gatagtacca acttcagctt
    28561 ctactgagat acctttagcg tgtgcttttt caacaacttc tttagccaat ttaaggtttt
    28621 cttcaactgg aaggtgtgaa ccgtcaaaca tgattgaagt ataaccaact tcgatacact
    28681 caagtgcatc ttcgtagtga ccgtggtcaa ggtggatagc tactggtaca gtgataccca
    28741 ttgattcaac aaggttagcg atcaagttgc gagcaacttt gtaaccaccc atgtatttag
    28801 cagcacccat tgaagtttgg atcaaaactg gagctttttt agcttctgct gcgcgcaaga
    28861 tagcttgagt ccactcaagg ttgtttgtgt taaatccacc aactgcataa ccgttgtcac
    28921 gggctgcttg gacaaatttt tctgctgaaa cgattgccat tttatcaggc ctcctgtata
    28981 tttttatggg tcatcccatt tacattgttc attttatcac tttttgccaa aaaaatctag
    29041 tttttcccgc agtttcgatt gattttcttc taactccatc tatgtaaacc ctttctctcc
    29101 ctagtcttgg acgacttttg gaaaatctat aaagaaggtt aaacgattct cctccatctc
    29161 gaaacgataa gctaattttt catgttctaa tagactctta accacaaaga gccccatacc
    29221 agaccccttg accttgcgac tggcattgtc agaaaaagac tgggctagtt tttcttgttc
    29281 ctctgagcta cagctatttt cgataaaaag ttctccttct ctttctccaa ttcgaactaa
    29341 gccacctgga acagagtgct taatggcatt gctgatgaga ttagaaagaa tcaacttcat
    29401 aactgatggg tttagataag cctgctgatg ggtcaaacta ttgtctatct ggagctctct
    29461 ttccttggct agcaaggcat aatctttgac cagattttgc gtcatctgga ggaggtcaat
    29521 tgtttcccta tcatctcgca attcctgcac agaagagagg gaaagtatct gcagaacatg
    29581 gtgattgagt tcatccacaa tccccaaggc aactcccaga tactggtctc tattcttata
    29641 acgaccgata ttctctctca tattttcgat taggattttc aaactagcca gcggtgtttt
    29701 caattcatga gaagctcctc gtaggaattc gaccttcatc ttctccagct ggagaatggc
    29761 ttcattcttt tcatgcaagt ccgcaataac agtcaagaga tgctggtaga ggctattgat
    29821 ttgttccttg agattgccta tctcatcctt agaatccacg cgcaatcgca cttgggaatc
    29881 caggtccatc atccgacggg tcacccgctt gatttccaaa atcggtgcaa caatagtccg
    29941 agcgtagatg taggccacca agagggaaat cagaaaggag gccagcaagg tatagggaag
    30001 aaattggaga ctgatttgct ccgcttcctt ttgtaaatcc atggaagcta gaaactggag
    30061 aatcatagta ccaccgtctt gcgttttcac ctcgcgctcc tcaataaaga gagaggttgt
    30121 atggcggtct gtgtccagag gaagactgtc cttgacttct aacttgtcct cggtcatctc
    30181 acctttgacg gtccccttga tatcactagt ctgggaatac aagtctaaca cttgctcgat
    30241 actctgccta tctttccctt ctagggactg ggcaatggct gttgcctttt gaccaatggt
    30301 ttcctgacga tgactcagat aagtcgaagg aaaaagaaaa taaatagcta aatgaaggca
    30361 gataaccaga acactaaata tcgagaaggt atagataaat atctttgtaa ataaacctgt
    30421 tcgtttcatt ttcgctccaa tttataacca acattgcgca cagtgaggat acaatccaag
    30481 tctagctttt tccgcaattc cttgatataa acatcaataa cacggtcaaa gggaacctca
    30541 tctgtcgctt tccagacggc atcgataatc tgagaccgag tcaaggcccg gccttcattt
    30601 ttcactagat agtccagaat ttccaactct ttggcattga taggcacttc ttgacctgcg
    30661 aggcttgcac tgtagctttc aaagtccacc ttggtatcct tgtaagaaaa gattcgtcct
    30721 gtatcgtagt agcgcttgaa aatcgcgtcc accctcactt ttaagaggga gagggagaaa
    30781 ggtttttcca gatagccatc tgccaaagag gcaaaggcac tcatcttgta ttcctcatcc
    30841 tgaaaagctg tcaacatcaa gacaggaacc tgactggttt tacgaatctc agctaggact
    30901 tctaagccgt taagcttggg catctggata tccagtaaaa ccagggccac ctcatagcta
    30961 gaaaattgct ccagagcttc ctgaccgtcc gctgcctcaa tagtttcata gccacaatcc
    31021 gtcaaataat cactgacccc ctcacggatc atctcttcat cttctacaat taaaattttc
    31081 atactttaac tgctctctat tttttatttt tcttagaata aatacctact ctattttcta
    31141 ttatagtctc ttgctggcct tttgtatgta agcaactgac cactagataa aacgttgtga
    31201 aattcctttc tcataaattc cataacttta gtatattata tttaagcact aaagtacaaa
    31261 gaaagcaact gaaagcaatg attttcacca ctgctttcag atttattttg aattgttaaa
    31321 tagctattcc tatccactat tcttgaatag aaacacaaga tgcaatcttt attccagact
    31381 catttttttc aaatttattc accatccagc aagagctctt ttggttgttt tctaaggaga
    31441 ttgcttgaag caagcgccat aacgagaacc actagaacca aggcaaggac aaaaatgatg
    31501 ataaagtctg atgtctgaat ggaaatgtct aggctcgaca aggtcttgct aaagccatct
    31561 acttctgcac cgccaccaag gttagaggct tgagccgcct tactagcctg tttggcaaca
    31621 cctgaagtca cattggcaag gacagtgttt ccaattgcac gggcagtgta attagctagg
    31681 aagtaagcag aaactagagc agggatagca atcaagatag attcggtgat gaattgaccc
    31741 aagatacttg cctgcttgag accaatagag aggaggattc ccacttcctt gcgacgggca
    31801 ttgatccaaa gactgagcaa gagggcaagg agaaggactg agaagctcaa gctaccccag
    31861 aagaggaggt tggccatctt gtacatacca gagatagatt gctcaagagc tgggtagtta
    31921 gaggagctct tgacgagtgt gtagctcttc cagttgatac cactgatgcc attcaactct
    31981 ttcataacat catccaagtt cttgtctgct gttacaaaga aggttgcgtc cccataaatg
    32041 gctgtgtctt ctgtgtatcc ataaagtttt gcagcagtgt gaatgtctgt aatagctgtg
    32101 ttttcgtaaa gttcttgtga gtaggttact gctgacttat tatgaccatc aaagagtccc
    32161 ttgattgtca cttcaactgt ttccttggct cctttttcat tatctgcatc gtagatatta
    32221 gagtccagtt taaccttgtc ccctactttc cagccgtgtt tggctgccaa gtccttgtgc
    32281 aagaggattt tatccttgtc gtcgttggtt aagtgctctc cttcgactag tttataagaa
    32341 ccagagacaa acttgtcttc tttagaggag tcattgacac ctgtaatcat caagctactt
    32401 ccaaaacgtt tggcacgatc agcagtgaga ttcttcttgg tttctggcgt ttcaatcagg
    32461 tcatatccag tcaaatctcc gatagcgttg atacgtttga cataagactc aatggccttg
    32521 ttttcggtga tttttttgat gtcttcaccc ttgatattcc cagcaccacg aggcgttcct
    32581 tggttgacgc gacgattgat ttgcatggag aagctattgg tgatattttt aaaggtctcc
    32641 tgagaagcct tggcagtagc tcccttgatt gacaagccga ccaaactcaa gctcgccata
    32701 aggagaataa tcaggaagat gacaatcgat ttgaaaaact tccttgtaac ataggcaaat
    32761 gcgttgtgta acatagattc cctttctaga ttttgtttta atcattctat caaaataagc
    32821 tcaaattatt tactagtatt gcgcgtttca gtcagtttct tatcctttaa ttcaagtgta
    32881 atatctgacg cttgtgccac ttctttactg tgagttacga caatcacaca tttacctgtt
    32941 ttctgggcaa gtgatttgag tagttcgaca atatctccag cagttttagg atccagattt
    33001 cctgttggct catcagctag aataactgga gcttctgaga ccaaactgcg agcaatggca
    33061 acacgttgct gttgaccacc tgataactgg agaacattcc gcttaatctg gctttcatcc
    33121 aaaccaagct caagaagtgt attcttgctt gcctttttgt tgaccaattg gatattttcc
    33181 agcggagaaa gataatctat caagttataa ttttgaaaga ccagggaaat atggtgcatg
    33241 cgatggtaag aatagccctt cttacgaata tcctctcctt gaaaaaggat agaaccttca
    33301 acaggactat ctagaccagc aagtagggac aagagtgtgg attttcctgc tcctgactcc
    33361 ccaataatac tgtaaaattt tccgggttca aaattataat tgatctgata taggactgct
    33421 tcagcagtat tcttataacg gtaggtaaca tcttgtaatt gtaataaagt catgatttct
    33481 ccttcttaac taatagatga taaaatttct ttcggtgatt ttctaaataa gaataggaaa
    33541 caaagggcta cagataagca actaagcaga actagaaaaa cataggattc tgcaaaagat
    33601 aagatgctag ttgataaact gcttgctttg gctagtgtat cttgtaagct tacctgatct
    33661 ccacttgcta gtagagtttg gagtaggtaa gttgtgattc cgtttcctgc aacaaatgct
    33721 ggaagcaaag ctccaagaga taccaaaact acctctaaac agaattgtag gaagatcgag
    33781 ctcttgcctt ttccaagtgc aagtaaaatc cccacttcat agacccgttc tctcaaccag
    33841 agagacaaaa ccagaattaa ggctccagct cctgctatca acatcccata aaggaagatg
    33901 gtcaggaagg tttggaaagt tgcaactgag tctttgattt gttcaaaagc cttgttttcc
    33961 ttttcgactt ggtagccttg attttccaag gccaagtttt ctacctgctt catgagtccg
    34021 tccatttcct taggattttc tacatagaag cgtgctgcac tgacttgagc ttcactattg
    34081 cccaaaaggg tttggctact ttcataatct gtaaagactt gattttcact gaagtcagaa
    34141 gacaagcctg tgaatttctc ttgtttttta ccagaaaaga tgccgataat ctcaaactct
    34201 actgtttgtc cttttccaga ttcagactga ccagcatcca agccaatctt gtcatgaagt
    34261 gaaagaccgt tcttcttagc caattcttcg tggataagga ttttcttgga atcccctttt
    34321 tgaaggtgtc gcccttcttt tagattgaaa gccgaactgg taaaggttac atccttggat
    34381 gaatcctcaa gagccgttaa gctaaccaag ttattgtctg cagctgataa atcatcacgc
    34441 tccacgctct gctcgccagt cactgcttcc ttgtctttta gttttgcgac cgtctcaagt
    34501 tcaggagaga cattttccag ccccttaatc ttgcttacag atgctaggtc tgacaacttg
    34561 aatgtctgac cattctctat cttcttaata gaaaaagatg tattgagtga tttataaaga
    34621 ttgctttcta ctgttttgtt ggacttcatc agagtcaaac aggctgaaat tccggccaat
    34681 aagaccaata aaatcagaaa taaaataaaa cttctcagtc gctttctgct gacataagcc
    34741 caagatcttt ggattggatt catttgtcac ctccatattt gtaagactat tataaaaccc
    34801 aaatatgaaa tgtttatgaa atacgaaaaa aaaaa
//
LOCUS       DAVKMO010000017        34424 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVKMO010000017 DAVKMO010000000
VERSION     DAVKMO010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34424
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.017"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            530..982
                     /locus_tag="VW361_000954"
     CDS             530..982
                     /locus_tag="VW361_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9744017.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1001..2338
                     /locus_tag="VW361_000955"
     CDS             1001..2338
                     /locus_tag="VW361_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU9744018.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSIQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2417..3301
                     /locus_tag="VW361_000956"
     CDS             2417..3301
                     /locus_tag="VW361_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9744019.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTIFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3301..4134
                     /locus_tag="VW361_000957"
     CDS             3301..4134
                     /locus_tag="VW361_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9744020.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4152..6245
                     /gene="nanB"
                     /locus_tag="VW361_000958"
     CDS             4152..6245
                     /gene="nanB"
                     /locus_tag="VW361_000958"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU9744021.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFENATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6258..7361
                     /locus_tag="VW361_000959"
     CDS             6258..7361
                     /locus_tag="VW361_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9744022.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7535..8233
                     /locus_tag="VW361_000960"
     CDS             7535..8233
                     /locus_tag="VW361_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU9744023.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8252..9769
                     /locus_tag="VW361_000961"
     CDS             8252..9769
                     /locus_tag="VW361_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9744024.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9894..11222
                     /locus_tag="VW361_000962"
     CDS             9894..11222
                     /locus_tag="VW361_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9744025.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11474..12340
                     /locus_tag="VW361_000963"
     CDS             11474..12340
                     /locus_tag="VW361_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9744026.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12356..13195
                     /locus_tag="VW361_000964"
     CDS             12356..13195
                     /locus_tag="VW361_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9744027.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13468..13920
                     /locus_tag="VW361_000965"
     CDS             13468..13920
                     /locus_tag="VW361_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9744028.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            14017..14361
                     /locus_tag="VW361_000966"
     CDS             14017..14361
                     /locus_tag="VW361_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744029.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIIRGIVTGLIGGHIKLGAY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGRILQIAVNVADVYGNFAYNIAAAWDA
                     HDKIPNNGRINF"
     gene            14646..15290
                     /locus_tag="VW361_000967"
     CDS             14646..15290
                     /locus_tag="VW361_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9744030.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15459..16376
                     /locus_tag="VW361_000968"
     CDS             15459..16376
                     /locus_tag="VW361_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU9744031.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16394..17278
                     /locus_tag="VW361_000969"
     CDS             16394..17278
                     /locus_tag="VW361_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9744032.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASMTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17294..18145)
                     /locus_tag="VW361_000970"
     CDS             complement(17294..18145)
                     /locus_tag="VW361_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU9744033.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18345..20402
                     /gene="pbp2b"
                     /locus_tag="VW361_000971"
     CDS             18345..20402
                     /gene="pbp2b"
                     /locus_tag="VW361_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU9744034.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKIVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20413..21009
                     /gene="recR"
                     /locus_tag="VW361_000972"
     CDS             20413..21009
                     /gene="recR"
                     /locus_tag="VW361_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU9744035.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21185..22228
                     /locus_tag="VW361_000973"
     CDS             21185..22228
                     /locus_tag="VW361_000973"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU9744036.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISRSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKVTMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22312..23685
                     /locus_tag="VW361_000974"
     CDS             22312..23685
                     /locus_tag="VW361_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU9744037.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTTYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLVP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLSANDQILLKGSNSMNLAMLVE
                     SLENETK"
     gene            23672..24283
                     /locus_tag="VW361_000975"
     CDS             23672..24283
                     /locus_tag="VW361_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9744038.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIEILWQVYQGQMEQYLD"
     gene            24374..25078
                     /locus_tag="VW361_000976"
     CDS             24374..25078
                     /locus_tag="VW361_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU9744039.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTIYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGIFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25297..26670
                     /gene="ftsA"
                     /locus_tag="VW361_000977"
     CDS             25297..26670
                     /gene="ftsA"
                     /locus_tag="VW361_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU9744040.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRTGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26687..27946
                     /gene="ftsZ"
                     /locus_tag="VW361_000978"
     CDS             26687..27946
                     /gene="ftsZ"
                     /locus_tag="VW361_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU9744041.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETAELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27951..28622
                     /locus_tag="VW361_000979"
     CDS             27951..28622
                     /locus_tag="VW361_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU9744042.1"
                     /translation="MNVKENTELVFREVAEASLSANRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELMEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28632..29171
                     /locus_tag="VW361_000980"
     CDS             28632..29171
                     /locus_tag="VW361_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU9744043.1"
                     /translation="MSLKDRFDRFIDYFTENEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29171..29434
                     /locus_tag="VW361_000981"
     CDS             29171..29434
                     /locus_tag="VW361_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU9744044.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSIWVAIVLVRFLGENLVRFLAMIG"
     gene            29431..30216
                     /locus_tag="VW361_000982"
     CDS             29431..30216
                     /locus_tag="VW361_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU9744045.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30225..30959
                     /gene="divIVA"
                     /locus_tag="VW361_000983"
     CDS             30225..30959
                     /gene="divIVA"
                     /locus_tag="VW361_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001123193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU9744046.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVHDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DLLRPTATYLQTSDEAFKEVVSKVLGEPIPAPIEEEPIDMTRQFSQAEMAELQARIEV
                     ADKELAEFEAQIKQEVEAPTCSESSG"
     gene            31359..34151
                     /locus_tag="VW361_000984"
     CDS             31359..34151
                     /locus_tag="VW361_000984"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU9744047.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEAQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10594 a         6090 c         7480 g        10260 t
ORIGIN      
        1 agtatttctc tcttaaaagt ttttggtgaa acgagatgta gaaaggagat ttagccaaag
       61 agtctattag tgctagaata atagattaga attattttag aaaaacgaag tgagcagctt
      121 ataaattcaa gtccccaaat agattcatac tagtatcttt tgcaaaaaat aaagggcgac
      181 ttccttcatg aatatcaatt tcatctataa ggaaggtagc taattgaact aacttattta
      241 ttctgtttgt cgctagaaaa atcagacctc cttgtgaaga ttgaggagat acttaatgaa
      301 aatcaaagaa gaaactagca agctagtagc agattgccca aaacaccgct ttgaggttgt
      361 agataagact gacctatata atccaaggtg aagcgactgt ggtttgaaga gattttcaaa
      421 gagtataggc tagagagtag tgtttttatg tccttctagt agaaaatgct agacagaaga
      481 atggggaact tggataggaa aaatagattg agaaaggagg ttagaagaga tgattattac
      541 aaaaattagc cgtttaggaa cttatgtggg agtaaatcca cattttgcaa cattaataga
      601 ttttctagaa aaaacaggac tagaaaattt aacagaaggt tcgattgcta tcgatggtaa
      661 tcgattgttt gggaattgct ttacttatct agcagatggt caagcagggg ctttctttga
      721 aacacaccaa aaatatttgg atattcattt agttttggaa aacgaagaag ccatggctgt
      781 tacatcgccg gaaaatgtaa gcgttaccca agaatatgat gaagagaaag atattgaatt
      841 atacacaggg aaagtggaac agttggttca tttgagagct ggtgaatgcc tcatcacttt
      901 tccagaagat ttacatcaac ccaaggttcg tataaatgat gaacctgtga aaaaagttgt
      961 ctttaaagtt gcgatttctt aatgtagaaa gagaagaacg atgaaaaaaa tgagaaagtt
     1021 tttatgtcta gctggaattg cgctagcggc tgttgccttg gtagcttgtt caggaaaaaa
     1081 agaagctaca actagtactg aaccaccaac agaattatct ggtgagatta caatgtggca
     1141 ctcctttact caaggacccc gtttagaaag tattcaaaaa tcagcagatg ctttcatgca
     1201 aaagcatcca aaaacgaaaa tcaagattga aacattttct tggaatgact tctatactaa
     1261 atggactaca ggtttagcaa atggaaatgt gccagatatc agtacagctc ttcctaacca
     1321 agtaatggaa atggtcaact cagatgcttt ggtgccgcta aatgattcta tcaagcgtat
     1381 tggacaagat aaatttaacg aaactgcctt aaatgaggca aaaatcggag atgattacta
     1441 ctctgttcct ctttattcac atgcacaagt catgtgggtt agaacagatt tgttaaaaga
     1501 acataatatt gaggttccta aaacttggga tcaactctat gaagcttcta aaaaattgaa
     1561 agaagctgga gtttatggct tgtctgttcc gtttggaaca aatgacttaa tggcaacacg
     1621 tttcttgaac ttctacgtac gtagtggtgg aggaagcctc ttaacaaaag atcttaaagc
     1681 agacttgaca agccaacttg ctcaagatgg tattaaatac tgggttaaat tgtataaaga
     1741 aatctcacct caagattctt tgaattttaa tgtccttcaa caagctacct tgttctatca
     1801 aggaaaaaca gcatttgact ttaactctgg cttccatatc ggaggaatta atgccaacag
     1861 tcctcaattg attgattcga ttgatgctta tcctattcca aaaatcaaag agtctgataa
     1921 agaccaagga attgaaacct caaacattcc aatggttgtt tggaaaaatt caaaacatcc
     1981 agaagttgct aaagcattct tagaagcact ttataatgaa gaagactacg ttaaattcct
     2041 tgattcaact ccagtaggta tgttgccaac tattaagggg attagcgatt ctgcagccta
     2101 taaagaaaat gaaactcgta agaagtttaa acatgctgaa gaagtaatta ctgaagctgt
     2161 taaaaaaggt actgctattg gttatgaaaa tggaccaagt atacaagctg gtatgttgac
     2221 taaccaacac attattgaac aaatgttcca agatatcatt acaaatggaa cagatcctat
     2281 gaaagcagca aaagaagcag aaaaacaatt aaacgattta tttgaggctg ttcagtagat
     2341 gtaaaagact agaaaatagg tgggctagtg agctgaaaag ctctagccca attttgtaaa
     2401 agaagggaga aggagaatgg ttaaagaacg taatttaact cgctggatat ttgttttgcc
     2461 agctatgatt atcgtaggat tactctttgt ttatccgttt ttctcgagta ttttttatag
     2521 ctttaccaat aagcatttga ttatgcctaa ttataaattt gttggtttgg ctaactataa
     2581 agctgtgcta tcagatccca acttctttaa tgcgttcttt aattcaatta agtggaccat
     2641 tttctcatta gttggtcaag ttttagtagg gtttgtattg gctttagctc ttcacagagt
     2701 acgccacttc aagaaattat ataggacctt attgattgtt ccttgggcat ttcctaccat
     2761 cgttattgcc ttctcttggc agtggattct aaacggggtt tatggctact tacctaatct
     2821 aatcgtaaaa ttaggtttaa tggaacatac acctgcattt ttgacagata gtacatgggc
     2881 attcctatgt ttggtgttta tcaacatttg gtttggagca ccaatgatta tggttaatgt
     2941 gctttcagct ttgcaaacag taccagaaga acaatttgag gctgctaaga tagatggtgc
     3001 ttcaagttgg caggtgttca agtttatcgt ctttccacat attaaagtgg ttgtaggact
     3061 tctagttgtt ttgagaactg tatggatctt taataacttt gacattatct acctcattac
     3121 tggtggtgga ccagccaatg ctacaacgac gcttccaatt tttgcttaca acctgggctg
     3181 gggaactaaa ttgttgggtc gtgcttcagc agttacagta ttgctcttta tcttcttggt
     3241 ggcgatttgc tttatctact ttgctatcat cagtaagtgg gaaaaggagg gtagaaaata
     3301 atgaagaaga aatccagtat ttatttagat attctctcac atgtactttt agttggtgcg
     3361 accatcgttg cagttttccc attggtatgg attatcatat cttctgtcaa agggaaaggg
     3421 gaattaactc agtatccaac acgattttgg cctgaacagt ttacattaga ttatttcact
     3481 catgttatca acgatttgca cttcattgat aacattcgaa acagtttaat cattgccttg
     3541 gctacaaccc ttattgcgat tattatttct gctatggcag cctatggtat tgttcgattc
     3601 tttcctaaat tgggagcaat catgtcgaga ctactcgtca ttacctacat tttcccacca
     3661 attttgttag caattcccta ttcaattgcc attgctaaag ttgggttaac aaatagttta
     3721 tttggcttga tgatggttta tctatctttt agtgttccat atgcagtttg gctcttagtt
     3781 ggatttttcc aaacagttcc aattggaatt gaagaagcgg ctagaattga tggtgcaaat
     3841 aaatttgtta cgttttataa agttgtgcta ccgattgtag caccaggtat tgtagcaaca
     3901 gctatttata catttatcaa tgcttggaat gaattcctgt atgccttgat tttgattaac
     3961 aatacaggaa agatgacagt agcagtagcc cttcgttcac ttaatggttc agaaatacta
     4021 gactggggag atatgatggc agcgtctgtt attgtagttc ttccatcaat tattttcttc
     4081 tctatcatcc aaaataagat tgcaagtgga ttatcagaag gatctgtgaa gtagacgaaa
     4141 gaaggaaaaa aatgaataaa agaggtcttt attcaaaact aggaatttct gttgtaggca
     4201 ttagtctttt aatgggagtc cccactttga ttcatgcgaa tgaattaaac tatggtcaac
     4261 tgtccatatc tcctattttt caaggaggct catatcaact gaacaataag agtatagata
     4321 tcagcccttt gttattagat aaattgtctg gagagagtca gacagtagta atgaaattta
     4381 aagcagataa accaaactct cttcaagctt tgtttggcct atctaatagt aaagcaggct
     4441 ttaaaaataa ttacttttca attttcatga gagattctgg tgagataggt gtagaaataa
     4501 gagacgccca aaagggaata aattatttat tttctagacc agcttcatta tggggaaagc
     4561 ataaaggaca ggcagttgaa aatacactag tatttgtatc tgattctaaa gataaaacat
     4621 acacaatgta tgttaatgga atagaagtgt tctctgaaac agttgataca tttttgccaa
     4681 tttcaaatat aaatggtata gataaggcaa cactaggagc tgttaatcgt gaaggtaagg
     4741 aacattacct cgcaaaagga agtattgatg aaatcagtct atttaacaaa gcaattagtg
     4801 atcaggaagt ttcaaatatt cccttgtcaa atccatttca gttaattttc caatcaggag
     4861 attctactca agctaactat tttagaatac cgacactata tacattaagt agtggaagag
     4921 ttctatcaag tattgatgca cgttatggtg ggactcatga ttctaaaagt aagattaata
     4981 ttgccacttc ttatagtgat gataatggga aaacgtggag tgagccaatt tttgctatga
     5041 agtttaatga ctatgaggag cagttagttt actggccacg agataataaa ttaaagaata
     5101 gtcaaattag tggaagtgct tcattcatag attcatccat tgttgaagat aaaaaatctg
     5161 ggaaaacgat attactagct gatgttatgc ctgcgggtat tggaaataat aatgcaaata
     5221 aagccgactc aggttttaaa gaaataaatg gtcattatta tttaaaacta aagaagaatg
     5281 gagataacga tttccgttat acagttagag aaaatggtgt cgtttatgat gaaacaacta
     5341 ataaacctac aaattatact ataaatgata agtatgaagt tttggaggga ggaaagtctt
     5401 taacagtcga acaatattcg gttgattttg atagtggctc tttaagagaa aaacataatg
     5461 gaaaacaggt ccctatgaat gttttctaca aagattcgtt atttaaagtg actcctacta
     5521 attatatagc aatgacaact agtcagaata gaggagagag ttgggaacaa tttaagttgt
     5581 tgcctccgtt cttaggagaa aaacataatg gaacttactt atgtcccgga caaggtttag
     5641 cattaaaatc aagtaacaga ttgatttttg caacatatac tagtggagaa ctaacctatc
     5701 tcatttctga tgatagtggt caaacatgga agaaatcctc agcttcaatt ccgtttgaaa
     5761 atgcaacagc agaagcacaa atggttgaac tgagagatgg tgtgattaga acattcttta
     5821 gaaccactac aggtaagata gcttatatga ctagtagaga ttctggagaa acatggtcgg
     5881 aagtttcgta tattgatgga atccaacaaa cttcatatgg cacacaagta tctgcaatta
     5941 aatactctca attaattgat ggaaaagaag cagtcatttt gagtacacca aattctagaa
     6001 gtggccgtaa gggaggtcaa ttagttgtcg gtttagtcaa taaagaagat gatagtattg
     6061 attggaaata ccactatgat attgatttgc cttcgtatgg ttatgcctat tctgcgatta
     6121 cagaattgcc aaatcatcac ataggtgtac tgtttgaaaa atatgattcg tggtcgagaa
     6181 atgaattgca tttaagcaat gtagttcagt atatagattt ggaaattaat gatttaacaa
     6241 aataaaggag aaaaaacatg gttaaatacg gtgttgttgg agcagggtat tttggagctg
     6301 aattggctcg ctacatgcaa aagaatgatg gagcagagat tactcttctc tatgatccag
     6361 ataatgcaga ggcgattgca gaagaattgg gagcaaaagt agcaagttcc ttagatgagt
     6421 tggtttctag cgatgaagta gattgtgtta tcgtcgcaac tccaaataat cttcataagg
     6481 aaccggttat taaggctgca cagcatggta aaaatgtttt ctgtgaaaaa ccaattgcgc
     6541 tttcttatca agattgtcgc gagatggtag atgcgtgtaa agaaaacaat gtaaccttta
     6601 tggcaggaca tattatgaat ttctttaatg gtgttcatca tgcaaaagaa ctcattaatc
     6661 aaggagttat cggagacgtt ctatattgtc atacagctcg taatggttgg gaagaacaac
     6721 aaccgtcagt atcatggaaa aaaattcgtg aaaaatcagg tggtcacttg tatcaccaca
     6781 tccatgaatt ggattgcgtt caattcctta tggggggcat gcctgaaact gtaaccatga
     6841 caggtggaaa tgtggcccat gaaggtgaac atttcggtga tgaagatgat atgatttttg
     6901 tcaatatgga attttctaat aagcgttttg ctttgttaga atggggttca gcttatcgtt
     6961 ggggtgaaca ttatgtctta atccaaggaa gcaaaggtgc catccgctta gacttattca
     7021 actgtaaagg aactcttaag ctagatgggc aagaaagcta tttcttgatt cacgaatcgc
     7081 aagaagaaga tgatgatcgg actcgtatct atcatagtac agagatggat ggagcaattg
     7141 cttatggtaa accaggtaaa cgtactccat tatggctatc atctgtcatt gataaagaaa
     7201 tgcgctatct gcatgagatt atggaaggag ctccagtatc agaagaattt gcaaaacttt
     7261 tgacaggtga agctgcccta gaagcaattg ctactgcaga tgcttgtacc cagtctatgt
     7321 ttgaagatcg caaagtaaaa ttgtcagaaa ttgtaaaata aattttggta ttctcctatt
     7381 tataggtcga cttgctcctc tgaaagtact tttagaggag ctgtttgact ttgctagttt
     7441 ttgaaactga aatctattat actacaaact attgaaagcg ttttaatttt aaggtataat
     7501 aatctcatag aaataaagaa aaggaggaaa gaggatgcca cagattagca aagaagcctt
     7561 gattgagcaa atcaaagatg gaatcatcgt ttcttgtcag gctcttcctc atgaaccgct
     7621 ttatacagaa gcgggagggg tgattccctt gctggtcaaa gcggctgagc aaggtggagc
     7681 agtcggtatc cgagcaaaca gtgttcgcga tatcaaggaa attaaggagg tcactaaact
     7741 tccaatcatt gggattatca aacgtgatta tccacctcag gaacccttca tcacggctac
     7801 tatgaaagaa gttgatgaat tggcagaact ggacatcgag gtgattgctc tggattgtac
     7861 caagcgtgaa cgctacgatg gtttggaaat tcaagagttc attcgtcagg ttaaggagaa
     7921 atatcctaat cagcttttga tggctgatac tagtatcttc gaagaagggc tagcagctgt
     7981 agaagcagga attgactttg tcggaacaac cttatcaggc tacacatcct acagtccaaa
     8041 agtagacggt ccagattttg aattgattaa gaaactctgt gatgccggtg tagatgtcat
     8101 tgcagaagga aaaattcata caccagaaca agccaaacaa atccttgaat atggagtgcg
     8161 aggcatcgtt gttggtggcg ccattactag accaaaagag attacagaac gcttcgttgc
     8221 tagtcttaaa taagatgtga gggggagttt tatgtttaaa gttttacaaa aagttggaaa
     8281 agcttttatg ttacctatag ctatacttcc tgcagcaggt ctacttttgg ggattggtgg
     8341 tgcactttca aacccaacca cgatagcaac ttatccaata ctagacaata gtatttttca
     8401 atcaatattc caagtaatga gctctgcagg agaggttgta ttcagtaatt tgtcactact
     8461 tctctgtgtg ggattatgta ttggcttagc gaaacgagat aaaggaaccg ctgcgttagc
     8521 aggagtaact ggttacttag ttatgactgc aacgatcaaa gctttagtaa aactttttat
     8581 ggcagaagga tctgcaattg atactggagt tattggagca ttagttgtcg gaatagttgc
     8641 cgtatatttg cacaaccgat ataacaatat tcaattacct tccgctttag gattctttgg
     8701 aggttcacgc ttcgttccta ttgttacatc gttctcttct atcttgattg gctttgtctt
     8761 ctttgttatt tggccacctt tccaacaact tcttgtttct acaggtggat atatttctca
     8821 ggcgggtcca attggaactt ttctatatgg atttttaatg agactttctg gagcagtagg
     8881 cttacatcat ataatttacc ctatgttttg gtatactgaa cttggtggtg ttgaaactgt
     8941 tgcaggacaa acagtggttg gagctcaaaa aatatttttt gctcaattag ccgatctggc
     9001 ccattctgga ttatttacag aaggaacaag gttttttgca ggtcgtttct caacaatgat
     9061 gttcggttta ccggctgcct gtttagcgat gtaccatagt gttcctaaaa atcgtcgtaa
     9121 aaaatacgcg ggtttgtttt ttggagttgc tttaacatct tttattaccg gtattacaga
     9181 accaattgaa tttatgtttc tattcgtcag tccggttcta tatgttgttc acgcattcct
     9241 tgatggtgtt agcttcttta ttgcagacgt cttaaatatt tcaataggaa acacattttc
     9301 aggaggtgta atcgatttca ctttatttgg aattttgcag gggaacgcta agacgaattg
     9361 ggttcttcag attccatttg gacttatttg gagtgttttg tattatatta tttttagatg
     9421 gttcattact caattcaacg ttctaacgcc aggacgagga gaagaagtag attctaaaga
     9481 aatttctgaa tccgcagatt caacttcaaa tactgcagat tatttaaaac aggatagcct
     9541 acaaattatc agagccttgg gtggatcaaa taatatagaa gatgtagatg cttgtgtgac
     9601 acgtttacgt gtagctgtaa aagaagttaa tcaagttgat aaagcacttt taaaacaaat
     9661 tggtgcagtt gatgtcttag aagtgaaggg tggcattcaa gcaatctatg gagcaaaagc
     9721 aatcttatat aaaaatagta ttaatgaaat tttaggtgta gatgattaag tacttactga
     9781 cttaataaaa aacagaggag agtgatggat gagtaggatg aaatgaaatc gcatacaaga
     9841 aataaagaac tcattatcca agttggatac gcttattaca taggagaata caaatgaaat
     9901 ttagaaaatt agcttgtaca gtacttgcgg gtgctgcggt tcttggtctt gctgcttgtg
     9961 gcaattctgg cggaagtaaa gatgctgcca aatcaggtgg tgacggtgcc aaaacagaaa
    10021 tcacttggtg ggcattccca gtatttaccc aagaaaaaac tggtgacggt gttggaactt
    10081 atgaaaaatc aatcatcgaa gcgtttgaaa aagcaaaccc agatataaaa gtgaaattgg
    10141 aaaccatcga cttcaagtca ggtcctgaaa aaatcacaac agccatcgaa gcaggaacag
    10201 ctccagacgt actctttgat gcaccaggac gtatcatcca atacggtaaa aacggtaaat
    10261 tggctgagtt gaatgacctc ttcacagatg aatttgttaa agatgtcaac aatgaaaaca
    10321 tcgtacaagc aagtaaagct ggagacaagg cttatatgta tccgattagt tctgccccat
    10381 tctacatggc aatgaacaag aaaatgttag aagatgctgg agtagcaaac cttgtaaaag
    10441 aaggttggac aactgatgat tttgaaaaag tattgaaagc acttaaagac aagggttaca
    10501 caccaggttc attgttcagt tctggtcaag ggggagacca aggaacacgt gcctttatct
    10561 ctaaccttta tagcggttct gtaacagatg aaaaagttag caaatataca actgatgatc
    10621 ctaaattcgt caaaggtctt gaaaaagcaa ctagctggat taaagacaat ttgatcaata
    10681 atggttcaca atttgacggt ggggcagata tccaaaactt tgccaacggt caaacatctt
    10741 acacaatcct ttgggcacca gctcaaaatg gtatccaagc taaactttta gaagcaagta
    10801 aggtagaagt ggtagaagta ccattcccat cagacgaagg taagccagct cttgaatatc
    10861 ttgtaaacgg gtttgcagta ttcaacaata aagacgacaa gaaagtcgct gcatctaaga
    10921 aattcatcca gtttatcgca gatgacaaag agtggggacc taaagacgta gttcgtacag
    10981 gtgctttccc agtccgtact tcatttggaa aactttatga agacaaacgc atggaaacaa
    11041 tcagcggctg gactcaatac tactcaccat actacaacac tattgatgga tttgctgaaa
    11101 tgagaacact ttggttccca atgttgcaat ctgtatcaaa tggtgacgaa aaaccagcag
    11161 atgctttgaa agccttcact gaaaaagcga acgaaacaat caaaaaagct atgaaacaat
    11221 agtccttagt tattctataa aaagtagttt tttaaagaac ctaagagtgt ataccccctt
    11281 ttccctctac acagatagtg taagaaaagg gggcttttgt ttaaaatgta agaaactgtc
    11341 acgaaattaa aatgaagttc ttacataagc gaaccataaa aaatttcatt ttgattttaa
    11401 aacagttcaa gaaagtcaaa aaattattct atttgaaaga gaggtgccga ctgtgaaagt
    11461 caataaaatc cgtatgcggg aaacagtgat ttcctatgct ttcctagcac cagtattatt
    11521 cttctttgtc atctttgtgt tggctccgat ggtgatgggc ttcattacaa gtttctttaa
    11581 ctactcaatg actaaatttg agtttgtagg cttggataac tatatccgta tgtttaaaga
    11641 tcctgtcttt acaaaatctc tgattaacac agttattttg gttattggat ctgtaccagt
    11701 tgttgttcta ttctcactct ttgtagcatc tcagacctat catcaaaatg tcattgccag
    11761 atccttctac cgtttcgtct tcttccttcc tgttgtaacg ggtagtgttg ccgtgacagt
    11821 tgtttggaaa tggatttatg acccactatc agggattcta aactttgtcc ttaagtcaag
    11881 ccacatcatc agccaaaaca tttcttggtt gggagataaa aactgggcat tgatggcgat
    11941 tatgattatt ctcttgacca cttcagttgg tcagcccatc atcctttata tcgctgccat
    12001 ggggaatatt gacaattcac tggttgaagc ggcgcgtgtt gatggtgcaa ctgagtttca
    12061 agttttttgg aagattaaat ggccaagcct tcttccaaca actctttata ttgcaatcat
    12121 cacaacaatt aactcattcc agtgtttcgc cttgattcag cttttgacat ctggtggtcc
    12181 aaactactca acaagtacct tgatgtacta cctttacgaa aaagccttcc aattgacaga
    12241 atacggctat gccaacacaa ttggtgtctt cttggcagtc atgattgcta tcgtaagctt
    12301 tgttcaattt aaagtacttg gaaacgacgt agaatactaa agaaaggaga cagctatgca
    12361 atctacagaa aaaaaaccat taacagcctt tactgttatt tcaacaatca ttttgctctt
    12421 gttgactgtg ctgttcatct ttccattcta ctggattttg acaggggcat tcaaatcaca
    12481 acctgataca attgttattc ctcctcagtg gttccctaaa atgccaacca tggaaaactt
    12541 ccaacaactc atggtgcaga accctgcctt gcaatggatg tggaactcag tatttatctc
    12601 attggtaacc atgttcttag tttgtgcaac ctcatctcta gcaggttatg tattggctaa
    12661 aaaacgtttc tatggtcaac gcattctatt tgctatcttt atcgctgcta tggcgcttcc
    12721 aaaacaagtt gtccttgtac cattggtacg tatcgtcaac ttcatgggaa tccacgatac
    12781 tctctgggca gttatcttgc ctttgattgg atggccattc ggtgtcttcc tcatgaaaca
    12841 gttcagtgaa aatatcccta cagagttgct tgaatcagct aaaatcgacg gttgtggtga
    12901 gattcgtacc ttctggagtg tagccttccc gattgtgaaa ccagggtttg cagcccttgc
    12961 aatctttacc ttcatcaata cttggaatga ctacttcatg cagttggtaa tgttgacttc
    13021 acgtaacaat ttgaccatct cacttggggt tgcgaccatg caggctgaaa tggcaaccaa
    13081 ctatggtttg attatggcag gagctgccct tgctgctgtt ccaatcgtca cagtcttcct
    13141 agtcttccaa aaatccttca cacagggtat tactatggga gcggtcaaag gataatactc
    13201 tgcgaaaatc gaatgcaaac tacgtcagct tcaccttgcc atacttaagt attgcctgtg
    13261 gttagcttcc tagtttgttc ttcaattttc attgagtata ggaaaatcaa tctatcaaga
    13321 tacagaagta tattttatag atttagagaa tatagaagtt ataagtgtct acaaaatgga
    13381 gggtatgcag ttactttatg aagttttgtc agacacttat aaacttaaga atggttttag
    13441 ttaactatca gaaacgaagg aaagagtatg atttttgacg atttgaaaaa catcaccttt
    13501 tacaaaggga ttcatcccaa tttagacaag gctatcgact atctctacca acatcgtaaa
    13561 gattcattcg aattaggaaa gtatgagatt gatggagata aagtctttct agttgttcag
    13621 gaaaatgtcc tcaatcaagt tgagaataat caatttgaac accataagaa ctatgcagat
    13681 ttgcatttgc tgatagaagg gcatgaatat tcgagctacg gttcacgtat caaagacgag
    13741 gcagtagcat tcgacgaagc gagtgacatt ggctttgttc attgtcatga acactaccca
    13801 ctcttgttgg gttatcacaa ttttgcgatt ttcttcccag gtgagccaca tcagccaact
    13861 ggttatgcag gcatggaaga aaaggttcgg aaatatctct ttaaaatttt gattgattaa
    13921 aaataggatg aattgttttt ttgtaaagct ttgacaatac tctaccatga aattgatctt
    13981 tgtgaggtag agaaatgaga ataaaatatt taaaaattgg tatcttctaa gcatgctgca
    14041 agagctagtt tcttagatgg acagggaatt acagttgatg agatgtcctg gataattagg
    14101 ggcattgtga ctggattgat tggcggacac ataaaattag gtgcttatgc agctaagtat
    14161 ggtattagta tagcacgatc gatcttaagt agggcagctg caactgcagc agcaagagta
    14221 ggattactga ccaagatttc tggaaggatt ttacaaatag ctgtgaatgt agctgatgta
    14281 tatggtaatt ttgcctacaa tattgctgca gcttgggatg cacatgataa aatccctaac
    14341 aatggtcgta taaactttta aaatgcgaga atgaaagcac tttgtatttt ttattgtata
    14401 tgttagcttg gacagtgctt gcaatgataa tccgtggagg aataaatgga tttgatgaac
    14461 acacttggcg taatatttta gctagtgcgt tgtcctcgct atatatacat tatatatcca
    14521 tagataaaaa tagaaaaagt ccaaaagaaa aaagaaaaaa tagatttgtt catggtaggg
    14581 acttatgaaa gctttactga caaaaaagaa aacagtttac aaagaaaaat gatggaggag
    14641 caaacatggc acaaaaagga gtaagcctta tcaaggcagc atttgataca gataactttc
    14701 tcatgcgttt tagtgagaag gtcttggaca tcgtgacagc caatcttctt tttgtcgtct
    14761 cttgtttacc catcgtgacg attggagtgg ctaaaatcag cctctacgag accatgttcg
    14821 aagttaagaa gagcagacgg gtgcctgttt ttaaaatcta tctaagatct ttcaagcaaa
    14881 atctgaaact aggtcttcag ctgggtttaa tggagttagg aattgtgttt cttacccttt
    14941 cagatctcta tcttttctgg ggtcaaacag ctctgccctt ccaattgctg aaagccattt
    15001 gtttaggtat tctgattttt cttactatcg tgatgctggc tagttaccct atcgcggcac
    15061 gttatgacct atcttggaaa gaaattcttc aaaaaggatt gatgttggct agttttaact
    15121 ttccttggtt cttcctcatg ttagccattc ttgtcctcat tgtgatggtt ctttatctgt
    15181 ccgccttcag tctactctta ggtggctcag tcttcctact ttttgggttt ggactattgg
    15241 tctttatcca gactggattg atggagaaaa ttttcgcaaa ataccaatag gagctttatt
    15301 tctgaaacta ctttcaaagg ctccaaacgc tattctataa gcgagaaact aaaatctaag
    15361 tgtctataag atattgaaag ccttttcggt aaagtgtata ctaaagaagt aaagaaaaat
    15421 ctgctttagc agaaaataaa aataatagga gaaaatctat gtcagatttg aaaaaatacg
    15481 aaggtgtcat tccagccttc tacgcatgtt atgatgatca aggagaagta agcccagaac
    15541 gtacgcgtgc cttggttcaa tacttcattg ataaaggtgt tcaaggtctt tatgtcaatg
    15601 gttcttctgg tgaatgtatc taccaaagcg ttgaagatcg caagttgatt ttggaagaag
    15661 tcatggcggt agccaaaggt aaattgacca ttattgccca tgttgcttgc aataatacta
    15721 aagatagtat ggaacttgct cgccatgctg aaagcttggg agtagatgct attgcaacga
    15781 ttccaccaat ttatttccgc ttgccagaat actcagttgc caaatactgg aacgatatca
    15841 gttctgcagc tccaaacaca gactacgtga tttacaacat tcctcaattg gcaggggttg
    15901 ctttgactcc aagcctttac acagaaatgt tgaaaaatcc tcgtgttatc ggtgtgaaga
    15961 actcttctat gccagttcaa gatatccaaa cctttgtcag ccttggtgga gaagaccata
    16021 tcgtctttaa tggtcctgat gagcagttcc taggaggacg cctcatgggg gctagggctg
    16081 gtatcggtgg tacttatggt gctatgccag aactcttctt gaaactcaat cagttgattg
    16141 cggataagga cctagaaaca gcgcgtgaat tgcagtatgc tatcaacgca atcattggta
    16201 aactcacttc tgctcatgga aatatgtacg gtgtcatcaa agaagtcttg aaaatcaatg
    16261 aaggcttgaa tattggatct gttcgttcac cattgacacc agtgactgaa gaagatcgtc
    16321 cagttgtaga agcggctgct gccttgattc gtgaaaccaa ggagcgcttc ctctaatcta
    16381 aaaggaggta tttatgacat attacgttgc aattgatatc ggtggaacca acatcaagta
    16441 tggtttggtt gatcaagagg ggcaacttct tgaatcgcat gaaatgccaa ctgaggcgca
    16501 taagggtgga cctcatatct tacaaaagac caaagatatc gtagctagtt atttagaaaa
    16561 aggcccagta gcaggtgttg ccatatcttc tgctgggatg gtggatccgg ataagggtga
    16621 gattttctat gctgggccgc aaatccctaa ctacgcaggc acccagttca aaaaggaaat
    16681 cgaagaaagc tttactattc cttgtgagat tgaaaatgat gtcaactgtg caggtcttgc
    16741 tgaggcagta tctggttcag gcaagggagc aagtatgaca ctttgcttga ccattggaac
    16801 cggtatcggt ggttgtttga ttatggatag gaaagtcttc catggtttta gtaattcagc
    16861 ctgtgaagtc gggtatatgc atatgcagga tggagctttt caggatctcg cttctacaac
    16921 agctttagtg aaatatgtag ctgaagccca tggagaagat gttgatcagt ggaatggccg
    16981 acgtatcttt aaggaagcta ctgaaggaaa caaaatctgc atggaaggca ttgaccgtat
    17041 ggttgactat ctaggaaaag gtctggcaaa tatttgctac gttgccaatc cagaagtggt
    17101 tattcttggt ggtggtatca tggggcaaga ggctatcctc aaacctaaga tccgcacagc
    17161 cttgaaagag gctttggtac caagtttagc agaaaaaaca cgattagaat ttgcccatca
    17221 ccaaaataca gcagggatgt tgggtgcata ttatcatttt aagacaaaac aatcctagtt
    17281 tggctcagcc aaactaggat tttcttacac gtttttgtct acgatagccg ttgagttttt
    17341 tattttccca gtagctatta aagatttttt ccttgctttc gcgattgatt tccaaaaagt
    17401 aggcataaat caaatcgata aagaagagca taggaagttg agcggatatt cgttggatat
    17461 aggagggttg gctgtgggtg gctacaagaa cagtctctgt ataggtctgg ctatctttat
    17521 tgggaacact tgtaaagagt acagtctttg cccccatctc cttggcatct aatagactat
    17581 ctaaaataga aggagttgag cctgaaagtg agaagcccag tactagacaa ttttcatcca
    17641 tgatgctggt tgtccaggca aagccgtctt ggtctgtcaa agcttcgcag accacaccta
    17701 gtcgcataaa acgtaatttc atttcacggg cgacgaggcc agaactccct gttccaaaga
    17761 agtagatacg ctcagcatct tcgattagct gggcaattcg ctctagttgg atttcgtcaa
    17821 tcaagtcttg tgtttgttcc ctcatattgc tataacttct gaggactcgt ttggtcagtg
    17881 gactgtgctt ggagacttgg ttggcttgat tttctgcctg atgttggtat tggaaaataa
    17941 attctcggta gccagtaaag ccacactttt tagcaaagcg ggtcaaagca gcttgagaaa
    18001 tatgtaattt ttgggtgact tgttgagaag ataaatcatc tgtaatcgtt tcagcttgca
    18061 aaaaatagcg agcgatttct tgctctaggt ctgtcatttc ttcaaaatgt gaatcaatga
    18121 tagttgcgat atctggtttg tccataggga aagctccttt acatgagtca tactggaaga
    18181 ctagatcagg gaatagtcac acttcattat aacacataat ataaggatag ataaataaaa
    18241 acgcatctct gttttaaaaa cgaaaaaatc gaaaaagctt ctctcttttc cataattttc
    18301 tactcaaatt gtggtacaat taagagtaag attttaagtt agaaatgaga ctgatttgta
    18361 tgagaaaatt taacagccat tcgattccga ttcggcttaa tttattgttt tcaatcgtca
    18421 ttttactctt tatgaccatt attggtcgtt tgttgtatat gcaggttttg aacaaggatt
    18481 tttacgaaaa aaagctagcc tcagctagtc agaccaagat tacaagcagt tcagcccgtg
    18541 gggaaattta tgatgctagt ggaaaacctt tggtagaaaa tacgttaaag caggttgttt
    18601 cctttacgcg tagcaataaa atgacggcta cagacttaaa agaaacagct aaaaagttac
    18661 tgacttatgt gagcatcagt tctccaaatt tgacagaacg ccagctggcg gattactatt
    18721 tggctgatcc tgaaatctat aaaaaaatag tggaagctct cccaagtgag aaacgcttgg
    18781 attcagatgg caatcgtcta tccgaatcag aactgtataa caatgcggtc gatagtgtac
    18841 aaacgagtca actaaattat acagaggatg aaaagaaaga aatctatctt tttagtcagt
    18901 taaatgctgt tggaaacttt gcgacaggaa ccattgcgac agatcctcta aatgattctc
    18961 aggtggctgt tattgcctct atttcaaagg agatgcctgg cattagtatt tctacttctt
    19021 gggatagaaa ggttttggaa acttcccttt cttctatagt tgggagtgta tccagtgaaa
    19081 aagctggtct cccagcggaa gaagcagaag cctatcttaa aaaaggctat tctctaaatg
    19141 atcgtgtagg aacctcctat ttggaaaagc aatatgaaga gaccttacaa ggaaaacgct
    19201 cggtaaaaga aatccatctg gataaatatg gaaatatgga aagcgtggat acaattgagg
    19261 aaggtagtaa gggaaacaat atcaaactga ccattgattt ggccttccaa gatagcgtgg
    19321 atgctttact gaaaagttat ttcaattccg agctagaaaa tggtggagcc aagtattctg
    19381 aaggtgtcta tgcagtcgcc cttaacccaa aaacaggtgc ggttttgtct atgtcaggga
    19441 ttaaacatga cttgaaaacg ggagagttga cgcctgattc cttgggaacg gtaaccaatg
    19501 tctttgttcc aggttcggtt gtcaaggcgg cgaccatcag ctcaggttgg gaaaatggag
    19561 tcttgtcagg aaaccagacc ttgacagacc agtccattgt cttccaaggt tcagctccca
    19621 tcaattcttg gtatactcag gcttacggtt cattccctat cacagcggtc caagctctgg
    19681 agtattcatc aaatacctat atggtccaaa cagccttagg tcttatgggg caaacctatc
    19741 aacccaatat gtttgtcggc accagcaatc tagagtctgc tatggagaaa ctgcgttcaa
    19801 cctttggcga atatggcttg ggtactgcga caggaattga cctaccagat gaatctactg
    19861 gatttgttcc caaagagtat agctttgcta attacattac taatgccttt gggcagtttg
    19921 ataactatac gccgatgcag ttggctcagt atgtagcaac tattgcaaat aatggtgttc
    19981 gtgtggctcc tcgtattgtt gaaggcattt atggtaataa tgataaggga ggactgggtg
    20041 acttgattca gcaactgcaa ccgacagaga tgaataaggt caatatatcc gactccgata
    20101 tgagcatctt gcaccaaggt ttttatcagg ttgcccatgg tactagtgga ttgacaactg
    20161 gacgtgcctt ttcaaatggt gccttggtat ccattagcgg aaaaacaggt acagccgaaa
    20221 gctatgtggc agatggtcag caagcaacca ataccaatgc ggtggcctat gccccatctg
    20281 ataatcccca aatcgctgtc gcagtggtct ttcctcataa taccaatcta acaaatggtg
    20341 taggaccttc cattgcgcgt gacattatca atctgtatca aaaataccat ccaatgaact
    20401 agaaaggaaa ttatgcttta tccaacacct attgccaagt tgattgacag ttattctaag
    20461 ttaccaggta tcgggattaa gacggctacg cgtctggcct tttatacgat tgggatgtct
    20521 gctgatgatg tcaatgaatt tgcaaaaaat ctcctttctg ctaagagaga attgacatat
    20581 tgttctattt gtggacgttt gacagacgac gatccttgtt ctatctgtac tgatccgact
    20641 cgtgaccaga caacaatttt agttcttgag gatagtagag atgtggcagc catggaaaat
    20701 atccaagaat accatggact ctatcatgtc cttcatggcc tcatttctcc tatgaatggt
    20761 atcagtccgg acgatatcaa tctcaagagc cttatgactc gtcttatgga tagtgaggtt
    20821 tcagaagtga ttgtggcgac taatgctaca gcggatggtg aagcgacttc catgtatctt
    20881 tcacgtttgc tcaagccggc tggtatcaag gttacgcgtc tagcacgagg tctcgctgtg
    20941 ggagcggaca ttgagtatgc ggacgaagtg acactcttac gagcgattga aaatcggaca
    21001 gagttgtaag tgtaggcaaa tttacgaact cccttcattt ataaaaaatc aaagaggctg
    21061 aaaatcgttc ctatcggcct cttttcgtat agtgtgatga gtaggatcag gttcaagttt
    21121 taaaaaacca agcaaatatg atatactaaa gagcgagtat tctagtagaa ttaggacaaa
    21181 taatatgaaa caaacgatta ttcttttata tggtggacgg agtgcggaac gcgaagtctc
    21241 tgtcctttca gctgagagtg tcatgcgtgc ggtcaattac gaccgtttca cagtcaagac
    21301 tttctttatc agtcagtcag gtgactttat caaaacgcag gaatttagtc atgctccggg
    21361 gcaagaagac cgtctcatga ccaatgaaac cattgattgg gataagaaag ttgcaccaag
    21421 tgctatctac gaagaaggtg cagtggtctt tccagtcctt cacgggccaa tgggagaaga
    21481 tggctctgtt caaggattct tggaagtttt gaaaatgcct tacgttggtt gcaacatttt
    21541 gtcatcaagt cttgccatgg ataaaatcac gactaagcgt gttctggaat ctgctggtat
    21601 tgcccaagtt ccttatgtgg ctatcgttga aggcgatgat gtgactgcta aaatcgctga
    21661 agtggaagaa aaattggctt atccagtctt cactaagccg tcaaacatgg ggtctagtgt
    21721 cggtatttct aggtctgaaa accaagaaga actccgtcaa gccttaaaac ttgccttccg
    21781 atatgacagc cgtgtcttgg ttgagcaagg agtgaatgcc cgtgaaattg aggttggcct
    21841 cttgggtaac tacgatgtca agagcacgct acctggagaa gttgtcaagg acgttgcctt
    21901 ttatgactac gatgccaagt atattgataa caaggttact atggatattc ctgccaaaat
    21961 cagtgatgat gtggtggctg tcatgcgtca aaatgcagaa acagccttcc gtgccattgg
    22021 tggccttggt ctatctcgtt gcgatttctt ctatacagat aagggagaga tttttctcaa
    22081 cgagctcaat accatgccag gttttaccca gtggtctatg tacccactac tttgggacaa
    22141 tatggggatc agctacccag aactaatcga gcgtttggtt gaccttgcca aggaaagttt
    22201 tgacaagcgc gaagcgcatt tgatataaaa tgaaagagag ggtagaagcc agaaccatca
    22261 ctgcacggtg actagagttc tcggacttca gcccttttta aaggagtaga aatgaaatta
    22321 acaatccatg aaattgccca agttgttgga gccaaaaatg atatcagtat ctttgaggac
    22381 acccagttag aaaaagctga gtttgatagt cgtttgattg gaactggaga tttatttgtg
    22441 ccacttaaag gtgcgcgtga tggccatgac tttattgaaa cagcctttga aaatggtgca
    22501 gcagtaacct tgtctgagaa agaggtctca aatcatcctt acattctagt agatgatgtt
    22561 ttgacagcct ttcaatccct agcatcctac tatcttgaaa aaacgactgt tgatgtcttt
    22621 gctgttacag gttcaaatgg caagacaacg actaaggata tgttggcgca tttactgtca
    22681 acgacctaca agacctacaa aacacaaggc aactacaata acgagattgg ccttccctac
    22741 acagttctac acatgcctga aggaacagaa aagttggttt tggagatggg gcaggaccac
    22801 ttgggcgata ttcatctctt gtctgaattg gctcgtccaa aaacagccat cgtgaccttg
    22861 gttggagaag cccatttggc ctttttcaaa gaccgttcag agattgctaa gggaaaaatg
    22921 caaattgcag acggaatggc ttcaggttcc ttgcttttag tgccggctga ccctatcgta
    22981 gaggactatt tgccaactga taaaaaggtg gtccgttttg ggcaaggggc agagttggaa
    23041 atcacagact tggttgagcg taaggacagt ctgaccttta aggctaattt cttggaacaa
    23101 gcccttgatt tgccagtgac tggtaagtac aatgctacca atgctatgat tgcatcctat
    23161 gttgccctac aagaaggagt ttcagaggag caaattcatc aggccttcca aggtcttgaa
    23221 ttgacgcgta atcgtactga gtggaagaaa gcagccaatg gagcagatat cctgtcagac
    23281 gtatataatg ccaatccaac tgctatgaag ctgattttag agactttctc tgccattcca
    23341 gccaatgaag gtggcaagaa aattgcagtg ttggcggata tgaaggagct tggtgaccag
    23401 tctattcaac tccataacca gatgattttg agcctttctc cagatgtgct tgataccgtt
    23461 attttctatg gagaagacat tgctgaatta gcccaattgg ccagtcaaat gttcccaatt
    23521 ggccacgttt actacttcaa gaaaacagaa gaccaagacc aatttgaaga cctagtcaag
    23581 caggtcaagg aaagcctcag tgccaatgat caaatcttgc tcaagggctc taactctatg
    23641 aacctagcca tgttggtaga aagtttagaa aatgaaacca agtgattttg ttaagtatct
    23701 gcaaagaatg attgccctta cagatactgg cttaaccttt acaaaggatc cttttgaccg
    23761 tgagcgctac gaggacttgc gaagtctgtt atctgaaatg ttgaatcagg gatcagacct
    23821 ggatgcagaa gaagtagcag aagtcttgaa accaacttca gcttatgcga ctcccttaat
    23881 ggacgtccgt gcttggattg ttgaggatga gaagatttgt ctggttaggg gacaaggaga
    23941 ggatagttgg gctttgccag gtggctttgg tgaagtcggc tattctccaa ctgaaaatat
    24001 tctcaaggaa attgaagaag aaaccggttt taaagccaaa gttgaaagac tgctagctgt
    24061 ttttgatacc aatcgtttcc aactacagag caaacaatat gcaaagtttg tttttgaatg
    24121 taagcttctc gatggacaat tccaagaaaa tcaagaaatc gctgaccttc aattttttgc
    24181 aattgaccaa ctgccgaatt tatctgaaaa acgcattacc aaggagcaaa tcgagattct
    24241 ttggcaggtt tatcaaggtc agatggagca atatcttgac taagaagatg attatcgtat
    24301 ttctaaattc atttttctta agtagcatgg tataataaaa tgcaggaaaa ttttgaatta
    24361 tgaggaagac tagatgaatt tatgggatat tttctttacg actcaggcaa ccgagccgcc
    24421 caaatttgac cttttttggt atgttagcct atttacgctc ttagccttaa ccatttatac
    24481 agcccatcgc tatcgtgaaa agaaggttta ccaacgattt ttccaaatct tgcagactgt
    24541 tcagttaatc cttctttatg gttggtactg ggtcaatcat atgccactgt cagaaagcct
    24601 acccttttac cattgccgta tggctatgtt tgtggtactc ttgcttcctg gtcagtccaa
    24661 atataaacaa tactttgcat tattgggaat atttgggaca ttagcagcct ttgtttatcc
    24721 agtgccagat gcttaccctt ttccacatat caccatttta tcctttatct ttggtcattt
    24781 agcactcttg gggaactctc tagtttatct attgagacag tataatgcgc gattgctgga
    24841 tgtgaaggga atttttctca tgacctttgc tctaaatgcc ttgatttttg tggtcaattt
    24901 ggtgacaggc ggcgattacg gatttttgac aaaaccgcca ttggttgggg atcacggtct
    24961 agtagctaat tatttacttg tttcaattgt gctggtagct actatcagtt tgactaagaa
    25021 aatcttagaa ttctttttag ctcaagaagc agaaaaaatg attgcaaagg aagcttaaca
    25081 cagagctttc ttttttgctc ttagagagtt tttacaagca gcttataaaa taagaatttc
    25141 tgaatagaca aactcaaaaa atggctggga aatttaggaa aaaaacaagc acgattaaat
    25201 tttttgtgtt ataatatttt gtgaatagct atgcctatgt ttagctatgg aataatacga
    25261 agtgcgaaac ttggaagata gagaggaagc gatgtaatgg ctagagaagg cttttttaca
    25321 ggtctagata ttggaacaag ctctgtcaag gtgcttgtgg ccgagcagag aactggtgaa
    25381 ttaaatgtaa ttggcgtgag taatgccaaa agtaaaggtg taaaggatgg aattattgtt
    25441 gatattgatg cagcagcaac tgctatcaag tcagccattt cccaagcgga agaaaaggca
    25501 ggcatttcga ttaaatcagt aaatgtcggc ttgcctggta atcttttgca ggtagaacca
    25561 actcagggga tgattccagt aacatctgat actaaggaaa ttacggatca agatgttgaa
    25621 aatgttgtca aatcagcttt gacaaagagt atgacacctg accgtgaagt cattaccttt
    25681 attcctgaag aatttattgt ggatggtttc caagggattc gtgacccacg tggcatgatg
    25741 ggggttcgcc ttgaaatgcg tggtttgctt tatacaggac ctcgtactat cttgcacaat
    25801 ttgcgtaaga cggttgagcg tgcaggtgtt caggttgaaa atgttatcat ttcaccacta
    25861 gcaatggttc agtctgtttt gaacgaaggg gaacgtgaat ttggtgctac agtgattgat
    25921 atgggggcag gtcaaacgac tgtcgctaca atccgtaatc aagaactcca gttcacacat
    25981 attctccaag aaggtggaga ttatgtaact aaagatatct ccaaggtttt gaaaacctct
    26041 cgcaaattag cggaaggctt gaaactgaat tacggggaag cctatccgcc tcttgcaagc
    26101 aaagaaacct tccaagtaga ggttattgga gaagtagaag cagtcgaagt gacggaagcc
    26161 tacttgtcag aaattatttc tgcacgaatc aagcacatcc ttgaacaaat caagcaagaa
    26221 ttagatagaa ggcgtctatt ggacctccct ggtggtattg tcttaatcgg tgggaatgcc
    26281 attttaccag gtatggttga gcttgctcag gaagtctttg gcgtccgtgt caagctttat
    26341 gttccaaatc aagttggtat ccgtaatcca gcctttgcgc atgtgattag tttatcagaa
    26401 tttgcgggtc aattaacaga agttaatctt ttggctcagg gagcgataaa aggtgagaat
    26461 gacttaagtc atcagccaat tagttttggt gggatgctgc aaaaaacagc tcagtttgta
    26521 caatcaacgc ctgttcaacc agctcctgct ccagaagtag agccggtggc gcctacagaa
    26581 ccaatggcgg atttccaaca agcttcacaa aataaaccga aattagcaga tcgtttccgt
    26641 ggcttgatcg gaagcatgtt tgacgaataa agaggaaaaa taaattatga cattttcatt
    26701 tgatacagct gctgctcaag gggcagtgat taaagtaatt ggtgtcggtg gaggtggtgg
    26761 caatgccatc aaccgtatgg tcgacgaagg tgttacaggc gtagaattta tcgcagcaaa
    26821 cacagatgta caagcattga gtagtacaaa agctgagact gttattcagt tgggacctaa
    26881 attgactcgt ggtttgggtg caggaggtca acctgaggtt ggtcgtaaag ccgctgaaga
    26941 aagcgaagaa acactgacgg aagctattag tggtgccgat atggtcttca tcactgctgg
    27001 tatgggagga ggctctggaa ctggagctgc tcctgttatt gctcgtatcg ccaaagattt
    27061 aggtgcgctt acagttggtg ttgtaacacg tccctttggt tttgaaggaa gtaagcgtgg
    27121 acaatttgct gtagaaggaa tcaatcaact tcgtgagcat gtagacactc tattgattat
    27181 ctcaaacaac aatttgcttg aaattgttga taagaaaaca ccgcttttgg aggctcttag
    27241 cgaagcggat aacgttcttc gtcaaggtgt tcaagggatt accgatttga ttaccaatcc
    27301 aggattgatt aaccttgact ttgccgatgt gaaaacggta atggcaaaca aagggaatgc
    27361 tcttatgggt attggtatcg gtagtggaga agaacgtgtg gtagaagcgg cacgtaaggc
    27421 aatctattca ccacttcttg aaacaactat tgacggtgct gaggatgtta tcgtcaacgt
    27481 tactggtggt cttgacttaa ccttgattga ggcagaagag gcttcacaaa ttgtgaacca
    27541 ggcagcaggt caaggagtga acatctggct cggtacttca attgatgaaa gtatgcgtga
    27601 tgaaattcgt gtaacagttg tcgcaacggg tgttcgtcaa gaccgcgtag aaaaggttgt
    27661 ggctccacaa gctagatctg ctactaacta ccgtgagaca gtgaaaccag ctcattcaca
    27721 tggctttgat cgtcattttg atatggcaga aacagctgaa ttgccaaaac aaaatccacg
    27781 tcgtttggaa ccaactcagg catctgcttt tggtgattgg gatcttcgcc gtgaatcgat
    27841 tgttcgtaca acagattcag tcgtttctcc agtcgagcgc tttgaagccc caatttcaca
    27901 agatgaagat gaattggata cacctccatt tttcaaaaat cgttaagtaa atgaatgtaa
    27961 aagaaaatac agaacttgtt tttcgagaag ttgcagaggc tagtctgagt gctaatcgag
    28021 agagtggttc ggtctctgtc attgcagtta ccaagtatgt agatgtaccg acagcggaag
    28081 ccttgcttcc gctaggtgtt catcatatcg gtgaaaatcg tgtagataag tttctggaaa
    28141 aatatgaagc tttaaaagat cgagatgtga cttggcattt gattggtacc ttgcaaagac
    28201 gtaaggtgaa agatgtcatt caatacgttg attatttcca tgcattggac tcagtaaagc
    28261 tagcagggga aattcaaaaa agaagtgacc gagtcatcaa gtgtttcctt caagtaaata
    28321 tttctaaaga agaaagcaaa cacggttttt cgagagagga actgatggaa atcttgccag
    28381 agttagccag actagataag attgaatatg ttggtttaat gacgatggca ccttttgagg
    28441 ctagcagtga gcagttgaaa gagattttca aggcgaccca agatttacaa agagaaattc
    28501 aagagaaaca aattccaaat atgcctatga ccgagttaag tatgggaatg agtcgtgatt
    28561 ataaagaagc gattcaattc ggttccactt ttgttcgtat aggtacatca ttttttaagt
    28621 aggagagaac catgtcttta aaagatagat tcgatagatt tatagattat tttacggaga
    28681 atgaggattc aagtctccct tatgaaaaaa gagatgagcc tgtgtttact ccagtaaatt
    28741 cttcacagga accggctctc ccaatgaatc aaccttcaca gtcggctggt acaaaagaga
    28801 acaatatcac cagacttcat gcaagacaac aggaattggc aaatcagagt cagcgtgcaa
    28861 cggataaggt cattatagat gttcgttatc ctagaaaata tgaggatgca acagaaattg
    28921 ttgatttatt ggcaggaaac gaaagtatct tgattgattt tcagtatatg acagaggtgc
    28981 aggctcgtcg ttgtttggac tatttggatg gagcttgtca tgttttagct ggaaatttga
    29041 aaaaggtagc ttctaccatg tatttgttga caccagtgaa tgttattgta aatgttgaag
    29101 atatccgttt accagatgaa gatcaacagg gtgagttcgg ttttgatatg aagcgaaata
    29161 gagtacgata atgatttttt taattcgtat gatttataat gcagtggata tttactccct
    29221 gattttggta gccttcgctg tcatgtcttg gtttccaggt gcctacgaat ccagtttagg
    29281 tcgttggatt gtagcgttgg tgaaaccagt gcttgctccc ttgcaacgcc tgcctttaca
    29341 gatagcgggt cttgatttat ctatttgggt cgcgattgtt ttggttcgat ttttaggaga
    29401 aaacctagtg cgttttctgg cgatgatagg atgaataaag ggatttatca gcatttctcc
    29461 atagaagatc gtccatttct tgacaaggga atggaatgga taaagaaggt agaagatagc
    29521 tatgctcctt ttttaactcc ttttatcaat cctcatcagg agaagctatt aaagattttg
    29581 gccaaaacct atggtcttgc ttgtagcagt agtggggaat tcgtctcgag tgagtatgtt
    29641 cgagttttat tatacccaga ttatttccaa ccagagtttt cagattttga aatatctctc
    29701 caggaaattg tgtattccaa taaatttgaa catttaacgc atgctaagat tttagggaca
    29761 gtcatcaatc aattagggat tgaacggaaa ctttttggag atatcctagt agatgaagaa
    29821 cgggcgcaga ttatgattaa tcagcagttt cttcttctct ttcaagatgg actaaagaaa
    29881 attggtcgta tacctgtttc gctggaggaa cgtcctttca ccgagaaaat agataagcta
    29941 gaacagtatc gagaactgga tttatctgtg tctagttttc gattagatgt tcttttatca
    30001 aatgttttga aactatctag gaatcaagca aaccagttga ttgaaaagaa acttgtccaa
    30061 gtaaattatc atgtggtaga caaatcagat tacactgttc aagttggaga cttgattagt
    30121 gtgagaaaat ttggtcgctt gagattactt caagataagg gacaaacgaa aaaagagaag
    30181 aaaaaaataa ccgtccagtt attattaagt aagtgaggaa tagaatgcca attacatcat
    30241 tagaaataaa ggacaagact tttggaactc gattcagagg ttttgatcca gaagaagtcg
    30301 atgaattttt agatattgtg gttcatgatt acgaagatct tgtgcgtgcg aatcatgata
    30361 aaaatttgcg tattaagagt ttagaagagc gtttgtctta ctttgatgaa ataaaagatt
    30421 cattgagcca gtctgtattg attgctcagg atacagctga gagagtgaaa caggcggcgc
    30481 atgaacgttc aaacaatatc attcatcaag cagagcaaga tgcgcaacgc ttgttggaag
    30541 aagctaaata taaggcaaac gagattcttc gtcaagcaac tgataatgct aagaaagtcg
    30601 ctgttgaaac agaagaattg aagaacaaga gccgtgtctt ccaccaacgt ctcaaatcta
    30661 caattgagag tcagttggct attgttgaat cttcagattg ggaagatctt ctccgtccaa
    30721 cagctactta tcttcaaacc agtgatgaag cctttaaaga agtggttagc aaagtacttg
    30781 gagaaccgat tccagctcca attgaagaag aaccaattga tatgacacgt cagttctctc
    30841 aagcagaaat ggcagagtta caagctcgta ttgaggtagc cgataaagaa ttggctgaat
    30901 ttgaagctca gattaaacag gaagtggaag ctccaacttg tagtgagtcc tcaggttgaa
    30961 gaagagcctc tgctcatcca gttggcccaa tgtatgaaga accagaagta gctccagtgc
    31021 atccgacagg tccaacacca gctacagaaa ctgttgattc aataccggga tttgaagcac
    31081 cgcaagaatc tgttacaatt ttataagaaa tattctgaga acaatatctt atccttatat
    31141 ttccagcgag caggaaatgg tgtgagtcct gcattcccta tcgataagat tatcctctca
    31201 aactatcaag tctgaatcta gtaagatttg acgttcccca cgttacggga taagagagag
    31261 aaagactaaa tctttttccg aataaaggtg gtaccacgat tttcgtcctt tttggaagtc
    31321 gtggttttta atttgttatt atttataaag gagataccat gaaactcaaa gacaccctta
    31381 atcttgggaa aactgaattc ccaatgcgtg caggccttcc taccaaagag ccagtttggc
    31441 aaaaggaatg ggaagatgca aaactttatc aacgtcgtca agaattgaac caaggaaaac
    31501 ctcatttcac cttgcatgat ggccctccat acgctaacgg aaatatccac gttggacatg
    31561 ctatgaacaa gatttcaaaa gatatcattg ttcgttctaa gtctatgtca ggattttacg
    31621 cgccatttat tcctggttgg gatactcatg gtctgccaat cgagcaagtc ttgtcaaaac
    31681 aaggtgtcaa acgtaaagaa atggacttgg ttgagtactt gaaactttgc cgtgagtacg
    31741 ctctttctca agtagataaa caacgtgaag attttaaacg tttgggtgtt tctggtgact
    31801 gggaaaatcc atatgtgacc ttgactcctg actatgaagc agctcaaatt cgtgtatttg
    31861 gtgagatggc taataagggt tatatctacc gtggtgccaa gccagtttac tggtcatggt
    31921 catctgagtc agcccttgct gaagcagaga ttgaatacca tgacttggtt tcaacttccc
    31981 tttactatgc caacaaggta aaagatggca aaggagttct agatacagat acttatatcg
    32041 ttgtctggac aacgactcca tttaccatca cagcttctcg tggtttgacg gttggtgcag
    32101 atattgatta cgttttggtt caacctgctg gtgaagctcg taagtttgtc gttgctgctg
    32161 aattattgac tagcttgtct gagaaatttg gctgggctga tgttcaagtt ttggaaactt
    32221 accgtggcca agaacttaac cacatcgtaa cagaacaccc atgggataca gctgtagaag
    32281 agttggtaat tcttggtgac cacgttacga ctgactctgg tacaggtatt gtccatacag
    32341 cccctggttt tggtgaggac gactacaatg ttggtattgc taataatctt gaagtcgcag
    32401 tgactgttga tgaacgtggt atcatgatga agaatgctgg tcctgagttt gaaggtcaat
    32461 tctatgaaaa ggtagttcca actgttattg aaaaacttgg taacctcctt cttgcccaag
    32521 aagaaatctc tcactcatat ccatttgact ggcgtactaa gaaaccaatc atctggcgtg
    32581 cagttccaca atggtttgcc tcagtttcta aattccgtca agaaatcttg gacgaaattg
    32641 aaaaagtgaa attccactca gaatggggta aagtccgtct ttacaatatg atccgtgacc
    32701 gtggtgactg ggttatctct cgtcaacgtg cttggggtgt tccacttcca atcttctatg
    32761 cagaagacgg tacagctatc atggtagctg aaacgattga acacgtagct caactttttg
    32821 aagaacatgg ttcaagcatt tggtgggaac gtgatgccaa agatctcttg ccagaaggat
    32881 ttactcatcc aggttcacca aacggcgagt tcaaaaaaga aactgatatc atggacgttt
    32941 ggtttgactc aggttcatca tggaatggag tggtggtaaa ccgtcctgaa ttgacttacc
    33001 cagccgacct ttacctagaa ggttctgacc aataccgtgg ttggtttaac tcatcactta
    33061 tcacatctgt tgccaaccat ggcgtagcac cttacaaaca aatcttgtca caaggttttg
    33121 cccttgatgg taaaggtgag aagatgtcta aatctcttgg aaataccatt gctccaagcg
    33181 atgttgaaaa acaattcggt gctgaaatct tgcgtctctg ggtaacaagt gttgactcaa
    33241 gcaatgacgt gcgtatctct atggatattt tgagccaagt ttctgaaact taccgtaaga
    33301 ttcgtaacac tcttcgtttc ttgattgcca atacatctga ctttaaccca gctcaagata
    33361 cagtcgctta cgatgaactt cgttcagttg ataagtacat gacgattcgc tttaaccagc
    33421 ttgtcaagac cattcgtgat gcctatgcag actttgaatt cttgacgatc tacaaggcct
    33481 tggtgaactt tatcaacgtt gacttgtcag ccttctacct tgattttgcc aaagatgttg
    33541 tttacattga aggtgccaaa tcactggaac gccgtcaaat gcagactgtc ttctatgaca
    33601 ttcttgtcaa aatcaccaaa ctcttgacac caatccttcc tcacactgcg gaagaaattt
    33661 ggtcatatct tgagtttgaa acagaagact tcgtccaatt gtcagaatta ccagaggctc
    33721 aaacttttgc taatcaagaa gaaatcttgg atacatgggc agccttcatg gacttccgtg
    33781 gacaagctca aaaagccttg gaagaagctc gtaatgcaaa agtaatcggt aaatcacttg
    33841 aagcacactt gacagtttat ccaaacgaag ttgtgaaaac tctactcgaa gcagtaaaca
    33901 gcaatgtggc tcaacttttg atcgtgtcag acttgaccat cgcagaagga ccagctccag
    33961 aagctgccct tagcttcgaa gatgtagcct tcacagttga acgcgctgca ggtgaagtat
    34021 gtgaccgttg ccgtcgtatt gacccaacaa cagcagaacg tagctaccag gcagttatct
    34081 gtgaccactg tgcaagcatc gtagaagaaa actttgcgga agcagtcgca gaaggatttg
    34141 aagagaaata agattgaaaa gtctaggcaa aattcaattt gagaagaaaa gacaactaat
    34201 tttatagtct attaaacgca ttgtatcacg tttttgaaca cctgatatga tgcgtttttt
    34261 atttatttta aaaatttgcg aggtatgact ttttatactc aacaagaatc aaagagaaac
    34321 ttagcaagct aacagtagta agataaaata ggaatttgat attagggata agattggtaa
    34381 atagtgtaat atttttacaa caataaattt atatagttat ttct
//
LOCUS       DAVKMO010000018        31897 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVKMO010000018 DAVKMO010000000
VERSION     DAVKMO010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31897
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.018"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            227..1708
                     /locus_tag="VW361_000985"
     CDS             227..1708
                     /locus_tag="VW361_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9744048.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2069..3070
                     /locus_tag="VW361_000986"
     CDS             2069..3070
                     /locus_tag="VW361_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9744049.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3220..4137
                     /locus_tag="VW361_000987"
     CDS             3220..4137
                     /locus_tag="VW361_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9744050.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4148..5038
                     /locus_tag="VW361_000988"
     CDS             4148..5038
                     /locus_tag="VW361_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9744051.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5067..6683
                     /locus_tag="VW361_000989"
     CDS             5067..6683
                     /locus_tag="VW361_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9744052.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNVNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6693..8012
                     /locus_tag="VW361_000990"
     CDS             6693..8012
                     /locus_tag="VW361_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9744053.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMVFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8220..8292)
                     /locus_tag="VW361_000991"
     tRNA            complement(8220..8292)
                     /locus_tag="VW361_000991"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8257..8259),aa:Lys,seq:ctt)
     gene            complement(8557..9828)
                     /locus_tag="VW361_000992"
     CDS             complement(8557..9828)
                     /locus_tag="VW361_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU9744054.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFNFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10098..10337
                     /locus_tag="VW361_000993"
     CDS             10098..10337
                     /locus_tag="VW361_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744055.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10502..10681
                     /locus_tag="VW361_000994"
     CDS             10502..10681
                     /locus_tag="VW361_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744056.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10818..10997
                     /locus_tag="VW361_000995"
     CDS             10818..10997
                     /locus_tag="VW361_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU9744057.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGE
                     LNKYTERGIRKQAGL"
     gene            11034..11486
                     /locus_tag="VW361_000996"
     CDS             11034..11486
                     /locus_tag="VW361_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU9744058.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11777..12247
                     /locus_tag="VW361_000997"
     CDS             11777..12247
                     /locus_tag="VW361_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU9744059.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     SLFLKDTAEVGLDVLMDFLEDPEAEEFIMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12266..13369
                     /locus_tag="VW361_000998"
     CDS             12266..13369
                     /locus_tag="VW361_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU9744060.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERATTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNFWFPRL"
     gene            13335..13763
                     /locus_tag="VW361_000999"
     CDS             13335..13763
                     /locus_tag="VW361_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9744061.1"
                     /translation="MELEISGFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            13901..14851
                     /locus_tag="VW361_001000"
     CDS             13901..14851
                     /locus_tag="VW361_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU9744062.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGEVKMGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            14853..15596
                     /locus_tag="VW361_001001"
     CDS             14853..15596
                     /locus_tag="VW361_001001"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU9744063.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15607..17403
                     /gene="pepF"
                     /locus_tag="VW361_001002"
     CDS             15607..17403
                     /gene="pepF"
                     /locus_tag="VW361_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9744064.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNDLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            17649..17978
                     /locus_tag="VW361_001003"
     CDS             17649..17978
                     /locus_tag="VW361_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744065.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDGGLDKEIDKIGLPTLERSLGRLFMQLSCLTMPTS
                     NRFFIRN"
     gene            17933..18439
                     /locus_tag="VW361_001004"
                     /pseudo
     CDS             17933..18439
                     /locus_tag="VW361_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963306.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
     gene            18550..19218
                     /locus_tag="VW361_001005"
     CDS             18550..19218
                     /locus_tag="VW361_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU9744066.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEK"
     gene            complement(19243..19512)
                     /locus_tag="VW361_001006"
     CDS             complement(19243..19512)
                     /locus_tag="VW361_001006"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744067.1"
                     /translation="MLKAVFEVIDKTDEVSSKHCFEVADRTDEVSLKHCFEVADRTDE
                     VSLKHCFEVVDRTDVVSNHTYGKVKLTWFEEIFEEYHTKKPCSSR"
     gene            complement(19562..20095)
                     /gene="queF"
                     /locus_tag="VW361_001007"
     CDS             complement(19562..20095)
                     /gene="queF"
                     /locus_tag="VW361_001007"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU9744068.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWVMQHYETVEAVTFAYGQRHHLE
                     IQIAREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEDLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(20400..20714)
                     /gene="trxA"
                     /locus_tag="VW361_001008"
     CDS             complement(20400..20714)
                     /gene="trxA"
                     /locus_tag="VW361_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9744069.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(20731..20952)
                     /locus_tag="VW361_001009"
     CDS             complement(20731..20952)
                     /locus_tag="VW361_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9744070.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(21051..21431)
                     /locus_tag="VW361_001010"
     CDS             complement(21051..21431)
                     /locus_tag="VW361_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9744071.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(21574..22527)
                     /locus_tag="VW361_001011"
     CDS             complement(21574..22527)
                     /locus_tag="VW361_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9744072.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREKKIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(22595..23802)
                     /gene="sstT"
                     /locus_tag="VW361_001012"
                     /pseudo
     CDS             complement(22595..23802)
                     /gene="sstT"
                     /locus_tag="VW361_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            23941..24501
                     /locus_tag="VW361_001013"
     CDS             23941..24501
                     /locus_tag="VW361_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU9744073.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            24558..25456
                     /locus_tag="VW361_001014"
                     /pseudo
     CDS             24558..25456
                     /locus_tag="VW361_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
     gene            25408..25998
                     /locus_tag="VW361_001015"
     CDS             25408..25998
                     /locus_tag="VW361_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU9744074.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            26001..27107
                     /gene="yqeH"
                     /locus_tag="VW361_001016"
     CDS             26001..27107
                     /gene="yqeH"
                     /locus_tag="VW361_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU9744075.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSNALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            27322..27633
                     /gene="yhbY"
                     /locus_tag="VW361_001017"
     CDS             27322..27633
                     /gene="yhbY"
                     /locus_tag="VW361_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU9744076.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            27685..28314
                     /locus_tag="VW361_001018"
     CDS             27685..28314
                     /locus_tag="VW361_001018"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU9744077.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            28314..28907
                     /gene="yqeK"
                     /locus_tag="VW361_001019"
     CDS             28314..28907
                     /gene="yqeK"
                     /locus_tag="VW361_001019"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU9744078.1"
                     /translation="MAYQDYINCSREVLLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLALIDRHQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            28908..29408
                     /locus_tag="VW361_001020"
     CDS             28908..29408
                     /locus_tag="VW361_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9744079.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            29421..29774
                     /gene="rsfS"
                     /locus_tag="VW361_001021"
     CDS             29421..29774
                     /gene="rsfS"
                     /locus_tag="VW361_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU9744080.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            29877..30623
                     /locus_tag="VW361_001022"
     CDS             29877..30623
                     /locus_tag="VW361_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9744081.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFSMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            30633..31730
                     /locus_tag="VW361_001023"
     CDS             30633..31730
                     /locus_tag="VW361_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU9744082.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIAYLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARESDLPEGIHVLGFTEKGRQHLKYLKGQVSLVSRIGKEPWDV
                     MTQKADQIYQLGNPSIAEQNFGRVPIRIETN"
BASE COUNT         9675 a         5785 c         7061 g         9376 t
ORIGIN      
        1 atataatttt taaaattaaa aatataatct ttagacttga atttgattct gtattcacgc
       61 cctcaataga cggtaaaata agaaaattgt ttatatattg tctccgtagt gttattatac
      121 gaaataaaag attttaggaa aagtcgttat atcatgctat acctattctt tgtggtataa
      181 ttgcaagagg tttaatccga taatttataa agagagaaag atattcatga gagatttatt
      241 atctaaaaaa agtcataggc aattagaatt attagaatta ttatttgaac ataaacgttg
      301 gtttcatcgt tctgaactag cagagttatt aaattgtaca gaacgtgcag tcaaagatga
      361 tctatcccat gttaaatctg cttttcctga cttgattttt cattcttcta ctaatggtat
      421 acgcattatt aataccgatg atagtgatat tgaaatggtt taccatcatt tctttaaaca
      481 ttcaactcat ttttcgattt tagaattcat cttctttaat gaaggttgtc aagctgagag
      541 tatttgtaaa gaattttata tcagttcatc ttcgctctat cgtattatta gccaaatcaa
      601 taaagtgatt aaaaggcaat ttcaatttga agtcagtctg acccctgttc aaatcattgg
      661 aaatgagaga gacattcgtt acttttttgc acaatatttt tcagaaaaat attatttcct
      721 agaatggcca tttgaaaatt tttcatcaga gccactatct caattgttag aattggttta
      781 taaggaaaca agctttccaa tgaatttgtc aacgcataga atgctaaagt tgctcctagt
      841 tacgaaccta tatagaataa agtttggtca ttttatggaa gtagataaag attcttttaa
      901 cgaccaaagt ttggattttt taatgcaggc agaaggaata gaaggtgttg ctcagagttt
      961 tgaatcagaa tacaatatct ctttagatga agaagttgtt tgccaattat ttgtgtctta
     1021 ctttcaaaaa atgtttttca tagatgaaag tctctttatg aaatgcgtaa aaaaggatag
     1081 ttatgttgaa aaatcttacc atctattgag tgattttatt gatcagattt cagtcaagta
     1141 tcagattgaa atggagaata aggataatct gatttggcat ctgcataata ccgcacatct
     1201 gtatcgtcaa gagttgttta ctgagtttat tttatttgat caaaaaggga atacaatcag
     1261 gaactttcaa aatatttttc caaaatttgt ttcagatata aaaaaagagc tttctcacta
     1321 tttagagact cttgaggttt gttctagttc aatgatggta aatcatctat cttatacctt
     1381 catcactcat accaaacatt tggtgattaa tttgctacaa aatcagccta aactaaaggt
     1441 tttagttatg agtaattttg atcagtatca tgcaaaattc gttgcagaga cactttctta
     1501 ttactgtagc aataattttg aactggaagt ttggactgaa ttagaattat caaaggaatc
     1561 tttagaagat tcatcttatg atatcattat ttctaatttt attattcctc ctattgaaaa
     1621 taagagactc atctattcaa ataatataaa cacggtctca ctcatatatt tgttaaatgc
     1681 catgatgttt attcgattag atgagtaacc aaaaataaca aaaaaacgct atttcgcgtt
     1741 tgaactgtac ctcaaaagtt agacagaaaa aatctaattt ttggggtgtt tttgttaaga
     1801 aaagaccttc aatcatttaa gcaaaatgta catctagatt tatagccctc taaaactctt
     1861 gctttttttg tagaagatac aaaaaagcca taaaaccaag gcttttcctg ttttatgtag
     1921 atgtttacac atgaaaattg aagtattttc aaaagctaat tggagtgatt ttattcatga
     1981 tgggataaat gatctggcca aaaatgattg agaaatagtt gcttaaaaag catttgcatg
     2041 atactatata ttgaaaggag gtgataatat ggtagaacaa agaaaatcaa ttaccatgaa
     2101 agatgttgct ttagaagcag gagttagtgt tggaactgtt tcacgtgtaa ttaataaaga
     2161 aaaaggcatt aaagaagtaa ctttgaaaaa agtggaacaa gcgattaaaa ctttgaatta
     2221 cattccagat tactacgcta gaggaatgaa aaaaaatcga acagaaacga ttgcaatcat
     2281 tgtaccaagt atctggcatc ccttcttttc agaatttgct atgcatgtgg aaaatgaagt
     2341 ctataagaga aataacaaat tactcttatg ttctatcaat ggtacaaata gagagcaaga
     2401 ctatctggag atgttgcgtc ataataaagt tgatggagtg gttgccatta cctatagtcc
     2461 aattgaacat tacttgacgt caggaattcc ctttgttagt attgaccgca catactcaga
     2521 tattgccatt ccttgtgttt catcagataa tgatgcaggt ggaagagaag cagctaaaca
     2581 attaattagt aaaggatgtc agcatttagc ctttgtgggc ggacataata caaccattaa
     2641 tgaaaccaaa cgtcgtagaa tttcatttga aaagtatgtc caagagcata aaatacctct
     2701 tagtattttt gatttggatg agacagttac tgactattat ggaaagctag agagtttctt
     2761 ggaagaaaat tcttctatag atggaatttt tacaatcaac gattttacag ctttggatgt
     2821 gattgaaata ctaaaaaaaa atggcaaacg tattcctcat gatgtccaaa ttattggata
     2881 cgatggaatt aaaatggctg gagatagaga ttatctactt tcaactattg aacaaccatt
     2941 ggaagaaatg gcaaaagaag cggttcgtat tttgtttgat ataattgatg gaaagactgt
     3001 taatttgcag acaatcctac cagtaaaatt tgttgaagga aaaacaacaa aaaatgaaaa
     3061 taagtcttga cagaaagcgc tatcaatgat agaatgaatt cagataaaaa gatttatttt
     3121 taaaacaaaa atgaaacgtt tcaaaaagag aaatgaagag acagcgtcaa gcgctatctt
     3181 ttctagaaaa aaatgaaacg tttcaaaaag gaggttgcta tgaatagcaa agcgaagcaa
     3241 gtttctcttt gggaaagaat caagaaacaa aaactcttgt tattgatgac tgtccccggt
     3301 ttagttttaa cctttatctt taaatacatc cctatgtatg gggttttaat cgcatttaaa
     3361 gattacaatc ctttaaaagg aattttaggg agtgattgga ttggtttttc tgagtttaca
     3421 aaattcatat cctctcccaa ctttggtatc ttgttagcca acacattaaa attaagtatc
     3481 tatggtttat tgcttggctt tttaccacca atcattcttg ctattatgct caatcaactc
     3541 ttgagtgaaa aagtcaaaaa acgaattcag ctcattttat acgcaccaaa ctttatctca
     3601 gtcgttgtta ttgtcggtat gattttcctc ttcttttcag tgggaggacc aatcaacaat
     3661 tttctttcta tgtttggaat gaaggctgac ttcttgacaa atccagactt ctttagaccc
     3721 ttatacatct ttagtggtat ctggcaagga atgggctggg cttcaacgct ctacacggca
     3781 acattggtaa atgtagatcc agccttagta gaagcagccc gactggatgg agccaatatc
     3841 ttccaacgaa tctggcacat tgatattcca gctcttaagc ctattatggt tatccaattt
     3901 gttttagctg caggtggaat tatgaatgtc ggatatgaaa aagcattctt gatgcagaca
     3961 tcgttaaatt tgccaacttc tgaaattatc tcgacatatg tctataaagt tggtcttgta
     4021 tcaggagact attcttactc aacagcggtt ggtttgttta atgcagtgat taacgtagta
     4081 ttgcttgttg cagttaacca aatcgttaaa cgcatgaata atggtgaagg aatttaagga
     4141 gggaagtatg aaaaattcga ttatggatac aaaatttgat agacgtatct tactcttaaa
     4201 taaaatcatt attgtcttta tcgttttgat gactttgctt cctttacttt atatcgtcgt
     4261 agcatccttt atggatccta aggttctggt tagtagaggg attagcttta atccagccga
     4321 ttggactgta gaaggttatc agcgtgtatt cagtgaccaa tctattctaa gaggttttat
     4381 caattctcta ctatactctt ttggatttgc agctttaaca gtattgctat ctgtgtttac
     4441 agcttatcct ctttctaaga aagacttggt tggacgtcgt tggattaact acttcttgat
     4501 tgtgactatg ttctttggtg gtggtttagt cccaacttac ttgctcgtaa aagaattggg
     4561 aatgctcaat actccatggg ctatcattgt tccaggtgct gtcaacgttt ggaatattat
     4621 tcttgctagg gcctatttcc aaggattgcc tgaagaatta gttgaagctg ctgtcattga
     4681 tggtgcaaat gatttacaga ttttcttcaa aatcatgctt cctcttgcaa aaccaattat
     4741 gtttgttctc ttcctttatg cttttgtagg acagtggaac tcatactttg atgcaatgat
     4801 ttatatcaag gatccaaact tggaaccatt gcaacttgta cttcgtaaaa ttctcattca
     4861 gagccaacca ggtcaagaca tgattggagc acaagcggct atgaatgaaa tgaaacgttt
     4921 agctgaattg attaaatacg caactattgt catttccagc ttgccattga ttgttatgta
     4981 tccattcttc caaaaatact ttgataaagg aattatggct ggttcactta aaggataaaa
     5041 aaagaaaaaa taaaaggagt tttctcatga aattcaaaac attctcaaaa tcagcagttt
     5101 tgttgacagc tagtttagca gtacttgcag cctgtggctc aaaaaataca gcttcaagtc
     5161 cagattataa gttggaaggt gtaacattcc cgcttcaaga aaagaaaaca ttgaagttta
     5221 tgacagccag ttcaccgtta tctcctaaag acccaaatga aaagttaatt ttgcaacgtt
     5281 tggagaagga aactggcgtt catattgact ggaccaacta ccaatccgac tttgcagaaa
     5341 aacgtaactt ggatatttct agtggtgatt taccagatgc tatccacaac gacggagctt
     5401 cagatgtgga cttgatgaac tgggctaaaa aaggtgttat tattccagtt gaagatttga
     5461 ttgataaata catgccaaat cttaagaaaa ttttggatga gaaaccagag tacaaggcct
     5521 tgatgacagc acctgatggg cacatttact catttccatg gattgaagag cttggagatg
     5581 gtaaagagtc tattcacagt gtcaacgata tggcttggat taacaaagat tggcttaaga
     5641 aacttggtct tgaaatgcca aaaactactg atgatttgat taaagtccta gaagctttca
     5701 aaaacgggga tccaaatgga aatggagagg ctgatgaaat tccattttca tttattagtg
     5761 gtaacggaaa cgaagatttt aaattcctat ttgctgcatt tggtataggg gataacgatg
     5821 atcatttagt agtaggaaat gatggcaaag ttgacttcac agcagataac gataactata
     5881 aagaaggtgt caaatttatc cgtcaattgc aagaaaaagg cctgattgat aaagaagctt
     5941 tcgaacatga ttggaatagt tacattgcta aaggtcatga tcagaaattt ggtgtttact
     6001 ttacatggga taagaataat gttactggaa gtaacgaaag ttatgatgtt ttaccagtac
     6061 ttgctggacc aagtggtcaa aaacacgtag ctcgtacaaa cggtatggga tttgcacgtg
     6121 acaagatggt tattaccagt gtaaacaaaa acctagaatt gacagctaaa tggattgatg
     6181 cacaatacgc tccactccaa tctgtgcaaa ataactgggg aacttacgga gatgacaaac
     6241 aacaaaacat ctttgaattg gatcaagcgt caaatagtct aaaacactta ccactaaacg
     6301 gaactgcacc agcagaactt cgtcaaaaga ctgaagtagg aggaccacta gctatcctag
     6361 attcatacta tggtaaagta acaaccatgc ctgatgatgc caaatggcgt ttggatctta
     6421 tcaaagaata ttatgttcct tacatgagca atgtcaataa ctatccaaga gtctttatga
     6481 cacaggaaga tttggacaag attgcccata tcgaagcaga tatgaatgac tatatctacc
     6541 gtaaacgtgc tgaatggatt gtaaatggca atattgatac tgagtgggat gattacaaga
     6601 aagaacttga aaaatacgga ctttctgatt acctcgctat taaacaaaaa tactacgacc
     6661 aataccaagc aaacaaaaac tagaggttga ttatgggaga taagaaatac acagtagaaa
     6721 aagccaatcg ttttatagca gaaaataaac atctcgttaa tactcaatat aagcctgaag
     6781 aacatttttc agctgagatt ggttggatca atgatccaaa tggatttgtc tattttcgtg
     6841 gagaatacca tctcttttat caattctatc catatgatag tgtttggggg cctatgcact
     6901 ggggacatgc taaaagtaag gacttggtga cttgggagca cttgccagtg gcacttgctc
     6961 ctgaccaaga ttatgaccga aatggttgtt tctcaggctc tgccattgtc aaggatgatc
     7021 gcctctggct catgtacact ggacatatcg aagaagaaac cggtgtccgc caagtgcaaa
     7081 atatggtatt ttcagatgac gggattcact ttgaaaagat ttcccaaaat ccagttgcaa
     7141 ctggatcaga cttaccagat gagttgattg ctgctgattt ccgtgatcca aaactctttg
     7201 aaaaagatgg acgctattac tccgtagtag ctgccaaaca caaggataat gtgggctgta
     7261 tcgttctact agggtccgat aacctagtag aatggcagtt cgaatccatc tttttaaaag
     7321 ggggagaaca ccaaggtttt atgtgggaat gcccagatta cttcgagtta gatgggaaag
     7381 attgccttat tatgtcaccc atgcgttatc agcgtgaggg agactcatat cataacatca
     7441 actcatcgct tttgttcacg ggtaaggtag attggagaga aaaacgtttt atcccagaat
     7501 cagttcaaga aattgatcat ggccaagact tctatgcgcc tcaaacattg ttggacgatc
     7561 aaaatcgtcg tatcctgatt gcttggatgc agacatgggg gcgtaccctt ccaacccatg
     7621 accaagaaca caagtgggca tgtgccatga ctctacctag aattctaaga ttggaagatg
     7681 gcaaactaag acaattccct gttaaaaaag gccaatatca aatccaaata gataaagatt
     7741 gtcattacca cttaggaaat gatatagatt atcttgaatt tggttatgac agtaatgcgc
     7801 agcaagttta cattgatcgt agccatctta ttcaaaaaat tctaggtgaa gaagaacagg
     7861 acactagtcg acggtatgta gatattgaag ctaaagaatt ggaagttgtt ctagataaaa
     7921 attccatcga gatttttgtc aatcaaggtg aagcaagctt gactgcaact tattacttaa
     7981 cggtgccagc tgagctatca cgaattgatt aaaaattaag ttatttctcc taaagaaaaa
     8041 gttctctttc taaaatagtg gaaagaggac tttttgtgtt ttgggtatat aagcttagtt
     8101 tatggtattt gtaaaattgg tgttggatta tgatttaagc tagttttcta aagaatttga
     8161 aaaaaatttt atttaagcaa aaaaaccttg gttccaaggc ttttcctgtt gtatttagat
     8221 gccccctaca gggatcgaac ctgtgaccca cggattaaga gtccgctgct ctgccagctg
     8281 agctaaggag gcaaagaaaa aagctgtatt ggtgccgaaa cttcacggtt tgtattgaac
     8341 ccgcgcaatt aagcaggtgg gcaactcgct ctaactgaag ctgtttccgt gtgagacggc
     8401 ctacatgctg ttagaagact tttgtttccc taataataca aaaaatagtc ggtcaacact
     8461 taagtgtgaa gtcgtacacc acagcgtttc tatacttata tgataccact ttttcaaaaa
     8521 aaatcaagag gaaagtgcaa ttttttgaaa aggatttcag atttttcgca aacggtcgat
     8581 agcttccttt ctttgagcca aagcccgttc atatttacca gtatcttctg cttggaaata
     8641 gtgatgatta cgaatttttt ctggcagata gtcttgcttg acccaatttc caggatagtt
     8701 gtgtggatag agatagtctt gggcattccc cagttccttg cttccactgt agtgcccatc
     8761 acgtaggtgt cgcggaatag gcaagtgccc tgatgttttg aggtcagcaa gtgccttatc
     8821 catagctaca taggctgagt tggattttgg agaaagggcc aaatcaatca cgacattggc
     8881 aatgagaatg cgggcttctg ggaacccaat cttctgggca gcatccagag cagtcacggt
     8941 atgaatctgg gcctcaggat tggctaaacc gatatcttca taggcgataa tagtcaagcg
     9001 acgagcgaga ctaggcagat ccccagcctc aatcaagcgg gcagcatagt ggagactggc
     9061 atccacatct gagccacgga tagacttttg cagggcagat agaacatcat agtgaccgtc
     9121 tccatccttg tccatagtga tgtagcttct ctgaagacta ttttccatga tgtctaaggt
     9181 gatgtggcga atgccctcgt cattctcagg ggtagagaga acagccaagt ccagtgagtt
     9241 aaaggcagag cgaaggtctc cgtttgtaga ggttgcgatg aaatccagcg catcctcatc
     9301 tagttctatt ggaaaattaa aaccacgttc agggttactt agagctatct gcagggcctc
     9361 tttgacgtct tggttagaca gaggttccaa ctcaaaaatt tgaacacggc tacgaatggc
     9421 aggagtgacg gaaaagaaag gattttcagt cgttgctcca atcatgatga ccagtccact
     9481 ttccaagaga ggcaagagga agtcttgctt ggtcttatct agtcgatgaa tttcgtctag
     9541 caataggacg agaccgccag aaaatttagc ctcttcggcg atttcttgga gtcttttttt
     9601 actatcaact gtcgcattga aagttcgaaa ggcatacttg gtcgttccag cgatggcaga
     9661 ggcaatactg gttttgccga ttccaggagg gccatataga atcatggagg acaggcggtt
     9721 ggcttccacc atgcggcgga tgatttttcc aggtccgacc agatgctcct gaccgatgac
     9781 ctggtcgatg gttttagggc gcatgcgaag cgcgagattg tctggcatag cagtcctttc
     9841 taacgtggat ttgagtagaa tgactcatct actatatctt actatgtcca ttctagccta
     9901 ttagttgtga tatttcaatg gttttgtaat aatcagggag tgagatagaa tcttttttac
     9961 tatttaattt aatgaggaga ggtatcagca tgagagattt gattttcctt aaagctcaaa
    10021 ataggatagt tgagcctaaa gaagtggaag tgctgacttg agaaataata ttgctaaatg
    10081 tcattgtatg aactataatg aaaagagagg tgataagcaa tggaaatgat ggaccaagtc
    10141 aggaaatttt gatttttaca aaacaaattc gtcattggat tcttagtgat caagttattt
    10201 cagggaaaag aaaacttttc ttccgggaag atactccaaa agagatttta gatttgtacg
    10261 aaaacattaa atctaaactt gattttgctt accaagaagt tcattctaat aatgggttga
    10321 aaaaatatga aaaatagaat aattgatgtt tttgaagtag taaatcgcct ccttgtaata
    10381 actgttgaaa atcctgattt cgaagacttg agagttaatc atactcaatg aaaatcaaag
    10441 agcaaactag gaaactagcc gcaggctgta cttgagtacg gtaaggcgac gttgacgtgg
    10501 tttgaatttg attttcgaag agtatcagtt tgtaaaaatt ggagataaaa aatatagagt
    10561 acgcagtggt cctatgattc attcaactcc gcctcaatct gtcttagatc gagatacttt
    10621 tacaattgac tatacagatg atgaattgct cgataaagaa gcagttttta ctactcatta
    10681 gaaaaatagg tatgaataaa ttggcttccc ttagaaccac atctaggggc ttttatgtat
    10741 aatagaataa taagtatcac tcctttacaa tacgtgtaac acgtgttata atggtgttgt
    10801 caggaggtaa aagcgctatg cctatgacac aaaaagagat ggttaaactc cttacggccc
    10861 atggttggat aaagactaga ggcggtaaag gctcccatat taaaatggaa aagcaagggg
    10921 aaagacctat cacaatcctt catggtgagc tgaataagta cactgaaaga gggataagaa
    10981 agcaagctgg gttgtaaaat tcagcccctg ctttttgata tggaggtagt gaaatgttag
    11041 ttacgtatcc agctttattt tattatgacg acacagacgg aacagaagcg acttattttg
    11101 tccatttccc agattttgaa tactcagcta cacaaggaga ggggatttct gaggctttgg
    11161 ctatggggtc ggagtggcta gggataactg ttgcagattt gatagagagt gatggagagt
    11221 tacctcagcc atcagatatc aatagcttgt ctttaattga taatgatcct tttaaagatg
    11281 atgaagattt cgtgtcaacc tatgaccttg ataaatcttt tatttctatg gtatctgttg
    11341 atgtatcaga atacctagga agtcaggaac ccattaaaaa gactttgacc ataccaaaat
    11401 gggcagataa gttgggacga gaaatgggac ttaacttttc tcagactttg acagacgcta
    11461 ttgcagataa gaaagttcaa gcctaagatt aagcgtggta tcgtggtaat agtcaataaa
    11521 aaagcacgtc cacttgtgct agttactcgc ctattgattt tatagattta ttagcccttt
    11581 cgcgggcttt ttatattgat ttttatgaga aatgaagaaa tcagactttt aagaaaatca
    11641 ctgataccaa gggtttaaat gaggtaatat ggtataatta ggacataaaa taattttgtg
    11701 gtaagatggt agtatctatt ttagcatatt tccgagcaat cggggcgatt aaagagtcgc
    11761 atagaaagag gacaaaatgg caacatacgg atttttagat gttttagagg aagagttgga
    11821 caagaacttt ccctttgact ttgagattag ctgggacaaa cgcaaccatg cggtagaagt
    11881 gagttttcta ttggaagcgc aaaatgctgc aggtgtggag atggtggatg aagacggaga
    11941 ggtttcatca gatgacattc tttttgagga agcggtcctt ttctacaatc ctgccaagtc
    12001 aacagtcaat gaggaagact atttgactgt tattccttac ctgcctaaaa aaggattttc
    12061 ccgtgaattt ttagcttatt tttcgctttt ccttaaagat actgctgagg ttgggctaga
    12121 tgtcctcatg gactttttgg aagacccaga agcagaggaa tttatcatgg aatggaacca
    12181 agaagtcttt gaagaaggaa aagttggctt ggaagaggga gaattttatc cttatccgag
    12241 atactaggag ttggttggag gtgttatgaa gaaaattggg acttatttgg tttatgtgct
    12301 agctgttgtc tttattatgc tagcttttgc ttgtggaaca atcgcatttg cagagttggg
    12361 gtattccgca gttttagcct ttacttttgg ttatgccttc gctcttctaa gcatgtattt
    12421 aatttttatt cttcatgagc tgggtcatgc tttttgtggc tacttgacag gctatcggct
    12481 ggtggctttt ggattaggac attttatttt gaccaaaaag tcaggcaggt ttcatcttag
    12541 tagaacagcc attctgaaaa atgttggtgc tcaatacatt ggtttaaaag aggatgaaag
    12601 cgatcaaaga atcatcctga tgctttcagg aggcttgatg gttcatctcg gcttgatatt
    12661 attggcgata gtgtttggat ttttgacaag aagctggtat tttgcaggga cttggatttt
    12721 tcttaattta tctttcttcc taaataacat tttgccagtc gacatcaccg atggagcaaa
    12781 aatttgggaa ttactacaac accctgaaaa taccaaatac gcctacctgg tattgagaca
    12841 ttctgctcaa actttgctgg ctcctcaaga atatgatttg aaagactttg ttcaagcagt
    12901 tcctgaggat gcacgaggga gttttgcgga tggtgtatta ggtatgcaag gtgaagtttc
    12961 cattttggaa gggaaggaag aagtagctaa acagcagttt caagcattac ttgagagggc
    13021 aactactccg atgatgcaga cagttgccca actatccctg cttcatatcg ccttgttgga
    13081 aggagatttt gagcaagcgg agcaatatgc tagtattcga caggtcaaat cgtttctgtc
    13141 tctcaaactg tccaatcttc aagtgataca agcctggtat caattaaagg tgaagaaaga
    13201 tgtagatcga actcgtaagg ctctcaagat tgctagacag aaaatggata gtagtcgaat
    13261 gttgagggac gagaaacgct attatgaaaa cttgttagcc gagctggaaa aggaaatgtt
    13321 agaaggaact gaagatggaa ctagaaattt ctggtttccc aggctgtaag attgctttgt
    13381 tttgtgggga taagctcttg actatcttac gtgatgataa ggcaagtatt ccctgggcca
    13441 atatgtggga actgccaggt ggtggacgtg aaggtgatga aagtcctttt gagtgtgtag
    13501 cgcgtgaagt ttatgaagaa ctgggcattc atctgactga agattgtctg ctttggagta
    13561 aggtttaccc aagtatgctt tttgcagaca aacagtccgt ttttctagtt ggtcagttga
    13621 cacagaacca gtttgacagt atcgtatttg gagatgaagg acagggctat cagctgatga
    13681 atgttgagga atttcttagt tccagtcaag ttgtgcctca gttgcaagag agattaaaag
    13741 attatttaaa agtaagtgat tagaaaggat ggttcagtta aatttctaaa ctgaacccgc
    13801 cctaaacact gtgccaaaaa gataaacttc tcttagacac aagcgtcttc agagaatttc
    13861 ctattttggt tttgtgtttt acgggcttgg tatcttaata atggaaacat ggcaagagtt
    13921 aaaagttaca gtgaagcgtg agggagagga gttggtttcc aatctcttga ttgagctggg
    13981 agcgcaagga gtcgcgattg aagacagcat ggactatatg ggaaatgtgg atcgttttgg
    14041 cgagattttc ccagaggtgg agcagcaaga agaaatcgta gtgacagcct actaccctga
    14101 cacggtggat gtgacagtgg ttgaggcgga cttgcaggct cgcttagcag aattgacgga
    14161 ttttatggat ttgggtgaag tcaagatggg gacgactgcc ttggctgagg aagactgggc
    14221 agacaactgg aagaaatact atgagccagc tcgtatcact catgatttga ccatcgttcc
    14281 ctcttggaca gactatgagg cgactgcggg agaaaaaatt atcaagctag atcctgggat
    14341 ggcttttggt actgggaccc atccaactac caagatgagc ctctttgcct tggaacaggt
    14401 tcttcgtggt ggcgagacag tgctagatgt ggggactggt tcaggggttc tctccattgc
    14461 tagctcgcta cttggtgcca aggaaatctt cgcctatgac ctggatgatg tggcggttcg
    14521 tgttgctcag gaaaatattg aacttaaccc tggaatggaa aatatccacg ttgctgctgg
    14581 agacttgctt aagggtgttg agattgaggc agatgtgatt gtagctaata tcttggcgga
    14641 tattctcatt catctgacag acgatgccta tcgtttggtc aaggatgaag gctacctgat
    14701 catgagtggc attatcaagg acaagtggga catggtgcgc gagtcggctg agtcagctgg
    14761 atttttcctt gaaacccaca tggttcaagg ggaatggaat acctgtgtct ttaagaaaac
    14821 caaggatatc tctggtgtga ttggaggcta gcatgcagca gtattttgta aaaggcagtg
    14881 ctatctctcc tgtcactatc gaggacaagg aaaccagtaa gcatatgttt caggttatgc
    14941 gcttgaaaga agaggatgag gttaccttag tctttgatga tggcatcaag cgcttggcgc
    15001 gcgtgctgga tatggaaaat cgtcagtttg agttggtcca agaattaaat gacaatgtgg
    15061 aactaccagt ccaagtgacc atcgcatctg gatttcccaa gggagacaag ctggagttca
    15121 tcgctcaaaa agtaaccgaa ctgggtgcta gccaaatctg ggcctttcct gcagactggt
    15181 cagttgccaa gtgggatggc aagaaattgg gtaaaaaagt tgaaaaacta gaaaaaattg
    15241 cccttggagc agccgagcaa agcaagcgta atattgtacc aagtattaaa cttttcgaga
    15301 aaaaagcaga ttttctagct cagctggacc agtttgactt tatcatagta gcctatgaag
    15361 aatcagctaa agaaggagaa gccgctgcgc ttctgcaagc agtcactggt cttgaaacag
    15421 gagccaaact gctctttatc tttggtccag aaggcggtct ctcacctgca gaaatcgaaa
    15481 gttttgaagc taagggagcc gttttggtag gcctaggtcc tcgtattttg cgagcagaaa
    15541 cagcaccgct ttacgcctta tcagccctta gtgttttagt agaattagag aaataagagg
    15601 aagaaaatgg aacaaaaaca ccgttcagaa tttccagaga aggaactctg ggacttaaca
    15661 gccctatacc aagaccgtga ggatttcttg cgtgcaatcg agaaagctcg cgaagacatc
    15721 aaccagttta gccgtgatta caagggcaat cttcacactt ttgaggattt cgagaaggcc
    15781 tttgcggaat tggaacagat ctacattcag atgagccata ttggcaacta tgcttttatg
    15841 cctcagacga cggactatag caatgacgaa tttgccaata ttgcccaagc tgggatggaa
    15901 tttgaaacag atgccagcgt agccttgacc ttctttgacg atgccttggt ggcagcagac
    15961 gaggaagtct tggaccgttt gggtgaattg cctcacttga cggcagctat tcgtcaggcc
    16021 aaaatcaaaa aagcccacta tctaggggct gatgtggaga aggccttgac caatctcggt
    16081 gaagttttct acagtccgca ggacatttat actaagatgc gagctgggga ttttgaaatg
    16141 gctgactttg aagcccatgg caagacctac aaaaacagct ttgtcaccta tgagaatttc
    16201 taccaaaatc acgaggatgc tgaggttcgt gagaaatcct tccgttcctt ctcagaggga
    16261 cttcgtaagc accaaaatac ggctgcagca gcctatctgg ctcaggtcaa gtctgaaaaa
    16321 ctcttggctg atatgaaggg atatgactct gtctttgact atcttctagc tgaacaagaa
    16381 gtggaccgtg tcatgtttga ccgccagatt gaccttatca tgaaggactt tgcaccagtc
    16441 gctcagagat acctcaagca tgttgccaag gtaaatgatc ttgaaaagat gacctttgca
    16501 gactggaaat tggacttgga cagcgccctg aatcctgaag tgactattga cgatgcctat
    16561 gatttggtca tgaagtcggt agaacctttg gggcaagaat attgtcagga agttgctcgt
    16621 taccaagaag agcgctgggt ggactttgct gctaacagtg gcaaggattc cggtggttat
    16681 gcggcggacc catatcgcgt acacccttat gtactcatga gctggacagg ccgtttgagc
    16741 gatgtctata ccttgattca tgaaatcgga cattctggtc aattcatctt ttcagacaat
    16801 caccaaagct atttcaacgc ccacatgtcg acctattatg ttgaagcacc gtcaaccttc
    16861 aatgaattgc tactcagtga ttacttagag aaccagtcta atgacccacg tcaaaaacgc
    16921 ttcgctctgg ctcatcgctt gacagacacc tacttccata atttcatcac ccacctcttg
    16981 gaagccgcct tccagcgtaa ggtgtataca ttgattgaag aaggggagac ctttggagca
    17041 agcaagctca acagcattat gaaggaagtt ttgacagatt tttggggcga tgccattgaa
    17101 atcgacgacg atgcaactct gacttggatg cgccaagctc actactatat gggcttgtat
    17161 agttacactt actcagcagg actagttatc tcgactgctg gttaccttca tctaaaacat
    17221 tctgaaactg gagctgaaga ctggctcaat ctcctcaaat caggtggtag caagacacca
    17281 cttgagtcag ccatgattat cggtgctgat atttcaacag acaaaccact ccgtgatacc
    17341 atccaattct tgtctgacac agttgaccag attatctcct atagtgctga gttgggagag
    17401 taggggaata gaaaaatttt ttagaatgat gtttatgggc ttgttaagcg tcattctatt
    17461 tgtcttagtt gtagctattt tcaaaaatgt cgttgaaggt cgtgatgtta aatttgaact
    17521 tactgtagaa ctggtattga tagttattta cgtcatttta tatcagattg tatttaattg
    17581 agaattcaat attgagtcat ttaagactgc ctttttgaac agttgctaga aatgtagagg
    17641 tattgaccat gtatcaagat ttactaagaa aaatagcaga agaaaaacca aattataacc
    17701 aggaggaaat ccagtggttg cttgatcatt tgggagatcc ttctccagaa attcgtgatg
    17761 accttgtttt tacaagcttt gctagaggga ttcaggaaga gctatttaca caggagcaat
    17821 ttcatttcat tgctgaaggg gtttcatctg atggagggtt agataaagag attgataaga
    17881 taggcctgcc aacacttgaa cgttctttag ggcgcttatt tatgcaactc tcttgtctga
    17941 cgatgccaac cagcaatcgg ttttttatca ggaattaaat gcaggatttc gtaatgacct
    18001 ttcaaatcaa ggcttgcact atctttcaaa agaaaaggat acaacaggtt tctcaagtca
    18061 gtatggttgg gttcacgctt ttgcacatgg agccgattta ctgacagagg tggtttgtca
    18121 tccagacttt cctaaaaaca gagttcatga agtatttgat atacttggcc aactatttaa
    18181 aaggatgtcg attcgcttta cagatgatga ggattggcgt ttagcaagag tgatctatga
    18241 acctatttta taagggaagt tggagcaaga acaagtagct tcttggataa aaactgttga
    18301 ttttccgata gaagaaaggg aggattttta caaattttcc aactttagat cctgtctggt
    18361 ggaagtctat gtccaacttg accagagaaa tagtttacaa gatgagttga aagaagctat
    18421 ccagtctttt caatactaga gattagctaa tagttctatg attttcaaaa aatttccaat
    18481 caattttctt gaaacccttt cctacttttg atagactagt atctagtttt tgaaaaaagg
    18541 agaaagaaaa tgaaaaaatt tgttgctgag ttaatcggta cgttcatgct tgtgttcgtt
    18601 gggacaggag ctgttgtttt tggaaatggt cttgatggcc ttggtcacct tggaatcgcc
    18661 tttgcctttg gtttggcaat cgtggtggca gcctactcaa tcggaactgt ttcaggtgct
    18721 cacttgaacc cggctgtttc gattgctatg tttgtaaaca aacgtttgtc atcttcagaa
    18781 cttgtaaact acatccttgg tcaggttgtt ggagctttca tcgcttctgg cgcagtcttc
    18841 ttcctcttgg ctaattcagg tatgtcaact gctagtcttg gtgaaaatgc cttggcaaac
    18901 ggtgtcactg tctttggtgg tttcttgttt gaagtcattg caactttctt gtttgtctta
    18961 gttattatga ctgtgacttc agaaagtaag ggcaatggcg cgattgctgg tttggtaatc
    19021 ggtttgtcat tgatggcgat gattcttgtc ggattgaaga ttactggact ttcagtaaac
    19081 ccagctcgta gcttggcacc agctgtcttg gtaggcggcg cagcccttca acaagtttgg
    19141 attttcatcc ttgcaccaat cgctggtgga gttcttgcag cccttgttgc aaaaaatttc
    19201 cttggaacag aaaaataatt gaaactcaaa aagccttgct cctcatcttg aggaacaggg
    19261 ctttttcgta tgatactctt cgaaaatctc ttcaaaccac gtcagcttta ccttgccgta
    19321 ggtatggtta ctgactacgt cagttctatc cacaacctca aaacagtgtt ttaagctgac
    19381 ttcgtcagtt ctatctgcaa cctcaaaaca gtgttttaag ctgacttcgt cagttctatc
    19441 tgcaacctca aaacagtgtt ttgagctgac ttcgtcagtc ttatctataa cctcaaacac
    19501 tgctttgagc aacctgcggc taacttccta gtttgctctt tgattttcat tgagtatgac
    19561 tttagcggtt gtcaattttc tctggataaa ggtcgtgttg gaagaggcgt tgttctgcca
    19621 agtcctcata cttagttcct tgcttaccgt agttgtagta ggggtcgatt gaaatgccac
    19681 cgcgcggagt gaattttccc cagacttcta aatagcgagg gtctagcaag ttgaccaagt
    19741 ctttcccgat ggtgttgata cagttttcgt ggaaatctcc gtgatttcgg tagctaaata
    19801 gatatagttt gagggatttt gactcgacac agagcttgtc aggaatgtag gaaatatgaa
    19861 tcgtcgcaaa gtctggctga gcagtgattt gtcccagcag agacatatcg aggatatggt
    19921 gacgaatgcc ctgttcctta gcgatttctc tagcaatttg aatttcgagg tgatgacgtt
    19981 ggccgtaggc aaaggtgaca gcttcgactg tttcatagtg ttgcataacc cagaaaaggc
    20041 aggttgttga atcttgacca ccactaaaga cgaccaaggc tgattgacgt ttcatagtac
    20101 tccttccaaa atgggaaatg ttcagagcat gcaaaaagct cctattaggg agctaaaaaa
    20161 taccaaatcg agttttttta gcgatggcat atcccaaaca tcgtaatatt ctacttatat
    20221 agtaaaatga aataagaaca ggacaaatcg atcaggacag ttaaatcgat ttctaacaat
    20281 gttttagaag tagaggtgta ctattctagt ttcaatctac tatagtctag catatttttt
    20341 gaaaaatggc aaagggcaag aaaaaagaga ccaaagaaag tacttggtct ctcgtttgat
    20401 tagctcaatt cagcaatgat ggccttgatt tgttctgctg tgtgaacacc tgcaacttgt
    20461 ttgacaactt ggccgtcttt tttgaagaga agagttggaa tagacatgat tccaaaagca
    20521 cgagctgtgt ttggattttc atcaacgtcc attttaacga ttttcaagac atcttctgaa
    20581 agttcttcag acaatttgtc caagattgga ccttgcatac gacatggacc acaccaagtt
    20641 gcccagaagt ctactaagac caaaccatct tttgtttctt gttcgaatgt tgcatctgta
    20701 attgcttttg ccattgtatt tctccttttt ttagttatat tggcttaaat cttgtttcat
    20761 gagatagaag aagatatctc cataagtccc atggtagtcc aaattatgac ccttgtaagt
    20821 taatttttgg acagggtagt agtctgcgac gccgataagg caagcttgtt gcgaacgttc
    20881 aaagtcttca taagactcga aagtcacagt tctttcgttc ttgctggcat ctatataggt
    20941 aatttcaatc atatttaaaa ctcctttgtt taatgctaac tttattttac tccttataaa
    21001 agagaatgtc aagaaaaatg attgcgcacg caactttttt taaaatcatc ttaaatcaag
    21061 aaatccaaac ctgcttccaa gctttcttcg acagtctttt gtagcgaggc cagtgtcttt
    21121 tgcccatcat ttgtcaggca gataaaacta gagcgtctat cttgatggca acacatgcga
    21181 ctgagtagac cgcaattttt agcttccaag cgagccacca tcctagaaac tgcgctcggg
    21241 ctcagatgaa gtttatctgg caggtcaatc tggcgtagag atttttcttc agccaagtcc
    21301 agatagtaga gcaggtagaa ctctttcaag gtcagacttt gctcgctctg ttgggcaatg
    21361 gtctcttcca agagactttc aatttctttc tgacgccgat tgaagtcaaa ccatttttcc
    21421 aaataggtca tagtgtctcc tttcttttta gagtcataaa tagaagaaag tccattaacg
    21481 ggcagtctct gcgtcacaag atgattgcgc atgcaataat tatactactt ttcaagaatg
    21541 ctggcaagct ctgtttttta gtggttttat tttttactgt ctatattttt ggtaaaaatc
    21601 aacttttact tggatgaagg ttttggcttc acgtaggagt tgaagaaggg tggcgcgggt
    21661 ttcaaactct tctcttgtct tgggcagact gcggttccgg aagacttcca gataacgttc
    21721 aatttcatct agcaaatcag aagcaggatt ggtctggctc agttgacctg caatttttga
    21781 aaagagttgc gctaagatca ggctttcact ggcggcaagg tgacaagtgt taatctgttg
    21841 ggccatgttt ctcaggatac gactttgtcg ttgtctcatc tcaaagtagt ggatatggta
    21901 gtcggtctgg tgaaagaggt ggtcagagtg atccaaatag accagtctga gggcttcttt
    21961 caaaagcgtg tctaattctg ctaccagctg tgctcggttg cgtccgtctc ctctggataa
    22021 atagtatttg aagcgctgga ggatatcttt taacttttct tccaccagcg tgtggtagtg
    22081 ctggattttc ttttctcgtg aaggcatgta gagattgacc agtaaagcaa atcctgtacc
    22141 gatagcaaag agaaggaatt cattgactag aaggtctgga gaggttgact cttgaaccaa
    22201 gagatggcta accaaaacag tgcttggtgt gataccaatt tcccagccca tcttgtaggc
    22261 taaaggaacg tagaaggcca gatagaggcc gagactccag atatgaaatc cgctcaaatg
    22321 aaaagctaga acaccgatag ccagagctag aagcatagaa aaaagacgat tgcgagccag
    22381 ttttaaagta cttctacgcg tatcagatag gctcaagaga gcgataattc cagccgaaac
    22441 tgctgacgaa agattgagaa aataagcaag caggcaggca agacaggtag ctaagatgag
    22501 cttggtcgta cgttggctaa tagacataag aatttcctaa taagttagaa taaaagcgta
    22561 aaagacaaga catgagcagg cttgccttga tgagttattt tttacgggtt gctgcgtatt
    22621 cggcaacggc ggtaaagagg acatctgtag aagagttaag ggctgtttca catgagtctt
    22681 agatgacacc aatcacaaaa ccaaccccaa caacttgtat ggcaatatcg ttagaaatac
    22741 cgaaaaggct acaagcaact gggataagaa ggagggaacc tctggcaata cctgaagcac
    22801 cacaggctaa gatagctgct accacactga ggacaaaggc tgtggcaaag tcaacaggaa
    22861 ttccaagagt gttaactgca gcaagggtca aaaggttaat ggtaatcgct actccagcca
    22921 tattgatagt agaaccgagt gggatagaaa cagaataggt atctgggttg agtccaaggt
    22981 catggcagag tttcatgttg acaggaatgt tagccgcaga actacgagtg aaaaaggctg
    23041 tcacaccgct gacacggagg cagttccaaa ctagagggta aggattgcgt ctcataaaga
    23101 agaaggcaat caaagggtga ccacaagggc aacaaaaagc atagtcgtta ctaatagaac
    23161 caataaaata ccgtagttgg taaggcttcc gactcccttg tcagaaatgg ttttaaaaac
    23221 aagaccaagg cttccaaatg gagccagatt gatgatccat tcgacaattt tagaagtcac
    23281 gtcagcgata gtttttagca attctttact atttttactg gcttctctca tagcgattcc
    23341 aaaaatgact gcccaagata agattctaat atagttagca gtaaacaggg cgttgactgg
    23401 gctgtcaacc agtttgagca agaggttgct gagaacctgc ccaaccccat ctggtggtgc
    23461 aatttcagta ttggcactat ttagggtaat ttcaataggg acgatgaaac ttgctagtac
    23521 agctacaaga gcagcggcga aagtccctat cataggatat acaagaaaac aacagttttc
    23581 atattgctat cttgtccctt ttgatgttgg aaagggcatt ggcaacgagg gcaaagacta
    23641 ggataggagc aacagctttt agacctccaa cgaataaatc cccgagtagc ccaatccctg
    23701 agagattagg aagggtcagt cctaggattc cccacaaagc ataccaatca agatacgctt
    23761 gacaaggctt gccttattcc aagcatgaat gattcttttc ataataatct cctttttgtg
    23821 tagtgattat gattatagta taaatgatag acaaaatcaa gaattttctg tctatttttt
    23881 gaatatttat ggagaatgag actgatgaaa atatggtata atgaaataaa ggagttttat
    23941 atgcaaaaat ttattcaggc ttatattgaa aagctagatg tgacaaccat tatcgagaat
    24001 attctaacca aggtcatttc tcttttactg cttttgattg tattttatat tgctaaaaaa
    24061 atgcttcata ccatggtgca gagaattgtc aaaccttctc taaaaatgtc tcgtcatgat
    24121 gtcggacgcc aaaaaaccat ctcacgttta ctagaaaatg tgtttaatta tacgctatat
    24181 ttctttttac tctactgcat tttgtcgatt ttaggtttgc cagtttctag tttgctggct
    24241 ggagctggta ttgctggggt agcgattggt atgggagccc aaggctttct gtctgatgtc
    24301 atcaatggct ttttcatcct ctttgaacgt caactggatg tgggagatga ggtcgttctg
    24361 acaaatggac cgattactgt atcgggtaag gttgtcagtg tgggaattcg tacgacacag
    24421 cttcgtagcg aggagcaagc ccttcacttt gtccctaacc gaaatatcac agttgttagc
    24481 aatttctcac gcacagacta gacctgttat tttaagtaat ttgtggtaca atagagggag
    24541 tttaataagg agaaaagatg gttttagaaa agcagttggg caatggttgt acctggatag
    24601 acctagacct aggaaagttg aataaactag aagacctttc tgaaatttac ggtttggaca
    24661 aggaaaccat tgaatacgca ctggatagaa acgagcgcgc ccacatggac taccaccgtg
    24721 aaagtgggac ggttaccttt atctataatg tcctagacgt aaaaaaggac aaggcctact
    24781 atgagacttt tcccatgacc tttattgtcg agcatcgtcg cctgattacc attagtaata
    24841 ccaagaacgc ctatgtcatt gaacagatga ctcgttatct ggagagccat gacacgcttt
    24901 cgatttataa gtttctcttt gccagtctgg aaatcatcag caatgcctac tatcctgtca
    24961 ttgagcagat ggacaagagt agggatgagg tcaatgacct cttgcgccag cgaactacca
    25021 agaaaaacct ctttgccctg tctgatttgg agactggtat ggtttatcta acggcagctg
    25081 ccaaacaaaa tcggattttg ttagagcata ttcaaggtca tgccttgtat cgtagttttg
    25141 atgagattga gagagaacag tttgatgatg ccatgattga ggctcatcag ctggtatcca
    25201 tgacagacct aatctctcag attttacagc agctttcagc ctcttacaac aatattctaa
    25261 acaataatct gaatgacaat ttgacaacct tgactatcat ttcagtcttg ctagctgttt
    25321 tggcagtcgt gacaggcttt ttcggaatga atgttccctt gcctttaacc atgcttggct
    25381 ctatatcagt ttggctagtg caggtttgtg gattgtttta tccttgttac taaggaaaat
    25441 tgcgaaaaaa agttaagaaa aggagccaga atggcgattg aaaattatat accagatttt
    25501 gctgtggaag cagtctatga tctgacagtc ccaagcctgc aggcgcaggg aatcaaggct
    25561 gttttggtcg atttggataa taccctcatt gcttggaaca accctgatgg aacgccagag
    25621 atgaagcaat ggctacatga ccttcgggac gcgggtattg gcattatcgt agtgtcaaat
    25681 aacaccaaaa aacgcgttca acgagcagtt gagaaatttg ggattgatta cgtttactgg
    25741 gccttgaagc ccttcacatt tggtattgac cgtgctatga aggaattcca ctatgacaaa
    25801 aaggaagtgg tcatggttgg tgaccagctc atgacagata tacgagcagc ccaccgtgca
    25861 gggattcggt caattttagt caaacccttg gtccaacatg actcaatcaa aacgcagatt
    25921 aaccgaactc gtgagcgtcg tgttatgaga aaaatcactg aaaagtacgg accgattaca
    25981 tataaaaaag gaatttaact atggaagaaa ttctctgtat tggttgtgga gcaaccattc
    26041 agacgacaga taaagctggt cttggtttta ccccccagtc ggcacttgaa aaaggtttgg
    26101 agactggcga agtctattgc caacgctgtt tccgtctccg ccactacaat gaaatcacag
    26161 atgtccagtt gacgaacgat gatttcctca agctcttgca cgaggtggga gacagtaatg
    26221 ccttagtggt caatgtcatt gatatctttg attttaatgg atctgtcatc ccaggtttac
    26281 cacgtttcgt ctcgggcaat gatgtcctct tggtaggaaa taaaaaagat atccttccta
    26341 agtcagttaa gtctggtaag attagccagt ggctcatgaa acgtgcccat gaagaaggtc
    26401 ttcgtccagt cgatgtggtc ctaacttcag cacaaaataa acatgccatt aaggaagtca
    26461 ttgacaagat tgaacactac cgtaagggcc gcgatgtcta tgtggtcggt gtgaccaacg
    26521 ttggaaaatc aactctaatc aatgctatta tccaagaaat cacgggtgat cagaatgtca
    26581 tcactacttc acgcttccca gggacaacct tggacaaaat agagattccg cttgacgacg
    26641 gatcttatat ttacgatacg ccgggaatta tccaccgcca ccagatggct cactacttga
    26701 cggccaaaaa cctcaagtat gtcagtccta aaaaggaaat caagcctaag acctatcagc
    26761 ttaatcctga gcaaacccta tttttaggtg gtttgggacg ctttgacttt atagcaggag
    26821 aaaagcaagg atttactgct ttctttgata atgaactcaa actccatcgt agcaagcttg
    26881 aaggagctag tgctttctac gataagcacc tgggaactct tctgacacca ccaaatagca
    26941 aggaaaaaga agatttccca aggctagtcc agcatgtctt taccattaaa gataagacag
    27001 acctagtcat ctcaggccta ggctggattc gtgtaacagg catagcaaaa gtcgccgtct
    27061 gggcaccaga aggcgtcgcc gtcgtcacac gaaaagcaat tatttaagca cagaaaggaa
    27121 agggttgtct gaatttgggc gagcaaggcg agccccatag agaatacttt tcgctgtggt
    27181 gtaagttggt acaagtgatt gtaccaactg cggaaaattt gagaccttag gctcaaattt
    27241 tagtcatgaa agtccgaagg actttgctga cgtccgtcac cacttcagaa aagtataaaa
    27301 agaaactctt ttaaagaaat tatgtcatta acatcaaaac aacgtgcctt cctcaacagc
    27361 caggcacaca ccctcaaacc tatcatccaa atcgggaaaa atggactcaa cgaccaaatc
    27421 aaaaccagcg tccgtcaagc tcttgatgcg cgtgaattaa tcaaggttac tctcttacaa
    27481 aacacagatg aaaacatcca cgaagtagct gaaattttgg aagaagaaat cggtgtggat
    27541 acagtccaaa aaataggacg catcttgatt ttgtttaaac aatctagcaa gaaagaaaat
    27601 cgcaagattt ctaagaaagt caaagaaatc taagaccgaa actccaaata actgttttta
    27661 tagagaaata aaggggacta gcctatgaca atcgaactat tgactccctt taccaaggta
    27721 gagttggagc cagaaatcaa ggagaaaaaa cgcaaacaag ttgggatttt aggggggaat
    27781 tttaaccctg ttcacaatgc ccatctcatt gttgcggatc aagtacggca acagttggga
    27841 ctggatcaag ttctgctcat gcctgaatac caacctcctc acgttgataa aaaggaaacc
    27901 atccctgaac accatcgtct caagatgctt gagttggcaa ttgaggggat tgacggccta
    27961 gtcattgaaa ccattgagtt ggagcgcaag ggtatttcct acacctacga caccatgaaa
    28021 atcttgacag agcaacatcc agatacggat tattacttta tcatcggcgc cgacatggtt
    28081 gactatctgc ctaagtggta ccgaattgat gaactggttg acatggttca gtttgtgggg
    28141 gttcagcgtc cacgctacaa ggcagggact tcctatccag ttatctgggt ggacgtaccg
    28201 ctcatggata tctcgtccag catggtgcgg gacttcattg cccaaggtcg gaaacccaac
    28261 tttctcctac ctcagcctgt gctagactat atcgagaagg aagggctcta ctgatggcct
    28321 atcaagacta tatcaactgc tctcgtgagg ttttgttgga aaaaatggca gagcttctac
    28381 ctgagaaacg tctaacccat tgtctaggtg tggagcgtgc cgctatggaa ttagctcagc
    28441 gctttggtgt agatgttgag aaagcaagtc tagcaggtct tcttcatgac tatgctaaaa
    28501 agttgtcaga tcaggaattt ctagccttga ttgaccgtca ccagctagac cctgacctca
    28561 aaaactgggg caataatgtc tggcatggta tggtcggaat ttacaaaatt caggaagatt
    28621 tggatttgca tgattctgaa attctgcgag ccattgaagt ccatacagtc ggtgctggtc
    28681 aaatgacaga cctagataag gtcatctacg tcgcagacta tatcgagcac aatcgagcct
    28741 ttcctggagt agatgtggcg cgtgagattg caagtctatc gctcaataag gcggtggcct
    28801 acgaaacagc tcgtaccgtg gagtatctag ctcatcaggg attccccatc tatccccaaa
    28861 cccttgaaac ctataacgcc tttgtgcact atttgaaaga gaactaaatg aagacggctt
    28921 ttataatcat tgatgttcag aatgttttag tagaaactgg gttccagaca aaaagtctat
    28981 tgggaaaaat ttcttattta caaaaccagg ctagaagcaa gaatattgaa attatctatg
    29041 ttcaacatat tgagaactct gaagctcaaa catcagaaga ttggcagtta tctgcgcttt
    29101 taaatcgaaa acctgctgaa aaggtctttc agaagaagta taacagtatt ttcaaagaaa
    29161 ctggcttaaa agaatacttg gataaacagg ggattgaaaa attagtttta tgtggtatgc
    29221 agacagaata ttgtgtggat acctctgtca aggttgcctt tgaatatggc tatcagctta
    29281 ttgttccaga aggtgctgtc acaacctttg atggggatga cattccagca gaaacgatta
    29341 atgaatttta tgaggacatt tgggaggagc actttgcaga tgtcctagat tacaaacata
    29401 ttttctaaaa agaggattaa atgaacgaaa aagaattact agaactagtc gtgaaagcgg
    29461 ctgatgagaa acgtgcggag gatatcctcg cacttgatgt acaagatttg actagtgtga
    29521 cggactactt tgtcatcact agctcaatga atagccgtca gttggacgct atcgcagcta
    29581 atatccgtga aaaagtagct caagcaggct ttaaaggtag ccatgtcgaa ggcgatgcag
    29641 ctggaggctg ggtcttactg gacctcggtg ctgttgtcgt gcatatcttt tcagaagaaa
    29701 tgcgtgccca ttataatcta gagaagctat ggcatgaggc gaattcagta gatatttcag
    29761 aagctcttgc ttagaagatg aactcagttg tagtcaactg ggtttctttg cttattttag
    29821 aaaaattgat agaaaggtaa agggctagtg gtgtttacca tggagctctt agtatcatga
    29881 ttatggcgac ttatgaaacc tttgcggctg tctatgatgc ggtcatggac gatagtttat
    29941 acgacaaatg gacgaatttt tctctgcgtc atttgcctaa gaccaaggag agaaagaaac
    30001 tcttggaatt ggcttgtggg acaggaattc aatcagtgcg cttctctcag gctggttttg
    30061 atgtgactgg acttgacttg agtgcggata tgttgaagat tgcggagaag agagcaactt
    30121 cagccaagca aaagattgct tttatagaag gtaatatgct aaatttgtcc aaggcaggga
    30181 aatacgattt tgtcacgtgt tattcggact ctatctgcta tatgcaggat gaggtggaag
    30241 taggggacgt ctttaaggac gtgtacaatg cgctgaatga agagggagtt ttcatctttg
    30301 acgtgcactc gacctaccag acagatgaag tattccctgg ctattcctac catgaaaatg
    30361 cggaagattt ttccatgctt tgggatacat atgaggacga agttcctcac tccatcgtgc
    30421 atgagctgac tttctttatc aaggaggctg acggttcctt tagtcgccac gatgaagtac
    30481 atgaggagag gacctatgag atcttgacct atgatatctt gctggaacag gctggattca
    30541 agtccttcaa actctatgca gactttgagg ataaggagcc aacagaaact agcacccgtt
    30601 ggttttttgt ggcgcagaag taggagatta gcatgaccat cacaggtatt atcgcggagt
    30661 tcaatccttt tcataatggc cataaatacc tgctggatca ggcagaggga ctgaaaattg
    30721 ttgccatgtc agggaatttc atgcagcgtg gagagcctgc tattgtggat aagtggacaa
    30781 gggcccagat ggcgctggaa aatggcgcag acttggtagt ggaattgccc tttttagtca
    30841 gtgttcaggc agctgatttc tttggtcaag gagctgtgga tatcttggat cgcttgggca
    30901 ttgatagtct agtttttggg acagaggaag ttcgagatta tcagaaaatc gcttacttat
    30961 acacagagaa aggtgctgag atggagaaat ttgtggaaaa tctgcctgat tccctttcct
    31021 atccccagaa aacccaagct atgtggaagg aatttgctgg tcttgatttt tcaggtaata
    31081 cccccaatca tgttcttgct ctggcctatg caaaggcggt tgcaggacga aatatcaagc
    31141 tgcatccgat tcagcgtcag ggggcaggtt accattctgt gaataaagat gtggactttg
    31201 cctcggcgac agccctccgt caacatcaga aggaccaaga tttcttagaa cgttttatgc
    31261 cttctgttgc cctatttgag caggccagta aggtgatctg ggaagactat tttcccttgc
    31321 tccgctatca aatcttgtca aatcccgacc taaccaccat ctatcaggtc aatcaagaaa
    31381 tggctgtgcg cattaaagaa gctattaaaa cagcccagtc tgtggaagaa ttggtcgagt
    31441 tagtgaccac caaacgttac accaaggcgc gtgtcagacg cctcttgacc tatatcttgg
    31501 tgcaggctag agaaagtgac ttgccagaag ggattcatgt ccttggcttt accgaaaaag
    31561 gcaggcaaca tcttaaatat ctgaaagggc aggtcagtct agtcagcaga attggcaagg
    31621 aaccttggga tgtcatgact caaaaggcag accagattta ccaattggga aatccaagta
    31681 tagcagaaca gaattttggc agagtgccga ttagaataga aacaaactaa gtctactgaa
    31741 aggtaggctt ttttattgta gaaattttag ctaacaaatt gaagataaag tttttggaaa
    31801 atgataaact ccctaataca gaagacaaaa agtcaataaa gaaaattagt atatgaacct
    31861 taatctttat ctttgaatcc gctttatgct tgttatt
//
LOCUS       DAVKMO010000019        31759 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVKMO010000019 DAVKMO010000000
VERSION     DAVKMO010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31759
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.019"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(276..434)
                     /locus_tag="VW361_001024"
     CDS             complement(276..434)
                     /locus_tag="VW361_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU9744083.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEEILVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            complement(505..951)
                     /locus_tag="VW361_001025"
                     /pseudo
     CDS             complement(505..951)
                     /locus_tag="VW361_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014295150.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1027..1239)
                     /locus_tag="VW361_001026"
     CDS             complement(1027..1239)
                     /locus_tag="VW361_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9744084.1"
                     /translation="MTQLLLHADETSYRVLESDSQLTYYWTFLSGKAENQAITLYHHD
                     QRRSGLVVQEFLGDYSGYVHCNMLRQ"
     gene            complement(1248..1553)
                     /locus_tag="VW361_001027"
     CDS             complement(1248..1553)
                     /locus_tag="VW361_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000484476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HEU9744085.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(1540..1734)
                     /locus_tag="VW361_001028"
     CDS             complement(1540..1734)
                     /locus_tag="VW361_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9744086.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEEDGDVPS"
     gene            complement(1931..2254)
                     /gene="tnpB"
                     /locus_tag="VW361_001029"
     CDS             complement(1931..2254)
                     /gene="tnpB"
                     /locus_tag="VW361_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU9744087.1"
                     /translation="MTIHLSILGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGRLTWLSTEKDIKALTSEQVDWLMKGFS
                     ITPKI"
     gene            complement(2238..2420)
                     /locus_tag="VW361_001030"
                     /pseudo
     CDS             complement(2238..2420)
                     /locus_tag="VW361_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2724..4286)
                     /gene="guaA"
                     /locus_tag="VW361_001031"
     CDS             complement(2724..4286)
                     /gene="guaA"
                     /locus_tag="VW361_001031"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU9744088.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            4428..5126
                     /locus_tag="VW361_001032"
     CDS             4428..5126
                     /locus_tag="VW361_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9744089.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKYGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(5169..6067)
                     /locus_tag="VW361_001033"
                     /pseudo
     CDS             complement(5169..6067)
                     /locus_tag="VW361_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
     gene            complement(6076..7011)
                     /locus_tag="VW361_001034"
     CDS             complement(6076..7011)
                     /locus_tag="VW361_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU9744090.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(7008..7733)
                     /locus_tag="VW361_001035"
     CDS             complement(7008..7733)
                     /locus_tag="VW361_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU9744091.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESIEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7817..8452)
                     /locus_tag="VW361_001036"
     CDS             complement(7817..8452)
                     /locus_tag="VW361_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU9744092.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(8454..9281)
                     /locus_tag="VW361_001037"
     CDS             complement(8454..9281)
                     /locus_tag="VW361_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9744093.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINTLFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(9303..10368)
                     /locus_tag="VW361_001038"
                     /pseudo
     CDS             complement(9303..10368)
                     /locus_tag="VW361_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813133.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            10881..11492
                     /locus_tag="VW361_001039"
     CDS             10881..11492
                     /locus_tag="VW361_001039"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9744094.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRTVAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            11537..12265
                     /gene="rlmB"
                     /locus_tag="VW361_001040"
     CDS             11537..12265
                     /gene="rlmB"
                     /locus_tag="VW361_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU9744095.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(12303..13214)
                     /gene="trxB"
                     /locus_tag="VW361_001041"
     CDS             complement(12303..13214)
                     /gene="trxB"
                     /locus_tag="VW361_001041"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU9744096.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(13280..13504)
                     /locus_tag="VW361_001042"
     CDS             complement(13280..13504)
                     /locus_tag="VW361_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU9744097.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(13582..14325)
                     /locus_tag="VW361_001043"
     CDS             complement(13582..14325)
                     /locus_tag="VW361_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9744098.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMPFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFTSYKRTYI"
     gene            complement(14325..15125)
                     /locus_tag="VW361_001044"
     CDS             complement(14325..15125)
                     /locus_tag="VW361_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9744099.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(15283..15639)
                     /locus_tag="VW361_001045"
     CDS             complement(15283..15639)
                     /locus_tag="VW361_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU9744100.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(15633..16163)
                     /locus_tag="VW361_001046"
     CDS             complement(15633..16163)
                     /locus_tag="VW361_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU9744101.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGESQDLSNLLLAPIGTNFEKRVWSYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(16163..16657)
                     /locus_tag="VW361_001047"
     CDS             complement(16163..16657)
                     /locus_tag="VW361_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744102.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            16792..17238
                     /locus_tag="VW361_001048"
     CDS             16792..17238
                     /locus_tag="VW361_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU9744103.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            17235..17882
                     /locus_tag="VW361_001049"
     CDS             17235..17882
                     /locus_tag="VW361_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU9744104.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWILMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASVLQYIAIVYYM"
     gene            complement(17903..18484)
                     /gene="pdxT"
                     /locus_tag="VW361_001050"
     CDS             complement(17903..18484)
                     /gene="pdxT"
                     /locus_tag="VW361_001050"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU9744105.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESYLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(18485..19360)
                     /gene="pdxS"
                     /locus_tag="VW361_001051"
     CDS             complement(18485..19360)
                     /gene="pdxS"
                     /locus_tag="VW361_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU9744106.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(19512..20891)
                     /locus_tag="VW361_001052"
     CDS             complement(19512..20891)
                     /locus_tag="VW361_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU9744107.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            21185..22108
                     /locus_tag="VW361_001053"
     CDS             21185..22108
                     /locus_tag="VW361_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU9744108.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVNGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            22168..22773
                     /locus_tag="VW361_001054"
     CDS             22168..22773
                     /locus_tag="VW361_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9744109.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            22792..23768
                     /locus_tag="VW361_001055"
                     /pseudo
     CDS             22792..23768
                     /locus_tag="VW361_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
     gene            complement(23991..24248)
                     /locus_tag="VW361_001056"
     CDS             complement(23991..24248)
                     /locus_tag="VW361_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU9744110.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(24290..26326)
                     /locus_tag="VW361_001057"
     CDS             complement(24290..26326)
                     /locus_tag="VW361_001057"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU9744111.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGGRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKKIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(26586..27503)
                     /gene="glyQ"
                     /locus_tag="VW361_001058"
     CDS             complement(26586..27503)
                     /gene="glyQ"
                     /locus_tag="VW361_001058"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU9744112.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISNQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            complement(27698..28459)
                     /locus_tag="VW361_001059"
     CDS             complement(27698..28459)
                     /locus_tag="VW361_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9744113.1"
                     /translation="MENLYLVKDDSQLAAFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSNFNAATQIIRESAVPAYTNNRRMVMTPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICTQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWLSFLIVDKLVENLG
                     SVQAVFDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28732..29574)
                     /locus_tag="VW361_001060"
     CDS             complement(28732..29574)
                     /locus_tag="VW361_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU9744114.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     VAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29688..31079)
                     /locus_tag="VW361_001061"
     CDS             complement(29688..31079)
                     /locus_tag="VW361_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU9744115.1"
                     /translation="MDKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKKHFRKGQAEVIAYYPIQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(31314..31694)
                     /locus_tag="VW361_001062"
     CDS             complement(31314..31694)
                     /locus_tag="VW361_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU9744116.1"
                     /translation="MTCQFIRDMLDLPAKNVTILEGSDIHVLPSMPYSAQDFYTSIDD
                     VLAELDNGTQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKHIAP
                     VYAIAIVDSNYFSDDLAFHSFIVK"
BASE COUNT         9372 a         7077 c         5709 g         9601 t
ORIGIN      
        1 cttaccataa ttaaagagat gagagataaa tatcggcagt cttcggactg cctttatttt
       61 tttacttaat ttaatgcagt aaatcatacg attgaaagga atctgcgtta tatgctataa
      121 ttaggtagtt aatctataca tttagaaagg taaaatatag aattggagaa tgatatggga
      181 ttttcatata ataaattgta accgcccaat aacgaagtat attgaaaaat ctccagacta
      241 gagaactcac ggatagttcc taatctggag atttcttatt tgcacttttc ttgtacaact
      301 ttagtccatg gtaaataggc ctctaaaacc tctttgttta cgagaatttc ctcgtttgga
      361 agacattcta gaagatagga tagatatttc tcactattta gttgatgacg tttagctgtt
      421 tccaataagc tcataataat agctcttgct ttagctcctt caaaactttg agaaaataac
      481 caccctcgct tttttaaact gagctcaggc taaaagagtc cactggactc ttttattccg
      541 tcccataacc aatgacttaa tggcgcgttc agctagatta ttggaaagga ccagatgtcc
      601 gtctttcaaa atagtcttaa aggtttcttc atacttgagg ctgtattcaa ttgcccttcc
      661 tagttttgaa cccgataaaa ctgactgacg ccggcaccaa gcaaagaaat cttccattag
      721 gggttggagc tcttcttgac gtttctgtag tcgttcatca gctgacaatg tctcccagtc
      781 tctttccaag gcaaataact gatcacaata ggctaatcct ttagctccta aggatgattt
      841 atccgcttgc ttgggggtcg cttcaaaaaa cttccttctc acatgtaccc aacatccaac
      901 aagttcagct tcttccagtt gacgataagc ttctagcggt tcgcagttta ccaagcttag
      961 cgtcgccttg ctcctaagcc ttggactgct atcgcatagg cagaactaga ggactaaagt
     1021 tctaagttac tgccgcaaca tattacaatg cacatagcca gaataatctc ctaggaattc
     1081 ttgtactact aaaccactcc gacgctgatc atggtggtac agcgtgattg cttgattctc
     1141 agctttccca gacaaaaaag tccaatagta agtcaactga ctatcactct ctagaaccct
     1201 ataagaagtt tcatccgcat gaagtaagag ctgagtcaat agtctcgtta taaaggggct
     1261 ttaggaatag gagctttcac gattttatca ctcggatttt tatcactgca tgcttggcat
     1321 ttgtaagcgt gttggatatg atctatgcgt tttaattgcg caggaataaa gactaattct
     1381 tgtcgttgaa gggttgctcc aatctctttt agatctccct gacaatcaga gcaaatgctc
     1441 tcttctactt gatgatgaac ttcttctgaa tcaaattggg caagaagagc ttggcgtttc
     1501 cctttagatt tcttacgttt gtaggtaatt tcctctgttt caactgggaa catctccatc
     1561 ttcctcagat ggagactctt cctcaaaaag gttgagttgt ccagaggggc aaacactttt
     1621 ctcagaggat tttccataga gcttttgagt cagataagcc acttgttcac gcagaagggc
     1681 aagttcattg gtgagactat caattgtagc actctgttgt tgaatgattt tcaatcttct
     1741 tccatgagct tccctctctg ttttctaact ttattatact aaaaagaaag tcctcatttc
     1801 aatagaaatc acgactttct gatggattta tagtaaaatg aaataagaac aggacaaatc
     1861 gatcaggaca gtaaaatcga tttctaacaa tgttttagaa gcagaggtgt actattctag
     1921 tttcaatcta ctatattttt ggagtgatag aaaagccctt cataagccag tctacttgtt
     1981 cagatgtgag agctttgata tccttttctg tacttagcca agtcagtctg ccgttctcaa
     2041 agcgtttata tagtagccaa aatccttgac catcccagta aaggacttta aagcggtctt
     2101 tacgtccacc acaaaagaga aagacttgac cggagaaagg atccaattca aagtgggttt
     2161 taaccagata agccagtgaa tcgattcctt gtctcatatc cgttttccca cacacgagat
     2221 agacctgccc taggatagat agatgaattg tcatagagca acaccttatc caaaagctgt
     2281 tctaccattt cgagattgag agattgaaaa aaacttactt caagcttgcc aatacgaatt
     2341 ttaagcagaa tatcatttct ctttttagaa tcaaaacgac gagattgtgg aatctctaca
     2401 ggaacaatag gttgtggcat taaaatatcc tccaatagtt ttactttact aatagtatac
     2461 aggaggagct ccatgaatga tagatacctt gttatgacgc gcttactata ttagaaagtt
     2521 ggctctctaa ttaaattaat tctcattata tatatcaaaa gaccgcagct tgaaaactac
     2581 ggtctaattt tttgtccaaa tgtaaaccac ttggaactat tattcaattt attcttttta
     2641 gtaaatgttc ccgttttaat cccagttaca gtttttaatc ctctgtaacc gttgatttta
     2701 caaagctttt aatttttttg cgattattcc cactcaactg ttgcaggtgg tttacttgta
     2761 atatcgtaga cgatacggtt aacatgatcc acttcattta cgatacgtac tgagattttt
     2821 tgaagtactt cccatggaat tttggcaaaa tcagcagtca taccatcgat agaagtgata
     2881 gcacggattg caatcgtgta gtcatacgta cgaccgtcac ccataacgcc gactgaacga
     2941 acgcctgtgt taacagtgaa gtattgccaa atatcgcggt caagtccagc tttagcgatt
     3001 tcttcacgaa gaatagcgtc tgattcacga acggtttcaa gtttctcttc agtgatttca
     3061 cccatgacac ggatagcaag tcctggtcct gggaatggtt ggcgccatac gatatggtct
     3121 ggcataccaa gctctgtacc aagagcacga acttcatcct tgtaaagagt attgagtggt
     3181 tcaatcaatt caaactgcat atcttctgga agaccaccca cgttgtggtg tgacttgata
     3241 gtttgagctg tatccgtacc agactcgata acatctgtat ataaagtacc ttgagcaagg
     3301 aatttcacat ctttgagctt gcttgcttcg tcatcgaata catagacaaa ctcgttaccg
     3361 atgattttac gtttttgttc agggtcagaa acgccagcaa gtttgtcaag gaaacgttta
     3421 gcagcgtctg ctttgacgat attcaaacca aacttaccac cgagcatgtc cataacttga
     3481 tcagcttcgc ctttacgaag aagaccgtgg tctacgaaga tacagatcaa ttgatcgcca
     3541 atcgcttttt ggagaagaac cccaacgaca gatgagtcaa caccacctga tagaccaaga
     3601 aggacacgtt tatcaccgac ggtttcacga atttttttga tctgcatgtc aatgaaatta
     3661 tccattgacc agtcaccttt agccttacaa atgttaaggg caaagttacg aaggatatca
     3721 tttccgtata cagaatgacg aacttctggg tggaattgga taccgtaaat gtgtttatct
     3781 gggttttcga tggctgcgta tgggcagtca gctgatgtac ctgtacgaac aaagtcagca
     3841 ggaatctcag taaccgcatc accatggctc atcaaaacag tctgttcatc aggtgttgat
     3901 tcaaaaagcg ctgatggtgt gtgagttagg gttgattgac cgtattcacg atttccagca
     3961 tcacctgcag gaacaacttt tcctccaagt ttatgggtca ataactgcat accataacag
     4021 attcccaaaa ttggaattcc tagttcgaag atttctgggt caatgtcaaa tgaaccatct
     4081 tcatatacag aatttggacc acctgataga ataattccta caggattgac ttcacgaact
     4141 tcagcagctg aaattttatg gctttttagt tctgaaaaaa caccaatctc acggatacgg
     4201 cgtgaaatca gctggttgta ctggctacca tagtccaata cgatgatttt ttctacatct
     4261 tgcaaatcag ttgaaatgtt gctcatcttt ttcctttctc aaaagaaata tcttttctca
     4321 atattctatc acaaataagg gcgaattacc aactaaacaa ggcgaagttt gactttttct
     4381 agtttattgg ggtacaatag agaaaagata gaaatgaagt gaaaaatatg ctacctgctt
     4441 atatgaaaat ccatgatcag ataaaaaagg atattgacga gcaccgttgg gctattggtg
     4501 agaggcttcc cagtgaaaga gatttagctg agcagtttgc ggtcagtcgc atgaccctcc
     4561 gccaagccgt atctctatta gtcgaagaag gcgtcttaga gcgccgtgta ggaagcggca
     4621 cctttgtttc cagtactcga gtacaagaaa agatgcgagg gacaaccagt tttactgaaa
     4681 ttgtcaaatc ccaaggtaaa gttccctcta gccagctcat ttcctacaaa aaaaccattc
     4741 ccaatgagca agaagttgcc aagctaggaa tttttccaac ggacaatatt atccgaatgg
     4801 agcgggtccg ctatgccgac caagttcccc tagtttatga agttgcttct attcctgaaa
     4861 aattcattaa ggactttaaa aaagaagaaa tcaccagtca tttcttccaa accttgcaaa
     4921 aatatggcta tcgtatcggc aaatctcaac agaccatcta tgctcgcctt gctaaagaaa
     4981 agattgccca ctatttggaa gttgaaaaag gacatgctat tcttggattg acccaggttt
     5041 cctacctaga agatggtact gcttttgaat acgtaaaaag tcaatatgta ggcgaacgct
     5101 ttgaatttta tcttgaaaat aattagatta ccacgcaaaa actctctgtc acagacaaag
     5161 agtctttttt atttttctaa gaataaatct ttcaaagaaa tcaaagttac agcaaacaat
     5221 atcattgcca taccaataaa atcaatggga taaaattgtt cattcattat taagaaggca
     5281 aagaaaaccg ccgatattgg ctcaattgaa gccaacaagc ttgacttgac cggtcctatc
     5341 agactggctc ctttaaggaa agctgtatag gcaaagacag tcccgataag gataatgcct
     5401 gcaaacgcaa ggagaaaatc aagactagtc gggatatcgg cctgtagaat ccctgtaaaa
     5461 ggaagggcga ccaaacctgc tatgaccatt cccacaccaa tgaccaagct gctcccccac
     5521 tttttaatca aggctatggg taaaatgata tacaaagcat aagtcaaggc agaaaagaga
     5581 ccccagaaca gaccagcagg tgtcatggat aactggtcca actgcccatg tgttgcgatc
     5641 aggaaggttc ctccgatggc gaatatgatg gaaactatct ctcccagtgt cggtgccacc
     5701 ctatccttga tacagcgcta taaattaaaa ttccgacagg acaaacatac tgaagcaccg
     5761 tcgctgttcc cgcattggtc tcctgaatag cagacagata ggcgaattgg ttgagaaaaa
     5821 gaccaatcag agcaaaaata agaagagaca gcaaactctt tctatccttt aaaaagacca
     5881 gtattttatc ctttgcagta gcataagcca agagcatgag aattccacca gcgattaaaa
     5941 gacgcaagtt ggtcaagacc agagccgaaa ttccgtgtgc cattaggtat tggccactcg
     6001 ttcctgacaa cccccaagca ataccagcca caactgttag taaagtccct tttaaactat
     6061 ttgacatgtc tctccttact cttctttgcg aatcaagttc atcacttgat tgcggtctaa
     6121 tatccattga gctctctcgt ccttttcata ggtacgattc gataggaaaa tagtggcttc
     6181 ttgcttctga cgattccaca tgataaaggt acctgtatag cccgtatggt ctagccaatc
     6241 tccttccaaa ttccatgcta aagaacgttc cttgtcatcc aaaggagaaa aattttgatt
     6301 taagtctctt gcaaaatcat ctgctaaata gtgttctaaa aagatttgta aatcctttat
     6361 agtcgaaaat aaaccagcac tcccagcatg tctacccagg agacgagcct tgggatcatg
     6421 cactatgcct gcctctacac ctctaactgt tggaacagca agctcaactg gcccaaactt
     6481 ggtttccgtc attccccaag gtttccagac ttgatccttt aaaatcacat ccaaatcttg
     6541 attaaaaatt ctttccaaaa taaagcccaa cagcaaaaaa tggacatccg aataaagaaa
     6601 ggctggctga cttcgtctgt tgagatgaaa catcgcttcc tttaattcag gggctgttaa
     6661 aagatcacga ttaggaataa aaggatcaag gtctgttgca tgagtcaaga gctggcgaat
     6721 agtgatgtct ggataatcac tctcaggtaa aaaatctatt accagtctat caatatctaa
     6781 ttgacctatt tcccacaaga aggtacaaac tgtgccaacc ccaacaacct tgctgacact
     6841 agctaggtca taaactagtc ctgcctcagt ctgcaagcca tgctctgggt cactctggcc
     6901 taaatagaac tctgtccatt gattgtcctt aaaatacgca aaagaggctc cgggataaat
     6961 ccctgcctcg atttgttctt ctattttttt aataatcttg gtccacttca tacttcttca
     7021 aaccacaatt caacattatt tctatcttta ccaaggaaga atttttcaga cttaggaata
     7081 aaatattcaa tagactcaaa cttctggcga agacttgcta tgtctaattc attgaccaag
     7141 aacttgagca tagataagtc ccaggtaacc gtattgtcca cagtcaaatc ctgcccctga
     7201 gctggaataa aatcaaggga tgccccaatt tcagatgatt ccaagaaact ttcgatatca
     7261 gttgggagat gtaattccat agaaatctca aatttactta aagaaattga tgccaaatct
     7321 gtttgaaatt caggcttttc tcctacttct actagacttg ctctgtcatc ttccgcatga
     7381 atcaaaatca aatcatcttc tggtgagaaa atttcaaaag cgtagccatt ttgaccttta
     7441 tataatcgat gaatcgaatc tgttttagat aagattcctt caatttctaa gggattttcc
     7501 accttgacaa tcaatctagc tagttttttt cttccctcta ccttacgagt acgcatactg
     7561 ggagcttctt ctaaaaccag cttttcaaga cccgtttggt cacctagtga cagaaaggcc
     7621 gattcttcta acaaggcctt cattccaagg gtttcaatat aaaatgtttc atttaatttt
     7681 ctattattag cttttaaagt aggaataatc cgtacaatct gatttacatt cataaattcc
     7741 tccgtcactt tttattttaa aggattttag aattttttac aagatattat gctcaaattt
     7801 aacattattt agctatttag taaagatagt ctttcaaggc ttttgacaaa gcctgataac
     7861 cagcaatact gaggtgcagt ccatcagttg tatattcttt tttgagttgg cctgcttggt
     7921 ctgtcaaaca atcaaatact ggcacaaatt ccacctgcat ataggcagat gcaagctctt
     7981 gataggcttg attccagttc tgaatttttt cattcgagcg gatatagact gcctgctggt
     8041 actcctctcc ctcattgaca ggcaaaatgg aaagcaattt aatctctgtc aatggataat
     8101 cgcgagcaac ggattgaatg atagcttcga gattattgag agcctcattc acaggaacat
     8161 cctttccgat atcatttgtc ccaatcagaa gaaaaatttt atctactgct ccaccatata
     8221 gatgagcatc aaggttctct agtaacagtc ctgtctgata gccacgaatt cctcgattga
     8281 caatcgtctt tgaagtccca aatagctcct gtagaggata atactcgaca atggaatccc
     8341 caataaaaag aatgtttggt tctacaacag aaatgtgatt taggtgacga tacttggttt
     8401 gaattttttc ttgttccttt aggagccaat tttctaataa ctgtactgcc acttcattct
     8461 cctttttcta accagttttc caagacttga taaactcctc cttggctgtt ggctggtgct
     8521 agagcagtcg ccacagcttt ggctttctca tcagcatttt ccatcgcata ggcaattcca
     8581 gccatttcaa gcatttcaac atcattttca ctatcaccaa aagccatgat ttcttgggat
     8641 ttcaagtccc agcgcttgag taattcctcc aagccccatg ctttatgaat cccagcttgg
     8701 aggatatcaa tgcaaccata gccactggat acagctcgga cacggccatc aaagagagta
     8761 ttgatttctt ccaaaaccga actcaaacgt tcctcaccaa caaccatgct catcttgagc
     8821 acaccaccaa agaggtcaga tgttaattca tccacaaatt gcatccgttg gtagaatttt
     8881 tcaatcattt ctggagtcat aaaactttca agatctgtaa aaatcgtacc ttccttgaca
     8941 aaatcaccct tcatccccgt tacaacaaac tggtcctgac acgctcgacc cttgaaatga
     9001 gccaaagcct tgttgacaat ggcgtcatcc catgtctgag cctgaatcaa ttcattgttt
     9061 tcaaaaatac gagcgccatt agcaacaacc agaaccactc gatccaccaa gggactcagt
     9121 agttgtctca tgcggtgaat ttcattgccc gtcgcaatga caaaacgaat gcccctttga
     9181 tccaactgat ctaaaatctt ttccaatcgt gggagatcaa gctgacctct agcatccagc
     9241 aaggtcccat ccatatctgt cgcaattacc ttaatcatca tttactttcc tctggattca
     9301 aactaatacc acttcaatcc cacatgttca ttcatttctt tataggctgt atcaattcgt
     9361 tccttagtcg cttcatctaa ctggtcacga tgactgccat cctctataaa atcttccaaa
     9421 atataagttt ggtaatgata caagggatat ccttctggtg aaaaggttcc ctttggtgtt
     9481 cgattgaccc aagtaggatg atctttagct gttccgatag ttgtttttcc atcattcttc
     9541 ttgatggtga catccatgag aacaccacgt tcagtccact tagcattctc ttcatctccc
     9601 atagattcaa ttcgttgatt ggaaatgaag ttccccattg aatagataat gagtttctta
     9661 tctccatctt tttcaaccgt ttcagatggc tcaacaacgt gaggatgccc tccaaagata
     9721 atatccgctc cccaatcgat catcttgtga taaagagctt tttgttcttc agttggttcc
     9781 aatcgatact caacacccat ctgaggcatg ataatggtga tatctgcttc cttctctgcc
     9841 cgttcaactt cagccttcat cttatcttcg tttaaatcta aaagataacg attatagtct
     9901 tcctgagaaa tatactgctc aattccattg aaaccatagg aataggctga caatgcaacc
     9961 ttgataccat tcacttcctt aatgaccagc ggaacctgat cacgtggttc gtgcgtataa
    10021 actccgattg gagtgattcc agctttctca ataatatcgg ccgttgaaat aactccctca
    10081 atttgcgaat ccaaaatatg attatgagct aaatccagca catgataacc tgcctcctta
    10141 atagcatcca taacttcagc aggagcatta aagagaggat aacccgctaa ataatgatcc
    10201 ttattaatgg tttcttcaaa atcaccaata gctaaatctg cttgcttagt ccacttgctt
    10261 gagccaagga gtcacatact caaaattttc atgaaagtca taggtaccgt cttctttttt
    10321 agctgaaaag aaaagtccat cgtggtagag caaatccccg tgggccataa ttctggcagt
    10381 tttttcctct tcctactcct gagacttttg cttagtcccc tcttgagaaa tagtatctcg
    10441 tttttgacta gtcaagggat tccttggaag ctttcaaaca acaagaccaa gcccattgat
    10501 aaaccaactg ctagcaagag tatcgccaca aatcccttat tgctccactt gcgataactc
    10561 ctaaaaagtt taccaagccc ttcataaaac gaaaagctaa accaccctga tttcgatttt
    10621 gtcttctttg tatcttcgtt ctccctactt tcttatgcaa gccttttctt tttattatat
    10681 cacagataag tatttctttc acaattgaat tgaacttccc atctattttc tataaatcct
    10741 aaatgccata atgctttcaa ttcttgtcat tttgtgatat catgtagagg aaatgaacta
    10801 atccacagtg gcttattcca agtataccac ttgggctttg gcagtagcta actgcactaa
    10861 acataatata aggagagaaa atgtctgcaa tagaacgtat tacaaaagct gctcacttaa
    10921 ttgatatgaa cgatattatc cgtgaaggga atcctactct acgcacggtt gctgaggaag
    10981 tcactttccc cctatctgac caggaaatca tcctaggcga aaagatgatg caattcctta
    11041 aacattccca agatcctgtc atggctgaaa aaatgggact ccgcggtggt gttggactgg
    11101 ctgctcccca gttagatatc tcaaaacgca ttatcgctgt tttggtacct aatattgttg
    11161 aagaaggcga aactccacag gaagcctacg atttggaagc cattatgtac aatccaaaaa
    11221 tcgtctctca ctctgttcaa gatgctgctc ttggcgaagg agaaggttgc ctgtctgttg
    11281 accgtaacgt gcctggctat gttgttcgcc atgcccgcgt tactgttgac tactttgaca
    11341 aagatggaga aaaacaccgt atcaaactca aaggctacaa ctccattgtt gttcagcatg
    11401 aaattgacca cattaacggt atcatgtttt acgatcgcat caatgaaaaa gacccatttg
    11461 cagttaaaga tggtttactg attcttgaat aaagaaaatc ccgttgcaag acggggtttt
    11521 gtgttataat agaggcatga aaacaaatga tattgtctat ggtgtccacg ccgttaccga
    11581 agccctcctt gcaaatacag gaaacaaact ctacctccaa gaagatctcc gaggtaagaa
    11641 tgttgagaaa gtcaaggaac tagctacaga aaagaaggtg tccatttctt ggacatcaaa
    11701 aaaatctctc tctgagatta ctgaaggtgc tgttcatcaa ggttttgttc tacgagtgtc
    11761 tgaatttgcc tatagcgagc tagattacat ccttgcaaaa acacgccaag aagaaaatcc
    11821 acttctattg attctagatg gtctaaccga tccccataat ctgggttcta tcttgcgaac
    11881 agccgatgcg accaatgttt caggtgtcat cattcccaag caccgtgctg tcggagtaac
    11941 tcctgtcgtt gccaaaacag ccacaggtgc tattgaacac gttccaattg cccgagtgac
    12001 caacctcagt caaaccttag ataaactcaa ggatgaaggt ttctggacct ttggaacgga
    12061 tatgaacggt actccttgcc acaagtggaa tacaaaaggg aaaatcgccc tcatcattgg
    12121 aaatgaagga aaaggtatct ctagcaacat caaaaaacaa gtcgatgaga tgattaccat
    12181 tccgatgaat ggacatgttc aaagccttaa tgccagtgtt gctgcggcca ttctcatgta
    12241 cgaagttttc cgaaatagac tataaaaagt ttccagtcat ctgattggaa acttttttat
    12301 aattaactat gttctgtaat gaatttatag gcttcttgac cagcgatagc tccatctcca
    12361 accgctgttg ttacttggcg aaggtctttc aagcgaacat ctccaactgc aaagataccg
    12421 tcgactgcag ttttcatgtg gttatctgtc acaatccatc ctgcctgatc ttggatattc
    12481 aattctttaa caaaatcgct aagagggtcc aatccaacat agataaagac accaccgaag
    12541 acttgttctg tcacttgacc tgttttcaca ttttcaaata cgactgattc tactcggttt
    12601 tcacccttga tttcccttac tacagaatcc cagataaagc tgattttttc attcgcaaag
    12661 gcgcgatctt gtaaaacctt ttgggcacga agttggtcac gacggtgaac aatggtaaca
    12721 gtcttagcaa aacgagtcaa gaagagggct tcttcaacag ctgaatctcc accaccaact
    12781 accaataaat cttggtcacg gaagaaagca ccatcacaca cagcacagta agaaacacca
    12841 cgactgttca gttcttcttc tccaggtact cccaaaggac ggtgtttaga accagttgct
    12901 acgataactg tacgtgtttc atatgtttgg tcatcagtca tcactttctt aaaatcacca
    12961 tggtcttcga cattttcaac ataaccataa atgtgctcaa caccaagatt ttcaagtggt
    13021 tcaaacatct tttcagccaa ttcaggtcca ctaatattag cgtatcctgg gtaattttcg
    13081 atatcagatg tattattcat ctgaccacct ggcagaccac cttcaatcaa agctactttt
    13141 agattgcttc gagcagcata caaggccgca gtcatccctg caggtccagc accgataata
    13201 atagtatcgt acatatagat tccttctttc ttgttgtaac tatctttatt ctaactcttt
    13261 cttgtcaatc acgcaaggat tatgccttga aaacaagaat taaactcata accgcaaagg
    13321 ataatactgg gacaaccaag actccaatca taatcatatc atagagatgg gcttggcgag
    13381 ccttggctgt cttatcaact cccgacatgg ctctcagacc aatccaaatc cctaaaaaaa
    13441 tcagaacaag gatggtggtc aagatcaaac tctcgaaata taaagaaaat agttgcagta
    13501 gcatgatttc tctcatttct atctttttta aagagtaaac tcagctagtc caactaactg
    13561 agttttcctt tatctattat atcaaatata agtccgtttg taactagtga agaattcttt
    13621 tgtccgctct tctttagggg tgtggataat ctcatccgga gttccagact cgatgatttt
    13681 ccccttatct aagaagagaa ttttatccgc aacttgggct acaaagggca tgtcatgact
    13741 gaccaaaatc atggtctgac ctgacttagc agcatctgca atagactttt ctacttcacc
    13801 gaccaattct gggtcaaggg ctgaagttgg ttcgtctaag agcaaaacat ctggtttcat
    13861 agcaagcgca cgcgctaggg caacccgttg cttctgtcca cctgataaat ggcgaggata
    13921 atggttttca cggtccgaaa gcccaacctt agccaactct tccttggcaa tcttagtcgc
    13981 ttcttggtca gataatttct tgacaacaac caagccttct ttcacattat caagtgctgt
    14041 tcggcgttca aataaattaa actgttggaa aaccatagac aacttacggc gtagggcaag
    14101 gatttcttct tgagtgattt tagaaaaatc aactgaaaaa ccatcaatct gaatagagcc
    14161 actgtcaggt gtttcaagat aattgagact gcgaagaaag gttgatttgc cagctcctga
    14221 agaaccaatc aaggctacaa cttccccttt ttgaatatcc aagttcagat gatccaagac
    14281 agtctgtcct gaaaaggatt tgcttaaatt cgaaatctta atcattaacg aaggtctcct
    14341 ttcacatctg tttgcactgt atcaggtgca gaaatagcca tttttctctc gatgaaacga
    14401 ccgaggcttt caattccgat attgactacc caataaacaa gggcaacaga gatgaagcgt
    14461 tcaaaatagc gataatcagc tccacctaga atctgagctt gggcaaagac ttccacaaca
    14521 cccgcactaa aagctagaga tgttcccttg gtcaaaccga tgagggaatt aatcaaggtt
    14581 ggagtagcta ccaccgctgc attaggaata atcactcgtc gataaacttg cgctcgggtc
    14641 atacccagac tgcgcgccgc ctcaatctca ccaggattaa ctgagagaat ggctgcacga
    14701 atggtttcac tagcataagc tgcctcatta aaggcaaaag cgacaatcgc aaaagctgca
    14761 gctggaatcg cattgatatt gagaccagtt ccccattgct gattgagggc tttcaaagcc
    14821 aaagggattc cgtagtaggt caacatgagt tgcaccaaaa tcggtgtccc ttttaagaaa
    14881 ctaacaaaga aggcctgcaa gggatataaa atcttgacac gattgatctt cacaatggca
    14941 aaaagaagcg ccaaaaccaa gccaaaaagg gcaccgccaa ttgtcaacat aattgttgtt
    15001 ggaagttgtt ggacaattct agggattcca tcaaagaccg aacgtaggct aaacagcttg
    15061 ccatccggaa tcaattgcat caagttttgg taccaatctg atgctaaaat cgttgtaaca
    15121 ttcataaaaa catcctcttc tgataatgat tcattctacc atgcttctgc cgtcaatgaa
    15181 attatttgct acggtcagat acagactttg tctacctact agtttatcat actttgaaac
    15241 agggaagtta tatattttat ctatcaaaga gatagataaa aactatttca gtcccagttc
    15301 ttcataagat tttcgataac cgatttgctt aacagttcca ttttctacta aaatgggccg
    15361 ttttaacaac ataccgtcac ttgctagcaa ctcagccgct tcttggtttg acaaacttcc
    15421 taccttatct tttagcccta attcacggta tttgatacca ctggtgttga aaaattgctt
    15481 caattcaaat cctgaggttt ctagccaatt caaaatgact tcttggctag gtgtttcttc
    15541 cacgatatgg acggctttat agtccacacc taattgattt aattcttgtt ttgctttttt
    15601 acaagttgaa catttggggt attcgataaa ttctaacatg tgcttctcct tctattgttt
    15661 ctatctttaa aatctactcc ttcatgctcc aagagccaag ctttcttttc cactcctgca
    15721 gcataacctg tcagacgctt gcctgctccc aacacacgat gacaaggtac taggatagac
    15781 caaggattgc gtcccactgc tccaccaatt gcttgagcag aagccacttg caggtcttga
    15841 gcaatttgtc cataggtcac tgtctgacca taaggaattc cctgtaaata ggaccaaact
    15901 ctcttttcaa aattcgttcc aattggcgcc aagagcaagt tggataaatc ctgagactcg
    15961 cctttaaagt aatcatctaa gcaagcaata actgggtcta aaataggatg actaacaact
    16021 tcttctatcg tttcatctcc tagtcccctc tcaaaatgct tctgctcctg aacccaaatt
    16081 ccatacaaat aatggtcatc agctacaagt gatagaatac caattggtga ggagtagagt
    16141 atttttacat acttcttttg cattatttct ttaatttttg ataggccaag cgttcgccat
    16201 ctactggcac cttaccaact tgtttaaaac caagtttttc aaaaatatgt tgcataacct
    16261 tgttttcagc atgcgtatct gagcgaaaat caagataatc aaaaccttca atcaagccct
    16321 ctaagaaggt ttgagcaact ccttttccct gcacatctgc tgccacagca atacggtgaa
    16381 agactagata ctctgactct ccagcttgcc agtttccctc ataaatagct tcataggcct
    16441 cctctggact cttggtcaca gcagcatagg ctagcagttc tccctcttcc aaggctacgt
    16501 aggcttgccc tgagatgata tcatcgataa taacatctgc atttggatag ccattttgcc
    16561 actggtcact accagcatct gctaaacatt ttttggcatc ctccatcacc tgcatgatgg
    16621 catctacttc atttggaaaa gctaaacgaa tttccatctt ttttcctcat ttctgactag
    16681 tttctcccat catagcataa tttaagtatt tctacaagca gttaaaactt gactttgtgt
    16741 ttttgttatt ttataatcta gttatcaaaa ctatataaaa aggagttgaa aatgaaaact
    16801 accttttcct acccaaaatg ggcagaaatt ccaaacattg acctctatct ggaccaggtt
    16861 ttgctctatg tcaatcaggt ctgcgcccct atctctccta ataaagacaa gggcctaaca
    16921 gcatctatgg tcaacaatta tgtgaaaaat ggttacctga caaagcctga caaaaaaaaa
    16981 taccaacgcc aacagattgc ccgtttgatt gctatcacaa ccctcaagtc tgtattttct
    17041 attcaagaaa tagcccagac acttaatact ctacaaactc aagcaagttc agaccaactc
    17101 tacgatgctt ttgtggacta tatgaaccaa ggaattgacc cagctaaccc tattatccaa
    17161 accagctgcc aaaccgttaa actctatcat caaactctag acttaatcga tcatactcaa
    17221 gaggaggtaa tccaatgaac actagtctta aactcagcaa acaactcagt tttggagagg
    17281 agattgctaa tagcgtgacc catgctgtgg gtgcagtcat catgcttatc ttgctgccta
    17341 tttcatccat ctatagttat gaagcacacg gatttttatc ctctatcggc gtttccattt
    17401 tcgtcatcag tctctttctc atgttcctat catccaccat ttatcactct atggcctatg
    17461 gttcgaccca caaatatgtt ttgcgaatca ttgaccattc tatgatttac gttgccattg
    17521 ccggctcata cacgcccgtt gtcttgacct tgatgaataa ctggtttggc tatctgatta
    17581 ttgtcatcca atggggaacg accatctttg gtattctcta taaaatcttt gctaaaaagg
    17641 tcaatgagaa atttagcctt gctctttacc tgattatggg ctggttggtt ctggctatca
    17701 ttcctgccat tatcagtcaa acgacacccg ttttctggat tctcatggta actggcggac
    17761 tctgttatac agttggagct ggattttatg ccaagaaaaa accttatttc cacatgattt
    17821 ggcatctctt tatcctagct gcgtccgtac tccaatacat cgctattgtt tattacatgt
    17881 aaaaaagttg agaaattcaa tctcaacttt tttctttaca catattgata aagtactggt
    17941 gcaagcgcac atcatcagtc aattctggat gaaaagaact taccaacata tttttttctt
    18001 gggctgcaac aatttgattg ttcactgttg ctagaatttc tacaccctca ccaacactac
    18061 tgataatcgg accacggata aaggtcattg gaatcttgcc aactccctta cattctgctt
    18121 ccgtgtagaa acttcctaat tggcgcccat aagcattacg ctcgaccacc atatccatag
    18181 ttcctagata actctctttc tgagaagtga tttccttagc cagcaaaatt aagcccgcac
    18241 aggtcccaaa cactggtaag ccagatagaa tggcttctcg gatgggaagt agcatgttct
    18301 ggtcacgtaa gagcttgccc atggttgtag actcaccacc aggcaaaatc aaacccgaca
    18361 agtcactctg atcttgctga aaatcatcta gatttctgag ttctacactc tcgacaccta
    18421 attgatctag cacttttgca tgttctgcaa aggccccttg caaggccaat attccgattt
    18481 tcatctattt tcctcgttca gccatgagaa tttggatttc attttcatta ataccaacca
    18541 tggcttctcc taaatcttca gagatttgag ctaggatttg aggattacgg aagttagtca
    18601 cagccttaac aatggcactc gctcgtttaa caggatctcc tgacttgaaa atacctgaac
    18661 cgacaaagac cccctctgcc cctaattgca tcattaacgc agcatctgct ggcgttgcaa
    18721 cacctccagc agcgaaattt acaactggca attttccatg ttcatgaaca tattggacca
    18781 attctacagg gacttgcaaa tccttggcag caacataaag ctcgtcctca cgtaagtttt
    18841 gaatgcggcg aatttcctga ttcatcatac gcatatgacg aacagcttgg acgatatccc
    18901 ctgtccctgg ttctcctttg gtacgaatca tggaagcacc ttcagcgata cgacgcaagg
    18961 cttcacccaa atccttagca ccacagacaa aaggaacttg gaattctttc ttgtccacat
    19021 ggaaacggtc atcagctgga gatagaactt cactctcgtc gatataatca atttcaatag
    19081 cctctaaaat ctgagcttca acaaaatgcc cgattctgac cttagccatt actggaatac
    19141 taaccgcttc ttggatttcc ttaatcatct ttgggtcgct catgcgggaa actcctccag
    19201 ctgcacgaat atcagccgga attcgttcca aggccatcac agctgccgca ccagcagctt
    19261 ctgcgatacg agcctgttca ggattctgca catccataat aacaccaccc ttgagcatct
    19321 gtgccaagtt tttatttagt tcataacgat tttcagtcat ttgttttatc ctcatcattt
    19381 gtattggtag ctaccttttc attttaagtc agaacagaat gaagcacaag ataaaaaaac
    19441 tataattgta tggggacaga ttggctaaaa actatctgac cttaacttaa ggccagatag
    19501 ctcattcatt tttatttttc agccgtaagg gcagccattg tgatgtagtt gtatggttta
    19561 ttgaagtgtg gcaagaagaa gaggtctgtc aatgccaatt tatcaattgt cacatgctct
    19621 tggatagcaa gtgagaacat gtggattccc atgctaattg caatatcatg tgaaaccatt
    19681 tgggcaccaa gaatttcacg gctatctttg tcaaagacaa tcttaattgc tacttcatgg
    19741 ttgtcatgtt tcatgaattc tggtttttga agatcgttaa agcctgtttc agttgcgttg
    19801 taaccagcag ctttcgcttt ttcaagagtc aaaccagttg aaaccatgtg aagaccgtag
    19861 attgagatac catttgaacc ttgaacaccg attccttcca attcatgtcc acaagcgttg
    19921 taggcaccaa cgataccagt gcgaacagca tttgaagcaa gagcgatata gcttgtatct
    19981 ttacgagcat tgtcataaac agtcgcacag tcaccaacag cgtaaacgcc tgggatagat
    20041 gtttcttgtt tcttgtctac aaggaaggca ccgttgcgga agagttcgat cttaccatca
    20101 gcaagggctg tgtttggacg gaaaccaact gcaaggataa ccatatccac gtcaaagctt
    20161 tctttgtcag taatcaagcg ttcaacttta ccatcacctt cgattgcttt aacagtttga
    20221 cctagagcca agcggatgtt gtgatcttcc aagttcttcg ccatcatttg tgtgaagtct
    20281 ttgtcatagt aaccgttcaa gacagtatca acgatatcaa caaggacaac ttcttttcca
    20341 agacgttcaa aggcttcagc aagttcaaca ccgatgtaac caccaccaac aacggcgata
    20401 cggtcgaggt gttggctctt gtcagaaagt ttattgataa cttcttcagc attttggtac
    20461 aatttcacga attgtacgtt ttcaagagtt gctttaaatt cgcggtttcc tttaacaatt
    20521 tcaacacctt cgattggtgg caagattggt gtagaacctg tagcgaaaat caatttttcg
    20581 tatgattctt tgtgctcttt tccttcaact tccgctgtaa ctactttgtt atcatagtcg
    20641 attgaaagaa caggtgagtt catgtaaact ttagcacctt tagcttccaa tttttcttta
    20701 tcagaataga acaagccttc agcaccgtca atttgttcac caatccaaag agccattcca
    20761 catcctagga aagagatgtt agagttttgg tcaaatacaa caatttcgtt ctcatttcca
    20821 aaattatcca acatggtatt gatacatgct gtaccagcgt ggttagcacc gactacaacg
    20881 attttactca taaaaatttc ctgccttcat tctaaattta ccttactagt ataccattta
    20941 ccgttagcgt ttacaagggg ggtactatta tttcagcatt ttttatcaaa aataattccc
    21001 catttatcct gttttcaagc ctcatgaatt ttatgagcat atttcttgac tttttccaaa
    21061 ttttgtttgt gaaaattcta actttatggt attctaataa catgaaaata aaatgtaagg
    21121 gcttcaattt agataattat tttatattac aacttatttt ctataagaga aaggagttgg
    21181 tagcttgact cttcgttcac attctgaacg gctaatgggg actactatca ctatttcatt
    21241 agtggatgag caagccgata tctttctcca aaaatccttt gacttgctca aagagcttga
    21301 ataccgcttc aacgccaata gtcaagaatc tgagttgatg gaaatcaatt atcaagcagg
    21361 aatatccccc gtcacggttc atccagacct gtttgagctg atttcacttg ggttagagca
    21421 tagcctagcg ctctctagcc acctcaatat cagcattggt cccttaattc aaacctggcg
    21481 tatcggtttt tcagatgcca aggtcgccca gcctcaagaa attgaatcgg tgctgcctct
    21541 aatcaatcct catggtatcg agttagattc ttctacttct actgtgtttt taaaacagaa
    21601 aggaatgaag atcgatctag gttgtttagc caaaggatac agtgcggata aggttgccca
    21661 atttcttagg aaagaggggg tgacttctgc cttgatcaat ctgggaggga atatcctgac
    21721 cattggaaaa aatcaggcaa gaggggataa cccatggcaa atcgggattc aagacccagc
    21781 caatcctagg ggaaatcatt taatgaccat ccctgttgtc aataaatctg tcgtgacttc
    21841 aggcatttat gaacgtcacc tgaccgtcaa tggacaagat taccatcaca tttttgacag
    21901 tcaaacagga tatcctgttg aaacggaact agcgagtcta acaatcatct ctgataaatc
    21961 agtcgatggc gaaatctgga cgactcgact ctttggagaa agacctgctt ctatcctctg
    22021 gcaagtcgaa agtttggagg gcatcgaagt catcctcatc gataaagaag gccacctaag
    22081 ctgttcttca ggaattccta ctctatagag acaactgttt caatggaatt ttaaaattgt
    22141 attatgtaaa aagagaaagg aaatctcatg ttaaaactta ttgctattgt tggaacaaat
    22201 tcaaaacgtt ctacaaaccg tcaattgctt caatacatgc aaaaacactt tgctgacaaa
    22261 gctgaaattg aacttgttga aatcaaggcc attcctgtct tcaacaaacc agctgacaag
    22321 caagtacctg ctgaaatatt ggaaattgct gctaaaatcg aagaggcaga tggcgttatt
    22381 atcggtactc ctgagtatga tcactctatt ccagctgttt tgatgagcgc tcttgcttgg
    22441 ttgtcttatg gtatttaccc acttttgaac aaaccaatca tgattacagg tgcttcttac
    22501 ggtacgcttg gttcatctcg tgcccaattg caacttcgtc aaatcttgaa tgctcctgaa
    22561 atcaaggcaa atgttcttcc agatgaattc ttgctctcac actctcttca agcatttaac
    22621 ccaagtggcg acttggttga ccttgatgtt atcaagaaat tggatgccat ctttgatgac
    22681 ttccgtatct ttgtaaaaat cacagaaaaa ttacgtaatg cacaagaatt acttcgcaaa
    22741 gatgctgaag actttgactg ggaaaatttg taagatagga gaccaaaaag aatgaaattt
    22801 gttggacttg ttggatcaaa ctacgatcaa tcatataacc gtaagctctt ggaatttatc
    22861 cgccgctact tcaaactcaa atttgaatta gaagttcttg aaattgacga agttccaatg
    22921 tttaaccaag atgaaaaatg ggatgaaagt ttccaattac gttatttata taacaaaatt
    22981 actcgtgcag atggtgttat cattgctact cctgagcaca accacactat ctcagcttca
    23041 ctcaaatctg tacttgaatg gctttcatac gaagttcatc catttgaaaa caagcctgtt
    23101 atgattgtgg aaaaccaatc gctacaacca tcacagaagt tgaccctgac gatccagaat
    23161 gggtagaaaa agttgcagca atcactggtg ctgtttctgg tgatacctat gtcaaattgg
    23221 accacggtat cctaacagtt aaccaaattg atatgttctt gaaagctatg ccatttgaat
    23281 tgacatacgc tgatgacaac aaccaattcc tctactacaa caacgctcac caagatccag
    23341 acactatgtt cgctaaacgt gtaccacctc aatcaggtag ccgtatgtcg actgttcatg
    23401 gttctcttcc accagcacgt atgaagaacg tagagtgggt tatcggaaca cttcgcaacg
    23461 gaaaccaaga atacgtccgt acgatcgttc caggttctcc tgcaggtgtt atcaacactc
    23521 acaactacca agcaatgtac tatcctgatg gatcatacgc tggtatcaat gaaatcgtct
    23581 ttaacttcca accatggctt gactggtacc taaaagagac tggtcaacgt ttggtgggtg
    23641 gtagcggacc atttgctcct gctgccggag gtcatggaga cgccgatgct acttctggcg
    23701 cttctgattc aggggatgct ggaggccacg gtggtgacgc agacgctaca gccggtgcaa
    23761 gttactaatg atagttttta ggaaccatta tggttccttt tttagcgaaa aaagactagc
    23821 aaacacaaac tgctagtctc tttgttatcg tttcatctat ccttgttaaa agaaagaata
    23881 cttatactca atgaaaatca aagagcaaac taggaagcta gccgcaggct gtacttaagt
    23941 acggcaaggt gaagctgacg tggtttgaat ttgattttcg aagagtatta ttatgaattt
    24001 gggtcatcaa gactacggcc atgtaatcct ttttcacgtt gtacttggcg tagtttttct
    24061 ggtgtaacat cgtttccttc ttcgtccaca attttgattc cttcaatgtg gtgacgaaca
    24121 gcgcggcgat aaccttcgat gtactcctca cgtagtttgg cttgttccac tttttcttct
    24181 ggtgttaaac cttctgtttt tttcttttta gcaagctcat tgatacgagc aatttttttc
    24241 ggatccattt cttctccttt gtaataagat aaagtccgtt tatcaaattt tatttagtgt
    24301 taatttggtt aaaacaagca aacttagctg ctttcttggt tagttgtgac aagattgcca
    24361 aacgattttg acggacagcc tgatcttcag ccattaccat agtattttca aagaaagcat
    24421 caatgactgg gctaagcgca aagagttgtt tcaattgctg acttgcaggt cctgataaaa
    24481 cgagtgtttc tactgcttct gccaaagctt tttcttggtc attctcaaat agtgctgaat
    24541 caactgtagc aaccccttct gccttctcag ccaggttaaa ggcacgagaa agtgattcaa
    24601 cagatggttt aaaatcttct tccttgctta cttctacgag agcacttgct gcttccaaca
    24661 tatctgccac aacaaagttt gaacctgcaa gaactgcttc cttgatatct tttggagtag
    24721 agcccatcat cttatcaaca cgagccttga taaagtccat aacctctgct ttattttcat
    24781 aagtcaaact gtcaaatttc aatgcataaa ggctatcaat cagctcatcc atagcaatgt
    24841 gccaaccaaa ggcatccaag atacgaacca caccttgagt tgcacgacga agggcataag
    24901 ggtcattaga acctgatgga atcaatccta ctgagaagaa actcaaaatc gtatccaatt
    24961 tgtctgcaat ggctagaact gcaccgacct tgctctctgg aagttctcct tcagctgatg
    25021 taggcatgta gtgttcacga atagcagctg ccaccgctgg agtttcacca gcaagaaggg
    25081 tgtatttttc acccataatt ccttggagtt cgtcaaattc accaaccata cctgtcaaca
    25141 agtcaaactt gtaaatggct gctgcacgag caaggtcaac tgtttcatcc actgacaaac
    25201 cagctttttc tgccaaaagt acagtgattt gacccgtacg aatcatgtgt tcacgaaggg
    25261 aaccaatctt ctcatggaag gtgacattgt ttaatttttc aacaagatct gaaatcacca
    25321 atttttggtc ttcacgccag aagaattctc cgtcttccaa gcgggctacc aagacttttt
    25381 catttccttt gatgacattt ttcaaacgct ctgcgtttcc gttacgaaca gaaatgaagt
    25441 ttggcaagag ttttccatct tgatcacgaa caacaaagta acgctggtgt tccttcatag
    25501 aagttaccaa gacttcttct ggaacttcaa ggtatttagc atcaaaactt cccatgaagg
    25561 cagttgggta ttcaaccaaa ttcaagactt cattcagcaa atccgcatca atttcgatac
    25621 gtacaccatg ttttgcctca attttcttga tttggtcaac aatcatttgc tcacgttcac
    25681 atggatctgc gattacaaac tgcttacgaa ggtcttcttc atagctcaat gctgactgaa
    25741 ttttggtttc tttccccaag aaacgatggc cacggctcac acgacctccc ttgatatcaa
    25801 ggaaatccaa gtcaaactct tgctcatcca agagaacagt taaagtgtga acagggcgga
    25861 tgtattcaaa gctgtttcca gcccagtgca tgctgacagg gaaagtcaat gacttcaaga
    25921 catctacaac accaggaaca atggcttcaa ctgcttgacc aacttcttcc ttagtgacat
    25981 agacatattc ttcacccttg atttcacgga attcgatatc ttcaacagtc aagccttttc
    26041 cacggacaaa tccttgagct gctttggtga agtttccatc actatccaag gcaattttct
    26101 ttgctggtcc cttgaaatct tctgtcaaat cagactgttt gtctgataaa ccagtcacac
    26161 gaacagccaa acgacgtggt gttgagaagg tttgaatggc ttcaaaagac aggcggtttt
    26221 ccttgaggaa ggctgccatt ttttcgccta gttgtttttc acttggtgtg acaacatagg
    26281 ctggtaattc ttcaagaccg agttctacta ataagttttt tgtcatgttt tttcctttac
    26341 attttcttca atcttttttg atatgcacct taggtactgg ggacgtcgct aactaactct
    26401 gtgagtctgt atggaaatcc aatgctaaat ttatcaagat ttccaacaat ctcatcaaag
    26461 tggatttagc tgactgattt ttgaacctaa ggtttcaaaa atccccacat aacagtacgg
    26521 cggtgcatat ccctctagca agtcttcgac ttgcctctaa cgattttaga gtacagtatt
    26581 actcactatt ctgcgtcttc tgctaaaagt ttaactcgtg tttcttcatc caaaagtggg
    26641 taacctaggc gtttgcgttc tgcaacaaag gttttggcta caacacgggc caagttacgg
    26701 atacgagcga tatagcctgc acgctctgtt acagatacgg caccacgcgc gtcaagcaga
    26761 ttaaaggtat gtgaacattt gagaacatag tcataggcag ggtgtaccaa gccttcttct
    26821 aatgcacgac cagcttcttt ttcaaactta tcaaagtttt caagcaacat ttcttggttc
    26881 gaaatttcaa atgaatattt tgagtgctca tactcaggct ggataaagat ttctccgtat
    26941 tttacaccat cagcccactc gatatcatag acagagtcta cttcttgaat gtaagaagcc
    27001 aagcgctcca aaccataggt aacttccgca gtcacagggc cagttgccaa tccaccgact
    27061 tgttggaaat aagtgaactg agtgatttcc attccgtcaa gccaaacttc ccaaccaaga
    27121 ccagctgaac cagttgatgg gttttcccag ttgtcctcaa caaaacgaat atcgtgctcc
    27181 aaaggattga ttcccaattt ttccaaagac tcaaggtaaa gttcttggat atttgatgga
    27241 gaaggcttca tgaccacctg gaattggtgg tgttggtaga gacggttagg gttttcccca
    27301 taacgaccgt cagcaggacg acgtgatggc tctacataag ctgcattcca tggctcaggt
    27361 ccgatagcac gaaggaaagt gtaaggactc attgttcccg cacctttttc attatcataa
    27421 gcctgcataa gcatacaacc ttggtcattc caaaattgtt gcaaagtcaa aataatttct
    27481 tgaaatgtta atttcttaga cattgtttac tccttaataa aaaataattt cttgcgacac
    27541 gagtctgcct cgtcgattat acgaggcaag acgagttagt actgcgtcta gctcaggcac
    27601 tctagtgctg agcgtggagc agcccgactg taaggaggtc tctgccactg atgcagtgaa
    27661 atgttaattt cttagacatt gtttactcct ttagttttta tatttctttt tcaattaatt
    27721 tctgctgaac aaaccaatct aacaagggaa aagttttttc tgtatttgcc catagatgat
    27781 aagaatcaaa gaccgcttgt acactaccta aattttctac caacttatct actatcaaaa
    27841 aactgagcca atattcataa aaaatacttg catagttctt atcataagtc gaagaaccaa
    27901 aatcattcaa tgaatgccaa ccatacttct tctgaaaaag ttctactaga gattgagtac
    27961 aaattttttc cgcttgaaat tcctcttctg tcaagaaata cttgcgacta atatattcaa
    28021 ccatcccctc ttcgaaccag atataagagt cataaccatc aaaatcatct aaaaaatgct
    28081 ccgaccaatg agctaactca tgtcctacaa tctgtaagag gaaattttca gataaagaat
    28141 gatagtgact ttctattgct tgagtttgct gagaacactc gtagtccatc aattgataca
    28201 aatacaactc tttccaaaca gctaaatcag gcgtcataac cattcgtcta ttatttgtat
    28261 aggctggaac agcgctttcc ctaataatct gtgtagcagc attaaaattt gaccaaataa
    28321 cggcttgcgg taaatcacag actgcaagtt cattctttaa aaaagattga taatctttca
    28381 acttttcagt atttcttact acaaaatcac gaaatgcagc tagttgacta tcgtctttta
    28441 caagataaag gttttccacg tctctccttt ctttcacaca atagactgaa taagcaaaag
    28501 aaccacatct gacaatccta ggttgattta acctaggggc gtcagaaacg cggttccacc
    28561 ctaatttatt acttcattgt ttttgaaaat actacagaaa gcgccagctc attattttgc
    28621 cctacttggc tcccactgtc ccaagctcgc ttgaagaacg ccataagact ctctttcctg
    28681 ctgactatta tatcaaaaat tagaataatg tacaattctt tttatgattt tctagaaatc
    28741 cacatcatca actcgtggag cacccgattg aacagcaatc gtttttaagg tttctctctc
    28801 ctcatgactc agttcaattc caaaacaatc aagattagct tgaatacgag aggttgtgac
    28861 agattttgga agtggtaaaa atccttctgc caagctccag gccaaggcta tctgagcaac
    28921 cgattttccg tgatttgctg ctatttcttg gacttgcttg ctatcaaaca gttctccttg
    28981 tccaaaaggc ccccaagctt ccaataaaat tcccttttca cgacagtaag ctacgacttg
    29041 atcttgatac acacctggcg ccaagcgaac ttgattgacc gcaggaacga tagttgcagt
    29101 ttcaagcaag gcatccaaat gatggggaag aaaattgcta acgccgatag cacggatttt
    29161 cccttcttga tagaggtctt ccatcgctct ccaaacttcc gcattgcgag ttttccatgc
    29221 gtcattttct ctgagcggtt ttgggttcgg ccaatgaatc aaatacaaat ccaaataatc
    29281 caagcccagt ttttctatag atttttccaa agcttgacga gtttgctcat aggtttgctg
    29341 actattccaa agcttggtag ttacgaacat ttcttcacgt ggaactccgc tatctttgat
    29401 tgcttgacca acactttctt cattctgata aatcgccgcc gtatcaatat gacgataacc
    29461 agccttcaag gcttctaaca ctgcacgata ggcttcttct ccatccttag ccttaaaagt
    29521 tccaaatccc aatactggaa tttctactcc attatttaat tgataggtat tcatatgctt
    29581 ctccttctat tttattcatc aattatagca taaaacattt tttaagtagt actatcttct
    29641 gtaaaaaata agtctgtcaa atatctaaca gacctatttt ttcttgctta ttcatcacga
    29701 ctatagtaca gctcatgagc ttttaggcga gtattgagca tctctggtat ggtcacaaag
    29761 gtataacctt gatttttcaa atactcaatg acccttggca aggcattgac tgtcggactg
    29821 tgaatatcat gcatcaaaac gatagagccg ttagctactt gatgctgaat ttctgtcaaa
    29881 atagatgctt catttttact cttccagtcc agactatcca catcccacat gataaagctc
    29941 aaatccaagc tattgcgaat atcatctgta atagcaccat aaggtggacg catgagttta
    30001 gaactagaac ccagcacttt agttagcaca tcctcagtat cagtaatctg ctttttagct
    30061 tcatcaagag agagttgcga gagaatcgga tggctccaac tatggtttcc aacaacatga
    30121 ccttcagatt ttatcctctt caccaagtcc tcattcccag aaacattttt cccaagcaca
    30181 aagaaagtcg ctttaatatc atatttagct agggtctcta atacctgcgg ggtcgttgct
    30241 ggatttggac catcatcaaa ggttagagcg acaacttttt gatgtttctt atcaaagtaa
    30301 gattggtaca aggccgcatc tttttcgagt aagtacgaag attggataac atcaaagaaa
    30361 gcagatactg gcaaggctat ctcttctaaa ttttcaacca caggacttgg ataaaggata
    30421 atctgactat ccttgtaatc aaaattccat gcagacaagt cttggtcaga gaagtttttt
    30481 acaatctgct cactctggtc ttgctctatt tttttatcct ctatgaagga ggtcaactct
    30541 tttatcagct gttccttagc cttactagca tctgaaaaca gttggtcaag tgtaaaaggt
    30601 tgcccatctt ctgttaagtg aacctttcct agactggtct tttcagtctc ttcaatctta
    30661 aaagcaacta aatcatagat ttgtttggtc acattacgat taacgactcc ctttaaacct
    30721 gactcttctt gctctgtata gtagaaaaca agattgtcct tactttctag cttgtcctta
    30781 acatcttgat ttatcagctc cctaacagag gaaatcactt tctccccttg gatagggtaa
    30841 taggcaatca cttcggcttg ccccttacga aaatgcttct tctgatttcc ctcactcaat
    30901 tgatcatctt tctctttttt gagcgattca atcttttgct caaaactttt ttgctggtag
    30961 atcttaaaag caataaatcc gcctaatagg caaatagaaa ttgctaaaat accaatcaaa
    31021 gccaataata catgtctcgt tttcccgtgt ctgccacgtc ccagtctact tttatccata
    31081 tttatatcat aacaaatttg agaaataatt tcaatgatac aatttggcaa tccacaattc
    31141 ctctagcaag ccaaagcatc ttacatcaac tccaacatcc gtatctgtag agattatgta
    31201 gttttctatc tatggaattt ctagtggatt gaaactagaa tagtagacct atacttctaa
    31261 aacattgtta gaaatcgatt tgactgtcct gttcgatttg tcctgttttt atttcatttt
    31321 actataaaac tatgaaaagc taggtcatct gagaagtaat tactatcgac aattgcgata
    31381 gcgtatactg gtgcgatgtg tttgtagctc tggtgggtat caccttcacg ttgacggatt
    31441 ttttcaaggt tttgattaac ctgactgcac agataagccc ataggcgatt gatgaaaaaa
    31501 ttttgatgat gaacctgaat ttcgatgata acttgggttc cattatctaa ctccgccaag
    31561 acgtcgtcta tactagtata gaaatcctgc gctgagtagg gcatggaagg caagacatga
    31621 atatcgcttc cctccaaaat ggtcacattt tttgctggca agtccagcat atcgcgaata
    31681 aattgacaag tcattggtcg ggctaatgcc cggatgtctt agaatcatcc ttttcctcct
    31741 tctatagtga attgaaata
//
LOCUS       DAVKMO010000020        31437 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVKMO010000020 DAVKMO010000000
VERSION     DAVKMO010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31437
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.020"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(1..1189)
                     /locus_tag="VW361_001063"
                     /pseudo
     CDS             complement(1..1189)
                     /locus_tag="VW361_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1563..3530)
                     /gene="tkt"
                     /locus_tag="VW361_001064"
     CDS             complement(1563..3530)
                     /gene="tkt"
                     /locus_tag="VW361_001064"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9744117.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAVLPTFLGGSADLAHSNMTYIKADGLQD
                     KYNPLNRNIQFGVREFVMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQELP
                     VTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQATWHHALTSTTT
                     PTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELVL
                     QGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVIG
                     IDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            complement(3567..4262)
                     /locus_tag="VW361_001065"
     CDS             complement(3567..4262)
                     /locus_tag="VW361_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU9744118.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKATIMTVDPGFAGQRFLESTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            complement(4273..5358)
                     /locus_tag="VW361_001066"
     CDS             complement(4273..5358)
                     /locus_tag="VW361_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEU9744119.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIVGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILRKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            complement(5384..5695)
                     /locus_tag="VW361_001067"
     CDS             complement(5384..5695)
                     /locus_tag="VW361_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEU9744120.1"
                     /translation="MKIVGVAACTMGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            complement(5723..6172)
                     /locus_tag="VW361_001068"
     CDS             complement(5723..6172)
                     /locus_tag="VW361_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9744121.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            complement(6150..6578)
                     /locus_tag="VW361_001069"
     CDS             complement(6150..6578)
                     /locus_tag="VW361_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9744122.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKPPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            complement(6571..8034)
                     /locus_tag="VW361_001070"
     CDS             complement(6571..8034)
                     /locus_tag="VW361_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU9744123.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKG
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFRMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFSELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSAFLTEGDKQRLQAKIQEINYE"
     gene            complement(8563..10899)
                     /locus_tag="VW361_001071"
     CDS             complement(8563..10899)
                     /locus_tag="VW361_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEU9744124.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            11032..11781
                     /locus_tag="VW361_001072"
     CDS             11032..11781
                     /locus_tag="VW361_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU9744125.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTNKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            complement(12074..12688)
                     /locus_tag="VW361_001073"
     CDS             complement(12074..12688)
                     /locus_tag="VW361_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU9744126.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(13423..13692)
                     /gene="rpsO"
                     /locus_tag="VW361_001074"
     CDS             complement(13423..13692)
                     /gene="rpsO"
                     /locus_tag="VW361_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU9744127.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            complement(13833..14462)
                     /locus_tag="VW361_001075"
     CDS             complement(13833..14462)
                     /locus_tag="VW361_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU9744128.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKDQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            15318..15458
                     /locus_tag="VW361_001076"
     CDS             15318..15458
                     /locus_tag="VW361_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU9744129.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            15465..15641
                     /locus_tag="VW361_001077"
     CDS             15465..15641
                     /locus_tag="VW361_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU9744130.1"
                     /translation="MTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENF
                     LSDKEKQLNVRTRK"
     gene            15699..17642
                     /gene="thrS"
                     /locus_tag="VW361_001078"
     CDS             15699..17642
                     /gene="thrS"
                     /locus_tag="VW361_001078"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU9744131.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAHEIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(17691..18665)
                     /locus_tag="VW361_001079"
     CDS             complement(17691..18665)
                     /locus_tag="VW361_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9744132.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVVEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(18658..19335)
                     /locus_tag="VW361_001080"
     CDS             complement(18658..19335)
                     /locus_tag="VW361_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9744133.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            19491..20564
                     /locus_tag="VW361_001081"
     CDS             19491..20564
                     /locus_tag="VW361_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU9744134.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            complement(20655..20957)
                     /locus_tag="VW361_001082"
     CDS             complement(20655..20957)
                     /locus_tag="VW361_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744135.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFTFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(21026..21463)
                     /locus_tag="VW361_001083"
     CDS             complement(21026..21463)
                     /locus_tag="VW361_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU9744136.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            complement(21539..22381)
                     /locus_tag="VW361_001084"
     CDS             complement(21539..22381)
                     /locus_tag="VW361_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU9744137.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRHGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDGKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            22493..23143
                     /locus_tag="VW361_001085"
     CDS             22493..23143
                     /locus_tag="VW361_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU9744138.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNIDIAKQLYVEKIN"
     gene            23320..23997
                     /locus_tag="VW361_001086"
     CDS             23320..23997
                     /locus_tag="VW361_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU9744139.1"
                     /translation="MVVGIAIASGYLNSRLDKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKATIITYPVTFLIYTFAIKKWKASQE
                     GSPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVRYIE
                     GNSNKEY"
     gene            24099..24512
                     /locus_tag="VW361_001087"
     CDS             24099..24512
                     /locus_tag="VW361_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744140.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFECLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            24586..24947
                     /locus_tag="VW361_001088"
                     /pseudo
     CDS             24586..24947
                     /locus_tag="VW361_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014307.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(24986..25429)
                     /locus_tag="VW361_001089"
     CDS             complement(24986..25429)
                     /locus_tag="VW361_001089"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU9744141.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDVEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(25459..27681)
                     /locus_tag="VW361_001090"
     CDS             complement(25459..27681)
                     /locus_tag="VW361_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU9744142.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVYFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMIELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            28675..29304
                     /locus_tag="VW361_001091"
     CDS             28675..29304
                     /locus_tag="VW361_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9744143.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(29427..31319)
                     /gene="pepO"
                     /locus_tag="VW361_001092"
     CDS             complement(29427..31319)
                     /gene="pepO"
                     /locus_tag="VW361_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU9744144.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVATVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         9327 a         7094 c         5732 g         9284 t
ORIGIN      
        1 agaatcccaa agaaagattc catcataccg ttatcttggc tgtttccctt gcgtgacata
       61 gatgcttgaa ttcccttacc ctcaagaaac tgatgataag aatcgtgttg atattgccag
      121 ccttggtcac tatggagaat cgtattctcg tagtgcttct ctgtgaatgc ctgttccaac
      181 attgtttgta cttgttctaa gttgggtgaa gttgaaagat tataggcgat aatttcgcta
      241 ttaaagccat ctaaaactgg tgataagtaa agcttttgag tacttgctgg aatggcaaat
      301 tctgtcacat ctgtgtagca cttttccatt gttttagagc cttcaaattg gccttgaatg
      361 agattctctg ccttcttacc aacgtctcct ttatgagaag aatattttcg tttctgtcgc
      421 attttagctt gtaaattgag tactttcatc aagccttgaa ctcttttatg atttaccaga
      481 taaccacgat ttcttagttc taaataaatc cgacgataag cataatttcc cttgtgttcg
      541 ataaaaatgg attgaatttc agctttaagc tcttggtcct tatctggttt atctagctgt
      601 ttcaagtgat agtagtaggt cgaacgagct agtttaatgg cttttagaag aagatctaac
      661 gaaaactcag tcattaattc ttgaacaatt tctgtctttc ttctttctct ttttcctcct
      721 tcaatcggag ttctcttaac ttttttagga tggcattctc cgctctcagg tactcatttt
      781 ctgcttgaag acgttctagt tctgtcctct cttcaggtct cttttttggc ttacgtccca
      841 ttttaggtac tctccctctt gttttctcaa caatagtata cccgtttttc ctgtattgtg
      901 ctagccagtt aagaagtatc gtacgacttg ggagaccgta ttcaagagaa actctatctt
      961 tagtccagcc ttcatgtcag actttattac tcatttcttg ttttaaatca ggagaatagt
     1021 aacgattttt cccttttttg acgaactcta ttccgtaacg atcaatcaat ttaatcatgt
     1081 acctaagatt agaattattt atcccaaatt tatttgaaag cttctctaag ctatatcctt
     1141 gttttctaag ttcatagatc tgaactttat catcataagt taatttcata ataaaaacac
     1201 cccaaaagtt agattttttc tgtctaactt ttggggtgca gttcatcatt tcaacatcct
     1261 atactatgag ttttttaatt ttagagacct tctctctagc tttcaaaaaa cttacaatat
     1321 cctaagtcaa tctgtggatg ctgtgtttat tgattaaaga aactatctag atcagtagca
     1381 aagtgattag cgtacttcgc aaccgtttca gggtatactc tattgtgtat actatctact
     1441 ataactttcg tagataaatt attacattct cattatagtt tttaaataac caatcatctg
     1501 attagtgtct atcactacat ctgctagtct gacaacagct gtatcttcat tgtaattggt
     1561 ttctataggg acttaacttg agcaacgata ttctctaccg taaatccata attatcaatc
     1621 acagtctgag ctggggcaga cgcaccgaag atgtcaatac cgatgaccgc gccatccaaa
     1681 ccaacatact tgtaccaact ttgggtcgct gccatttcaa tggccacacg acgacgagtc
     1741 ttagatggta aaatgtcttc cttgtaggta gcatcttgag catcaaatag ttcggttgag
     1801 ggcatagata ccacacgtac tttaccacct tgtaaaacca attccttagc agctttgata
     1861 gctagattga cctcagatcc tgtagcaatg ataatagtat caaatcccgg ggtatcatac
     1921 acgacgtagg ctcctttagc gaccttacca aagtctgtcc cttcttcaac taccaagttt
     1981 tgacgggtta agacaatgac agttggagtg gtggtactgg tcaaggcatg atgccaagtc
     2041 gcttgagttt cacgggcatc cgctggacgg ataacagtca agtttggcat tgagcgtaaa
     2101 cctgccaaat gttcaactgg ttcatgagtt ggaccatctt caccaacggc aattgaatca
     2161 tgggtaaaga cataagttac aggcaactcc tgaatggctg atagccgaat agcagctttg
     2221 acgtagtcag agaaaacaaa gaaggttccg ccataaactc gtaaaccacc atgaagagcc
     2281 attccattga ggattgttcc catgacaaat tcacgtaccc caaactgaat attgcggttt
     2341 aatggattat atttatcttg taagccatct gccttgatgt aggtcatgtt ggagtgagct
     2401 aagtctgccg atccacctaa gaaggttggt aaaactgctg ctgtattaat agcatcttgg
     2461 gacgaattac gagttgcttg agagaagcca ttctcataga cagggaagtc tttttcagta
     2521 atggttacag gggattttcc agctacaata gcgtcaatct cactagcaac ttcgggataa
     2581 gcaaccttgt aatcagacac caaactagcc caagcatcgt atgcctcctg accacgatcc
     2641 gctacatttg tcttgaaatc agaatatact tcctctggta cttcaaatgg atcgtaatcc
     2701 catcccaaaa acttacgagt tgctcctgtt tcttctgctc ctagtggtgc accatgaaca
     2761 gcatttgtac cacttttatt gggtgagccg taaccaatta ccgttttcac ttcaatcaaa
     2821 ctcggcttac cagaaaactt ggccgtctca attgctgtag aaattgctgc taaatctgtt
     2881 ccatcttcta ccagaactgt atgccaacca taagcatcgt aacgggcgcg aacattttca
     2941 gagaaagtat ctttggtctc accatccaag cagatatcgt tggagtcgta gaggacgata
     3001 agcttatcta aagcttgatg acctgcataa gaagccgcct ccgcagacac tccttccatg
     3061 aagtcaccgt ctccagcgat aacataagta taatggtcaa aaataggaaa accatctttg
     3121 ttgtacttag cagctaaaaa acgctctgct tgggcgaaac caacggcagt agaaatcccc
     3181 tgaccaagcg gaccagatgt cgcatccaca ccagacgtat gcgtcacttc aggatgacca
     3241 ggtgtcttag atccccattg ccggaaattt ttaatctcgt ccatggatac atccttatac
     3301 cctgttaaat gcaagagagc atacagtagc attgatccat gacccgcaga caagataaag
     3361 cgatctcggt taatccagtt tggctgctca ggtgtaattc taaggtgctt tgtaaatagg
     3421 ctataagcca ttggcgcagc acccatgacg attcccgggt gaccagaatt agatttgtta
     3481 atagcatcta cgccaagaaa acgaatggcg ttaactgatt gtagtgacat atattcctcc
     3541 taactaataa atttcttctc aaaccattat ttgattggca ttgtttttcc ggtcatttct
     3601 tcgtaatctc tagaacagat atcccaggct ttggcaatat cgtcatccaa accaaataat
     3661 ccactgcgac ctataacata aatatctggt cctgccacat caatttgttt gaaagtctta
     3721 cgactcgaag aaccatccat ctcaatgatg tagtgataac cattctgaac tctaagctga
     3781 cggagttctt ggattttata caaggtagac tccaaaaagc gttgtcctgc aaaacctgga
     3841 tctacagtca taatagttgc tttgtcaagt aaatcaatgt agggaaagat tgtagaaaca
     3901 ggtgtttcag gattaaggac aacaccagcc tttagacctg catcatgaat tttatcaatc
     3961 aaacgaaaag caagaccatt cagaacttca gcatgaatac aaatatactc acattgtaaa
     4021 tcgagaactt gatctaccca aaaggttggg tctgtgacca tcagatgaac tgataaaggt
     4081 gtgtcactaa ttttttgaac ttcttgaatg aaccaaggag acaaggtaat attgggaaca
     4141 aaatggccat ccataatatc gatatgataa gatgctactt tatcattcaa aaaagtaatc
     4201 tgctctttga atttgtccaa atccatggtc atcaaagatg gtgaaaattc aattcttgac
     4261 atcgttaccc tcttacaaaa tttcaatatc tgacaaatca atctcttctt caacagtcat
     4321 aactggttct gtatgtttta ttggttttct caaaatcgcg tagacaagtc ctgtgactac
     4381 aatgttggct aacaaagcac aaataccagc tactggacga gtcatggttg gtaacataag
     4441 cactccacca aatggcacgg cagaatcagc acccattgtc aaagaaacag caccaccaac
     4501 agcaccaccg atacctgttg caatgagacc tggaaccaag ttattcataa caatcggaat
     4561 tacaccttca acaatattga caatccccat aggaacagcc gatttcaatg tttcgatttc
     4621 ctcttgagta tagatatttt ttttgagtaa tttcgcgata aaataggcca atccaaatcc
     4681 aactggtgta gcagtattca ccaattgcaa agcagtcaat ggttctttca caccttcagc
     4741 ctgtaaagtc aacacaaacg catagactgt tttattaagt gggccaccaa agtcaacagc
     4801 actgagaact ccaataactg cccccatcaa accatttgaa gcacttccca agctttgtaa
     4861 taagctcgtc aaccagttgg taaaggctgc gataggcgcc ccaataatat aaatcataat
     4921 caaactactt accaaagagg ctacaaaagg aataatcaag gttggcatta aacctttaat
     4981 ccagtttggt actttgacct ttttaataat cgcttgaacc aagaaaccaa ctatataacc
     5041 tcccaagata ccaccgataa accctgaacc aacagaattg gcaattagac caacaacaaa
     5101 acctggtgca atccctggct taccagcaat cgagtaagac aaacctgtag caataacaac
     5161 tggcaagaga ccaagggctt taccacccat agttgctaaa gcatcccaga tagtgaattt
     5221 tcctgctaca agagcgtcag gaacaccacc ccccattgct aaaccaatgg caactaagaa
     5281 tcctgcacca caaacaattg gaatcatata ggaaatggct gtcaataagt gaccttttaa
     5341 gtttaagtgt ttcaacatat attttctcct taaatatttt cagttatttc gtaacaatct
     5401 caacagcttt agcaatcagt ttattgggag atttgactgc cacttctgtt ggaaccttga
     5461 taatcttttt accctcaaag cgttccatac cagaaatctt aacatcaact gctaaaataa
     5521 ctacatccgc tgcatcaatc tgctcttgac tcaattcatt ttctacccct attgtcccct
     5581 gagtctcaac atgaatcaca tgtccagcta cctttgcggc attctctaat ttttcctgtg
     5641 caatataagt gtgggcaatt cccatagtac aagctgcaac accaacaatt ttcatacgga
     5701 taccctccaa aattttttct tattaacaaa aagctgcaat cacatcatca gatgtctgag
     5761 cccgaactaa tttggcaaca acttcgtcat taccaagttt tcgagcaaag agtgataagg
     5821 tcttcaaatg ctccctagca gcttctgtat catcaccaac tgcaaagagt acaattactt
     5881 tgaccccttt cccatcaatg gtctcccaag gaatctcatt gtgatttata gctatgacta
     5941 cccccgcctt ctccacagca gaactcttgc tatggggaat agcaatataa ttcccaatac
     6001 cggtctgtcc ttctgcctct ctctgataaa gaccttcgat aaattggtct ctatcagaca
     6061 cataacccgt ctcaaccaat agttgagcta atgcctcaaa aacctcttct ttgctctgca
     6121 tctgtaaatc cgtctggatc agactcacat taagaatatc tttgatttcc atatattatc
     6181 tcccgtaatt cttcttttgt taactgtttt aattgattta tgaatgattc atctgctagt
     6241 cttctcatca atgttttaat acatgacttg tcctgtgata ctgcaatggc caaaccgata
     6301 ataaggtcaa cacactggat atccttcgac cattctctga taggtggttt taatctagta
     6361 atcactaaga catgatgttg aaagtttcct tcacaatgtg gtagaagaac acctttagca
     6421 acctctatac ttccctgtct ctcacggtaa tatagaagct cttctatttt ttctgtatct
     6481 tcagaaacaa gaaggctgat ttgatttgct aattctttgt aggcttcttg acgattttga
     6541 acagatatat ccataaggac aagcgaaaga ttattcatag tttatctcct gaatttttgc
     6601 ttgaagacgt tgtttatcac cctcggttag aaaagcacta actaggacaa acgggacact
     6661 tgctggttcc tgcaaagcta ccgtcgtcac aatgaaatct aaatctggat atagatttat
     6721 cagctcatct aattgatgat aagcaactac atcaataata tccaattcag aaaattgctt
     6781 ttctaatcgt gctcgtaaaa gctctgaagt tccgacacct gatgtacaca tcactactgt
     6841 ttttagagga cgtgctcgct tttcttgaaa ccgtgcaaaa tataagacta gaaaaccaat
     6901 ctcgtccaga ctcaaggacg caaaaccaaa tactagactc acttctttag aaatagttgt
     6961 taactcttta accagattag gataggttaa aagaatttgt gataaaagac tattcttaat
     7021 ctgtactcta ttatctaatc tcctcagtaa gggactgata tgactcgcca agtcaacaaa
     7081 gtcaggatct gtcgtttcaa tctctctatt gtccatacac atacggctaa aatagtaatg
     7141 agtgacatct aaaactcgct gagaaaaagg aagcttcccg gaagaaaatg gtttttgcaa
     7201 tctcgaagat acaacgtatt gataaagata gtcaatctca actgcatcaa ccttcatcct
     7261 aaaatattgt tcaatttctt gaataatttt ttgacagaca ctgtaaattt tctcatcaac
     7321 aatagtaggt tttgaaggtg ctacaacatg aatactagta ctacgacgat tcctactgat
     7381 aaaaatatac aggtgagaga aaatatttat attatatgga tagggaatgt ttacccccaa
     7441 ttctctctca agtgtaatca gtaatcccaa acaaaagtga gcaagttctc cgtcaagagg
     7501 ctgaacctta ttctgtgtaa tttgctctaa atccaactga ttaaacattg gcagtagatt
     7561 tagaatggct gaacgaattt gagcctcatc cccatcaata aaaagctttc gttgtctcat
     7621 ttttaaatct aacccataaa ttgctagact ctcttgtaat atctgacgat cttttagtac
     7681 tactgactcg cttacgtaga attcctctcc taaatcataa atagaatgtg gcttaggagc
     7741 agtcaacaag agacgttcta gtaatttttc acgccttact tcaggatcaa aagcctctgt
     7801 aaaattccca tcaacgtcca cgagggaact tcttggattt aatttgaaac ctctgccttt
     7861 ttcagataaa atgaatgctt ctaccggaca atctttgttg attcccttga caaggcgata
     7921 aaccgtttta tcagagcaat ttaatttttc tcccaatact ttagcagata tataatcctt
     7981 actatctcgc aaaaggagca acaacgtttc catttgttct tgttttctag acacgataca
     8041 cctcctttat gattccatta tatcgctttc aaaaaataat atacttcgca ttttgtcctt
     8101 tgcaatggac atttttgttt ttatcaaaaa tatgatatca aatagaacag aacctcacta
     8161 tgccaaaatc attttacctt ttcttcataa catctatttt agttgaaata tttaagttgc
     8221 ttttcgtatt tgataagaaa taaaccaaac gattttctaa taaataacac tatgttccat
     8281 ttaacaatag atagcatctt cattttcaaa ctaccaactt atccgaccat ttgttctagc
     8341 aatagaagag agttaaaatt acttcaatct gtcgctttct ctttcttaca tcaaacttca
     8401 aatagtctaa ctacagatat ttgaatctat tacctcaatc caagcaggct tgagaatcac
     8461 tcttgggttc accgatagat gatcggcacg taggccttgc acatcagatc tacgatagat
     8521 ccatcgtata aaaaactgca atccacagat tgcagtcttt ctttattttc tagcttgata
     8581 gcgactagtc aggatgaaaa tcactgtaaa gaccaacatc atgacaccat aaacaggcaa
     8641 cgtttgttct gtcaaggttg aaatttcaag cagtttttgg attcttggga agagagctgt
     8701 ggctaggaag cctcctactg accagacaat caagaggact cgccatagag tgaatggcat
     8761 gcaggctcta aatacggata agaaaccaat tgaccccaag agataataga ggagagttga
     8821 gatttctaac tcagaccaac cttgactcgt tccaaagatt ttcacaaaaa gaacgctaaa
     8881 cacgaccatg agggcacttg gtagggcacg aagcatggat cttctgagga agtttggctc
     8941 gacaggtttg atatttcgct caaaagtcaa aacgaatggt gggaaacctt ccacaaactg
     9001 gtcaatcatg gtaatctgga ttggaatgaa ggggaaaatc aagatccatt cagaccgacc
     9061 tagtaaagca ctggcgatac agataactgc gagcaagaat gagtagatgg tctttatcaa
     9121 gaaaatcgga gcgatgtggg caatgttatt gaccacacga cgaccttcaa aaagaatctc
     9181 aggaacatca ttaaagtctg agttcaagag aaccaggttg gcaatctgac gggttgctgg
     9241 atccccctcc gccattacga tagaacaatc cgcctcacga agagccagga tatcattaac
     9301 tccatcccca gtcatagctg ttgtatgacc cgcttttttc agcgtttgga taatgagttt
     9361 cttttgatga ggggaaacac gtccgaaaat agctgtctcc tccgccatgg ccatcaattc
     9421 ctcatcggtg atttttgagc aatctacata gctgtgatag tccgcaaaac cagccttctg
     9481 ggcaatgctg gacaccgtaa ctggattgtc accagagata atcttgagtc ccacctcctg
     9541 agaacggaga tagtccagcg tctctgctgc tccctctcga atggggtcca agatttccag
     9601 caaggctaga gcctgaatat cagatggttt ctgtggtttg tgatggtcta atttctcctg
     9661 actgagagct aagaccaaga cacgtgatcc tctctccaag gcctccctgg cttctgggac
     9721 ttcagaatcc agcaacatct caggtgcccc taagaaaact gtccccaagc cttctaactc
     9781 catagccccc cacttgcggt cgctggagaa gggaagattg gaaatcatag gataagcaac
     9841 atctcccaca aaacgctggc gaatggcttg ggcagttgga ttcttatcct cactatgggc
     9901 catatagctg gtcaggatgc tggcaacagc ctcttcaccg taagtttccg tcagtggaag
     9961 aacagcctcc acctgcatct ttccttgggt gatggtgccc gtcttgtcca gacagagcat
    10021 atccacgcgc gccaaggtct caacagagta catctcctgc accaagacct ttttcaagcc
    10081 caacttaatc actgcagtca agagcgaagt aatggtcaaa agggcaattc ccttaggcaa
    10141 cattcccaaa agagctgtcg acgagtttac aacggatgac ttgagaggca ggccttttaa
    10201 aagcaaggct tccagcaaga gagccagacc aaagggaatg ataatcttcc cagtaaaacc
    10261 agccaacttg tccagcgatt tcatgatacg ggagttgatg ggtttaacgg tcttagcctc
    10321 aagcatgagt ttggcagcat agttgtctgc accgacatgg tgaacttgag ataaaactga
    10381 cccactggct aggaaacttc ctgacaaaag taagccgtca acttcctttt gcaccaaatc
    10441 actttctccc gttaacatgg cttcattgac ttccgcaaag ccttccaaaa ccaaggcatc
    10501 actaggaatc tgctctcctg cagacaaacg aatgacatct cctagcacta attcttcagg
    10561 attaagagca acttcctgac catcacggat ggttttgacc ttttccttgg tcatgagatt
    10621 gagcttgtcc accatgtgtt tggctcgtag ctcggtcaca atcccagaaa aagcgttaaa
    10681 gcagataaca gcaaagaaga ccagattgct ccaagcctgc acaaaggcaa gggccaaagc
    10741 aatggcaaag ttcaaagcgt taaaaagggt aaagacattt cgtttaacga tttgccaagt
    10801 gctggtactg gctgatgcgg taaagtcatt gaccaaaccc tcagcctgtc tttccttgat
    10861 ttctctttgg gttaatccca taatcttatt tttatccata aattctatta tatcattttt
    10921 tttaacagaa ttctaatttc atcccaaata tgcatctagt caagggaaaa gtttgccagc
    10981 cctcctttga taaggtataa taataacaag aaaacaatcg aaggagatcg catgttttat
    11041 acttatttgc gtggattagt tgtattgctc ttatggtcca tcaatggcaa tgctcactat
    11101 cataatacta ataaaattcc taatcaagat gaaaattata ttttagttgc gcctcaccgt
    11161 acctggtggg atcctgttta tatggccttt gcgaccaagc caaaacagtt catctttatg
    11221 gcaaaaaaag aactctttac caaccgtatc tttggttggt ggattcgtat gtgtggcgcc
    11281 tttcccatcg accgtgaaaa tcccagcgcc tcagccatca aatatcctat caacgttctc
    11341 aaaaaaagtg accgctctct catcatgttt ccaagtggta gccgccactc aaacgatgtc
    11401 aaggggggcg cagcactgat tgccaaaatg gccaaggtcc gtatcatgcc ggttacctac
    11461 accggtccca tgactttgaa gggcttgatt agccgtgaac gtgtcgatat gaactttgga
    11521 aatccaatcg atatctcaga tatcaagaaa atgaatgatg aaggcattga aacagtcgcc
    11581 aatcgtattc aaacagaatt ccaacgtctg gacgaagaaa cgaaacaatg gcacaatgat
    11641 aaaaaaccaa atccactctg gtggtttatc cgcatccctg ccctcatcct tgctattatc
    11701 ctcgctatcc taaccatcat ctttagcttt atcgcaagct tcatctggaa cccagataag
    11761 aaaagagaag aacttgcata gaagaaatga accttggcca aacagctaag gttttcattt
    11821 atatagtaga ttggaactag aatagtacac ctctacttct aaaacatttt tagaaatcga
    11881 tttgactgtc ctgatcgatt ttgtcctatt cttatttcat tttactatat ttataagaat
    11941 cccctaatca aatcaaaagc cactctacaa tagagtaact ttaagattgt ccatttatac
    12001 tcaatgaaaa agccctctga aaatcagaga gctgatttga gctcaggcta aaatcctagt
    12061 gaaacaaaaa aatctacacg atcagaaaag tctctatcgt gccattttca tacatgatgt
    12121 atagtccaag tagaatgaat actaagggca caatgattcg ctcgtatttt tcaattgtct
    12181 cgaatattaa cggaatagag gataacaccc tactaatctc gcaaaagata attatgccga
    12241 ttacaaacac aagcaaggcc acgagggtct gtgaccaatc taacgaagca aaataaggta
    12301 tatagatacc taaattatct ccgccagacg caattgtcag caatgtaact gtccaaaaca
    12361 gttgatttgc cttgctttgt tctaatcttt caataatttc ttcctcttct tcttccgcat
    12421 cttctccaac aattgcaaag cgaatcccta aatagatagg gattaaacca agcaatccaa
    12481 ccatccattc ttcaggcacg aaattaacga cataagcagc aactaaactc gcccctacaa
    12541 gtaagcctgt gcctagatat tgccccgcat aaatatgcca tttctgttta ttctgtgata
    12601 gctgtgcaaa taaaataatt aaaataatta aataatcgat actggtggaa atataaacac
    12661 caatagcaga tatgattgtc tgtcccataa aaaaaacctc ctgtattagt cagtaataaa
    12721 tcagcagatt ttaggagagc acagacacat taatttagct atcgctagtg ggtaatgtcg
    12781 aacgtaggaa agcattttac tcctcctcaa aacgtagtta caaagtaatt tctaactgga
    12841 attcagtgac tacttccatg taaagtataa catactatac tttactttgt aaagagtggg
    12901 ctcttctagg gggcttgcat acagctactc ggcttgaaaa gccgagtaac tgcgcacctt
    12961 tatggtgtaa ttagctgata ccgtttgagg tttttgtagt ctccaaaatt gttaccgata
    13021 aaacctcaat aaaaaagccc tctgaagtca gagagctgat ttgagcccgg gctaaaatcc
    13081 cagtgaaaaa gatgaaactc cttgtgctca tcgaacactg tgtcatttcc ctattttcat
    13141 acggattttt gacgccctta gcatcatgat tcttgctaga taaatcgttt atagactagg
    13201 cgacgaggcg aagatcgtac gaaactttca gtgaaacaaa aaaaatctcc ccgaagggag
    13261 aaaagctggt ttattttacc ttacagtgct aggaaccgta accaaagatt atacttgagt
    13321 atatcgaggt aaggtgacaa cgcaaaaaag ctacccaatt tagagtagct tcattatcaa
    13381 gatatgctca attgaacacg gcctaagcac ttgtatcttg aattagcgac gaagtcctag
    13441 agagttgatc aactcacggt aacggttaac gtcgttttta cgcaagtatg caagcaagtt
    13501 acgacggcga ccgatttttt tcatcaatcc acggtaagta gcgtggtctt ttttgtgttg
    13561 tttgatgtgt tcgttaaggt ggttgatttc ccaagtaagg acagcaactt gaacctctac
    13621 tgaacctgta tcaccttcgt gacgtgcata ttgtgcaatg atttcatttt ttttctcttt
    13681 tgagattgcc atgatgtttc tcctttttat ttggcttcat ccgagtgaca ggttggcatg
    13741 cctgtaacca agaagaagtt atttgtcttt acgacaatcc ctattttacc aagatttaaa
    13801 ttttctgtca aacattaata ctctcatagt tattattttt caagtaaaga gatacgttct
    13861 tttatatgat gacctttttc aagttcatct accaatccaa tagcataatc tgcataacta
    13921 atctggctta ttcctttttc attagtagta aaaatttctc ctgctagaat gtagtttcct
    13981 gttttttcac catcgggaat aaaatctaca gcaggactga caaaagtcca gttgagatta
    14041 ttttttgtac gaagaagatc caattcatcc gcttgatctt ttgctagtga cttaaattct
    14101 tcaggaaaat cagacgtatc taaaagtcgt gtcgtttttg tttcatctat ataaagactt
    14161 cctgctcccc ctacaactag aaaacgtgtc tgtgttccag caagaagctg attaaatagt
    14221 tcgattgatt tgctgtggag cggtagcgta tctggtgtat aagcaccaaa cgctgaaata
    14281 acagcatcaa atccagtaag atcatctttt gtcaactcaa ataaatcttt tttaataata
    14341 gactcagctt gacttttgtt ttcagaacga acaatagccg ttacttcatg tcctcgtttg
    14401 actgcttctt caacaattgc tttccccgct tgtccatttg ctgcaataac tgctagtttc
    14461 attttttata cctctcttgt tgtaattatt ttagttacaa caattgtgac acttttaata
    14521 atcaatgtca atagtcttgc ttaattatta tcaaaatatt tctaccaaga aaactaacca
    14581 tgattctagt gaaaaaaatc ttctttgtca acaaatttac tttcttgttt taaatatgct
    14641 ataataatca tagcaagaga tctaagttgt ctgttttttt aaaacgaggt gattatcatg
    14701 cgtagattct attcccatct cccctactat ctggtcatat tattctttta ttggccactt
    14761 tatgagttgt tcttgctagt tgtttctgac ccccttacac tatataaaca atcttctctt
    14821 ctttacacct ctggtaatct tgattgtatc gttactctat agctaccgtt tccgtttctc
    14881 actttgatgg ttagttggta acggactgct cttttacttt actatcataa cctttggtga
    14941 gtttatacta atttacttgc taatctatga aacagttgct ctggtcggca tggattctgg
    15001 tattagcatc aagcatattc tacaaaaaat gaaaaacaaa aaactttcac aaaatccttg
    15061 aaaaatctca caatcatgct ataataatcc atagagacaa gtcacttagt ccctttctac
    15121 tagagagtgc gtggttgctg gaaacgcata ggaagtctaa actgatacta ctcttgagtt
    15181 ttttatgaaa acataaaacg gtggccacgt tagagccaat cagaggtgtc cctctctttt
    15241 gaggtacata aatgaaggtg gaaccacgtt gcgacgtcct ttcgaggatg tcgcattttt
    15301 ttattaggat actaattatg gagttgcaag aattagtgga gcgcagttgg gcaatccgac
    15361 aagcttatca cgaactggaa gttaagcatc atgatttcaa gtggacggta gaagaagacc
    15421 tcttggcttt atctaatgat attggaaatt tccaatgact ggtgatgaca aagcaaggac
    15481 gctactatga tgaaacaccc tacacactgg aacaaaaact ttcagaaaat atctggtggc
    15541 tattagaact ttctcaacgt ttggatatag acattctgac ggaaatggaa aacttcctct
    15601 ctgataaaga aaagcaattg aacgttagga ctcggaagta gtctgctgat aaaaaatcaa
    15661 tgcttagaaa ctatgaaata ataaaaaagg agaacatcat gattaacatt actttcccag
    15721 atggcgctgt tcgtgaattc gaatctggcg taacaacttt tgaaattgcc caatctatca
    15781 gcaattccct agctaaaaaa gccttggctg gtaaattcaa cggcaaactc atcgacacta
    15841 ctcgcgctat cactgaagat ggaagcatcg aaattgtgac acctgatcac gaagatgccc
    15901 ttccaatctt gcgtcactca gcagctcact tgttcgccca agcagctcgt cgtcttttcc
    15961 cagacattca cttgggagtt ggtccagcca tcgaagatgg tttctactac gatactgaca
    16021 acacagctgg tcaaatctct aacgaagacc ttcctcgtat cgaagaagaa atgcaaaaaa
    16081 tcgtcaaaga aaacttccca tctattcgtg aagaagtgac taaagacgag gcacatgaaa
    16141 tcttcaaaaa tgacccttac aagttggaat tgattgaaga acactcagaa gacgaaggcg
    16201 gtttgactat ctatcgtcag ggtgaatatg tagacctctg ccgtggacct cacgttccat
    16261 caacaggtcg tatccaaatc ttccaccttc tccatgtagc tggtgcgtac tggcgtggaa
    16321 acagcgacaa cgctatgatg caacgtatct acggtacagc ttggtttgac aagaaagact
    16381 tgaaaaacta ccttcaaatg cgtgaagaag ctaaggaacg tgaccaccgt aaacttggta
    16441 aagagcttga cctctttatg atttcacaag aagtgggaca aggtttgcca ttctggttac
    16501 caaatggtgc gactatccgt cgtgaattgg aacgctacat cgtaaacaaa gagttggctt
    16561 ctggctacca acacgtctac actccaccac ttgcttctgt tgagctttac aagacttctg
    16621 gtcactggga tcattaccaa gaagacatgt tcccaaccat ggacatgggt gacggggaag
    16681 aatttgtcct tcgtccaatg aactgtccgc accacatcca agtttttaaa caccatgttc
    16741 actcttaccg tgaattgcca atccgtatcg ctgaaatcgg tatgatgcac cgttacgaaa
    16801 aatctggtgc cctcactggc cttcaacgtg tacgtgaaat gtcactcaac gacggtcacc
    16861 tattcgttac tccagaacaa atccaagaag aattccaacg tgcccttcag ttgattatcg
    16921 atgtttatga agacttcaac ttgactgact accgcttccg cctctctctt cgtgaccctc
    16981 aagatactca taagtacttt gataacgatg agatgtggga aaatgcccaa accatgcttc
    17041 gtgcagctct tgatgaaatg ggcgtggact actttgaagc cgaaggtgaa gcagccttct
    17101 acggaccaaa attggatatc cagattaaaa ctgcccttgg aaaagaagaa accctttcta
    17161 ctatccaact tgatttcttg ttgccagaac gcttcgacct caaatacatc ggagctgatg
    17221 gcgaagatca ccgtccagtc atgatccacc gtggggttat ctcaactatg gaacgcttca
    17281 cagctatctt gattgagaac tacaaggggg ccttcccaac atggctggca ccacaccaag
    17341 taaccctcat cccagtatct aacgaaaaac acgtggacta cgcttgggaa gtggccaaga
    17401 aactccgtga ccgcggtgtc cgtgcagacg tagatgagcg caatgaaaaa atgcagttca
    17461 agattcgtgc ttcacaaacc agcaagattc cttaccaatt aattgttgga gacaaagaaa
    17521 tggaagacga aacagtcaac gttcgtcgct acggccaaaa agaaacacaa actgtctcag
    17581 ttgataattt tgttcaagct atcctagctg atatcgccaa caaatcacgc gttgagaaat
    17641 aagagtctag cataaaagcc tccaatctgg aggctttttc tcatctattt ttactcaagg
    17701 actaagttca cttgagcaaa ctgaatccgc actgtcgttc cttttccgac ctcagactcg
    17761 atacgaatct ggtgccccag ttcttcagaa attttcttag atagataaag gccaagtcca
    17821 gaggactgct gggtcaaacg gccattgtat cctgaaaagc cacgttcaaa tactcggagg
    17881 acatcactgt tttttatccc gattcccgta tctttgatac aaagctcttg gtcatccata
    17941 taaatctcca gaccaccttc cttggtgtac ttgagactgt ttgagatgat ttgctcaata
    18001 accactagca gccacttttt atccgtcacg atttctttat caaggtcatg tagattgaca
    18061 tttaagcctt tttgaataaa gaaaagagca tatttacgaa ttatttcctt gaccaagtcc
    18121 tcaatttgaa cctgctttaa gagcaaatca tcatggaaac tttctaaacg caggtactgt
    18181 aaaactaggt tggtatagga gtcgattttg aaaatttcct gttctagctg ctgcttcagt
    18241 tggcggtcga ccacttctac aactaagagt tgactggctg caatgggggt ctttatctga
    18301 tggacccaca aggtatagta atccagcaaa tccgtcagtt ttctttctgc ttttgacctc
    18361 tgctgataga gttccatctc acgcgcttct aatttttctg ctaaagctat ttccaaagga
    18421 gacttggctt ccctctctcc atagagaagt tcctggcgat agacctgcgt ttccaccaat
    18481 atgtcccaag tgaaaaataa gatggttaca aagcaacaca agaagaaaaa gtagaggaag
    18541 taaattccta gactggcaaa taaaaactga aagagtaaga caagaaatgc caaagaaagc
    18601 agatagataa aaagacgact acgggagcgc agataggcta gaaaaaattg tttccaatca
    18661 agcatgcttc aatccgtacc ctattccttt cttggtctcg ataaatccta ccaatccctg
    18721 ctcctccaac tttttacgca aacgagccac attgacagag agggtattat catcaatgaa
    18781 aaagtcactg ttccaaagtt cccgcatcag gtcgtcacgt gctacgatgt tgcctgcatg
    18841 ctcaaataac acgcgtaaaa tctggaattc attcttggtc aaattcaaga cttgcccttg
    18901 ataatgtaaa tccatggatt tggtattgag gataacacca gcatattcca gcaaactctc
    18961 atcacgccca aactcatagg aacgacgcaa caagccctga accttagcta aaagaacctg
    19021 ctggtcaaaa ggcttggtca caaagtcatc cgcccccata ttgattgcca tgacaatatc
    19081 catagcctgg tctctcgaag aaagaaacat gataggtacc ttggaaatct tgcggatttc
    19141 ctgacaccag tgataaccat taaacaaggg caaaccaata tccatgagga ccagatgagg
    19201 ttccgactga acaaatagac tcaaaacttc cataaagtct tctaccagga ccacttcaaa
    19261 tccccattca gagagcattt tcccaatctg ttgacgaatg acctgatcat cttctattaa
    19321 taaaatcttg tgcatgcgct tctccttttc cattattata acagattttt ccatgctaga
    19381 tggtctgaaa ctgaatttga aatagcctgt ttttagccag tacaaacagg ctatgctact
    19441 agctaatttg agggaaattt gctaagataa ataaaaagaa aggagctctt atggccaata
    19501 tttttgacta tctgaaagat gtcgcatatg attcttatta cgaccttccc ttgaatgagt
    19561 tagacattct aaccttaata gaaatcacct acctctcctt tgataatctg gtctccacac
    19621 ttcctcaacg tcttttagat ctagcacctc aggttccaag agatcccacc atgcttacta
    19681 gcaaaaatcg ccttcaatta ttagatgaat tggctcaaca caagcgcttc aaaaattgca
    19741 aactctccca ttttatcaac gacatcgacc ctgaactgca aaagcaattt gcggctatga
    19801 cttatcgtgt cagcctcgat acctatctga ttgtctttcg tgggacagat gacagtatca
    19861 ttggctggaa ggaagatttc cacctgacct atatgaagga aattcctgct caaaagcacg
    19921 cccttcgcta tttaaagaac ttttttgccc atcatcctaa gcaaaaggtt attctagctg
    19981 ggcattccaa gggaggaaat ctcgctatct atgctgctag ccaaattgag caaagtttgc
    20041 aaaatcagat cacagcagtt tatacatttg atgcacctgg tctccatcaa gaattgacac
    20101 agactgcggg ttatcaaagg ataatggata gaagcaagat attcattcca caaggttcca
    20161 ttatcggtat gatgctggaa attcctgctc accaaatcat cgttcagagt actgccctgg
    20221 gtggcatcgc ccagcacgat acctttagtt ggcagattga ggacaagcac ttcgtccaac
    20281 tggataagac caacagtgat agccagcaag tagacacaac ctttaaagaa tgggtggcca
    20341 cagtccctga cgaagaactt cagctctact tcgacctctt ctttggcact attcttgatg
    20401 ctggtattag ctctatcaat gacttggctt ccttaaaggc gcttgaatac attcatcatc
    20461 tctttgtcca agctcaatcc ctcactccag aagaaagaga aaccttgggt cgccttaccc
    20521 agttattgat tgatactcgt taccaggcat ggaaaaatag ataatactct tgaaaattaa
    20581 atgtatacaa aacaaaagac ctagaataca tactttcatg tgcattctaa gtctttttaa
    20641 atagaatcta atagtcaata aaaatcaaag agcattgaga gataatgggg cttggaacgt
    20701 ccctctcgct tcaacaaaat gaccccatta tagattaaaa agatgccact tagaaaaagc
    20761 aaaaaaggaa gtaagacaaa ggtaaataca taaaaagcta actgaacatt ctcgtatcca
    20821 tttttataaa aaaggtagga tagataaaaa taacttgaaa tgagggataa taaaaataat
    20881 actggattcc acaaacttct attatccttc caaaatgaca ctataaaggc taatacaatt
    20941 tctataacga gatacatttc ttactccttt aatagctaca ttttatcata attatccaaa
    21001 gaaaaaaaga gggcatttat ccctcttaat ccttcatctg actctctgca tcggccacga
    21061 ctttttctag actggtctga ccaagttctg cctccatagt caactgaatt ctctccaatt
    21121 tttgatccaa aacatcatga atatgagctc ctacagggca atttggattc ggattgtcat
    21181 ggaaactgaa gagttgacct gtcttaccaa gacattcgac cgcctgataa acatctaaaa
    21241 gactaatatc cttaaggtcc ttgacaatct ctgttccgcc cgttccacgc gctactgaaa
    21301 tcagctctgc cttcttcaac tgggacaaga tctttctgat aatgacagga ttgaccccga
    21361 cactagcagc cagaaaatca ctggtcacct tgctttcctt cccctcgagg gcaatgatta
    21421 tcagcatatg agtcgcaatg gtaaatctac ttggaatttg catcctcttc tcctttttac
    21481 gaggctaccc tgcctctact cttctttttc tattattata ccctttttag ttgtaatgtc
    21541 aatcgttacc acttttcaac cagtcgtcta actcccgatc gcaaccctct ttctgagcca
    21601 attctctcaa aaattcctga tgatgagtat ggtggatccc attgaccaga ctttcatagt
    21661 aaacctcaaa atagggaagt ctcaggtctt tagccagctg caattcagct gccacatcgt
    21721 agtctacccg tcggaagtcc atatctacca ggcccttgcc atcaaactcc aaaatcatat
    21781 actgggcccg caagtccttc cgtagctgag cgtccaaaaa gaaaggttgg ccaatcgaac
    21841 ccggattgac aatcaattgc ccaccagtcc cgtgacgaag caactgctgg tgaatatgtc
    21901 cataaacagc aatatcacag ggaggatgag tcaccaagcg gtcaaaatcc tcttgtttgc
    21961 cagtatgaat caactctcgc ccccagttct tatcaggcag atgatggcta attcccactg
    22021 tcaaatcccc aaactgacga tgaatttgaa gaggttgatt gtggagcact tcaatttctt
    22081 ctagggaaat ttcctctaaa acatactggc actggcgcaa gagatagcgt tgactagggc
    22141 gagtactatc caattcctta cggacaccat gccaaagact gtcttcccag tttcccaaaa
    22201 ctctagccgt aatcggtagt tgatccaaca agtccaaaat ccttctacgt cctgtccctg
    22261 gcatgagaat atctcccaaa agccagtatt catccactcc tagctgctga gcatctgcca
    22321 aaacagcctc caaggcggtg gtatttccat gaatatctga aagaagagct attttcgtca
    22381 tatccatctc ctcgtttttt ctcttgcaat aagtataaca taaaaagtca cagctagaga
    22441 aatctagctt tttttgatat actagataaa gatattagac aagaggaaac gaatgacccc
    22501 aaacaaagaa gactatctaa aatgtattta tgaaattggc atagacctgc ataagattac
    22561 caacaaggaa attgcggctc gcatgcaagt ctctccccct gccgtaactg aaatgatcaa
    22621 acgaatgaaa agtgaaaatc tcatcctaaa ggacaaggaa tgtggctatc tactgactga
    22681 cctcggtctc aaactggtct ctgagctcta tcgtaagcac cgcttgattg aagtttttct
    22741 agttcatcat ttagactata caagtgacca gattcacgag gaagctgagg tcttggaaca
    22801 cactgtctct gacctgttcg tggaaagact agataaactg ctaggtttcc ctaaaacctg
    22861 cccccacgga ggaactattc ctgccaaggg agaactcctc gttgaaatca ataacctccc
    22921 actagctgat atcaaggaag ctggcgccta ccgcctgact cgggtgcacg atagttttga
    22981 cattctccat tatctggaca agcactcact tcacatcggt gaccagctcc aagtcaagca
    23041 gtttgatggc ttcagcaata ccttcactat cctcagtaac gacgaggatt tacaagtgaa
    23101 tatagacatt gcaaaacaac tctatgtcga gaaaatcaac taatttctca agtcccctac
    23161 caaccctgaa agttttattt tcagggtttt atttctatca tttgatttta ctttcatttg
    23221 gtggtagagt atttgaaaaa aagaaaggta gtttaaccta tgaaaaaatc actaaaaatt
    23281 tttgctacat ctaaatgatt tgacctcttc ggggttgctt tggtcgttgg gattgcgatt
    23341 gcatctggtt atctcaactc acgcctcgat aaatttgtag actggggact atggacagct
    23401 cttgtaccct ttggattgat ttccgtaacc aacgttggga tttccatgtt gtccactcgt
    23461 ttcacgggga aattaagcaa atggggaaat tactttggta ttgttaatac cattttgtcc
    23521 ggtgctattg attatatcct tggaaataag gcgaccatca ttacctatcc cgtcaccttc
    23581 ctcatttata cctttgctat aaagaaatgg aaagcttcgc aagaaggcag ccccaaccaa
    23641 atgagccaaa aacaggtaaa attggcggcc atcatcattt ccatcatcgc cttcctcttt
    23701 gcctttgtaa ccaactatat cggatatggg ggcaagatga atctccttgc ctacgtaaca
    23761 actattgcct ttgcactgtc cctcattgcc aatgctttga atgcattgaa actaacaact
    23821 cagtggggct tttggttgat ttacaatttc gttcagctga caaaagctgg tattcaagga
    23881 aacttcgcca atatcggtaa atacatcttt tatatcctca atgcaatcgg agctttattt
    23941 gtctggaatg atgaagaagt tagatacata gaaggaaact caaataaaga atactagcca
    24001 acttaagaga atctcccttc tgctattttt atcattttag ttgtaactcc cattcttttg
    24061 gagtagaatg aagttagata aaagaggaag gtcttgtcat gaaaaaactc tatagaatcc
    24121 attttatagc aattgcagtt attgatttgc tactatttgc attttttatc actagactcg
    24181 agacatcttt tgagtgcctc ttgctctctg gtttaatttt cttccttgct caaggactcc
    24241 tgctatttct cttggtcgtc cgactcaaac atcaattcgc tgagatttat cctcaaatca
    24301 ataaaaagat tcgcttctac tatttagggg ttctcaccat tgattttcta ttttttgttc
    24361 tcttagcctt cattagttct cagcgttttt catctcttat gccaattatc actgcttgcc
    24421 attctacttt ttattatatg acagctgact acctaggaga aaactatcca gacttttacg
    24481 acaaacacat ctctttatgg gagtgtctct aaggaaaagg aggttttagc atgaaaaaaa
    24541 atcatcttca tcaaaaccat tcaactcctt gtcattgatg gaatcatgct ggcatttttg
    24601 acatttaaaa aggggggctt acttgggact ggattttgat ttatagcggt tggctcattt
    24661 tctttcatcc tgtgctattg acctatcttt caaaccaact ttgtgaccac tttagtcaac
    24721 tctattccca gattagaccg agattctggc gttttgcttt acaaattctc ctatgggata
    24781 gcctgatgat tctctccttg gtgtctttaa gtgatattcc acttttcctt cagggaactc
    24841 tcctcatcct aggacatctc atcccttcct atcgcatctg ccaaagcctg aaaagagact
    24901 tcccccaagc atatcaagaa ccgatttctt tttggagtat tttatgatcg atgagaaaga
    24961 ccaagccgac tgggcttggt ctttcttatc tctttttagt atctaggata atggtaacag
    25021 gtccgttatt aaccagctca acctgcatat ctgctccaaa gatacctgtc tgaacgggca
    25081 cttcttgcgc taatttttga ttgaaagcat catagaagtc tgatgccata tcaggtttag
    25141 ctgcccctgt aaaggctgga cgattgcctt tcttagtatc cgcaaagagg gtaaactgag
    25201 aaatagagag gatttctcct tcaatatctt tgacagacag gttcatcttg ccttctacgt
    25261 ctgaaaaaat ccgcatattg accagttttc tcacagcata gtccaaatct tcctcttggt
    25321 cctctggtcc aacaccaacc agcaataaaa gtccctgatt gatttttccc tgaatctggc
    25381 cttctatact cacttgggct tttttaaccc gttggataat gattttcata atagccttcc
    25441 tagtaagagc taggacaact agccgttggt ccgtttgaca gagtaaactt ctggcacact
    25501 cttaatttta tcgacaaccg tggtcagtgt agagaggttg gcaataccga aggacacatg
    25561 gatattagca aacttcatat ccttggttgg ttgggcattg accgttgaaa tattcttggt
    25621 tgtatttgaa agaacttgca gtacatcgtt caacagtcct gtacggttga gaccgtagat
    25681 atcgatatgg gccatatact ccttatttga gctagagtac tggtcttccc attccacatc
    25741 aaggagacgt tgctcgtagt tttcttgggc acgcaggttc atacagtcca cacggtgaat
    25801 agccacacca cgacccttgg taatgtagcc aacaatatcg tcaccaggca cggggttaca
    25861 acacttagca atccgcacta ggagaccaga agcaccttca ataaccactc ccccctcatg
    25921 cttgaccttg agagtttctt tattttcaac cttgacctcg ccacctttga caagctcctc
    25981 tgcctcagcc ttggccttgg cacgctcttc ctcacggcgt tctttttcag tcagacggtt
    26041 aaagacggta atcgcaccga tttccccaaa accaatggcc gcaaagaggg agtcttctgt
    26101 cttgtaactg gtcttttgca gaacttgatc catgtggcgc ttgtccataa atttatttgc
    26161 cacatagcca ttttcttgga actgagccat cagcatctca cgacccttgt tgacagacaa
    26221 ttccttatct tggtttttaa agaactggcg aatcttattg cgcgccttgc tagtcttgac
    26281 catattgagc cagtcacggc taggtccaaa ggagttcggg ttggcgataa tttcaacctg
    26341 atcccctgtc tttaacttgg ttgtcagtgg aaccatgcgg ccattgacct tggcaccagt
    26401 tgctttttca ccgaccttgg tatggatttc gtaggcaaaa tcaatcggtc ctgaatcttt
    26461 gggaagagaa cggacagctc catctggggt aaaaacgtaa atctcctcag ccagatagtt
    26521 ttccttaaca gagtccacaa attccttagc atcatcagcc tggtcttgga gctctatcat
    26581 ctccttgatc cagttcattc caatagctga ttccttgctg ttaacttgcc cctttatacc
    26641 tttcttataa gcccagtgag ccgcaacccc gtactcagcc acctcgtgca tttccttggt
    26701 tcgaatctgg aattcaatcg gcccttttgg tccataaaca gtcgtatgga tagactgata
    26761 accattggcc ttgcggttgg cgatatagtc tttgaagcga cctggcatcg gtttccaaaa
    26821 ttcatgcacg taaccaagca tggcataaac atcactttgg gtatctaaaa tacaacgaat
    26881 agcaatcaga tcatagattt cctcaaaccg ttttctcttg tcctgcattt tgcggaaaat
    26941 tgagtaaata tgcttgggac gaccataaat cttccctttc aagtgacgtt ctgtcgtata
    27001 ctcctctaat tttgtgacta cctcatccac caaggcctca cgctccctgc gcttttcctt
    27061 catcatatgg gtaatcttgt aaaactccgt tggattgaga taacggaaag acaagtcttc
    27121 taattcccat ttgacactgg aaatccccaa acgatgggca agcggggcat agatttccat
    27181 ggtttctttg gaaatacgct cctgcttgtc ttttcgaaga tgtttcaggg tccgcatatt
    27241 gtgcaagcgg tcagacagtt tgaccaaaat aacgcggatg tcctcagaca tggccatgag
    27301 catcttgcga tgattttccg ctaattgctc ctcgatcgat ttgtactcga ccttgccaag
    27361 cttggtaact ccgtcaacaa tcatccgcac atcaggacca aactctcttt ccaaatcgtc
    27421 caaggtcgca tctgtatctt ccaccacatc atgcaagaat ccacaagcta ctgttacagc
    27481 atccagcttt agcttagcta aaatacctgc cacttggata gggtgaatga tataaggctc
    27541 gcctgatttg cgatattgac cactgtggca ttcaacagca tagaccaagg ccttatggac
    27601 aaaataaaca tcctcttccg ttaaatattc tttggttaaa gcgacaactt cttcgcctgt
    27661 taaattcact tctttcggca tctctactct ccaattcttc ctaccatttt atcacttttt
    27721 taagaatatg aaaactagat tggaacagaa taagaaaaaa ataattcaaa attgcttgat
    27781 aattctgaat tattggccca taatatacta cgaagttaga ttttaaactt aggtgataga
    27841 aggagagata gaagaacgga aaccatattg taacccaaag actttctgat ttccccaatt
    27901 ccattgaaga tacgaaagat aaacggtgga actcgtatca catacactgg taccttgact
    27961 ggattttgga attaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggt
    28021 tgctcaaagc actgctttga ggttgtagat aagactgaca aagtcagtca catatatacg
    28081 gcaaggcgac gttgacgcgg tttgaagaga tttttgaaga gtataaaaat cctcaagata
    28141 ctttcttcta tcctttagtt tataaggaga atacctatga aaaaaactgc tatttctatc
    28201 tttgctctcc taatgttagg agtttgctgc ctgttcctat tcagccagca aagctataaa
    28261 aaactcgttc aatactatgc taacgaccag aacctgccca gtaggataac ttatagtgaa
    28321 tatagcgaca aatgagaagc caactacggt agcactctaa acatcacgtc tatcaaacaa
    28381 gctaatgacg gagtttatgc aacctatgaa gggcaattga cacctttcca atattgataa
    28441 attgataacc agcctgtctt catctagtca tgctggtttt taagttcatt ttaaatcctt
    28501 acctattctc cctaactgtg ctatacttaa tttatactca atgaaaatca aagagcaaac
    28561 tagaaagcta gccgcaggct gttcaaagca ctgctttgag gttgcagata aagttgacgc
    28621 ggtttgaaga gattttcgaa gagtattagt acattctttg agattggagc tagtatgaaa
    28681 atccataaaa ccgtgaatcc tgttgcctat gaaaatacct attatctaga aggcgaaaag
    28741 cacctcatcg tcgtcgatcc tggtagtcat tgggaagcca ttcgtcagac aatcgagaag
    28801 atcaacaaac cgatctgtgc tattctcttg acccacgccc attatgacca tatcatgagt
    28861 ctggacttgg ttcgcgagac gtttggcaat cctcctgtct atatcgcaga gagcgaagcc
    28921 agctggctct acactcctgt cgataatctc tccggtctcc ctcgccacga tgatatggca
    28981 gatgtggtca caaaacctgc agaacacacc tttgtctttc acgaagaata ccaactagag
    29041 gaatttcgtt ttaaggttct accgacccca gggcactcta tcggtggtgt ttccctagtc
    29101 tttcctgatg ctcacctagt cttgacggga gatgctctat tccgcgaaac tatcggacgg
    29161 accgaccttc cgactggtag catggagcaa ctccttcata gtatccagac ccaactcttc
    29221 accctaccaa actacgatgt ctatccagga catggtccag ctactactat cgctcacgaa
    29281 aaggccttca atcccttttt ctagcaagat gatgacaatc gaaatttaag taaactatcc
    29341 agcaaatctt tctattacaa aaggcatcct atcaaggttt tcacacgtga ttggatgcct
    29401 tttttctgat gactagattt tttgtattac caaataatca cgcgctcctc tggtgaacgc
    29461 cacattccgt ctccttcttt gacatcatag gttgtaaaga aatcgtcgaa gtttggtact
    29521 tgcacattga cacggagttt ggctggtgcg tgcacatcga cgctagccaa aagtttcata
    29581 aattctggtc gacctttcat gcgccagatg cgaccgaagt tgtagaagaa ctcttctgct
    29641 gagaagtctg cttctctctt agctgcttca agcgctgctg cgattcctcc caagtcagcc
    29701 acgttttctg atacagtcaa tttaccgtta atggttgctc cataagaatc ctgtccatca
    29761 aattggtcaa tgactttttg tgttttctcc ttgaaggcag catagtcgct ctctgtccac
    29821 caatccttga ggctaccatt ttcgtcaaag gaagccccgt tagtatcaaa ggcgtgggaa
    29881 atttcatggg caatcactgc cccaatacca ccgtagttag cagaagatga ctgatgcaag
    29941 tcatagaaag gcgcctgtaa aatggccgct ggaaagacaa tcaggttctt ctgaggattg
    30001 tagtaggcat tgaccatatg agcaggcatg ccccattcct tataatctac aggctggttc
    30061 cacttactcc aactgtgctt gatttccaca cgcgcaaagg ctagagcatt ctcaaaaaga
    30121 ctggcagttt cattcactac cttatccttg taacgtgcag gcaattcttc tggatagcca
    30181 atataaggtt tgatcacatt gagcttcacg atagcctgtt tacaggtttc tggagtgagc
    30241 cagtcattct taagcagacg ctccttataa acatcaatca tggttgccac ttttttctcc
    30301 acatccgcct tggcttctgg agagaacttc tcacgggcgt accaaagacc cagggcttgc
    30361 ttgaaaggtt cttgtgctag atgataagct gctttgacct tatcttttgc ctctggaact
    30421 ccagaaaggg cacggctgta ggcaccagac aaaacacgga tatcctctgt taaatagctg
    30481 gttgaaagat tgacaacact caaaatcaag gttgctttaa ggagagacca ggcttcctca
    30541 ctgtagaatt gctctgctgc ttgccagaaa cgttcctcgt ctacaataac cttgtctggt
    30601 aattgcccaa taactgcttt gaagaagtca tccaaaggta gggcaggcgc gaatttcttg
    30661 aaatcttcgt aagaatatgg atgatagagt ttagcatatt ctgaactttc ttcattagag
    30721 agcaccactg tcgcaactcg gcggtccaat tcaagtcttt tttctagcaa gtcttcaatt
    30781 tcttcatcag agaaatcata agccttgagg agatttgcgc tgctttcttt ccaaagagtc
    30841 aagagctctt cgcgctgagg atgttcttct gcatagtagg tcgtatctgg caagattgtg
    30901 cttggagcgc tagcccatag aacattgatt ctagcatcca taaagtctgg cgatacacca
    30961 aaaggaagga agtttggttt tcctgcaagc tcaaactctg ctagtttagc tgtaaaatcc
    31021 gcaaaagtct ccaattcttg gaattcttta aggagtggta agacaggtgt gataccgtca
    31081 gcttctctct tgtcaaaatc acgaactagg cggtggtatt tgacaaagtt ttccaagata
    31141 gcatcctcag gcacttcttc acctgctaac cacttgtctg ttgtcgccag catcaggtct
    31201 tcaatttcct ggtctaaatc aacaaaacct cctgtttgag acttatctgc tgggatttca
    31261 gctgtctgtt gccattctcc attgatagca tcataaaaat catcttgata acgtgtcatc
    31321 ttgttctcgc tttcatttgt atttgcattt atcttaacaa aaatcactag ggaatgcaat
    31381 taataaccat ttaactatta ttttttagct attataaaaa atctttccat gataaaa
//
LOCUS       DAVKMO010000021        28582 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVKMO010000021 DAVKMO010000000
VERSION     DAVKMO010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28582
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.021"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(56..1066)
                     /locus_tag="VW361_001093"
     CDS             complement(56..1066)
                     /locus_tag="VW361_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU9744145.1"
                     /translation="MSFLSKNGAGILVCLLISILSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VW361_001094"
     CDS             1215..2384
                     /locus_tag="VW361_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9744146.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VW361_001095"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VW361_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU9744147.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDERRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VW361_001096"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VW361_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU9744148.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRVKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETEVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VW361_001097"
     CDS             4146..4379
                     /locus_tag="VW361_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9744149.1"
                     /translation="MKEKEIFDSIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
     gene            4425..4716
                     /locus_tag="VW361_001098"
                     /pseudo
     CDS             4425..4716
                     /locus_tag="VW361_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4919..5149
                     /gene="blpU"
                     /locus_tag="VW361_001099"
                     /pseudo
     CDS             4919..5149
                     /gene="blpU"
                     /locus_tag="VW361_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
     gene            5864..8017
                     /locus_tag="VW361_001100"
     CDS             5864..8017
                     /locus_tag="VW361_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU9744150.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELVEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8030..9379
                     /locus_tag="VW361_001101"
     CDS             8030..9379
                     /locus_tag="VW361_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU9744151.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9549..10256
                     /locus_tag="VW361_001102"
     CDS             9549..10256
                     /locus_tag="VW361_001102"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU9744152.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10458..14183
                     /locus_tag="VW361_001103"
     CDS             10458..14183
                     /locus_tag="VW361_001103"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU9744153.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKNIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISEIRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14276..15718
                     /locus_tag="VW361_001104"
     CDS             14276..15718
                     /locus_tag="VW361_001104"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU9744154.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDSLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15755..16777
                     /locus_tag="VW361_001105"
     CDS             15755..16777
                     /locus_tag="VW361_001105"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU9744155.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGAIGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16774..17319
                     /gene="purN"
                     /locus_tag="VW361_001106"
     CDS             16774..17319
                     /gene="purN"
                     /locus_tag="VW361_001106"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU9744156.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            17403..17912
                     /locus_tag="VW361_001107"
     CDS             17403..17912
                     /locus_tag="VW361_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9744157.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17937..19484
                     /gene="purH"
                     /locus_tag="VW361_001108"
     CDS             17937..19484
                     /gene="purH"
                     /locus_tag="VW361_001108"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU9744158.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAANKYGLTMVFT
                     GVRHFRH"
     gene            19606..20868
                     /gene="purD"
                     /locus_tag="VW361_001109"
     CDS             19606..20868
                     /gene="purD"
                     /locus_tag="VW361_001109"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU9744159.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRTAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTVATVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKASK"
     gene            21271..21759
                     /gene="purE"
                     /locus_tag="VW361_001110"
     CDS             21271..21759
                     /gene="purE"
                     /locus_tag="VW361_001110"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU9744160.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRILSVEDKSIADALANFAEEQGKITEESSNE
                     LI"
     gene            21746..22846
                     /gene="purK"
                     /locus_tag="VW361_001111"
     CDS             21746..22846
                     /gene="purK"
                     /locus_tag="VW361_001111"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU9744161.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEVD
                     LEAAYALADSADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTI
                     VPARISESLVDKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSI
                     EACDFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYG
                     KIEAKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            22856..23083
                     /locus_tag="VW361_001112"
     CDS             22856..23083
                     /locus_tag="VW361_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU9744162.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            23146..24444
                     /gene="purB"
                     /locus_tag="VW361_001113"
     CDS             23146..24444
                     /gene="purB"
                     /locus_tag="VW361_001113"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU9744163.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24499..28425)
                     /gene="strH"
                     /locus_tag="VW361_001114"
     CDS             complement(24499..28425)
                     /gene="strH"
                     /locus_tag="VW361_001114"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9744164.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPATEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKKIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDIL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQEEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEILSQPAPAEESK
                     ALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
BASE COUNT         7925 a         5618 c         6919 g         8120 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaga
       61 aaatgccgat aagggtctgc ataccaaggc tggtgaggat gatggcaatc cagcagacgg
      121 ctccgagaac aatggatttt ccactggatt tgaccatagc gaccagatta gttttgagac
      181 cgatggcact catggccatg ataatgagga atttagagag ttgtttgaga ggggtaaaga
      241 aactactaga cacaccgaga gaggtcagaa gggtggttag gagcgatgca aggatgaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaagcc ttgcttattt ttttgctcgc
      361 gactttgcca gtaggagaga aagagagtga tggggatgat agctagggtg cgcgtgagtt
      421 tgacaatggt tgcggattcg agggtattgg tctggtagag actgtcccaa gcgctagctg
      481 tggcggttac agaggaagta tcattgaccg cagttcctgc aaagagggcg aagccgtcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggagatggct tgggctactt ccttttcctt agcatggata acaggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaatcaag gtagccagtt
      721 ttgtatccag ggcaaagaag cgctggaaga ggtaggcaac aatcaaggct attgaaatgg
      781 tggaaaggat gacagggagt gaagattgcc caactgcgaa gacttgagag atattgagac
      841 caaaaccaag taagataacg gcatactgga gcaatttctt ggaactaaag gtcaatccaa
      901 catccagttg tttataagac gagagaaagg gatgtaggag catgcccata aaaatcgcaa
      961 aaacgggtgc gccaataaca gggaagaatc ctcctaagta ccaagatagg atggaaatga
     1021 gaaggcagac caagatgcct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 agaatctgtt accattatag acctgtaaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcgggaggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggcta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcgg
     1441 ccagtgattt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaatcttgg
     1501 tcactatcgg agcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtgct cttgccagct cctgcttatc cgggttatga accgatcgtc aatctagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacgggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat ttttgctcct gcgaccttca
     1981 cagcccagtt aatcaagagt caccagtact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaacgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgtctct gtccagagca ttatcatgag gatgagagac gttgccatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaactata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat cgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactctacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attcggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgctttgt tggctgctgg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggacttatgt caacattgcc gactgtagat
     3541 gggaaaggtt ttgacatgct tgacctcggt gctaatgcag aaaatacagc ccagcacctc
     3601 catcaatacg ctgtcctagg ttctttctat gccaagaatg ttcgtggcat tgcgcaacca
     3661 cgtgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagtgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt caaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgccagatt
     4081 cgtaccatgc tagaaacaga agtagttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgaa agaaaaagaa atttttgaca gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgacttggat gctgactcag
     4261 ttgatttgat ggagtttatc ttgacgctgg aggatgaatt tagtatcgaa atcagcgatg
     4321 aggaaattga ccaactccaa agtgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaacttccac gtaaatccag caaactcaag ccgctaacag ttgaagataa agcctgtaat
     4561 catgcgctat ctaaggagag aagcaaggtt gagaatatct ttgccaaagt aaaaacgttt
     4621 aaaatgtttt caacaaccta tcgaaatcat cgtaaacgct tcggattacg aatgaatttg
     4681 attgctggta ttatcaatca tgaactagga ttctagtttt gcaggaagtc taatagtaaa
     4741 aaagtgatta gaaaacatct tttttaaaaa tagagatgat tttgaaacaa aaaagctaat
     4801 tcaagacgtt tcgatgccaa ttcaagattt ggatgaaaag aattaataga tactgttata
     4861 ctaaacttgt caagtttgta acaagacaaa tattaaaaat aaaaaagagg tattcgttat
     4921 gaatacaaaa aagatgtcac aatttgaaat tatggatact gagatgcttg cttgagttga
     4981 aggtggcgga tgcaattggg gagattttgc caaagcaggt gttggaggag gagtagcacg
     5041 aggtcttcag ctaggaatta aaacaagaac atggcaaggt gcagcaactg gtgctgcggg
     5101 aggagctata cttggaggtg tggcctatga agcgacatgt tggtggtaat tatggatttt
     5161 aaaagtttta ttattggttt agtagttggt atatttggtc cttatatgga tgatttaatt
     5221 agaaaaaaat ttttaaagtc ttcggagaag aaaacagaaa aatctgttaa aaaataatca
     5281 aaactataaa tgatgaatct gaatcaaaat tattttgcgc atgtaaagag gagtcttata
     5341 gtaacgagtc aaaaaaggag taactatgaa tcgtaattta gaacggtgtt atctattctg
     5401 actagggata gatcatacca taggtagctt agaaatagca gagacattag aaattgaagt
     5461 aataaatagg atgtcgtaag tgttactatc aatgatttat ttgtttcaag cttgcctagg
     5521 gtgtcagtaa aaaatcattt tcctttcaat agcatatttt tagtgggcag gactcttgtt
     5581 ctgcctattt ttttatccaa aaagtgcagt tgggagggag ataggctcat ttgggaagga
     5641 agtccagttt ttgtttagtg attggggtaa gatagttgtt atcagatgag tttatactct
     5701 tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tatatatgtg actgacttcg
     5761 tcagtcctat ctacaacctc aaaacagtgt tttgagcagc ctgcggctag tttcctagtt
     5821 tgctctttga ttttcattga gtattaggga aaaggagatg aatatgaaat ttgggaaacg
     5881 tcactatcgt ccgcaagtgg atcagatgga ctgcggtgta gcttcattag ccatggtttt
     5941 tggctactat ggtagttatt attttttggc tcacttgcga gaattggcta agacgaccat
     6001 ggatgggacg acggctttgg gcttggtcaa ggtggcagag gagattggtt ttgagacgcg
     6061 agccattaag gcggatatga cgctttttga cttgccggat ttgacttttc cttttgttgc
     6121 ccatgtgctt aaggaaggga aattgctcca ctactatgtg gtgactgggc aggataagga
     6181 tagcattcat attgccgatc cagatcccgg ggtgaagttg actaaactgc cacgtgagcg
     6241 ttttgaggaa gaatggacag gagtgactct ttttatggca cctagtccag actataagcc
     6301 ttataaggaa caaaaaaatg gtctgctctc ttttatccct atattagtga agcagcgtgg
     6361 cttgattgcc aatatcgttt tggcaacact cttggtaacc gtgattaaca ttgtgggttc
     6421 ttattatctg cagtctatca ttgataccta tgtgccagat cagatgcgtt cgacactagg
     6481 gattatttct attgggctag tcatcgtcta catcctccag caaatcttgt cttacgctca
     6541 ggagtatctc ttgcttgttt tggggcaacg cttgtcgatt gacgtgattt tgtcctatat
     6601 caagcatgtt tttcacctcc ctatgtcctt tttcgcgaca cgcaggacag gggaaattgt
     6661 gtctcgtttc acggatgcta acagtattat cgatgcgctg gcttcgacca ttctttcgat
     6721 tttcctagat gtgtcaacag ttgtcattat ttcccttgtt ttattttcac aaaataccaa
     6781 tctctttttc atgactttat tggcgcttcc tatctacaca gtgattatct ttgcctttat
     6841 gaagccgttt gaaaagatga atcgggacac catggaagcc aatgcggttc tgtcttcttc
     6901 tatcattgag gacatcaacg gtattgagac tatcaagtcc ttgaccagtg aaagtcagcg
     6961 ttaccaaaaa attgacaagg aatttgtgga ttatctgaag aaatccttta cctatagtcg
     7021 agcagagagt cagcaaaagg ctctgaaaaa ggttgcccat ctcttactta atgtcggcat
     7081 tctctggatg ggggctgttc tggtcatgga tggcaagatg agtttggggc agttgattac
     7141 ctataatacc ttgctggttt actttaccaa tcctttggaa aatatcatca atctgcaaac
     7201 caagcttcag acagcgcagg ttgccaataa ccgtctaaat gaagtgtatc tagtagcttc
     7261 tgagtttgag gagaagaaaa cagttgagga tttgagcttg atgaagggag agatgacttt
     7321 caagcaggtt cattacaagt atggctatgg tcgagacgtc ttgtcggata tcaatttaac
     7381 cgttccccaa gggtctaagg tggcttttgt ggggatttca gggtcaggta agacgacttt
     7441 ggccaagatg atggttaatt tttacgaccc aagtcaaggg gagattagtc tgggtggtgt
     7501 caatctcaat cagattgata aaaaagccct acgccagtac atcaactatc tgcctcaaca
     7561 gccctatgtc tttaacggaa cgattttgga gaatcttctt ttgggagcca aggaggggac
     7621 gacacaggaa gatatcttac gggcggtcga attggtagag attcgagagg atatcgagcg
     7681 catgccactg aattaccaga cagaattgac ttcggatggg gcagggattt caggtggtca
     7741 acgtcagaga atcgctttgg cgcgtgctct cttgacagat gcgccggtct tgattttgga
     7801 tgaggcgact agcagtttgg atattttgac agagaagcgg attgtcgata atctcatggc
     7861 tttggacaag accttgattt tcattgctca ccgcttgact attgctgagc ggacagagaa
     7921 ggtggttgtc ttggatcagg gcaagattgt cgaagaagga aagcatgctg atttgcttgc
     7981 acagggtggc ttttacgccc atttggtcaa tagctagaaa gaggagagga tgaaaccaga
     8041 atttttagaa agtgcggagt tttataatcg tcgttaccat aatttttcca gtagtgtgat
     8101 tgtacccatg gcccttctgc tcgtgttttt acttggcttt gcaactgttg cagaaaagga
     8161 gatgagtttg tccactagag ctactgtcga acctagtcgt atccttgcaa atatccagtc
     8221 aactagcaac aatcgtattc ttgtcaatca tttggaagaa aataagctgg ttaagaaggg
     8281 ggatcttttg gttcaatacc aagaaggggc agagggtgtc caagcggagt cctatgccag
     8341 tcagttggac atgctaaagg atcaaaaaaa gcaattggag tatctgcaaa agagcctgca
     8401 agaaggggag aaccactttc cagaggagga taagtttggc taccaagcca cctttcgcga
     8461 ctacatcagt caagcaggca gtcttagggc tagtacatcg caacaaaatg agaccatcgc
     8521 gtcccagaat gcagcagcta gccaaaccca agccgaaatc ggcaacctca tcagtcaaac
     8581 agaggctaaa attcgcgatt accagacagc taagtcagct atggaaacag gtgcttcctt
     8641 ggccagtcag aatctagcct actctcttta ccagtcctac aagtctcagg gcgaggaaaa
     8701 tccccaaact aaggttcagg cagttgcaca ggttgaagca cagatttctc agttagaatc
     8761 tagtcttgct acttaccgtg tccagtatgc aggttcaggt acccagcaag cctatgcgtc
     8821 agggttaagc agtcaattgg aatcccttaa atcccaacat ttggcaaagg ttggtcagga
     8881 attgaccctt ctagcccaga aaatcttgga ggcagagtca ggtaagaagg tacagggaaa
     8941 tcttttagac aaggggaaaa ttacggcgag tgaggatggg gtgcttcatc ttaatcctga
     9001 gaccagtgat tctagcatgg ttgcagaagg tgccctacta gcccaacttt atccatcttt
     9061 ggaaagagaa gggaaagcca aactcacagc ctatctaagt tcaaaagatg tagcaagaat
     9121 caaggtcggt gattctgttc gctatactac gactcatgat gccgggaatc aacttttcct
     9181 agattcaact attacaagta ttgatgcgac agctactaag actgagaaag ggaatttctt
     9241 taaaatcgag gcggagacta atctaacttc ggagcaggct gaaaaactta ggtacggggt
     9301 ggaaggccgc ttgcagatga ttacgggcaa gaaaagttat ctacgttatt atttggatca
     9361 atttttgaac aaagagtaat gttcgtgttt ttagagttaa ataattttta aactgtgaga
     9421 aagattcttc ttgcagtttt ttctttacaa tttttgaaaa acatctacta tttattcggt
     9481 taaattcttg tgttttttgg ttttttgtgg taaaatgtgc tcaagtaata cgaaaggcga
     9541 actttaaaat gtcaaaacaa ttgatctatt cgggaaaagc taaagatatc tatacaactg
     9601 aggatgaaaa tcttattatt tcaacttaca aggaccaggc gactgctttc aacggtgtca
     9661 agaaggagca gattgcaggt aagggagtct tgaataatca gatctcatct tttatttttg
     9721 agaaattaaa tgcggctggt gtggcgactc actttgtgga gaaactttca gacacggaac
     9781 aactcaataa aaaggttaag attattcctt tggaagtcgt gctccgcaac tatactgctg
     9841 gttccttttc aaaacgtttt ggtgtggatg agggaatcgc cttggagact ccgattgtcg
     9901 aattttacta caaaaatgat gatttggatg atccatttat caatgatgag catgtgaaat
     9961 tcctacagat tgcgggtgac cagcagattg cctacttgaa ggaagaaacg cgtcgtatca
    10021 atgaactatt gaaagtctgg tttgctgaga ttgggcttaa attgattgac tttaagctag
    10081 agttcggttt tgacaaggat ggcaagatta tcttggcaga cgaattttca ccagataact
    10141 gccgcttgtg ggacgctgat ggcaaccaca tggataagga tgttttccgt agaggattgg
    10201 gagaactaac cgacgtttat gagattgttt gggaaaagtt gcaggaattg aaataatctg
    10261 tttgcaacgg aaaaccttcg tctctcaact aaaaggactc aggctgaaaa ggtcccccag
    10321 accttttcac tctgtagaga actaggtgaa ctaacagatg tttacgaaat tgtctgggaa
    10381 aagttgcagg gtttaaaata acaacctcaa ggctgtttgg gaatattgca agagctgaaa
    10441 taaaggaata agaattgatg gataaacgta tttttgttga aaaaaaggct gattttcagg
    10501 tcaagtcaga gagtttggtt agagagctcc agcacaactt gggactgtca agcttgaaaa
    10561 gtattcgtat tgtgcaagta tatgatgtat ttgacttggc tgaggacttg tttgcacctg
    10621 cagagaagca cattttctct gagcagggaa ccgaccatgt tttagatgaa gtatctgtgc
    10681 aggcggatct tgctaactat gctttctttg ccattgaaag tctgccaggg cagtttgacc
    10741 agcgtgcagc ttcgtcacag gaagccttgc ttttgttggg aagttcgagt gacgtgacag
    10801 tcaacacagc ccaactttac ttggtgaata aagatattga tgcgactgag ttggaagctg
    10861 tcaaaaacta cctgctcaat ccagttgatt ctcgtttcaa ggatatcacg acagggattg
    10921 ccaagcagga gttttcagag tcagacaaga ccattccaaa attgactttc tttgaaagct
    10981 atacagcaga agactttgct cgctacaagg ccgagcaagg gatggccatg gaagtggatg
    11041 atttgctctt tatccaagac tactttaagt caatcgggcg cgtgccaact gagactgaac
    11101 tcaaggtttt ggacacttac tggtctgacc actgccgtca tacgactttt gagacagagt
    11161 tgaaaaacat cgacttttca gcttctaaat ttcaaaagca attgcagtca acctatgaca
    11221 agtatattgc catgcgcgag gaattaggtc ggtctgaaaa accacaaacc ttgatggata
    11281 tggcgactat tttcggtcgt tatgagcgtg ctaatggacg attggatgat atggaagtct
    11341 ctgacgaaat caatgcctgc tcagttgaaa ttgaagtgga cgttgatggt gtcaaggaac
    11401 cttggctcct catgtttaaa aatgaaaccc acaaccatcc aacagaaatt gagccatttg
    11461 gtggagcggc tacctgtatc ggtggagcta ttcgtgatcc gttgtcaggc cgttcctatg
    11521 tttaccaagc catgcgtatt tcaggtgctg gtgatattac agcaccgatt tcggaaattc
    11581 gtgctgggaa attgccacaa caagtcattt ctaaaacagc agctcatggt tattcttcat
    11641 atggtaacca gattgggctt gccacaacct acgttcgtga atacttccac ccaggctttg
    11701 tagctaaacg tatggaactt ggtgccgttg ttggtgcggc tcccaagggc aatgttgtcc
    11761 gtgaaaaacc tgaagcaggt gatgtgatca tccttctcgg aggcaaaaca ggtcgtgatg
    11821 gtgtcggtgg tgcgacgggc tcttctaagg ttcaaacagt tgagtctgta gagactgctg
    11881 gtgctgaggt tcaaaaagga aatgccatcg aagaacgcaa gattcagcgc ctcttccgta
    11941 atggcaatgt cactcgtctg atcaagaagt ccaatgactt tggggcaggc ggcgtctgtg
    12001 tggctattgg tgaattggca gacggtcttg aaatcgacct caacaaggtg cctcttaaat
    12061 accagggctt gaatggtaca gaaattgcca tctctgaatc acaagaacgg atggcggtcg
    12121 tggttcgtcc tgaagatgtg gatgccttcg ttgccgaatg taacaaagaa aatattgatg
    12181 ctgttgtggt ggcgacagta actgaaaaac caaatcttgt catgcactgg aatggtgaga
    12241 caatcgttga cttggagcgt cgtttccttg acaccaatgg tgtgcgcgtg gttgtcgatg
    12301 ccaaagttgt ggacaaggat gtcaaactcc cagaagagcg tcaaacatct gctgaaacac
    12361 tggaatcaga tacccttacg gttctatctg acctcaacca tgcaagtcaa aaaggattac
    12421 agactgtctt tgactgctct gttggacgct caacggttaa tcacccactt ggtggtcgtt
    12481 accaactcac accaactgag gcatctgtgc agaaattgcc agttcaacac ggtgtgactc
    12541 atactgcgtc ggtcattgct caaggtttca acccatatgt agctgaatgg tctccatacc
    12601 acggtgctgc ttacgcggtt atcgaagcaa ctgctcgttt ggtggctgct ggtgccaact
    12661 ggtctaaggc tcgtttctct taccaagaat atttcgagcg gatggacaag caagcagagc
    12721 gttttggtca gccagtagcc gcccttctag gctctattga agctcagatt caacttggct
    12781 tgccatctat cggtggtaag gactccatgt ctggtacctt tgaagaattg accgttccgc
    12841 caaccttggt tgcctttggg gtgacgacgg cagatagccg taaggtgctc tctccagaat
    12901 ttaaagctgt tggggaaaat atctactaca tcccaggtca agccctctct gcagagattg
    12961 attttgactt gattaagaaa aattttgctc agtttgaagc aagccaagct gaccataaag
    13021 tgacatctgc atcagctgtc aaatacggtg gtgtagttga aagtttggct cttgctacct
    13081 ttggaaacta tattggtgca gaggtgacct tgcctgaact taaaacagct ttgacagctc
    13141 aattaggcgg ctttgtcttc acatctcctg aagaaattgc tggagtagag aagattggac
    13201 aaacgaaagc agactttaca ctgactgtca acggtgtgaa gctagatgga cacaagcttg
    13261 acagtgcatt tcaagggaca ttggaagaag tttacccaac agaatttacc caagcgaaag
    13321 aactagaaga agtaccagct gtggcatcag atgttgtgat taaagccaaa gaaaaggttg
    13381 aaaaacctgt ggtttacatc ccagtctttc caggaaccaa ctcagaatat gattcagcta
    13441 aggccttcga aaaagaaggt gcagaggtca atttggtgcc attcgtgacc ttgaatgaag
    13501 aagctattgt caagtcagtt gaaactatgg ttgacaatat cgacaagact aatattctct
    13561 tctttgccgg tggattctcg gctgcggatg aaccagatgg ttcagctaag tttatcgtca
    13621 atatcctgct taatgaaaaa gtgcgtgtgg ctattgatag ctttatcgcc cgtggtggct
    13681 tgattatcgg tatttgtaat ggattccaag ccttagtcaa atcgggtctc ctaccatacg
    13741 gaaactttga agatgctaac agtactagtc caaccctctt ctacaatgat gccaaccaac
    13801 acgtggccaa gatggtggaa actcgcattg ccaataccaa ctcaccatgg ttggctggtg
    13861 tgcaagtggg cgatatccac gctattcctg tttcgcacgg tgaagggaag tttgtcgtga
    13921 cggctgagga atttgcagag ctccgtgaca atggacaaat tttcagccaa tacgttgact
    13981 ttaacggtaa accaagtatg gattctaagt acaatccgaa tggttctgtc catgccatcg
    14041 aaggaattac cagcaagaat ggtcaaatca tcggtaagat gggccactca gaacgttatg
    14101 aggatggtct tttccaaaat atcccaggca ataaagacca acacctgttc gcatcagcgg
    14161 ttaaacattt cactggaaaa taagacttac agattttcta atagatagta tcagtaatgt
    14221 aaaagtcatg taaatctagc tcttgatgat tacaaatgaa aattaggtat aaaaaatgac
    14281 atacgaagta aaatctctta atgaagaatg tggtgttttc ggtatttggg gacatccaga
    14341 tgctgctaag ttgacctatt ttggactcca cagtcttcaa caccgtggtc aggagggggc
    14401 aggaatcctc tccaacgatc aaggacaact gaagcgccat cgtgacatgg ggcttttatc
    14461 agaagttttc agaaatccag ctaatttgga taaattgaca ggagctggtg cgattgggca
    14521 tgtgcgttat gcgactgctg gcgaagcttc tgtagataac atccagccct tcctcttccg
    14581 ttttcacgat atgcagtttg gcttggctca taatggaaat ctgaccaatg cagcctctct
    14641 caagaaagaa ctggaacaaa gaggagcaat tttcagcgcg acttcggact ctgaaatctt
    14701 ggctcacctc attcgtcgca gtcataatcc tagcctgatg ggcaaaatca aggaagcgct
    14761 cagccttgtc aaaggtggtt ttgcctatat cttgctgttt gaggacaagt tgattgcggc
    14821 tcttgaccct aatggctttc gtccgctttc tatcgggaaa atggccaacg gagcggtggt
    14881 tgtttcctct gaaacctgtg cttttgaggt cattggtgcc gagtggattc gtgatttgaa
    14941 gccaggtgag attgtgatca ttgatgacga gggcattcag tatgacagct atacagatga
    15001 tacccagttg gcgatttgtt ctatggagta tatctacttt gcccgccctg attctaatat
    15061 ccacggtgtc aatgtccata cggcacgtaa gagaatggga gcgcaattgg cgcgagaatt
    15121 taagcatgag gcagatattg tagttggtgt gcccaattct tccctaagcg cggctatggg
    15181 atttgcggaa gaatcaggct taccaaatga aatgggtctg atcaaaaacc aatacaccca
    15241 gcgaactttt atccaaccga ctcaagaatt gcgggagcaa ggagtgcgga tgaaactgtc
    15301 tgctgtttcg ggtgttgtca aaggcaaacg tgtggtcatg gtggatgatt ccattgtacg
    15361 tggaacaacc tctcgtcgta tcgttcagct cttgaaagaa gcgggtgcga ctgaggttca
    15421 cgttgccatt ggaagtcctg cactagcgta tccatgtttc tacgggattg atatccagac
    15481 ccgtcaggag ctgattgcag ccaatcatac ggtcgaagaa actcgccaaa tcattggtgc
    15541 ggacagtctg acttatcttt caattgatag cttgattgag tcgattggta tcgaaacaga
    15601 tgcgccgaac ggtggtctct gtgtcgctta ctttgacggt gactacccaa cgcctctcta
    15661 tgactacgaa gaagactatc gtagaagttt ggaagaaaag accagttttt acaagtaggc
    15721 gacagattct ccattaaaga aaaggaaaaa acaaatgaca aataaaaatg catatgccca
    15781 gtcgggtgtg gatgttgaag cgggttatga agttgttgaa cggattaaaa agcacgtggc
    15841 ccgtacggag cgtgcaggtg tcatgggagc tattggtggc tttggtggta tgtttgacct
    15901 ttccaagact ggggttaaag aacccgtctt gatttcaggg actgacggtg tcggaaccaa
    15961 gctcatgttg gctatcaagt acgacaagca cgataccatc gggcaggact gtgtggccat
    16021 gtgtgtcaac gacatcattg ctgcaggtgc ggaacccctc tattttctcg actacgtagc
    16081 gacagggaag aatgaaccag ctaagctaga acaagtggtt gctggtgtgg cagaaggttg
    16141 tgtgcaggct ggtgctgccc tcatcggtgg ggaaacggct gaaatgccgg gcatgtacgg
    16201 cgaagacgac tatgacttgg ctggttttgc ggtcggtgtg gctgaaaaat ctcaaatcat
    16261 tgacggttca aaggtggtag agggagatgt tcttctcgga cttgcttcaa gtgggattca
    16321 ctcaaatggt tactctttgg ttcgtcgtgt ctttgcggat tacacaggtg aggaagtcct
    16381 accagaattg gaaggcaaga aacttaagga agttctactt gagccgactc gtatctatgt
    16441 caaggctgtc ttgccgctca tcaaagaaga gttggtcaac ggcattgccc acatcacagg
    16501 tggtggcttt atcgaaaatg tccctcgtat gtttgcagat gacctagctg ctgaaattga
    16561 tgaaagcaaa gttccagtac ttccaatttt caaagccctt gaaaaatatg gtcagattaa
    16621 acacgaagaa atgtttgaaa tcttcaatat gggtgtggga cttatgttgg cggtcagccc
    16681 tgaaaatgta gagcgtgtaa aagaattgtt ggatgaagca gtctatgaaa ttggtcgcat
    16741 cgtcaagaaa gaaaacgaaa gtgtcattat caaatgaaaa aaatagcggt ttttgcctct
    16801 ggtaatggct caaattttca ggtgattgcc gaagaatttc cagtggagtt tgtcttttca
    16861 gaccatcgtg atgcctatgt gcttgagcgt gcaaagcagc tcggcgttct gtcctatgct
    16921 tttgaactca aggagtttga gagcaagaca gactacgaag cagcccttgt cgaactcttg
    16981 gaagaacacc agattgactt ggtttgccta gcaggctaca tgaaaatcgt tggaccaacc
    17041 ttattgtcgg cttatgaagg tcggattgtc aacattcatc cagcctactt gccagaattt
    17101 ccaggagctc atgggattga ggatgcttgg aatgctggcg tgggtcagtc tggtgtgacc
    17161 attcactggg tggattcggg tgtggataca ggccaggtca tcaaacaggt tcgtgtgcca
    17221 cgactagctg atgataccat tgacagattt gaagctcgca tccatgaagc agagtacagg
    17281 ttgtatccgg aagtagtgaa ggctctattt acagattgac tttttgatga ttcatatgat
    17341 atctttgatt ttaaattgga gtcagtgttt gttgaagacg gcttcaaacg gaggtatttg
    17401 taatgttaga atctaaaaaa acaactcgat atgtatttta tgtctatctg atgttattaa
    17461 cttggggaat cttatttaag tttgaaacaa atcctgaatt tatagcattt ttcttagctc
    17521 caaggtatat caattggatt ccattttcag aaccactaat agtcgatgga aaaattgttt
    17581 ttgctgaaat gttatttaat ctgatttcct ttattccatt aggtgtttgt ttccctttga
    17641 taaaaactaa tttatctagt ttaagaatag tcgggacagg tttcttgatt agtttattgt
    17701 ttgagtgctt acagtatatt ttagcaatag gtataacaga tataacggat ttgactttaa
    17761 atacgctagg tgtctgtgta ggcttactga tttatcaaat ttttataaga gtgttcaaat
    17821 cacagactag aaaatggatc aatatcttag gtatgcttag ccttggtttt gcttatcttg
    17881 ttttactgtt actgcattta attggtgttt aactaatgat taaaaaggag aatataatga
    17941 ctaaacgcgt cttaatcagc gtctcagaca aagcgggcat tgttgaattt gcccaagaac
    18001 tcaaaaaact tggttgggag attatctcaa caggtggaac taaggttgcc cttgataatg
    18061 ctggggtgga taccattgct atcgatgatg tgactggttt cccagaaatg atggacggtc
    18121 gtgtgaagac cctccaccca aatatccacg gagggcttct cgctcgtcgt gacttggata
    18181 gccacttgga agcggctaag gacaacaaga ttgagctcat tgaccttgtg gtggtcaacc
    18241 tttacccatt taaggaaact atccttaaac cagatgtgac ttatgctgat gcagttgaaa
    18301 atatcgatat tggtgggccg tctatgcttc gttcagcagc gaaaaatcat gccagtgtta
    18361 cagttgtggt agatcctgct gactacgctg tggttttgga cgaattggca gcaaacggcg
    18421 aaacctctta tgaaactcgc caacgtttag cagccaaagt atttcgtcac acagcggctt
    18481 atgacgcctt gattgcagaa tacttcacag ctcaagtggg tgaaagcaag cctgaaaaac
    18541 tcactttgac ttatgacctc aagcaaccaa tgcgttacgg tgagaatcct caacaagacg
    18601 cggactttta ccagaaagct ttgcctacag attactctat tgcttcagcc aaacagctca
    18661 acgggaaaga attgtcattt aataatatcc gtgatgcaga tgctgctatc cgtatcatcc
    18721 gtgacttcaa agatagtcca accgttgtgg ctctcaaaca catgaatcca tgtggaattg
    18781 gtcaagctga tgacatcgag actgcttggg actacgctta tgagtctgac ccagtgtcta
    18841 tctttggtgg aattgtcgtc ctcaaccgtg aggtggatgc tgcgacagct gagaagatgc
    18901 acggcgtttt cctcgaaatc atcattgcac caagctatac ggatgaagcg ctagccattt
    18961 tgatcaataa aaagaaaaac ttgcgtatcc ttgccttgcc atttaatgct caagaggcta
    19021 gcgaagtgga agcagaatac acaggtgtag tcggtggact tctcgtgcaa aatcaagacg
    19081 tggtcaagga aagcccagct gactggcaag tggtgaccaa acgtcagcca accgagacag
    19141 aagcgactgc tcttgagttc gcttggaagg ctatcaagta cgtcaaatca aatggtatta
    19201 tcgtgaccaa cgaccacatg acacttggtg ttggtccagg tcaaaccaac cgtgtggctt
    19261 ctgttcgcct tgccattgac caagccaaag atcgtctgga cggggcggtc cttgcttcag
    19321 atgccttctt cccatttgcg gataacgtgg aagaaatcgc caaagcagga attaaggcca
    19381 tcatccagcc cggtggctct gtccgtgacc aagaatccat cgaagcagcg aataaatacg
    19441 gcttgactat ggtctttaca ggtgtgagac attttagaca ttaagaagat aaaagggaag
    19501 aaaacagttt ctttcctttt ttggcttaaa atgctaactg aaacaagatt aaaacgaact
    19561 tttttgatat aatgttggta aataattcgc aaaagaggtt gaggaatgaa actgcttgtt
    19621 gtcggttctg gtggtcgtga gcatgcgatt gctaaaaagt tacttgaatc aaaagacgtg
    19681 gaaaaagtct ttgtagctcc tgggaatgat gggatgactc tggatggttt ggaattggta
    19741 aatatctcta tttccgaaca ttctaaattg attgacttcg caaagaccaa tgatgttgct
    19801 tggaccttta tcggtccaga tgatgccctt gctgctggta tcgtggatga ttttaaccaa
    19861 gctgggctta aggcctttgg tccgactagg actgcagcgg agctggagtg gtccaaggat
    19921 tttgccaagg aaatcatggt caaatatggt gtttcgacag cagcctatgg cacattttca
    19981 gatttcgagg aagcaaaggc ctatatcgaa aagcatggtg cgcctatcgt agtcaaggcg
    20041 gatggcttgg cgcttgggaa gggtgtcgtc gttgctgaga cggttgagca agcggtcgaa
    20101 gccgctcatg agatgctttt ggacaataaa tttggtgact caggtgcgcg cgtggttatt
    20161 gaggaattcc ttgaaggaga ggaattttca ctctttgcct ttgttaatgg tgataagttc
    20221 tacatcatgc caacggctca ggaccacaaa cgtgcctacg atggcgacaa agggcctaac
    20281 acgggtggta tgggtgccta tgcgccagtt ccacacttac cacagagtgt agttgataca
    20341 gcggttgaca ccattgtcaa gccagttcta gaagggatga ttaaagaagg tcgcccttat
    20401 ctgggagttc tttacgcagg gcttatcctg acagctgatg gaccgaaagt cattgagttc
    20461 aacgctcggt tcggagatcc agaaactcag attatcttgc ctcgcttgac ctctgacttt
    20521 gctcaaaata tcacagatat cctggatagc aaggagccaa atatcatgtg gacggacaag
    20581 ggtgtgactc tgggtgtggt tgtcgcatcc aagggctacc cgctagacta tgaaaggggc
    20641 gttgagttgc cagccaagac agaaggcgat gtcatcacct actatgcagg ggctaagttt
    20701 gcggaaaata gcagagcact gctctcaaac ggcggacgag tttatatgct ggttaccaca
    20761 gtagccaccg tcaaagaagc ccaagccagc atctaccaag aactatccca acaaaaaata
    20821 gaaggactct tctaccgaac agatatcgga agcaaggcaa gtaagtaaag atataagaat
    20881 aacgcgacgc agtcgccaaa cacgataatg gtcgtcgtgg tgaaaagacc agaacagtga
    20941 atgttctggt cagggggaaa ctttgagacc ttaggctcaa agtttaggaa tgaaaccgaa
    21001 ggtttgcttc cgcctccatc acctaagacc attatcaaaa agaaaaataa aaattcacaa
    21061 aatacgttaa tggtcgtatg gtttgcgagc gttagcgagc taatatagaa taatcaccgc
    21121 cgttgtgaaa gaacgattgg atgataatcc aatcgttcag ggaaattgga agaccttggg
    21181 tttccaattt aggcatgaga cacctttggt ggctgctgcc gtccctcaca agctaaggtg
    21241 attgttgaaa aagaggaaaa aggagaagaa atgaaaccag taatttccat catcatgggc
    21301 tcaaaatccg actgggcaac catgcaaaaa acagcagaag tcctagaccg cttcggtgta
    21361 gcctacgaaa agaaagttgt ttccgcacac cgtacaccag acctcatgtt caaacatgca
    21421 gaagaagccc gtagtcgtgg catcaagatc atcatcgcag gtgctggtgg cgcagcgcat
    21481 ttgccaggca tggtagctgc caaaacaacc cttccagtca ttggtgtgcc agtcaagtct
    21541 cgtgctctta gtggagtgga ttcactctat tctatcgttc agatgccggg tggggtgcct
    21601 gttgcgacca tggctatcgg tgaagctgga gcgactaacg cagctctctt tgccctccgt
    21661 atcctctctg tagaagataa gtccattgcg gatgcacttg ccaactttgc tgaagaacaa
    21721 ggaaaaatca cagaggagtc gtcaaatgag ctcatctaaa acaatcggaa ttatcggtgg
    21781 cggtcaactg ggtcagatga tggccatttc tgctatctac atgggccaca aggttatcgc
    21841 gctggatcct gcggcggatt gcccggcctc tcgcgtggcg gaaatcattg tggcacctta
    21901 taacgatgtg gacgccctcc gtcagttggc agaccgttgc gatgtcctca cttacgagtt
    21961 tgaaaatgtc gacgctgacg gtttggatgc cgttatcaag gatggacaac tccctcaagg
    22021 aacagatctg ctccgcattt cgcaaaatcg tatttttgaa aaggactttt tgtcaaacaa
    22081 ggctcaagtc actgtggcac cctacaaggt cgtgacttct agcctagact tggcagatat
    22141 cgacttgtcg aaaaactatg tcctcaagac tgcgactggt ggctacgatg gtcatggaca
    22201 aaaggttatt cgttcagaag tagacttgga agcagcctat gcgctagcag actcagcaga
    22261 ctcagcagac tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt
    22321 gtcaggaaat ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa
    22381 tatcctgtct aagaccatcg taccagcccg catttctgaa agtctagtag acaaggctaa
    22441 agctatggca gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat
    22501 gtttgcgact gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg
    22561 gcactattct attgaagcct gtgatttctc tcagtttgac acccatattc tcggtgttct
    22621 cggagcacca ttaccagtca tcaaactcca tgcgccagcc gttatgctta atgtcctcgg
    22681 tcagcatgtc gaggctgctg agcaatatgt gacagaaaat tcaagcgccc acctccacat
    22741 gtatggtaaa atagaagcga agcacaaccg caagatggga catgtgacct tgtttagtga
    22801 tgtaccggat agtgtggatg agcttgggga agggattgat ttttaggaca agtctatgat
    22861 acaaattatc gttaatacat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt
    22921 gtatgccagt gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata
    22981 ccccgaaaat tatttagcta tctatgatgt accgctggat acggatttga atacactaga
    23041 tcattacccg tctgtgttta ttgaaaaaga ggagtttgag tagaattctt ggtttaccta
    23101 gatagcttat tcccaacagc ttaagaagaa aggaaaaatt aacacatgat caaccgttac
    23161 tctcgccctg agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag
    23221 gtggaaatcc tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg
    23281 gctttgattc gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag
    23341 acgcgccacg atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc
    23401 aagtgggttc actatgggtt aacttctacc gacgtggtgg atactgctta tggttacctc
    23461 tacaagcagg ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct
    23521 gacaaggcca aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct
    23581 gagccgacaa cctttggtct taaattagca acttggtaca gcgaaatgaa acgcaatatc
    23641 gagcgcttcg agcatgcggc tgctggtgta gaagctggta agatttctgg tgcggttggg
    23701 aactttgcca atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt
    23761 gcccaagaaa tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt
    23821 cttgccagca ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa
    23881 tctgagcaac gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg
    23941 cctcacaaac gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt
    24001 ggtcacatga ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac
    24061 tcatcagctg agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac
    24121 cgttttggaa atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg
    24181 aactcgactt ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc
    24241 atgacccgtg agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac
    24301 caagtagact ttaaaccact tcttgaggca gattcagaag taacatcacg tctcacacaa
    24361 gaagaaatcg atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt
    24421 gaacgtcttg gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt
    24481 attttttatc gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt
    24541 ggccatgagt cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt
    24601 tttctctatt accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc
    24661 tggttggctt aggatttcta gttttggttt ttcttcagca atagcggctt gtccgttttc
    24721 atcgcctaca tgtgttacca tagttccgac ttcgactatt tgagtaacgg cttcctgtgc
    24781 tacgacacta tttacaagtg ttttcacttc cttaccatcg gcagaagtgc tcacagagta
    24841 gaagttgcta cgatgtccat tgacaccctt agtaatgact tgtgtttttc ctttgagtaa
    24901 gagtggattt tcacgagtca ctgtggtaaa tggaatttct tcttcttgga tatccagtct
    24961 aggttttacc tcagtagttg gtgcaagacc actttcatca cccttgtgag ttacaggagc
    25021 gccaacttca accacttggt ttataacttc tttggttacc tggctatcaa ggactgtttc
    25081 tgttgttttt ccattttcag tgagtacaga gatgtaatga gttcgttcac ctttgactcc
    25141 tgctgtgata atattttcct gaccagctgg gaggttagga ttttctttct tgataacttc
    25201 aaatggaatt tcttcagttc ttgtgatgag ttctggtctg gtttcaacat tggcagccac
    25261 ttcattttca tccaggcttc ctgaatgagt tgcagctggt ttgaggcctt gaagagcggc
    25321 ttttaggttg gctacaagta tgtcaagctc agcttgttta ttacggttga ggttgtaatt
    25381 tagagctgtt ttagctgcgt caagggcctc aagactttct ttactatatc cttctaagtt
    25441 tgtaggaatt ttagctaatt cttcgcggag agcattataa ttagcacgga agtagtcttt
    25501 gttgtggtct gcaaaggcag tcatgagttc aaagatttcc tcttccttgt actcagcgct
    25561 tggtctatct gcccagattg aaagcatact tccgactgtt ggaagatcta cttcaggata
    25621 tttggtagaa gctagttgat tgaatggtgt ttttccagta ttctcaatag ctttcttgag
    25681 gaaaccacca ccatcttctg gtttttgacc aagaatgtag taccagtcac cgttggtatt
    25741 caagaattta tagcctttgc ttgctaggta ttgaggtgat gcgaggttat atccccacca
    25801 gcctttagac cagtaagaaa tcaagacatc tttgtcaaac tgaacatcgt ccttgtcttc
    25861 atagtagaag ccatcgttga aggccattgg ttgaagccct ctttctttgg ccatagctgc
    25921 gagggtgttg gcatattcgg caaatttgcc atagagttga taccacttga ggtagtacca
    25981 gccttgggca ctagtcgcat cgttggcgta ttcgtcagta ccaaagttga aaatctttgt
    26041 tttacctgca aagaagtcca tgtatttacc gatgagggct tttacaaagt tcatcgcttc
    26101 ttcgtttttc aagtccatag ttgtttttga aactttatca aagtgggctt gaggattttt
    26161 aatacctaat ttttccatgg caaccagcat agcatccatg tgacctggac tgttaatagc
    26221 tgggatgaga ccgatgtcct tagatttagc gtattcaatt agctctgtca cttctgcctg
    26281 tgttagtgca gtaccgtttg gatcgtcgta gtaagcttta gttccttcga taatagcttt
    26341 tttaacgtca tcactagcat aggtttttcc gttggcagta atggtcatat catcgagtag
    26401 aaagcgaagt ccgtcatttc ctagaaggag atggacatca gaatatccga gctcactggc
    26461 cttgtctacg atgcgtttga gctggttcag agtaaagtat ttgcgtccag catcgattga
    26521 gattaccttg tttttggcaa gtttttcaac ctcacgttta gcttcttctt ctttttgagc
    26581 ttcaggcgtg agggtcaagt tgttgacagt ttcttgaagt ttagcaatgg cttgatcaat
    26641 cgtatcttgt tgggcacggc taaggttgct atcgagagag cgaatagctt tttcagcttc
    26701 ttttacggcc gtgacgcttt ctgcagtata acggttcagg tcttttggta cctcgttaag
    26761 tgcttgctct gcagattcat aatcagctgc gaagtattca gcgttggcat ttgcaaaatg
    26821 acgcatgagt ttgaagaggc gtgatggtga ataacgtgca gatggagtgt cagcccaagc
    26881 agctaccata ccaccgatga ttgggatatc agctccttct gtttttggta cagaagtgat
    26941 tggtgtgttt ttaataccat tgagcccctg atcgagattg taccagcctt ggccatcagc
    27001 gtttcgtcca agaacgtagt accaagcatc attggtatta aggatttggt gacctttttc
    27061 agctagtagt ttagaagaag cgacatcgta gcctccccaa ccaccagtcc acatagaaac
    27121 gatgatgtct ttgtcaaaac taccaaagct tgtgtcgcta ttgtagtaga taccgtcgtt
    27181 aaaggccatt ggtttgagac cgtgcgattt tacaatacga gcgaggtcat tggcgtaggc
    27241 aataaatttt tcatagcctt ttacagggta gccttcgttt ggatagtatt tatcagcttg
    27301 aagcacactc caacctttag catctgtcgc atcattggca tattcatcaa gtccgatgtt
    27361 gaagatttca gtctttttcg cgaaataagc agcatacttg tcgataaggg cttttgtaaa
    27421 agcgacagct tgttcgttgt caagatcgac agtacgggct gattccttcc caaaatagct
    27481 aaagttaggg ttttggattc ccaattcttt catggcattg agaatcgcat ccatgtgacc
    27541 aggactattt actgtcggaa tgagaccgat acctttatct ttggcatagt taatcagatc
    27601 tgtcatttga ctttctgtta agtgattgcc gtttggatcg ttgtaataat catttgtacc
    27661 tttttcaatg gcgcgtttga catcgtcact ggcataggtc ttgccgttag ctgtgatgct
    27721 catatcgtcc aacatgaaac ggagtccatc atttccgact aataggtgta aatcagtgta
    27781 gccataatgt ttcgctttat cgatgatttt cttgagctgt tctggtgaga aatatttacg
    27841 tccagcatca atagaaacaa ttttcttttt cgctagtttt tcatttacag ttgcagcacg
    27901 ttcctttcct gcctctgttg ccggtttgtc agcctctgct ttcgcttcat cttttttagc
    27961 tggtttatcc ttgtcagtct tgtctgtatt tgactcttta gaatcaacct ctttcgcttc
    28021 ttccttttta gggctagctt cttctgcctt tttattagca gtttcttttt cagcagaagt
    28081 tggagttacc acttctgctt tatcactagg agttgaacta acttcctctt gtggtttttc
    28141 ttctgttttt ggaagactag ctaccttatc agtagctgga gtttctgttt ctacagtttt
    28201 tggagcttct ggttgaagct ctgctttagg tgtttcctca gtccgatttt cggatgattg
    28261 aggggaatca gaaaccgtat ggatggtcgg ttggttttct gtagtagtag gagtaactcc
    28321 atcggctgca acagtctgtg cttggaaggc aaatccaatt agaacagaag ctgctcctac
    28381 agcgtattta cgaatagaaa aacgctgttg tttttcatgt ttcattgcaa aacctcctga
    28441 ttgcattgtt atattgatag cgattatata aatcaacgcc cttattttat ttcttatatt
    28501 aacgagagtc aagaggagat gacaaaaaac tataataagt ataaaaaaat ataaaattta
    28561 aacttaagat ttcagattgg tc
//
LOCUS       DAVKMO010000022        26223 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVKMO010000022 DAVKMO010000000
VERSION     DAVKMO010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26223
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.022"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(112..387)
                     /locus_tag="VW361_001115"
     CDS             complement(112..387)
                     /locus_tag="VW361_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU9744165.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="VW361_001116"
     CDS             complement(494..1333)
                     /locus_tag="VW361_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9744166.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="VW361_001117"
     CDS             1475..2323
                     /locus_tag="VW361_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9744167.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILGWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="VW361_001118"
     CDS             complement(2416..3333)
                     /locus_tag="VW361_001118"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU9744168.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3771..3976
                     /locus_tag="VW361_001119"
                     /pseudo
     CDS             3771..3976
                     /locus_tag="VW361_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4287..4580)
                     /gene="rpmA"
                     /locus_tag="VW361_001120"
     CDS             complement(4287..4580)
                     /gene="rpmA"
                     /locus_tag="VW361_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU9744169.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4597..4941)
                     /locus_tag="VW361_001121"
     CDS             complement(4597..4941)
                     /locus_tag="VW361_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU9744170.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENS
                     SEFVQTRVITEN"
     gene            complement(4957..5271)
                     /gene="rplU"
                     /locus_tag="VW361_001122"
     CDS             complement(4957..5271)
                     /gene="rplU"
                     /locus_tag="VW361_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU9744171.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5308..5395)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5490..6089)
                     /locus_tag="VW361_001123"
     CDS             complement(5490..6089)
                     /locus_tag="VW361_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU9744172.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDIR
                     DKLLTLIAFMMGVFLLTIYKEKLRIVKKSILSLIPLAILSIIIGFVPQTVDNIYLVPP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGVVFSVYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6560..6859
                     /locus_tag="VW361_001124"
     CDS             6560..6859
                     /locus_tag="VW361_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU9744173.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7079..8092
                     /locus_tag="VW361_001125"
                     /pseudo
     CDS             7079..8092
                     /locus_tag="VW361_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436461.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8408..9382)
                     /gene="pta"
                     /locus_tag="VW361_001126"
     CDS             complement(8408..9382)
                     /gene="pta"
                     /locus_tag="VW361_001126"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU9744174.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(9426..10322)
                     /locus_tag="VW361_001127"
     CDS             complement(9426..10322)
                     /locus_tag="VW361_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9744175.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(10319..11137)
                     /locus_tag="VW361_001128"
     CDS             complement(10319..11137)
                     /locus_tag="VW361_001128"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU9744176.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(11121..11792)
                     /locus_tag="VW361_001129"
     CDS             complement(11121..11792)
                     /locus_tag="VW361_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU9744177.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            11920..12489
                     /locus_tag="VW361_001130"
     CDS             11920..12489
                     /locus_tag="VW361_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU9744178.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            12602..13561
                     /locus_tag="VW361_001131"
     CDS             12602..13561
                     /locus_tag="VW361_001131"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9744179.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            13571..14686
                     /locus_tag="VW361_001132"
     CDS             13571..14686
                     /locus_tag="VW361_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9744180.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLKAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            14691..15038
                     /locus_tag="VW361_001133"
     CDS             14691..15038
                     /locus_tag="VW361_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU9744181.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            15046..15261
                     /locus_tag="VW361_001134"
     CDS             15046..15261
                     /locus_tag="VW361_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9744182.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGKKVYQGLVGDLYRFLSHADFLHQN"
     gene            15344..15985
                     /locus_tag="VW361_001135"
     CDS             15344..15985
                     /locus_tag="VW361_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU9744183.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            16003..16692
                     /locus_tag="VW361_001136"
     CDS             16003..16692
                     /locus_tag="VW361_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9744184.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(16689..17369)
                     /gene="radC"
                     /locus_tag="VW361_001137"
     CDS             complement(16689..17369)
                     /gene="radC"
                     /locus_tag="VW361_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU9744185.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(17412..19703)
                     /gene="pcrA"
                     /locus_tag="VW361_001138"
     CDS             complement(17412..19703)
                     /gene="pcrA"
                     /locus_tag="VW361_001138"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU9744186.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDSDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(19895..20698)
                     /locus_tag="VW361_001139"
                     /pseudo
     CDS             complement(19895..20698)
                     /locus_tag="VW361_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004897104.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(21079..21939)
                     /locus_tag="VW361_001140"
     CDS             complement(21079..21939)
                     /locus_tag="VW361_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU9744187.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(21955..23232)
                     /locus_tag="VW361_001141"
     CDS             complement(21955..23232)
                     /locus_tag="VW361_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9744188.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(23225..23776)
                     /locus_tag="VW361_001142"
     CDS             complement(23225..23776)
                     /locus_tag="VW361_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744189.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(23792..25051)
                     /locus_tag="VW361_001143"
     CDS             complement(23792..25051)
                     /locus_tag="VW361_001143"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9744190.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGTSVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         8047 a         5600 c         4646 g         7930 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctaaatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag ggagctcaac aagccagtta cacggccaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag gttggaagat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccggctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggcgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatctcga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattgt acgaccacga gcattaccat gaactaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatctgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggcaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aggcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgct tatgtatgaa aaagcaatgc aactaactcc tgagaacttt aaattactaa
     3601 ttggtgccga aaaggtagaa tttagaatcg aggtacacct atggctgtaa aatttacaaa
     3661 atgagacaac ttgggcaaga tgtttgaaga atttcctaaa ctccctgatt tgaagcaagt
     3721 cactttccct gatgacaaag aaaaaagcca aagcaataaa gaaaaactag atgactgctt
     3781 tccaacaact cccatctagt gtgcttcaga ctgggctatt tttctttcca tctgttagct
     3841 tggattctca gaccgtttca gctaaagaat atcttttcct ttatcagaag gaacggctca
     3901 agccattcag acaagtgaag ggacgacaag ccaatatttg aaaccaggta gcagttctta
     3961 tagtcaattg aaataaaatc tgaagaaatc gagtaggaaa cttaaatcaa tttttagcag
     4021 tgttctattc cagattcata ctcaatgaaa attaaagtgc aaactaggaa gttagccgca
     4081 ggctgtactt gagtacggca aggtgaaact gacgtggttt gaatttgatt ttcgaagagt
     4141 atcaatccac tatacatatt aaaaagtatg ggtaccaaaa caaaaaaaca ggctctccga
     4201 aaactcggaa agccttattt taagctgttt ctagcttcct cacctttaca tttcaaggtt
     4261 cgggataaaa ggttcaatgg acctttttat ttagcgattg ggtaaacaga aacttgtttt
     4321 ttatcgcgtc ctttacgttc aaagcgtact acgccttcaa ctttagcgaa caaagtatcg
     4381 tctccaccac gaccaacgtt tacacctgga tagatgtgtg taccacgttg acggtaaagg
     4441 attgatccac ctgttacagt ttgtccgtca gctgctttag ctccaagacg tttcgcttgt
     4501 gaatcacgtc cgtttgatgt agaacctcca ccttttttgt gggcgaaaag ttgcaagttg
     4561 ttaagagtca tttttaacat aatgttttcc tccgtgttag ttttctgtga taactctggt
     4621 ttggacgaac tcagaagagt tctccgataa gtttgccata cctaagaaaa atgattcaaa
     4681 gaataactgg gtcatttctc tctggtgtga aggaagatct tttggtattt caaccatcag
     4741 atagccacct tcatcttcgt ttaattctag gattggttca tagcctgcaa atttctcaat
     4801 agaattgata aagttaatgg caagcgtaga aaccgatgca cacacgacat ctaagccgta
     4861 ttcgccactc tcggcgtgtc cagtaatttc cgcactcctc agctcgccat cttcggctct
     4921 ctcaaagact gcttgtatca tgtgttctcc ttaaaattaa gcgttaattg cgttgatgac
     4981 aacttttgta tatggttgac ggtgaccttg tttacggtgg ctaccttttt taggtttgta
     5041 cttgtaagta acaactttct tttgttttcc ttgtttttca acagttccaa ctacagtagc
     5101 tccagcaaca agtggagttc cgacaacagt gttttcacca ccaacaagaa caacttcgtt
     5161 aaaagtaact tcttgaccag cttcaacgtt caatttttca atgtaaactg cttgaccaac
     5221 ttcaacttta acttgttttc cgccagtttt gataattgcg tatgtgctca ttatgcacct
     5281 cctatgattt ttatgggttt ccccgatttt tttgtgaaga ctcgcctagc atcgtgggac
     5341 aaaccactta aacttgaata atcaagcaac gatgttcgtg cggttgcaca ggatcgtgca
     5401 tagtcaactc ttcaagtgta gcatatttcc tattttctta caagtaataa cacctaaaat
     5461 caagcttttt cttttacttt tttctgccac taggcaaaaa gcatactgag ataaaaaatg
     5521 ctcatcataa taggaacacc aagaatggtc ttttcatgat agaaaatcgt caaatagact
     5581 gaaaagacaa cgccaaggac aaaactacta agcaggctaa caaatatgaa cccttcacgc
     5641 aaaaaaggag tgtgcttagt tcggaaataa tctccaaaag ctagcattgt tcgtttgata
     5701 ttccctgtca taaaggcatt attgtaggca atacccgaaa cctcaccaaa agcagttgtc
     5761 accagtccca tacagaaggc caagggcggc actagataga tattatctac agtttgtggc
     5821 acaaaaccaa taattattga taggattgct aaaggaatca aggacagaat agattttttc
     5881 acaattctca atttttcctt ataaatcgtt aataaaaaga ctcccatcat aaacgctatt
     5941 aaggttaaaa gcttatccct aatatccgaa acattatttt gtatgagctc taccgaaaga
     6001 aagacaacat ttccagcttg tccagctaca agggtattcc cgcgaacaat aaaagtgtaa
     6061 gcatccacat atccagcaca aaacgtcaaa aaagtgctaa ccttttagac tgacgtgata
     6121 tttttcttat aggtaataac ctcattttcc ctcccattgt attttctctt agaaatattg
     6181 taccattttc tttctaaaaa atcgtaggct accatttaga ttttactatt agcataaaaa
     6241 taataataga caactattta tccaaaaata gatagaggta acatgtttgc aaacaaagca
     6301 tacgaacctt tagtaaaatc atttccatga aactagaata gagcccctct tagcaaaaat
     6361 cattatttta atttatttct aatcactcct tgacataaat aactctcacc aataaaagac
     6421 tatgtcttaa aaaaatggta taataaaatc aatacttggg cttgatggct atgctactaa
     6481 taacaattag gagagaaaat caggcacttg ttaacaacaa ggattatccc cttgagatga
     6541 aaggaacttt agaaatctta tgatgaacat gcaaaacatg atgcgtcaag cacaaaaact
     6601 tcaaaaacaa atggaacaaa gccaagctga acttgctgct atgcaatttg ttggcaaatc
     6661 tgctcaagat cttgtccaag caaccttaac tggcgataag aaagttgtca gcattgattt
     6721 caatccagct gtcgttgacc cagaagacct tgagactctt tctgatatga ccgttcaagc
     6781 catcaactct gctcttgaac aaatcgatga aactactaag aaaaaactgg gtgctttcgc
     6841 tgggaaattg ccattctaaa aacaaggagc tagaacaatg cttgtcgata acaaaggcta
     6901 agaaaggtgc aaaaattata aaaaacgcat agtatcaagc aacctaaaac tttgggctct
     6961 ataatatttg tagtgggtaa atcccctatg gatattatgg agcctatttt tgtgtagaaa
     7021 aaaagtccca tatgacctat aatgaaaagc gacaaaacaa ctcattagaa agaatcatat
     7081 ggaacaatta cattttatca caaaattact agacattaaa gaccctaata tccagatttt
     7141 agacatcatc aataaggata cacacaagga aatcatcgcc aaactggact atgaagctcc
     7201 atcttgtcct gagtgcggaa gtcaaatgaa gaaatatgac tttcaaaaac cttctaaaat
     7261 tccttatctt gaaacgactg gtatgcctac tagaattctc cttagaaagc gtcatttcaa
     7321 gtgctatcac tgttctaaaa tgatggtcgc tgagacttct atcgtcaaga agaatcatca
     7381 aattccttgt atcatcaacc aaaagattga tcagaagcta attgaaaaga cttctatgac
     7441 cgacattgat catcagttgt ctatttcaac ttcaactgtc attcgcaaga tcaatgattt
     7501 tcactttgag catgattttt cgcgtcttcc tgagattatg tcctaggacg ttgaaacagt
     7561 ctggggagtg actgtttcaa tcgggagata gagatgagct ttattgctca ggactttgat
     7621 aagctcaata tcataactgt tcttgagagc agaacacaag ccatcatccg aaatcccatg
     7681 aatacaaggc tatcaagcga tactgaaagc tcattcaaca agatagtcag aaactgagtg
     7741 ataaacgatt ttatcgccct acttttcgta tgcacttgac taataaagaa attctagata
     7801 aacttttgag ctattccgaa gacttgaaac accactataa tctctatcag ctcttgcttt
     7861 tccacctctt tttcagactc tgtttaaaac cttcctcaaa gataaagaga aaatcgtcaa
     7921 cgcccttcaa ttaccttatt ccaacgccaa actggaagcc accaataatc tcatcaaact
     7981 tatcaagcac aatgcctttg gttttcgaaa ctttgaaaac ttcaaaaaac ggatttttat
     8041 cgctctgaac atcaaaaaag aaaggacaaa atttgtcctt tctcgagctt agcttttctt
     8101 caacccacta cagttgacaa agagccagaa aacgcataat agcaggtgtc aagacactta
     8161 atattatgcg ttttctcatg aaaaaattct cttttcatac tcatttaaaa tcaaaaaggg
     8221 aatttatcgt tttacggaca tgtatattac agatttctat aggtcgtgta tagacaggat
     8281 atcatcgctt ggaagttttc ctttttgaca ccaatcagta atttagttct caggaattaa
     8341 tggcagtgct tttcgtacat agtttcataa ctacagtata gcatagtata tcgctttata
     8401 gttttcacta ttgatgaact gcttgagctg ctgtgatgag ggtcaacttg taaacatcat
     8461 ctgcattaca tccacgagaa agatcattaa ctggcttgtt taaaccttgc aaaacaggtc
     8521 ctacagccgc aaagccaccc aggcgttcag ccatcttgta accgatattt cctgcctcga
     8581 tacctgggaa gatgaagaca tttgcttgac cagctaccgt acttccagga gctttcagag
     8641 ctgcagtttc aggaacaaag gctgcatcaa attgcaactc accatcgatt tcaaggtcag
     8701 gacgcaagtc gtgagcaatt ttagttgctt caacgacctt atcaacgctt tcaccaaacc
     8761 ctgagccttt agtagaatag ctcaacatgg caattttagg ttcgatgcca aacatcttag
     8821 ctgtgattgc tgagttgatg gcaatttcag ccaaggcttc tgcatctgga ttgatgttaa
     8881 tggcacagtc tccaaatagg taacgttccg taccacgaac catgaggaag gctcctgaag
     8941 tacgagttac atttggacga gttttgatga tttgtagagc tggacgaact gttgaagctg
     9001 ttgagtgaat cgctcctgac accattccat caaccaagcc caagtaaacc aacatcacac
     9061 caaagtagtt gacatcttca accaaaacct tgcgtacatc ttcttcagtc attttgccct
     9121 tgcgacgctc caccaaggca gaaaccattt cttcaaattg aggataatgt tgagggtcga
     9181 tgacctcata accatccatg attccttcaa tttcaagata aattttaatt ttttcaggat
     9241 ttccaagcaa aacaggaatc acttctgttt cttttactaa gcgttttgtt gcttgaagaa
     9301 tacgaggctc ttccccttca gggagaacga tacgagcatt tttaccaaca aggttggctt
     9361 tgagactttc aaaaacttcc atgagttttc tcctttaaga taataattat actctgagac
     9421 agtttttata gagtattagt tgataactgg gtaataaggt tactgaaatc atccggcaag
     9481 ggactttcta actgcaagtc ttgctctaaa aatggatgat aaaaggatag gtaatggcaa
     9541 tgcagagcct gacgttgaat accatcttcc agactaccac catacaaatc atctcccagc
     9601 aaaggaaaac cgatatgaga aaaatggact cggatttgat gggttcgacc agtgtgcagg
     9661 tgaatataga ccaagtgaat atttccataa gaagctacaa tcttgtatga agtatgggca
     9721 tactttccgc ctttagccac tcgtctggta ataatggaat cttcatcacg cgcaatcgga
     9781 gcaataattt ccccttctgg ctccaaatgt ccatctccct taaccaaagc aaagtagcgt
     9841 ttctcgatag atttcttctg caactgcttg tctaatcgtg catgggcata accgtgcttg
     9901 gcaaagagca tcaagccaga agtgtcccta tctagtctgg taacaatgtg aacctgctga
     9961 ttttcataat tttgcttgac atagtaaccc ttgataaaat tggcaatggt attagagtga
    10021 ttgacactag gaatagaagc cactccatag ggtttattca agactagaaa gtggtcatcc
    10081 tcatagagaa tatctaatgg atgctcaata gcctccaagg tttcaaagcc ttcctcagcg
    10141 ggaatgtaaa tggtaacgta gtctccaacg tccaatagat acgttgcatt ttgcggttga
    10201 ttattgacca gaatagctcc acctcgaaac ttaatcttag ccagcaatcc cttagaaacc
    10261 tcgtgctttt ttaaaaaggt cttaaccttg acatgttcat ctgcgataaa ttcaaacctc
    10321 attcatccac ctcaccgata aaggcatcct taacacggtt ccagaaactg gtatggctag
    10381 gagtcgcgac aaagtgaatc ttatgatggt cgatttgata ctcaatacgc tcaatattac
    10441 ggaaagaata aacgctattg tcaaccgaaa tagtatgata atcgtttctt gttggaataa
    10501 gttcaatctt atccttctta ggcacaataa tggaagagcc cagtgttcga taaacacgat
    10561 tattaaggct ggcaatttcc gttaattgca aagcttcaat ggtagggtgt aaaacagcac
    10621 cgccaagaga cttgttatag gcagtactac cagtcggtgt cgaaactgtt agcccgtctc
    10681 cacgaaaacg ttcaaaggga acaccattta ttacaatatc tgccaccatg gttcgatcag
    10741 acctgcggat gctggcttcg ttgagtgctc tgaaaatctt aacttcacca ttttcaagaa
    10801 agaccttcac attcagaaca gggtaagaaa cccttgcccc agtatctagc tgcaaattag
    10861 tcactagctt gtccaactca aaatcacgat aatctgtata gaagcccaaa tgtccagtat
    10921 gaagaccgat aaagcggacc ttgtcaagct gattttcgta cttatgaaag gccgacaaga
    10981 gcataccatc cccgccaatg gaaatgacaa tatccggatt ggtatcattg agtataaact
    11041 gatttctctt caaacgatct cgcaattcat acaaaaccct ttgactctgc ggttttctat
    11101 tggctatcag atcaattcgt ttacctgtat tcttcatctg tatcgtcact gtttcctaca
    11161 ccgtcattta attttctact caaaggatca aaaagtgcct gggcttcttg gatatcatca
    11221 cgaatttcac ccatttcttc atccaactga tgggcgattc tagctgtaat ttccagtcgc
    11281 ttcttaatct catctgggaa atccccttgg tacttgtagt tgagagaatg ttctatcgtt
    11341 gcccagaaat tcatggccaa agtacgaatt tgaatttctg ccaaaatagt cttagctcca
    11401 ttgatggtat caaccgtata ttctactacc acatgatagg aacgatagcc tgatgctttt
    11461 ctatgagtaa tgtaatctcg ctcctgtatg attcgcatat cctgacgctt gtgcaaaata
    11521 tccactactt ccttgacgtc atctacaaac tgaaccatca cacgtaagcc agcaatatcc
    11581 tgcaaatcgt gttccaaggt cgcataagta atgccacgac gagccatttt ttctttgatg
    11641 ctctcaattg gcttgactcg accggtcaca aactcaattg gagaatgctt attttgctta
    11701 cgatattgct tacgaatacc acgaagttta atctttaact caccaacagc ttgaatgtaa
    11761 ggatctagaa attcttccca ttctaaggtc atatattctc ccttgttctc atattatccg
    11821 tcaaaaatat ctttgatttt ttctccagat tcatatacaa taaatacaat gcttattata
    11881 ccataaatcc gctttcaacg ataaaaaaag gtaagaaaaa tgaaacattt agaaattgaa
    11941 ttgaaaacac tattgaaaaa agatgaatac aatcgtctaa aagaccagtt cacaggtgtc
    12001 actcctgttc ttcaaacaaa ttactacata gacacgcctg attttgaact gcgagaaaag
    12061 aaagtcgcta tgcgcattcg aacctttgaa gactgggctg agttgacact caaagtcccg
    12121 cagagtgttg gaaacatgga atacaaccaa aaattgcaac taaaagatgc tgagaactat
    12181 ctgagtaagg aagaacttcc tcaaggacta gtactggatg aattggcgaa acatggtatc
    12241 caaagtaaga actggcaggt tcttggttgt ctaacaacgc ttcgctatga aatgaaaaca
    12301 gctattggtc tcatggcact ggatcagagc cgatactttg atatgacaga ttacgaattg
    12361 gagcttgaag tggaaaatca tgagcaaggc aaacaggatt tccgacaatt tttagagaaa
    12421 aatcagattt cctaccaaaa agctccttca aaattggttc gatttgtcaa aagtatgaaa
    12481 aatagctgaa ataatctcca ttttttggta aaatagaaaa gataaaaata cacaaaccct
    12541 agttcatata tgtaaggtaa atataactag gatttataaa gtttacagag gacggtctat
    12601 aatgtcagat agaaaaaaca tgaaactttt cgcacttaac tctaaccaag agattgcaca
    12661 gaaaattgcc caagctgttg gtgtcccact tggaaaacta tcatcacgtc aattttcaga
    12721 cggagaaatc caagtaaata tcgaagaaag tgtccgtggt tatgatgttt acatcatcca
    12781 atcaacaagt ttccctgtca acaaccacct aatggaactg ttaatcatgg tcgatgcttg
    12841 tgtgcgtgca agtgcccaca gtatcaacgt tgtccttcca tattttggct atgcacgtca
    12901 agaccgcatt gcttgtcctc gtgagccact tacagcaaaa ctagttgcca atatgctggt
    12961 taaggctgga gttgatcgta tcctgactct tgatttacat gccgttcagg ttcaaggttt
    13021 ttttgatatt ccagtggata atcttttcac tgttccccta ttcgcaaaac attactgcga
    13081 taaaggattg cttggttcag atgttgttgt cgttagccct aaaaattcag gtgtcaaacg
    13141 tgcgcgtagc ctggctgaat atcttgatgc tcctatcgcc attatcgact accctcaaga
    13201 cgatgcaact cgtaacgaag gttatattat tggtgatgtt gaaggtaaga aagctatctt
    13261 gattgatgat attttaaata caggacgtac cttctctgaa gcttctaaaa tcgttgaacg
    13321 tgaaggagct acagaaattt atgctgtttc tagccacggt ctcttcgtcg agggagctgc
    13381 tgagcttctt gacaatacta atattaaaga aattcttgtg actgattcag tagcaacaaa
    13441 agaaaaaact cctaaaaatg tatgctacat cactgctagt gagttaattg gtgatgctat
    13501 cgtccgtatt cacgaaagaa aaccagtcag cccactcttt gcctacaata aaaagaaata
    13561 aggtgattct ttgatttatt tggacaatgc tgcaacgact cctatgtcag cagttgctat
    13621 ttcagctatg accaaggtta tgcaagaaac ccacggaaat ccttctagta ttcatggtca
    13681 tggtcgtcaa gctggcaaac tcttgcgaga agcccgtcag gaactagccc agttactaag
    13741 gacaaaacct caacatatct ttttcacttc tggtgggact gaaggcaata atactaccat
    13801 cattggctac tgtcttcgtc accaagaaca aggaaaacat atcatcacaa ctgccatcga
    13861 gcaccatgct gtccttgaaa caattgatta cttggttcaa cactttgggt ttgaagcaac
    13921 cattatccag ccagaaaatc aagaaatcac agcccagcaa attcaaaagg ctttacgtga
    13981 cgatacgatt ttggtttcta ctatgtttgc caataatgag acaggaaacc tacttcccat
    14041 cgctgaaatt ggccaaatac tcaagcaaca ccctgctgcc tatcatgttg atgcagttca
    14101 ggctattggt aaaatcccaa ttcattcaga agaattgggc attgattttc tcactgcttc
    14161 tgcccacaaa ttccatggtc ctaagggaat cggttttctc tacgcatcta gcatggactt
    14221 tgattcctat ctacatggcg gagatcagga acagaaaaaa cgtgcaggaa ctgaaaatct
    14281 gcctgccatc gtaggcatgg ttgcagccct aaaagaagac ctagaaaaac aagaagaaca
    14341 ttttcaacat gtacaaaatc tagaaactgc ctttctggca gagctggagg gcattcagta
    14401 ttacttgaat agaggaaaac atcatctccc ttatgttctc aatattggat ttcctggtca
    14461 gaaaaatgac ctcttactcc ttcggctaga tttagctgga atttcaatct ctactggctc
    14521 agcctgtact gcaggcgttg tccaatccag ccatgttctt aaagccatgt atggcgcaaa
    14581 ttcagaacgc ttgaaggaat cccttcgcat cagtttgtcg ccacaaaata ccgttgaaga
    14641 cctacaaacc ctcgcaaaaa ccttaaaaga aattatcgga ggttagccat atggcatttg
    14701 aaaaaatcat tcagttaaaa aattgtcgtt acgattacac tcttagccct tctgttaaaa
    14761 aattcaccct caaagataac accttttttg aaactaaggt tggtaactat gaactgactc
    14821 gccttttgga aaaagtgcca aacagcggtg aaggcttcca actcaaaatc atcattaaca
    14881 aggaacttac aggggctaaa atcaatatca ctgacaagtt tggccttcgt ctagttgata
    14941 ttttcaaatc agaagaccac catattcatc aggaaaaatt ctacttcctc atggatagct
    15001 tggtagaacg tggtgtcttt acaaaatcgg aaagatagag ccaaaatgtt tgaactgacc
    15061 tataaggact gctatcatgt agagcgtact ctcaagtatg aggatcatga ggctctcatg
    15121 ttgactttgt caggatgtgt aaccttacca gatacacttt atgtgacttc tctgactttt
    15181 aggggcaaaa aagtttatca ggggctggtc ggagacctct accgttttct atctcatgca
    15241 gattttttac atcaaaacta agatttttct tagttttttc ttatttttgt tgattttttc
    15301 acaatgtttc tataaaatag aagaatagaa aggttgtgat tttgtgaaag ataaacagtt
    15361 tgctattcca aaagctacag caaaaagact ctctctctac tatcgaattt ttaagagatt
    15421 tcatgcagaa aagattgaac gtgccaactc taagcaaatt gcagaggcta tcggtattga
    15481 ttcagcgacc gtacgtcgtg atttttccta ttttggtgaa cttggtcgtc gtggttttgg
    15541 ctatgatgtc aaaaaactaa tgacattttt tgccgatttg ctcaatgaca actctattac
    15601 caatgtcatg ctggttggta ttggaaatat gggccatgcc cttctccact accgcttcca
    15661 cgaacgtaac aagatgaaga ttatcatggc ctttgaccta gacgaccatc ctgaagtcgg
    15721 tacccaaact cctgacggga ttcccattta cgggatttct cagatcaagg ataaaatcaa
    15781 ggatgctgat gtgaagactg ctatcctaac tgttcccagc gtcaagtcac aagaggttgc
    15841 taatctcttg gttgatgctg gtgtgaaagg aattctcagt ttttcaccag tccatctgca
    15901 tttaccaaaa gacgtggtcg ttcagtatgt cgatttgaca agtgaactcc aaaccctcct
    15961 ctacttcatg cgaaaagagg attagaaagc gaaaatcatt ttatgaaaaa accagttatt
    16021 gggattacag gaaacgaaaa aactcatcca gatgatgaca tcatgatgag ctacgcagca
    16081 aaaggctttg ttgaaggcgt taaagatgct ggagggattc ccatcatcct accgattggt
    16141 gatcaagaaa tggcctgcca ctatatcagt ttgattgaca agctcatctt gacaggtggg
    16201 caaaatgtcg atccaaaatt ttatggcgaa cccaaaacca ttgatagtga tgactatcac
    16261 cttcaaagag atatcttcga actggccctc atcaaggaag ctattaaaca gaaaaagccc
    16321 attttctctg tctgccgtgg tacccaactc tttaacgttg ccatgggtgg aactttgtac
    16381 caagatatcg aagaccattg gcaggattct tctgttgagt acacaactca acgcttggta
    16441 acagaaccag ataccgttct ccaagaaatc tatggagaaa tctctcatat caactccttc
    16501 caccaccaga gcatcaagga cttagcacca aatttaaaag ttgtggctca tgatcctaaa
    16561 gatggtatca ttgaggctgt catgagtacg gatgatgtcg cctttctcgg tgtccaatgg
    16621 catccagaac ttctttttga aaatcgtccc aaagataaaa aactctttga ctatgtcgtt
    16681 aatgaacttt agattaaatc tgtcttttca cgataactaa agtaattaga atgagagaca
    16741 atcaaatggt ccaagagaac aatccccatc aattcgcagg cttctttaac aagtttagtg
    16801 acatgatcat cattttggct aggcgctacc gctcctgaag gatgattgtg gaccaagata
    16861 agagaagtcg ccatatgctt gattgcatag tgaagaatct ctcgcggttc agcgatacta
    16921 cgagttacag acccgataaa aatggtctgc tgatggatga tttgattttg agtattgaga
    16981 tagagtgcca ccaggtgctc ttgtttttta tcccctaatt cctgctgcat cttcttggcc
    17041 aacttttgac tgctgagaat actttccatt tcaagagtct cgtgtttgtg aatacgatgc
    17101 cccagttcaa tcatagcttg taattctatg gccttaacac gcccaatacc agacaaactc
    17161 tgcaattcct gcagggtcat ttttttcaaa tccgttaggc ttgaaagatt gttcaagact
    17221 ttttgggcaa tttcaaaaac gctagcttga cgtgttcctg tcctgagtaa aatagctagc
    17281 aactcttggt tactaagcgc ttcaactcct tccttggcca gcctttctct tggtaatagt
    17341 gaatcttctt ggaatgaaat actgtacata aaaatcctcc tcactttatt attcgtgaga
    17401 aggatggaaa attagatttt tttctcaatt ggagccacac tggctaaaag ttttttcaaa
    17461 cctacttctg ggaaattgat tttcaattcc tgcctagcac cgctacctga aacttccaga
    17521 acggttccct ctccccattt cttgtggaga gcaatatcac caatggacca atttgcctcg
    17581 ctagatgctg gttttgcgcc agctgtaaat tgaccaaatg gaagaccgct tgactggatt
    17641 gattttgggg cagcaccgcg tttacggtct tgaagagcct gagccaaact cataccttga
    17701 ccaaaggaaa tactaccact gctatatgat gccttaaagc ttgtatttgc aggacgagcc
    17761 agaccttgat actcaagcaa gtctgaactg atttcgttaa taaaacgagt cggacggtta
    17821 taattggtac gaccaaaaag caagcgtgag ttggcattgg tcagatagag aattttctct
    17881 gcacgcgtga tacctacata ggctagacgg cgctcttctt ctaattcatc tgaatcttca
    17941 gtcgcacgac taagtggaaa gacattttct tccatcccaa tcaaaaagac aactggaaat
    18001 tcgagacctt tggcagcatg cagggtcatc aaggtcactt ctgatgtctc ctgactacct
    18061 gaatctgtgt cggcaatcaa agccaagtca tttaagaaac gactcagttt gtccagacca
    18121 gtttcctctt ctgtcacatc cgtggtgtca tcaaagttct tcgtaacaga aagaaactct
    18181 tcgatatttt caacccgtgc cttgctttct agagtcgctt gggcgttaag aatatcgaca
    18241 taacctgttt tttctaggac ggactcaacc aactctgtaa tgcttaagtg gtctagctgc
    18301 tcccgcaaat caagcatcat attggcaaaa tcccagatag attgggctgc cttacccttg
    18361 ataccagaca acataatatt agcagaagca tccagcatag acatattttg caaatttgca
    18421 aaatcacgga ttttctcaac tgtacctaga ccaattccac gtttaggctc gttgataata
    18481 cgctcaaaac taatattgtc actcaaatta gcaataaggt tgagataagc aataatatcg
    18541 cgaatttcct tacggctgta gaatttggtt ccgccaacca tggtataagg aatgttagac
    18601 ttgagcaggg cttcctcaat tgtacgggac tgggcattag tccgatagag aactgcaaaa
    18661 tccttatgaa ggaagttttg actgcgacta agttcatcga tggttctggc tacaaataca
    18721 gcctcatcca gctcatcatc ggcacgatag taaacgattt gctccccatc agcgttttga
    18781 gtccagagat ttttaggacg gcgattttta ttatttttaa taacctcgtt ggccgcttgg
    18841 agaatggttt tggttgagcg gtaattttcc tccaacaaaa caaccttggc tttggggtaa
    18901 tccttttcaa agtccaagat attctgcata tcagcaccac gccaaccgta gatagactgg
    18961 tccgcatccc caaccacaca gatattttta aaacgggaag ccaagagttt gaccaattgg
    19021 tactgagcgt ggttggtatc ttggtactca tcaacgtgga tgtattggaa tttttgctgg
    19081 tagtaggtca aaacatcagg attttgatca aagagacgca aggtcagcat aatcaaatca
    19141 tcaaagtcaa cggattcaga ctgacgaagt tctttttgat aggctgtata acactgggcc
    19201 acaatttgcg tatacatatc gccagcttgg gcagcataag caacatcatc aatcaaatca
    19261 ttcttagcat tggaaatggt ccccaaaata gttcgttcat tccatttttt agggtccaag
    19321 ttcaactgtt tgagaatacg tttcatgagc gttcgctgtt caccaggatc cacaattgta
    19381 aaattacgat tgtagccaat atggtccgca tcgcgacgca aaatacgcac acacatggag
    19441 tggaaggtcg caatcagaca gtcctgagtc gctggattga ggctataagc acgctctttc
    19501 atctcacgcg cagccttgtt ggtaaaggta atggccaaga tattccaagg attgaccagc
    19561 ttttcatcaa tcaaataagc gatacggtgg gttaaaacac gagtctttcc agaaccagcc
    19621 cctgccatga ttagcaaggg accttctgtc gtttgcaccg cctcagcctg acggtcattc
    19681 attccattta ataatgcgtt catcttctct tccttactct tgaagtcaat atttctatta
    19741 tatcagaaat cagggaaaat agaaacttta cggggagtag caaaatatag tggattgaaa
    19801 ctagaatact acactgtggg tttctaaaac actcgacttt ttcacccaat tttttcataa
    19861 actagctcaa tacctcaata gacttcctgc aaaactagaa tcctagttca tgattgataa
    19921 tgccagcaat caaattcatt cgtaatccga agcgtttacg atgatttcga taggttgttg
    19981 aaaacatttt aaacgttttt actttggcaa agatgttctc aaccttgctt ctctccttgg
    20041 atagcgcatg gttacaggct ttatcttcag ctgttagcgg cttgagtttg ctggatttac
    20101 gtggagtttg tgcttgagga tatatcttca tgagcccttg ataaccactg tcagccaaga
    20161 ttttaccagc ttgtccgata tttctgcgac tcattttgaa caacttcata tcatgacaat
    20221 agttcacagt gatatccaaa gaaacaatct cccttgactt gtgacaatcg cttgagcctt
    20281 catagcgtga aatttctttt taccagaatg attcgctaat tgttttttta gggcgattga
    20341 tttttacttc cgtcgcatca atcattaccg tgtcctcaga actgagagga gttcttgaaa
    20401 tcgtaacacc actttgaaca agagttactt caacccattg gctccgacgg attaagttgc
    20461 tttcgtgaat accaaaatca gtcgcaattt cttcataagt gcggtattct cgcacatatt
    20521 gaagagtggc cataagaagg tcttctaggc ttaatttagg ttttcgtcca ccttttgcgt
    20581 gtttaagttg ataagctgtt tttaacacag ctaacatctc ttcaaaagtg gtgcgctgaa
    20641 caccaacaag acgcttaaat cgtgcatcag ttagttgttt acttgcttca tcattcatgg
    20701 aactactata ccatattttg tttcgcagga agtctaatct aaaaaaggta aatttaagat
    20761 tggcaatacg aacgttaaac agaattccat ttctcttttt agaatcaaaa cgacaatatt
    20821 gtggaatctc tacaggaaca atagactgcg acactaaaat atcctctctt agttttactt
    20881 tactaatagt atataggagg agagccctga atcctagacc ctttgttatg atgcgcttac
    20941 aaacagagtt ggaaaaaatc ttaaaagcag aaaaacgcat gatatcagcc cctaacactt
    21001 gatacaatgc gttttattat gaaaagatct actggatttt ttatcaaaat aaacttccag
    21061 tagtcttttc actttttatt aataagttcc ttcttcacct tggctagtca agataacagg
    21121 tccatctttc gtaatgacaa attggtgttc atactgacat gacaatccac cgtcaatggt
    21181 cttatgcgcc caaccagttt tcatatctgt atcaatttcc caatcgcctg tattgatcat
    21241 tggttcaatg gttaagacca ttccttcacg aagacggagt ccacgacctg caataccata
    21301 gttaggaacc attggttctt cgtgcatagt tgggccaaca ccatgaccaa ccaaatcacg
    21361 cactacaccg taaccacgac tttcagcgta ttcttgaata gccgcaccga tatcaccgat
    21421 acgatttcca acaacagctt gctcaatacc cttgtacata gcttctttgg ttacatccat
    21481 caagtttttg acttcttcgg acggtgtacc aacagcataa gcccaacatg agtctgctaa
    21541 accaccagaa tagctctgag tgtatttttt catttgttca acattgttga agtttaattt
    21601 tgagacattt aggtcagatt tagcaatggg acctcccaaa accatatcaa ctttgagcaa
    21661 atcaccatct ttcaagatat aatgacgagg gaaagcgtga gccacttcat cgttaagaga
    21721 gcaacaggta gcataaggat agtccatcat ggcaccgtca accccaatct gaagtggaag
    21781 gaaattttct tctttacaac gacggcggac atattcttca acttcccaca tatctacgcc
    21841 tggcttaatc aaatcacgta agcctatatg aatacttgct agaaaatcac cagccttgtc
    21901 catagcttcg atttcacgag ctgattttaa tgttatcatc ttttctccta gtttctaatt
    21961 aattttaaca gtcacatttg cttttgaaac aatctggtga ccatgataaa tatcgtaatc
    22021 aattatagct gaccgtctcg tatgatgaat aatccgtgcc tgaatgcgca atatatcatc
    22081 tatctgaaca gcctgcaaaa agtagatcag catctgctcg ataatgagat tgcgaccact
    22141 attaacaact aaatcttggg tcatgtgggt cagaatttct gccaatacac cattagccaa
    22201 aactccattt ttttctagca taaagggttc cactgtaatg actacttcat catggtgata
    22261 agagagcttt tgtccaatct gctcagaaaa agttggtaga gccgaaactt gggaacggct
    22321 catcttctcc atgacatctc gtcgcgtcac aacgccaagc aaagtttgat tgcttcgaac
    22381 aactggtacc atttcaaagt cttctgcgat catccgttga ctcacattgg caatatttgt
    22441 cgataatcca accaaaaata gactacgaga cataacctta tcaattgtcg tgcttggtga
    22501 tttatcacca gcgtctctca tggttacaac gccaacaacg acctgatgtt gattgataac
    22561 agggaaacgg ctgctacgat tcttacgaac caagtccaaa taatctttaa ctgtatctgt
    22621 ctctctcaga aaaccatact catgactagg gcgataaagt ttctcaactg tcagaatatc
    22681 agtcttgatt tggacatttg acaaggcttt attgatcatg gtcgcgacgg taaaggtatc
    22741 atgcttactt cttagaacag gaatcccttt ttgattggcc agtttaagca catcatcatg
    22801 aacctgaaat ccccctgtaa ccagaactgc attttcattt tccaaggcta gcaactgaat
    22861 acgggttcgg tctccgacaa tcaagagccc cccatcatga aggtaagaca agatattttg
    22921 ttcagtcatg gcaccaattg aaaacttact aaattctctc tctaaacctt cttgcccagc
    22981 cagaacctca gaagaagtca cttctgcaat ttcagcaaac gttaatctct ctatagcaac
    23041 tttctgggat ttaacacgaa ttgttccact tctaggacgg gtctccacaa ttccacggtt
    23101 ttcagcttct ttaatagccc gataggctgt tccatcacta actcctagat gattcgaaat
    23161 gctacgaaca ctgacccttt tacctactgg taattcctcc aaatagctta gaatttcctg
    23221 atgcttactc attgaactct ccttttacat accgaaattc aagataatcc cgcatttttc
    23281 ttgtgtaacg atcacttccc ttaaactgac ggaacaaact aaatccagac ttaagagcaa
    23341 ctctttggct agcttcattt tcaaggtggg taatgataga taattgtttt aagccaaatt
    23401 cctcaaaaga aagctgacaa atttttctaa caacctctgt cataaatcct tgcgaccaag
    23461 catcttttct caaaaaatag ccaagctcag cttctttttt gatttcatct agcttctcaa
    23521 atttaataga accaatcatt tgttgatttt tctggtcaca aattgcccac actcccaaag
    23581 gggacttcat aaagtaattg gccagtgcat attgactttc ttccagactt gcctgcgttg
    23641 ggaaaataaa ttgaagattt tctggatttg aagctatctc gcggaagtcc tgactatcac
    23701 taaaaaagaa aggacgcaaa tacaagcgat ccgtttcaaa aaaagaaaac attgctaatt
    23761 tggtccaaat attcataaac acctctacgg tttaatcctc aacaagtcta atatccgctc
    23821 ctaaattacg taatttttcg ataatatcag aataaccacg taagataaac tcgatattgg
    23881 taatttcagt tttaccttca gccataagcc cagcaatgac tagtgcagcc ccagctctta
    23941 agtcggtcgc tttaacactg gtcccacgta aatcacgtcc acccgtgtac aaaatatgac
    24001 catttgttgt cgaaatatcc gcatccatct ttgctagttc aaaaacatga tttacacgtt
    24061 tttcgtaaat cgtatcgaca attgtaccac gaccattcgc tcttagtaaa agaggggtaa
    24121 gcggttgttg caaatcagtt gcaaagcctg ggtaaggagc tgtcttaata ttgattgctt
    24181 tcaaattaga ctgttcctcg acaaaaatgc tgtcctcaga tacagtcatt ctcactccca
    24241 tttcttccaa cttagcaata aacccttcca ggtgttcgta aagaacatta tttatacgaa
    24301 ttcctttacc aactgcagca gctaaagata tatatgttcc agcttcaatg cggtctggaa
    24361 tcacctgatg acgtgtccca tgtaatcttt caacaccatc aataatgatg atattagttc
    24421 ctgccccacg gatatgggca cccatattat tcaagagagt agctacatca ataatctcag
    24481 gttcacgggc tgcattttca ataatagtac gaccatttgc tttaaccgca gcaatcatcg
    24541 tattaatcgt tgctcccaca ctaaccgtat ccatgtaaat acttgcacca tgaagtcctg
    24601 tatctttagc agataacttc atgttatctc cctcgtagct agcagtggca cccatagctt
    24661 caaacgcctt aaggtgtaag tcaatcggac gaggaccaag atcacatcct cccggtagac
    24721 caactgtcgc ttcaccaaaa cggcctaaga ggctcccata aaaatagtaa gatgcacgaa
    24781 gactgttaat tttaccataa ggcattggaa tattttgaac acctcttggg tcaatctcca
    24841 atacatcgtc ataacgctta acagtagctc ccatcaattc catgatttcg acaagactgg
    24901 ctacatccga aatatctgga acgcaatcca aagtcaccac atcatcagcc aagataatag
    24961 ctggaattaa ggcaacgaca ctatttttag caccactaat agtgatttca ccttgcagtg
    25021 gtaatccacc attgataaca atttttctca ttctaagttt tcaatactct ttcaagattt
    25081 ctaataaggt cttcaaaata aagtatatca taaatttatc cttttttcca tccttttcaa
    25141 ttttattgga taaatcagag ttgacgagtt agtaactgaa ttactaatac tcaatgaaaa
    25201 tcaaagatca aactaggaaa ctagccgcag gttgctcaaa acactgtttt gaggttgtag
    25261 atggaactga cgtagtcagt atcctacaca tacggcaagg cgatattgac gtgatttgaa
    25321 gagattttcg aagagtataa tctttctcga atcgctattg cccctttttt atcccctaaa
    25381 actgagtagg atctaagact agatctctta tctaagtatc ggaatacggc tgttcaacta
    25441 aattttagca agaacttctc cccttctctc agttcacaga agcgttttat acataccgtc
    25501 ctatcagaca atctatttta aagataaccg tgactcagga tcacttctat ctgtcgtttt
    25561 ctctttatag tgatagacct cacgggataa gtcgtacatc tttcctcgtg tatacaagat
    25621 ataaggacgt taaaaggtta cagtgaaaat agaaaatctt agtacgaatt caattactct
    25681 cgtgatttac gcatataggt tacgactacc tttttggact ttagagtttg agaccccctt
    25741 atccgctata tacgccttac tatcacgttc ctgttcgtaa agccacgatt tcgctatccc
    25801 ttcctctgac gattcttatt tccagcgtca gacttaaaac ggtctatccc cagaccgttt
    25861 taatccacta cctcacgata gtcaggcttg ggaatcgcta tttgactcgc cgagaacttt
    25921 gacatcagat atactataac aaattgaaat aagaatcaaa caatttaatt ttgaaattca
    25981 aatcaattta taacaatata gttgattgaa actagactag tacacctctg cttctaaaac
    26041 attgttagaa atcgatttta ctgtcctgat cgatttgttc tgttctcatt tcattttact
    26101 atattttaga agatatgctg tgctattcca gattcagttc gctatacatg cccgtcgtac
    26161 cacaaaatcc cgtgtttgat gaggcacggg atttttggct ctataatatt tgtagtgggt
    26221 aac
//
LOCUS       DAVKMO010000023        26168 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVKMO010000023 DAVKMO010000000
VERSION     DAVKMO010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26168
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.023"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..661
                     /locus_tag="VW361_001144"
                     /pseudo
     CDS             1..661
                     /locus_tag="VW361_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            790..2019
                     /locus_tag="VW361_001145"
     CDS             790..2019
                     /locus_tag="VW361_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9744191.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLRYDRVVRCRVKIITMDMFSPYYG
                     LAKQLRFHIVQHLSRAMSRVRVQIMNQFHRKFHEYKAIKRYWKLIQQDSRKLSDKRFY
                     RPTFRIHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVH
                     PIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIF
                     IALNIKKERTKFVLSRA"
     gene            complement(2100..2741)
                     /gene="plsY"
                     /locus_tag="VW361_001146"
     CDS             complement(2100..2741)
                     /gene="plsY"
                     /locus_tag="VW361_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU9744192.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            2877..4820
                     /gene="parE"
                     /locus_tag="VW361_001147"
     CDS             2877..4820
                     /gene="parE"
                     /locus_tag="VW361_001147"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU9744193.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            5240..7711
                     /gene="parC"
                     /locus_tag="VW361_001148"
     CDS             5240..7711
                     /gene="parC"
                     /locus_tag="VW361_001148"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU9744194.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLV
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            7841..8863
                     /locus_tag="VW361_001149"
     CDS             7841..8863
                     /locus_tag="VW361_001149"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU9744195.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEYATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            8919..9623
                     /locus_tag="VW361_001150"
     CDS             8919..9623
                     /locus_tag="VW361_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9744196.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            9688..10377
                     /locus_tag="VW361_001151"
     CDS             9688..10377
                     /locus_tag="VW361_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU9744197.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            10374..11297
                     /locus_tag="VW361_001152"
     CDS             10374..11297
                     /locus_tag="VW361_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU9744198.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            11312..11956
                     /gene="pcp"
                     /locus_tag="VW361_001153"
     CDS             11312..11956
                     /gene="pcp"
                     /locus_tag="VW361_001153"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU9744199.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            12124..12354
                     /locus_tag="VW361_001154"
     CDS             12124..12354
                     /locus_tag="VW361_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU9744200.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            12404..12484
                     /locus_tag="VW361_001155"
     tRNA            12404..12484
                     /locus_tag="VW361_001155"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12438..12440,aa:Tyr,seq:gta)
     gene            12494..12565
                     /locus_tag="VW361_001156"
     tRNA            12494..12565
                     /locus_tag="VW361_001156"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12526..12528,aa:Gln,seq:ttg)
     gene            12727..13929
                     /gene="rpsA"
                     /locus_tag="VW361_001157"
     CDS             12727..13929
                     /gene="rpsA"
                     /locus_tag="VW361_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU9744201.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(14014..15340)
                     /locus_tag="VW361_001158"
                     /pseudo
     CDS             complement(14014..15340)
                     /locus_tag="VW361_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            15534..16031
                     /locus_tag="VW361_001159"
     CDS             15534..16031
                     /locus_tag="VW361_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU9744202.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            16031..17686
                     /gene="dnaX"
                     /locus_tag="VW361_001160"
     CDS             16031..17686
                     /gene="dnaX"
                     /locus_tag="VW361_001160"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU9744203.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            17714..17908
                     /locus_tag="VW361_001161"
     CDS             17714..17908
                     /locus_tag="VW361_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU9744204.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            18058..18828
                     /gene="sufC"
                     /locus_tag="VW361_001162"
     CDS             18058..18828
                     /gene="sufC"
                     /locus_tag="VW361_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU9744205.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            18856..20118
                     /gene="sufD"
                     /locus_tag="VW361_001163"
     CDS             18856..20118
                     /gene="sufD"
                     /locus_tag="VW361_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU9744206.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            20129..21355
                     /locus_tag="VW361_001164"
     CDS             20129..21355
                     /locus_tag="VW361_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9744207.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDRVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            21342..21782
                     /locus_tag="VW361_001165"
     CDS             21342..21782
                     /locus_tag="VW361_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU9744208.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            21836..23248
                     /gene="sufB"
                     /locus_tag="VW361_001166"
     CDS             21836..23248
                     /gene="sufB"
                     /locus_tag="VW361_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU9744209.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(23479..24720)
                     /locus_tag="VW361_001167"
     CDS             complement(23479..24720)
                     /locus_tag="VW361_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU9744210.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIEQI
                     GNQSSQSVQFTPDSKAIPAPLEARTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            24823..25932
                     /locus_tag="VW361_001168"
     CDS             24823..25932
                     /locus_tag="VW361_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9744211.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
BASE COUNT         7991 a         4711 c         5716 g         7750 t
ORIGIN      
        1 cggatttatt tagaactaag aaatcgtgct tatctggtaa atcataaaag agttcaaggc
       61 ttgataaaag tactcaattt acaagctaaa atgcgacaga aacgaaaata aaggagacgt
      121 tggtaagaag gcagagaatc tcattcaagg ccaatttgaa ggctctaaag caatggaaaa
      181 gtgctacaca gatgtgacag aatttgccat tccagcaagt actcaaaagc tttacttatc
      241 accagtttta gatggcttta atagcgaaat tatcgcctat aatctttcaa cttcgcccaa
      301 cttagaacaa gtgaagagta tgttagaaca ggcctttaca gagaagcact acgagaatac
      361 gattctccat agtgaccaag gctggcaata ccgacacgat tcttatcatc ggttcctaga
      421 gagtaaggga gttcaagcat ccatgtcacg taagggtaac agcccagaca atggtatgat
      481 ggagtccttc tttgggattc tgaaatcgga aatgttttac ggttatgaga agtcgtttca
      541 gtcgcttaag caattggaac aagctattgt agactatatt gattactaca acaataagag
      601 aattaagata aaactaaaag gacttagccc tgtgcaatac agaactaaat ccttcggata
      661 aattaggctc tataatattt gtagtgggta aatcccctat agatattatg gagcctattt
      721 ttgtgtagaa aaaaagtccc atatgaccta taatgaaaag cgacaaaaca actcattaga
      781 aagattcata tggaacaatt acattttatc acaaaactac tcgatatcaa agacacaaat
      841 atccaaatta tagatgtcgt caatagggat tcacacaagg aaatcatcgc caaactggac
      901 tacgacgccc catcttgccc tgagtgcgga aaccaattga agaaatatga ctttcaaaaa
      961 ccttctaaaa ttccttatct tgaaacgact ggtatgccta ctagaattct ccttagaaag
     1021 cgtcgattca agtgctatca ttgttctaaa atgatggtcg ctgaaacttc tatcgtcaag
     1081 aagaatcacc aaatccctcg tatcatcaac caaaagattg ctcaaaagtt aattgaaaag
     1141 atttctatga ctgatattgc ccatcagctt tccatctcaa cttcaactgt tattcgtaag
     1201 ctcaatgatt ttcactttaa acatgatttt tcttgtcttc ctgagattat gtcttgggat
     1261 gagtatgctt ttacaaaggg aaagatgagc ttcattgcgc aagattttaa caatctcaat
     1321 atcatcactg ttcttgaggg aagaacacaa gctatcattc gaaatcactt tcttcgctac
     1381 gatagagttg tccgatgtcg cgtcaaaatt attactatgg atatgtttag cccttactat
     1441 ggcttggcta aacagcttcg ctttcacatt gtacaacatc ttagccgtgc tatgagtcgt
     1501 gtgcgtgttc aaatcatgaa tcagtttcat cgaaaattcc atgaatacaa ggctatcaag
     1561 cgctactgga agctcataca acaggatagc cgtaaactga gtgataagcg attttatcgt
     1621 cctacttttc gtatacattt aaccaataaa gagattttag acaagctttt gagctattca
     1681 caagacttga aacatcacta tcagctctat caactcttgc tttttcactt ccagaataag
     1741 gaaccagaga aatttttcgg gcttattgag gacaatctta agcaggttca tcctattttt
     1801 cagactgtct ttaaaacctt cctcaaagat aaagaaaaga ttgtcaacgc ccttcaacta
     1861 cactattcta atgccaaact ggaagcgacc aataatctca tcaaacttat caagcgcaat
     1921 gcctttggtt ttcgaaactt tgaaaacttc aaaaaacgga ttttcatcgc tctgaatatc
     1981 aaaaaagaaa ggacaaaatt tgtcctttct cgagcttagc ttttcttcaa cccactacag
     2041 ttgacaaaga gccataaatt atttgtctaa ctgtttgggg gcagtacaga actggcgttt
     2101 tattttttag gatcttgatg ggttaggttc aatccccaag ggaccaaatt ttcagtttta
     2161 tttttgatac gagctatatt gtccttatga cgaatgataa tcaaactagc aagtgctaag
     2221 ataatagcga tgaagagaga gtcatagtta ctcaggataa aaccaaaaag tggaaagagc
     2281 agaaccccga taacagccgc gatcgatgct gtgacactag acagtgaaat catactgcca
     2341 agatagagag ctccaaagaa gataatcgca aggtagagac agaagatagg cgcaaatccg
     2401 aaaatcactc cagcactggt tgcgacagcc ttaccacctt taaatcctgc aaagataggg
     2461 aaggtatggc cgataacagc caaaagtcca aagatgagag gagaaacgcc ttgtagatga
     2521 aaaataatcg gaagcagcgt tgctagggtt cctttgaaaa agtcaatcac aaaggttgcc
     2581 ataccagctt tcttacctaa aatgcggaag gtgttggtcg ttccagtgtt accagaacca
     2641 tgctcgcgta gattgatttg aaagaatact tgtccaatcc agagaccaga tggaatcgaa
     2701 cccagcagat aggctaggat taataaaact attgtaatca tactcctatt atatcatgaa
     2761 ttgggaaaga aaagcagaga atctctgctg aaattgtcac atcggagaaa gaaaaatttt
     2821 gcaaaatcct tggaaaacct gtagaatagt aaagatgaac gaataggagg ttccttgtgt
     2881 caaaaaagga aatcaatatt aacaattata atgatgatgc tattcaggtg ctagaagggt
     2941 tggatgcggt ccgaaaacgt ccagggatgt atattggatc gaccgatggc gctggtcttc
     3001 atcacctagt ttgggaaatc gttgataatg cagtcgatga agccttgtct gggtttggtg
     3061 atcgtattga tgtaactatc aataaagacg gtagtctaac ggttcaagac catggacgtg
     3121 ggatgccgac aggtatgcac gctatgggaa ttccaactgt tgaggttatc tttaccattc
     3181 ttcatgccgg agggaaattc ggtcaaggtg gctataagac atcaggtgga cttcacggag
     3241 tgggttcttc cgttgttaac gccctttcta gctggttaga agttgaaatt acccgtgatg
     3301 gcgcagttta caagcaacgt tttgaaaatg gtggaaaacc tgtcacgact ttgaagaaaa
     3361 tcggtacagc acccaagtct aaaacaggca ccaaagttac ttttatgcct gacgcgacta
     3421 tcttttctac gacagatttc aagtacaata ccatttcaga gcgccttaat gaatcagcct
     3481 ttctcttgaa aaatgtgacc ttgtctttaa cggacaagcg aacagatgaa gcgattgagt
     3541 tccactatga gaatggagta caagattttg tttcttatct caacgaagat aaggaaatct
     3601 tgacgccagt tctttacttt gaaggggaag acaatggttt tcaagtggaa gtagccctcc
     3661 agtacaatga cggattctca gataacattc tatcctttgt caataacgtt cgcaccaagg
     3721 acggtggaac gcacgagaca ggactcaagt ctgccattac caaggtcatg aatgactatg
     3781 cacgtaaaac aggtcttctc aaggaaaaag ataaaaacct tgaaggttca gactatcgtg
     3841 agggactagc ggccgttctt tctatcttag ttcctgaaga acacttgcag tttgaaggac
     3901 agaccaagga taaactagga agccccctag ctcgcccagt tgtggatgga atagtggctg
     3961 ataagttgac ctttttcctt atggaaaatg gggaattagc ttctaacctc atccgcaagg
     4021 ctatcaaggc ccgtgatgct cgtgaagcag cacgtaaggc gcgtgatgag agccgaaatg
     4081 ggaagaaaaa caagaaagat aagggcttgt tgtctgggaa attgacccca gcccaatcta
     4141 agaatcctgc taagaatgaa ctctatctag ttgaggggga ctctgccggt ggttctgcca
     4201 aacaaggtcg tgaccgcaag ttccaggcta ttctacctct tcgtggtaag gttgtcaata
     4261 cagccaaggc caagatggcg gatatcctca aaaatgaaga gatcaatacc atgatttata
     4321 ccattggtgc gggtgttgga gcagacttct ctattgaaga tgccaactat gataagatca
     4381 ttatcatgac cgatgcggat accgacggtg cccatatcca gaccttgctc ttgacatttt
     4441 tctaccgtta catgcgtccg ctagtcgagg caggtcatgt ctatattgcc ctcccacctc
     4501 tttacaagat gtccaaaggt aaaggcaaga aagaagaagt ggcctacgct tggacggacg
     4561 gagaactaga agaactccgt aaacagttcg gtaaaggcgc taccctccaa cgatacaaag
     4621 gacttggtga gatgaatgcg gaccagctct gggaaacaac catgaaccca gaaacacgta
     4681 ccctcatccg tgtcacaatt gaagatttag cgcgcgccga acgccgcgtc aatgttctca
     4741 tgggagataa ggtagaacca cgccgtaaat ggattgaaga taatgtcaag tttacgctag
     4801 aagaagcgac agtgttttaa tgaaagaaaa taatatgtta gtaaactgga aattagagtc
     4861 ggatgtgaat gactatgtga aaaagcagtt tgaaaatctt ggtttgaaaa aattgcagga
     4921 ttattaatga agaatctgct atgagtgctt atctcaaaga ggcgtttaag ggagcggcta
     4981 agacacaaac taagactaat tttggaaaac catattttca tattgaaaaa tacaaacagg
     5041 atagtttggt tacttatcgt aactgaacac gggacgaatt cccgtaaaat atcttttact
     5101 gcataaaaac ctactctaca ttctttgaaa ggagttgaac acgccctaga tactgtgtga
     5161 aaaagataaa ttctcttgtg agtttgctta cttcaagaat tttctatttt cacttggtat
     5221 tttatgggct ttgtatctta tgtctaacat tcaaaacatg tccctggagg acatcatggg
     5281 agagcgcttt ggtcgctact ccaagtacat tattcaagac cgggctttgc cagatattcg
     5341 tgatgggttg aagccggttc agcgccgtat tctttattct atgaataagg atagcaatac
     5401 ttttgacaag agctaccgta agtcggccaa gtcagtcggg aacatcatgg ggaatttcca
     5461 cccacacggg gattcttcta tctatgatgc catggttcgt atgtcacaga actggaaaaa
     5521 tcgtgagatt ctagttgaaa tgcacggtaa taacggttct atggacggag atcctcctgc
     5581 ggctatgcgt tatactgagg cacgtttgtc tgaaattgca ggctaccttc ttcaggatat
     5641 cgagaaaaag acagttcctt ttgcatggaa ctttgacgat acggagaaag aaccaacggt
     5701 cttgccagca gcctttccaa acctcttggt caatggttcg actgggattt cggctggtta
     5761 tgccacagac attcctcccc ataatttagc tgaggtcata gatgctgcag tttacatgat
     5821 tgaccaccca actgcaaaga ttgataaact catggaattc ttgcctggac cagacttccc
     5881 tacaggggct attattcagg gtcgtgatga aatcaagaaa gcttatgaga ctgggaaagg
     5941 gcgcgtggtt gttcgttcca agactgaaat tgaaaagcta aaaggtggta aggaacaaat
     6001 cgttattact gagattcctt atgaaatcaa taaggccaat ctagtcaaga aaatcgatga
     6061 tgttcgtgtt aataacaagg tagctgggat tgctgaggtt cgtgatgagt ctgaccgtga
     6121 tggtcttcgt atcgctatcg aacttaagaa agacgctaat actgagcttg ttctcaacta
     6181 cttatttaag tacaccgacc tacaaatcaa ctacaacttt aatatggtgg cgattgacaa
     6241 tttcacacct cgtcaggttg ggattgttcc aatcctgtct agctacatcg ctcaccgtcg
     6301 agaagtgatt ttggcgcgtt cacgctttga caaagaaaag gctgagaaac gtctccatat
     6361 cgtcgaaggt ttgattcgtg tgatttcgat tttggatgaa gtcattgctc ttatccgtgc
     6421 ttctgagaat aaggcggacg ccaaggaaaa cctcaaagtt agctatgatt ttacggaaga
     6481 acaggctgag gctatcgtaa ctttgcaact gtaccgtttg accaataccg atgtggttgt
     6541 cttgcaggaa gaagaagcag agcttcgtga gaagattgct atgctggtgg ctattatcgg
     6601 tgatgaaagg actatgtaca atctcatgaa gaaagaactt cgtgaggtca agaagaaatt
     6661 tgcaactcct cgtttgagtt ctttagaaga cactgcgaaa gcaattgaga ttgatacagc
     6721 tagtcttatc gctgaggaag atacctacgt cagcgtgacc aaggcaggtt acatcaagcg
     6781 taccagtcca cgttcctttg cggcttccac cttggaagaa attggcaagc gtgatgatga
     6841 ccgtttgatt tttgttcaat ctgccaagac aacccagcac ctcttgatgt tcacaagtct
     6901 tggaaatgtc atctacagac caatccatga gttggcagat attcgttgga aggacatcgg
     6961 agagcatctg agccaaacca tcacaaactt tgaaacgaat gaagcaatcc tttatgtgga
     7021 agtactggat cagtttgacg atgcgacaac ctactttgca gcgactcgcc ttggtcaaat
     7081 caaacgggta gagcgaaaag aattcactcc atggcggacc tatagatcta agtctgtcaa
     7141 gtatgctaag ctcaaagacg atacagatca gattgtagca gtggctccga ttaaactaga
     7201 tgatgttgtc ttggttagtc aaaatggtta tgccctgcgt ttcaatatcg aagaggttcc
     7261 ggttgtcggt gctaaggcag caggtgtcaa ggctatgaat ttgaaagaag atgatgtcct
     7321 ccaatctggc tttatctgta atacttcgtc cttctacctc ttgacccagc gtggaagctt
     7381 gaaacgtgtt tccattgagg aaattctagc aaccagccgt gccaaacgag gattacaagt
     7441 cttgcgtgag ttgaaaaaca aaccgcatcg tgtcttcttg gcaggagcag ttgcagagca
     7501 aggatttgtt ggcgatttct tcagtacgga agtggatgtg aacgaccaaa ctctgcttgt
     7561 ccaatccaat aaaggaacaa tctatgaaag ccgattgcaa gacttgaact tgtcagaacg
     7621 cactagcaat ggaagcttca tttctgacac gatttcagat gaagaagttt ttgacgctta
     7681 tcttcaggaa gtagttactg aagataaata agtgaaatga agaatcagtt ctaagatggt
     7741 ttttattgga gaaattttct gaaaattaca aaatatactt gctattttag aaaaatagtg
     7801 tagaatataa gaaataggtt tttagaataa ggagtggaat atgacagtaa cgattgattg
     7861 ggaaaacctc ggtttttcct atatgaaatt accttatcgc tatcttgctc atttcaaaaa
     7921 tggacaatgg gatcaaggag agcttacaga gtatgcaact ttgcatattt cagagtcttc
     7981 tccaagtctt cactatggac aacaagcatt tgaaggtttg aaagcttatc gtactaagga
     8041 tggcagtgtt caactgttcc gtcctgatga aaatgctaaa cgcctgcaac gtacatgtga
     8101 ccgtctcttg atgccacaag ttccgacaga catgtttgta gaagcttgta aagcagttgt
     8161 ccgtgcgaat gaagaatacg taccaccata cggaataggt ggaactttat atcttcgccc
     8221 tcttttgatt ggtgtcggag atattatcgg ggtaaaaccg gcagaagagt acattttcac
     8281 catctttgct atgccagttg gaaattactt taaaggtggt ttggtcccaa ccaacttctt
     8341 gattcaggat gagtacgacc gtgcagcacc aaatggtaca ggtgcggcta aggttggtgg
     8401 aaactatgct gcaagtctct taccaggaaa aatggccaag tcacgccatt tctcagatgt
     8461 tatctatctg gacccatcaa ctcatacaaa gattgaagaa gtcggatcag ctaatttctt
     8521 tggaattaca gctgataatg aatttgtaac accattgagt ccatctatct tgccatctat
     8581 taccaagtat tccttgcttt atttggcaga acatcgcttg ggattaactc ctattgaggg
     8641 tgatgttcca attgataatc ttgaccgttt tgtagaggca ggtgcctgtg gtacagcagc
     8701 ggttatttct ccaattggag gtattcaaca tggtgatgat ttccatgtat tctatagtga
     8761 aacagaagta ggtcctgtga cgcgtaaatt atataatgaa ttgacgggta ttcagtttgg
     8821 cgatattgaa gcgccagaag gttggattgt aaaagtagat taaaataaac caaaggagat
     8881 tttttatgaa atagaaaaag tggctcttaa cagcaggagt ggtcctgagc acgtcagcta
     8941 ttttagtggc ttgtggaaaa actgataaag aagcagatgc accgacaaca ttttcttatg
     9001 tctatgcagt agatccagca tcattgggct acagtatagc gactcgaaca tcgaggacag
     9061 acgttattgg aaatgttatt gatggtttga tggaaaatga taaatacggc aatgttgctc
     9121 cttctcaaaa agactatgat ttgaacagta caggatgggc tccaagctat caagatccag
     9181 cgtcttactt gaatattatg gatccaaaat ctggttctgc catgaaacac cttggcatta
     9241 cgaaaggaaa agataaggat gttgtagcta aacctggttt ggataaatat aagaaattgt
     9301 tagaagatgc tgtttctgag accactgacc tagagaagag atatgaaaaa tatgccaaag
     9361 ctcaagcttg gtcgacagat agttcattat tgatgccaac agcttcatct ggtggttctc
     9421 cagttgtaag taacgtagta ccattctcaa aaccatactc acaagttggt attaaggggg
     9481 aaccatatat ctttaaagga atgaaattgc aaaaagatat tgttacaaca aaagaatata
     9541 acgaggtttt taaaaaatgg caaaaagaaa aattggaatc caatagcaaa taccaaaaag
     9601 aactagaaaa atacattaaa taaggaatgg tattgatctt gataaaattt ttaaaatact
     9661 gtcattttga atataaagga gtttgatatg gagtggatta gattaatagg aatagcaatc
     9721 attgttgtgg gttttatttt aaaatttgat acaattgcaa cagtagtctt agctggtttg
     9781 gttacagctt tagtttcagg tgtttctctc gttgaatttt tggagatttt gggaaaagaa
     9841 tttagcaatc agcgagtgct cacgattttt atggttacct tgcctcttgt ggggctgtca
     9901 gaaacctttg gactcaagca acgatcaatc gatttgattc gaaagattaa aggtctgaca
     9961 gttggaaact tctatacagt ttatttcttt attcgagagt tagctggttt cttttcaatt
    10021 cgtctaggag gacaccctca gtttgtcaga cctttggttc aacctatggg agaagcagct
    10081 gcagagtctc aattaggtag aaagttaaca gaggttgaag atgagacaat aaaagcgcgt
    10141 gcggctgcga atgaaaattt tggaaatttc tttgctcaaa atacgtttgt aggtgctggg
    10201 ggagtcctct tgataggggg aacattagat cagttaggct atgaaagcaa ttatgcaggg
    10261 attgcttcta catctattat tgttgctgtt ataacactta ttgtagtggg gatttacaat
    10321 tatttatttg ataaaaaatt gatatcaaaa aagactaggg gaggagaaca aaaatgacag
    10381 agttggcaaa gcaactatta gagttgacct atattgtgat tggttgtcaa tttctccata
    10441 cagcctattg tagttataaa gataaaacaa acccagttcg acttgggaca tctgcatttt
    10501 ggactctatt gtctattacg tttataggtg gttcctatat gccaaatatg agtattggta
    10561 ttattgtaat cctattatcg ctgttaacat tgtttaagca agtccgtatc ggaaccttgc
    10621 catccttaga tgaaatgaaa gccaatattg aatctaacag attgaaaaat aaaattttta
    10681 ttccagttat gctgatggca atacttgcgt tggtcttagc gcaaatgatt ccagaattta
    10741 gcaagatttc gattagcctt gccgccttgt ttgctacaat ttctgttctt gtgattacca
    10801 atagtcaccc taagagtctg ttatcagaaa ataatcgaat gactcagcaa gtttcaacaa
    10861 gtgggattgt tcctcaatta ttaggggctt tgggggctat ttttactgta gcaggtgttg
    10921 gtgatgttat ctctcatctg attagcggta ttgttccttc agatagtcgc tttataggag
    10981 ttttggctta tgttcttgga atggttctat tcacaatgat tatgggaaat gcttttgcag
    11041 cattcaccgt tattacagca ggtgttggag ttccctttgt atttgctctg ggagctaatc
    11101 caattgtggc tggtgctctt gccatgacag caggttattg tgggacctta ttgaccccaa
    11161 tggctgctaa ttttaacgct ctaccagcag cattgatgga tatgaaagat cagaatggcg
    11221 ttataaaggc tcaagcaggt gttgctctag taatgattgt tattcacata ttcttaatgt
    11281 actttctcgc attttagtaa aggaaaataa aatgaaaata ttggttacag gttttaatcc
    11341 ttttggaggt gaaaagatta atccagcttt ggaggctgta aaattattac catctgagat
    11401 taatggggct gaagttcgct gggtagaaat tccaacggtt ttttataagt cgtcagaagt
    11461 tttagaggca gaaatattac gatatcaacc agatgctgta ctttgtattg gacaagcagg
    11521 cggcaggacc ggcttaacac ctgaacgagt ggctattaat caagatgatg ctcgcatacc
    11581 tgataacgaa ggcaatcaac caattgatac accgattcgt attgatggag catcggccta
    11641 ttttagtagt ttacctatca aagcgatggt acaagctatc aaaaaacagg gacttccggc
    11701 agttgtatcc aatagtgcag gaacctttgt ttgcaatcat ttgatgtacc aagctcttta
    11761 tttagtggat aaaaaattcc ctaatatgag agcaggtttc atgcatattc catatatgat
    11821 ggaacaagta gtaaataagc cgaatactgc aggaatgagt ctatgtgata ttgtaagagg
    11881 catagaggta gctattgaag ctattgtaga ctacaaagat aaggatttgc agttagtagg
    11941 cggtgagact cactgataac ctaaaaagga tagtcaatta tgcttgttta ctaactatta
    12001 actatgctaa atcaattgag gttgtttaca taaaactcta tatcagagaa gcctgatata
    12061 gagttttttc ttgctagttt taggattttc ttgtaaaata gaaaaagtga agagaggtat
    12121 gaaatgagca agaaagataa aaaaatcgaa attcaagtag cggatgccaa agttaatgtt
    12181 ggtaaagaca gttttgaagg ttatacattg actatcggta aaaaagttat cggagaaatt
    12241 gccgaattag acggacaatt tgccattata aagaatggga atgtcgatag tttttataaa
    12301 aaattggaaa aagctgtgga aattttgatt gaaaattata atttagcaaa ataagtcttg
    12361 tttttttgaa attttcatga tataatagtc catgttgatt gtaggagaga tagcgaagag
    12421 gctaaacgcg gcggactgta aatccgctcc ttcgggttcg ggggttcgaa tccctctctc
    12481 tccatttcat taatggggta tagccaagcg gtaaggcaag ggactttgac tccctcatgc
    12541 gttggttcga atccagctac cccagttctt aggtaataat caagatagaa agcaaaatat
    12601 cttagggtat tttattttta taattgaaag acgtgaatga tatgaacatg tccttgcggg
    12661 tgcttaggaa aaaaattata agtatgtcaa gtttaagaaa aacttgattg ttggaggatt
    12721 ttttagatga acgaatttga agatttgcta aatagcgtta gtcaagttga gactggtgat
    12781 gttgttagtg ctgaagtatt gacagttgat gcgactcaag ctaacgttgc aatctctgga
    12841 actggtgttg aaggtgtctt gactcttcgc gaattgacaa acgatcgtga tgcagatatc
    12901 aatgactttg ttaaagtagg agaagtattg gatgttcttg tacttcgtca agtagttggt
    12961 aaagatactg atacagttac ataccttgta tctaaaaaac gccttgaagc tcgcaaagca
    13021 tgggacaaac ttgttggtcg cgaagaagaa gttgttactg ttaaaggaac gcgtgccgtt
    13081 aaaggtggac tttcagtaga atttgaaggt gttcgtggat ttatcccagc ttcaatgttg
    13141 gatactcgtt tcgtacgtaa cgctgagcgt tttgtaggtc aagaatttga tactaaaatc
    13201 aaagaagtta acgctaaaga aaaccgcttc atcctttcac gtcgtgaagt tgttgaagca
    13261 gctactgcag cagctcgcgc tgaagtattc ggtaaattgg ctgttggtga tgttgtaact
    13321 ggtaaagttg ctcgtatcac aagcttcggc gctttcatcg accttggtgg tgttgacgga
    13381 ttggttcact tgactgaatt gtcacatgaa cgtaacgtat caccaaaatc agttgtaact
    13441 gttggtgaag aaattgaagt gaaaatcctt gatcttaacg aagaagaagg acgtgtatca
    13501 ctttcactta aagcaacagt accaggacca tgggatggcg ttgagcaaaa attggctaaa
    13561 ggtgatgtag tagaaggaac agttaaacgt ttgactgact tcggtgcatt tgttgaagta
    13621 ttgccaggta tcgatggact tgttcacgta tcacaaattt cacacaaacg gattgaaaat
    13681 ccaaaagaag ctcttaaagt tggtcaagaa gttcaagtta aagttcttga agttaacgca
    13741 gatgcagaac gcgtgtcact ttctattaaa gctcttgaag aacgtccagc ccaagaagaa
    13801 ggacaaaaag aagaaaaacg tgctgctcgt ccacgtcgtc caagacgtca agaaaagcgt
    13861 gatttcgaac ttccagaaac acaaacagga ttttcaatgg ctgatttgtt tggtgatatc
    13921 gaactttaat caaattgaaa attcacaaaa tcctttgttt actaaacaag ggatttttct
    13981 ggctctttgt caactgtagt gggttgaagt cagctaagct cgagaaagga caaatttcat
    14041 cctttctttt ttgatattca gagcgataaa aatccgtttt ttgaagtttt caaagttccg
    14101 aaaaccaaag gcattgcgct tgataagttt gatgagatta ttggtcgctt ccagtttggc
    14161 gttagaatag tgtagttgaa gggcgttgat aatcttttct ttatctttga ggaaggtttt
    14221 aaagacagtc tgaaaaatag gatgaacctg cttaagattg tcctcaataa gtccgaaaaa
    14281 tttctctggt tccttattct ggaagtgaaa aagcaagagt tgatagagct gatagtggtg
    14341 tttcaagtct tccgaatagc tcaaaagctt gtttaaaatc tctttattgg ttaagtgcat
    14401 acgaaaagta ggacgataaa atcgcttatc actcagttta cggctatcct gttgtatgag
    14461 cttccagtag cgcttgatag ccttgtattc atggaatttt cgatgaaact gattcatgat
    14521 ttgaacacgc acacgactca tagcacggct aagatgttgt acaatgtgaa ggcgatcaag
    14581 aacgatttta gcattcggga gtgaaacagc ctgggagact gtttcagcct gagcctagaa
    14641 atttgaaagc gaagctgttt agccaagtca tagtaagggc taaacatatc catagtaata
    14701 attttgacgc gacatcggac agctctatcg tagcgaagaa agtgatttcg aatgatagct
    14761 tgtgttcttc cctcaagaac agtgatgata ttgagattgt taaaatcttg cgcaatgaag
    14821 ctcatctcca tctcccgatt gaaacagtca ctccccggac tgtttcaacg tcccaggaca
    14881 taatctcagg aagacgcgaa aaatcatgct caaagtgaga atcattgagc ttgcgaatga
    14941 cagttgaagt tgagatggaa agctgatggg caatatcagt catagaaatc ttttcaatta
    15001 acttttgagc aattttttgg ttgatgatac gagggatttg gtgatttttc tttaccaggg
    15061 gagtctcagc aaccatcatt tttgaacagt gatagcactt gaaacggcgt tttctaagga
    15121 gaattctaga aggcatacca gtcgtttcaa gataaggaat tttagaaggt ttttgaaagt
    15181 catatttctt catttgactt ccgcactcag gacaagatgg agcttcatag tccagtttgg
    15241 cgatgatttc cttgtgtgta tccttattga tgatgtctaa aatctggata ttagggtctt
    15301 taatgtctag taattttgtg ataaaatgta attgttccat atgaatcttt ctaatgagtt
    15361 gtttgatcgc ttttcattat aggtcatatg ggactttttt tctacacaaa aataggctcc
    15421 ataatatcca taggggattt acccactaca aatattatag agcccaaaat cctttgttta
    15481 ctaaacaagg gatttttctt ttgtctctac tccttttttg atataatagt tctatgttaa
    15541 aatcagaaaa acaatcacgt tatcaaatgt taaatgaaga attgtccttc ctattggaag
    15601 gcgaaaccaa tgttttggct aatctttcca acgccagtgc tctcataaaa tcacgttttc
    15661 ctaataccgt atttgcaggc ttttatttgt tcgatggaaa ggaattggtt ttaggcccct
    15721 tccaaggagg tgtttcctgc atccgtattg cactaggcaa gggtgtttgt ggtgaggcag
    15781 ctcactttca ggaaactgtt attgttggag atgtgacgac ctatctcaac tatatttctt
    15841 gtgatagtct agctaaaagt gaaattgtgg tgccgatgat gaagaatggt cagttacttg
    15901 gagttctgga tctggattct tcagagattg aggattacga tgctatggat cgagattatt
    15961 tggaacaatt tgtcgctatt ttgcttgaaa agacagcatg ggactttacg atgtttgagg
    16021 aaaaatctta atgtatcaag cactttatcg aaaatataga agtcaaaact tctcccagtt
    16081 agttggtcaa gaagttgtgg ctaagactct taaacaagcg gtggagcaag agaaaataag
    16141 tcacgcttat cttttttctg gtcctcgtgg aacgggaaaa accagtgttg ctaaaatctt
    16201 tgccaaggct atgaactgtc ccaatcaagt gggtggcgaa ccttgcaata actgctatat
    16261 ttgtcaagca gtgacggacg gtagtttaga agatgtcatt gaaatggatg cagcttctaa
    16321 taatggggta gatgaaattc gcgaaattcg tgataaatct acctatgcgc ctagccttgc
    16381 tcgttataag gtttatatca tagatgaggt tcacatgctg tctacagggg cttttaatgc
    16441 cctcctaaag acgctggaag aaccaacaca gaatgtagtc tttattttgg ccactactga
    16501 attgcacaag attcctgcta ctattctatc ccgtgtgcaa cgttttgagt ttaaatcaat
    16561 taagacacag gatattaagg aacatattca ctatatctta gaaaaagaaa atatcagttc
    16621 tgaaccagag gctgtggaaa tcattgccag acgggcggaa ggtggaatgc gggacgcctt
    16681 gtctattttg gatcaagccc tgagtttgac acagggaaat gagctgacga ctgctatctc
    16741 tgaagaaatt actggcacca ttagcctatc agccttggat gattatgtgg cggccttgtc
    16801 tcaacaggat gttcccaaag ctttgtcttg cttgaatctt ctttttgaca atggtaagag
    16861 catgactcgt tttgtgaccg atcttttgca ctatttaaga gacttgttaa ttgttcaaac
    16921 agggggagaa aatactcatc atagttcagt ctttgtagaa aatttggcac ttcctcaaaa
    16981 aaatctgttt gaaatgattc gcttagcaac agtgaattta gcagatatta agtctagttt
    17041 gcagcccaag atttatgctg aaatgatgac cgtccgtttg gcggaaatca agcccgaacc
    17101 agctctatca ggagcggttg aaaatgaaat tgctacgctg agacaggaag ttgcccgtct
    17161 caaacaagag ctttctaatg caggtgcggt tcctaaacaa gttgcaccag ctcctagtcg
    17221 accagctacg ggcaaaacag tctatcgtgt cgatcgcaat aaagtgcaat ctatcttaca
    17281 agaggccgtc gaaaatcctg atttagcacg tcaaaatcta attcgtttgc agaatgcctg
    17341 gggagaggta attgaaagtc taggtgggcc ggacaaggct ctgctagttg gttctcaacc
    17401 ggttgctgcc aatgaacacc atgctattct tgcttttgag tctaacttca atgctggtca
    17461 aactatgaaa cgagacaatc tcaataccat gtttggtaat atcctcagtc aggcggcagg
    17521 tttttcacct gagattttag ctatttccat ggaggaatgg aaagaagttc gcgcagcctt
    17581 ttcagccaaa gccaaatctt ctcaaactga aaaagaagta gaagaaagcc tgattccaga
    17641 aggatttgaa tttttggctg ataaagtgaa ggtagaggaa gactaaagaa agatttcatg
    17701 atacaataag tttatgaata aacaacaatt tattattatg gcgctattta cagctgctga
    17761 gacctatttt ttcaatgaag cctggatgac tggccgctat attatggcag ccttttgggc
    17821 aattttactc tttagaaatt tccgagtcag ttatgtgatg ggtaaaattg ttgatgtcat
    17881 cgatcagcat tttaatagga aagactagcc ctcagcttcc agacaaaatc aaagcctttt
    17941 aggctttttt ttgttatact agaaaagtat atttatagaa tttttgctct atttctgggg
    18001 aaatcagacg tttttctagt aagtactgta aaagttttga aaaagaaagg aactatcatg
    18061 tcagtaatag agatcaaaga tcttcacgtt gagattgaag gaaaagaaat tttaaaaggg
    18121 gttaacctga ccctgaaaac aggagaaatt gccgctatca tgggaccaaa tggtacaggt
    18181 aaatcgactc tttctgccgc tatcatggga aatccaaact atgaagtaac taaaggtgaa
    18241 gttttgtttg atggcgtaaa catccttgag ttggaagtgg atgagcgtgc gcgtatggga
    18301 cttttccttg ctatgcaata cccatcagaa atccctggaa ttaccaatgc tgagtttctt
    18361 cgtgccgcta tgaatgcggg taaagaagat gatgagaaga tttcagttcg tgagtttatt
    18421 actaagctag atgaaaaaat ggaattgctc aacatgaaag aagaaatggc agagcgttac
    18481 ctcaacgaag gcttctctgg tggtgagaaa aaacgcaatg aaattcttca acttttgatg
    18541 ttggagccaa catttgctct tttggacgag attgactcag gtcttgatat tgacgctctt
    18601 aaagttgtgt ctaaaggtgt caatgccatg cgtggtgaag gttttggtgc tatgatcatc
    18661 actcactacc aacgtctttt gaactatatc acacctgatg tggtacacgt gatgatggaa
    18721 ggtcgtgttg tcctttctgg tggtccagaa ttggctgcgc gtttggaacg tgaaggatac
    18781 gcaaaactag ctgaagaact tggctacgac tacaaggaag aattgtaatt ccctcgtatc
    18841 ttttaggaga agtaaatgac tagagaaaat attaaacttt tttcagaaat gcacgctgaa
    18901 ccaagctggt tggctgatct ccgtcaaaaa gcttttgaca agattgagac tttggaatta
    18961 ccagttattg agcgtgtcaa attccaccgt tggaatctgg gtgatggaac gattacagaa
    19021 aatgagccat cagcaaatgt tccagatttc acagctttag atcatcactt gaagttggtg
    19081 caagtaggaa ctcaaactgt tttcgaacaa actccagttg agttagctga acagggtgtt
    19141 gtcttcacag actttcactc agctttagaa gaaattccag agctgatcga agaattcttc
    19201 atgtcatctg ttaagtatga tgatgacaag ttggcggctt accacacagc ttactttaac
    19261 agtggtgctg tactctatat tccagataac gtagaaatca cagagccaat tgaaggaatt
    19321 ttctaccaag atagcgatag caatgtgccg tttaacaagc atattatgat tatcgctggt
    19381 aaaaattcta agattagtta tctggagcgt ttagagtcac gcggtgaagg aagtgacaaa
    19441 gtaactgcca atatcacagt ggaagtgatt gcacgttctg gtgcgcaagt caagtttgct
    19501 gctatcgacc gtctaggtga aaacgtcact gcctacatta gccgtcgtgg taaattaggc
    19561 aacgatgcaa gtattgactg ggctatcggt gtcatgaacg aaggaaatgt cgttgctgat
    19621 tttgatagtg acttgattgg taatggtagc catgctgacc tcaaggttgt agctctttca
    19681 agtggtcgtc aggtacaagg gattgatact cgtgtaacta actatggctg caactctatc
    19741 ggaaatatcc tacaacatgg ggttatcctt gaaaaagcaa ctttgacttt caatggtatc
    19801 ggccacatca tcaagggtgc taagggagca gatgcgcaac aagagagccg tgttctcatg
    19861 ctttcagacc aagcgcgttc agatgctaac ccaattcttt tgattgatga aaatgatgtc
    19921 actgcaggac acgcagcgtc tatcggacaa gttgatccag aagacatgta ttacctcatg
    19981 agtcgtggat tggataaggc aactgcagag cgtttggttg ttcgtggttt ccttggatct
    20041 gttatcgtgg agattccagt caaggaagtt cgtgatgaaa tgattgcaac tatcgaagag
    20101 aaattgtcaa aacgctaagg ggaagcctat gttagatgta gaagcgattc gcaaggattt
    20161 tccaatttta gatcagattg tcaatgatga acctctggtc tatctggaca atgctgcgac
    20221 gacacaaaaa ccactagtag ttctgaaagc tattaacagt tactatgagc aggacaatgc
    20281 caatgttcac cgtggtgtcc ataccttagc ggaacgagcg acagcttctt atgaagctgc
    20341 tcgtgaaacc attcgtaagt ttattaatgc aggctctaca aaggaagttc tctttaccag
    20401 aggaacgaca accagcctta actgggtggc acgctttgct gaggaaattc tcgctgaggg
    20461 agaccgggtc ttgatttcag taatggaaca ccattctaat atcattccat ggcaggaagc
    20521 ttgtcgaaag actggagcag agcttgtcta tgtctatctt aaagacggtg ccttggatat
    20581 ggaggatttg cgagctaaat tgactgataa ggttaaattt gtttccctag ctcatgcctc
    20641 caatgttctt ggtgtggtca atccgatcaa ggaaatcact caattagccc accaagttgg
    20701 ggcaattatg gtagtggatg gtgctcaatc tacacctcat atgaagattg atgtccagga
    20761 cttggatctg gactttttcg ccttttcggg tcacaagatg gctggtccga ctggtatcgg
    20821 tgtcctttac ggcaaagaaa agtatcttga gcaaatgtct ccagtagaat ttggcggcga
    20881 gatgattgat tttgtctacg agcaatttgc tagttggaag gaattgcctt ggaaatttga
    20941 ggctggaacg ccaaatatgg caggagctat tggacttgcg actgcagttg attatctgga
    21001 aaagattggt atggatgccg ttgaagctca tgaacaggaa ttgattgcgt acgtctatcc
    21061 aaaactgcag gcaattgagg gattgaccat ttacggttct caggatttgg ctcaacgttc
    21121 gggtgttatt gcctttaacc taggtgatct ccatcctcac gatcttgcga cggctctgga
    21181 ttatgaagga gtggctgttc gtgctggtca ccattgtgcg caacccttgc ttcagtattt
    21241 ggaagtccca gcaacagctc gtgcaagttt ttatatctac aataccaagg cagattgcga
    21301 caaactagtc gatgccctac aaaagacaaa ggagtttttc aatggcactt tctaaactag
    21361 atagccttta tatggcagtg gtagcagacc attcgaaaaa tccacatcac caagggaagt
    21421 tagaagatgc tgagcaaacc agtctcaaca atccgacttg tggggatgtc atcaacctct
    21481 ctgtcaagtt tgatgcagag gaccgtttgg aagatattgc ttttctaaat tcaggatgca
    21541 cgatttcaac tgcttctgct agtatgatga cagatgccgt tttaggaaaa accaaacaag
    21601 aaattttaga actggcgact attttttctg aaatggttca agggcaaaaa gatgagcgtc
    21661 aaggccaact tggagacgcg gcattcttgt caggtgttgc caaattccct caaagaatca
    21721 agtgtgcaac cctagcttgg aatgccctta agaaaacaat tgaaaatcaa gaaaaacagt
    21781 aagacaagtt tcttttgtct tatgaattat tagaaatgaa gaaagaaagg atactatggc
    21841 tgaagaaaga gtagaaccaa aaccaattga ccttggtgaa tataaatttg gtttccatga
    21901 cgatgtagag cctgtcttat cgacaggaaa aggactcaac gaaggtgtta ttcgtgaatt
    21961 atctgctgct aagggtgagc ctgagtggat gttggagttc cgtttgaagt cttatgaaac
    22021 cttcaaaaaa atgcccatgc aaacttgggg agcagacttg tcagagattg actttgatga
    22081 cttaatctac taccaaaaac catctgacaa accagcccgt tcttgggatg atgtacctga
    22141 aaagattaaa gaaacctttg aacgtatcgg gattccagaa gctgaacgtg cttatttagc
    22201 aggggcttct gcccagtacg agtcagaagt ggtttaccac aacatgaagg aagagttcca
    22261 aaaattaggt attatcttta cagatacaga ttccgcactc aaggaatacc cagacttatt
    22321 taaacaatac tttgcgaagt tggtaccgcc gacagataac aagttggcag ccctcaactc
    22381 agcagtatgg tcgggtggaa cttttatcta cgtgccaaaa ggtgtcaagg tagatattcc
    22441 acttcaaact tatttccgta tcaataacga aaatataggt cagttcgaac gtaccttgat
    22501 tatcgttgat gagggagcaa gcgtccacta cgtagaagga tgtacagcac caacatattc
    22561 aagcaatagc ttacacgctg ccattgtaga aatttttgct ttggacggag cttatatgcg
    22621 ttatacaact atccaaaact ggtctgataa cgtctataac ttggtaacaa agcgtgctaa
    22681 ggctcaaaag gatgccactg ttgagtggat tgatggaaac ttgggtgcca aaacgactat
    22741 gaaatatcca tctgtttacc ttgatggaga aggagcgcgt ggtaccatgc tctctatcgc
    22801 ctttgctaat gcagggcaac accaagacac gggtgctaag atgattcaca atgctccaca
    22861 taccagctcg tctattgtgt ctaaatccat cgctaaaggt ggaggaaagg ttgactaccg
    22921 tggacaagtc acctttaaca agaactctaa gaaatctgtt tcccacattg aatgtgatac
    22981 cattatcatg gatgacttgt cagcatcaga tactattcca tttaatgaaa ttcacaactc
    23041 gcaagtggct ttggaacacg aagccaaagt atctaagatt tcagaagagc aattgtatta
    23101 tctcatgagc cgtggattgt cagaatctga ggcaactgaa atgattgtca tgggatttgt
    23161 agaacccttt acaaaagaac ttccaatgga atacgcagtt gagctgaacc gcttgattag
    23221 ctatgaaatg gagggatcag ttggataaaa tttgatttta tactcttcga aaatctcttc
    23281 aagccacgtc agcatcgcct taccgtatgt atggttactg acttcgtcag tttcatctac
    23341 aacctcaaaa cagtgttttg agcaacctgc ggctagcttc ctagtttgtt ctttgatttt
    23401 gagtattaga tttactcaaa atcaaggatt ttgaagatga acttgtatca aaaaatcgcg
    23461 gtttaaaatc gcgatttttt ataatttctc gttaacaaag cggacaaact gattccacca
    23521 aacttttaag aagaaggctt tttcaatttt cttgtctgct accatttcga aactagggcg
    23581 ctctgtggtg atgtaacctt gaccaatcaa gtccttgtct tcataagtca aatggccaac
    23641 cactgttcta gcttcaagtg gtgctgggat tgctttggaa tcaggtgtga attgaacaga
    23701 ttgggaagat tgattcccaa tctgttcgat tagatagata tcctctggag ccactgcagt
    23761 tactgtatct tcttttccat cttgtacagg ggctttgcta tcttgatagg catcgccttg
    23821 ttgaacgatt ttgcgaagtg taaatgtaga agaaatataa tccattaggg aagatgtagc
    23881 tgtaaatcga gcgtaaggat tattgtcttg atgatctgca tttaaaacaa ctgtgatgac
    23941 tctcatgcct ttttcgacag tagtaccaac aaaagactct ccagccttat ctgttgttcc
    24001 tgtttttagc ccatcaaaac caccacggta agcaggcata ccttctaaca tgtagttggt
    24061 tgaagtgatt gtcatcccag caaaagtaga agaaggtttt ttggtgattt ctaagacttg
    24121 tgggtatttt ttgatgaggt tgcgagcaac gatagcgaca tcataagcac taagcttatt
    24181 ttcctcatct tttttagaac ctgggtaaat gttatcccct agagtttcat tgttaagacc
    24241 tgtcgtattg acaacagtgg catcctgaat tccccattcc aagagttttg cccgcatcat
    24301 atcgacgaaa tctttttctg agccagcaat tttctcagct agggcaatag cggcgctgtt
    24361 ggcactagat accagagttg cttcaagcaa ctcttcgaca gtataattac gggcctccat
    24421 aggaatatta ctggcttcag aatttgtcgt caattgataa ggataatcag aaatatctac
    24481 aggagtggag agggtaatac ttccgttttc caaagcttca tagaccagat aaacagtaat
    24541 caattttgtt atggaagcaa tttcgacagg ttgcgttgca tccttctcat agagaatttt
    24601 accagtattt gcctcaacag caatcgcatg tttagcggca atggtaaaat cttgagcaac
    24661 agcagtagaa gcacccccta aaagagagac agttaacaaa gttaaaaata tttttttcat
    24721 agtagtctta ttctatcata aagaaaaaaa atattcttgc tttaataatt catctgttaa
    24781 gctttttgaa aatatggtaa aataaagtga gggaggtaac tcatgtttcg tagaaataaa
    24841 ttattttttt ggaccacaga aattttactc ttaaccatca tcttttacct atggagacag
    24901 atggggtctt tgattaaccc ttttgttagc gtgcttaata caattatgat tccattttta
    24961 ttagggggct ttctttatta tttgacaaac cctattgtta ctttcttaaa taaagtctgt
    25021 aaactcaatc gtttgcttgg tattttaatt accttgtgta ctttggtctg gggaatggtc
    25081 ataggtgttg tctatctctt acctattttg attaatcagt tatctagttt gattatatct
    25141 agtcaaacta tttatagtcg agtacaagac ttaatcatag acttatctaa ttatcctgcg
    25201 ctccagaatt tggatgtaga agctacaatt cagcagttaa acttatccta tgttgatatt
    25261 cttcaaaata tcctaaatag cgtatcaaat agtgtgggga gcgtcttgtc agctcttatc
    25321 agtactgttt tgattttgat tatgactcca gtttttttgg tttatttctt attagatgga
    25381 cataaattct tgcccatgct tgaaagaacg attctaaaga gggatcgctt gcatattgca
    25441 ggcttattaa agaatttaaa tgcgacgatt gctcgctata ttagtggagt ttcgattgac
    25501 gcaatcatta taggttgttt agcttatatt ggctatagta ttattggttt aaaatatgct
    25561 ttagtttttg ccattttttc tggtgtagcc aatttaattc cttatgtggg gccaagtatt
    25621 ggtttgattc ctatgatcat cgcaaatata ttcactgatc cccatagact gctgattgca
    25681 gtgatttata tgcttgttgt tcagcaggta gatggcaata tcttatatcc tcgaatcgta
    25741 ggaagtgtta tgaaggttca tccaatcacg attttagttt tacttttgtt gtcaagcaat
    25801 atttatggtg tagttggaat gattgtcgca gtgccaacct attctatctt gaaagaaatt
    25861 tctaagttct tatcccgttt gtatgaaaat cataaaataa tgaaagaacg agaaagagaa
    25921 ttagctaagt aaaagtcagg agaaccctga tttttcttta ctggaagtgg cctttagatt
    25981 agaagactga aaataagtta aagtcttaaa ctaattttca cagctaagaa tagtagaagt
    26041 taatctgata aaaatcgaaa aaaccagtgg aattccgtgt cagggtaagt tccactggtt
    26101 ttcatagtct attaaagttc gaatgaaacc tatttatagt atattgaaac tagaatagta
    26161 cacctcta
//
LOCUS       DAVKMO010000024        25935 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVKMO010000024 DAVKMO010000000
VERSION     DAVKMO010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25935
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.024"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            363..1526
                     /locus_tag="VW361_001169"
     CDS             363..1526
                     /locus_tag="VW361_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU9744212.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            1523..2200
                     /locus_tag="VW361_001170"
     CDS             1523..2200
                     /locus_tag="VW361_001170"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU9744213.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            2190..3044
                     /locus_tag="VW361_001171"
     CDS             2190..3044
                     /locus_tag="VW361_001171"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU9744214.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQFSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            3063..4130
                     /locus_tag="VW361_001172"
     CDS             3063..4130
                     /locus_tag="VW361_001172"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU9744215.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     IAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            4140..5306
                     /gene="aroC"
                     /locus_tag="VW361_001173"
     CDS             4140..5306
                     /gene="aroC"
                     /locus_tag="VW361_001173"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU9744216.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIENDQVVFTSGVRHGKTTGAPITMYVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            5316..6419
                     /locus_tag="VW361_001174"
     CDS             5316..6419
                     /locus_tag="VW361_001174"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU9744217.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEAIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            6430..6768
                     /locus_tag="VW361_001175"
     CDS             6430..6768
                     /locus_tag="VW361_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU9744218.1"
                     /translation="MSNIYDSANDLSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            6860..8143
                     /gene="aroA"
                     /locus_tag="VW361_001176"
     CDS             6860..8143
                     /gene="aroA"
                     /locus_tag="VW361_001176"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU9744219.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITVQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEICGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            8136..8612
                     /locus_tag="VW361_001177"
     CDS             8136..8612
                     /locus_tag="VW361_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU9744220.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQRDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            8609..9457
                     /gene="pheA"
                     /locus_tag="VW361_001178"
     CDS             8609..9457
                     /gene="pheA"
                     /locus_tag="VW361_001178"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9744221.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAIAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWLLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            9454..10728
                     /gene="psr"
                     /locus_tag="VW361_001179"
     CDS             9454..10728
                     /gene="psr"
                     /locus_tag="VW361_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU9744222.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFVYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            11007..11852
                     /locus_tag="VW361_001180"
     CDS             11007..11852
                     /locus_tag="VW361_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9744223.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKNFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            11842..12945
                     /locus_tag="VW361_001181"
     CDS             11842..12945
                     /locus_tag="VW361_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9744224.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            12947..13933
                     /locus_tag="VW361_001182"
     CDS             12947..13933
                     /locus_tag="VW361_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9744225.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            13949..15382
                     /locus_tag="VW361_001183"
     CDS             13949..15382
                     /locus_tag="VW361_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU9744226.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMI
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            15411..16445
                     /locus_tag="VW361_001184"
     CDS             15411..16445
                     /locus_tag="VW361_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9744227.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            16645..17382
                     /gene="mecA"
                     /locus_tag="VW361_001185"
     CDS             16645..17382
                     /gene="mecA"
                     /locus_tag="VW361_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU9744228.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            17533..18819
                     /locus_tag="VW361_001186"
     CDS             17533..18819
                     /locus_tag="VW361_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU9744229.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVAFYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            18821..19690
                     /locus_tag="VW361_001187"
     CDS             18821..19690
                     /locus_tag="VW361_001187"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU9744230.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            19940..20878
                     /gene="msrB"
                     /locus_tag="VW361_001188"
     CDS             19940..20878
                     /gene="msrB"
                     /locus_tag="VW361_001188"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9744231.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            20936..22660
                     /locus_tag="VW361_001189"
     CDS             20936..22660
                     /locus_tag="VW361_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744232.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLIPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVKLFKGTIRSNLTLGLNQEVSDQKLWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            22662..24410
                     /locus_tag="VW361_001190"
     CDS             22662..24410
                     /locus_tag="VW361_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744233.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRASLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQFPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            24667..25926
                     /locus_tag="VW361_001191"
     CDS             24667..25926
                     /locus_tag="VW361_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU9744234.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIELLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVVVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLIVEL"
BASE COUNT         7637 a         4859 c         5856 g         7583 t
ORIGIN      
        1 gtttgtaaca aaaggcttct ctataaaatc aaattttcca gatacctatt gaagtagatt
       61 tatttcttca tctttcttct actacctttg tcactaaatt tgacagacac atattgctga
      121 ttcaacctct ctacctataa tctcacagtt aacctgaggc tagtttcata gtttgctatt
      181 tgattttcgt tgataaaaag aaatgctcct ccaagacgga agagcatttt ttattgtgat
      241 tcttacacat ttacttccta gttttgcagg aagtctagta taccattttt taaaagaaga
      301 gtaaaaaagc aagggtagtt tcttttttga gaattgtcta aaagtttgat ataatggtag
      361 ttatgaatag aataagagtc agcaaaaggg ttgaaaagaa gcttgctaag gggctagttt
      421 tactagaagc cagtgatctt gagaatgtca atcttaagga tcaggaagta gaggtgcagg
      481 gtcaggaagg aaactttctt gggactgcct acctttctca gcaaaacaag ggcttgggct
      541 ggtttgtcag caaagacaag gtggccttca atcaaacttt ctttgaaacg ttgtttagaa
      601 aagccaaaga aaagagaaac gcctactatc aagatgattt gacaactgcc tttcgtctct
      661 ttaatcaaga gggagatggc tttgggggtc tgacagtgga cctttatggc gactacgccg
      721 tcttttcttg gtataactct tatgtttatc agattcgtca gactatatca gaagccttta
      781 gacaggtttt ccctgaggtt ttaggggctt atgagaaaat ccgctttaag ggttttgact
      841 atgaatctgc ccatgtttat ggtcaagaag cacctgactt tttcactgtt ttagaaaatg
      901 gtgtcctgta tcaagtcttt atgaatgatg gcttgatgac aggaattttc ctagaccagc
      961 atgaggttcg cggtagttta gttgacggct tggctatggg taaatccttg ctcaatatgt
     1021 tttcctacac agcggctttt tcagtagctg cggccatggg aggagctagc cagacaactt
     1081 ctgttgatct agccaaacgt tcacgagaat tgtctcaagc gcattttcag gcaaatgggc
     1141 tcagcacaga cgagcatcgt tttatagtca tggatgtctt tgagtatttc aaatatgcca
     1201 aacgcaaaga cttgacctac gatgtgattg tcctagatcc gcctagcttt gctcggaata
     1261 aaaaacaaac tttctctgtg gccaaggatt atcacaagtt gatttcccag agtcttgaga
     1321 ttttaaatcc gggagggatt atcattgcca gtactaatgc tgccaatgtt tcccgtcaga
     1381 aatttacaga acaaattgat aaaggctttg caggaagaag ttaccagatt ttaaacaaat
     1441 atggtcttcc agcagatttt gcctataata aaaaagatga aagtagtaat tacctcaagg
     1501 tgattagtat gaaggttagt aaatgaaatt aatcgtttca gtaatgccaa gaagtttaga
     1561 ggaggctcag gctctggatg ccacgaggta cctggatgcc gacatcattg aatggcgtgc
     1621 cgactatctg cctaaagaag cgattttgca ggtagctcca gccatttttg aaaaattcgc
     1681 aggccgtgag ttggttttca cgctacgaac tcgctccgaa ggtggagaaa tcgacctttc
     1741 tccagaagag tatatccatc taatcaagga agttgcgcaa ttctatcaac cagactatat
     1801 tgattttgag tactatagct acaaggatgt ttttgaggaa atgctggact tcccaaatct
     1861 tgttttgagt taccataatt tccaagaaac acctgagaac atgatggaaa tcttgtcaga
     1921 gttgacgatc ctaaatccaa aacttgttaa ggttgcggtg atggctcaca cggagcagga
     1981 tgtcttagac ttgatgaact atacacgagg ctttaaaacc ctcaatcctg aacaggaata
     2041 tgtgaccatt tctatgggta aggtgggcaa ggtctctcgt atcactgcgg atgtgactgg
     2101 ttcgagttgg tcttttgcca gtctggatga ggttagtgcc cctgggcaga tttctctagc
     2161 tagcatgaaa aaaatcaggg agattttgga tgaagcttga tggctataca cgtttagctg
     2221 cagttgttgc caatcctatt aagcattcta tttctccctt catccacaat agagcctttg
     2281 aggcgacagc taccaacggt gcttatgtgg cttgggagat tgaagcgagt gacttggtag
     2341 aaacagtggc caatattcgt cgctaccaga tgtttggcat caatctgtcc atgccctata
     2401 aggagcaggt gattccttat ttggataagc tgagcgatga agcgcgcttg attggtgcgg
     2461 ttaatacggt tgtcaatgag aatggcaatt taattggata taatacagat ggcaagggat
     2521 tttttaagtg cttgccttct tttacaattt caggtaaaaa gatgaccctg ctgggtgcag
     2581 gtggtgcggc taaatcaatc ttggcacagg ctattttgga tggcgtcagt cagatttcgg
     2641 tctttgttcg ttccgtttct atggaaaaaa caagacctta cctagacaag ttacaggagc
     2701 agacaggctt taaagtggat ttgtgtgctt tagaatatgt ttctgaactg caagcaagga
     2761 ttgccgagtc ggatttgcta gttaatgcca ccagtgtggg catggatggc caattctctc
     2821 ctgttcctga aaacatagtc ttaccagaaa ctctcttagt tgcagatatc atataccaac
     2881 cctttgaaac accgtttttg aaatgggcta gaagtcaggg caatccagca gtcaatggtc
     2941 tgggaatgtt gctctatcaa gctgcagaag cttttcaact gtggacaggc aaggaaatgc
     3001 cgacagaaga gatttggcag tctttaacag aaaaatacca ataaagaaag ggagactctc
     3061 ctatgaaaat cagaatcgat attcctcatc atccttatga tattcagatt gaaaaaggtt
     3121 gtatggccca ggctggtcag tggttgcgag aactctggca accgcaaaag gtagtcattg
     3181 tgacagataa ccatgtagcc tctctctatg cagagaaggt caagctcagc ctagaagatg
     3241 ctggttttca ggtagctgtt tttgatttct tagaaggtga agaaagaaag aatttaacta
     3301 ctgttcagaa agtctatgaa tttctagtca agcaaggtct gactcgtagc gatggaatcg
     3361 ttgctcttgg tggtggcgtt gttggggacc tggctggatt tgtagcctct acctatatgc
     3421 ggggtattca ctttgttcag attccgacta gtttgacagc tcaggttgat tcttctatcg
     3481 gtggaaagac aggtgttaac acaccatttg ctaaaaatat ggtggggacc tttgcccaac
     3541 cagatggggt tttgattgat ccacttgttc ttgaaaccct cggaaaaaga gagttgattg
     3601 aagggatggg tgaagttatc aagtatggct tgattgagga tccagaactg tgggctctct
     3661 tgacgggact gaatggttct gttgagagta ttttggaaca tgcagagacc ttgattgaac
     3721 attcttgtca ggtgaagcgc aagatggtgg ttgaagatga gttggacaat ggtattcgtc
     3781 tttacctcaa ttttggccac actattggcc atgccatcga agcgactgcc ggttatggca
     3841 aggtcatgca tggagaggct gttgccatgg gaatggtaca gatttccaag attgctgagg
     3901 aaaaaggcct catgccagct ggcattaccc aatctatcac agagatgtgt cagaaattcg
     3961 gcttgcctgt tgactatgaa aattgggaag ttgacaagct ttatcaggct cttactcatg
     4021 acaagaaagc gcgtggcaac accttgaaat tggtcttggt gccagagctt ggttcagcga
     4081 ccattcatcc agtttctctg gaagagatga aagactactt ggtaaaataa ggagagtgta
     4141 tgagatattt aactgcagga gaatcacacg gcccccgtct aacagctatt attgagggaa
     4201 ttccagctgg acttccattg acagctgagg atatcaatga ggaccttaga cgccgtcagg
     4261 gtggctacgg tcgtggtggt cgtatgaaga ttgagaatga ccaggttgtc tttacttcgg
     4321 gcgttcgcca cgggaagacg acaggggcgc ctattactat gtatgtcatc aataaggacc
     4381 accagaaatg gctggacatc atgtctgcgg aggacattga agaccgcctt aaaagcaagc
     4441 ggaaaattac tcatcctcgc ccaggtcatg ccgatttggt tggggggatt aagtaccgtt
     4501 ttgatgattt gcgaaattct ttggagcgtt catcagctcg tgaaaccacc atgcgggtgg
     4561 cagttggtgc agtagccaaa cgtctcttgg ctgagctgga tatggagatt gccaaccatg
     4621 tcgtggtctt tggtggcaag gaaatcgatg ttcctgaaaa tctgacagtc gctgaaatta
     4681 agcaaagagc tgcccagtct gaagtttcta ttgtcaacca agaacgagaa caggaaatca
     4741 aggactatat tgaccaaatc aaacgtgatg gtgataccat cggtggggtt gtggagacag
     4801 tcgtcggagg cgttccagtt ggtcttggtt cctatgtcca atgggataga aaattggatg
     4861 caagattggc tcaagctgtt gtctctatca atgcctttaa aggggtggaa tttggtcttg
     4921 gctttgaggc tggttatcgt aaaggcagcc aagttatgga tgaaattctc tggtctaaag
     4981 aagacggtta tactcgccgt accaataatc taggtggttt tgaaggtggt atgactaatg
     5041 ggcaacccat cgttgttcgt ggggtcatga aacccattcc tactctttat aaacctctta
     5101 tgagtgtgga tatcgaaacc cacgaacctt acaaggcaac cgtggagaga agtgatccga
     5161 ctgctcttcc agctgcagga atggtcatgg aagcagttgt agcaacggtt ctggcgcaag
     5221 aaatcctcga aaaattctca tcagataatc ttgaggaact aaaagaagcg gtagccaaac
     5281 accgagacta tacaaagaac tattaaggag ttcctatggc aaaaacaatc tatatcgcag
     5341 gtcttgggtt gattggagcc tctatggcac ttggtatcaa acgcgatcat ccagattatg
     5401 aaattttagg ttataatcgt agtcaagctt cgagagatat cgccttgaaa gaaggcatga
     5461 ttgaccgtgc aacggatgat tttgctagtt ttgctccttt ggcagatgtc attatcctca
     5521 gcttgccaat caaacaaact attgctttca ttaaggagtt ggccaatttg gatttgcgag
     5581 aaggcgttat tatttcagat gctggttcga ccaagtcaac cattgtggat gcggcggagc
     5641 agtatttggc tggcaagtct gttcgctttg tcggggccca tcccatggct ggtagtcaca
     5701 agacaggggc tgcttcggca gatgtcaatc tttttgaaaa tgcctattat atctttacac
     5761 cttcaagcct gacaagtcag gacacgctta aggaaatgaa ggatctgctt tcaggtcttc
     5821 atgctcgttt tatcgagatt gatgccaagg agcatgatcg tgtcacttct cagattagcc
     5881 attttcctca tattttggct tctagtctca tggagcagac tgcggtctat gctcaagagc
     5941 atgagatggc aaggcgcttt gcggcaggtg gttttcgaga tatgacccga attgcggaaa
     6001 gcgagccagg aatgtggacc tccattctct tgtccaatag cgagaccatt ctggatagaa
     6061 ttgaggattt caaggaacgt ttggaagcga ttggtcaggc cattagtaag ggagatgaag
     6121 agcaaatttg gaactttttt aaccaagcgc gtgaacaacg ccagaccatg gaaatccata
     6181 agcgtggtgg tgtggatagc tcttacgacc tctatgttga cgttcctgat gaagaagatg
     6241 tcatcctgcg gattttggaa ctgctacgtg ggacttcctt ggttaacatc cacatcaacg
     6301 aggaaaatcg tgaggatatt cacggaatcc tacaaatttc atttaaaaat gctcaagact
     6361 tggaaagagc cgagcatctc ataacaaaaa ataccgacta tacagtcgtc attaaataag
     6421 gagaagaaca tgtcaaatat ttacgatagt gcaaacgacc tcagtcgcgg tctacgcgga
     6481 ttaccagaat acaaggctgt taaagcagct aaagatgcga ttgcagcaga tgctgaggca
     6541 agcaaaatct ttacagaata tcttgccttt caagaggaaa ttcaaaaact agcacagaca
     6601 ggtcaaatgc cagatgcgtc cttccaagct aagatggaag gctttggtaa acagattcaa
     6661 ggaaatagcc tcttgtcaga attctttacc aagcaacaac aattggccat ttacctttct
     6721 gacattgaaa aaattgtttt cgaaccagtt tcagaattgc tgaaataaga aaagaactat
     6781 cctaaagtca ggaattttta aggaatttct ggctttttat gataaaatag gtaaaagtat
     6841 tgcaagtatg aggtccagta tgaaactaaa aacaaacatt cgccatttac atggtagtat
     6901 ccgcgtccca ggtgacaagt ctatcagcca ccgttccatt atctttggaa gtttggctga
     6961 gggtgagacc aaggtttatg atattctgcg aggtgaagac gttctttcga ccatgcaggt
     7021 ttttcgtgac cttggtgttg aaattgagga taaagatggg gttattaccg ttcaaggtgt
     7081 aggcatggct ggcttaaaag cgccgcaaaa tgcccttaat atgggaaatt ctggcacctc
     7141 gattcgcctg atttcaggtg tccttgctgg tgcagatttc gaagtagaga tgtttggaga
     7201 tgatagtctt tccaaacgtc ctatggaccg tgtgaccctt ccactgaaaa aaatgggcgt
     7261 cagcatctca gggcaaactg aacgagactt gcctcccctt cgcttaaaag ggacgaaaaa
     7321 cctaagacct attcattatg agttgccaat tgcctctgcc caagtcaagt cagccttgat
     7381 gtttgcagcc ttacaagcta agggggagtc agttattatc gaaaaagagt acacccgtaa
     7441 tcatactgaa gatatgttgc aacaatttgg tggtcattta agtgtggatg gtaagaaaat
     7501 cacagtccaa gggccacaaa aattgacagg acagaaggtg gtcgtaccag gagatatttc
     7561 cagtgcagcc ttttggttag tcgcaggttt gattgctcca aattctcgtc tagtgctgca
     7621 gaatgtgggg ataaacgaaa ctcgcaccgg tattattgat gtcattcgtg ccatgggtgg
     7681 aaaattggaa ataactgaaa tcgatccagt cgctaaatct gcaaccttga ttgttgagtc
     7741 ttctgacttg aaaggaacag agatttgtgg cgctttgatt ccacgtttga ttgatgaatt
     7801 gcctattatt gccctacttg cgacccaagc ccaaggtgta acagttatca aggatgctga
     7861 ggagctcaag gtcaaggaaa cagaccgtat tcaggttgtg gcagacgcct taaatagtat
     7921 gggagcagat attactccta cggcagatgg gatgattatc aaaggaaaat cagctcttca
     7981 cggtgctaga gtcaatacgt ttggtgacca ccgtatcggc atgatgacag ctatcgcagc
     8041 cctattggtt gcagatggag aggtggagct tgaccgtgca gaagccatca ataccagcta
     8101 tcctagtttc tttgatgatt tggagagctt gattcatggc taaggtgtta ttagggttta
     8161 tgggggctgg aaaatcgact attgcaagag gcttggaccc taattacctt gatatggatg
     8221 ctctgattga gaagcgccta ggtatgtcca ttgcgaattt tttcgctgaa aagggagaag
     8281 cagcctttcg tcaggtagaa tcagaagtcc tagctgattt attacaaaga gaccaagtcg
     8341 tgtcaactgg aggaggagtg gttatttctc agagaaatcg tgacttactc aagactaata
     8401 cagataacat ctacctgaaa gcagattttg aaaccctcta cctacgtatc gcagctgata
     8461 aggacaatca gcgaccgctt tttctaaata atagcaagga agaactagta gctatttttc
     8521 aagaaagaca ggcttggtat gaggaagtgg ctagtcgggt tttggatgtg accaagctaa
     8581 gcccagagga aattatagag gaactaagat gaaaattgct tatctaggtc ccaaaggatc
     8641 attttcacac cacgttgtgc agacagcttt tcctcatgag gaattgcagg cttttgccaa
     8701 cattacagat gtcatcaagg cttatgagca aggattagtg gactattctg tggtgccagt
     8761 tgaaaattct attgagggta gtgttcatga aaccttggac tatctttttc atcaggctca
     8821 catccaagca gtagcagaaa tcgttcagcc tattcatcag cagttgatgg tggttccagg
     8881 ccatactaag attgaaaaga ttttttcaca tccacaggcc ttggctcaag gaaagaaatt
     8941 catcgatgaa caatatccag aggctcaaat cgaggtaaca gctagtacag cttatgcggc
     9001 ccgttttatt tccgaacatc cagatcagcc ctttgcagca attgcaccta gaagttctgc
     9061 tgaagaatat ggattggaac tgattgccga ggatattcag gaaatggaag ccaatttcac
     9121 acgtttctgg cttctaggag ctgaaaagcc tagtattccc ttgcaagcac aaactgaaaa
     9181 gatgagtttg gccttgacat tacctgacaa ccttccaggt gcactttata aggccctgtc
     9241 gacctttgct tggcgaggaa ttgacttgac aaaaattgaa agtcgtccac tcaagacagc
     9301 actgggtgaa tactttttca ttatcgatgt ggattatacc gataaggact tggtccactt
     9361 tgcccaaaaa gaattagaag cgattggaat ccagtataaa attctgggtg cctatcctat
     9421 ttatccaata tcagaccatg gaaaggagag aagatgagta aagaaaatcc cttaagtcat
     9481 catgagcagt tgcgttatga ttatttgcta aaaaatattc actatctcaa tgagagagaa
     9541 aaaaatgagt ttgtctattt gcaagaaaag ctaactcttg ctaggggaaa tagtagctct
     9601 agcttggaac aagaaagaga agagcaggtt gacttaccaa gctatgcgaa ccggagtcgc
     9661 tcacaatcca aatcacaagc actctctttc cctccaaaaa agaaaagacg gaagctccgt
     9721 cttaaacgaa tttttatggt gattttttca cttttggtct gtgtggcttt ggccatggta
     9781 ttcatgtttt tgcgtggtta ccaagatgct agcgcaaaga aaactgctga tgcccgggca
     9841 gctcaagtag aagtctttaa tggtcaggac actagagatg gagttaatat tttaatcatg
     9901 ggtactgatg gtcgaatcgg ccagaacagt gttgagacac gaactgactc tattatggta
     9961 ttaaatgtcg ggggctcaga taagaaaatg aagctagtca gtttcatgcg tgataatttg
    10021 gtctatatag atggttatag tcaagtgatt aacggtagaa aacagacaga taacaagtta
    10081 aacgtagcct acgagttagg agaacaagag gggcaaaaag gggcagaaat ggttcgccaa
    10141 gtcttgaaag ataattttga cttggacatt aagtactacg ccttggttga tttccaggcc
    10201 tttgccacag cgattgacac gcttttccct gatggggtga cgattgatgc tcaattttca
    10261 acattgaatg ggcgtcccct aacagaagct acagtcggag atgatttata cgctaccgag
    10321 actgagtctc caacccaaac cattaaagtc ggaaaacagc agatgaatgg ctcgaccctg
    10381 ctcaattatg ctcgtttccg tgatgatgat gaggcggatt acggccgtac aaaaagacag
    10441 caacaagttt taacagcaat tttagagcaa attaaagatc ccactaaact tttcactggt
    10501 tctgaagctc ttggaaaggt ttttgctatg acctcaacca acgtacccta tactttcctc
    10561 ctaacaaacg gtttatctgt tttggatgga gcaaaaaatg gtattgaaaa attgacgatt
    10621 ccagaactgg gtgactgggt agatgcctat gatgtttatg gaggcttggg cttgctggtt
    10681 gatcaaaaca aatatcaaac caagctcgct caaatgggct tgagataaga taatactcaa
    10741 tgaaaatcaa agtgcaaatt aggaagctag ccgcaggctg ctaaaaacac agttttgagg
    10801 ttgtagataa gactgacgaa gtcagttacc tatacctacg gcaaggtgaa gctgacgttg
    10861 tttgaagaga ttttcgaaga gtataagaca gaaaaatcaa agtttgatag ctatttggat
    10921 agcagtcagg ctttgatttt ttacagtctg caatagattt tcaccccttg tttgtggtat
    10981 aatgaaacga tacgatagaa agaataatga ataatatgac tgatttaaaa gcaattcagg
    11041 ctcgtagtct ggagatggct gaatattttg tggccttttg taaagaacat gatttgctct
    11101 gttatctctg tggcggaggc gctattggtg cccttcgaaa caagggattt attccttggg
    11161 acgacgacct agactttttt atgcctcgta aagattatga gaaattagca gaattatggc
    11221 ctcgttatgc agatgaacgt tatttcttgt caaagagtca caagaatttt gttgatcgta
    11281 atctttttat taccattcgt gacaaggaaa ccacctgtat caagccttat cagcaggatt
    11341 tggatttgcc acatggtctg gccttggatg ttttgccttt ggattattat ccgaaaaatc
    11401 cagctgagcg gaaaaaacag gttcgttggg ccttgattta ttcactcttt tgtgcgcaaa
    11461 ctattccaga aaagcatggt gctctcatga aatggggaag tcgcatttta ctgggtttga
    11521 ctccaaaatc tctccgttat cgcatctgga aaaaagctga gaaagaaatg actaagtatg
    11581 atttggctga ttgtgatggc attacagaat tatgctcagg tcctggctac atgagaaaca
    11641 agtacccaat cacatctttt gaagacaatc ttttcttgcc atttgaagga acagagatgc
    11701 ctattccaat cggctatgat gtctatctca gaactgcttt tggggattat atgacgcctc
    11761 caccagcaga caagcaggta ccgcatcatg atgctgtcat cgctgatatg gataagtctt
    11821 atacagaata caagggagaa tatggtggct aagaaaaaaa tcttattttt tatgtggtct
    11881 ttttctcttg gaggtggtgc agagaagatt ctatcaacca ttgtttcaaa tctggatcca
    11941 gaaaagtatg atattgatat tcttgaaatg gagcactttg acaagggata tgaatctgtt
    12001 ccaaagcatg tacgcatttt aaaatccctt caagattatc gccaaaccag atggttacga
    12061 gcttttttgt ggagaatgag aatttatttt ccaagactga ctcgtcgttt gcttgtaaaa
    12121 gatgattatg atgttgaagt ttcttttacc attatgaatc caccactgtt gttctctaaa
    12181 agaagagaag tcaagaagat atcttggatt catggaagta ttgaagaact tcttaaggat
    12241 agctctaaaa gagaatcaca tagaagccag ttggatgctg cgaatacaat tgtagggatt
    12301 tcaaaaaaga ccagcaattc tatcaaggaa gtttatccag attatgcttc taaattacag
    12361 acaatctaca atggatatga ttttcagact attctagaaa aatctcaaga gaagatcgat
    12421 atcgagattg ctcctcaaag tatctgtact atcggacgga ttgaggaaaa taagggttct
    12481 gaccgtgtag tggaagtgat acgattatta caccaagagg gaaaaaacta tcatctctat
    12541 tttatcgggg ctggtgatat ggaagaggaa ctgaaaaaac gagtcaaaga gtatgagatt
    12601 gaggactatg tacatttcct tggttatcaa aaaaatcctt atcagtattt atctcagacg
    12661 aaagttctct tgtctatgtc taaacaagaa ggctttcctg gagtgtatgt ggaggccttg
    12721 agtctgggac tcccttttat ctctacggac gttggagggg ctgaggaatt atcccaagaa
    12781 ggacgatttg gacaaatcat tgagagcaat caagaggcag ctcaggcgat tactaattac
    12841 atgacttctg cctcaaactt taatgtcgat gaggctagcc aattcattca acaatttaca
    12901 attacaaaac aaatcgaaca agtagaaaaa ctattagagg agtagcatgg aaactgcatt
    12961 aattagtgtg attgtgccag tctataatgt ggcgcagtac ctagaaaaat cgatagcttc
    13021 cattcagaag cagacctatc aaaatctgga aattattctt gttgatgatg gtgcaacaga
    13081 tgaaagtggt cgcttgtgtg attcaatcgc tgaacaagat gacagggtgt cagtgcttca
    13141 taaaaagaac gaaggattgt cgcaagcacg aaatgatggg atgaagcagg ctcacgggga
    13201 ttatctgatt tttattgact cagatgatta tatccatcca gaaatgattc agagcttata
    13261 tgagcaatta gttcaagaag atgcggatgt ttcaagctgt ggtgtcatga atgtctatgc
    13321 taatgatgaa agcccacagt cagccaatca ggatgactat tttgtctgtg attctcaaac
    13381 atttctaaag gaatacctca taggtgaaaa aatacctggg acgatttgca ataagctaat
    13441 caagagacaa attgcaactg ccctatcctt tcctaagggg ttgatttacg aagatgccta
    13501 ttaccatttt gatttaatca agttggccaa gaagtatgtg gttaatacta aaccctatta
    13561 ttactatttc catagagggg atagtattac gaccaaaccc tatgcaaaga aggatttagc
    13621 ctatattgat atctaccaaa agttttataa tgaagttgtg aaaaactatc ctgacttgaa
    13681 agaggtcgct tttttcagat tggcctatgc tcacttcttt attctggata agatgttgct
    13741 agatgatcag tataaacagt ttgaagccta ttctcagatt catcgttttt taaaaggcta
    13801 tgcttttgct atttctagga atccaatttt ccgtaagggg agaagaatta gtgctttggc
    13861 cctattcata aatatttcct tataccgatt cttattactg aaaaatattg aaaaatctaa
    13921 aaaattacat tagaacgggg gtgaccaagt gattgatggg aaacgattat tatttagttt
    13981 gaccatagtc agttatacct tgacgctagt aagtggaatt gtgtatctgt ttaataataa
    14041 taatgttagc ttactttcta ctttattgtt cttgttggtt agtagcttaa ttgcttgttg
    14101 gaatgatatc aagtattact taatccattt tattttctat ttaaccattt ttgtatttct
    14161 ggtatcaaga ccgaccattg attattttag ggatggtgct ttggatacct atcatccaat
    14221 agcctatcgt tttgccttta tagttgtcat gatttcgatt ctgggcttga ccacaggagg
    14281 cgtcctggct cgttacttca tagctaggaa gaaaataaaa gtagcaaata taggaaattc
    14341 tctaaaagag gtttatatca agcggttacg ctttgtatca ctaggagttt ttcttctaac
    14401 ctatcctttc tatttcattc ggttatttga acggctcttg tatcgtttgc agacttccta
    14461 ctatgcctac tatgcaaatt ttgaaagtaa actgccttat tttacctaca ttttgtctac
    14521 ctttacggtc tatgcaatgt gtatgtatct ggcaaccaag ccaaagaaat tgcaggccac
    14581 agcagtgctt gtctccttta ttgcagctaa tactattcat ttggcaattg ggacacgaaa
    14641 tccctttatt ttaagtattt tatttgcttt tgtttattac tttatgcggg agcaaactga
    14701 aaaaggaaaa tggattgggt ttaaagaaaa gttagcgatt tttgtaggtt ctcctattct
    14761 catgttagcg atgggagtac ttaattatgt acgggataat gtccaagttt cccatacagg
    14821 tttctgggat atcttacttg actttatcta taaacaagga actagttttg gtgttctggc
    14881 tcgaggtttt ctatttaaca gtagcctccc ttaccgagat ttccgtaatt ttacttttgg
    14941 tcctgttctt gattattttg caagggggag tttgggagcc attttcggag gaaaagcctt
    15001 tgaacataca accaatagtg tggaactagc tattgatagt aatagttatg cccacaatct
    15061 atcctatctt gtcttgaaca aggaatactt gaaagggcat ggtatcggaa gtagttatat
    15121 catggagttg tataccgact atggtatgat tggagtcttt ctgcttagtt tcttactcgg
    15181 cgtattattt atagccatgc tgcaagtagc ctatcgctca aggacaatcc tatttgcttt
    15241 atccctactc atcttgaata atctattctt tatgccaaga agcagctttt cagaaagttt
    15301 cttcaattta tttacaatgc aattctgggg aattgttctt gtgattatat ttgtagcaaa
    15361 aatgcttaca aaggaaaact agtatctact aaacaaagga gaaaaaaatc atgtttgaac
    15421 attattcagt agctgatttg tttgcaaatc tttataaaaa acgaaaagca aatattttag
    15481 ctctcatcgc tttatttgct ctcattgctg taccatttac aattaaagca gttaggaata
    15541 aaaacactgt caaagataca acaagttatt caacttatct tatctataaa atcactcctc
    15601 cagaagattc ggccaaaacg attttgaatc atcaaattgg tggttatagt gatttttatg
    15661 ggaaattgat tgatggtaat ttgaatggag cttatctttt caatgatgta gaacccagtg
    15721 agttgaaaaa aattgccagt gaattagaca cgacggaaac aaccttgaaa aattcaacga
    15781 atgactattg gtggaaaaaa ttgaccgtct actatatgat tgacgatgca ggggttggtg
    15841 tgaaaatttt gacatcaagt aaagatgcca atgacttgtt agagaaaaaa attgatgggt
    15901 tgattgagaa atttaaacat gcttatgcaa atgtgaaaat tgaaaaactg gaaaccatca
    15961 actctaaaga attgaacgca aatggtgaaa cagcgcttgg cttaaatgtg aaaaatctga
    16021 ttcttcgttt agttgttatt ggagtggttt gtgtgatttt ggttgtgatg ggaaatgtgt
    16081 tagtttatct ctttaatcca acaatcaata gagtaggtga tttttctcag tatcaaattg
    16141 attttgtaac agagattaca acaattgcta acctagcaga tgttttgtca tacaaaaata
    16201 ctggacagga attgaccatc gttagctcaa ataaagctat cctagataaa ttgaaacaga
    16261 gtcaagaagc tttaaaagga atgcattttg tagatttgca ggatgtatca tctcttttgg
    16321 aaagagatac agtccttctt gttgaagagt acggagtgac tcgttataag aaatttgagc
    16381 aaagtcttca aattctcaga aacttaaatc gttctatcct cggtgtagca acctttaaat
    16441 tataagtatt ctgatgtata aggtcttcaa aatcggctaa gagccgattt tgaaggcttt
    16501 ttctatctgt ctgcagaaat tttctcttgg agtctcctat agaaagaccc tagggaaaat
    16561 ctatccgtat agaggagcct tcttttgata aaatcgtaaa aatctagtat aatagataga
    16621 actgaaagta tgaggttact agcaatgaaa atgaaacaaa ttagtgatac aactttaaaa
    16681 atcacgatgt ctttagagga tttgatggat cgtggaatgg agattgctga ctttctcgtt
    16741 cctcaagaaa aaacagaaga gttcttttat gctatcttgg atgagctaga gatgcctgat
    16801 agctttctgg atacaggcat gttgagcttc cgtgtgactc caaaacctga taaggtagat
    16861 gtctttgtga ccaagtcaaa gattgaccaa aatctagatt ttgaagactt atcggatttg
    16921 ccagatatgg aagaattggc tcaaatgtct ccagatgaat ttatcaaaac cctggaaaaa
    16981 agcatcgcag acaaaaccaa ggatgatatc gaagccattc aatctcttga gcaagttgaa
    17041 gccaaggaag aagagcaaga gcaggctgaa caagaagctg agagtaagaa agaaccttac
    17101 atctactaca tcctttcttt tgctaagttg gctgacttgg tagcttttgc caagacagtg
    17161 acttttgaaa tggaaacttc tgaactctac aaaatgaacg agcgctatta tttgaccatt
    17221 ttagtggata ttgaaaatca tccaagccca tatccagctt ggctgttggc ccgtatgcgc
    17281 gagtttgcag acgatagtga tatcagtcgc tcagtcttac aagagtatgg tcaagtcttg
    17341 atgagtcacg atgcagtgct caatctgcaa aaaatcggct aatcctttct ggaaagctat
    17401 tttcagattt taagaagagc gaatcgtctg attcgttttt tctttttata ctgaaatagt
    17461 gatttactat aataggaatt ttcacaaaat tctgttataa tggctatatt agaaaatttc
    17521 gaggagataa agatgacagt taaaattgct ttactaggat ttggtaccgt tgcaagtggt
    17581 gtgcctttcc tcctaaagga aaatggagga aaaatcaatc aatcagcaca ttcagatatc
    17641 aaagttgcta aggtattggt caaggatgaa gatgaaaaaa atcgcttgct tgcagcaggg
    17701 aatgacttta actttgtaac caatgtggat gatattttat cagaccagga tattactatc
    17761 gtagtggaat tgatggggcg tattgagcct gctaaaacct ttatcactcg tgccttggaa
    17821 gctggaaaac acgttgttac tgctaacaag gaccttttag ctgtccatgg cgcagaattg
    17881 ctagaaatcg ctcaagctaa caaggtagca ttttactacg aagcagcagt tgctggtggg
    17941 attccaattc ttcgtacttt agcaaattcc ttggcttctg ataaaattac gcgcgtgctt
    18001 ggagtagtca acggaacttc caacttcatg gtgaccaaga tggtggaaga aggctggtct
    18061 tacgatgatg ctcttgcgga agcacaacgt ctaggatttg cagaaagcga tccgacgaat
    18121 gacgtagatg ggattgatgc agcctacaag atggttattt tgagccaatt tgcctttggc
    18181 atgaagattg cctttgatga tgtagcccac aagggaatac gcaatatcac accagaagac
    18241 gtagctgtag ctcaagagct tggttacgta gtgaaattgg ttggttctat tgaggaaact
    18301 tcttcaggta ttgctgcaga agtgactcca accttcctac ctaaagcgca cccacttgct
    18361 agtgtgaatg gcgtaatgaa cgctgtcttt gtagaatcta tcggtattgg tgagtctatg
    18421 tactacggac caggtgcggg tcaaaaacca actgcaacaa gtgttgtagc tgatattgtc
    18481 cgtatcgttc gtcgtttgaa tgatggtacc attggcaaag acttcaacga atatagccgt
    18541 gacttggtct tggcaaatcc tgaagatgtc aaagcaaact actatttctc aatcttggct
    18601 ccagactcaa aaggtcaggt cttgaagttg gctgaaatct tcaatgctca agatatttcc
    18661 tttaagcaaa tccttcaaga tggcaaagag ggtgacaagg cgcgtgtcgt tatcatcaca
    18721 cacaagatta ataaagccca gcttgaaaat gtctcagctg aattgaagaa ggtttcagaa
    18781 ttcgacctct tgaatacctt caaggtgcta ggagaataag atgaagatta ttgtacctgc
    18841 aaccagtgcc aatatcgggc caggttttga ctcggtcggt gtagctgtaa ccaagtatct
    18901 tcaaattgag gtctgcgaag aacgagatga gtggctgatt gaacaccaga ttggcaaatg
    18961 gattccacat gatgagcgta atctcttgct caaaatcgct ttgcaaattg taccagactt
    19021 gcaaccaaga cgcttgaaaa tgaccagtga tgtccctttg gcgcgcggtt tgggttcttc
    19081 cagctcggtt atcgttgctg ggattgaact agccaaccaa ctgggtcaac tcaacttatc
    19141 agaccatgaa aaattgcagt tagcgaccaa gattgaaggg catcctgaca atgtggctcc
    19201 agccatttat ggtaatctcg ttattgcaag ttctgttgaa gggcaagtct ctgctatcgt
    19261 agcagacttt ccagagtgtg attttctagc ttacattcca aactatgaat tacgtactcg
    19321 cgacagccgt agtgtcttgc ctaaaaaatt gtcttataag gaagctgttg ctgcaagttc
    19381 tatcgccaat gtagcggttg ctgccttgtt ggcaggagac atggtgaccg ctgggcaagc
    19441 aatcgaggga gatctcttcc atgagcgcta tcgtcaggac ttggtaagag aatttgcgat
    19501 gattaagcaa gtgaccaaag aaaatggggc ctatgcaacc tacctttctg gtgctgggcc
    19561 gacagttatg gttctggctt ctcatgacaa gatgccaaca attaaggcag aattggaaaa
    19621 gcaacctttc aaaggaaaac tgcatgactt gagagttgat acccaaggtg tccgtgtaga
    19681 agcaaaataa agaatagaag ataggatggg gaaactcttg accagagggt ttcatatcct
    19741 ttttgtgaaa agaagtttat actcaatgaa aatcaaagag caaactagga agctagccgc
    19801 aggctgctca aaacagtgtt ttgaggttgt ggatagaact gacgaagtca gtaacatata
    19861 tacggtaagg tgacgctgac gtggtttgaa gagattttcg aagagtatta gttaaaaacg
    19921 tgataaagga gaaataaaga tggcagaaat ttatctagca ggtggttgtt tttggggcct
    19981 agaggaatat ttttcacgca tttctggagt gctagaaacc agtgttggct acgctaatgg
    20041 tcaagtcgaa acgaccaatt accagttgat caaggaaaca gaccatgcag aaacggtcca
    20101 agtgatttac gatgagaagg aagtgtcact cagagagatt ttactttatt atttccgagt
    20161 tatcgatcct ctatctatca atcaacaagg gaatgaccgt ggtcgccaat atcgaactgg
    20221 gatttattat caggatgaag cagatttgcc agctatctac acagtggtac aggagcagga
    20281 acgcatgctg ggtcgaaaga ttgcagtaga agtggagcaa ttacgccact acattctggc
    20341 tgaagactac caccaagatt atctcaggaa gaatccttca ggttactgtc atatcgatgt
    20401 gaccgatgct gataagccat tgattgatgc agcaaactat gaaaagccta gtcaagaggt
    20461 gttgaaggcc agtctatctg aagagtctta tcgtgtcaca caagaagctg ctacagaggc
    20521 tccatttacc aatgcctatg accaaacctt tgaagagggg atttatgtag atattacgac
    20581 aggtgagcca ctcttttttg ccaaggataa gtttgcttca ggttgtggtt ggccaagttt
    20641 tagccgtccg atttccaaag agttgattca ttattacaag gatctgagcc atggaatgga
    20701 gcgaattgaa gttcgttctc gttcaggcag tgctcacttg ggtcatgttt tcacagatgg
    20761 accgcgggag ttaggcggcc tccgttactg tatcaattct gcttctttac gctttgtggc
    20821 caaggatgag atggaaaaag caggatatgg ctatctattg ccttacttaa acaaataaaa
    20881 cagagagtgg ggcttcccac tttcttcatt tctagaatat gaatagaagg gatttatgaa
    20941 acacctatta tcttacttca aaccctacat caaggaatca attttagccc ccttgttcaa
    21001 gctgttagaa gctgtttttg agctcttggt tcccatggtg attgctggga ttgttgacca
    21061 atctttacct cagggagatc aaggtcatct ctggatgcag attggcctgc tccttatctt
    21121 tgcagtaatt ggcgttttag tggccttgat agctcaattt tactcagcaa aggcagcagt
    21181 aggttttgct aaggaattga caaacgatct ttatcgtcat attctttcct tgcccaagga
    21241 cagcagagac cgtctgacaa cttctagttt ggttactcgc ttgacttcgg atacctacca
    21301 gattcagact ggtatcaatc aattcctgcg tctcttttta cgagcgccca ttatcgtttt
    21361 tggtgccatt tttatggctt atcgaatctc agctgagttg actttctggt tcttagtcat
    21421 ggttgccatt ttgaccattg tcattgtagg gttatctcga ttggtcaatc ctctctacag
    21481 tagtctcaga aagaaaacgg accaactggt tcaggaaacg cgccagcaat tgcaagggat
    21541 gcgggttatt cgtgcttttg gtcaagaaaa acgagagtta cagatttttc aaacccttaa
    21601 ccaagtttat gctagattac aagaaaagac aggtttcttg tctagtttat taatacctct
    21661 gacctatctg attgtcaatg gaactcttct cgttattatc tggcaaggct atatttcaat
    21721 tcaaggagga gtactcagtc aaggtgctct cattgctctt atcaattacc tcttacagat
    21781 tttggtggaa ttggtcaagc tagccatgct gatcaattcc ctcaaccagt cctatatctc
    21841 agccaagaga atcgaggagg tctttgcgga atctcccgaa aacatccatt cagaattaga
    21901 acaaaagcaa gttaccagtg gtcgggtttt acaagtccaa gaattgactt ttacctatcc
    21961 tgatgcggcc cagccttctc tgagagacat ttcctttgat atgactcaag gacaaatcct
    22021 tggtatcatt ggggggactg gttctggtaa atcaagcttg gtgcaactct tacttggact
    22081 ttatccagta gacaagggga acattgacct ttatcaaaat ggacgtagtc ctcttaattt
    22141 ggagcagtgg cggtcttgga ttgcctatgt acctcaaaag gtcaaactct ttaagggaac
    22201 tattcgttcc aacttgactt taggtttaaa tcaagaagta tctgaccaga aactctggca
    22261 ggccttggag attgcgcaag ctaaggattt tgtcagtgaa aaggaaggac ttttggatgc
    22321 cctagttgag gcaggggggc gaaatttctc aggtggacaa aaacaaaggt tgtctatcgc
    22381 ccgagcagtc ttgcgccaag ctccgtttat catcctagat gatgcaacct cggcactgga
    22441 taccattaca gagtccaagc tcttgaaagc tattagagaa aattttccaa acacgagctt
    22501 aattttgatc tctcaacgaa cctcaacttt acagatggcg gaccagattc tcctcttgga
    22561 aaaaggtgag ttgctagctg ttggcaagca cgatgacttg atgaaatcca gccaagtcta
    22621 tcgtgaaatc aatgcatccc aacatggaaa ggaggactag aatgaaacga caaactgtaa
    22681 accagacgct caaacgttta gccgtagatt tagcaaacca tcccttcctc cttttcctag
    22741 cctttctagg aactattgcc caagttggct tatcaattta cctacctatt ctgattgggc
    22801 aggtcattga ccaagtccta gtggctggtt catcaccagt tttttggcag atttttctcc
    22861 agatgctctt ggtggtaata ggaaatactc tggtacaatg ggccaatcct ctcctctata
    22921 atcgtctaat cttctcttat accagagatt tgcgagagcg aatcatccat aagctccatc
    22981 gtttaccgat tgcttttgta gataggcaag gtagtggaga gatggttagt cgtgtaacca
    23041 cggacatcga acagttggca gctggcttga ccatgatttt taaccaattt ttcattggtg
    23101 ttttgatgat tctggttagt attctagcca tgctccaaat tcatctcctc atgactctct
    23161 tagtcttgct gttgacgcca ctgtccatgg tgatttcacg ctttattgcc aagagatcct
    23221 atcatctctt ccagaagcaa acagagacga ggggaattca gactcagttg attgaagaat
    23281 cgcttagcca gcagactata atccagtcct tcaatgctca aacagaattt atccaaagat
    23341 tgcgtgaggc tcatgacaac tactcaggct attctcagtc agccatcttt tattcttcaa
    23401 cggtcaatcc ttcgactcgc tttgtaaatg cactcattta tgccctttta gctggagtag
    23461 gagcttatcg tatcatgatg ggttcaacct tgaccgtcgg tcgtttagtg acttttttga
    23521 actatgttca gcaatacacc aagcccttta atgatatttc ttcagtgcta gctgagttgc
    23581 aaagtgctct ggcttgcgta gagcgtatct atggagtctt agatagccct gaagtggctg
    23641 aaacaggtaa ggaagtcttg accagtgacc aagttaaggg agctatttcc tttaaacatg
    23701 tctcttttgg ctaccatcct gaaaaaattt tgattaagga cttgtctatc gatattccag
    23761 ctggtagtaa gatagccatc gttggtccga caggtgctgg aaaatcaact cttatcaatc
    23821 tccttatgcg tttttatccc attagctcgg gagatatctt gctggatggg caatccattt
    23881 atgattatac acgagcatca ttgagacagc agtttggtat ggtgcttcaa gaaacctggc
    23941 tcacacaagg gaccattcat gataatattg cctttggcaa tcctgaagcc agtcgagagc
    24001 aagtaattgc tgctgccaaa gcagctaatg cagacttttt catccaacag tttccacagg
    24061 gatacgatac caagttggaa aatgctggag aatctctctc tgtcggccaa gctcagctct
    24121 tgaccatagc ccgagtcttt ctggctattc caaagattct tatcttagac gaggcaactt
    24181 cttccattga tacacggaca gaagtgctgg tacaggatgc ctttgcaaaa ctcatgaagg
    24241 gccgcacaag cttcatcatt gctcaccgtt tgtcaaccat tcaggatgcg gatttaattc
    24301 ttgtcttagt agatggtgat attgttgaat atggtaacca tcaagaactc atggatagaa
    24361 agggtaagta ttaccaaatg caaaaagctg cggcttttag ttctgaataa gccattctct
    24421 tttgaaagtt tatggacgaa aaaagttgcc ttcgagtgac ttttttgtta caatagctag
    24481 aaaaattgtt cactgtaata ctcaatgaaa atcaaagagc aaactaggaa gctagccgta
    24541 ggttgctcaa aacagtgttt tgaggttgca gatagaactg acgaagtcag taaccacacc
    24601 tacggcaaag tgaatttgaa gtggtttgaa gagagtacaa cttgtctttt agaaaaggag
    24661 cctataatga aagtctttca gcatgtaaat atcgtgactt gtgatcaaga tttccatgtt
    24721 tatcttgatg gaatcttagc agtcaaggat tctcaaatcg tctatgtcgg tcaagataag
    24781 ccagcgtttt tagaacaagc tgagcagatt atagactatc agggagcttg gattatgcct
    24841 ggtttggtca attgtcacac ccattctgca atgacaggtc tgagagggat ccgagatgac
    24901 agcaatctcc atgaatggct caatgactat atctggccag cagaatctga gtttactccc
    24961 gacatgacta ccaatgcggt caaagaagcc ctaacagaga tgctccagtc aggaacaaca
    25021 acctttaacg atatgtataa tcccaatggt gtggatatcc agcaaattta tcaggtggtg
    25081 aaaacttcca agatgcgttg ttatttttct ccgactctct tttcttcaga gacagaaaca
    25141 actgctgaga ctataagcag aactcgatcc atcatagacg aaatcttaaa atataaaaat
    25201 ccaaatttca aggttatggt agcacctcat tctccgtata gctgcagtag agacttgctg
    25261 gaagcgagtt tggaaatggc aaaagagcta aatattccgc tccatgtcca tgtggcggag
    25321 accaaggagg agtcaggaat tatcctcaaa cggtacggca aacgccccct tgcttttctt
    25381 gaagaactgg gttatttaga tcatccgtcc gtatttgctc acggggtcga attaaacgag
    25441 agagaaattg aactcttggc atcttctcaa gtggctatcg cccacaatcc tatcagtaac
    25501 ctcaaactgg catcaggaat tgctccaatt atccagctcc aaaaagcggg agtagtagtc
    25561 ggaattgcga ctgactcggt tgcttccaat aacaatctag atatgtttga ggaaggaagg
    25621 actgcagctc ttcttcagaa gatgaaaagt ggggatgcca gccagtttcc aatcgaaaca
    25681 gctctcaagg tactgacaat cgaaggggct aaggtccttg gaatggaaaa tcagatagga
    25741 agtctggaag tcggcaagca agcagatttt ctggtcattc aaccacaagg gaaaattcat
    25801 ctccaacctc aggaaaatat gctgtctcac ctggtttatg cagttaaatc tagtgatgta
    25861 gatgatgttt atatcgccgg agaacaggtt gttaagcaag gtcaagtcct gatagtagaa
    25921 ctttaaaaga aaaat
//
LOCUS       DAVKMO010000025        25278 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVKMO010000025 DAVKMO010000000
VERSION     DAVKMO010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.025"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            187..1164
                     /locus_tag="VW361_001192"
     CDS             187..1164
                     /locus_tag="VW361_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9744235.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETATTFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQTHHT
                     MTEEVAAFAHMIQQPDLNLYQTWLDDAGSVHELLYTMRQTAGIRFEAEK"
     gene            1161..2243
                     /locus_tag="VW361_001193"
     CDS             1161..2243
                     /locus_tag="VW361_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9744236.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFDPLLTGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKNGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2307..3356)
                     /locus_tag="VW361_001194"
                     /pseudo
     CDS             complement(2307..3356)
                     /locus_tag="VW361_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(3740..4936)
                     /gene="tuf"
                     /locus_tag="VW361_001195"
     CDS             complement(3740..4936)
                     /gene="tuf"
                     /locus_tag="VW361_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9744237.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(5847..6716)
                     /locus_tag="VW361_001196"
     CDS             complement(5847..6716)
                     /locus_tag="VW361_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9744238.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYTATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(6939..7460)
                     /locus_tag="VW361_001197"
     CDS             complement(6939..7460)
                     /locus_tag="VW361_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9744239.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAG
                     LGLGFFKKKEDEK"
     gene            complement(7418..8524)
                     /locus_tag="VW361_001198"
     CDS             complement(7418..8524)
                     /locus_tag="VW361_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU9744240.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVRVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(8635..8889)
                     /locus_tag="VW361_001199"
     CDS             complement(8635..8889)
                     /locus_tag="VW361_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744241.1"
                     /translation="MLNVDQDFMSISKSNKSDSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(9229..9762)
                     /locus_tag="VW361_001200"
     CDS             complement(9229..9762)
                     /locus_tag="VW361_001200"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEU9744242.1"
                     /translation="MTSFKEQESEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVGGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLERFFKTR"
     gene            complement(9749..9964)
                     /locus_tag="VW361_001201"
     CDS             complement(9749..9964)
                     /locus_tag="VW361_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9744243.1"
                     /translation="MGKERREQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(9931..10074)
                     /locus_tag="VW361_001202"
     CDS             complement(9931..10074)
                     /locus_tag="VW361_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEU9744244.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            10308..12026
                     /locus_tag="VW361_001203"
     CDS             10308..12026
                     /locus_tag="VW361_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU9744245.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIETPFAVEVADVETEKASGLIEVIGEVVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            12137..12484
                     /locus_tag="VW361_001204"
     CDS             12137..12484
                     /locus_tag="VW361_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9744246.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGALSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(12762..13598)
                     /locus_tag="VW361_001205"
     CDS             complement(12762..13598)
                     /locus_tag="VW361_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9744247.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(13611..14240)
                     /locus_tag="VW361_001206"
     CDS             complement(13611..14240)
                     /locus_tag="VW361_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9744248.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAESYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(14250..14891)
                     /locus_tag="VW361_001207"
     CDS             complement(14250..14891)
                     /locus_tag="VW361_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9744249.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(15037..16266)
                     /locus_tag="VW361_001208"
     CDS             complement(15037..16266)
                     /locus_tag="VW361_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU9744250.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLNTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(16256..17422)
                     /locus_tag="VW361_001209"
     CDS             complement(16256..17422)
                     /locus_tag="VW361_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9744251.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            17566..18579
                     /locus_tag="VW361_001210"
     CDS             17566..18579
                     /locus_tag="VW361_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU9744252.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(18624..19043)
                     /locus_tag="VW361_001211"
     CDS             complement(18624..19043)
                     /locus_tag="VW361_001211"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU9744253.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(19054..20460)
                     /gene="atpD"
                     /locus_tag="VW361_001212"
     CDS             complement(19054..20460)
                     /gene="atpD"
                     /locus_tag="VW361_001212"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU9744254.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(20546..21424)
                     /locus_tag="VW361_001213"
     CDS             complement(20546..21424)
                     /locus_tag="VW361_001213"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU9744255.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLSDQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(21440..22945)
                     /locus_tag="VW361_001214"
     CDS             complement(21440..22945)
                     /locus_tag="VW361_001214"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU9744256.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYAGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(22960..23496)
                     /locus_tag="VW361_001215"
     CDS             complement(22960..23496)
                     /locus_tag="VW361_001215"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU9744257.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(23496..23990)
                     /gene="atpF"
                     /locus_tag="VW361_001216"
     CDS             complement(23496..23990)
                     /gene="atpF"
                     /locus_tag="VW361_001216"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU9744258.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(24004..24720)
                     /gene="atpB"
                     /locus_tag="VW361_001217"
     CDS             complement(24004..24720)
                     /gene="atpB"
                     /locus_tag="VW361_001217"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU9744259.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKIQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(24755..24955)
                     /locus_tag="VW361_001218"
     CDS             complement(24755..24955)
                     /locus_tag="VW361_001218"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU9744260.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(25030..>25278)
                     /locus_tag="VW361_001219"
     CDS             complement(25030..>25278)
                     /locus_tag="VW361_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9744261.1"
                     /translation="YYAHPYASWERGTNENHNRLIRRWLPKGTKKMTPKEVAFIEKWI
                     NNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRFQ"
BASE COUNT         7561 a         5460 c         4588 g         7669 t
ORIGIN      
        1 tatattatag cacattttta aatctaggtt tactagattc tctggctcta tctatttatt
       61 cggaaaagaa agcttttctt cagaagaaag ctagtagctt atttgaaatt ttctcctctc
      121 tgttggatag tcccgtctat ctatgttata atgaaagaag gatttaaaat cggaaaagga
      181 gtatttatgc taaaattagg tgtcatcgga actggcgcta tcagccatca tttcatagaa
      241 gcagcccata ccagtggaga ataccaactg gtcgcaatct attctagaaa actagaaact
      301 gcaacaacct ttgcttctcg ctatcagaat atccaactat tcgatcaatt agaagtcttc
      361 ttcaaatctt cttttgattt agtttatatc gccagtccaa actccttaca ttttgctcag
      421 gcaaaagctg ccttgtctgc tggtaaacat gttattcttg aaaagccagc tgtcactcaa
      481 ccacaagaat ggtttgattt gattcaaaca gctgaaaaaa ataactgttt tatctttgaa
      541 gcagctcgta attaccacga gaaagccttt actactatca aaaacttttt agcagataag
      601 caagtgttag gagcagattt caactatgcc aaatactctt ccaagatgcc tgacttgttg
      661 gctggacaaa caccaaatgt cttttcagac cgttttgctg gtggagccct catggatttg
      721 ggaatttatc ccctctatgc tgctgttcgt ctttttggaa aagctaatga cgcgacttac
      781 catgctcaac agcttgacaa tagcattgac ctaaatggag atggtatcct cttctaccca
      841 gactatcaag ttcacatcaa ggctggaaaa aacatcactt ccaatcttcc ttgcgagatt
      901 tatacaacag atggaacctt gactctcaac acgattgagc atattcgctc agctattttt
      961 accgaccacc aaggaaatca agtccagctt cctatccaac agactcatca tacgatgact
     1021 gaggaagtcg ctgcatttgc acacatgatc cagcaaccag atctgaatct ctaccaaact
     1081 tggctggatg atgcaggctc tgttcatgag ctactatata ccatgcgcca gactgctggc
     1141 attagatttg aggcagaaaa atgaaaacca aactaccgac tgaatggcaa gaactgagtg
     1201 accaactcgg tttccaagaa ttcaccccca ttcaaactca actatttgat ccccttctta
     1261 ctggagaaaa cctcctagga gtgagccaaa ccggaactgg taagacccta gcgtatctcc
     1321 taccaagtct tctcagacta caaaagaaaa aagcccaaca actcttgatt ctagcaccaa
     1381 acacggaact tgctggacag atttttgatg tatgtaaaac gtgggcagaa gctatcggat
     1441 tgactgctca actcttcctt tcaggttcaa gtcagaaacg acaaattgaa cgccttaaaa
     1501 acgggccaga aattctgatt ggaactcctg gccgtatctt tgaactcatt aaacttaaaa
     1561 aaatcaagat gatgaatgtg gaaaccatca tcctggatga atttgaccaa ttactagatg
     1621 attctcagat tcactttgta gaaaaaatca ctcactacgc acctcgtgac caccaactgg
     1681 tctacatgag tgccacgacc aagtttgacc aagaaaagat tgtgccgaat acacgcacta
     1741 ttgatctctc tgatcaaaaa ttggacaata tccagcattt ctacatgcag gtagaccaac
     1801 gtcatcgagt ggatatgcta cgaaaactgg ctcatgtaga ggatttccgt ggtctagtct
     1861 tcttcaatag cctgtcagac cttgggaatg ccgaggaaaa actacagtat cgtgatatat
     1921 tggctgtttc cctcgctagt gatgttaatg ttaaatttag aaaaatcatc ttagaaaagt
     1981 ttaaagataa ccaactaacc ctgcttcttg caactgacct tttggctcgt ggaattgata
     2041 tcgatagcct agaatgtgtc gtaaactttg atattcctag agatagcgaa acctacacac
     2101 accgtgctgg ccgtactggt cgtatgggca aggaaggtta tgttatcact ctcgtcactc
     2161 atccagaaga aatcaaaaaa cttaaaaagt ttgcaagtat ccgagaaatt gtcctaaaaa
     2221 accaagaact ctatatcaaa taaagcccca ttgctctata cacatccagt gtatggagct
     2281 tttttataag caattcaatt ttatactcat ctgctttcaa aaagcattct agtccatctc
     2341 cgattaacga tggactttat cacctccttc tccaatcctt gtatgacatc ttgaagttga
     2401 ttcatgacat cttccaaaat tcgaaaggct ttattcttaa atccacgttt acgaatctct
     2461 ttccacactt gttcaatggg gttcatctct ggtgtgtatg gaggaataaa tgcaaaacca
     2521 atattagtcg gaatctttaa gatacttgat ttatgccata tagcattgtc cataacgagt
     2581 aaaaaataat catctggata agcttgtgaa agctcttcta aaaaggcgtt catccactca
     2641 gtattacatc taccagctat taagaaaaat gattcgcctg tatgggcatc aacagctcca
     2701 taacaatagc gaaattctcg tatatagtga ctatggatat gtggacctac tcctattgga
     2761 gcccaacaag atcccagttt actgattcta ccgaaaccag cctcatcttg gtacatcaag
     2821 cgaaccttac gaaaacgtct actggtttta aagcgctttc ttgtcttctt gaattgagat
     2881 tttattttta gacgcgacaa tggtttgagc gtctgctttc ttaggatgtt ctggacgtgg
     2941 cataatattt cgccaaccat ggcgcttcaa cagttgatag aaggcatcac gtgtgtagga
     3001 acgacctaac tcctttttat aagcctgaaa taaggcatca attgtaacaa attctcctgc
     3061 ctctgcagcc ttcaaatggc gggcaagaaa gactttctct tcctcaactg tcatatatgc
     3121 atggttacga ccaccacgtg tttcttgaag gagagagtcg agtccgaact cctcatattt
     3181 ttttacattt cgccaaatca ttgtttgatt acagtctaaa agttctataa tctctttata
     3241 agatttgccc atatcagacg aaatagaacg atttgaagac gtttatgata tttagctgta
     3301 cgagagtctt ttaaaagtgt tttgatggtt tggatttctt ctttaattga tttcatatta
     3361 ctattgtata atgctttttg attttagtct agtattatac tcttcgaaaa tctcttcaaa
     3421 ccgcgtcagc ttcgccttgt cgtatagatg ttactgactt cgtcagttct atctacaacc
     3481 taaaaacagt gttttgagca gtctgtagct aactttctat agtaaaatga aataagaaca
     3541 agacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag taaatgtgta
     3601 ctattctagt ttcaatatat tatagtttgc tctttgattt tcattgagta ttagttcaat
     3661 atctaaaaaa agaaccttgc caagcaagat tcttttagtg tctgacttaa ataattgttc
     3721 ttctgggaac taaatcgaat taagcttcga tttctgtaac catacctgaa ccaacagtac
     3781 gtccaccctc acggatagag aatgtagtac cttgttctac ggcgattggg tgaatcaact
     3841 caacgtcgat tgtcacgtta tcaccaggca ttaccatttc agtacctgct ggaagttcga
     3901 ttgaacctgt aacgtcagta gtacggaagt agaattgtgg acggtagttg ttgaagaatg
     3961 gagtgtgacg tccaccttct tctttagtaa ggatgtagac ttcacctttg aatttagtgt
     4021 gtgggttgat tgaacctggt ttagcgataa cttgtccacg ttcgatttca tcacgttgaa
     4081 caccacgaag aaggacacct acgttatctc cagcaagacc ttcgtcaagt tgtttacgga
     4141 acatttcaac accagtaaca actgcttttt gagtttcttc tttgatacca acgatttcga
     4201 tttcgtcgtt gactttaacg ataccacggt cgatacgtcc tgaagcaact gtaccacgtc
     4261 cagtgattga gaatacgtcc tcgactggaa gaagcaatgg tttgtcagtg tcacgttctg
     4321 gttctgggat atactcatca actgtgttca tcaattccat aacgatgtct tcgtatttag
     4381 agtcaccttc aagagcttta agtgctgaac cttggataac tggaagatcg tcacctggga
     4441 agtcgtattc tgacaatagg tcacggattt ccatttcaac caattcaagc aattcttcgt
     4501 cgtcaaccaa gtcaactttg ttcatgaaga cgataaggtg tttaacacca acctgacgtg
     4561 aaagaaggat gtgctcacga gtttgtggca ttggtccgtc agttgaagct actacaagga
     4621 tagctccgtc catttgagca gcaccagtga tcatgttttt aacgtagtcc gcgtgtcctg
     4681 gagcgtcgat gtgagcgtag tgacgttttt cagtttcgta ctcaacgtgc gcagtgttga
     4741 tagtgatacc gcgttcgcgt tcttctggag cagcatcgat agacgcatag tctttaggtt
     4801 ggttaactga tgaaggcaag cgacgtgcca aaacagttgt gatagctgca gttagggtag
     4861 ttttcccgtg gtcaacgtgt ccgatagtac caatgttaac gtgtggttta ctacgatcgt
     4921 atttttcttt tgccatttga gtaaaagcct ccaataaaat atattttata gatagacagt
     4981 aggcaataca gtctaacttt ccttactatt ttatcaaatt tcagctaaat tgcaagtgtt
     5041 ttacaacgtt tttgtgaatt attcttgata aaaatttaac taactaatag aaagtactaa
     5101 atagacttat ccttcaagga gttttcagca ttatccatcc actcacttgc tgaaaatgta
     5161 aacagtctct ggtttatata gtaaaatgaa acaagaatag ggcaaatcga tcaggacagt
     5221 caaatcgatt tctaacaatg ttttagaagt tgaggtgtac tattctagtt tcaatctact
     5281 atacaacctc aaaactgtgt tttgaacaac ctgcggctag cttcttagtt tgccctttga
     5341 ttttcattga gtataaaatt gcagataaaa cgataacaat cataggactc agcagagtca
     5401 atgtaggtcg aagaatagcc ctcctaatcg cttattttat agcaaaatga aatagaaact
     5461 gaacattttg ttgaggaagg taaatcaatt cctcacaatg tttgagaaag aagggaggac
     5521 tattccaact tcaacccact ataaagcaga cttacaagat agggaaccca tctccgataa
     5581 tatatagtag aatgaaaact gcacaatttg attggagaat tcaaaccaat ttctaacaat
     5641 gttttagaaa caagggtcta ttatttcaac tgcaacctac tatagcccat tgaagctgga
     5701 atagcccact gagacttcta aaccactgct ggagaggagt ttgtttagag tttctttcat
     5761 ttccctaaaa aatcaaaaag agagaaccag tctgatcctc tcttacttat agatggtgct
     5821 cactcaaatg ttaaaggagc tatttcttag agataaagga atttgaatac agctactgcc
     5881 gcaattgctg ctgcgatagg tgctactact ggtacccaag aataccacca ttttgaatcg
     5941 cctttatgct caccaagaac tgattttgga aggaaagcat gaaggagacg tggtcccaag
     6001 tcacgggctg ggttcaaggc aggtcctgta ggtcctccaa gtgatgttac caaagccata
     6061 acgaggaatc caagtgccaa gtgagccaca gaaagtcctg aagcagtgtg tggagccacc
     6121 tgtgctttaa tagccaagtc agaaaaatca actgtttgtc ctgcttctat tgccttttgt
     6181 ttcatgaatt gaagcacttc agcaccaaag aagtttttag tcaaaccaag agctgcaaag
     6241 aacaaaacaa atgaaccaac aaactcatta atcaaaccat tgacagttgc tgtatagcga
     6301 ctttcttttg taccatggtc aatacttgaa atagttgaga aagttcccaa gatgttattt
     6361 ggtttttcag ttttcaagta gaatggacgg tatgttgcca caactaaggc ttggccaaag
     6421 atagccccca agacttgcgc gataatgtaa ggtaccactt gtgcccaagg gaaaagaccg
     6481 ctaactgcaa gccctagagt gaaagcaggg ttgatgtgat tcccagatac gttaccaaac
     6541 atcaaggctg ggatcataac ccccatacca taaccaacag cgatgacgat ccagccactt
     6601 tggtgacctt tcgtaccttt aagttcaacg ttggcaactg caccattccc aagaatgatc
     6661 aaaatggcag ttcccaaaaa ttcagtggca tacttcagtg cccatgtgaa atccatttgc
     6721 tagattctcc ttaaaatttt ttagatattc cttattttat caatttttac cctatttagc
     6781 aactgatttc tggaaatatt tttaaaaaaa taggattcat agtttcccag ttcaacgtac
     6841 ttgtaagcgt ttttattctt cacgaaagac ctcattctca aaaccaggaa aaagcccaca
     6901 tctgtgatct tttccttgtt cctagattct aaaatctatt atttttcatc ttcttttttc
     6961 ttgaagaatc ctaatcctag accagctaac aaggtcatga taccagcact agccaaggta
     7021 gcattagctt ctgtacctgt gtttggcaat tcctctctct tacctgtctc ataagtcgga
     7081 acttctgggt ctggattcac tggagtttca gtttttggag tacctggttc tggagttggt
     7141 ttatctggtg ttgataaacg gtcatacctt accgttattt ctttatcact agagtctgac
     7201 gtaacttctt gtgattcaac tgttggaata tctggatctt tgtacttgtc aatcttacca
     7261 gatataacct cgtcccagtt tcctgttgtc cattcaccgt aggttacaac tcccgtgacc
     7321 ttgttctcag tttttgtacg gcttaaggtt acaggttgaa caacatcttc ttttacattt
     7381 tggttcgtaa ctttatcaac gtaatgaatg atacgcgtta tagtcttcgt ctcagtagag
     7441 gttgctgttt tgggaaccac tgtttcctca acattctcac ggtagtaata gtcaactgtt
     7501 gcaccgtctt ctggtacgca tttgcaggag ttgctaccaa ggtgtatgtt gttttccttg
     7561 tgataactcg gtcttctttg tcctcagttg ttgttttccc ttcaatagtt tttgattctg
     7621 tggtatactc agaacctatc gctaaatcag cttttataac agactctgcc aacttctctt
     7681 ggctaccttc tttatagtaa ttggctgtta ctgtagcagt ggttggcgct tcgctttctc
     7741 tataaactaa ggtcactgtt ctaccttcgc ttacaatatt cccagttaaa cttgcagaat
     7801 ttgtatctgc ttctttaaaa gtataatatt ttccgtcagt agtagtcatg ctactgagtt
     7861 ttttatctgt gacattatag ctggtaccaa tcagttgttt tttattggta atgtaggttc
     7921 cgtcactttc tttttctcca attccagtat catttttcaa tgatagcaaa cgcccttgtt
     7981 catcaacata gcgaactttc acattttctg agattagttc tgccaattct gaggtttttt
     8041 tctttttctt gatttcttcg gttattttcc ctttctcttc ttcgggaata tttagttttg
     8101 gaatgatttt ttcaacaacg gttcgtgatg gttccacagt atcttggatg actgaaaagt
     8161 cagctagaat tgggagatta tactgaacac ggtgactttg agtgtttact cctactcttt
     8221 cattattctc tgaaaatact cgtacggtat aagaaacaac atcttttcct aatagaacat
     8281 ccccagtaga gaaatagccg ccttttccta gtttgctatc tccagagtcc acttctttcc
     8341 taatcttatc agatagtttt ttaccagtca gtacattcgt tcgcacaatc cctttgtcta
     8401 cccctacaaa gtgggagaac tttttgaact cttcagaacc agatctagcc caaccattat
     8461 taagggcatt tgcttttgta tttgtattct ctctcaaagg tttggcgatt agaattatat
     8521 tcatcggcac ttagagttgc tgctatatct gactcttgaa taccaacttc cttactacca
     8581 tttctagcgg cagtatatgt gtatttatct gtttctactt ctagctgatt atccttaaca
     8641 tgataggtaa ttttctcctg gtataagagt cttcagtagt ttatatgctc tgtcatcatc
     8701 tttagcttta gaagcagctg agtttagcca agttggggta ttaggagtat ctttatcagc
     8761 ctgtttcaag acattattca agtcatttgc taacctattg gttgtcctca ctgtgaaagt
     8821 tttcttccag tctgaatcac ttttattaga cttagatatg ctcatgaaat cctggtcaac
     8881 attcaacaca atatcgcctt gttttttagc atcttccgtt gcttctgctt caaattgatc
     8941 atggagtttt tgttgctctg gtgtatagtt tttttattta cacgatttaa tgtactattt
     9001 tttattttag tattaagaac tccattaata cgatttttaa actctgcttc aaaaaatccc
     9061 ttaatttgtt ggtgcgcaag ttcaacattc aaacctttct tatacaagtc ttcattctga
     9121 acgatttcgg ctacacggtg aatggtttga tcgtataccg tcttctctta accagcagta
     9181 tccttagttt taatgactac tcgataggtt cctttagaac cgttatagtc atctagtttt
     9241 aaaaaagcgt tccaaacatt caaaaatagt tggaacttcc cttaataaat ccgtcacttt
     9301 ctttttcaag atagcccaag cttgctcaat aggattcaaa tccggtgaat aaggtggtag
     9361 aggtaagaaa aagtgtttat cttggatgca gagttcatcc aaaatgttct tgggatgaaa
     9421 actagcattg cccatgacaa taacatgagg tgtcttcaaa gcaggtagga gttgcgtttt
     9481 gaaccactcc acaaagaaat cgcttgtcat gcttttcttg taaatcatgg gagctataaa
     9541 ctctccgcct acttgtcctg caacaattga agttcgctca aaacgacgtc cgctaatctt
     9601 ttcatagact ttctcccctc taggagcccc tgcataggga cgatataggt agcggtcgat
     9661 tcctgtttca tcaatatata cgattggtaa atcttttagg ttatccaaaa tatcaagaaa
     9721 ctcagcgact ttctctgact cttgttcctt aaagctcgtc atcttttttt aaagtgacct
     9781 taatctgctt taaagctgcc catactgaag gaacagcaca atcaaaatgt gccgcaattt
     9841 cccgtaaaaa agcatctgga tgagcctcta caaaggcttt caattcctct aaaggaatct
     9901 ttcggttttt gacgactcgc tttttcctct ctatgtgtcc ttgttcacgt ctttcttttc
     9961 ccacgtgaag agagttctga cgccaacacc aaaaaacttg gctgcctcga catgactgtg
    10021 cccctctttg atggaatcta atgctcgctg tttaaaatca gtactatatg ccatagcttt
    10081 attataacat gtattttata aactaagcta ctatatcaat gttttgttat gagaagactt
    10141 acttttttta ctgaaattga atttttcctc gcctcaacat catataaccc caaaattcaa
    10201 tctgacctgg tttgaagaga tgttcgaagc agataaggtt ttactaaaac taaaaaaaat
    10261 gatataatca aactgattaa atgttttaaa aataaaggag aatttgaatg tcttaccaag
    10321 aaaattacca gaaatgggtt gattttgtgg agcttcctga ctatcttcgt caagatttgg
    10381 aaaatatgga cgaaaaaact aaggaagatg ccttctatac aaatcttgaa tttggtactg
    10441 caggtatgcg tggcttggtt ggtgctggta caaaccgtat caacatctac gttgttcgcc
    10501 aagctactga aggattggct cgtttgattg agtcaaaagg tggaaacgag aaagaacgcg
    10561 gtgtagcaat tgcctacgat agccgtcact tctcacctga gtttgccttt gaatctgcgg
    10621 cagttcttgc taaacacggc atcaaatctt acgtatttga aagccttcgt ccaactccag
    10681 aactatcatt tgcagttcgt catctcaact gtttcgcagg tatcatggtc acagccagcc
    10741 acaaccctgc tccatttaac ggttacaagg tttacggtga agacggtgga caaatgcctc
    10801 cacacgatgc ggacgctttg actacttata tccgtgcaat cgaaacccca tttgcagttg
    10861 aagttgctga tgtggaaact gaaaaagctt ctggcttgat tgaagttatc ggcgaagttg
    10921 ttgacataga ataccttaaa gaggttaagg acataaacat caacccagcc ttgattgaag
    10981 aatttggtaa agacatgaag attgtctaca caccacttca tggtactggt gaaatgttgg
    11041 ctcgtcgtgc tcttgcccaa gcaggatttg actctgttca agttgttgaa gcgcaagcaa
    11101 ctgctgaccc agacttctca actgtaacat cgccaaaccc agaaagccaa gcagcctttg
    11161 cccttgctga agaacttggt cgtcaagttg gtgcagatgt tcttgtcgca actgacccag
    11221 acgctgaccg tgttggtgtt gaagttcttc aaaaagatgg tagctacctc aacctttcag
    11281 gtaaccaaat cggtgctatc atggctaaat acatcttgga agctcacaaa aacgctggaa
    11341 ctcttcctga aaatgccgct ctctgcaaat ctatcgtttc aactgacttg gtaacgaaga
    11401 ttgctgaaag ctacggcgca actatgttca acgtcttgac aggtttcaaa tttatcgctg
    11461 aaaaaatcca agaattcgaa gaaaaacaca accacaccta catgatggga tttgaagaaa
    11521 gcttcggtta cttgattaaa ccatttgtac gtgataaaga tgccatccaa gccgttcttg
    11581 tcgttgctga acttgctgcc tactaccgtt ctcgtggttt gacacttgct gacggtatcg
    11641 aagaaatcta taaagaatat ggctactacg cagaaaaaac aatctctgtt actctttcag
    11701 gtgtcgatgg tgctgaacaa atcaaagcga ttatggctaa attccgcaac aatgctccaa
    11761 aagaatggaa cgcaacagct atcactgtcg tagaagactt caaggcacaa actgctactg
    11821 ttgctgacgg tactgttaca aacttgacaa ctcctccaag tgatgtgttg aaatacacac
    11881 ttgctgacgg ttcatggatt gccgttcgcc cttcaggtac agaaccaaaa atcaagttct
    11941 acattgcagt tgtaggggaa accaacgaag aatcacaagc taagattgct aacatcgaag
    12001 cagaaatcaa tgcatttgta aaataaagac ctataaaaga tgagaccaac caacctcatc
    12061 ttttttcgta tcaaatctaa gcaattttag aaactttatg gcatactaga cttatcaatg
    12121 aaagcgaggt aatctcatgg aacaattttt agataacatc aaagaccttg aagtcactac
    12181 agttgtgcgt gcgcaagaag ctcttgataa aaaagaaact gcaaccttct ttatcggtcg
    12241 caaaacttgc ccttactgcc gtaaatttgc aggtgcattg tcaggtgtcg tagctgaaac
    12301 caaagctcac atttacttca tcaatagtga agaaccaagc caactcaatg atttgcaagc
    12361 attccgctca cgctatggaa tcccaactgt accaggtttt gttcatatta cagatggaca
    12421 aatcaacgtc cgttgcgact cttcaatgtc agcacaagaa atcaaagatt tcgcaggatt
    12481 gtaaaaaatc agctaacaag tcttaaaatc acaaaaacgc ataatgtaag gtgcaaaaac
    12541 cttgatatta tgcgttttat tgttcctaaa acagttacat cagtatttca ttacagaaca
    12601 ttttaatttt ggaagtcaaa tcaattttta acaatgtttt agaaatcaca gtgggctatt
    12661 ccatattcaa ttatccagat tcaatcgcta ttatcgtttt cctagattac aaaaaaacta
    12721 cgttttgcta atcaaaacgc agtttcagcc actattttat cttactgtcc ttcttttact
    12781 tctttggttg ctacatcttc tccaaaccat ttttggctga tttcttggaa cttgccgtcc
    12841 ttgtaaagac tagaaaaagc ttcatttatc ttcttaacca aggttgtatc ttccttacgg
    12901 gctccaaccg caaaagcttc tgtttctagt ccaactgtaa agacattata atcgtttaaa
    12961 acaccttctg cttctaaata atagtttgca tagacacggt caatcaatag accatcaatt
    13021 cgatcgtttt tcaaatcaat caaggcttca ttaaaggttt ggtattgatt cgcttcctta
    13081 ttagcgacaa tattcttcaa aatttctgga tttgcttcaa agtccgcata accagatgaa
    13141 ccagcttgag ctcctaatgt ctttccagtc atatcctttg cagtcgtgat accagatgat
    13201 ttcttcgtaa ccaatacctg ctcattcttc atatatgagt tactgaaagc caccttttca
    13261 cggcgttcgt ctgtagcgga atagccattc caaatcagat caatcgttcc ttttgtcaat
    13321 tcagcttctt tcaaatccca atcaatcggt tgccaattta ccgtgattcc gtatttttca
    13381 aaaacagctg tagctaaatc aatatcaaat cctgcataag aaccatcttt ctgagcaaat
    13441 cccattggaa caaaagtact atcaaatcca atagtaatag acttgttaga ctggtacttt
    13501 gaccaattat ctccactagt ttcgctagaa tttttcccac aagctactaa gaacaaagca
    13561 gtcatcagac tgactaatac aagcatccat tttttcatcc atttttcctc ctatttaggt
    13621 tctactttca ataatacatc tgcgatattt tcagcaaact gcaaatcatg ggtaaccaca
    13681 atctgggtca tcccaagttc cctattttgc aagattagct tctccacttc caaacgtaat
    13741 tctggatcca gggcagaagt tggttcatcg tagccaatga tttctgggtc aatcatcata
    13801 gcacgcgcca aagccacccg ctgcttttgc ccaccagata gtgagaaagg ataggactct
    13861 gcgtgtcctc ctagtcctaa ctgttccaag agtccactcg ccttcttctc agcctcttcc
    13921 tgcttcattc ccatggtctt cacaggcgat aaagtcaaat tttccagaac tgatagatga
    13981 ggaaatagtt gaaaatcttg gaagacaaat cccagtaggt tgcgcttctg caattcatcc
    14041 agctctaaag gttgtccatt ataaaagatt tgccctgaat caatggtttc aagacccgca
    14101 agcatacgta aaagagtcgt cttacctcca ccagaaggtc caacgatagc caggatttgc
    14161 ttttcaggaa tacttagact gaaatcagac aggatttgtt tgtctccaaa gactttattg
    14221 atatttcgta attctaacat agctgccccc tatctataat aactgtactt tttctcaact
    14281 tttttggaaa taattgtcac aatcccaatt aaaatcaagt aaatagctcc tgccaagaac
    14341 ataggaacca gactagcatc gcggttagca gctgttcgac tagccaagat aaggtctgaa
    14401 attccgagag cgtagaccaa agaagtatcc ttgaccaaac tcataacttc attaaagaca
    14461 ctaggaagaa cgatcttggt cacttggggc aagataatat agcgcactct gtcaaaaggg
    14521 ctaaacttca agaccttggc agcctcatac tgtcctcttg gaatagtgtc aattccccca
    14581 cggaaaattt ctgcaaagta agctgcatag ttgagaacaa aggcaataat agctgcagga
    14641 aggcggtcta aacgaatccc aatacttggg agcacataat agataaaaat cagttgcaag
    14701 agtaaggggg ttcctcgcat aacccagatg taaatgttaa tcagataatg gaggggcttc
    14761 caatggactt gcaaggcaaa ggcaatcaaa acgcccaacg gaatcgaaaa tagcaagacc
    14821 agtgcaaaga cctgtacagt cgtgctcgca ccattcagta aactcggtaa tatctcaaat
    14881 aaataagaca tactgcacct cctaaaagta attgttccta ttatagcatg aataaacaag
    14941 attaccaagt atttttgtaa aaagattcta ccatatacaa ataaaaaccg tagctatcaa
    15001 aagagataaa ctacagttct atatgtttaa acattcttac aatctctcaa acagttcttg
    15061 catttgcaca tcatctggaa ccagttttaa gtaagtgtga gcatggactt ttgcttcttc
    15121 aaaatgtccc aattcacgca agagatagat atagtgttcc agaaattctg gattgtcctt
    15181 caaatctcct gtcaactctt gataatgctc ataagcagta tccaaatcgt ccatttcttg
    15241 ataagaacga gcaatcatcc acttggtcaa aagattttct ggctcctcac tctgcaagtc
    15301 tagaatatcc tcataacgct cctgctccag ataaatagtg gctaaacgaa gcaagatttc
    15361 ttctgtatcc tcagcgtctt cttttgcagt aaggagataa ttttctgcac cactagcatc
    15421 atgcaattca taagaaaatt gtgaagcagc tagcaagagg cgagtttcaa agggattttt
    15481 ctctaatcct tgcttagcga tacgcagggc ttcttgaact tgatgttcct tatgtaaagc
    15541 ctgactgtac ccatactcat agccttcaaa gtcaggagaa atggtattaa gctgcttaaa
    15601 gtagagggtg gctttttgat attcttcttg atcaaaataa agactggcca actcaaaagc
    15661 tgttaagtca tcgtattcta actccagggc tttttctaaa aactcagtag ccgtttcaaa
    15721 tttccctaac tgagcatagg caaagccaat tcgttgatag gtggaaatgc ccgtttgctc
    15781 ataaatcgag cgattatcta actgggcata ggcttgaata gccgcttggt aattttccaa
    15841 ctcactatcc aactctgcca aacccaatat caagagagaa tcctctgagt aggtcaaggc
    15901 ctccaataat ttctcacgtg ccacatctgt caaaccttcc agctggtaaa ggtctgcctt
    15961 cagagccaaa gacgagacat accagtcact gtcagcttgg atttcctcaa gataggtaaa
    16021 ggcttcttct atttgaccat cctcgctagc aattgcagct agattaagat gaacctctgg
    16081 aaaatcctct acaattttca ggtaaatttc cttggcctga ggatagaaac caatcccttc
    16141 aagataagtt gccaactcat acagaagatc acttgaatca ttttctaaag ctttggcgaa
    16201 ataatgctca gccttagtta aatcttgctc ctccaaagcc tgtaacatct gttgactatt
    16261 gttcactctt gacttcctca ccctctaatt catatagacc actgactacc ttataccatt
    16321 cgaaaatggc tgaaatgaca accttagcag aggcataaac cggaatacca agtaaaactc
    16381 cccagatacc aaacatagat cctgaagtta acaaaacaaa gagaacatta atagggtgga
    16441 tgtttaattg acttcccaaa atcaatggag agacaaaacg gccttcaata gtttgttcta
    16501 caataaagac aatcactact ttcaaaagca tgactggacc agcaatcaaa cccaatacta
    16561 gggcaggaag catggctaga aagctaccaa gataagggac cagatttaaa ataccagcag
    16621 taacccccag cgtaaccgca tagcgtagac caataatctt gaagaagatg ataaacatta
    16681 ctgctacaat aatagccact gtcacttgcc ctcgaacata gttggacaac tgttgattca
    16741 catctgatag aacttgtcca acaggttcct tcaattttct tggaatgaat tgggtcaaat
    16801 agttacgcaa gcctttccca tcacgcaaga gataaaagag catgaaagga acgataatca
    16861 aggcaacaat cacttgagaa gctccgctaa taaaggcact cacccagttg actgcctgag
    16921 atgaaacctt acttgccaaa actgtagcct ggctagaaaa attggtcaaa acttgctcta
    16981 attgaggtct gaaatcatct ggcaggtgct gggctaccaa tccattaaca atcctatcta
    17041 tatcttctaa gtaaacagga acgtttcttg caaaggtcaa aacctgacgt tgcagatttg
    17101 gaatggcgac tgccaagccc caaatgataa agagagcgat gataacaaag acaatagtga
    17161 tagctataac acgattaacc ttatgcttct ccatccaatc aacaatagga ttcaacaaat
    17221 aatataacaa accagacaaa atgactggca acatcacaac tgctaaaaag tctaaaacag
    17281 gtgaaaatag aaaactaatc ttacttaaaa taaaaagatt caatcccaat aataaggtta
    17341 ctaaaaatac cgtaattgcc ttgttatcta aaaaccactt gaaaaaccaa gataggctaa
    17401 aatgtttctc tttttgctcc ataaatactt cctttctatt gttctctcat tataccattt
    17461 ttgaaacaaa ataactcttt tttaaagtgc ttacatctaa ttgaatgtct ttaatttgct
    17521 tgtttttgtg atataatagt cttatcttta cacagaggta tagtaatgaa agaaactgtt
    17581 tattttggaa cttatacacg tcgtacttct caagggattt acaaggcaga ctttgataca
    17641 gaaactggtc agctttcaaa tctagaactt tttgcagctg agccaagtcc aacctacctt
    17701 gcctttgacc agcaccaaca tttatacact gttggtagcc aagacgataa ggggggaatt
    17761 gcagcctatc aaactgacgg gactgtgtta aatcatgttg ttgaagaagg agctccccac
    17821 tgttatgttg ctgtcgatga aaagcgtgat ttggtttacg cagccaacta tcacaaggga
    17881 caagtccttg tttataaacg ccaggaagat ggtagtcttc tacttagtga tatggatcaa
    17941 cacagtggcc aaggtccaca tgaaaatcaa gcttcccccc atgttcacta tacagattta
    18001 acacctgacc actatctagt gacctgcgac ttgggaactg accaagtcat cacctatgac
    18061 ctcgatcaag aaggaaaatt atctaagctc tatacctatc acagcaagcc aggagcaggc
    18121 tcacgccata tcattttcca taaccactat aaaatcgctt atctcatttg tgaactcaat
    18181 agtactatcg aagttttaat ctacgatggc gttggcgaat ttgaacgtat gcaggtcatt
    18241 tcaactttac cggaagctta cgaaggcttt aatggaaccg ctgctattca tctctctaaa
    18301 gacggtaaat acctctacgc ttctaaccgt ggccatgatt ctatcgcagt atataccatc
    18361 cttgcggacg gtagcttaga gttattagaa atcgttccaa cgcatggtca gactccacgt
    18421 gattttgatt tgacacccga ccaaaaattt ctcattgttg tccatcaaga ctctgacaat
    18481 gcaactgtct ttaaacgtaa ttgtgacaat ggtcgtctag cagaactctc caacgacttc
    18541 catgttcccg aagcagtctg catccgtttt gctccttaaa acaccataaa aaatgaactt
    18601 ggtattttca agttcatttt ttcttatagt ctatttccga cattaatacg gttaatggca
    18661 cgttgcaaag caatcttagc acgacgttct tggtcaatca aatgtttgtc ttgtgcttct
    18721 tcaattgcac gttctgcacg aagtttggca cgttctgcac gactgatatc gatatcacga
    18781 gcacgttctg cagagtcagc gacgattgta atcatatcat tggcaatttc aataacgcca
    18841 ccgtttactg caatccagtt cacgtgatct ttatcatcga tacgttttac ctttacttca
    18901 tcaactgcta aaaccgcaat catattttca tgtcgtggca agatccccat ctcaccatcc
    18961 agagttcgaa ccgatacata gctggcatgg tgatcataga cgagaccatc tggtgtcacg
    19021 atctggacag ttaactgagc cataggtcac ctcttaaaat cccatttttt cagcttttgc
    19081 aatcacatct tcgatagaac ctacaccacg gaaggcatct tctggcaagt ggtcgtattt
    19141 accatcaagg atttccttaa agccacgtac agtttcagca actggaacat aagaacctgg
    19201 ctgaccagta aattgttccg caacgttgaa gttttgtgac aagaagaact ggatacgacg
    19261 ggcgcgagca accaaggtct tttcttcatc agaaagctca tccataccaa ggatagcaat
    19321 gatatcttgc aattcatggt aacgttgaag gacacgtttt acttcagcag caactgcata
    19381 gtgctcttct ccaacgattt caggtgccaa ggcacgtgag cttgaagcaa gtgggtcaac
    19441 ggctgggtag atacccaatt gtaccaactt acgttccaag tttgttgttg aatccaagtg
    19501 agcgaaggct gttgctggcg ctgggtcagt atagtcatcc gctggcacat agatagcctg
    19561 gatagaggtt acagaaccct tcttggttga tgtgatacgt tcttgcaatt gacccatttc
    19621 cgtagcaagt gttggttggt aaccaacggc tgatggcata cgacccaaaa gggcagatac
    19681 ttctgaacca gcctgagtga aacggaagat attatcgata aagagaagca cgtcttggcc
    19741 ttccacatca cggaagtatt cagcgattgt caaaccagta agggcaacac gcatacgtgc
    19801 tcctggtggc tcattcatct gaccaaagac catggctgtt ttctcgataa cgcctgattc
    19861 tttcatttcc cagtaaaggt cattcccctc acgagtacgt tccccaacac cagcaaatac
    19921 tgaaatacca ccgtgctctt gggcaatgtt gtgaatcaat tcttggatta agacggtttt
    19981 accaactccg gcaccaccga aaagtccaac tttaccacct ttaaggtaag gggcaagaag
    20041 gtcaataacc ttgatccctg tttcaaggat ttcagaagag gtagacaact catcaaaagt
    20101 tggagctttt ttatgaattg gctgacgctc tgcgtcttct gtaaaaggag cttccaaatc
    20161 aatggtatct cccaaaacgt tgaagacacg tcccaaagtt tctttaccta ctggtacaga
    20221 gattggacga cctgtgtcca atacttccat tccacgagtc aacccatctg ttgattccat
    20281 ggcgatagta cgaaccatac catctcctaa ctccaaggct acttcaagga cgatttttgt
    20341 ttttctttcg tcatttttgt agacgacaag tgcattatta atctcaggaa gtttttcccc
    20401 tgctgcaaac aaaacgtcta caacgggacc gataacctga gcaattttac ctgaactcat
    20461 ctccttctcc tattctatat aagatactgt cggttcctag ctcaactagg tcctaagttc
    20521 attttcatac gagctggact agagcctatt ctaaggcact agcacctgct acgatttctg
    20581 taatttcttg tgtaatagcc gcctgtctgg cacggttata ctgaattgtc aaatcattga
    20641 tgactttctt agcattatct gtcgctgttt gcatggctgt catacccgca gcattctcag
    20701 ctgtcttggc atcgataatg gcaccgtaaa tcatactttc tgcaaactga ggcaacaact
    20761 gctccagaat ttcttctcgg ctggtttcca attcaaaagt caagctgtac tcttcatccg
    20821 cttcatttgg atccaagtca acaatcggaa gcatttgttc cacacgcatt tgactggtta
    20881 gcgtattgac atggtggttg tagcaaacat aaagctcatc aaagagttca ttttggtaca
    20941 tttcaacagt ttttgaaata atcttacgaa cttgatcaaa gctaggttgg tctgacaagc
    21001 cacgtaattc ataaagtggt tgaataccgc gagccttaaa gaaatcagct cccatcccac
    21061 cgatacagat catttcaaaa cctttaccgt ctgggtggta ttcttctttc aactccataa
    21121 cagctttcaa aatagaggaa ttataacctc caaccaaacc gcggtctgaa gtgataacga
    21181 tatagcctgt cttcttcaca gaacggctaa tcaacatcgg attagttgaa gcaccagctc
    21241 cattaccatg aaggatatct gtcaaaagtt tacgcacttt ctgagcgtaa acttggaagt
    21301 tgcgagcagc ttcttcagag cgacctagct tagcagccga taccatttgc atggcattag
    21361 tgatttgact cgtatttttt gttgaggcga tttttgtttt aatatcattt agagacactg
    21421 ccatctgaca cctctattct tattggaagc tagattgatt gagaaactct gtaatcgcag
    21481 catccaagac tgcttcttct ggcaagtctt ttgtatcacg aatggtttcc aaaatctctg
    21541 gatgttgagc atcaaagaag gcatggaact cttcctcgaa acgaacaata tcatctactg
    21601 gaacagtatc caagaaacca tgtgtcaaag cataaagaat ggttacttgt ttctcaacag
    21661 gtaatggttt gtgaacaggt tgtttcaaga cctcaacggt acgacgtcca cggttcaact
    21721 tagcctgtgt tgctgcgtcc aagtcagaac caaacttagt aaaggcttcc aactcacggt
    21781 atgaagcaag gtcgatacga agtgtaccag caaccttctt catggctttg atttgtgcag
    21841 aaccacctac acgagataca gatgaacccg catcgatggc tggacgaata cctgcattga
    21901 agaggccatc gccaaggaag atttgtccat cagtgataga aatcacgttg gttgcgatat
    21961 aggctgagat atctcctgct tgtgtctcga taaatggtag ggctgtaatt gatccaccac
    22021 caagttcatc agaaacttta gctgagcgct caagcaaacg gctgtggaga tagaaaacat
    22081 cccctgggaa ggcttcacga cctggaggac gacgaagcaa gagcgacagt tcacgataag
    22141 ctactgcttg ttttgataga tcatcgtata caatcaaaac atgcttacct tgatacataa
    22201 attcttccgc catagcaacc ccagcataag gagctaggaa gagcaatgga gatggttgtg
    22261 aagcagaggc tgtcacaacg attgtgtagt ccaaggcacc gtactgacga agtgtttcta
    22321 cttgcgtacg aactgttgat tctttttgtc caatcgcgac gtagatacag atcatatctt
    22381 gatctttttg gttcaagatt gtatcaatcg caatggttgt tttccctgtc tgacggtcac
    22441 cgataatcaa ctcacgttga ccacgaccaa tcggtacaag ggcgtcaata gctttcaaac
    22501 cagtttgcaa tggttctgaa acagacttac gttgcataac accaggagct ggtgcttcta
    22561 ctggacgagt tttatcagtg tggatttctc caagaccgtc aactggacga ccaagcggat
    22621 ccacaacacg accaatcaga ctttcaccta cagggacttc catgattttc cctgtacggc
    22681 ggattgtatc gccttcacgg atatctgtaa agtcacctag gatgataata ccaacgtctg
    22741 ttgactccaa gttttgagcc ataccataag agccgttttc aaaattcaac aactctccac
    22801 tcatgacatt ttcaaggcca tgagcacgcg cgataccgtc cccgatatag gttacaacac
    22861 ctgtttcagt cacatcaaaa ttgggtttga aattttcaat ttgttgctta attaaagcgc
    22921 tgatttcttg tgcgttaatt gccaaaagaa caccactttc tatttcaaat tttctttaac
    22981 aactttaagt tgttgtttaa tactcacatc aattgtcttg tgattggcaa aaatgacaaa
    23041 accaccaatg agactttcat cgatttgttc ttttacactc cttactttca gagacatttt
    23101 tttctcaatc aaagggagca aacgagtctt ctgttcatca gttagaggat gagcagacgt
    23161 aatcgtcact tcaaatcgat ttgtttcttt ttcaagtcgg ttcaagcaat ctacaagcac
    23221 atcataaaaa agatttgctc tgtgattgta ggccagaacc tggataaagt tttgtaataa
    23281 aggcgacaca gaatcttgga aaaaagcaat tgttttttcc ttatccgact cgtctactgc
    23341 cacttgtttt aaaaaagaag gcagacctgt tttttcaaca acttgcttga tttgagtcaa
    23401 gtctgaaaag atacggtctt cttctccttt ttcaagtacc aattggacaa aaggcatgct
    23461 gtatttttca attaccttta ctgttttctt gtccattaag cttctcctag ctgatcgata
    23521 tactgatcaa tgagtgcttt atgggcatga ctgtcaaggt tttgtgagat gattttacca
    23581 gctaagctga tggtcaaatc tgcgacctca cccttaacac tctgtaaagc ttctacttta
    23641 ttttgagcaa tttcttgatt ggctttttct tttaagtgtc ctgcttctag tttagcatct
    23701 gctaagatat tagccttact ttgctcagct gtttcctttg cattttcaat gattgtctta
    23761 gcttctttac ggctaccagc caattcatct tcgcgttttt gagccaatac ttctgctttt
    23821 tgacgggctt cttcagctct gtcaatatct gaagcaattt tttcagctct ttcttcgaaa
    23881 atgcctgtaa tattagacca tgcaaatttt ttaatcaaga ctagcaaaag aataaaagag
    23941 ccagtgatta aaataaaatt accaattaat tcacctactg ttacgtgcat cagttactcc
    24001 tttctattcc tcttcaatat taatcttatt ccctaaatac acagatgtca aaagagtaaa
    24061 aacataagct tggatgcagg aaataaagac agaaaatgca gtccaagcca aattagctcc
    24121 aaaggctact ggataccaat aaatagcttg gtgggaaaga agaagtaaca aactcgtcat
    24181 gacctctcct gcaaagatat tcccaaaaat ccgcaaagcc aaagataaga agtttgtaaa
    24241 ttcttccaag atattcatcg gtatgacaaa aacaggactc ataaaagatt ttatactttt
    24301 tttaaatcca cgacgacgaa cgctttctat atgtgtcaac aaaatgacaa gaaaagataa
    24361 ggttaagtca tactgtaaat tagcggttgg cgaactccac cagttagtcc catcgatcgt
    24421 ttgaatcttt gtcattaagc caaggttatt ggcaatcacc atgaaaagga ataaacaaag
    24481 gaaaaagagt gagtaatctt tcatgtagcg cgaaccaatg ttaggttctg taaatccaat
    24541 aacaaagtca tagacatact caagtacatt ttgctttcct ttgggtttca aggtcatatt
    24601 gcggcttgcc caataaataa agacaaaaat aactcccaca atcaacaaag tcatggctaa
    24661 catagtcaga ttgaagataa caggaccaat agagatgatt ggattaatac tttcttccat
    24721 ctaaaatcct cccttttctt ctcgttccat gtatttattt gataataaat gagaagacaa
    24781 gagttacaaa gaaagttcct tcaataaagg caacacctaa aaacatcaaa ctacgaaact
    24841 cagaaagcat atctggttgg cgagctactg atttaaacag tccattcatc aataaacctt
    24901 caccgacaga tacgcccata caggcaatac ataagcctaa aaatgttaaa ttcataacaa
    24961 attctccttt aaaataaaat ttacttactt agtgtagtcc taaaatttaa atttgtcaac
    25021 ttttaaccgc tattggaagc gtttaataaa aattatttcc attttgctaa atttcaagtt
    25081 caagttagcc atccagaagt cttctctggg tgacttgtag tccaagcatt ttttaggata
    25141 gttgttaatc cacttttcga tgaatgcgac ttctttggga gtcattttct tggttccctt
    25201 aggtaaccat ctacgaatga gcctgttgtg attctcatta gttccccttt cccaagaggc
    25261 atagggatgt gcataata
//
LOCUS       DAVKMO010000026        25171 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVKMO010000026 DAVKMO010000000
VERSION     DAVKMO010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25171)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25171)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25171
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.026"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            125..2398
                     /locus_tag="VW361_001220"
     CDS             125..2398
                     /locus_tag="VW361_001220"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU9744262.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            2415..2885
                     /locus_tag="VW361_001221"
     CDS             2415..2885
                     /locus_tag="VW361_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9744263.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(2979..3179)
                     /locus_tag="VW361_001222"
     CDS             complement(2979..3179)
                     /locus_tag="VW361_001222"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744264.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(3450..6726)
                     /locus_tag="VW361_001223"
                     /pseudo
     CDS             complement(3450..6726)
                     /locus_tag="VW361_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562199.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(6831..7937)
                     /locus_tag="VW361_001224"
     CDS             complement(6831..7937)
                     /locus_tag="VW361_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9744265.1"
                     /translation="MKKVKLGEVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSTEIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWRGRSAVLNQHIFKVVLDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIIVPYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNT
                     KNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLR
                     INSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLAL
                     QNEFADFVALVDKSQFACEIAIKVWRNSLKFSII"
     gene            complement(7971..8936)
                     /locus_tag="VW361_001225"
     CDS             complement(7971..8936)
                     /locus_tag="VW361_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9744266.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(9054..9467)
                     /locus_tag="VW361_001226"
     CDS             complement(9054..9467)
                     /locus_tag="VW361_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU9744267.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(9464..9700)
                     /locus_tag="VW361_001227"
     CDS             complement(9464..9700)
                     /locus_tag="VW361_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU9744268.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            complement(9760..10161)
                     /locus_tag="VW361_001228"
     CDS             complement(9760..10161)
                     /locus_tag="VW361_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9744269.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            complement(10174..11667)
                     /locus_tag="VW361_001229"
     CDS             complement(10174..11667)
                     /locus_tag="VW361_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9744270.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            complement(12175..12894)
                     /locus_tag="VW361_001230"
     CDS             complement(12175..12894)
                     /locus_tag="VW361_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9744271.1"
                     /translation="MIAKPDNGVGAAATFKLETEDDINHFKQEWDHSTLYFFEKFVTS
                     SEICTFDGLVNKDGKIVFSTTFDYAYTPLDLMIYKMDNSYYVLKDMVPKLRKYGEAIV
                     KEFGMKERFFHIEFFREGDDYITIEYNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGE
                     EFPASEFEPQYCLATSRRANAHYVYSEENLLAKYSQQFKVKKIMPEAFAELQGDYFYM
                     LTTPSRQEMDQMIADFGQRQE"
     gene            complement(12912..13319)
                     /locus_tag="VW361_001231"
     CDS             complement(12912..13319)
                     /locus_tag="VW361_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoylphosphate synthase"
                     /protein_id="HEU9744272.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPINRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKQ"
     gene            complement(13377..14072)
                     /locus_tag="VW361_001232"
     CDS             complement(13377..14072)
                     /locus_tag="VW361_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU9744273.1"
                     /translation="MHIEHLSHWSGHLNREMYLNRYGHGGIPVVVFASSGGSHNEYYD
                     FGMIDACASFIEEGLVQFFTLSSLDSESWLATWKNAHDQAEMHRAYERYVIEEAIPFI
                     KHKTGWFDGMMTTGCSMGAYHALNFFLQHPDVFTKVIALSGVYDARFFVGDYYNDDAI
                     YQNSPVDYIWNQNDGWFIDRYRQAEIVLCTGLGAWEQDGLPSFYKLKEAFDQKQIPAW
                     FAEWGHDVAHDWE"
     gene            complement(14094..14918)
                     /locus_tag="VW361_001233"
     CDS             complement(14094..14918)
                     /locus_tag="VW361_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9744274.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(15055..16269)
                     /gene="thiI"
                     /locus_tag="VW361_001234"
     CDS             complement(15055..16269)
                     /gene="thiI"
                     /locus_tag="VW361_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU9744275.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGFVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(16278..17420)
                     /locus_tag="VW361_001235"
     CDS             complement(16278..17420)
                     /locus_tag="VW361_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9744276.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            17558..17986
                     /locus_tag="VW361_001236"
     CDS             17558..17986
                     /locus_tag="VW361_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744277.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKKDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            complement(18137..20362)
                     /locus_tag="VW361_001237"
     CDS             complement(18137..20362)
                     /locus_tag="VW361_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU9744278.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     INENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(20526..22478)
                     /locus_tag="VW361_001238"
     CDS             complement(20526..22478)
                     /locus_tag="VW361_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9744279.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIEEMIKSLTGHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALTELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKVIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLAISGDAEVYRAANGAK
                     VATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALSVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(22475..23386)
                     /gene="pfkB"
                     /locus_tag="VW361_001239"
     CDS             complement(22475..23386)
                     /gene="pfkB"
                     /locus_tag="VW361_001239"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU9744280.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNISNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVKLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(23383..24123)
                     /locus_tag="VW361_001240"
     CDS             complement(23383..24123)
                     /locus_tag="VW361_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9744281.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24285..24372
                     /locus_tag="VW361_001241"
     tRNA            24285..24372
                     /locus_tag="VW361_001241"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:24319..24321,aa:Ser,seq:gga)
     gene            complement(24542..24889)
                     /gene="ssrA"
                     /locus_tag="VW361_001242"
     tmRNA           complement(24542..24889)
                     /gene="ssrA"
                     /locus_tag="VW361_001242"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         7525 a         5466 c         4436 g         7744 t
ORIGIN      
        1 ttctctatat tgaatttagt actttattca tttttattgg attatttcct tttgaagtta
       61 acaattccct ttctgctttt tttttgatat aataacctta actgtcattc tatatggagg
      121 ttctatgcgt tttaatcaat atagttatat caattttcca aaagaaaatg tcttatctga
      181 actaaaaaaa tgtggctttg atttacaaaa tacagccaat cacaaagact cacttgaaac
      241 ctttttacgt cgtttctttt tcacttatca agacaccaac tacccacttt ctatcctagc
      301 agctgataaa aaaacagacc tgctgacatt ttttcaatca gaagatgaac tgacagcaga
      361 tattttttat actgttgctt ttcaactttt aggcttttct tatttggttg acttcgaaga
      421 tagtgacgtt tttcgtaaag aaactggatt tcccattata tatggtgact tgattgaaaa
      481 tctctatcag ttactcaata ctcgcaccaa aaaaggaaat actcttatcg accaacttgt
      541 tagtgatggt cttattccgg aggataatga ctaccactac tttaacggca agagtttggc
      601 tactttttct aaccaggatg tcattcgtga agtcgtttac gttgagtctc gtgtcgatac
      661 tgaccaaaaa gggctatcag acctagtaaa ggttagcatt attcgccctc gttttgatgg
      721 aaaaatccct gccatcatga cagccagccc ttatcatcag ggaaccaatg acaaggctag
      781 tgacaaggct ctctacaaga tggagggcga gcttgaggtt aagcttcctc acaagattga
      841 gctagagaaa cctcaactaa atctcgtcca accccaaggt aaagctgagc ttatagcaga
      901 ggctgaggaa aagctaactc acatcaactc tagctataca ctaaacgact acttccttcc
      961 gagaggcttt gccaatctct atgtctcagg tgttggtacc aaagactcga caggtttcat
     1021 gactaatgga gactaccagc aaatcgaggc ttataaaaat gtcatcgatt ggcttaacgg
     1081 ccgttgccgt gcctttactg atcacacgcg ccagcgtcaa gtcaaggctg attggtcaaa
     1141 cggaaaagtt gctacaacag gactttccta tctaggtacc atgtccaatg gtcttgcgac
     1201 tacaggagtc gatggtttag aagttatcat tgccgaggca ggaatttcat catggtacaa
     1261 ctactaccgt gaaaacggtc tggtgactag cccaggtggt tatccaggtg aggactttga
     1321 ctcccttgct gagttaacct attctcgtaa tctcttagct ggcgactata tccgtggcaa
     1381 tgaagctcac caagctgact tagaaaaagt gaaagctcag ctagaccgaa aaactgggga
     1441 ctacaatcag ttttggcatg accgcaatta tctgctcaat gcccataaag taaaggcaga
     1501 ggttgtcttt actcatggtt ctcaggattg gaatgtcaaa ccacttcatg tttaccagat
     1561 gttccatgct cttcctactc atatacacaa gcatctcttt ttccataatg gtgctcatgt
     1621 ttacatgaac aattggcaat caattgactt ccgtgagtcc ataaatgcct tattgaccaa
     1681 gaaattacta ggacaggaaa cagactttca acttcctact gttatctggc aggacaatac
     1741 agctccacag acttggttat cacttgataa cttcggtggg caagaaaact gtgaaacctt
     1801 ctcacttggt caagaagagc aagctattca aaaccagtac ccagataagg attttgagcg
     1861 ctatggtaag acataccaaa ccttcaatac agagctctat caagggaaag ccaatcagat
     1921 tactattaac cttcctgtga ctaaagatct ccacctaaac ggtcgcgctc agctcaatct
     1981 tcgtatcaaa tccagtacaa acaaggggct cttatctgcc caactgctag aatttgggca
     2041 aaagaaatac ctacaacctt atccagctat tttaagtgct agaaccattg ataacggtcg
     2101 ctatcacatg ttggaaaatc tctgtgaatt gccatttaga ccagaggcac aacgagtcgt
     2161 gacaaaaggt taccttaatt tacaaaatag aaatgattta ctgttagtag aggatattac
     2221 tgcagatgaa tggatggacg ttcaatttga actgcagcca actatttaca agctaaaaga
     2281 aggagacact ctccgtttag tcctctatac tactgacttt gaaatcacca tccgtgacaa
     2341 tacagactac cacttgactg tcgacctcgc tcagtccatg cttaccttac cttgctaaaa
     2401 ggagttacat tattatgaat aaatcagaac accgccacca acttatacgc gctcttatca
     2461 caaaaaacaa gattcataca caggctgagt tgcaagccct tcttgctgag aacgacattc
     2521 aagtaaccca ggcaaccctc tcacgcgaca tcaaaaatat gaacctatca aaagtccgcg
     2581 aagaagatag cgcttattat gttcttaaca atggttccat ctcaaaatgg gaaaaacgtc
     2641 tcgaactcta catggaagac gcccttgtct ggatgcgccc agttcaacac caagtcctac
     2701 taaaaaccct tcctggactg gctcaatcct ttggttctat cattgatact ttgagcttcc
     2761 ctgacgctat cgctaccctt tgtggtaatg atgtctgtct tatcatctgt gaagatgcag
     2821 atactgctca aaagtgcttt gaagaactga aaaaattcgc cccaccattt ttctttgaag
     2881 aataataaat gactacaact aacaattatg cttttaaaaa acctggtaga aagtctttaa
     2941 catcagaaaa cccttgatac tatgcgtttt gctctatcct aggaagattt atactcttcg
     3001 aaaatctctt caatccgcgt caacgtcgcc ttgccgtagg tatggttact gacttcgtca
     3061 gtttcatcta caacctcaaa accatgtttt gagctgactt cgtcagtctt atctacaacc
     3121 tcaaaacagt gttttgagca gcctgcagct agtttcctag tttgctcttt gattttcatt
     3181 gagtattatt tcattttctc ctgcaattga attcttgctc agctttttgt tttctatttc
     3241 tttaaaatca aagtagctct tttgttaata actcgatcaa caaacatcgt ggtacaagta
     3301 tctactttga aatttatcaa ccacttaaca actgatactg tattctagga aaacgatgac
     3361 attcttccta ataaaacttc tcatatatag cataaatttc tactcttttt aattttaaat
     3421 gagtctcagc atggcaatca ctttagaatt taagccgctt ctccagctcg attattgata
     3481 agttcaatga tttgaacaat attacgaagt actggtagtt ggtgttggaa gagtagttga
     3541 acagaaccat aagatttaaa cggctcttgc gttaacactt tcgtctctaa aaaaccattt
     3601 tctacaatgt agtctacaat caattttaca aatgaaatct gcctggcatt aagattctca
     3661 tccgacaaaa atttagaaaa aatacgattg gcagactctc tatctaagcc aataatctca
     3721 cgaaccaatc tcggaattgc cttattttca taatgacttt ggtagtctgc tttactacct
     3781 aatttttccc agagcaattt ttcaagtgca agcatatcat cagatgtcaa ctttttatta
     3841 tggtatagct tagaaatgga ctcctcatcc agatgagttt tcaaataatg ctcaactttt
     3901 tcattgtaag accgaagatc gttgacctgc aaaaatgctg tggtctcgtg aacagtggag
     3961 agtatacgat cttcaaagtt aacatagtag ggtttacggt ctgttttatc caaaaactgt
     4021 aataaatctc gaatagcaag acgaattttt tccaaatcag acaagttaac ttctttccaa
     4081 aattcaggct cctgtacttt cctgataatt tcagcctgct caaaaacctg cgggatattg
     4141 ccaatagcag aaagagctct agccgtcttc atcacttggg aaatatgaac agtggaagat
     4201 ttagctgtca gttgccccaa ctgaatatga agcaaccaca aatcaaatct cctcgccatc
     4261 tcatcttctt tatcttcatc aaataaaagc ggagagagat ttttttgaat ggtttcactt
     4321 gtaacagcag ttagattctg ccaactttcc aatttcctat agctataaac tgtatctaaa
     4381 accatacgaa ccctgaagtc caactcattt aagctctcta tacgaccttg aagttccgag
     4441 acaagctgct gacggtatgc tctcgcaaac tgatcttctt ggtattggag tccctgaagt
     4501 tctcgaatca agtccacttt gatattaaat aaacgctgag tcaacgaaac aatgtgacga
     4561 cccttctcca tctcttggat ctgcacgaaa ataatcaaaa ttatccccat aatcaaatac
     4621 caagaagttt tccttatcct gctcaggtcc aaataaatct ttacatagac gggttcctcg
     4681 accaatcatc tgccaaaact tagttttaga gcgtactttc ttgaagaaga ctaaattaac
     4741 aacctctggt acatcaatac ctgtatctaa catatcgaca gaaatcgcaa tttgaggata
     4801 cttctcctta attttaaaat catcaatcaa ggtctgataa tgcttaatac tataatcaat
     4861 cacctgagca tagtcgctcc ctttttcagg atagcggttg ttaaaaatac ctctgatata
     4921 ttccgcatga tcatgatttt tagcaaaaat aatagtttta ccaatttcat cacccgaggc
     4981 tgtctgaatt cctcttgtca tgagttcatt taaaacaatt tctactgtac ttttattgaa
     5041 aataaaggaa ttaaatacac tcccatcaat atctttttca cagctatcgt cttcaaattt
     5101 gctatcaaaa tgttcctttt cttcttcgga caaatcatca taatgtagac catccgtagg
     5161 tagtttcagt ttgatttcga tagaatgata ggctactaaa tatccgtctt taacagcctc
     5221 tttcaaatca tatgcatatg ttggaacccc attctccaaa ttaaagaatc cataggtgtt
     5281 tttatctaaa tcttgacgcg gagtagctgt taagcctaca attcttgcat caaaataatc
     5341 aaaaatggac ttgtatttct gataaataga acggtgagat tcgtcaatta tgataaggtc
     5401 aaaatgccca acagtaaaag ggcgttgatt tacttcttct tgaccactaa tcgctccaat
     5461 catggtcgga taagttgaaa agaccatacg acttgattga gctccttctt tatcttctaa
     5521 gaagttacaa acggaaagat ctgggagtaa ttttctaaac gaatcatagg cttgcttaac
     5581 caaggaagtt ctatcggcta agaagagaac gttttttacc cagttatgac gtgataagat
     5641 atcaactaga gaaactgctg tacgagtttt ccccgcccca gttgccataa ccaaaagtgc
     5701 ctgtctacga tgattagaga aagcttcaca aacgcttgca atggcatgtt tttggtagtg
     5761 acgcccggaa atatcgtccc taattttact agaaatatcc tcaagcggtt tttgaagatg
     5821 acgtctatcc atcactaatt gcaattcttc ttgagagtaa aagcctgcaa tctggcggcg
     5881 gttcggacca tcaagtatat agtgcttcaa cccatttgta ataaagcaaa ttggctgata
     5941 gccgatatgt ttctccaaag cttcagcata ttctttgacc tgtacttccc ctacttctgg
     6001 attgacagag gcttttttag cctctacaat cgctaaaatt ttcccatttt taccataaag
     6061 tacatagtca cagtaaccaa ttcctgaacc gtgcttgaga ccatcaacgg ctatctcaac
     6121 acgacagttt tcttcaaata tccatcctgc taaacggaga tcgatatcaa taaagagctt
     6181 tcttgtctct gcctcagaca attgatcaat atggaaaggc acatcttgcc gttgcgctgc
     6241 agtctcacgt ttttcagtat aagtctcttg aacttctacg gactgagcag ccatctgttc
     6301 atgaaaatca ggcagttctg gtaaactgtc ttgtaacttt atcatagatt gtggagtttc
     6361 tcggtatttg atgtttgctg aaagtggtaa gcacttctca tcaaaataac gctccacaaa
     6421 ctcattgctg taacaataat cgataaaatt aacaaactga tacaaatgat gcaaagctaa
     6481 aatcgcttct cgttccttaa tttcaccacc atgagcagca tggtttcccc accgaatcaa
     6541 cagaactatc tgcttgtgga gttcagaatc tacgatatcc ctaaaatcat catcccatac
     6601 taaagaagat agagtagcac gatagggagc ttctaaatat gaatcgtgac tatatatcca
     6661 atggacagcc tgctctaaag cacgacgcgc cataaaggca gtagccacag ttgatgtagc
     6721 aatcatattc tcagcttcaa ttcaaggttt tgaaaaagat tcatattcgt cattttttaa
     6781 aagaaagcta aaatttccca tttttttctc actttaaaca aatagtttag ctatattata
     6841 ctaaatttca agctatttct ccacactttt atagctatct cacaagcaaa ttgtgatttg
     6901 tcgaccaggg ctacaaagtc tgcgaactca ttttggaggg ctagtggggg aagggggaga
     6961 agtatttttt ttaattttgt aattggtaac tgaggctgag cacttcctga tatcactcga
     7021 ctataattat tattccttaa aacatggata ataaatttct gatttagatt tggtgtcttg
     7081 ggacgtaata ttaccatacc tgaatttata cgtaaatgtt tatattttat taattcatcg
     7141 tagtacgcta catttccaac agtacctctt gttgtcaaga ctatatcata acgctcaagt
     7201 ttgccttttc gaagtaattt atcctttgtt ttagtgataa attgctttgt atcgaatgaa
     7261 aatccgtttt tagtaacatt ctttgtattt aaaaataaac agtactcctc actaaacaac
     7321 tcatctgatt taggataatt tttgccccta tcaccatcta taatatcaaa taagttatca
     7381 atgctttcaa atattttatt ttccccaaac atctcgttaa atcgggattt tacaagtaga
     7441 ttaagctctt caagttgttc ttgtctcctt aaaatcagct tgcttaacaa atccagctca
     7501 cttgcaattc tttgttgctc tcccaaattt gtatatggaa ctataatatt atcaaaatat
     7561 tttttagtta aatgtttcat tgtggaacca tgagtatgtt ttacagcatc ttgtaaacct
     7621 ttttcaacaa catatttaaa atacgattta tctatatcta tcttatccaa aaccacttta
     7681 aaaatgtgct gatttaacac tgcggatctt ccacgccact gaaaaacccc taatgtaccc
     7741 gaccacgaaa taagaatatc accagcttca acaatgtatt ttttatcaat cgtacccgaa
     7801 taataattta tctctgttga agttttagtc agattctgta ttctgataat ctctttccct
     7861 tcagatgacc aatcttgagg tttaaaagca tagccattga taaaagtagc cacttcacct
     7921 aatttcactt tcttcatgca accacctcct cggaatatcg ggatttgctt ttaagagatg
     7981 aatttttggt gtgaatgctt gacattattt tgattgacca tggcataggc cagggttgtg
     8041 tcaatcttgc tatgacctag cagtttttgg acttgttcga taggcatacc tttatcaatt
     8101 gccttagtcg ctaaagttct tctgaactta tgtgggtgaa ccttttgtat gccgagtttg
     8161 tctcctaact ttcttaagcg aatctctaca ccagcaattc caagtctctg ggcttttcca
     8221 actagcgtta caaaaagagc agggtgacta tcttttctgt cgttaagata atttcttaaa
     8281 tgaattttcg tccgagcgtc aaaatatact ggtctctcct tctttccttt accaaagaca
     8341 acacactctc tgttttcaaa atcaatatct gaacgattca actgtacaag ctcccctaca
     8401 cgcatacctg tcgatgctag taggtctatt attgccaaat ctctcaaatt ttcacagtta
     8461 tcacgcataa tttccaaatg ttcatcagta taagtttcct tcacattttg ctcagtctta
     8521 attttcttta tccgtcgaat gggattttta atgatatatt cctcttgctc aagccaagca
     8581 aaaaaagaag acaatatacg cctaatattg tctaaatttg ccttactaca atccttttca
     8641 gactggtaat ttgctaaata actccttaaa tcatctgttg tgagttgtgt cacagactct
     8701 ttaatagcat taaacaagtt ttcaatcgtc ctctggtaat aacgaattgt ttttgagcta
     8761 cagccctcta cctgcttggc ggtaataaat agttgcaaca ggttattatt cgaatacttc
     8821 tgctgctttt ttccgtctac tagatgatgt tctaaactct ctctcaacgc tagtaattgt
     8881 tcattattta aaagaggtaa catttcttgc atgataattg taacttttga ttccataatt
     8941 tctcactttc ttattcatca ataaaaagag acaatatcag tttctgcatt acagaattct
     9001 aatattgtct gttcatttat tttcttgtgc tcattcaaat ccagcatact aggttacttt
     9061 ttgacctttt ctctaacaga atgttcagaa acccatttgg agtagcttgt cattttttca
     9121 tcagttaaag cttctactgc gatggttaca cacattttta ctgcttcttc taccgttaca
     9181 gaaaaacgat agccgtttaa ttgtaaaaat ttgaccaaaa cgaagaaagc agttctttta
     9241 ttagcattag caaaaacatg cttctttatc aattggacaa atagtatcgt tgctttatca
     9301 aaaattgttg gataaagaga cttcccaaag acaaattgtt ctggtaagtt cacaatcata
     9361 tttaaggcag aagaactaac tgtttgaatt ttctcatttg gagaataccg ttgaattgct
     9421 aaagcattta ttttttcaat ttgcttttct gtcagataga ttgtcatttt tccaccaaag
     9481 ctttgaaaac atcgtcgtat tcgtcaaata ttttatctaa atttaagtca aaggcatcat
     9541 cagatacata agaaacctgc tgccccaatt cttcaggagt aaagataatc tcaccacttg
     9601 gtaacaattt cgcttcgtat ttaacaccac ttggaatatt aaattcactt ggaatcgtaa
     9661 tggtgattga atttccttgt tttcttgttt ttactaccat ctgatttcct cctttgaagt
     9721 attataacaa atcattaccg taattacaat ggcagaatat cagccaaaat actcctgcat
     9781 cagagatttc ttcaaagttt caagttcttc cagagatttt tggattgcca attgtgattt
     9841 actttccaaa aagactccca agtaatctga tataattttt tctttgtatc gctcattctt
     9901 ttttaagacc gtaattgtac taccaacagc tcccgataat ccataaccaa ctgttcctgc
     9961 attagctcca tcccatgcta tcagaatatc atctgggagt gcttcagtca tatttaaact
    10021 ttcagtgaat tttaaattat tattatttct taaatcatct atttgaatat aacgttggct
    10081 tagagttgtt tgttcagcaa gtacagtggc tttcttgcct ttttttagag ataagacttc
    10141 ccccaacttc acttttttca tacagccacc tccctacttg agtaattttt ctaattcagc
    10201 caagccagct tgaatttctt tttctaaatc attgattttc tttaagatga cctctgttgg
    10261 ttcatactca actttttcat actcaatctc tttatattta ttgatagaca aatcataatc
    10321 attttccttt atctcagcaa ctggaacaaa gaaagattga tccgttctct gacgttctgc
    10381 ttctttttca agatgatgaa agcgttcgat aatatctgga atatcattgt cgctaatcgg
    10441 ttgtcgctta tcatccaaac ttaaaccatc cgctttcata tcgtaaaacc agactttgtc
    10501 agtaccacca ttaccagttt ttgtaaagat gagaatggca gttgaaactc cagcataagg
    10561 cttgaaaaca ccactaggca ttgagattac agcatcaagc ttatgattct ctacaatttc
    10621 ctgacgaatt cctttatgag ctttagacga accaaaaagg acaccatcag gtacgataac
    10681 tgctgctcgt ccacctggtt ttaaagttcg caagaaaaga gaaagaaaga gtaattctgt
    10741 ttttttggtt tttacggttg caagaaggtc attagaggtt gaattgtagt caagtgagcc
    10801 cttaaaagga ggatttgcta aaaccaaagt atatttatcg gcttcttcat tatcttgaga
    10861 cagcgagtca aggtaactga tttgtggatt ttctactcca tgtagcatca tgttcatcgc
    10921 cccaagtctc aacatagtcg tatccgtatc atttccatga aacatctgat tatgaaaatg
    10981 attgatatta tctgtattgg tttcccattc atctttctta cgctttaagt aacggctagc
    11041 agatactaag aagccagcag aacccatagc gggatctgag atgatatctt tgatagtcgg
    11101 ttgcatcaac tcaaccatca tatcgatgat gtgacgaggt gtacggaact gtccattttt
    11161 acctgcggtc gacaattttg ataacagata ttcatagata tctccgatat cagtaatact
    11221 ttgtttgtca ttatcaaaat ctacatctaa tcccctagtt ggaaaaacat ctaagataga
    11281 aattgccttt tgaagcgtag caggtttatt tatttgaaaa atagcttctc gcatatatcg
    11341 tgaaaaggct gtatcatctg tatccccctt gagattttta ataaacggaa aaatctcctg
    11401 agtcattaaa cgataaactt cctgagcatc tcctatattt ttaaaagttg accaacggta
    11461 ttcaggttta tcttttggaa aaactccctc ataaggaatc cctagaaatt cagcatcact
    11521 ttcacgtcca agctcgacac tatccaaatc tttcataaat aagagataag tcaactgttc
    11581 aatatttgtt aaaggatttg cgtttccttc tgtccaaaga atttcccaca gctgatcgat
    11641 tttatttttt aattcgcctg taatcatatc ttcccttttc tttagttttt aaaacttagt
    11701 aatatcatta ttttatcaga tttcaaacaa agcttcaatt aactatatct atgcgtcacc
    11761 tgaatatttt atactcttcg aaaatctctt caaaccacgt cagcttcacc ttgccgtagg
    11821 tatatgatac tgactctgtc agttctatcc acaacctcaa aacagtgttt tgagcaacct
    11881 gcggctagct tcctagtttg ctctttgatt ttcattgagt attaatagac ttgtttggta
    11941 tcctgaaaac tatatcgtat aggtgtcgtc atggatcctt ttagctgatt taaggatacg
    12001 aaaacacaat actatgactc aattgaaatg ttaaaattca atttctagcc acctaatcct
    12061 gcttcaaata gttatcgaac aagttttatg atagctacct tgttaggatg ctcttatttt
    12121 ttaccagaca aaacaaaagg attaagggag tgaatttcct taatccgata gttcttattc
    12181 ttgacgttgt ccgaaatcag caatcatctg atccatttct tgtcgactcg gagttgtcag
    12241 catataaaag taatctcctt gaagttccgc aaaagcctct ggcatgattt ttttaacctt
    12301 gaactgctgg ctatatttgg caagtaagtt ctcctcagaa tagacatagt gagcatttgc
    12361 acgacgtgat gtagccaaac aatactgagg ttcaaactct gacgctggga actcttctcc
    12421 tgcgacaatg gctgcatatc cacgatagag gtccaaggaa tgagcaaagt tataaacatc
    12481 aatggtgaaa ccacctgcag ggcggttatt gtactcaatg gtaatataat cgtccccctc
    12541 acggaagaac tcaatatgga aaaaccgttc tttcatacca aattccttaa caatcgcttc
    12601 cccatacttg cgtagtttgg gaaccatatc cttgagcaca tagtaggaat tgtccatctt
    12661 ataaatcatg agatcaagcg gtgtataggc gtagtcaaag gttgttgaga aaacaatctt
    12721 tccatccttg ttcacgagcc cgtcaaaggt acagatttcg ctggaagtga caaatttttc
    12781 aaagaaataa agggttgaat ggtcccattc ttgcttgaag tgattgatat cgtcttctgt
    12841 ctcaagttta aaggttgcgg ctgctcccac tccattatca ggtttggcaa tcattggaag
    12901 accgatttct ttcactgctt gataacagct ccaggtacca caggaacacc tgcttttttg
    12961 aaaagtttct tcatttcaga cttatatttc gtctttttga gatcctctgg tttggcacca
    13021 aaaacattga attgttctct gagtgttgcg tctagctcaa gccagtattc attgtgagac
    13081 tcgatgcggt taattggacc atgtttataa aagagaaaag ccactgcacg tttgacttca
    13141 tctatgttct caagattatc aacacgaaaa tactcggtca agctattgcg caagggctca
    13201 tccaattgct cgtaagactc ttgaccaatt cccaagactg tgatgccttt attagctagt
    13261 tcgatggtaa actgttgaaa gttttgtgga tagtagggag aaataacaag gtaattcata
    13321 ggtaactcct tttataaata gagattaccg aggaaataag gcatttgttt acgccatcat
    13381 tcccagtcgt gggcgacatc atgtccccat tcagcaaacc aggctggaat ttgtttctgg
    13441 tcaaaggctt ctttgagctt gtaaaaggat ggcaaaccat cttgttccca ggctccaagc
    13501 cccgtacaca gcacaatctc tgcctgacgg taacggtcaa taaaccagcc atcgttttgg
    13561 ttccaaatat aatctactgg cgagttttgg taaatagcat catcgttgta gtaatcaccg
    13621 acaaagaaac gtgcgtcgta aacaccactg agagcaatca ctttagtaaa gacatctgga
    13681 tgctggagga agaaattgag tgcatgatag gctcccatag agcaacctgt cgtcatcatg
    13741 ccatcaaacc aacctgtctt gtgcttgata aaaggaatgg cctcctcaat cacataacgt
    13801 tcgtaggcac ggtgcatttc cgcttggtca tgagcatttt tccaagtagc caaccaactc
    13861 tcactatcca aactagatag ggtaaagaac tggacaaggc cttcctcgat aaaggaagca
    13921 caggcatcaa tcatgccaaa atcatagtat tcgttgtgac taccacctga tgaagcaaag
    13981 accacaactg gaatcccacc atgtccataa cggttaaggt acatttcacg gttaagatga
    14041 ccactccagt ggctaagatg ttcaatatgc atttcgtttt ttcctttctt aacttaccat
    14101 ttttctgcaa aaaatctcag acaatctggt agattttctg accaagggat ttcactatgg
    14161 atggcaccag actgaacttt tagcacaaga ttatccagat gtactccccc tgctatcaaa
    14221 tcatggtaat agcaaagcga cgagtcgata taggcttgtt tgatattgcc atccatcaag
    14281 gtcttgtctg tatcatctgc ttcttctgtt cctacataga tgaagatgcg ctggtcaggc
    14341 gatagtttct ggcactcgat atagcggtta aaggcttctt ggtggagcca gtttgcagat
    14401 gaaaaaacgc ccaagcaacc aatttggtct tggtattcca aaccgataaa ctgggtaata
    14461 ttgcctccta gtgaggaacc aatcatagcc gtatgctggc agtctgcttt tgtacgatag
    14521 gtctcatcga taaaaggctt gaccacctcc atgacaaact cagcatactc cacaccctta
    14581 ccaccaaact gctgctctgg gataggagat tcttggaact tccaagccgc atactcattc
    14641 attcgcccca taccatcatt gtcaatagca acgacaatca tgcgactgat atccggattt
    14701 cgtttgatag ctgggataat cttccatgaa tatccaatga aagactcttt gctataaaaa
    14761 acattttgcc cgtcatgaaa gtatacaaca ggataggaac ggtctgtatc tttctcataa
    14821 tctttaggaa gaagaatacg tacacggcgc tccttacctg tataaggaac cttgagtttg
    14881 tgttctttca tttttagata aaagtaggat tgattcattg tcagaaaact ctctatattc
    14941 aaaattttat atcattatat catgaaaata gaaaaaagtt agttttttac ctgtttttag
    15001 aaaaaaaaac taactttttt tactgatttt cgctattctt ttggattttc tgaattagag
    15061 tagattatca atcaagtcat caacttcatc tttttcggct tgaggtgtga tttcagtaat
    15121 catgattcca gccactgctc gctcaaccaa gccttcaaca tccatacgcg cttcgtactg
    15181 ctccgcattc ttaattttag gatttgtttt tggacgatct ggtgcaaaaa tggtacaaca
    15241 gtcttcaaac ggttggattg aaatgtcaaa ggtatcgatt tcctgggcga tgtcaatgat
    15301 ttccaacttg tccatggtaa ccacaggacg aatgatggga gtgttggtaa cagcattgat
    15361 agccttcata ctttcaaggg tttggctggc tacttgacct agactttccc cattgatgat
    15421 aacaaaacca tttcgtacct cacgaatacg gtcagtaatc cgcatcataa agcgacgagt
    15481 tagagtcatc aaataagctt ctggcgcttt ggctttgatt tcctcttgaa tctctgtgaa
    15541 aggcacctcg ataaactgga tatttccgcc aaacttggtc aatttacggg tcaagtcctg
    15601 cgctttcttg agggcaccag gactagtata tggtggacta gcaaagtgaa ctgcctcgat
    15661 atccacccca cgcttaagag caagataacc tgctacaggt gagtcaatcc ctcctgacaa
    15721 catgagcatc cctttacctg aagttccaac tggcaaacca ccagccccac gaatggtttc
    15781 ataagaaaga taggctgctt cttcacgaat ctccacctga agattgatgt caggactttt
    15841 catttgaact tgcacatttg gaatggcttc gaatacagcc cctccaagtg tttggttgag
    15901 ttcacgacta tcaagttcaa agttgtggtc gctacgcttg ctagaaatct taaaggtcat
    15961 accttccttg tagatgtccc gcataatctc ttggacagaa gacttcaaaa cttctacaga
    16021 tttttcaacc ttataaacag gagaaaagtt ttgaattcca aaaacttgtt tgagagattc
    16081 tgcaactgct gtgtaatcag ctccattgag gtaagcgtgg gcacggtcgc gatctgctgt
    16141 taccttaact tgggtataga tagacaaaac gtccgaaata ttattacgaa gtttattgat
    16201 gaaacgcata cggtttttac ccttggttga caactctccg tagcgaatca taatttctga
    16261 atactgcatg aatgctccta tcttactttt ctagtttgat tgtaaatcaa ttttaacttg
    16321 gtcaaaaact gctcgacctg actcatatca ttttccaagt ctaggctaag acgcacagct
    16381 gacttggcct tatctttgtc cactcccatg gcaatcaagg taccggctgg ttttcctgcc
    16441 ttagatgaac aagctgaggt tgttgagatg aaaatatcat agtcttcaaa ggcgtgaacg
    16501 atgacttcac ctcgaacacc tttgattcca aaagtcagaa tatgaggtgc aaagtcttcc
    16561 tcatctgaaa agacaaaaat atccggatag ttcagaagag cttggtgaat cactgccttc
    16621 atctgcccag tcttgctcct aaagatatct agcttttcca tagataaacg gagagccttg
    16681 gctgtcgctg caatccctgc cacattttca gttgtcgaac gataatctcg ctcctggcca
    16741 ccacctgtaa gaagaggtgt aatcttcttg ccagatttga tatagacaaa gccaacacca
    16801 cggacaccat gaaatttatg actcgagaag gtcgcgcaat ccacccgttc tgtcagatac
    16861 ttttcagtcg gaattttggc aagcgcctga accgcatcaa cgtggaagga aatagtcggc
    16921 ttgtctgcca agaattctga aatagcctca ataggttgga tagagccgat ttcattgttc
    16981 acagccatga tggaaacgag gattgtatca ggccgtatca aacctgctaa cgcctcaaca
    17041 tcgaccaagc ctttcttatc aactggagca aaatccactt caaatccttg acttttcaac
    17101 cagagggctg actctttgac tgctggatgt tcaatggctg aaacaatgat gtgcttgcca
    17161 aactgagctt tttcaaaggc cacacccttg ataacccagt tatccccttc tgttccacca
    17221 gaggtaaaga agatttcatc gcttttctta ccgattaaat ctgcaatctg ttggcgagaa
    17281 gcatctaaga ttcgtgttgc ttggtctccc aaacgatgga gactagatgg gtttcctaaa
    17341 atttttgaag cgacctgcat ataggtttca agggcttcag gataaggctt ggtcgtcgct
    17401 gaattatcaa agtaaatcat gtttctcacg ctttctaaaa tcactccctc tattgtatca
    17461 tgaaacggag cttgcgacaa gaaagggcaa tttctctttt tttaagattt ttttaaagaa
    17521 acagagtata ataaatcata atcaaaggag agaatgtatg tctaactatc gtagaacttc
    17581 aaaaccgaaa acagaacata tcaaaaaagg ctttactgtt tttcaaaaaa ccattactac
    17641 tatcggtagt atccttggtt tgattacagc gggtatcacg atcatgaacg ccttggataa
    17701 taataataaa aatactaaaa aagaacctac gacaagccag acgacaacct ttgtcaaaga
    17761 aattcaaaaa gaatcccctc aggaaaatac tactccaaat aaggaaaata acacttctca
    17821 agaaaaaaca caacaagaag aaacgccaaa atctagcgtc aaggaagaga aaaaaaaaga
    17881 tcagaaaaca gcaactcagg actctactac acctgctaca agtaaacctg ccactgaaaa
    17941 tgaaaaacag cccaatactc caacttcaga aaataatact caatgaaaat caaagagcaa
    18001 actaggaagc tagccgtagg cagtacttga gtacggcaag gcaaagctga cgtggtttga
    18061 agagatttgc gaagagtata aaagtaatca atagccagta aaatagctcc ttccaacctt
    18121 ggaaagaagc tattttttat tgctgcaata cttttcttgg cttggtacct tcagctggac
    18181 caatgacacc tgccatctca agctcttcca tgagacgggt cgcacggtta aatccaactg
    18241 acaaacgacg ctgaatcatg gatgcactgg ctttctgtgt ttcgataacc aaagacttag
    18301 cttcttcaaa aagcggatca ccaccagcat ctccatccga aaattctcct tcattttcag
    18361 aaacctcacc tggatcaaaa ctctcatcgt agtctgcatc tgcctgagtc ttgatgaagt
    18421 tcacaatgcg ctcaacatcg tcatccgaga taaaggagcc ttggagacga actggatgat
    18481 tttcattaat cggtttaaag agcatgtctc ctcgaccaag aagtttttct gctccatttt
    18541 catccaaaat cgtacgggag tctgttcctg atgaaaccgc aaatgctaca cgagatggaa
    18601 cattggcctt aatcaaacca gagatgacat caacagatgg acgctgagtt gcaagaatca
    18661 tgtggatacc tgcagcacgc gccttctgcc caagacggat gatagcatct tccacttcct
    18721 tgctggccac catcatgagg tcagccaact catccacaat cacgacaatg aatggtagcg
    18781 gaatttgctt gtactcagac tgggaattga actcttctac cttggcatta aaacctgcaa
    18841 tattccgaac tcccaccttg gcaaagagtt cataacggtt ttccatttca tccacaacct
    18901 tttgcagagc cttgctggct ttgcgtggat tggtcacgac tggaatcaag aggtggggaa
    18961 tatcattgta aacagataac tcaaccatct tgggatcgac catcataaat ttaacttgat
    19021 ctggtctcgc cttcatgaga atgctagcaa taatgccgtt aactgctact gacttccctg
    19081 aacccgttga acctgcaact agcaagtggg gcattttaga aaggtcaaaa gctcttgcgg
    19141 ttccattaac agccttccct aaaggaattt ccaagaaatt ttctgctttc gtttgcgatt
    19201 gttcccatag ttctcggaaa gatacagtgg caatatcgga gttgggcact tcaattccga
    19261 ttagagattt cccagggatt ggtgcttcaa ttcggacatc cttggcagcc aaggctagag
    19321 cgaggtcatc tgatagattg gaaatgcggt tgacccttac accaacagcc ggcttgactt
    19381 catacttggt cactgatggc ccaatttcgg cccgttcaac tgttacctta ataccaaagc
    19441 tagcaaaggt tgcttctaag attttgatat tttctctgac aattttcttc tctttagact
    19501 gatcttttgg tttatctggt gcaaagagtt gtaagcttgg aagtttgtat tcaagggctt
    19561 ctttggctga aaaatcgacc tgaacatctt cgtcatctga gtcatcttcc tgttcaggga
    19621 atttaagttc agcttgaggc aggatgattt ctggttccac ccacttttct tctggaatag
    19681 gtggaagatt ttgaacagct tcctctgtca gaatttcacc cgtttccata tcaacaggag
    19741 gcaaatcgag taaggctttt tcagtctctt cttgttctaa tctagcctct ttctcagcct
    19801 tttggcgagc tttttcttct tgtttgacaa agcgttcctc ttttcgacgc tcgtgccctt
    19861 cccaccattt ggcaaagcct ctactgaaaa attcagcaat atcgtaaaca gaccaagggc
    19921 tgactaggag agaacccact aaaatcaaga tagaaccaat aaagtaagtt ccgatatttg
    19981 aaaagagaaa ggctgttgga atataaagag cgaccccgat caagccccct ccagcaaagc
    20041 tagtcgttcg aaaaccagtc agatctgtca caacctgagc catggtccct tttagaacgg
    20101 acttgtccaa accatatttc caaaccaagt aggcctcaaa aatcaagagt aagccagcaa
    20161 atatggtgaa aaagccagat aagagtcctt cctgttttcg tatccacttg aaaaagaaga
    20221 gatagattaa taggccgaat atcgccagat aagctaggct acccactagc aagcgaatta
    20281 aattataaag ggttatacct gcagccccta atttgaaggc tgcgaaaatc aataaaatcg
    20341 caattcctaa cgaaatcaac attcgttgaa tcgcttcttt tctttccagt tctgctttag
    20401 acggtctccg tcttgttgta cttgtattct tgtttgccat tcttctatta taccatattt
    20461 cacaggcatt tcgggaagag aaaaagactg caccaaacgg tccaatcttt tcatttttct
    20521 attttttatg cttgtggttt gcgtaggtaa ccataaacca caccacttac gattgctcct
    20581 accaagacag aaacgaggta aaggagagca tttgaagtaa gggcgataac gaagattcct
    20641 ccgtgtggcg ccatgagttt gataccagta agaccaacga gtccacctgc tactgctgaa
    20701 ccaaggatga agcttggaat cgcacgagct gggtcagcgg caccaaatgg aatcgctccc
    20761 tcagtgataa atgacaagcc catgatgatg tttgtcaaac cagagttacg ttcttcctta
    20821 gtaaatttat ctttgaaaag aagagttgcg acaaagattg caagtggtgg caccattcct
    20881 ccagccataa ctgctgccat ggctacagaa ccacctgaag aaacagttgc tgcaagcgta
    20941 cctgtaccaa agacataagc tgctttatta actggtccac ccatgtcaac agccatcatt
    21001 ccaccaagga cgataccaag aaggacagct gaacctcctc caagaccgcc taggaagtca
    21061 ttcatagcag tgttgattgc tgccattggg atattcacag ctagcataac aaatcctgtc
    21121 aagattgttc caagaagtgg caatagaagg attgatttag caccttcgag tgaacgagga
    21181 actttaacgt atttcttgat ggcaagaacc aaggcacctg cgataaatcc accaacaagg
    21241 gcacctagga aaccagatga gacacctgca agagttgaag ttgcttcacc acctgcggca
    21301 taaggaattt taccaaaggc aaaaccttct ttggcaatag caccagccac gaaacctgct
    21361 accaaacctg gtttttcagc aatagagtag gcaacataac ccgcaaagac tggaagcatc
    21421 aaaccaaagg cagctccacc aattttcatg aacatagaag ctaactcatg gtaagaacca
    21481 agattgccaa ggttttcatt tggaacactc aaagcaccgt caatcaagaa ggcaagggca
    21541 atcatgatac caccaccgat aacgaatggt aacatttgag atacaccact catcaagtgt
    21601 ttgtagaagg caccaccaag gctttgtttt tcgttagagg ctgttgcgac tttggcacca
    21661 ttagcggcac ggtagacttc cgcatctcct gaaatagcca agttgatcaa ttcttctgtc
    21721 ttacggatac cgtcagcaac tggacgattg atcaaaggtt tgccatcgaa acgatccatt
    21781 tcaacggcct tgtctgctgc aatgataata actttagcct tacggatatc ttctgcagtt
    21841 agttgatttc caacaccgct agcaccgttg gtttcgacct tgataccaac ccccatttca
    21901 gcagctactt tttgaagggc ttcttgggcc atgtaagtgt gggcaatacc tgttgtacaa
    21961 gctgtaacag ctacgataaa gtcaccagag tcattagcag gtgcttgaac aagttcctca
    22021 gttttttctg aagcttggtc aaaaagttcg ataacttggt ctgcagatgt tgcttgacga
    22081 agtttgtctg caaaaccgtc tttcatcaag tattgagaca attctgtcaa tgctgccaag
    22141 tgagtatcat tggcaccttc tggagctgca atcatgaaga agaggtcagt tgcctgccca
    22201 tccaaactct catagtcaac acccttgttt gacttagcaa agagaactgt cgcttctttg
    22261 acagcagcgt ttttgctgtg aggcatagcg attccatcac ccaaaccagt agaagttaaa
    22321 gcttcacgcg ccaaaatgcc ttctttaaag gtttcaaaat ctgtcacata accgtggcct
    22381 gttaggcttt taatcatctc ttcaatgaca gcagtctttt cagttgcctg caaatccagc
    22441 aacatgacat cttttctcaa taaatcttga attttcatcg tttttctacc tcaacttttc
    22501 catatgtttc tttaataaat tccgccgttg ccaagtcatc tgagaaggta gttgccgttc
    22561 cgcaagccac tccccatttg aaggcttcta ctgcgtcttt tgatttgaca aattcacctg
    22621 tgaatccagc aaccatagaa tcaccagctc caactgaatt tttgactgtt cctttgattg
    22681 gtttagcgaa gtaagctccc tcagatgtga caagaagggc accatcacca gccatagaga
    22741 taataacatt ttgagcaccc ttagccagta actcacgagc gtatttctca atttcatcta
    22801 aactttcgag tttaacccca aaaatcgctc caagttcatg attatttggt tttacaagaa
    22861 gaggctggta atccaaacta tcaattaagg tctgtccttc aaagtcacag accacttgcg
    22921 caccagtctg gcgcgtcaag gaaatcaaat ccttatagat aacattgcct agatttttag
    22981 cacttgaacc tgcaaagaca actgtatctt ctgctgtcag actagataaa atagctttca
    23041 attcttctag cttaaccggt tcaacagttg gacccgttcc gttgatttct gtttcttggt
    23101 ctgctttgat tttaacattg atacgagtat cttctgccac ctggacaaaa cgtgtctcga
    23161 tttcttcctc tgctaaagta tctgtgataa atttaccagt aaagccaccg ataaatcccg
    23221 tcgctgtatt tgatatattc aaacgtttca agacacggct gacattgatt cctttcccac
    23281 cagcaaactt atcatcactg tccatacgat ttacactacc aactttgact tggtccaaac
    23341 gaacgatata gtcaatggat ggattgagtg tgactgtata aatcatactt ctattacctc
    23401 cgttttctcc ttaataacct gcaagagctc atgcccttga ctagtgataa cgatagcgcg
    23461 tttgagtggg gctaccttgg caaagcaagt ttgtccaatt tttgacgaat ccaccaagac
    23521 gtaggtctgc ttggcattct ccaaaatagc tcttttcaca gctccctcct ccatatcagg
    23581 agtcgtataa tagccatcgt caacaccatt cattccgata aaggcacggt caaagtgcaa
    23641 ttggttaatc tggttaagag caacgccccc gatactagca tctgtcgccg tcttgacgtt
    23701 tcctccaacc atgacagttg gaatctgctt ttcaaccaac tgagcggcat ggtgaatgga
    23761 gttggtcaca actgtaacat tcttattgac caattcatga atcaaaaaag cagttgttgt
    23821 tccagcatcg ataaagatga catctttttc tttaatgaga gaggctgctt tctgagccag
    23881 caatttcttt tcttgaaggt ttttgacaga tttttcttga atggtttctt cttcctgtaa
    23941 ggagtggggg agttctgctc caccatgcac acgacgaagc ttattttccg cttccaactc
    24001 atccaagtct cttcgaaccg ttgattctga cgtttctagc aaactaacta atttttctag
    24061 agaaactaca tgatgttgat ttaactcctc tagaatcagt tgtttacgtt ctgtttttaa
    24121 cactgaatca cctcctgtta tcgtttacac tattcattct accatacttt atttcgaagt
    24181 caagcatttt ttatcatttt ctttcaaaat ctatcatttt tcttatttct agaattttta
    24241 ttgcaagata agagccttta tggtagacta tttgagtaag tattggaaga ttactcaaga
    24301 ggcttaagag gccgtgttgg aaacgcggta ggcgtgtaat agcgtgcgtg ggttcgaatc
    24361 ccatgtcttc cgtcgaaaaa agattatttt taggatgcaa caaatgttgt atcctttttt
    24421 aaaatagggt ctgtttgtga ctcccttttt agcaaaagaa tgcaaaggaa taccaaagat
    24481 aaaaataaaa aacgttgatt taacaacgtt ttaccaagga atgcaaaaga atgcaaagga
    24541 ataatggagc cggtgggagt cgaacccacg tccaaacacc tgccaacata tttgtctaca
    24601 accataggtt atgtattatt ttaacagccc ctcgacacat aactcaagtc tagaaactgc
    24661 gagtctatca atctcttatc aagccgctag acaaggctta atcgtatctc gctaataata
    24721 agacctgtca ttgaacacga gcaatccaaa tcgggtcacg cctgctggtt tttaggcagc
    24781 tagagcgtaa gaagtgttat tttttgcagt tatatttaac tgagcgttta cgtcgccaca
    24841 cgagtcgcaa aatatgcctc ataatgcctg tcgaatccgt aacgacccca aaagacaata
    24901 aaaccattat accttatcta actcaaaaat gcaaaaagaa atcacatacc taaaaaagat
    24961 actattcgag aaatttagca aactggaaga ctaactacaa ctttctcagt gcataacttt
    25021 acgattgtaa atagagctta cgaaatccaa ttaacacata cctaagatga agctatctgt
    25081 tttgaagaaa ttcacgaaga gaattattct aaaatacttt cagatgagaa ttttcgtact
    25141 ctctttattt taattcattt gagtttaaaa a
//
LOCUS       DAVKMO010000027        23007 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVKMO010000027 DAVKMO010000000
VERSION     DAVKMO010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.027"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            19..718
                     /locus_tag="VW361_001243"
                     /pseudo
     CDS             19..718
                     /locus_tag="VW361_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            715..933
                     /locus_tag="VW361_001244"
     CDS             715..933
                     /locus_tag="VW361_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744282.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(990..1274)
                     /locus_tag="VW361_001245"
     CDS             complement(990..1274)
                     /locus_tag="VW361_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU9744283.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(1328..2263)
                     /locus_tag="VW361_001246"
     CDS             complement(1328..2263)
                     /locus_tag="VW361_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU9744284.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            2367..2810
                     /locus_tag="VW361_001247"
     CDS             2367..2810
                     /locus_tag="VW361_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU9744285.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            2926..3192
                     /locus_tag="VW361_001248"
     CDS             2926..3192
                     /locus_tag="VW361_001248"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU9744286.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            3189..3563
                     /gene="crcB"
                     /locus_tag="VW361_001249"
     CDS             3189..3563
                     /gene="crcB"
                     /locus_tag="VW361_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9744287.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDAVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            3557..3886
                     /gene="crcB"
                     /locus_tag="VW361_001250"
     CDS             3557..3886
                     /gene="crcB"
                     /locus_tag="VW361_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9744288.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            4005..4352
                     /gene="rplS"
                     /locus_tag="VW361_001251"
     CDS             4005..4352
                     /gene="rplS"
                     /locus_tag="VW361_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU9744289.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            4394..4465
                     /locus_tag="VW361_001252"
     tRNA            4394..4465
                     /locus_tag="VW361_001252"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4427..4429,aa:Arg,seq:cct)
     gene            complement(4520..5326)
                     /gene="yidA"
                     /locus_tag="VW361_001253"
     CDS             complement(4520..5326)
                     /gene="yidA"
                     /locus_tag="VW361_001253"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU9744290.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETDTGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYTTKTNDESGVAHAIRTWVL"
     gene            complement(5339..6643)
                     /locus_tag="VW361_001254"
     CDS             complement(5339..6643)
                     /locus_tag="VW361_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU9744291.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQCNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            6715..7092
                     /locus_tag="VW361_001255"
     CDS             6715..7092
                     /locus_tag="VW361_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU9744292.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDRQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            7182..7514
                     /locus_tag="VW361_001256"
     CDS             7182..7514
                     /locus_tag="VW361_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU9744293.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILDRYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            7526..9097
                     /gene="ffh"
                     /locus_tag="VW361_001257"
     CDS             7526..9097
                     /gene="ffh"
                     /locus_tag="VW361_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU9744294.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKVLAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTSEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(9292..10575)
                     /locus_tag="VW361_001258"
     CDS             complement(9292..10575)
                     /locus_tag="VW361_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU9744295.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(10829..11542)
                     /gene="rsmG"
                     /locus_tag="VW361_001259"
     CDS             complement(10829..11542)
                     /gene="rsmG"
                     /locus_tag="VW361_001259"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU9744296.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            11636..12196
                     /locus_tag="VW361_001260"
     CDS             11636..12196
                     /locus_tag="VW361_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU9744297.1"
                     /translation="MTWIILGVIALIVVFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            12198..13097
                     /gene="htpX"
                     /locus_tag="VW361_001261"
     CDS             12198..13097
                     /gene="htpX"
                     /locus_tag="VW361_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU9744298.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRIFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINAPKKG
                     GGVQKLFYTHPPISERIERLKQM"
     gene            complement(13246..14805)
                     /locus_tag="VW361_001262"
     CDS             complement(13246..14805)
                     /locus_tag="VW361_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9744299.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIICRMTE
                     HGLKLVNLEDL"
     gene            complement(15044..15361)
                     /locus_tag="VW361_001263"
     CDS             complement(15044..15361)
                     /locus_tag="VW361_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU9744300.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EQLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYRPV
                     FEF"
     gene            15531..16073
                     /locus_tag="VW361_001264"
     CDS             15531..16073
                     /locus_tag="VW361_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU9744301.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            16073..16702
                     /gene="nth"
                     /locus_tag="VW361_001265"
     CDS             16073..16702
                     /gene="nth"
                     /locus_tag="VW361_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU9744302.1"
                     /translation="MILSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVVFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            16913..17434
                     /gene="pyrR"
                     /locus_tag="VW361_001266"
     CDS             16913..17434
                     /gene="pyrR"
                     /locus_tag="VW361_001266"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU9744303.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            17453..18376
                     /locus_tag="VW361_001267"
     CDS             17453..18376
                     /locus_tag="VW361_001267"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU9744304.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQIPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFSGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            18426..19505
                     /gene="carA"
                     /locus_tag="VW361_001268"
     CDS             18426..19505
                     /gene="carA"
                     /locus_tag="VW361_001268"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU9744305.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            19818..22994
                     /gene="carB"
                     /locus_tag="VW361_001269"
     CDS             19818..22994
                     /gene="carB"
                     /locus_tag="VW361_001269"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU9744306.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELSVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAVVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         6681 a         4395 c         5155 g         6776 t
ORIGIN      
        1 ctcgtacagc taaatatcat aaacgccttc aaatcgttct atagtaaaac gaaacaagaa
       61 cagggcaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga agtagaggtg
      121 tactattcta gtttcaatct actatatttc gtctgatggg caaatcttat aaagagatta
      181 tagatctttt agactgtaat caaacaacga tttggcgaaa tgtaaaaaaa tatgaggagt
      241 tcggactcga ctctctcctt caagaaacac gtggtggtcg taaccatgca tatatgacag
      301 ttgaggaaga gaaagccttt cttgcccgtc atttgaaggc tacagaggca ggagaatttg
      361 ttacaattga tgccttattt caggcttata aaaaggagtg tggatgaacg cctttttaga
      421 agagctttca caagcttatc cttttattcg ttatggacaa tgctatatgg cataaatcaa
      481 gtaccttaaa tattccgact aatattgatt ttacctttat tcctccatac acaccagaga
      541 tgaacccatt gaacaagtgt ggaaagagat tcgtaaacgt ggatttaaga ataaagcctt
      601 tcgaactttg gaagatatca tgaatcaact tcaagatgtc atacaaggac tggagaagga
      661 ggtgataaag tccatcgtta atcggagatg gactagaatg ctttgtgaaa gcagatgagt
      721 ataagtcctc gttttgaaac cttagagcag gccattgcct ccaaagattt ggaaaaagtc
      781 cgagaagctt ttaagaaaat gaattccact tggaccatca atgaaagtgt ggttcgtgac
      841 aatagtacag ctcattatgg acgtgttgaa acagctattt ccttcctgcc tagtagcatg
      901 gaaaccgaac ctacagatga gtctggaaca tgaaaacagc agttgatttc aagaaacaaa
      961 aaagaacagc cgaaactgtt ctcttatcat tatttgagac cgtatttttt gttgaaacga
     1021 tccacgcgtc catctgcttg agtgaacttt tgacgtccag tgtagaatgg gtgtgagtct
     1081 gatgaaattt ccacacggat caatgggtaa gtttcgcctt cgaactcaac tgtttcgtta
     1141 gagcgttttg ttgaaccgct aaggaattgg taaccagtag ttgtgtccat gaagacaact
     1201 gggcgatatt ctggatggat atcttttttc attttgcaat atttcctttc tgccatggtc
     1261 tctttgcgag ccatagattg ttaccatact agtctatcag attctgaaaa gtttggcaag
     1321 tattttatca gtttttaagc aagtttttta acttttggta gatgatttcg ttttcttcta
     1381 ggctatagga attagcacca cttgctagag ggtggcctcc accatcatgc tccttggcga
     1441 tttcattgat aggatggatt ttactgcgta agcgaactcg gtagtggcca tcagcctgtt
     1501 cgacaaaaat tccccagaga ctcactctgt caatgcgtcc aggtgcaccg acaatggctg
     1561 cagtttcagc atcggttaca ttgtattgtt tcaagacttc ttgactcagg ataacgcgag
     1621 cagcaccatt ttcatccact tccagatggt cgtagatgta gccttgcagt ttagcaattt
     1681 tgtagctcat agtgtccatt ttgcgagtga gagccgcaaa gtcaaagtta tgttctctca
     1741 aataagcagc caggcgaaga gtccgtgcag tggtagaagg gtagaggaag cgacctgtat
     1801 caccgacaat tcctgcaaag agcaactcag catcgcgatc tgccaaggct agttgggttg
     1861 tttgggcaaa tagggtaatc atctcgctag cgctacttga actagtatcg acccaagaca
     1921 ggtcaccgta tacatcatca tttggatggt ggtcaatctt aatgagaaaa tcaccttgac
     1981 tatagcgctt atcatcgata cgagcagtat tagctgtatc acagacgatg acaagtgcgc
     2041 cttggtaggc tctatcttca acaagatcca tctcagccat ccaagtaaga gttggttcat
     2101 caaaaccgac ggctttgatg gttttttctg ggaaatgatg ttccagcaag gctttcaatc
     2161 ccacctgact tcccaaggca tcagggtctg gtttcatatg acgatgaatg ataatggtgt
     2221 cgtattcttt aattttttct aaaatttgtt ggcaaatctc cataaataac ctcaattctt
     2281 tctcatttca ttgtagcaca agaattttta tttttaaaat gaaaaagatg tgatataatg
     2341 gagaaagata aattgaggag gacgatatgg cattagcaaa aattgtattt gccagtatga
     2401 ccggtaatac cgaagaaatt gcagatattg tagcagacaa attacgtgac ttgggcttgg
     2461 atgttgatgt tgatgaatgt acaactgttg acgcttcaga cttcttggaa gcagacatcg
     2521 ctatcgttgc gacctatact tatggtgatg gtgaattgcc agatgagatg atggacttct
     2581 acgaagacct agcagatctc aacttgaatg gcaaaatcta cggagtggtc ggctcaggag
     2641 ataccttcta cgatgaattc tgtaaggctg ttgatgactt tgaccgtgtc tttgtgtcaa
     2701 caggagcaga aaaaggttca gagtgtgtta aagttgatct ttctgccgag gaagaagata
     2761 ttgaacgctt ggaacaattc gcagaagaat tggctgctaa agtaggataa gcataaaagt
     2821 gcgctgatgt aatcaatcag tgcatttttc ttatcgagag ttgggatttt actagcctaa
     2881 ttgatggctt tttgatacaa taattcaaat aaaggaggag actgtatgga tttagatatt
     2941 attcgtcaag aaatcgatca aatcgacgac caaattgtca aactgttaga agaacgaatg
     3001 catttagttg agggggtggt tgcttataag aaagcttcag gtaaaccgat tttagatact
     3061 aagagagaag aagttatttt tgaaaaggtt aggagtcgtg tagaggacaa gcgctatcag
     3121 gagactattg tagcgacttt ttcggacata ctcaaacgtt cgcgtgatta tcaggatcaa
     3181 aatatcaaat gaaaaaagaa caattttatc cgctaggaat ttttctagct gctatgttgg
     3241 gcggacttgt ccgatatcta gtttccacct ggttaccagc cagtccagac tttccttggg
     3301 gcactctctt tgtcaactat ctgggaattt tctgcttgat ttttcttgtc aagggctatc
     3361 tggtctataa ggggactagt aagggcttga ttttagcact ggggacgggt ttttgcggag
     3421 gtttaacaac cttttctagt ctcatgcttg atgctgtgaa attactggat acagggcgtt
     3481 atcttagttt gatactgtat ttgcttttga gtatcggtgg aggcctgctt ttagcttact
     3541 atttggggag gaagaaatgg taatcgtcta tcttgcaatc gcctgtggct tgggagcact
     3601 cgtacggtat ttcttttccc gctacaatca agcttctaaa ttgccacttg gaacgctcat
     3661 agctaatctt ttaggttgtt ttttaattgg agtattctac aatcatgtag agtctaagga
     3721 agtatatgct attctagcaa caggattttg tggcggttta acaacttttt cgaccttgaa
     3781 tgacgaactt caaagactgc taagtgataa gaaggtcttt tattcttacc tgactttgac
     3841 ttacataggt ggtttggttg cgattttttt aggaattttg ctataaattt ctttactttt
     3901 ttgtgaaaat ttggtagact gtatcttgtg tgtgatggac gcacaaaaat acagtttatc
     3961 cgctgaggaa gtttcctcaa gattgacaaa gataggagaa taaaatgaat ccattaatcc
     4021 aaagcttgac tgaaggtcaa cttcgtacag atatcccatc attccgtcct ggtgacactg
     4081 ttcgtgtaca cgcgaaagtt gtcgaaggta accgtgaacg tatccagatt tttgaaggtg
     4141 ttgttatcgc acgtaaaggt gctggaatct cagaaaacta cacagttcgt aaaatctcta
     4201 acggtgtagg tgttgagcgt atcttcccaa tccacactcc acgtgttgaa aaaatcgaag
     4261 ttgttcgtta cggtaaagta cgtcgtgcga aattgtacta cttgcgtgct cttcaaggta
     4321 aagcagctcg tatcaaagaa atccgtcgtt aattcgacta aaaaactctg cttttcagca
     4381 gagtttttat ctagctccct tagttcaatg gatataacaa ctccctccta aggagtagtt
     4441 gcaggttcga ttcctgcagg gggcagtaat tagacatcaa aaaccgctca gctgagcggt
     4501 ttttatctat tctttccttt tacagtaccc atgtacgaat agcatgggca acgccggatt
     4561 cgtcatttgt tttggtggtg tatttggcga tttttttgat ttctggattt ccgttttcca
     4621 tgactacagg gttgccaacg acttccagca tggcacggtc attttcttcg tctccgatag
     4681 ccatggtttc atctttggtt aatcctagtt tttcagctaa gtgagtaata gctgaaccct
     4741 tgtctacatt ctttttaagg agttcgaggt agaaaggagc agatttgttg atagagtagt
     4801 gctcgtaaaa ttcggctggt attttttcaa tcgcagcatc gaggatttct ggttcatcga
     4861 tgaacataca cttgacaatt tccttgccag ccatttcttc aggagtgcgg tagaagatag
     4921 gcatgctgac gagggttgat tcgtgcacag tgtatgttcc gatattgcga ttggcggtat
     4981 agataccgtc cttagtaata gcatgcatgt gaacaccaag cttgcgactg agaaattcca
     5041 tatccagata atcctcatag gtcaaggatt cgctgataat ctcatggcca gtatcagtct
     5101 cttggacaag ggcaccattg aaggtcacca catagtcacc ttggtctctc aactgcaagt
     5161 cgtccagaag tttggcaaca cctgcgatgg ggcggccagt tgcaatcacg actttgacac
     5221 cagcttcttt ggcatcttgg atggcagaaa agacttcagg agtgatttcc ttttggctgt
     5281 tgactagggt tccgtcaata tcgacggcaa ttagtttaat actcataaaa ttcctcttct
     5341 agtttttatt tggggtaaaa tgatcgttct caatcaagtg taaaaattgc tgggtaatgc
     5401 ttgcaaagat gctgttttgg tccaacattt cttttggaaa ataaaagcga ttatctccgt
     5461 ggcgactgcc agcaagggat tggacgatag gagacaggct agagagttcg gccagttctc
     5521 catttttttg taaaatctca atctgtgtcc gtgggttttc agattcggga cgatagatat
     5581 cataagggag gtcaaagttc ttatgaatgg cagtgtagta gtcgggatca aagccgatat
     5641 cctcaaccaa ttttctcatg ctagtaagtt gatcttggtc ctcttgtgaa aaggtaatgg
     5701 atttaaagac cttgcggttg acaaagcgat gcgataaatc tgcaagaatc ttgtcaggac
     5761 tggtcatcca aagctggaag taggtattca tcacgccatc atccagagcc agatagtcag
     5821 tcaaggtcac atttttttcg aagaaaggca ggaggtgtgg agaagttcgg gcaaagaaat
     5881 ccttgtcctc aggatagagt tccttggcgc gtttgagaag attctgtagg agaacttcca
     5941 tggcgcgtgt tgcggggtgg aaataaacct gcatgtacat ctggtagcga ctgaggacgt
     6001 agtcttcgat ggcgtgcatg ccattgcact gaaaggcgat accattttcg ataggacgaa
     6061 tgactcggag gattcgagtc aggtcaaatt ccccatagga tgctcctgta aaataggagt
     6121 cacgcaagag atagtccatg cggtccgcat caatctggct agaaatgagc tgcacgacct
     6181 gcttattagg ataggtatgg tcaatgacac tggccacctt ttctgggaaa tcaggtgcca
     6241 cttgtagcag gacttggtga atctctgtct caggattttg aataatctcc tgagtaatgg
     6301 cttcatggtc tgtatcaaag agattttcaa aagtatggga gtaggcgcca tgcccaaggt
     6361 cgtgtaggag agcagcggtc atggtcaaga gagactcggc aggattccat tcctcaggat
     6421 atttttcttc gaaaatctct gtgatgcgtc gtgcaatttc atagactcct agacagtgag
     6481 agaagcgact gtgttctcca ccgtggaagg tataactgga agttcccagt tgtttgatcc
     6541 ggcgcaaacg ctgaaattct tttgtattaa tcaagtcata gatgatttga ttattgacat
     6601 ggatgtagtt gtgaactggg tcacggaata ctttttcgtt catatgacca ttatagcaaa
     6661 atcctgctct ttttggtaaa atagtaggac aagagacaag aaagaggact tgatgtgaag
     6721 attcggatgc gaaatacgat tcagtttgat gagcagttgg aagtgattga ccagctttat
     6781 gatgtggaag tgcatgaaaa gggagattat agctatttac tcttttataa tgaggaaaag
     6841 gaaaaagtag ttattaaatt tcatggtcaa gaactggtga tgagccgatt ttctaatccc
     6901 aagaccatta tgcgcttttt aaaggatagt gatagtttgg cctatattcc tacccctatg
     6961 ggcatgcagg aatttatcat tcaaacgagc cgttatcaag ttgataggca aaagattgag
     7021 ctagcttatc aactacaaaa tcaagagggg catccctttg ccagctatca attggaaatt
     7081 acttggggct aggatctcgt ttttctcaaa tctactttct atcttcaagg attggctccc
     7141 tagtgtggta gattaggcta ttttttggta taataaaagt tatggaaatc gaaaaaacca
     7201 atcgtatgaa tgcgctcttt gaattttatg cggcgctttt gacagataag caaatgaatt
     7261 atatagagct ttactacgct gatgattaca gtcttgctga gatagctgag gagtttggtg
     7321 ttagtcgtca ggctgtctat gacaatatca agcgaacaga aaagattctg gaagattatg
     7381 agatgaaatt gcacatgtac tcggactaca ttgtccgtag tcagattttt gaccaaatct
     7441 tggatcgcta tcccaaggat gattttctgc aggagcagat agaaatttta acaagcattg
     7501 ataatagaga ataagaggaa gaaaaatggc atttgaaagt ttaacagaac gtttgcagaa
     7561 cgtctttaaa aatctacgta aaaaaggaaa aatctctgaa tctgatgtcc aagaggcaac
     7621 caaagaaatt cgcttggcct tgctcgaggc cgacgttgcc ttgcctgttg taaaggactt
     7681 tatcaagaaa gttcgtgagc gtgcagtcgg gcatgaggtc attgatacac ttaatcctgc
     7741 gcaacagatt attaaaatcg ttgatgagga actgacagcc gttttaggtt ctgatacggc
     7801 agaaattatc aagtcaccta agattccaac catcatcatg atggttggtt tacaaggggc
     7861 tggtaaaaca acctttgctg gtaaattggc caacaaactc aagaaagaag aaaatgctcg
     7921 tcctttgatg attgcggcgg atatttatcg tccagctgcc attgaccagc ttaagacctt
     7981 gggacaacag attgatgtgc ctgtctttgc acttggaaca gaagtaccag ctgttgagat
     8041 tgtacgtcaa ggtttggagc aagcccaaac taatcataac gactatgtct tgattgatac
     8101 tgcgggtcgt ttgcagattg atgagctcct catgaatgag cttcgtgatg tgaaagtatt
     8161 ggctcaacca aatgaaatct tgcttgtcgt tgatgctatg attggtcagg aagcagccaa
     8221 tgttgcgcgt gagtttaatg ctcagttgga agtgactggg gtcatcctta ccaagattga
     8281 tggtgatact cgtggtggtg ctgctctgtc tgttcgtcac atcactggaa aaccaatcaa
     8341 gttcactggt acaggtgaaa aaattacaga tatcgaaacc ttccacccag accgtatgtc
     8401 tagccgtatc cttggcatgg gggatatgct cactttgatt gagaaagctt ctcaggaata
     8461 cgatgaacaa aaagcccttg aaatggctga gaagatgcgc gaaaacacct ttgattttaa
     8521 tgatttcatc gatcaattag atcaggtgca aaatatgggg ccgatggaag acttgctcaa
     8581 gatgattcca ggtatggcca acaatccagc acttcaaaac atgaaggtgg atgaacgcca
     8641 gattgctcgt aaacgtgcca ttgtgtcttc gatgacatct gaagaacgtg aaaacccaga
     8701 tttgttaaat ccaagccgtc gccgtcgtat tgctgctggt tctggaaata cattcgtcga
     8761 agtcaataaa ttcatcaagg actttaacca ggctaaacag ctcatgcagg gtgttatgtc
     8821 tggggatatg aataaaatga tgaagcaaat ggggattaat ccaaataacc ttcctaaaaa
     8881 tatgccaaat atgggaggaa tggatatgtc tgcccttgaa ggaatgatgg gacaaggcgg
     8941 tatgcctgac ttatcagctc tcggaggagc aggaatgcca gatatgagcc agatgtttgg
     9001 tggcggtttg aaaggtaaaa ttggtgaatt tgccatgaaa cagtccatga aacgtatggc
     9061 taacaaaatg aagaaagcga agaagaaacg caagtaagac aagagattga tgcaaatctc
     9121 atttgatgag aaaataaagt aaaaatttct atgataaaac gtacagtatc aaggttttag
     9181 aatatctgat attatacgtt ttttgatttt aataattttg ttaagacact tttattatgg
     9241 tatacgaaaa atccactcag ctgtctgagt ggattaggtg tatttagact cttagtcttt
     9301 attttcgtat ggcaagatca agttcaagat gattcctgtc atggctgaaa gggcagtacc
     9361 tgaaagtgta actggaccaa gtttaaggat agctcctcca agtccaagaa ccaacatagc
     9421 acttgcgatg atgaggtttc gcatttgagc gaaatcaaca cgttctttaa tcaagacttt
     9481 caaaccattg ctggcgataa ccccatagag aaggattgac ataccaccaa gtacagcgtt
     9541 tggaatagtt gaaatcaagg cagtgaattt accaaggaag ctgagggcaa tcgcgatgaa
     9601 ggcagcgtta cggataactg agacagaagc gatacgagtc ataccgataa cccctgtatt
     9661 ttctccgtaa gttgtattgg ctggtccacc aaggaaggca gaaacagaag ttgcgatacc
     9721 gtcaccaata agagtacggt gaagacctgg ttcttttaag aattgacggc cacagatttg
     9781 acccaaaaca gtatggtctc cgatatgttc agaaattgtt acgatagcga ttggcaagat
     9841 agcgatggct tctggaccaa agtaaagatt gtactcttta aaggcaccac ctgtgctaaa
     9901 tggcaagtag aaaccaggaa tttcgaacca gttggcttta agaactggtg taaagtcaac
     9961 caagccaaga gttagtgcga aaaggtaacc accgataatg gcaaagagga atggaatgat
    10021 tcgtaggaag ccttttcctt ttgtattgat aaaggcagca attaggaaag taacaacggc
    10081 taccagagca tttttccaat ttccgtctgc tacaagacct gcattggtaa cagctgaacc
    10141 tgcaagtcca agaccgataa cgatgatcat aggaccgata atgattggtg gcaagagttt
    10201 atcaatccat tttgttccta caaatcggat gctggtagca acaaggacat agaccaaacc
    10261 agtcaagata acccctgttt gggcagcaga tacatccccc cccatttctt tcatagccag
    10321 tgacatagct gtgataaagg caaatgaaga acctagataa actggaactt taaaaccagt
    10381 agcaatcatg tagatgagtg ttccaacacc tgaagcaaag agggcaacag atacaggcat
    10441 tcccaaaatc aatggtacca agatggtcgc accaaacatg gcgaaaacgt gttggaagct
    10501 aaggagaatt ccttttccat ccgaaggacg ttggtcaacg tctagtaaca aatcaacagt
    10561 tgattcttgt ttcatataaa cctcactttt gggcatcaga aaagagccca ttattttaca
    10621 gcaataggcc ctcagagtaa gacttctcta aaatctagac tttaaagagt ttcaaatatt
    10681 tttgcgtctt cgtcacctca cgggatgaca ttaaaaacct ttgcttagga tagtatagca
    10741 gaaaaaaatg attttgtaaa tcattttttc ccgagcctag aaataaaaga gcgaggctga
    10801 ttttgtaaac atttgtttac taaaaaattt aaagtgggcg tttatttggc ataccagcct
    10861 tacgtggata tttatttggt gtttcttttt tcttttctac cactgtgata tagcgcggat
    10921 ctctattcgg tagggcgtag ctgagattgt cttcgacctt actaaaaagg agattgaggg
    10981 cattcttagc ttctaataat tcctcaggcg cattgctggc cttgagtgcc aatagtttgc
    11041 caccaacctt aaggtaggga atagtcaatt cagataggac ctgcatacgg gcaaccgcac
    11101 gagctgttac aaaatcatat tgagcacgga agttcttgtc ttgggcaaaa tcttcggcac
    11161 gtccgtggta gaaatgaact ccgttcaaat ccagttcttg agccaagagt tgtaggaagt
    11221 tgatgcgctt attgagtgaa tcaataatgg tcacatctaa ctccggatag agaattttca
    11281 ttggtagact aggaaatcct gccccagccc cgatatcaag aagtttgata gtttcattgg
    11341 gaatcaaacc ttgaagaatg ggtgcaatcg aatcgtaaaa atgtttgaga taaacttctt
    11401 ccttgtccgt aatcgccgtc aaattaatct tctcattcca ctcgaccaag agctcaaaat
    11461 aacgttcaaa ttgttctttt tgctggttcg aaagtggaag attttgctcg gcaagcaagt
    11521 tgtaaaatgt ttctggtttc atagttattt ccttctttag tatcatctta ttttaccaca
    11581 atcattaaaa atttgatata ctggtactaa tctaaaagta gaaaggactt atatcatgac
    11641 ttggattatt cttggagtta tcgctcttat tgttgttttt gtgattgtta gctataacgg
    11701 tttggttaaa aatcgtatgc aaaccaagga ggcttggagt cagattgatg ttcagttgaa
    11761 acgtcgaaat gacctcttgc caaacttgat tgagactgta aaaggttatg ccaaatatga
    11821 aggttctacc cttgaaaagg tggcagaact acgtaaccaa gtggcggcag cgacttcacc
    11881 agcagaagct atgaaagcca gtgatgccct cactcgtcag gtttcaggta tttttgcagt
    11941 tgcagaaagc tatccagatt tgaaagctag tgctaacttt gttaaattgc aagaggagtt
    12001 gacaaataca gaaaataaaa tttcttactc tcgtcaactc tataacagtg ttgtcagcaa
    12061 ctacaatgta aaattagaaa ctttcccgag caatattatc gctggaatgt ttggatttaa
    12121 agcggcagat ttccttcaaa cacctgaaga ggaaaagtcg gttcctaaag ttgattttag
    12181 cggtttaggt gactaagatg ttgtttgatc aaattgcaag caataaacga aaaacctgga
    12241 ttttgttgct ggtatttttc ctactcttag ctcttgttgg ttatgcggtt ggttatctct
    12301 ttataagatc tggacttggt ggtttggtta tcgcactgat tatcggcttt atctacgctt
    12361 tgtctatgat ttttcaatcg acagagattg tcatgtccat gaatggagcg cgtgaggtgg
    12421 atgagcaaac ggcaccagac ctctaccatg tagtggaaga tatggctctg gtcgctcaga
    12481 ttcctatgcc ccgtattttc atcattgatg atccagcctt aaatgccttt gcgacaggtt
    12541 ctaatcctca aaatgcggct gttgctgcga cttcaggtct actagctatc atgaatcgtg
    12601 aagaactaga agctgttatg ggacatgaag tcagtcatat tcgtaattat gatatccgta
    12661 tttcgactat tgcagttgcc cttgctagtg ctatcaccat gctttctagt atggcaggtc
    12721 gtatgatgtg gtggggtgga gcaggtcgca gacgaagtga tgatgaccga gatggaaatg
    12781 gtcttgaaat cattatgcta gtggtttccc tactagctat tgtactggca cctctcgctg
    12841 caaccttggt tcagctcgct atttctcgtc agagggaatt tctggcagat gcatctagtg
    12901 tcgagctgac tcgcaatccc cagggaatga ttaatgccct agataagttg gacaatagca
    12961 aacctatgag tcgccacgtc gatgatgcta gcagtgccct ttatatcaat gctcccaaga
    13021 aaggtggggg ggtccaaaaa ctcttttata cccacccacc tatctcagaa cggattgaac
    13081 gtttaaaaca gatgtaaaat gaaggctgga aaaaagtctt taaaatctga aaaatgcata
    13141 atatcaggtg tgaaaacttg atattatgcg ttttactatg ggaagattta cttctttttc
    13201 tcctaaaatt gtgtttttgc cccacctatc tgctatgttg caaatttata aatcttctaa
    13261 attaactagc ttcaaaccgt gttctgtcat gcgacagatg atcgagcaga cttcttttaa
    13321 gaaacgacgg tcatgcgaaa cagtgatgag accgcctgga taggttgcaa agagttttct
    13381 gatttggggt tgagaagtgg gagaaaagtt tcgtgtgggt tcatccagca ggagaaagtt
    13441 tggtttgcgc aggactagat ccaaaagcag gagttttccc tgttgtccgc cagataagga
    13501 gcgaatttga tgctgcattt ctggataact gaaattgaga ctggctaggt gagattgaat
    13561 tttctgaagt tcctcttttt ccccagtttt gctgatataa gctattggtg ataaatccaa
    13621 ttgtagtttt ttgtggtaat cttgtggcat aaaaccaagg gaaatctctc ttttatcatt
    13681 cagaagttgc tttaatttgg ctaacagagt tgatttccca acaccatttg gcccgataat
    13741 accgattttt tcttgcccac ggacagttag ttgtagtttt tgaaccaaaa ctcggtcgtc
    13801 aatggacaaa ttttcttttt ccagttggac taagacttta gaagctggta atggttggat
    13861 atctgaaaag aaaagttgga tttgttcctc ttcaagtggt ttttgagtca tggactgagc
    13921 tgccttttcg tagcgttttt cttgtgagag gacagttttc atctttttag ccaataggcg
    13981 accggcagta ctatctttgg tagctcgaag cgcagtttct acattttgct taactctccg
    14041 atgtttttcc atggttttat cgtaggctct ttggttgtta gcagcttgct gactttgttt
    14101 ggcaaaatta gcctttctct gctcactata gctatcatag tctaaatgct ctactagcgt
    14161 ttccgcttct ttacggtgtt tgaccagtcg caagtgaaca atagtgtctg ccgtttcaga
    14221 aagaaagtct tcatcatggg aaatgaaaat aacggtttgc ctggtctttt gaatctggcc
    14281 ttttagccaa tcaactgtct caaggtctag gtcatttgaa ggttcatcta aaaatagaat
    14341 ctcaaagggt ttggctaact catggataag ctgaattttc aaagcttctc cccctgatag
    14401 attgccaatc tcttggtcac ttgcgaaacg attgctatca aaatgcaatt cctccgccaa
    14461 acgatagagg atactgtagt ctaaatcaat agaatctaaa aagaagtagt cgtgtaaagt
    14521 tttctttttc agctcctcgg gaagtttttg aggaatgtag gccagtgact gatagtcaga
    14581 ttggatgttt cccttgatag tgaaatcaga caaagcttcc cccattaaaa ttttaagtaa
    14641 ggttgatttg ccatttcctt cttcaccaat aatagcaacc ttttccccgt cttggatggt
    14701 catgcttagg tcagatacaa gatctcgtaa atctttgttt tgtgtgatgg ttagatgatt
    14761 gatttttatc atatgatttc cctttctaga atgttcatag tgcataacaa aaagctctac
    14821 tttacctagt agagcccaaa gtctatgtca aaaaaactct attaacatgc cagaaaaaga
    14881 gcataaaaga gcacacaaaa agagacaaaa acaagatcta ctaaataaag gttctttatt
    14941 tgatagactt agttgttcat gtctccctta cctccgagta ttagtatctt tatattatac
    15001 ctttaaggaa attttgtcaa cagaaaactg gaaattctat gctctaaaat tcaaaaacag
    15061 gtctatagag acttagtacg tgtttgacat gctcgtaatg gaatttatca tagtttcgcc
    15121 aagcagtgcg tgcttgatcg tttagtttta ggctacccag tccaatcaga agactggtgg
    15181 gttggtaaaa tttctcaaga tcaattaaga tactgttgtt caactgttcc gtttttttga
    15241 gctcttgcat agtagtgttt agcagctctt gtagtcgaat atcatctgcc gtaccctgtt
    15301 tacagttttg gtagctttta tttaacttgg ataggagttg aatgagtttc ttgtcttcca
    15361 tgtgagcatc ctccttgatc tgatgtactc tttccctata gtatagcact aaaaaacaaa
    15421 actgtcatag taaatatgtt aaagttttga attttaatta caaagtttgg tgtgctgatt
    15481 tgtagccttt tcatggtata atcaagagag taaatcttta tggaggaagt atgaaattaa
    15541 atattcaaga aattcgtaag cagtctgaag gtttgaactt tgaacaaacg ttagatttag
    15601 ttgatgacct gcgtgcacgt aatcaagaaa ttttagatgt aaaagatatc cttgcagttg
    15661 ggaaagtaca atatgaagac cgtatgtatt tcttagatta tcaactatct tataccattg
    15721 ttcttgcttc gagtcgcagt atggagccag ttgagttagt tgaatcttat ccagtcacgg
    15781 aagttttcat ggaaggcgca actaaccagc tagatcaaga agttttagat gatgacttgg
    15841 tcttgcccat cgaaaatggg gagcttgacc ttgctgagag tgtatcagac aatatcctgc
    15901 taaacattcc tatcaaggtc ttgacggctg aagaagaagc tggtcaagga tttatctcag
    15961 gaaatgactg gcaaatcatg acagaggaag aataccaagc tcaaaaagca gtaaagaaag
    16021 aagaaaacag tccttttgct ggcttacaag gactatttga cggagatgaa taatgatctt
    16081 gtcaaaaaaa cgagcacgaa aggtgctaga agaaatcatt gccctcttcc cagatgccaa
    16141 gcctagtctt gattttacca atcattttga actcctggtt gcggtcatgt tatcagccca
    16201 gacgacagat gcagcggtaa ataaggccac accaggtctc tttgttgtct ttccaacacc
    16261 ccaagctatg tctgtagcga cagagagtga gattgcttca catatttctc gcttgggatt
    16321 gtatcggaat aaagctaaat tccttaaaaa atgtgcccaa cagttactag acgattttga
    16381 tggtcaagtc cctcagacac gtgaagaatt ggagagtttg gcaggtgttg gtcgcaagac
    16441 agccaatgtt gtcatgagtg taggatttgg gattccagcc tttgcagtgg atactcatgt
    16501 ggagcgtatt tgcaaacacc acgatattgt caaaaaatca gcgacgccac ttgaggtgga
    16561 aaagcgggtc atggatatct tgccgcctga gcagtggtta gctgcccatc aggccatgat
    16621 ttattttgga agagccattt gccatccaaa aaatccagag tgtgaccagt acccacaatt
    16681 atatgatttt agcaatttgt aagatgctac attgaaactt tttgcttgat tttaagcatg
    16741 ctttgtgcta tagtaaatga taactaaata ttcctttaaa cctgtcccgt gaggcaggca
    16801 aggagcgcga taaagtagaa gggtgaagtc tatactgtgt gcagtagggc tcgcttggct
    16861 ataaatttca agtctccttg tttaaggaga cttttctttt tggaggtttg tcatgaaaac
    16921 aaaagaagtt gtagacgaat tgaccgtcaa acgagcgatt acgcgtatta cttatgagat
    16981 tatcgaacgc aacaaagatt tgaataagat cgtcttggct ggtattaaaa ctcgtggtgt
    17041 ctttattgcc caccgaatcc aagaacgttt gaagcagtta gaaaatcttt cagttcctgt
    17101 tgtggaattg gatactaaac ctttccgtga tgatgttaaa agtggagaag atacttcttt
    17161 ggtttctgtc gatgtgacag accgcgaagt tatcttggtg gatgatgtgc tctatacagg
    17221 tcgtaccatc cgtgctgcta ttgataatat tgtcggtcat ggtcgtcctg cgcgtgtgag
    17281 tttagcagtt ctagtcgatc gtggacatag agaattgcca atccgtccag attacgttgg
    17341 aaaaaatatc ccaaccagtc gttctgaaga aatcatcgta gagatgacag aacttgatga
    17401 ccaagacaga gttctgatta ctgaagaagc ttagaaagtt aaaggagtag ccatgtcaga
    17461 aaatcaacaa gcattgaacc atgtggtgtc catggaagac ctcactgttg atcaagtaat
    17521 gaaattgatc aagcgaggaa ttgagtttaa aaatggagcc cagattccct atgaagacca
    17581 tccgattgtt tccaatctct tctttgagga ttctacacgg acacataagt cctttgaagt
    17641 cgcagagatt aaacttggat tggaacgact tgactttgat gtgaagacta gttcggttaa
    17701 taagggtgag acactttatg acaccatttt gactctgtct gctttaggag tggatgtctg
    17761 tgtgattcgc catccagagg tcgactacta tagagaattg attgctagtc caacgattac
    17821 gacttccatc atcaatggtg gagatggttc tggccaacac cctagccaga gcttgcttga
    17881 tttgatgacc atttatgagg aatttggcca ctttgagggt cttaaagttg ctattgcagg
    17941 tgacttggac cactcacgcg ttgccaaatc caatatgcag attttgaaac gcttgggagc
    18001 tgaactcttt ttctctggac ctgaggaatg gagaagtcaa gagtttgcag actatggaca
    18061 gtttgtaacc attgatgaaa tcattgatca ggttgatgtc atgatgtttc tccgtgtgca
    18121 acacgaacgc catgatagtg gagctgtatt ttcaaaagaa gactaccatg cccaacatgg
    18181 cttgactcaa gaacgttacg atcgtttgaa agaaacagca atcctcatgc acccagctcc
    18241 aatcaatcgt gatgtagaaa tagcagacca cttggttgaa gcaccaaaat cacggattgt
    18301 ccaacaaatg accaatggtg tctttgttcg aatggcaatc ttagaatccg tactagcgag
    18361 tagaaacgcc aactaaaaca caagacgtta aaagacgcca gtgagcgtcc acgagaggtg
    18421 aaaatatgac aaaaagaatt ctagtattag aagatggcac agtttttgaa ggcaaggcct
    18481 tcggagcaga tattgatgta acaggcgaaa tcgtctttaa tacagggatg accggctacc
    18541 aagaatccat tacagaccag tcttataatg gacaaatctt gacctttact tatcctttgg
    18601 taggaaatta tggtattaat cgtgatgatt atgaatccat tattccaact tgtaagggag
    18661 tcgttgtttt tgaagaagcg cgtagagcta gcaactggcg caaccaaatg accttggatg
    18721 aatttttgaa agccaagaaa attccaggga tttcaggaat tgatacgcgt gctcttacca
    18781 agattatccg taagcatggt actatgcgtg caaccttgac ccatgttggg gacagtatgg
    18841 accatgtgac ggaccagctc caagcaacag ttttaccgac agacaatatc aaacaggttt
    18901 ctactaaaac gtcttatcca gctccaggag ttggtttgag cgtggtgcta gtggactttg
    18961 gtctcaagca ctcaatccta cgtgaacttt ctaaacgcaa ctgtaacgtg acagttgttc
    19021 cttattcgac aacggctgaa gaaattctcc atctcaatcc tgacggagtt atgttgtcaa
    19081 atggtccagg taacccagaa gacgttccac aagcactcga catgattcgc ggtgtacaag
    19141 gaaaaattcc aatctttggt atttgtatgg gacaccaact ctttgcaatg gcaaacgggg
    19201 ctaagaccta taagatgaag tttggccacc gtggattcaa ccatgcggta cgtgaaatcg
    19261 caacaggacg agtagacttc accagccaga accatggtta tgcagtcagc cgcgaggatt
    19321 tgccagagca cttgattatt acccacgaag aaatcaatga caagtcagtg gaaggtgtgc
    19381 gccacagata ccaacctgct ttctctgttc aataccaccc agatgcagct cctgggccac
    19441 acgacgctag ctacttattt gacgagttta tcgagatgat ggaagttttt aaacaatcaa
    19501 actaagaacg agtaaaagct cgtcggagaa tttatgtaac tgaacacgga cggaaagctc
    19561 agaatttaga gaaaccaact tggattgtca atccttcctt gatttcctaa aaatcaatcg
    19621 ctttctattc gtcctttgta tcttatttaa tgtcgccctg agaggctacg aatagaaagg
    19681 agaagggtgc tccgtatttg ctgaactgaa tacgggctac ggacggtgct aaaaagatag
    19741 ttattcctag aactgacagt tcttcgtcat aactcctatt ttagctttgt ccgcttgacg
    19801 cccttaatat cttatatatg cctaaacgta ctgatattca aaaaattatg gtgattggtt
    19861 ctggtccgat tattattggt caggctgctg agtttgacta cgctgggacc caggcttgct
    19921 tgtcgttgaa agaggaaggt tatgaggttg ttttggttaa ctcaaatcct gcaaccatca
    19981 tgacggacaa ggaaattgct gataaggttt acattgaacc gattacactt gagtttgtga
    20041 cacgtattct tcgtaaggaa cgtccagatg ccttgctacc aacactcggt ggtcagacag
    20101 gtctcaacat ggccatggaa ttgtctaaaa atggtatctt agatgagctt agcgttgaac
    20161 ttctgggtac taaattgtct gccattgacc aagcggagga ccgtgacctc tttaaacaat
    20221 tgatggaaga gcttgagcaa cccattccag aatctgaaat tgttaacaca gtagaagaag
    20281 cagttgcctt tgcagcgaca attggctacc cagtcatcgt tcgtccagcc tttacccttg
    20341 gtggtactgg tggtggtatg tgtgccaacg agaaagaatt gcgtgaaatc actgaaaatg
    20401 gtttgaaatt gtcacctgtt acccaatgtt tgattgagcg ttcgattgcc ggtttcaagg
    20461 aaattgaata cgaagtgatg cgtgactcag ctgacaatgc cttggttgtt tgtaacatgg
    20521 aaaactttga cccagttggg attcacacag gggattccat tgtatttgcc cctgcgcaaa
    20581 ccatgtcaga ctatgaaaac caaatgcttc gtgatgcgag cttgagcatt attcgtgccc
    20641 tcaagattga aggtggatgt aatgttcagc tagctcttga tcctaacagc ttcaagtatt
    20701 atgttatcga agtaaaccct cgtgtatcac gttcgtcagc ccttgcttct aaagcgacag
    20761 gatatccgat tgctaagttg gctgccaaga ttgcagtagg tttgaccttg gatgaggtta
    20821 taaacccagt tacaggttca acctatgcca tgtttgaacc agcccttgac tacgtagttg
    20881 ctaagattcc acgtttccca tttgacaagt ttgaaaaggg tgaacgccgt ctcggtacac
    20941 aaatgaaggc gactggagaa gtcatggcaa tcggtcgtaa catcgaggaa tctcttctca
    21001 aggcctgccg ctcccttgaa attggggtgc accacaatga aatacctgaa cttgcagtag
    21061 tttctgatga tgccttgatt gaaaaggttg tcaaagccca agatgaccgt ctcttctacg
    21121 tatcagaagc aattcgtcgt ggctacacac ctgaagaaat tgcagagctt acaaaaattg
    21181 atatcttcta tcttgataaa ctcttgcata tctttgaaat tgagcaagaa ttgggtgctc
    21241 atccacaaga tctagaagtt ttgaaaacag ccaaacttaa tggtttttca gaccgtaaga
    21301 ttgctgaact ctggggaacg actgatgata aagttcgcca acttcgcttg gaaaacaaga
    21361 ttgttccagt ttataagatg gtagacacat gtgcggcaga gttcgactcc gaaacgccat
    21421 atttctattc aacctatggt tgggaaaatg aatctatcag atctgataaa gaatctgtac
    21481 ttgtcctagg ttcaggtcca atccgtatcg gtcaaggggt tgagtttgac tacgcaaccg
    21541 ttcactctgt taaggctatc caggcagctg gttatgaagc tatcatcatg aactcaaacc
    21601 cagagaccgt ttcaacagac ttctctgtat cagataagct ttactttgag ccattgacat
    21661 tcgaagatgt tatgaacgtc attgacttgg aacaaccaaa gggagttatc gttcagttcg
    21721 gtggtcaaac agccatcaac cttgcggagc cattggcaaa agcaggtgtg accatccttg
    21781 gtacacaggt tgctgaccta gaccgtgccg aagaccgtga cctcttcgag caagctctca
    21841 aagaattgga tattccacag ccaccaggac aaacggctac caatgaagaa gaagcagctc
    21901 ttgcagctcg taagattggc ttcccagttc ttgtccgccc atcttatgta cttggtggac
    21961 gtgccatgga aatcgttgaa aacgaagaag atcttcgttc ttacatgcga actgctgtta
    22021 aggctagtcc agaccaccca gttcttgtcg actcttatat cgttgggcaa gagtgcgaag
    22081 ttgatgccat ttcagatggt aaaaatgtac tcattcctgg tatcatggag catatcgaac
    22141 gtgctggtgt ccactcaggt gactcaatgg ctgtttaccc accacaaacc ttgtcgcaaa
    22201 aggttcagga gaccatcgca gactacacca aacgcttagc aatcggtctt cactgccttg
    22261 gaatgatgaa catccagttt gttatcaagg atgaaaaagt ctacgttatt gaggtcaatc
    22321 cacgtgccag ccgtaccgtt ccattcctat ctaaggtaac caatattcct atggctcaag
    22381 tagcgaccaa gctcattctt ggtcaaagtt tatcagaact tggctaccaa aatggacttt
    22441 accctgaaag cacccgtgtt catatcaagg cacctgtctt ctcctttacc aaactagcta
    22501 aggtagacag cttgctcggt cctgaaatga agtcaacagg tgaagttatg ggttctgatg
    22561 ctactttgga aaaagctctc tataaagcct ttgaagcttc ttatctacac ttgccaactt
    22621 ttggtaatgt cgtctttacc atcgctgatg atgccaaaga agaagccttg aacttggctc
    22681 gtcgtttcca aaacattggt tatggaatcc ttgcgacaga agggacagca gccttctttg
    22741 ctagtcatgg cttgcaagcc caacctgttg gtaagattgg tgatgacgat aaggatatcc
    22801 caagttttgt acgcaaagga agaattcaag ctatcattaa cacagtagga acaaaacgaa
    22861 ctgctgacga agatggtgag caaattcgtc gttcagccat tgaacacggg gtgcccctct
    22921 tcacagcgct agatacagct aatgccatgc ttaaggtact tgaaagtcgt agctttgtta
    22981 cagaagcgat ttaaatagaa aaataag
//
LOCUS       DAVKMO010000028        22846 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVKMO010000028 DAVKMO010000000
VERSION     DAVKMO010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.028"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(120..1100)
                     /locus_tag="VW361_001270"
     CDS             complement(120..1100)
                     /locus_tag="VW361_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU9744307.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFYDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            complement(1416..3431)
                     /gene="recG"
                     /locus_tag="VW361_001271"
     CDS             complement(1416..3431)
                     /gene="recG"
                     /locus_tag="VW361_001271"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU9744308.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3450..4553)
                     /locus_tag="VW361_001272"
     CDS             complement(3450..4553)
                     /locus_tag="VW361_001272"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU9744309.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4543..4911)
                     /locus_tag="VW361_001273"
     CDS             complement(4543..4911)
                     /locus_tag="VW361_001273"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU9744310.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(4950..5981)
                     /locus_tag="VW361_001274"
     CDS             complement(4950..5981)
                     /locus_tag="VW361_001274"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9744311.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(5983..7014)
                     /locus_tag="VW361_001275"
     CDS             complement(5983..7014)
                     /locus_tag="VW361_001275"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9744312.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7095..9608)
                     /gene="secA"
                     /locus_tag="VW361_001276"
     CDS             complement(7095..9608)
                     /gene="secA"
                     /locus_tag="VW361_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU9744313.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQAMIKRTIGRVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9754..10041)
                     /locus_tag="VW361_001277"
     CDS             complement(9754..10041)
                     /locus_tag="VW361_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744314.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWIAFFFLPWGSPILGGKIDLFS
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFILFAILPILGN"
     gene            complement(10052..10702)
                     /locus_tag="VW361_001278"
     CDS             complement(10052..10702)
                     /locus_tag="VW361_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9744315.1"
                     /translation="MKLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKVLAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            complement(10706..11347)
                     /locus_tag="VW361_001279"
     CDS             complement(10706..11347)
                     /locus_tag="VW361_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744316.1"
                     /translation="MFKNFNNILLKRKIVLLLRIVLMMILINHLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEVNLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLLVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLLLLSLLVMLIVSRLEEKFKKG"
     gene            complement(11340..12131)
                     /locus_tag="VW361_001280"
     CDS             complement(11340..12131)
                     /locus_tag="VW361_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744317.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIVTYFFGTFSPLGWNSLFSDGSSLQR
                     LLDGEITSYLFFTCVLLIGIFINAVYFFKIVDYLGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYIVPYMVLEKYEDNV"
     gene            complement(12316..12651)
                     /locus_tag="VW361_001281"
     CDS             complement(12316..12651)
                     /locus_tag="VW361_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744318.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     SLFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(12791..13126)
                     /locus_tag="VW361_001282"
     CDS             complement(12791..13126)
                     /locus_tag="VW361_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744319.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13217..14527)
                     /gene="der"
                     /locus_tag="VW361_001283"
     CDS             complement(13217..14527)
                     /gene="der"
                     /locus_tag="VW361_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU9744320.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRR"
     gene            complement(14541..15254)
                     /locus_tag="VW361_001284"
     CDS             complement(14541..15254)
                     /locus_tag="VW361_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU9744321.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            complement(15251..16147)
                     /gene="dnaI"
                     /locus_tag="VW361_001285"
     CDS             complement(15251..16147)
                     /gene="dnaI"
                     /locus_tag="VW361_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU9744322.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKFSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16148..17317)
                     /locus_tag="VW361_001286"
     CDS             complement(16148..17317)
                     /locus_tag="VW361_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU9744323.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17318..17791)
                     /gene="nrdR"
                     /locus_tag="VW361_001287"
     CDS             complement(17318..17791)
                     /gene="nrdR"
                     /locus_tag="VW361_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU9744324.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            17931..18296
                     /locus_tag="VW361_001288"
     CDS             17931..18296
                     /locus_tag="VW361_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9744325.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18301..18996
                     /locus_tag="VW361_001289"
     CDS             18301..18996
                     /locus_tag="VW361_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744326.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19013..19780
                     /locus_tag="VW361_001290"
     CDS             19013..19780
                     /locus_tag="VW361_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744327.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20133..21332)
                     /locus_tag="VW361_001291"
     CDS             complement(20133..21332)
                     /locus_tag="VW361_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9744328.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMTKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAEGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(21329..22222)
                     /locus_tag="VW361_001292"
     CDS             complement(21329..22222)
                     /locus_tag="VW361_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744329.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22338..22418
                     /locus_tag="VW361_001293"
                     /pseudo
     CDS             22338..22418
                     /locus_tag="VW361_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
BASE COUNT         6722 a         5134 c         4243 g         6747 t
ORIGIN      
        1 cctgttcttg tttcatttta ctatatttct atgataaaac gcatagtatc aagttttctt
       61 aatcccctga tactatgcgt gtttgtaatt tttaagattt tgtgcttaga gtcgactcct
      121 tattttagat atttaaaagg aatctcactt ccacagagcc agttgtagac ttggtcatta
      181 acaaatacat tcatggcttc gtgagcatac tcaggcatga tacgataggt tttatcgcag
      241 gtcagacgat tataaatcgc aaactgggta atgggatagc aaacatcgtc gtccaagccc
      301 gtaatcatct taacctcacc ttggatacga tgggcaagat ttttgacatc gatataggca
      361 agggtcgcca tgatttcctc ctctgtttca tggaaggggt cgtaaaactt gaaataacgg
      421 aaaagttcgt cgtaagcctc gctagtatta ccaatctcaa tcacccgtct gaagtctgac
      481 aagaagggat aaatggcaac tgttttctga attcgaggat tgagcgctgc tgcaactagg
      541 gctagagccc ctccttgtga ggcaccatag ctagaaagac gcttctcatc aacctgagac
      601 agactagcaa caatttcgac caactggtaa atatccagat aaacatcctt ataaaagagg
      661 tggtcccgac cttccacagc accacggata atatgcccct tcacggtatt tcctaaagga
      721 gaacgcaagc cgtcttgtga gtaacctgac tggccccgca catccatgga aacaacaccg
      781 taaccagcta cggtgaagcc cagcatgtcg gcccagtccc agccacgtcc catataacca
      841 tgaaaatgga agattaatgg aaccttctcc tcactctttg gaagaacaat gcgtgcatag
      901 acctttcctt ccttgcttcc ttcaaatgtt aactcatagc acttgacttg aggaatgtgg
      961 aaatctcttt cctccaagtg gtaggatgga agcgtggaaa catttttcac ttccccatcc
     1021 cagaaagcat caaagtcttc cggaacctca tcccttcctc tataggtctt aatttcttct
     1081 agcaaagctg gatttttcat agcatgctcc ttttattttg taatcgttac cacaactgta
     1141 gcatatctat gtaatcaatg caagaaagaa ggataaatag aaagtgaatt tagattcttt
     1201 acttttagga tgatgggctg aaagtagttt tagaaacgaa aaagagcatt tcgctctctc
     1261 ttctgtttat actagttttt tgcttccttc ttttggaaag tggtttggta atttacttta
     1321 atcgttactg tcatatgaga gtcctcgttt ctttttgatg actttagtat aagagccaaa
     1381 cctaaaaact agcttaagtt ttccttagag aaagcttaat ccagatgttc tttcttttcc
     1441 agatgaaggg caatcatgcg ccactctgga tcttcttgcc aagcttctat agaactaatg
     1501 tagctagcaa cctttcttgc ttcttctaaa atcggaaaat cttcgataat atcagccact
     1561 tggaactctg gaagtcctga ctgtctggtt ccaaaaatct caccagaacc acgcattttc
     1621 aaatcttcct ccgcaaggac aaatccattg gtcgtttctg tcatgatacg catgcggtct
     1681 ttcccagaat ccgtcttggg attagcaacg agaacagcgt aggactgctt gtccccccga
     1741 ccgacacgac ctctaagctg gtgaagttga ctgagaccga agcgatcggc atccatgata
     1801 atcatgacag tcgcattggg aacgttgacc ccaacctcaa taaccgtcgt cgaaaccaga
     1861 atatccgtct ttctctcctt gaaatcctgc atgatctggt ctttttcgtc actcttcatc
     1921 ctaccatgta gaagagccac ctctgccttg cctgcaaaat gagtcgtcaa ctcctctgat
     1981 aaggcaatgg catttttcaa atctagagct tctgattctt caatcaaagg agagatgaca
     2041 tagacttggg aacctttttg aatttccccc tctaaccaag tcaagacctg aggtagttgc
     2101 tcatgtttga tccagcgcgt cacaataggc ttccgacctg ctggcatctg gtcgataatg
     2161 gaaacatcca tatctccaaa ggctgtgatg gcaagcgtcc gtggaatggg agtcgccgtc
     2221 atcatgagga catctggatt gtcacctttt tcccgtaaaa tacgcctttg ccctacacca
     2281 aaacggtgct gctcatcgat aataatcaaa ccaagacgag catactccac cccatcttgt
     2341 atcagagcgt gagttcctat aatcaaatca gcctcaccct tggcaatggt ctccaagact
     2401 tctctctttt ctgcagcttt caaggaacct gtcaagagag ccagtttcaa attgggaaaa
     2461 aggttctgta aactctcaaa gtgttgctct gcgaggattt ctgttggtac cattagggca
     2521 gcctgataac ctgctgtcac tgccgcaaac atggccaagc cagcgactac cgtttttcca
     2581 ctccccacat ccccttgtag gagacgattc atgtggtggt cggacttcat atcagttaaa
     2641 atttcctgca aactcttttc ctgagcttgg gtcagggcaa aaggaagact tactttaact
     2701 gctgtcactt tttcctgaga ccaattcaga accagaccac ttccctgaac tctattttca
     2761 gacttgagca tctgcagctg catttggaaa taaaagagtt cctcaaactt tatacggcga
     2821 agagcctgct tgtattctgc caaatacttt ggaaaatgca tagcacggac tgcctgacaa
     2881 cgggacatga gtttgtattt gtctagtaaa gactggggca gattttcttc tatcaagagg
     2941 tccagtccct gatcaaaagc cgtcttgatg accttgacca gactggcctg actgattccc
     3001 tgagccagac gatagacagg ctggaggtca tcttctacct gagccagaac cttcatccca
     3061 gtcagactag ccttagcgcg gtcccatttt ccaaagacag caagggttgc tcccaactct
     3121 attttatcag ccagataggg ctggttaaag aaattcaccg caaaaacgac ctctccctgc
     3181 ttgagactaa aacgcaggcg attgcgcttg aaaccataat actggacact agcaggagtc
     3241 actacctgac cagaaagaac tgccttctca ccgtcttcca gctccagcac ctgcttggtt
     3301 ttgaagtctt cataacggaa aggaaagtag agcaagagat cttgcaagtt ttcaattcct
     3361 agtttggcgt atttttctgc tgactttggt cccacaccag gcaagacatg caagggttga
     3421 tgtagattca tgctccactc ctttcttttc taataatatt ctctcggaat acggtcgctg
     3481 aggaggcaaa ccacctcata gttaatggtt acgcggtagg tcgctacctg agttgcagtg
     3541 atttccttat ccccattgga gccaatcaag gttaccttgg ttcctagcgg ataaagctta
     3601 ggcaatcgaa tagtgatttg gtccatcgaa accctgccga caattgggca agcttggcca
     3661 tctaccaaga cagagaaatt ttgcatgtct cttgtccatc catctgcata cccgattggc
     3721 acggtcgcga tgacttgctc gctatccgct tgataagttg ctccatagcc catgcaagct
     3781 ccagctggaa ctgtcttgac atgaaccaga gcagactcca aggtcaaggc cggtatcaaa
     3841 tcataaggca aatccaagac cgctccactt ggattgaggc catacatggc atctcccata
     3901 cgaaccgcat tgaaaatagt ctctacatgc caaagagtcg ttgcagaatt gctagcatga
     3961 accagctctg gaacttcctt catactagct aaaatagttt taaaccgttc taactgggca
     4021 ttaaaatagt catctgattc ctcatcagca gtagcaaagt gggtaaagat tccttcaaca
     4081 caaacaccgt gttgttggag caaatcttga gcctgctcaa cctcacttgc ctctctaaaa
     4141 ccaatccgtc ccatccctga atcaatcttg aggtggactg tcaatccagt taggtccact
     4201 tccttatcta agagtgcttg aatccactcc agtccagcca ctgtcaaggt gaagtcatat
     4261 tctttagcta gagcaacagc ttcgatttca gaaactccta aaatgaggat tggcttgctg
     4321 agtccagctt gtctgagttc aatggcttca tcgatattgg aaacgcaaaa gccatcaaca
     4381 tcatcttgaa ttgccttggc aacggcaaca gctccatgac cataagcatt ggccttaacc
     4441 acagccaact tgagcgttcc ttgagggata tgagccccca tttgctgaat attttgtcga
     4501 atagctccca gatgaatcag agccttggtt ggtctatgtg gactagcttt catgattttc
     4561 ctccaaaatg acactggctg tcacaaactg atcggtgtgg ctgatagaca gccaaatctt
     4621 tcctgaaaat ggtgcctgac taaaataagg cgccccacgt tcattgttca agacttccaa
     4681 atcctgaaaa ccgagcttgc taatgcccgt tcccatagcc ttggaaaagg cctccttagc
     4741 cgaccagcga ccagctaaat attctatttg cctgcgtcct ttgagactgg tgaagcgctc
     4801 catttcctga gcggtcagta cacgcttagc aaatccttca tgtcgtgtaa ctgcgctttc
     4861 tatcgaagcc aattcttcga tgtcaattcc gtgtccaact atcattctca tcaaaaggag
     4921 ttgagattcc ccaactccat ccttttcact tattttgtca aggtaacata aatctcttct
     4981 accaaggcct ctgtattttc ccaacctagg caagggtcag taatagagca accaaagatc
     5041 tctggttggt tttgacgacc atctgctagg taagattcaa tcataaatcc tcgaaccgtc
     5101 tttttaattt tctcattcca atcacgattc tgcaaggtct ggcgaacaat tcgaatctgc
     5161 tccatatatt gcttgcctga gttatcatgg ttggtgtcaa tgaggataaa aggattttca
     5221 agtcccatgg tttcatagcg ttcaatggct tggagtagat tttcatagta gtaattcggc
     5281 atataattgc catactcgtt gactgctcca cggaggataa catgggccaa aggattacct
     5341 gatgtctcaa cttcctgccc atgataaagg aaggtttgct tgttttgagc agcatagatg
     5401 gcgttaaaca taacacccaa atttcctgag gttggatttt tcatccctac tggtgcatca
     5461 atcccagaag ccacaaagcg gtgctcttgg tcttccacag aacgagctcc aacggcatgg
     5521 tagctgacca agtcatccac caagatcaga tttgacggat aaagcatctc atctgccgtt
     5581 gtcaaaccag tctctgtaat cacgcggtag tgcaactggc gcacagcctg caagccatta
     5641 atcaggcttg gagccttaga agtatctggc tggtgaacta atcctttata gccgtctcca
     5701 ttggtacgag gcttagcagt atacacgcgc atgaccatga aaatcttatc cgctaccttc
     5761 ttttgcaagg cagataaacg gcgagcatat tccaagaccg cctcttcatt atcagaagag
     5821 caaggaccaa tcaccaagag aatacggtca tcttcccctg aaataatatc tgccaattcc
     5881 ctgtcacggc tttccttgag tctcaaggct tccgcagaca attgggtttc agccttgatg
     5941 acttccatat cgatttcttg acctttttca ataaatgcca tcttattctc ctaacgtttt
     6001 gtaaatttct ctgacaagag cttctgtgtt atcccaaccc aggcaagggt ctgtgataga
     6061 cttaccaaat acttctggct cattttgtcg accatcttcc agataagact caatcataaa
     6121 accacgaacg aactgcttaa ttttttcatt ccaagcacgg ttaatcaagg tctggcggac
     6181 aattcggatc tgttcaatat actgcttacc agaattgtca tgattggtat caatgatgat
     6241 aaaaggattt tccaagccca ttttctcata ctgggcaatg gtatcaatta aattgtcata
     6301 atagtagttg ggaatatttt ttccatactc attaagagca ccacgaagaa tagcgtgtga
     6361 aagcgggttc ccagttgttt ctacttcttt tcctaagaaa aggaaacttt gtttgttttg
     6421 agcagcataa atcccattaa acatgacatt gagatttcca gaggttggat ttttaaaacc
     6481 agtagaaaat cctgccccac ttgccacaaa gcggtgttgc tggtcttcaa ctgaacgggc
     6541 accaactgcc atgtaagaaa tcaaatcatc tacaagcgga aggttttcag gataaagcat
     6601 ttcatcagca gttgtcatcc ctgtttctgt gatgacacga tagtgaagat ggcgaacggc
     6661 tttgattcca ttgataagac taggcgcttc tgtcgcgtta ggctggtgaa tcaagccctt
     6721 atagccatct ccgttggtac ggggtttggc agtataaaca cgcataacca taaagatacg
     6781 atctgccact tcttcttgta ggactgccaa acgcttagcg tattcaagga cagcttcttc
     6841 gttgtcagat gagcatggcc cgattaccaa gagaattcgc tggtcttctc cacgtataat
     6901 ggcttctagc tcttgatctc gctgtgattt cctctccaaa gcctgacctt ctaattttga
     6961 caaggcacga acttcttcta tatttatttt agagcttttt gctgtaaata ccataactca
     7021 tctccttata aagcaaacgg atacccagta aaaatttact tttcacaaga tatccgcctc
     7081 taaactatct cattttattg tcttttaccg tgacagtttt taaatttctt accagaacca
     7141 catgggcaaa gttcattgcg tccaatctgg ctcaaatcca aatcttctgg catacttgct
     7201 tggtgagcag cgatattgcg agtcgctgtt gtactgatat gacgttctgc ctgtggtctt
     7261 tcttgttcat gaatttgtgc tttcatcatc aagcgtgtca catcaaactc aatcgaacca
     7321 atcatatcat taaacatacg gaaaccttct gcctgatact caacaacagg gttgttctga
     7381 gcatagccac gaagtccaac cgcgttacgc aattgatcaa gggcatcgat atgatctgtc
     7441 cacttgttat ccaccactcg tagaatcaaa actttttgga attctttaac tgcttcttca
     7501 tcgcgtagtt ttgaaacctg actatcgtaa accttcaagg cacgttggaa aagctcttcc
     7561 ttgatggcct tatcagacaa gcctgacaag tcttccatcg taatagaatc ttcaggaagc
     7621 aagttatact tagcgaagtt caaaattgcc tctagtttct catcttgttt agcacgcgca
     7681 tgaccgtcaa cgacacgacc aatcgtgcgt ttgatcattg cctgaatttc aggtgccaag
     7741 tcacggtctg cagtaatgac atcataacgt tgagtataga taatctcacg ttgttcacgc
     7801 atgacatcgt cgtattgaag gacttgttta cgggtatcgt agttatttcc ttcgacacgt
     7861 ttctgagctg cttcaacctg acgcgtcaac atgcgagact caatcgcctc ttcagacatg
     7921 ttgagacgtt caaagattcc cttcaagcgt tcagaaccaa aacgtttcat caaatcatct
     7981 tcaagagata ggtagaattg tgactcacct ggatctcctt gacgacctga acgtccacga
     8041 agctggttat cgatacgacg actttcatga cgttctgtac caataacaca aagtcctcca
     8101 agttcacgaa caccttcacc aagcttgatg tcggtaccac gacccgccat gttggttgcg
     8161 atggtaacgg caccacgttg accagcattc atgatgattt gggcttctct atagtggttt
     8221 ttggcattca agacttcgtg aggaacacca gctgcaacca atttcttaga aatgtagtca
     8281 ctagtttcaa ccgctactgt accaaccaag acaggttgac ccttttggta acgagcctta
     8341 acgtcttcga caaccgcttt aaacttagat tcgatacttg cataaagaag gtctgagtgg
     8401 tcaatacgtt gaacaggacg gtttgttggg attggaataa cacgaatgtt gtagatttca
     8461 cggaattctt cttcctcagt cttacctgta cccgtcatac cagacaattt cttgtacata
     8521 cggaaaaggt tttggtacgt gattgaggca gatgtcttgg tttcatcctg gattggcaca
     8581 ccttctttgg cttcaatagc ttggtgcaat ccatcagaat aacgacgacc ttccatggta
     8641 cgacctgtaa attggtcgac aatcaagatt tcttgctctt cgctcaccac atagtcaata
     8701 tcgagaagca tgatgtagtt ggcacgaagg gcgttatcga taaagtgggt caaagccacg
     8761 ttttcgatgt catagaggtt ttcaagtttg aagtagcttt cagccctgtc aatccctgaa
     8821 tcagacaaac caatagtctt agactgcaca tcgatgatgt agtcatcttt gttcaaagat
     8881 tttacatagt ggtctgccat gtgatacaac tgactggttt caaccgcatt ggcacctgat
     8941 acaatcaaag gtgtacgagc ctcgtcaatc aagatagagt caacctcatc gaccaaggca
     9001 tagttaagcg gacgttgtac catgttttca gcgcgaacga ccatgttgtc acgaaggtag
     9061 tcaaatccga tttctgagtt agttgagtaa gtaatatcac actcataggc ttcttttttc
     9121 tccattggag atttggtagc caagttaatc cctactgaca aaccaagcca agagtacaat
     9181 tcacccatct cagtcgcgtc acgttctgac aggtattcat taaccgtaac tacgtgaacc
     9241 cctttacctg aaagggcatt gaggtatacc ggcatggtcg cagtcaaggt tttcccttcc
     9301 cctgtacgca tctctggcac gtcaccatgg tgaagaacaa tcccccccat gacctgaacc
     9361 ttataaggga agagacctag gacacgtttg gcaccttcac ggacaaccgc aaatgcttcg
     9421 taaagcaatg aatccagtga ttctccattt tgataacgtt ccttaaattc aactgttttt
     9481 gcttttagtt ggtcgtcagt caaagcagcc atttggtctt cgtatttgaa aaccttgtca
     9541 gccatctttt ccagacgacg gatttctcct ttatcatttt cgataattgt ttttaaaata
     9601 ttagccatgt ttttccttac tttaaattcc gaatatttta gaatgttcct ttaattttag
     9661 cacaattact gattattttc aaggaagaat ccccattttg aaaaggaaaa agaggttagt
     9721 ttccaagcta acctctctga cttttatgat actttaattg ccaagaatcg gcaaaatagc
     9781 aaataggata aataagttaa tccaaagaga aagacagcag atcaatccaa aaacaaagag
     9841 actgactttc ttggacagca aggccatcaa aatggacaga atgccaaaaa ctagcaagac
     9901 tttctgtatg ctgaagaggt caatcttccc ccccagaatc ggactgcccc aaggaagaaa
     9961 gaagaaagca atccagatca acagaactaa accaatataa accttggaat agcgtgtaat
    10021 aaatgatttt agatgtgcca taagccatct cctaggattg tatatccttt acatattgta
    10081 tatgtccatt ttcgacaact aatacatctg tacaaaggtc tgaaatatct tccgatatgt
    10141 gcgacgtcag gataaccaga ccattttctt ttttcaggta agataaaatg acctgtttgg
    10201 ttaacctcac actcttctca tccaaagcat tcataggttc atcgagaaag agtatagaag
    10261 gagaggaaat aaaggcttga atcaaggcca ttttttgctt tgttcccaag gataaatgcc
    10321 ggtattcaac gtcttcaaat tcctgtaaat catagtattg aatccaatag gcaattcttt
    10381 tttccgtaac tttagatgaa aaatacctta acagttccaa attttctctc agggataaat
    10441 gagataaaaa ctcgactttt tcaattaaaa ttcctgcatc ctgaatataa tgatttttta
    10501 tcccgtaaac tttaccatct tgaagaactt ttcctttgtc aagcttaata taaccagcaa
    10561 gtacctttaa aagaaccgtc ttgccagatc cattatcacc tttaagtcca taaatttttc
    10621 ctgattgaaa caccaaattc aactgattta aaataggtct tttcccataa attttctgtc
    10681 catttataat ttcaagtttc atcgtttatc ctttcttaaa tttctcttcc aagcgactaa
    10741 caatcaacat aactaataag cttaagagta gtaaatacac tgttacaata tgatccatca
    10801 tccattcttg tcccacaaat gctaaaaaat agagaaaaaa ggaaaaacca gcgcccgcac
    10861 taatcagtgc tatcagataa gacagtagta agtacaacat cattaactga gcaagtaaaa
    10921 agaaaagtgc gactgttttg aaatgaattc ctagcggaag taaaccaagg aaccagacaa
    10981 gtaaatcttg agtaaaaaat ttagaaatga caaccaatcg tttccttgta taatcgaaaa
    11041 aggagcttga ttgatagcga atcaagtgat ggtaatggtc tgccaaatca ctttcaagta
    11101 aaatgacaga gagccatcct accatgaaaa gcgaaaggtt taacaagagt ttggggattt
    11161 ctaaattcac ttcagaatag tcattatagg aaaaaattga aatcaattct ctcttgaaaa
    11221 agataacagc atcctgcttt tgaaccgctg ttgacaatag atggtttatc aaaatcatca
    11281 tcagaactat acgaagtagt aaaacaatct ttctctttag caaaatattg ttaaaattct
    11341 taaacattat cttcatattt ttcaagcacc atgtaaggga caatataaag gatataagga
    11401 gtaaagagtt tcatcaaact tacatcccca tagctagctt gcatcaaact cgtcatagga
    11461 accatatagt aaggcaaggc actatagagc agcatagaac caagccaaag aaacatcaaa
    11521 taggtgattg ccgaacgagt cacatttcct aaataatcaa ctattttaaa aaaatagact
    11581 gcattgatga aaataccgat tagtaggaca caagtaaaga acaaatagct tgttatctct
    11641 ccatctagga gcctttgtaa actactccca tcagaaaata gagaattcca tccaagagga
    11701 gaaaaagtcc caaagaaata ggttacaatt gcaattatca gcacagtcac taaatatatc
    11761 aaacaaggga tacttgcaac ttgcaaagtc aactttcttt ttaacccttg ataactcact
    11821 tctcttccaa tactcaatcg taaaacttta tttttcagct caatatattg aaaacctagc
    11881 aaaacaatga tgattggaat aataaatgat tgataaaaac ctagattgaa ctggagaata
    11941 cgaaaatcta atgctgattt taataagtca tttttaattg cttgtccatc gaatttagct
    12001 agatcgggcg catgaatatc aaaaaagaaa taagtcatca aaacatcacg ataaaccaaa
    12061 gcaagaaaaa gcaaagtaag caagacataa acaaatttat gccttgccaa agttaagaga
    12121 ggaatcttca taagccacct cctacaaata gaaagtaata taatactcaa tgaaaatcaa
    12181 agagcaaact aggaaactag ccgcaagttg ctcaaagcac tgctttgagg ttgtagataa
    12241 gactgacgaa gtcagttaca tatataatcc aaggcgacgt tgacgtggtt tgaagagatt
    12301 ttcgaagagt ataaatcaat gccttccgcc tttagacttc cctagttccc gtctcaagtc
    12361 aagcattttt ttgaaacaga tatagtctaa ccagtcacta gcaaaagcga taagtagtaa
    12421 taatagccaa ataccccata acttgatatc tgtcaaattt ctcaagacga tattgaaaaa
    12481 cagaactgaa aaaactgtcc aagcaaggct aaaaagagaa tagagggtga tgtaaatcca
    12541 gtaaaaatag taaaaaattg ggaaaaattt actttctcta ttatccttgt caatccagct
    12601 gaaaaagtaa aaacagggta ataagattat cattttaaac aagtgttcca tcacaagcct
    12661 ccttttttaa attgttttct ttagtttcgt tctattaaat gttattacca atataaacct
    12721 tggaatagcg tgtaataaat gattttagag gtaccataag ccacctccta caaatagaaa
    12781 ccgatataaa tcaatgcctt ccacccttag acttccctag ttcctgtctc aagcgaaaca
    12841 tttctttgaa acaggaataa gttaaccaat tcataccaat agctagcaga ataaaaagaa
    12901 accaaatgcc ccataacttg atatctgtca catttctcaa gacggtattg aaaaacagaa
    12961 ctgaaacaac tgtccaagca aggctaaaaa gagaatagaa ggggatgtaa aaccagtaaa
    13021 aataataaaa aattggaaaa aacttactat ttctgttggc cttctcaatc cagttatcaa
    13081 aataaaagta cggtgctaaa agtaagaatt taaacaaatg ttccatcacc gacatcaccc
    13141 tccttctttt gatagcgttt tctattattt tattatatca aaaaaatccg gaactgtcat
    13201 tccagattct acttttttat ctgcgttttc ttgcgatgag atgaatcggt gttccctcaa
    13261 aaacaaaggc cttgcggatt tgattttcca agaaacgcag gtaagaaaag tgcatgagtt
    13321 cttcttcatt gacaaagatg acaaaggttg gtggtttggt tgccacttgg gtcgcataga
    13381 aaatcttgag acgttttcct ttgtctgtcg gtgttgggtt gatggcaatg gcatccatga
    13441 tgacatcgtt caagacagct gatggaatac gtgtattttg actttcgctg atttgcttaa
    13501 tcatctcagg aagtttgtgg agacgttgct tggttaaagc tgatacaaag ataatcggtg
    13561 cgtaaggcag gtattggaac tgctcacgga tatcttcttc ccagtttttc atagtgtggt
    13621 tatctttttc aagcgtatcc cacttgttga ccacgataat catcccttta ccagcttcat
    13681 gagcaaatcc agcgatacgt ttgtcgtatt cacgaatccc ctcttccgca ttgatgacca
    13741 ttaagaccac atctgaacgg tcaatagcac gcatggcacg catgacagag tacttctcag
    13801 tattttcata aaccttacca gacttacgca taccagccgt atcaatcatg gtaaactctt
    13861 gaccatctgt atctgtaaag tgggtatcaa tagcgtcacg agttgttcca gcaacaggac
    13921 tggcaatgac acggtcttct cccaagatag cattaatcaa gcttgatttt ccaacgttag
    13981 gacgaccaat caagctaaac ttaatgacat ctggattttc ttcttcatat tcatttggaa
    14041 ggttttccac aatcgcatct agtacatccc ctgtaccgat accatggaca gatgagatag
    14101 gcagtggttc acccaaaccg agggcataga aatcatagat atcatttcgc atctcagggt
    14161 tgtccacctt gttgactgcg aggataactg gtttgtgggt cttataaagc ttacgagcta
    14221 cgtattcgtc tgcatcagta attccttcct taccagacac gacaaaaacg ataacatctg
    14281 cttcttccat ggcaatttct gcctggtgct tgatttgttc catgaaagga gcatcgacat
    14341 catcaattcc tcctgtatca atcatgctaa aagaacgatt gagccactca cccgttgcat
    14401 aaatacggtc acgtgtcact ccttcgacat cttctacaat ggagattcgc tcaccagcga
    14461 tccgattaaa tagggttgat ttcccaacat tgggacgtcc tacaatggca atagttggta
    14521 gggccataat ttctcacttt ctacaataat ttcttctgtt caagattttt tctagttgag
    14581 cttggttcag cttgaccaaa ctgttctgct agacgctgac tccagcttgt ggtcgcacgc
    14641 gccccagcat agtcagcctg aacacggtca taagcttgga ttgcctcagt tgactgttct
    14701 tggtattctt cctcaaagac aacattctct agtggcagtc tcggtttcat atcatgatgt
    14761 tgatttggca cacccagtgc catcccaaag acagaatagg tgtagtcagg taggttaaag
    14821 agctctgcca cttcttcaga cttgtatcga accaaaccga taatcacacc accatagccc
    14881 aagctttcag ctgccaacaa ggcgttttgt ccagcaagag ctgcatcgac cgaactaatc
    14941 aagagacctt ccacaccttg gggttggaag gtgtcggtat gaagtcgggc tcccttttct
    15001 gctcggttca aatctccgac aaagagaagg aaaacagcag actggcgaat ggcttcttga
    15061 ggtaccaatt catacaaggc atctttcttc tcttgacttc gtaccacaat cacagagtag
    15121 gattggaaat tcttccaaga tgatgccatc tgggctgctg tcaaaatctc atttaagtct
    15181 acttggggaa tttcttgctc tttaaacctg cgcactgaag tatgagcctt catcaattta
    15241 atggtttctg tcatcgacgg tttactcctt ctaaacgagt ctcctcagcc aaataacgga
    15301 tgcgttccat gacacgtctg gcttcccagg tttcgtcatt tccatttttc cctttagcga
    15361 aatgcttctc caaatcttca aagttgaagt tagaggtgaa aaaggtcggt aaattttcct
    15421 gcatccgata ttggagaatg acctgcagga tttcatcacg cacccaagcg gtggattgct
    15481 cggcaccaat atcatctaaa atcaggactt cagaaaactt aatctcatcc accaaggtct
    15541 taacattgcc atcactgata gcatttttga catcaatgac aaagctagga tagtggagga
    15601 gagttgatga aacaccacgt ttttctgata aatcatgagc taaggccgcc accatgaaac
    15661 ttttacccac accaaagtct ccatataagt aaagaccttt tcgaatagct ggatattgct
    15721 ccacgaaggc tagtagcttt tcaaaaactg gtaagcgccc caaatcatcc aagtcaactt
    15781 gagccaaact agctttcttg agactggctg gtagattgat taacttgaga cggttcttaa
    15841 tagccgcttc tttttcagcc gcgattagct caggagtttc ttcatatgaa acatctgcat
    15901 agccatgatt cttaaccaaa atcggcttgt agcctttggc aatataatcc gtatccccac
    15961 ggagaaactt gtcacgctcg gtgatgtact gattaaactt ggagatactg cgatttaatt
    16021 cctctggagt caaggattct tgctggataa aagccgcaac atcagggtcc ttcatgattt
    16081 tctggaccaa atcttgataa taaaaacggc tgggttgacg tttgagtacg tctccgacac
    16141 tttccatcta atctcctcct ttttctaatc gagctaatag ttcttgcttc ttacgttcta
    16201 gttccagacg agtttcctcg ctggtttcat tcttatattc aggattactc catttaggaa
    16261 cattggtttt tactggggca gtctgattct gtttttgtgt ttttgctttc tgtcctcgct
    16321 cacggatgcg caagactgcc ttttctgccg aatgaatctt ttgataggca tagtcattgg
    16381 ctaccttcat ggcatatttc tcattgatat ttgccgaatc gaccttatta aaggtcaata
    16441 aaagaatgat attgatgact tcgtccagca agcccaagcc agccatctgt tgcaagagtt
    16501 ctctttctgt ttgggtaatg gttcccttgc gtgtttgctt gatttctgcc aagaactgca
    16561 gggcagtttt acttttggct tctttgataa tggttgtttc cttaagacta aagtcagagg
    16621 aaactggttt ttgagcaatt ttttcacgca tgcgtttggt tgaaataacc tgagaaacag
    16681 ctgttgactt ggccaattga taggtttcaa accaagtcca tttcttctcc tcggcaatag
    16741 caaagaggtt taagacatcg gactgctcat ccgcaaaacg aagtccatct cgagccatca
    16801 gctggcgaaa atgttccaag tcaaaatcat tggccacttt cttcttgaga ccaaggtctt
    16861 cttgactgcc tagttctgcc aattctggaa agacttgatt gagtgagaca ggtatttctt
    16921 caccatcagc actttcaact ttcaaatcct ccacagcaga gtcgccaatc tttttctcta
    16981 agagtctgcg ataaacagga tgctccaaga agtcttgact agatagagga gcatggaggg
    17041 ctagctgata aacatccccc ttttgataga gggtcaagag attaaaagca gataagattt
    17101 tcaatgattt tatcagtcta tccatcccaa agttgagatg attgaggata cttgaaaaaa
    17161 gatattcctt tctaccatta tcccaaaaac tgattgtata aagataaagg ctcagtgcct
    17221 cctgaccgat aatcgggagg tagcactgta ccagagatga ggtatcttgc gacacccgat
    17281 tattctttag ataagaaaaa cggtcaattg gcttcattta tctttccttt ttctttttag
    17341 aggactgggt gatttgttgg agcaagctct ctaactcact gacatcctta aaactacgat
    17401 agacactagc aaaacgtaca taggtaatct cgtccaattc agccaactcc tccatgacga
    17461 gtgaaccaat gtcctcactt tgaatttcat tttcatttcg accacggagt ttctgttcga
    17521 tacgattgac taccatgttg atttcatcac ttgacacagg acgtttctgg gctgagcgga
    17581 taatcccatt aaagatttta tctctggaga attgttcccg tgtgccatct tttttaacaa
    17641 ccactaaggt tctttcttct actcgttcgt aggttgtaaa acggtgttgg cactcgtcgc
    17701 actctcgtct tctacgaatg gtgttccctt cttctgcttg gcgactatcg ataacacttg
    17761 acttggtagc cccacatttt ggacaacgca tcctttccct ccttatcgtt ttcttttcat
    17821 tataccattt tttaagcgat tcccaaaaca attcttcttt ttgcttgaca agttttttgt
    17881 tttgttgtat tatttaatta agacaaaaga ataagagaaa ggagactaag atgtcctgga
    17941 catttgacaa caaaaaaccc atctatttac agattatgga gaaaatcaag cttcagattg
    18001 tttcccatac actggaaccc aatcaacaac ttccaaccgt gagggagcta gctagcgagg
    18061 ctggtgtcaa tcccaatacc atccaaagag ccttatcaga ccttgaacga gaaggatttg
    18121 tctacagcaa gcgaacaact ggacgatttg tgactaagga taaggagcta atcgctcagt
    18181 cacgcaaaca attatcagaa gaagaattgg aacacttcgt ttcctccatg acccattttg
    18241 gctatgaaaa agaagaacta ccaggcgtag tcagtgatta tattaaagga gtttaagcct
    18301 atgtcattac tagcatttga aaatgtatcc aaatcatatg gagcaacacc agcccttgaa
    18361 aatgtttctc ttgacattcc agctggaaaa attgtcggcc ttcttgggcc aaacggctca
    18421 ggaaaaacaa ccctgattaa actaattaat ggcctcttac aaccagatca aggacgtgtc
    18481 ctcatcaacg acatggaccc aagcccagca accaaggccg ttgtagctta tttgcctgat
    18541 acgacctatc tcaatgagca aatgaaggtc aaagaagccc taacctactt caagaccttc
    18601 tataaagatt tcaatcttga acgcgctcat catctacttg cagacctggg cattgatgaa
    18661 aatagtcgtc tcaagaaact atcaaaagga aacaaagaaa aggttcaact gattttggtt
    18721 atgagccgtg atgctcgtct ctatgttttg gatgaaccca ttggtggggt ggatccagca
    18781 gcccgtgctt atatcctcaa taccattatc aacaactact caccaacttc taccgttttg
    18841 atttctaccc acttgatttc tgatatcgag ccaatcttgg atgaaattgt cttcctaaaa
    18901 gacggaaaag tcgtccgtca aggaaatgta gatgatattc gctacgagtc aggtgaatcc
    18961 attgaccaac tcttccgtca ggaatttaag gcctaagcaa aggagattat ttatgttttg
    19021 gaatttagtt cactacgaat ttaaaaatgt taacaagtgg tatttagccc tctacgcagc
    19081 cgtgctagtc ctttctgccc tcatcggaat acagacacaa ggctttaaaa atctacctta
    19141 ccaagaaagt caggctacta tgctactttt tctagctaca gtctttggtg gcttgatgct
    19201 tacacttgcg atttcaacca ttttcttgat tattaaacgc ttcaaaggta gtgtctacga
    19261 ccgacaaggc tatctgactt tgaccttgcc agtttctgaa caccatatca tcacagccaa
    19321 actaatcggt gcctttatct ggtcattgat tagcaccgct gtattggctc taagtgctgt
    19381 tattattctg gctttaacag ctccagaatg gattcctctt tcttatgtga ttacatttgt
    19441 agaaacacat ctccctcaga tctttcttac aggtatatcc ttcctactaa ataccatttc
    19501 aggaatcctc tgcatctacc tggctatttc cattggacag cttttcaatg aataccgtac
    19561 agcactcgct gttgcagcct acattggtat ccaaatcgtc attggattta ttgaactttt
    19621 cttcaatctt agttctaatt tctatgtcaa ttcactggta ggactcaatg accatttcta
    19681 tatgggagca ggtatagcca ttgttaaaga actcatattc atagctatct tttatctcgg
    19741 aacctactac atcttgagaa ataaggttaa tttgctttaa ataattttta cctagatatg
    19801 taacatactc atagaacaaa agagaccagg caaaaagtct ttaaaattag aaaacgcata
    19861 gtatcaagtg ttaaaaatcc ttgatattat gcgttttttg tgagctgact tatttccttt
    19921 cgctatatcg caaaatgaaa taagaacgga acgatgggat tttggaattc aaatcaattt
    19981 ataagaatgt tttagaagta atattatcct attccagatt cagttcacta tacaattgag
    20041 ttttcaagca acctgtttac ataatgtgta cataattagg ttcgtgattc cacccttttc
    20101 acctttaaaa acctcgcttt cgcaaggctc ttctatttat aagataaggc acgtttaaag
    20161 gttttccaaa tccctaaatc atccgtttga agaacgagac tagcatacat gcgtccgata
    20221 aatcctgttg ctaccaccgc aaaaatcact gtaatagcaa gtgaaatcca tgcttccgct
    20281 ccctccgcat agccattaat cgttcgaaac ggcataaaga aggtcgaaat aaagggaata
    20341 taagaaccaa tcttcaagag gagattgtca ccagctgcac ctagagctgt cactccaaaa
    20401 aaaccaccca taatcaaaat catcaaaggc gacaaggctt tccctgagtc ctcaggacga
    20461 gaaaccatag atcctaggaa ggctgccaag actacgtaca tgaaaagact gatcaaaata
    20521 aagagcaagg tattcagtga gatagcatct cccaagtgat ccaaaatacc agactgagcc
    20581 aagaatggca aatctttaaa gagcaaaacg gcagccagac cacctacaac atagatccca
    20641 atatgcgtta aaatcactag aaacagagcc atcatccgcg catagaaata gtgacttgcc
    20701 cttatgctag aaaagacgac ttccataatt ttggtgcctt tttcactggc aacttcctga
    20761 gctgttacac ccgcataggt aatcagaatc atataaagaa agaatcctaa ggcacctgct
    20821 gcaattgttt gaataaactt tttattttcc ttggcttcat caatcttttc tgtgaattga
    20881 attgtctgcg ctaagcgttt ttcctgctct tgagacaagg aagcagttga acgattaagc
    20941 tgattttgca gttcattgag tgtacctgta acctcaaatt taattccatt ttcaagcgat
    21001 gtttcgccat gataaactgc ctttagaaca ctatcttctt gatcaatggt caaataacct
    21061 tttaattttt cttctttaat tgcttctttg gcacttgctt catctttata gtcgaagtta
    21121 acaccattta cattcttcag tccttctgct acagatggca ctgttgtcac tactgccact
    21181 ttattatttt tagtcataga agaaccttgg agatgcccaa ttcctacaga gattcctaaa
    21241 aagaggaacg gcgaaatcac cataaagaag aaactccatg actcgacatg tcgaagatag
    21301 gtttccttga ttacaaccca catatttctc atacttccac tcctgattct agtttaaaga
    21361 tttcatcgat agttggcgct tgttggtcaa atgttgcgat atattgacct tgagtcaaga
    21421 ttgggaagag ttcccttcca gcgctctcat cctccaaaat caatttccaa ctgccttgtt
    21481 tggtcaagct cacctgtttg acatgaggaa gattttccaa ttcttccttg cttcgttcac
    21541 ttgaaacaaa gagacgcgtt ttcccgtatt gattgcggac atcctgaact ggtccgtgca
    21601 agaccacacg gccatctcgg atcatcagaa tatcgtcaca aagttcctca acattggtca
    21661 tgacatggtc agaaaagata atggttgctc cgcgctcttt ttcctgaaaa atgacttgtt
    21721 tgagcaattc tgtattaact gggtccaatc cactaaaagg ctcatccaag ataatcaggt
    21781 ctggttcatg aatcagagta ataatgagct gaatcttctg ctgatttcct tttgacagac
    21841 tcttgatttt atctgtcagc tttcctttca cttccaacct cttcatccat tgagggagtt
    21901 tttctttgac ttctttggca tccatgcctt ttagagtcgc caagtagcga acttgttcaa
    21961 gaactgtcaa tttaggcatg agactgcgtt cttcaggcag ataaccaatc cgagcatagg
    22021 tctcctgacg aatatcctga ccatccagac cgatttctcc ctgatattct aggaatttca
    22081 aaatactatg gaaaatcgtt gtttttccag caccattttt tccgactagt cccaaaatac
    22141 gacctggtcg cgcttgaaag tcaataccaa acaaaacttg cttggagcca aaacttttct
    22201 ctagacttct tacttctagc atctttcacc tccgaaattt cttgcactca ttatactcct
    22261 ttttgatagc ctttacaatg tttttgtcca tttttagaag actattgctg tgtaaaatat
    22321 ggcctggagc acttttatac tcaatgaaaa gcaaagagca aactaggaag ctagccgtag
    22381 gctgctcaaa gtacagcttt gaggttgcag ataaaactga cgaagtcagc tcaaaacact
    22441 gttttgaggt tgtggataga actgacgaag tcagtaacta tatctacggc aaggcgaagc
    22501 tgacgtggtt tgaagagatt ttcgaagagt attagtgata aatccattat acagtagcaa
    22561 acttaattta taccttccgc tcctcaactg tctattttta atcctgaatt gttatttgag
    22621 taactccttt ttcctcataa agttttcttc ctctaaaatt tctggaaaaa agcgaatagt
    22681 ttcagacaac atttttataa gaaacaagtt catctgtcat ttcaagaagg agtaatcctt
    22741 tatctactaa tggacggaac agaattcaac cgcttgtccg atatgttttc taaggattat
    22801 ataataaaat gaaataaaaa caggacaaat agatcgggac agtcaa
//
LOCUS       DAVKMO010000029        22727 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVKMO010000029 DAVKMO010000000
VERSION     DAVKMO010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22727
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.029"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..214
                     /locus_tag="VW361_001294"
     CDS             <1..214
                     /locus_tag="VW361_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744330.1"
                     /translation="IMHTTIGSNKNHNRFIRKWLPKPKGTKKTTTKEVAFIEKRINNY
                     PKKCLNYKSPREDFWMTNLNLKFSNN"
     gene            629..1246
                     /locus_tag="VW361_001295"
     CDS             629..1246
                     /locus_tag="VW361_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU9744331.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(1566..2453)
                     /locus_tag="VW361_001296"
     CDS             complement(1566..2453)
                     /locus_tag="VW361_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9744332.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(2602..4485)
                     /locus_tag="VW361_001297"
     CDS             complement(2602..4485)
                     /locus_tag="VW361_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9744333.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            4863..6317
                     /locus_tag="VW361_001298"
     CDS             4863..6317
                     /locus_tag="VW361_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9744334.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDKNWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGIYYELDYGRKTN"
     gene            6298..7263
                     /locus_tag="VW361_001299"
     CDS             6298..7263
                     /locus_tag="VW361_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9744335.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(7298..8572)
                     /locus_tag="VW361_001300"
     CDS             complement(7298..8572)
                     /locus_tag="VW361_001300"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU9744336.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIAGKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQANSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(8572..9744)
                     /locus_tag="VW361_001301"
     CDS             complement(8572..9744)
                     /locus_tag="VW361_001301"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU9744337.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(9875..10123)
                     /locus_tag="VW361_001302"
                     /pseudo
     CDS             complement(9875..10123)
                     /locus_tag="VW361_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(10236..10817)
                     /locus_tag="VW361_001303"
                     /pseudo
     CDS             complement(10236..10817)
                     /locus_tag="VW361_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10879..11328)
                     /locus_tag="VW361_001304"
     CDS             complement(10879..11328)
                     /locus_tag="VW361_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9744338.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(11330..12088)
                     /locus_tag="VW361_001305"
     CDS             complement(11330..12088)
                     /locus_tag="VW361_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9744339.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            complement(12203..14182)
                     /gene="pknB"
                     /locus_tag="VW361_001306"
     CDS             complement(12203..14182)
                     /gene="pknB"
                     /locus_tag="VW361_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU9744340.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(14179..14919)
                     /locus_tag="VW361_001307"
     CDS             complement(14179..14919)
                     /locus_tag="VW361_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU9744341.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(14934..16247)
                     /gene="rsmB"
                     /locus_tag="VW361_001308"
     CDS             complement(14934..16247)
                     /gene="rsmB"
                     /locus_tag="VW361_001308"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU9744342.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANDSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(16240..17175)
                     /locus_tag="VW361_001309"
     CDS             complement(16240..17175)
                     /locus_tag="VW361_001309"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU9744343.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(17188..19584)
                     /locus_tag="VW361_001310"
     CDS             complement(17188..19584)
                     /locus_tag="VW361_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU9744344.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVFGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLGKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVRRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(19650..19964)
                     /locus_tag="VW361_001311"
     CDS             complement(19650..19964)
                     /locus_tag="VW361_001311"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU9744345.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(19989..20615)
                     /gene="gmk"
                     /locus_tag="VW361_001312"
     CDS             complement(19989..20615)
                     /gene="gmk"
                     /locus_tag="VW361_001312"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU9744346.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(20745..22358)
                     /locus_tag="VW361_001313"
     CDS             complement(20745..22358)
                     /locus_tag="VW361_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU9744347.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
BASE COUNT         6312 a         5246 c         4484 g         6685 t
ORIGIN      
        1 tattatgcac accactatag gatctaataa aaatcacaac aggttcattc gtaaatggtt
       61 acctaagcct aagggaacta agaaaacgac taccaaggaa gtcgcattca tcgaaaagcg
      121 gattaacaac tatcctaaaa aatgcttgaa ctacaagtcc cccagagaag acttctggat
      181 gactaacttg aacttgaaat ttagcaataa ttaattcact atctaactat atttagtaat
      241 tatttcagaa ctgattaata ttaaaattaa ctaacaattc aaaggattca tactagccat
      301 aaattacgtc catcagagag agactcttac tacttttaga ttttagtctt tctaacttca
      361 gaatacatct aaactttagg gaaaatgact attcgaaagc gcgaatgcct caaaattatc
      421 tcagataagc tattcgaaac ttagaatgct tttaaattta tgtaattgcg attattcgaa
      481 acctagaatg catataacct ttagttgaca gacctattct aagtctcgaa gggctattta
      541 ctttctattc cttatcaaaa aagactcatt ccccctttct cctccaaaat atggtatagt
      601 agaaatatac tatctatgag gagtttacat gtcacaggat aaacaaatga aagctgtttc
      661 tccccttctg cagcgagtta tcaatatctc atcgattgtc ggtggggttg ggagtttgat
      721 tttctgtatt tgggcttatc aggctgggat tttacaatcc aaggaaaccc tctctgcctt
      781 tatccagcag gcaggcatct ggggtccacc tctctttatc tttttacaga ttttacagac
      841 tgtcgtccct atcattccag gggccttgac ctcggtggct ggggtcttta tctacgggca
      901 catcatcggg actatctaca actatatcgg catcgtgatt ggctgtgcca ttatctttta
      961 tctagtgcgc ctatacggag ctgcctttgt ccagtctgtc gtcagcaagc gcacctacga
     1021 caagtacatc ggctggctag ataagggcaa tcgttttgac cgcttcttta tttttatgat
     1081 gatttggccc attagcccag ctgactttct ctgtatgctg gctgccctga ccaagatgag
     1141 tttcaagcgc tacatgacca tcatcattct gaccaaaccc tttaccctcg tggtttatac
     1201 ctacggtctg acctatatta ttgacttttt ctggcaaatg ctttgacacg taaaaaatcc
     1261 gtttggtttc ccaagtggat ttttaaagcg tagattaact atagcttgat actaaatata
     1321 ctttggtatg gaaatcatgc atatttttcg atagtgaggc gaggacttac ctagcctttc
     1381 cgccgtgata gaaacacctg aaatctaatg gtttcaggta ttcggaaact ttgagacact
     1441 aggctcaaag tttaggtatg gaatttcgaa gaaagtcgct accgtccgta atcacttaag
     1501 gaaaggctca aaaatattgt tttcaaccac aaaatccgct tgggaaacca aacggatttt
     1561 gtgctttatt ttgaaacttc ttttgcaaga acaaagttcc caagtgtggc agaaccattt
     1621 cctgcgactg ctggcgtcac gatatagtca cgcacatctg gtactggtag gtaaccatta
     1681 agaagagatg taaatttctc acggacacgg tccagcatat gttgttgagc catgacccct
     1741 ccaccaaaga caatcacgtc tgggcggaaa gtcactgtcg cattaaccgc agcttgagcg
     1801 atatagtagg cttgaacatc ccaaacaggg ttgttgagtt caatagtttc cccacgtaca
     1861 cctgtacgag cttccaaact tggaccagct gcataacctt ctagacatcc cttatggaaa
     1921 ggacaaacac ccttaaactc tttttcaata tccattgggt gtctagcaac ataataatga
     1981 cccatttcag ggtgacccac accaccgata aactcaccac gttggatgac gcctgcaccg
     2041 atacctgtac cgattgtgta gtaaaccaag ttttcgatac gaccaccagc attgttacgg
     2101 gcaaccactt caccgtaagc agagctgttt acgtctgttg tgaagtacat tggcacgttt
     2161 agggcgcgac gaagggcacc aagcaagtcc acatttgccc agtttggttt tggagtcgtc
     2221 gtgataaagc cataagtttt tgagtttttg tcaatatcaa tcggcccaaa tgaaccaact
     2281 gcaagaccag caaggttatc gaattttgag aagaactcaa tggttttatc gattgtttcg
     2341 attggagttg ttgttggaaa ttgtgttttt tctacgacgt taaagttttc atcaccgaca
     2401 gcacagacaa actttgtacc gcccgcttcc aagcttccat ataattttgt catgataaac
     2461 ctcttgtttt tattttcttt attatagcat acttcgaaag tctaaatgtc tctatttttt
     2521 agattttcct ctgtaaatct tactatctaa taaaaacgaa caaacatgtc atttgttcgt
     2581 tttcacatta gagaggattg attagatttt cacttcgatc acagcatccc ccttcgcaac
     2641 tgaacctgtt gcgactggag ctactgaagc gtagtcagct gtatttgtaa cgataaccat
     2701 tgttgtatca tcaagtccag ctgcagcgat tttgtttgag tcaaatgttc caagaacatc
     2761 gccagctttc accttattac cttgagcaac ttttgcttca aaaccgtcac cgttcataga
     2821 tacagtgtca ataccaacgt gaatcaaaac ttcagcacca tttcttgttt tcaaaccaaa
     2881 agcgtgccct gttggaaagg caattgaaac ttcagcatca gctggtgcat agaccacgcc
     2941 ttggcttggt ttcacagcga taccttgtcc catagctcca cttgagaaga ctgggtcatt
     3001 gacatcagca agagcgacaa catcaccgac gataggagtt acaagtgttt cattttgaag
     3061 agctgctggc gcaacttctt ctttttcttc agccacttca gcttgttttg cagctgcagt
     3121 tgcgtctact tcatcttcgt aaccaaacat gtaagtaaga gcaaaaccaa gggcaaatga
     3181 tacagctacc ataagaaggt attgtggaag ttgtccgtta ccaacataaa gcattgtacc
     3241 agggatgatg gtgataccat taccagtacc agcaagtcca aggatagaag ccaatccacc
     3301 accgattgca ccagcaatca atgaaaggaa gaatggttta cggaagcgca agttcacccc
     3361 gaagatagca ggctctgtaa tacctaggaa ggcagaaaga gcagccggga aagcaagtgt
     3421 tttcagtttt ggattttttg ttttaacacc aaccgcaaca gtagcagcac cttgagctgt
     3481 catagcagct gtgatgatag cgttgaatgg gttagcatgg tcagcagcaa gtaattgcac
     3541 ttcaagcaag ttgaagatgt ggtgcacacc tgacacgacg atcaattggt gaaccccacc
     3601 aatcaagaaa ccaccaagac caaatggcat gctaagaatc gcttttgtag caataaggat
     3661 gtagttttca acaacgtgga aaactggtcc aatgacaaag agtccaagga tagacatgac
     3721 caaaagtgtc acgaatggtg ttaccaagag gtcaatgaca tctggaacaa ccttgcggac
     3781 agctttttca aatttagctc cgacaacccc gatgatgaag gctggaagaa cggaaccttg
     3841 caaaccaaca acagggatga aaccaaagaa gttcatcgct gttacttcac caccttgagc
     3901 aactgcccaa gcgtttggaa gtgagccaga gacaagcatc ataccaagaa cgataccaac
     3961 ggcaggattt ccaccaaata cacggaaggt tgaccacaca accaaacctg gcaagatgat
     4021 gaaggctgta tctgtcaaga tttgtgtgta agttgcaaag tcacctggaa gtggcatttc
     4081 aagagcgttg aaaagaccac gcacacccat gaagagacct gtcgctacga taactgggat
     4141 gattggaacg aaaacatcac cgaaagtacg gatagcacgt tggaaccagt tcccttgttt
     4201 agcaacttct gctttcatgt catccttaga tgatgttggt aagccaagta caacaacttc
     4261 atcgtacatt ttgttaactg tacctgtacc aaagataatt tggtattgcc ctgagttaaa
     4321 gaaagcacct tgaacttttt ccaagttctc aatcacttct ttattgattt tctcttcatc
     4381 tttgaccatg acacgtagac gagtcgcaca gtgggcaaca ctattgacat tttcacgtcc
     4441 gcccaaggca tcgatgactt tttttgcaat ttcctgattg ttcatttgca aaaatctcct
     4501 tatataacat tttgttcttg tttgaaagcg attttattcg cccttacgac tattatttta
     4561 tcatgtttta aaaatatgtc aagcgttttg cagaaaaaaa tattctatcc acttagtggg
     4621 caagctttag attgattgtt tttgactgtt tcatcaggaa ttccttgaaa aataagtttg
     4681 aaaccttggt taaaaagtat tttatttcat tatctttcac attttcgtaa aaatttgatt
     4741 gatttcctgt atttatttta tgataatcgt ttgacagttt tttctctttt ttaatataaa
     4801 aggcttgcat tttttatcga aaacagttac tattaaaagt gataagattt ttggaggaat
     4861 gaatggaatg gacaactgag cgtcgttaca gactttatca agattggacg caagaagaaa
     4921 ttcaacatat aaaggaaaat atggcacaat ctccatggca tactcattac catgttgagc
     4981 caaaaacagg acttctcaac gacccaaatg gcttttctta ctttgatggc aagtggatcc
     5041 tcttttacca gaattttcct tttggtgcag cccacggttt aaaatcttgg gcacagctag
     5101 aaagtgatga tttgattcac tttaaagaaa ctggaatcaa agttttacca gatactccat
     5161 tagatagcca cggtgcctac tctggttctg ccatgcaatt tggcgataac ttattcctat
     5221 tttatacagg aaatgttcgc gataaaaact ggatccgtca cccataccag atcggtgctt
     5281 tgatggacaa ggagggtaag attacaaaga ttgacaagat cttgattgac cagccagcag
     5341 actctactga ccacttccgc gatccacaaa tttttaactt tcagggtcaa tattatgcca
     5401 ttgtcggcgg acaagacttg gagaaaaaag gtttcgttcg tctctacaag gctgtcaata
     5461 acgactacac aaactggcaa gcagttggcg accttgactt tgctaacgac cgtactgcct
     5521 acatgatgga atgtcctaat ctggtctttg tagaggaaca acctgtcctt ctctactgtc
     5581 cacaaggatt ggataagaaa gttctagact acgataatat ctttccaaat atgtataaga
     5641 ttggggcttc ctttgaccct aaaaatgcca aaatggtaga tgtgtctcaa cttcaaaaca
     5701 tggattacgg tttcgaagcc tatgcaactc aagccttcaa cgctcctgat gggcgtgctc
     5761 tagcagttag ctggcttggt ttgccagatg tttcttaccc atctgaccgt tttgaccacc
     5821 aaggaacctt ctctttggtc aaggaactca ctatcaaaga cgacaagctc taccagtatc
     5881 cagtcgctgc tattaaggac cttcgtgctt ctgaagaagc cttctcaaac cgttcccaaa
     5941 ccaagaacac ttacgaactt gaactcaact tggaagctaa tagccagagc gagattgtct
     6001 tacttgctga taaagaaggt aagggacttt caatcaactt tgaccttgta aacggtcaag
     6061 tgacagtgga tcgtagccag gctggagaac agtatgccca agaatttggg acaactcgtt
     6121 cttgccctat cgagaatcag gctactactg ctacaatctt catcgataac tctgtctttg
     6181 aaattttcat caataaagga gaaaaagtat tttctggtcg tgtcttccca catgcggacc
     6241 aaaatggtat cctgatcaaa tctggaaacc caactggaat ttactatgaa ttagattatg
     6301 gtcgcaaaac taactgatgt cgccaaactt gcaggcgtca gtcctactac cgtttctcgg
     6361 gttatcaata aaaaagggta tctatctgag aaaaccatcc aaaaagtcaa tgaagccatg
     6421 agagaattgg gctataaacc caacaacctg gctcgtagtc tgcaaggaaa atcagctaag
     6481 ttaatcggct tgattttccc caatatttcc aatgttttct atgcagaatt gattgataaa
     6541 ttggaacacc aactcttcaa aaatggttac aagaccatca tctgcaacag tgaacatgat
     6601 tctgagaagg aacgcgaata catcgaaatg ttggaagcca atcaggtaga cggcatcatt
     6661 tctggtagtc acaacctagg aatcgaagac tacaatcgtg tgacagcgcc gattatttcc
     6721 tttgaccgaa acctatcgcc agacatccct gttgtctcct ctgacaacta tgctggtggg
     6781 gttcttgctg cccaaacctt ggtcaagaca ggtgcccagt ctatcatcat gattacaggg
     6841 aatgacaatt ccaattcgcc aaccggactg cgccacgctg gttttgcatc cgtactccca
     6901 aaagctccta ttatcaatgt ttccagtgac ttttctcccg tcagaaaaga aatggaaatc
     6961 aagaatatct tgacccggga aaaaccagat gccatttttg cttcggatga tttgacagct
     7021 attctggtca ttaaaatcgc tcaagaattg ggaatttctg tcccaaaaga gctcaaggtc
     7081 atcggctatg atgggaccta ctttatcgaa aattactacc ctcaattggc tactatcaag
     7141 caacctttgg aagagattgc ttgtctcact attgatcttc tcttgcaaaa gattgaaggc
     7201 aaggaagtcg ccacaactgg ttacttctta ccagttacgc tattaccagg aaaaagtatt
     7261 taaacacaag aaaactcaga ccgattcgtc tgagttttta tgatcttaaa ttttcgagat
     7321 agcgctgggc tgtctctagg ttaaaggttt tatctgcgat aagctgctcg actaggggag
     7381 caacttcaga ttcactagcc ccagctagga gagctaggga gttggcctgt agtttcatgt
     7441 ggccttgctg gatgcccgta cttaccaagg ctttgagggc tgcaaaattt tgggcaagac
     7501 cgatggacac gataatctgg gctaattctc tggcagaagg atttcctagt agatcatgac
     7561 tgagagctac acgtgggttg aggccgatag agccaccctt agtcgctaca ggcatgggca
     7621 gggtcatctc accgaccaat tcttctcttt caaggtccag cgtccagcaa ctaagacctt
     7681 gataacgtcc atctcgactg gcaaaggcat gggccccagc ttcgatggca cgccagtcat
     7741 taccagtggc aatcaaaatc gcatcaatac cattaaaaat tcctttatta tgagtagcag
     7801 ctcggtaagg atcagcctgc gcaaactgac tagccaacgc aattttctcc gcaatctctc
     7861 gtccttgatc cttttggcgg ctcaagtagc gaaaggcgat gcgacagctt gcagtcacca
     7921 gagaatcggt cgcgtagttg gacaggattc ccatgagact ctgtccctga ctgagttctt
     7981 ctaagactgg tttcaaggct tccagcatgg tgttgagcat attggcaccc atggcttcct
     8041 gggtatcgac atgaatataa acaacgagaa agtctggttc accttttatc tgctcgacat
     8101 gcagatcacg cgccccacct ccacgtttaa cgatagaagg ataggcttga ttggcaagct
     8161 ccaagagctc cgctttcttg ccggcaatct tctcttgcgc tagtttagga ttagcaactt
     8221 gataaagggc tacctgccca atcatctgtc gctgatggac ttgtgcagta aaaccacctg
     8281 cacgcttgat gattttgctg gcatagctgg ccgccgcaac cacagagggt tcttctgtca
     8341 catagggaac ggtgtattcc tgaccgttga caagtacctc cggaaccagt gaataaggca
     8401 gagaaaaagt tcccactaca ttctcactca gctggtctgc cacagtcacg ctcatctgtt
     8461 catccttctc cagactagct tgtctctcag gactaaggag cgcctgagct tttaacagct
     8521 cgaggcgctc ttggtatgat tttttagaaa atccattcca acttatcttc attatttttc
     8581 aaccttgcta taacggcgtt ggtggtcgag aatttcaacc aaggcaaaat cttgattttc
     8641 atagccagca aactgggcag agtttgtttc atccaagttt acttcctcaa aaaagacctt
     8701 ttcatagtct gcaacggata gggcagttcg ttggttgagc ttgttcaagc ggtctttatc
     8761 caaataagct tcatatcctt caaccaattc accactgaag aactcagcca cagctccact
     8821 tccgtaacta taaagggcga ttttatcccc agctttcaag ctatctgtat tttccaagag
     8881 agacaaaagt ccaaggaaaa gtgaacctgt gtagatattc cccacctttt gactgtagag
     8941 aatagactgg tcaaaatgct tttgtaagag gtcttttttc tcttgaggca ggctcttatc
     9001 catgattttt ttcaagcctt ttagcgctaa tttaggataa ggcaagtgga aacaaacagc
     9061 cgcaaaatca tccagagtaa gctggtagcg tttttgatat tcaagccaag tcgttttcaa
     9121 actatccaag tattgttggg tagaataaac accatttaca taaggagttg tcgagtaatt
     9181 tggtcgccag aaatccatga tgtcacgggt ctgagctaca ttgtcattat taaaggccat
     9241 catgcgtgga ttttgtgtaa tcaacatagc tacacttcca gcaccttgag ttggttctcc
     9301 tggagtttca ataccgtatt tggcaatatc actggcaatg accaagacct tggactccgg
     9361 agaattttcc acatgcaatt tggcataatg aagggcagca gtcgctccat aacaggcttc
     9421 tttaatctcg aaactacgag caaagggctg gatgcccagc aagccatgca caaagacggc
     9481 cgcagcctta ctctggtcaa ttcctgactc ggtagccaca atgaccatgt caacttcttg
     9541 tctttcttgc tcagttaaaa tagagtcact agcactggcc gccaaggtca caatgtcctc
     9601 agttaggggc gcaatactca attccttgag taagagtcct ttacttaatt tttcagggtc
     9661 aattcccctc gcttctgcta agtcttgtaa tttcaagaca tattgactgg tcgcaaaacc
     9721 aatcttatca ataccgattg tcatatttac ctctgtttta tcattcatgt aaaaaatcgt
     9781 tctatactat tttatcacaa atggcagtaa aagagagaaa aaagacttga ttcaccaaat
     9841 caagcctctt attggtcatc attttaaaga atgattagtt gctagaaagt tcaccgatat
     9901 aagtagcttt ataagcttca ttcacagtta tcagctcctg gaggatcaaa tttcctgagt
     9961 aagtccttcc catctcatct acaaattctt gataaaactg actggtcgga atttctctga
    10021 catccttatc aaatgtcttg tcaagtgttt tactaacctt ctcagcaatc aattgatgct
    10081 cttaccatcc actttgaaac tctgagcccg aactagaaac catgactggg ataaacaaca
    10141 aggtcagtag atttacagac aataaggaaa gtagtagact tcctgcaaaa ctagaatcct
    10201 agttcatgat tgataatgcc agcaatcaaa ttcattcata atccgaagcg tttacgatga
    10261 tttcaatagg ttgttgaaaa cattttaaac gtttttactt tggcaaagat gttctcaacc
    10321 ttgcttctct ccttggatag cgcatggtta taggcttgat cttcaactgt tagcggtttg
    10381 agtttgctgg atttacgtgg agtttgtgct tgaggatata tcttcatgag cccttgataa
    10441 ttactgtcag ccaagatttt accagcttgt ccaatatttc cgcgactcat tttgaacaac
    10501 ttcatatcat gacaatagtt cacagcgata tccaaagaaa caattctccc ttgacttgtg
    10561 acaatcgctt gaggttccat agaatgacat ttctatttta ccagaataat tggctagttg
    10621 atttttttag gacgatttat ttttacctct gttgcatcca caatcaccgt attctcagca
    10681 ctaagatgag tttttgaaat cgtaacacca ctttgaacaa gagttacttc aacccattgg
    10741 ctccgacgga ttaagttgct ttcgtggata ccaaaatcag ccgcaatttc ttcataagtg
    10801 cggtattctc gcacatatag aaagcgttgt taatttattt atctcatttt tcagaaaatt
    10861 cttttatttc tgtaaagtct acgatactcg atgtgttttt atataatgat acagtctgag
    10921 aatcactgtt ccactagcca ttccaataga gattaccaaa gccaacatga caaccaaggt
    10981 cgcacttgcc agtgctttat tatagtcccc tgtcacaaaa aaggcagttg ttcggtagga
    11041 gagataacct ggaaccagcg gtgccaaaat ggccaagata aagaccacag caggtgtctt
    11101 ataaagaata cttaaaatct ggctgacaca agaaccaata atggctgcaa tgaaggtagc
    11161 tacaatgaca ttggtcggtt ccttgagcaa gagatagatt agccagacag tcatgcccaa
    11221 aatccctcca ggtaagagca tagaccgttg cacattgagt acgattaaaa aagtgataat
    11281 ggcaagaaaa cttgctactg cttgtaataa aaaggttgtt agtgtcatat tagttcatca
    11341 ataccaaggc gacagaagtt cctgccccta aagcgagggt aatgagcagg gattcaaaca
    11401 tcttactcat accagagttt atgtggttgg tcataatatc acggaccgca ttggtcaagg
    11461 caatacctgg tacaaacggc atgaccgcac cagctataat caaatctgcc gttgaaggaa
    11521 aacctgtgta gcgagcccaa aattgggcaa ttatcccaaa gacaaaggct ccagcaaagg
    11581 ctgtcacaaa gggaattcgg ataaattttt ccacatagag ggaaaaggca aaaccaaata
    11641 aggtcgccac tcctgcccca agtgcgtcgt agatatttcc gctaaacata actgaaaaga
    11701 aaggagcact aaaggtcgca gccagagtta cctgcaactt agtataggga aggggttgag
    11761 cttgcaaggc cgtcaattgc ttaaaggctg tttctaagtc aatctgcccc ccaactagct
    11821 gacgagaaat ctggttcaca tcgcagactt tttcgatgtt ataagaagag gaggtcacgc
    11881 gcttcatgcg cgaaatattg gtattttcaa tagagaaaaa gatagcggca ggcatggcaa
    11941 ggacattgca atccacaatc ccctgcgaat gcgcgattcg aatcatggta tcttctacac
    12001 gatggatttc tgagccactt ttaaggagaa tagtccccgc tagcataatc acatcaatga
    12061 cggcatttaa ttcttttgat tcttccatgc tttcctcctt ttatcaactc cctctattct
    12121 atcacaaatc tggactcaaa aaaaatcttt gccatgaaat catgacaaag attgattact
    12181 cattttgatt atccatctgc ttttaaggag tagctgaagt tgttttaggt ttgtagattg
    12241 aaatcttgac tctagtctta ttgaggtcta ccttttcacc tgctctagga ctttgttcaa
    12301 caaccatgcc ttctgcacta cctgcaggcg ctgtcgtcac ttctacaact tctatattag
    12361 cttccttaat cccaacaatt tgaatcaaat tgttcttagt aaactccaag ctggaaccaa
    12421 tgtaactcgg catggcaaca cttgtaactt ttttagctac tgtcaagaca atttgagtag
    12481 gtttactcac atcataagtc gttccggcac ctggactttg tttcataatc gttcctggtt
    12541 cgctttcgct ggactcttct tcctctatct taatcaaatt ctcaggaacc ttcttctgct
    12601 tgagttctga gattacttct gtagagttcc gtccaatata gttccctaat tgaatcgtcg
    12661 tagctttttt agctactgtc aaaacaattt gagttgcctt gctcaagtca taggtcgtac
    12721 cttctggtag actttgcttc aagaccgttc cagcctcact ctcattcgac tcttcttcct
    12781 caattttaat caaattatct ggaacttttt tctcttttaa ttccgcgata acatcagaag
    12841 atttccggcc gacataatta ctaatttgga aggattgttt gcctgatgag acaaccagat
    12901 tgattttcgt tccttctttt cgaccagttc cagcgccagg atctgtacgg ataatccgcc
    12961 cttcttccac cttttcacta gcctctgtct tctcctcacc aatctcaaaa ttggcttttt
    13021 tgagcgttgc cttggcctct gcaactgtct gacctgccac atctggaatg gcaatggttg
    13081 caggagttct ggatagtatc caaataagag aagctgccac caatacaagg ctggccaaca
    13141 aaatcaggta acgcatctta aatctatgtt ttttcggtgc ttgtggttgg taagtttcct
    13201 ctgtcacagc ctggcttggg tttttgattg atttgtgttc tgtctgcgct tgaaccttag
    13261 gaatagatgt caaggtactc tgagaaacct tcggcaaggt cttggtatct gccttgctcg
    13321 tttcatcaaa gattaactta ctttcatttc tacgattgta ggacaagcta ctagacaagt
    13381 ccacatacat ctctgaaacc gagcggtagc gattggtcaa ctttttagca gttgccttga
    13441 taataacatt ttctaaagcc tgaggtacag atggattttc tgcaataacg gacggcaggg
    13501 gtttctggaa atgctggagg gcaatggtca ccgcgctatc cccgtcataa gggatatggc
    13561 ctgtcaacat ctcatagaaa ataatcccca tggcatagat atcactctgc acagtcgcct
    13621 tcgaaccacg cgcctgctct ggtgacaagt aatgaactga gcccaacatc gagttagtct
    13681 gggtcagact tgtctctgca aaggctacag caatcccaaa gtctgtgacc ttggccgtcc
    13741 catctggtgt caaaaggata ttttgaggtt tcaagtccct gtgaacaatt cctcgagtat
    13801 gggccaagcg catagccaag agaatttgtc ccatgatacg gactgcttct tcattagaaa
    13861 gaggataatg ttccttgata tagcgtttga ggtctagtcc agcaacatac tccattgcaa
    13921 gatactgttg accgtcttcc tcaccaatat ctgttatccg aacgatatga ggatggtcta
    13981 gatctgccat agctctcgct tcacgctgaa aacgagctac agctatcggg tccgtctggt
    14041 agttggtcct cagaaccttc actgccactt cttccccatc taagattaag tctttggcta
    14101 ggtagacatc cgccatgcct cctcgaccaa tctgtttgac aatccgatag cgtccggcaa
    14161 aaatcttgcc gatttggatc attctgcatc ctcctcgttc atagaaacaa gggcaaccgt
    14221 aatgttgtct aaacctcctg cattgttagc aaaacgaaca agtgtctccg ttttatctgc
    14281 taaaggaata tcactggtta caatatcacg aatctcactg cctgaaatca tgttggtcaa
    14341 gccgtcacta ttgagcaaaa gatagtcacc tgactcaagg ataactgtcc caaaatcagg
    14401 ctgaatttca tctttttgcc caatagactg ggtgataata tttttttgcg gatgagcttc
    14461 tgcctcttct ggtgtcaatt gaccagcctt gagcaattca ttaaccaagg aatgatcgct
    14521 cgtcaactga tggtattctt ctccacgaat caagccgata cgcgaatcac caatatgagc
    14581 atagatagcc tgattatcaa taatagcaag gacttccaaa gtagttccca tgcctctgta
    14641 agcttcatcc tgaccaagct ggtgaatctt ttgattttca atttctaggt aatgggcgaa
    14701 ccattcacgc acttcattga ctgtatcaat ctgggtatca acccaagcta cacccaggtc
    14761 tgtgaccgcc atttcactag cgatattccc tgcgcgatga cctcccatcc catcagctaa
    14821 aataatcatg gtacgtccag ctctattgac atagtggttg acatagtctt ggttatttgt
    14881 tcgtttctga ccaacatctg ttaataatga aatttccatg tgtcagttcc ttcctaatcc
    14941 gatatcttgc gaaattgact gatgaagaat ccatcacttc catacaattc aggtgtaatg
    15001 aggatacagc cgtctttcat gatatcctta cattcatgtt ctagttttac ctgctcgaac
    15061 tcgggatgac tctctaaaaa ggccttaacg acttgaaaat tctcctctga gacgatagtg
    15121 caggtgctat aagttattat accacctttg cctagtattt gacaaacact acctaatatt
    15181 tctaactgaa tttcctgcaa ggacgcgaaa tctgccgttt ctttattgta tttgatatct
    15241 ggttttcggc gcaaaagacc gattcctgaa caaggagcat ccaccaaaat cttatcaaag
    15301 gaatcctggt caaaaaactc atgcaccttt ctggcatcca atttttgagt ttgaacccga
    15361 tcttcaactc ccagacgttg ggcattttct tgaattaaat ccaacttgtg gtcgtacaag
    15421 tccagagcag taacctgacc tgtcgtaaga taagaggcta tatgggctgt tttcccacct
    15481 ggagccgcac aggcatcaag cactcgctca tcaccttgta aatcaagcgt cggagcaacc
    15541 agctgactgg actcgtcttg gatggtaatg gctccatccg caaacaaatt atgccctgca
    15601 aaatgcccct gctccttaac cagaccagtg gttgctaaaa gggaatcatt cgcctccaac
    15661 aaggcttgga tttcctcttt tcgacttagg tctgttacac gaatactggc tttgtttcgc
    15721 actaacaggc tttcaaagat ggcttttgct ctctcctctc cgtattcttc cttgagtttg
    15781 gcaactagcc aaactgggag agaataggca atggagtcac gcttgttttt tcgcttgatg
    15841 ctagcaatat ctggccagcc ttcacgcaag atacggcgaa ggacagcgtt gaccaatttt
    15901 tcactgcctt ttttacggag tttggccaat tccactgctt cattgaccac agcatgatct
    15961 ggaatcttgt ccaaatagcg gagttggtag gcactcatga gaagaaggac atagagccag
    16021 ctgtctaact ggtctctgtc ttcgataaag tgggataggt accattccag agtcagttta
    16081 cgggctaccg ttccatagac tagctcggtc actaagccct tgtctgctgc agagagctga
    16141 ctccccttga ggtgtttatt taaggcaata tttgaatatg cttgattcac aaaaacatcc
    16201 tctagcactg ctagagctaa acttctagcc gtttctactt tagtcaccaa atcgttctcc
    16261 tacagtcaat gtacgtccaa ctccattgag gaaggaagca atgtccatct taggcttacc
    16321 agctggctgc acttgtttga gggatagagc cccttcagcc gttgcgacaa tcaattcttt
    16381 cttgccgata gagagaatct cacctggatt tccctgacct tctactggta gggcttcata
    16441 aatcttaaag cggtcgccct taaggaaagt atgggcaaca ggccaggggt tcattccacg
    16501 aatttggtta aagagttgac gattggtttt gttccagtcc agtttttctt cctctggctt
    16561 tatatttgga gagaaggtaa cctgactcgt atcctgcggt tcaggtttga tatcaccagc
    16621 aatataggca ggcagagtgt ccaaaagcaa atcacgacca actagcgcca atttttcaaa
    16681 caaggtgcca acattgtcct catctgtgat cggaatgctg cgacgagaaa tcatatctcc
    16741 tgcatccatt tccttaacca tttccatgat ggtcacacca gcttcctcat ccccttgaat
    16801 caaggcataa tggataggcg caccaccacg gtgtctagga aggagggagg catgaacgtt
    16861 gacagcaaag tccatgctat caaggagttt gcttgggaga aactgcccaa aagcagcagt
    16921 cacaattcca tctgctccta gcttcataag ttcttccatc tctggacttc cagataattt
    16981 ttcaggttgg tagatagata gtcctgcttc cttggcagcc tgcttgactg gggtttcttg
    17041 gataactttt ttacgaccaa cagcacggtc tggctgggtc acaacggcta gaatttcgta
    17101 acggtcatct gtcaaaagtc cttttaagac tgttgctgaa aagtcggggg tccccataaa
    17161 gattagtttt gtcatatctt ctccttctta taaaaattgc tgcggctcat ggtcaatgct
    17221 gagacggagc tcactatttt cccgttcttg agtcaaggcc aagacctggt tgagggtcgg
    17281 ccccagctca tcttctaaac ggtatttaat taaaatctgg taatgataga ggttgtgggt
    17341 acgggcaatc ggttttggcg ttggccccag aatgggactg gtctctgaca agcctgaccg
    17401 caaaatgttc atgacttcat aggcacgttt gaaaacctct tcttctttct tgtgagaaag
    17461 ggtaatacca atcgtgaaat agtaaggtgg atagccgagt tgtcgtctga ttcccatttc
    17521 ataggcataa aagccttcgt aatcttgatc cttggcaaat cgaatagcat agtgctgcga
    17581 attgtaggac tgtatcaaga cttgacctgc tttttcagcc cgacctgctc gacctgccac
    17641 ctgagtcaag agctggaagg ttctctcaga agaacggaaa tcaggcagat tcaaggccgt
    17701 atccgcattt agaactccga ctagggtaac attgggaaaa tccaaaccct ttgcaatcat
    17761 ctgagtacca agtaaaatat ccgcttcccc tcgcccaaac tggtcaagca aggcttggtg
    17821 actgcctttc tttcgagtcg tatccacatc catcctcaaa atgcgagctt ggggaaagag
    17881 ttctgctagc tcatcataag ccttctgagt tcccgtccca tagtaacgaa tactgtggct
    17941 cttacagtta ggacagacct gaggaatatc cttcgagaaa ccacaataat ggcagttcat
    18001 agtcttggta tccatatgca aggtcagaga aatatcgcag ttgggacaag tatccaccgt
    18061 cccacactcc cgacacatga caaagctaga ataaccacgg cgattgagca tgagaaccac
    18121 ctgctctttt ttaaccagac ggtcttggat agcctctagc aaaggaggcg taaagtttga
    18181 cgtctcattt tgtccgatat agtctcgaaa gtcaatcact tgaacctcag ggattgtagc
    18241 caaaggattg gcacgttggg ttagacgtaa gtgttgatag acgcctttgc cagcacgtgc
    18301 ccggctctct aagctcggcg ttgcagatcc aagtaccaga gttgcttgat tatactgagc
    18361 ccgtaaaata gctacctctc tggcatggta acggggattg ctgtcctgct tataagccgc
    18421 ttcatgctct tcatcaataa tcatgacacc cagatttttc agaggagcaa agatagcaga
    18481 tctggcacca acaacaactt gggcatcgcc acgctccacc ttgcgccatt catcatactt
    18541 ttcgccattg gataatcctg agtgaagaat ggctaccttg tccccaaaac gtgctataaa
    18601 acgctcggtc atctgaggag tcaaggaaat ctcaggtacc agcaaaatag ctgtcttgcc
    18661 cttatccagg gcaccttgga taatctgcaa gtaaacctcg gtcttcccac ttcctgtaat
    18721 cccttgaagt agaaagggag gttgagaact gccaatagaa ctcacaaccg catcacgcgc
    18781 ctgtctttgt tctggattta actccaaagg tctacttgct tcaattcctt caaaataagc
    18841 agccgagcgt cgaacttcct tttggactat ggtaacagca ccttgatcca caaagaagtt
    18901 gacttgctct cgcgagtagg actctaacaa gctagccaag gaagcgctct ctggatgaga
    18961 cagcagataa tctctcagtt ccaacttttt cttggcacgt gtagaaatct caacaccttc
    19021 taattgagca tggtcaacct cataccaaga ctgggtcttg accttctttt gatcgactgc
    19081 ctgatattcc agaccaagca ggccttttct agtcaaacgc atcatttcag cttgcttacc
    19141 taaatccaga gaagaaaagg ctagcgaatc ttctgaacca aacaggcgca ctcgttcttc
    19201 ctgactcaag ccttccagag gatagagaat cttgtcatag ctagaattca gaaatcccgg
    19261 aagcatggcc ttgaggatag agattttgta ggagaagaca gatttgcgta actcctcagc
    19321 cagccagagt tgttctggcg tgagaacagg agaaaaatcc agcacctctg caatatcttt
    19381 taaatcttgc tccatctctt ctccatctga ttgggactcc aaaccaaaaa caatcccttg
    19441 aatcaggcga ttacccttac caaaaggcac atgaacccgc atcccaactt ccagcattcc
    19501 ctcaaattcc tccggaatcc tgtaactata gggctggtcc gtctgcatca agggcacatc
    19561 tacgataatc ttagctaggg ccatcttctc acctcctcct tgtcagtaca ttcttgcaat
    19621 agaaaaaata agattgagtc cccccaacct taaatttttt caccatcttc tttttcttta
    19681 gcaatttgct ctttgatttt cttttcttct tcttctttgc ggcgtttttc ttcttcgata
    19741 cggcgacgca ctgcttcacg ttttccttct ggatctgggt gaattgtaac gtttcctgat
    19801 tcgatttctt ctaaagcgcg aagagttgat ttttcagact tgaaaccttg agttgctggg
    19861 gcacctgctt ccaattcgtg ggcacgtttt gcttccaaga ttacgagtga atattttgaa
    19921 ggaaccttgt cgagcaaggt atcaatagag ggttttaaca tcatttgctt gtacctattt
    19981 tctaaatttt atcgggtagt tggagatttt ggtaacatct cctgatagtg accaatgaca
    20041 cgatccacac agaagtgttc tgcttcaatc acacatttga cacgttcagc agctaggggc
    20101 acctgatcgt tgacaatcgc ataatcatac tcacgcatga gggcaatttc ttccttggcc
    20161 ttttcgattc gttgggcaat cacttctgca ctatctgttc cacgacctac caagcgatct
    20221 tgcaattcat ccaaatctgg tggtgtcagg aagataaaga cagcatctgg aacctttttc
    20281 ttgacctgaa gagcaccctg aacttcaatt tcaaggaaaa catcgattcc cttgtccaag
    20341 gtttcattga cataggtcag aggagttcca tagtagttgc cgacatattc tgcgtattcc
    20401 aacatctgtc cttgacgaat cagctcttca aattcttcac gagtacggaa gaaatagtca
    20461 acaccgtcca cttctccagg acgttgtgcg cgtgtcgtca tcgatacaga gtattgaaat
    20521 tggttttcag aactctcaaa aatctctctt ctaaccgttc cttttccaac ccctgaagga
    20581 ccagaaaaaa cgattagtaa gcctcggtct gccattgtgt ctccttttag tcaatctgtg
    20641 aaataacatt tctctagaat aatggcaaaa agccagatta tcctttacag tctttctatc
    20701 tagtgtaaca aaaaagcagt aatttttcaa ctgctctttc ttatttattt agcataatct
    20761 actgcacgaa gctcgcgaat cacggttacc ttgatatttc ctggataatc gagattgttt
    20821 tcaattttct tacgaacttt gtgagccaag attgtgactt tgtcgtcctt gatttttcct
    20881 ggattgacca tgatacgaat ttcacgtcct gcttgaaggg caaagctagt ttgcactcct
    20941 tcaaagccgt tagcaatttc ttccaaatca tggagacgct tgatgtagct ttcaagagac
    21001 tcactacgag cacctggacg ggctgcgctc aaggcatctg ctgcagcgac gataactgct
    21061 atcacgctct cagcttcaac atctccgtgg tgactagcaa tcgtattcac cacaactggg
    21121 ggttccttgt acttacgggc caattccata ccgatttcaa cgtggctacc ttcaacctca
    21181 tggtcaatgg ctttcccgat atcgtgaagg aatccagcac gacgggcaag agccgcattt
    21241 tcaccaagtt cgctcgccat gataccagcc aacttagcaa cctcaatcga atggcgcaaa
    21301 acattttgtc catatgaagt acggaactgc aaacgtccca taatcttcat caagtctgga
    21361 tgaaggtttg gcgcaccaat ttcataagca gcagcctcac cgtattcacg aatcttattg
    21421 tcaatctctt gacggttttt ctcaaccaac tcttcgatac gagctggatg tatacgacca
    21481 tctttgagca acatttccat agtcatacgg gcaatctcac gacgaatcgg atcaaatcct
    21541 gacaaggtca ccacttctgg tgtatcgtcg ataatcacat cgacccctgt caaactttca
    21601 aaggtacgaa tgttacgacc ttcacgacca ataatgcgtc ccttcatagt atcgtctggc
    21661 agatgaaccg ttgagtttgt tgactccgct acatattcac cagcgatacg ttgcatagct
    21721 tgaaccaaga tgtccttggc cattttgtca gagcgttcct tgacctcttg ctcagcttcg
    21781 cgaatgcgac tggcaatctc cctggtcaag ttttcctctg tctgagccaa gataatatct
    21841 cgtgcttctg cctgagacag agcaccaata cgctctagtt ctgcttcttt ttgtctttcg
    21901 acttcctcta attgctcttc acgcgcatca aggtttttcg ctctatcaga aatactttgt
    21961 tctttttgtt caagtgtttg ttctttactc gtcaaattgt cgtccttacg gtcaaggcta
    22021 gtagctctct ctgtcaaacg actttctatt tgtttgagtt cttgacgttc tgatttgaat
    22081 tcagcgtcca cttcttcacg gtattttctg gcttcttctt tggcctccaa tagtgcttct
    22141 tttttaagag acttgctttc acgtttggct tcattaacaa gtaaatccgc ttcacgctca
    22201 gcttgtccac gtaaattagt tgcttcttgt tcagcattta aaagcatcaa ctctgcagct
    22261 tcctgagatg atttcatctt agctgagatg ctgacatatc caatgactaa accaatgatg
    22321 acggcaaaaa cagcaatcgc aagcgacatg atttccatgt ttttacctca ttttattgtt
    22381 attccgaatg acatacattc ttttacattc taccataaaa aagtgatttt cacaaaccta
    22441 aaatagaata tgttttgggg aatttagtct gaattttagg attacacttc cttggttttt
    22501 taaggagata agtcagtgtc gctatcaaaa agttccaccg aatttctaca actatggatt
    22561 ttctattgtt gtgccaaata gtgttccact agattcaaat attttgcttt caagtctttg
    22621 aaaattcact ttaggaaatt acagcttatc ttcaagatca aatttgtcat aaattaactt
    22681 tttttattta gttgtatcaa tttatttctt aagtattaat ttatcct
//
LOCUS       DAVKMO010000030        22023 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVKMO010000030 DAVKMO010000000
VERSION     DAVKMO010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22023
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.030"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(161..1384)
                     /locus_tag="VW361_001314"
     CDS             complement(161..1384)
                     /locus_tag="VW361_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU9744348.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            1553..2875
                     /locus_tag="VW361_001315"
     CDS             1553..2875
                     /locus_tag="VW361_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9744349.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            2877..4763
                     /locus_tag="VW361_001316"
     CDS             2877..4763
                     /locus_tag="VW361_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU9744350.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            4931..5275
                     /locus_tag="VW361_001317"
     CDS             4931..5275
                     /locus_tag="VW361_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9744351.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLVEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            5285..6697
                     /gene="lacG"
                     /locus_tag="VW361_001318"
     CDS             5285..6697
                     /gene="lacG"
                     /locus_tag="VW361_001318"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU9744352.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            6767..8446
                     /locus_tag="VW361_001319"
     CDS             6767..8446
                     /locus_tag="VW361_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9744353.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPHGKV
                     INDTSAMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QPISFVLLSLMLVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(8571..10010)
                     /locus_tag="VW361_001320"
     CDS             complement(8571..10010)
                     /locus_tag="VW361_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9744354.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMNNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYIALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSIDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(10014..11363)
                     /gene="trkA"
                     /locus_tag="VW361_001321"
     CDS             complement(10014..11363)
                     /gene="trkA"
                     /locus_tag="VW361_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU9744355.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRITYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11551..12399
                     /locus_tag="VW361_001322"
     CDS             11551..12399
                     /locus_tag="VW361_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU9744356.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            12414..12962
                     /locus_tag="VW361_001323"
     CDS             12414..12962
                     /locus_tag="VW361_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU9744357.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            12969..13271
                     /locus_tag="VW361_001324"
     CDS             12969..13271
                     /locus_tag="VW361_001324"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744358.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDRTDEVS
                     SKHGFEVVDETDEVSNHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            13373..15055
                     /locus_tag="VW361_001325"
     CDS             13373..15055
                     /locus_tag="VW361_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744359.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETPELQSLFRLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEEQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            15040..15870
                     /locus_tag="VW361_001326"
     CDS             15040..15870
                     /locus_tag="VW361_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9744360.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            16063..16566
                     /locus_tag="VW361_001327"
     CDS             16063..16566
                     /locus_tag="VW361_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU9744361.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      16620..16854
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            17019..17582
                     /locus_tag="VW361_001328"
     CDS             17019..17582
                     /locus_tag="VW361_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9744362.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            17596..18222
                     /locus_tag="VW361_001329"
     CDS             17596..18222
                     /locus_tag="VW361_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9744363.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFQALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIEQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            18249..18638
                     /locus_tag="VW361_001330"
     CDS             18249..18638
                     /locus_tag="VW361_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU9744364.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDRISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            18643..19092
                     /locus_tag="VW361_001331"
     CDS             18643..19092
                     /locus_tag="VW361_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744365.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDWHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            19220..19807
                     /locus_tag="VW361_001332"
     CDS             19220..19807
                     /locus_tag="VW361_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU9744366.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            20197..21804
                     /locus_tag="VW361_001333"
     CDS             20197..21804
                     /locus_tag="VW361_001333"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU9744367.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
BASE COUNT         6560 a         3747 c         4852 g         6864 t
ORIGIN      
        1 taaaatgcag ctagaagaaa agttatttta atataaatca ctcaacatag agagaaggcg
       61 gtttcctata tggaagtcgt cttgttttca tattgtctaa atacgagata tctactacag
      121 gttatagttg atttaaacag gtctatagat ttctaatata ttaaggtgaa ataatatctt
      181 gtaatacatt gctatgttct atgaaaaaag cgacgatagc taatgcacaa gctcctatac
      241 ttccacgatg tttgttgtaa ggtaaaattt caatttctat attacgagta aagggaacga
      301 agtggagctg gtcttggatt ttatccctga cttcatgagt gaaaggttga taattaagca
      361 attgactgtt gatatagatt ttatcagcag gattgatgag gaggagattt gcaatagaag
      421 tggctaataa attgactcct ttatcaattt gttgacgtaa agcggagtcg cctaaattat
      481 aagccgttaa aagggtgtct aaatgaatgt ctttttcagt ctttacaagg ctttttagta
      541 cagttagttg ggaattttta aataataatt gggcgtgttt gattaaccaa gcatccgaaa
      601 tatatgtttg taaacaacct ttttttccac attcacaata ttgcccattc aattcgacaa
      661 tggtgtgtcc aatttctccg atataaggat ttttagaggc tcctattttt tcttttgtga
      721 aaaaggaagt gtaaatacct aatccagcgt gtaggaaaat aaagttatcg ggggtattgt
      781 gtggattaaa aaggtattgt cctatagcca tacaatcgat attatttttt acaataaaag
      841 gaaaattgaa tcttttaatt acatttaata aattaaaaga ttcccatatg gggttgtttg
      901 taatgatact tccggagtct ttgttataat gtccaggtat tgataagcca aatccaagta
      961 attttgtttc caaagggacg tactctatag ctgtttttat catattggta atggtggaat
     1021 tgatttctga aataggataa tcttcattca aaatttctgt ctcgaaaaga gttttccctt
     1081 gtaagtcaca tagactgaga aagataccta ggacgtttat ttcaatacct ccaacaacat
     1141 acggaatatt atctgtgata gaaatagttt ttctacgtct tccagatccg gaaaactcgc
     1201 taaattcatc accagtttcg tatatgaggg actgttcgct tagctctttt atgatgttag
     1261 tcgttgttgc tggagtaagt cctgtttcat taacaatatc tgtacgggat gttgctggat
     1321 ttcgatatag aaactccagt atagtggctc tattttgtaa aaaggctgat tgttttgtaa
     1381 tcatttgttt cctcctttgg tttattttat attaaacata agaaaaaatc aattaaaatt
     1441 attattctat acaaagaaaa aaatattgta aaaacaacaa aaaaatatat tgacaacgct
     1501 ttctgttagt ggtatattta atttataaaa aataaaaaaa ggagttccgg tgatgaacaa
     1561 tattttagcg tttttagaaa caaaagtcgc tccgtttggt gaaaaagttg gcaaccaacg
     1621 gcatttgaaa gctattcgtg aaggatttat gatggcaatg cctttgattt tagtcggctc
     1681 tttatttctt attctaatca gttggcctca agaggatttt acaaattggc tgaatagtgt
     1741 tggattgcta agtatcttga caactatgaa tcagtcaaca gtagcgatta tctccttggt
     1801 cgcttgtttc ggtattgcct acaggttgtc ggaaggatat ggtacagatg gtccgtcggc
     1861 agggatcata gccttatcca gttttgtatt gatggcacct cgtttttcga gtatggttta
     1921 tgataaaaat ggggagcagg tcaagcagtt atttggcggc gcaataccat tttctagcct
     1981 gaatgcatct tctttgttta tggcgattac tattggattg gttacagcag agatttatcg
     2041 tatgtttatc cagcgcggaa ttacgataaa aatgccaagt ggtgtcccag atgtggtaag
     2101 taaatcattt tcagctcttt tacctggctt tactactttt gttttgtggg ctctggtctt
     2161 aaaaggtctt gaagcggcag gagttgcagg aggtctcaac ggactcctag gtgcaattgt
     2221 tggaacaccg cttaagttaa ttgcaggaac gcttccaggt atgattctat gtgttattgt
     2281 aaactcattc ttttggttct gtggagttaa tgggggacaa gttttaaatg cttttgtaga
     2341 tccagtttgg ttacaattta ctacagaaaa ccaagaagct gtggctgcag gacaaacact
     2401 ccaacacatt attacattac cgtttaaaga tttatttgta tttattggtg gcggtggagc
     2461 gactattggt cttgcgattt gtctcttcct atttagtaag agtcgtgcga ataaaacatt
     2521 aggtaagtta gctattatac cgtctatttt taatatcaat acagctattc tatttacgtt
     2581 tccaacagtt ttaaatccga ttatgctgat tccgtttatt gctactccta caatcaatgc
     2641 cttaattacc tatgtatcaa tggctgtagg attagtaccc tacacaacag gtgtaatcct
     2701 tccgtggaca atgccaccga tcataggagg cttccttgcg acaggagcta gttggcgagg
     2761 agctctatta caagttgttt tgattttggt ttctgtagca atttattatc cattcttcaa
     2821 aattgcagat aaacgcaatc ttgaaaaaga aaaagctact gttggaggga aataagatgg
     2881 ttatcagagt atttgatcag cagaaaaata cttattctag ctttgcctta gaggaattaa
     2941 gttactatat aaatcgggtc tttaagactg acatagaact tgtcgaggag aaggaagcgg
     3001 atatttttgt aggattagtc aataaagagg atagaaaaga ccatgttctt atctcattag
     3061 acaagggtaa ggggagaatt gagtctaata caattgtagg tttacttatt ggaatttacc
     3121 gaatgtttca tgaatttggg gttgtgtata ctagaccagg gcgcggacat gactttgttc
     3181 cagagttacg atttgaagat tttttagata aagagctatc tatagatgaa acagccagtt
     3241 actatcatag gggagtatgt atagagggag cagattcatt tgaaaatata ctagatttca
     3301 ttgattggct acctaagatt gggatgaaca gttttttcat tcagtttgaa aatccctatt
     3361 cttttttgaa acgttggtat gaacatgagt ttaatccata cctaaataaa gaaaaattct
     3421 caaatgaatt agtacaagaa ttgagtgata ggttggataa agaattgcaa aaaagaggtc
     3481 ttattcatca tcgtgttggt catggatgga caggtgaggt tttaggttac tcttcaaaat
     3541 ttggctggga atcaggtctt agtatttcag aggagaagaa accgtatgtc gctgaaataa
     3601 acgggaaacg agaattattt aatacggctc cgattttaac cagtctggat ttttcaaatc
     3661 cagatgtggc ggataagatg gtagaaatta tcaaggatta tgccaagaaa agacctgatg
     3721 ttaactactt acatgtatgg ttgtcggatg ctcgtaataa tatttgtgaa tgcgaaaact
     3781 gtagacaaga attggtttcg gatcagtata ttcgtattct caatcaattg gatagggctt
     3841 taacgagtga gggattagat acaaagattt gttttctgct ttaccatgag ttgctatggg
     3901 cgcctcagaa agaaaaatta gataatcctg aacgctttac catgatgttt gcaccgatta
     3961 caagaacatt tgaaatgagt tatgcagatg tagattttga caattccata cctacgccta
     4021 aaccttatct gcgtaataaa attatacttc cgaattctct tgaggaaaat ttatcttatc
     4081 tttttgagtg gcaaaaaaca tttaaaggag atagtttcgt atatgactat cctttagggc
     4141 gtgctcatta tggcgattta ggctatatga aaattagtca aaccatttac agagatgtat
     4201 cttatctttc taacctacat ttgaacggtt acatttcgtg tcaagaatta cgtgccggat
     4261 tccctcataa ttttcctaat tatgttatgg gggaaatgct ctggaagaag acaagaagtt
     4321 atgaagaatt gattgaagaa tacttttctg ctttgtatgg gtcaaattgg cagtctgttg
     4381 ttgaatattt agaaaaatta tccagttatt cctcatgtga ttattttaat gcaattggca
     4441 gtcgtcaaaa tgatgtttta gcgaatcatt attatatagc ttacaatcta gctgataatt
     4501 ttttgccaat tattgaggaa aatatttcta agttattaaa tagtcaaaag gatgaatgga
     4561 aacagctcag ttatcatcgt gaatatgttg ttaagatggc gaaggcttta tatcttcaag
     4621 caactggaaa aacaaggcaa gctcaagatg aatggagaaa tgtgttgaat tatatccgtg
     4681 ggcacgaact gctattccaa tctaatttgg atgtttatcg tgtaattgaa gtagcaaaaa
     4741 attacgctgg tttccactta taaatcataa gtatagaaaa tgaaccaagg tattcagaga
     4801 agattgatcc taaatattat gaaatttaag gatttttaag atatttaggg tcaactttct
     4861 atttatatcg tagcgaagtc attttaataa tgatgtgtaa aagatggatc aagattgagg
     4921 aggaagaaag atgaaatcaa aagaagaaat aaatatgctt ggttttacaa ttgtcgctta
     4981 cgcaggagat gcaaggtcag atttgatgga tgctttggcg tttgcgagag atggatattt
     5041 tgaacaggca agagaattgg ttgagtctgc aaacgactca atagtgtctg cccatcgaga
     5101 acagactaat ttattagtgg aggaggcatc tggagataat tttgaagtga gttttatcat
     5161 gattcatggt caagatacct tgatgacaac gatgctattg tatgatcagg tcaagttttt
     5221 tattgatgaa tatgaacgaa ttcgaaagat tgaagaacat attggtttgc aatgaggatt
     5281 agtcatggaa aatttacagg ttaaagcctt accgaaggag tttttattag gagctgctac
     5341 cgctgcttat caagtagagg gtgcaactag ggtagatggc aaaggaacaa atatgtggga
     5401 tgtttatttg caagaaaaca gtccgttctt accagatcca gctagtgatt tttattatcg
     5461 ttacgaagag gatatagctt tggcggcaga acatggtttg caggctttgc gtttatctat
     5521 ttcttgggtt cgtatatttc ctgatataga tggggagcct aatatattag ctgttcgtta
     5581 ttaccataga gtctttcagt cttgcttaaa acataatgtg attccgtttg tttctttaca
     5641 tcattttgat tcgcctcaga aaatgttaga aacaggggat tggttgaata gagagaatat
     5701 tgatcgtttc atacgatatg ctcgcttttg tttccaagaa tttacagaag tcaagcattg
     5761 gtttacaatc aatgaactga tgtctcttgc tgcaggtcaa tatataggag gtcagtttcc
     5821 tccaaatcat cattttcaat tatctgaagc aattcaagcg aatcataata tgttgttggc
     5881 gcatgctctt gcagtcctcg aatttcatca attaggaatt gagggagaga taggttgtat
     5941 tcatgcttta aagccaggct atcctattga tgggcaaaaa gaaaatattt tagcagctaa
     6001 acggtatgat gtttataata ataaatttct attagatgga acttttttgg gctactacag
     6061 tgatgacacg ctttttcact tgaatcaaat attggaagct aataattcta gctttattat
     6121 tgaagatggt gatttagaaa ttatgaaaag agctgcacct cttaatacga tgtttgggat
     6181 gaattattat cgttcagaat ttattcgtga atacaaaggt gaaaatagac aagaatttaa
     6241 ttcaacagga ataaaaggac agtcttcttt taaattaaat gctctaggtg aatttgtaaa
     6301 aaagcctggt attccgacaa cagattggga ttggaatatt tatcctcaag ggttatttga
     6361 tatgttgctt cgtatcaaag aagaatatcc tcaacatccg gtcatttatt taactgaaaa
     6421 tggtacagcc cttaaagagg ttaagccaga gggcgagaat gatattattg atgacagtaa
     6481 aagaatccgt tatattgagc aacatttaca caaagtttta gaggctcgag ataggggagt
     6541 caatattcaa ggctatttta tatggtcttt gcaagatcaa ttttcttggg cgaatggcta
     6601 caataagcga tatggtcttt tctttgttga ttatgaaaca cagaagagat atattaagaa
     6661 aagtgctctt tgggtaaaag gattaaaacg gaattaaggt tagcgatttg actgatgttt
     6721 aatatatttt aactatgagc ttaaattttt tacaggagga gtttttatgg ataagttagt
     6781 cgctgccatt gaaaagcaac aagggaaatt tgaaaaaatt tctactaata attatatgat
     6841 ggctattaaa gatggattta ttgctactat gcctttaatt atgttttcaa gctttttgat
     6901 gattattatt atgattccta aaaatttcgg agtagagtta ccgagtccag ctattgcctg
     6961 gatgaggaaa gtgtatatgc taaccatggg agttttgggt attattgttt cagggacagt
     7021 tgcaaagtca ttggctggaa atgttaacag aaaaatgcct cacggaaagg taataaatga
     7081 tacttctgca atgttggcag ccatatgtag ttatctggta ttaactgtaa cgcttgtagt
     7141 tgatgagaag acgggatcta caagtttgtc gacaaactat ttaggatctc aaggattgat
     7201 aacttcgttt gtcagtgcct ttattactgt aaatgtttac cgattctgta ttaagcgaga
     7261 cattactatt catttaccta aggaagttcc tggggctata tcacaagctt ttagagatat
     7321 ttttcctttt tcttttgttt tacttattag tggtttgtta gatattgtat ctcggtttag
     7381 tttagatgtt ccttttgccc aagtatttca acaactattg actcctattt ttaagggggc
     7441 agaatcatat cctgctatga tgttgatttg gtttatgtgt gctttgcttt ggtttgttgg
     7501 aattcatgga ccatctattg tcttacctgc tgttacagct ttacaactga gcaatatgga
     7561 agagaatgct caacttcttg caaatgggca gttcccttat cattctttaa cacctaattt
     7621 cggaaattat atcgctgcta ttggaggaac gggggctacc tttgttgtac catttatttt
     7681 gattttcttt atgcggtcta aacaattaaa atcggtaggt aaagctacaa ttactcctgt
     7741 tttatttgcg gtaaatgaac ctcttctatt tggtatgcct gttattttga atccctatct
     7801 ttttgtccct tttttgatga ctccaccagt gaatgtattt ctaggaaagg tatttattga
     7861 tttctttgga atgaatggat tttatatcca gttaccttgg gcctttcctg gtcccttggg
     7921 attgttaatt ggaacgaatt ttcaacctat ctcctttgtg cttttatctt tgatgttagt
     7981 tgtcgacata ttgatttatt tgccattctg tagagcgtat gatagacagt tactgatgaa
     8041 agaagatgtt gcaagctcaa atgatattat tttagaggag gatacaagtg aaataatgcc
     8101 tggtgagata gatgtaataa aaagtaagga gttgaaagta ctggttcttt gtgcagggtc
     8161 tggaacaagt gcgcaattag ccaatgcaat taacgagggc gctcaattag cagaagttag
     8221 agtgattgcg aattcaggag cgtacggagc tcattatgat attatgggtg tttatgattt
     8281 aattattctg gctccacaag ttcggagtta ttatagagag atgaaggtgg atgcagaaag
     8341 attaggtatt cagatagttg ctaccagagg aatggaatat attcatttaa caaagagtcc
     8401 aagtaaatcc ttacaatttg tattggagca ttaccaagct gtgtagtaag tttttccatc
     8461 ttttatttga gtaaggactt tgcttacaga caggcttgga tttaaaaacg ttcccccttt
     8521 ttaatataaa aatccctctt tcacaattgt aaaaagaggg attttgtatt ttatctctta
     8581 gaccaagttc tcttcataaa gagaaggagg attgggtaaa tctccaagcg gcctgcaatc
     8641 attgcaaagg agaggagaat ttttgagata ggactaaaga ttgagaaact agaagtggtt
     8701 cctagaatag gcccgatatt attgaaacag ctaaagacag cgctggtcac gatcagaaaa
     8761 tcattgctat ctatgctgac aataaagata agggatagca aaatcatagc atagatgaca
     8821 aagtacttga gaatcttatg ctgggtatct ttatcaatca ccgtttgatt cacatggagg
     8881 gtcaaaacac ggtggggcga taggattgac aaaatttggt ttttggcaat ttttgaaagg
     8941 atgaggcctc gaataatctt gagtccacct gcagttgatc cagcagagcc accgattgtc
     9001 atgaggaaga ggaggataaa ctgggagaag aggggccagt tggtaatatc tccatatcca
     9061 aaaccagttg ttgtaatgat gttggaaacc tggaagaagg ccatttcaaa gctctttgaa
     9121 aaccctgggt agaggtagag ggtgttgagg ctaatcaagc ctgtagaaac cagcacgatg
     9181 accaagtaag cccgaagctc ttcatctcca aagaaggcct taacccgacg gagcataagg
     9241 tagtagtaga gattgaaatt taccccaaaa accaaaactc ctatactaac cagataggta
     9301 atcagtgagc taccatagtg ggcaattcca tcgttataga cggtaaatcc tccagttccc
     9361 gctgtcccca tagcaatgac aaaactatcg tagagaggca taccggctag ataatagatg
     9421 atgacaaaga gggaaaagag ggctatgtaa aggagataga ggatctgggc agtgtttttt
     9481 aatttggata caaccttgcc aaaaacagga cctggaacct cagccttcat cacctctagg
     9541 tggctatttt tggcattgtt cataatagca agtgcaaaaa caagcactcc catccctcca
     9601 atcaagtggg taaaacttcg ccagaagagg agggaacggc tgagaaccga aacgtcgttc
     9661 aaaatacttg ctccagtagt tgtaaaccca gaactaattt caaaaaaggc atcaataagg
     9721 ctggggattt gcccagaaaa gacaaagggg agaccaccaa agaaagacca aaggatccaa
     9781 cagagggcaa cgatcaagac tccctccttg gcataaatcc gttgattttt tggcttctgt
     9841 aaactccctg aaccgcctaa caatacgaga atccctatgg tcgaaaagag ggctgtaaag
     9901 acttggctcg attcacggta atagacagcg atagccacag gaaccaagag gagaacagct
     9961 tcaatcaaaa gtaactttga aaggaggtaa cgaatcatac ttttattcat ttcttacctc
    10021 gcaatcaagt cataaatctt ggtgatgttt ggcaacaagg ttgttactag gagcttgtct
    10081 ccaacttcca acatatcctc cccagttggg aaaatagtct tgccctttcg aataatggct
    10141 gcaataagaa cccctttttt caatttcagt tgagaaagag gtttggcagt cattttattg
    10201 gcttccttga tatggaattg cagggtttcg atttggccat tggctagatg gtgcatggct
    10261 tgaaggtctg aatactgggc attaactcga ccacgaataa agtgcataat cgtatctaca
    10321 gcgatgcttt taggtgtgat gatacttgaa aaatcaggcg cattgataat ctcgaggaga
    10381 ctggtacgat tgaccttagt aatatttttc tgtacaccta ccctgtcaag gaacatagat
    10441 gtaatcagat tttcctcatc gactcctgtt agagtcgcaa cggcatcata gtgttgagca
    10501 ctttcttcca gcaggatatc ttttgcggtt ccatctcctt gaacgatgta gagatttggg
    10561 aatttctcgc taaagaagct ggcgatttca ggattgattt caatgacttt tgtatcgata
    10621 cgactatctt tgagaatacc aagtagataa taggtaattc tacctgctcc aacgatgaga
    10681 aggctcttca cggcgcgtga tttaaaataa ttatggaaga gtatcatatc gacacggtta
    10741 ccagtgacaa agattctatc tttatcctgt acagtcatgt caccgcttgg aatgataatt
    10801 tgatgatccc tctctatcgc acagacaatg acattaccaa attttttacg aaaatcagaa
    10861 atgggcattt ggcaaagacc gctggtggac ttgacgacaa attccatgag gctaacgcgt
    10921 ccaccagcaa agcgttcgac agacagggcg ttggggaagt caatgatatt cgcgatagcg
    10981 cgggcagcca agagctcagg attaacgata agagaaaaac cgagaatatt cttttccttg
    11041 aaataagagt tagaatattc agggttccgc acccgaacga tagtttcttt agctcccatt
    11101 ttcttggcta gaactgctgc aatcatgttg acttcatcgt gctcagtcag ggcgataaag
    11161 atatcacaat cttggacgct ggcttgctca agaatggcaa aatcggcccc gttaccaagg
    11221 ataccaatga tatcaaagcg actgacaata tgattgagaa cagcttcgtc ttgctcaatc
    11281 agcaaaacat catgcttttc tgcaaccaag gagcgacaga gggcaaaacc aacttttccc
    11341 cctccgacaa ggataatttt cataataaaa cctacttttt catgatgtaa ctatcatacc
    11401 ctttttcaag aaaaaatgca cctactagct aataacaaga gcttttagtg aaaattcgct
    11461 ataaggtaaa actataccct aaccaattga aatagctatt agcgactttc tctgaaatat
    11521 ggtatgataa aggatataca aggagataaa atgaataata atttactggt attacaatca
    11581 gactttggtc tggttgatgg tgcggtatcg gctatgattg gagtggcttt agaagagtct
    11641 ccaaccttaa aaatacatca cttgacgcac gatatcacgc cttataatat ttttgagggg
    11701 agctatcgtc tctttcagac ggtggattac tggcctgagg gaacgacgtt tgtatcggtt
    11761 gttgatccag gtgtcggttc gaaacgtaag agtgtagttg ccaagactgc aaaaaatcaa
    11821 tacattgtca cgccagataa tgggacgctt tcctttatca agaaacacgt tggcattgta
    11881 gccattcgtg agatttctga ggtggccaat aggcgtcaaa acacagagca ttcttatacc
    11941 ttccacggtc gtgatgtcta tgcctatact ggtgctaaac tggccagtgg tcacattact
    12001 tttgaggaag tagggccaga gctcagtgtg gaacagattg tagagcttcc agtcgtagcg
    12061 accatcatag aagatcatct ggtgaaggga gccattgata ttctggatgt gcgtttcggt
    12121 tcgctttgga cctctatcac acgggaagaa ttttacaagc tggaaccaga atttggtgat
    12181 cgttttgaag tgaccatcta tcatgctgat atgctggtct atcaaaatca ggttgtctat
    12241 ggcaaatcat ttgcagatgt gagaattggg caacccatcc tttacatcaa ctctctctat
    12301 cgtttaggtt tggctatcaa ccaaggttcc tttgccaagg cctataatgt aggtgtcggt
    12361 tcatcttgga ccattgaaat aaagaaaata gaaggataaa ataggagaat agtatggaaa
    12421 tcaaatttac aattaaacaa gttgttgctg tcggaattgg cgctgccctc tttgtcgtca
    12481 tcgggatgat caacattcca acccctgttc caaatacaag catccagctt cagtatgcgg
    12541 tacaagcgct actttctatt atttttggac cgattatcgg tttgcttgtc gggttgattg
    12601 gtcatgcaat caaggactct cttgttggtt atggtctatg gtggacttgg attatcgcta
    12661 gcggactctt tggtttagtt gtgggacttt ttagaaagta cgttcgcgtg atcaatggtg
    12721 tttttgactg gaaagatatt cttattttta acctcattca actacttgca aatgcccttg
    12781 tttggggtgt cttggcacca cttggagatg ttgtgattta tcaagaagcg gcagaaaaag
    12841 tatttgcaca agggattgtt gcgggaattg ccaatggtgt atctgtagct attgcaggaa
    12901 ctcttctctt acttgcctat gcaggaaccc aaactcgtgc aggaagtttg aaaaaggact
    12961 aatactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggttgc tcaaaacagt
    13021 gttttgagat tgtggataga actgacgaag tcagctcaaa acatggtttt gaggttgtgg
    13081 atagaactga cgaagtcagc tcaaaacatg gttttgaggt tgtagatgaa actgacgaag
    13141 tcagtaacca tacctacggc aaggcgaagc tgacgtggtt tgaagagatt ttcgaagagt
    13201 ataaaatgat ggggaaggct gggcaactag tctttttcga tgtttataga ttagttaggc
    13261 aagtaagcta ggataggaat ctttttggcg ctaagatttt aagagaagag actgcaagaa
    13321 gggcttgatt tatgataaaa tagaagtcta agaagcgaat gaagagagta agatgaaaga
    13381 agctataatt gagtggaagg atttctcttt ccggtatgaa acacaacaag aaccgacctt
    13441 gcaagggata gacttgacca tttacaaggg agagaaagtc ttaattgttg gaccatctgg
    13501 atcaggtaaa tctaccttgg gtcagtgttt gaatgggatt attcccaata tttacaaggg
    13561 tcagacatat ggagaatttt tgataaaggg tcaagtagcc tttgatatga gcatctatga
    13621 taagtctcat ctggttagca cagttttgca ggatacagat gggcagttta ttggcttgtc
    13681 tgtggcagaa gatttggcgt ttgctctgga aaatgatgtg acagccctag atgagatgaa
    13741 aggtcgtgtt tataaatggg ctgaaaagct ggaccttctt cctttactgg atcagcgtcc
    13801 tcaggatttg tcaggtggac aaaagcagcg agtcagtctg gctggtgtct tgattgatga
    13861 aagtccgatt ctcttgtttg atgagccact cgccaatcta gatcccaagt caggtcagga
    13921 tattatcgaa ttgattgacc agattcataa ggaagagggg acgacgactc tgattatcga
    13981 gcaccgtttg gaggacgttc tgcatcgccc tgtggatcgg attgtcttga taaacgatgg
    14041 tcgtatcctt tttaatggga gccctgacca gttgcttgcg actgatttat tgactcaaaa
    14101 tggaattcga gaaccccttt atctaaccac tctccgtcaa ttaggtgtgg acttagtcaa
    14161 ggaagaacaa ttagcagatc tggataactt gtctatctca aaagggcaag tccagttaca
    14221 gacggaactg gtaaaagaaa ccccagaatt gcagtcactc tttagactag aggacgtgtc
    14281 tttttcttat gatgatagac cgattttaaa atccctacat ttagatatta aaaagggtga
    14341 aaagattgct attgtcggaa aaaatggagc agggaaatca actctagcca aggctataag
    14401 tagctttatt cagacggaag gacgctatct ttgggaagaa caggatataa aaggcgattc
    14461 tgttgcagag cgggcggaac gagtaggcta tgtgctacaa aatcctaatc aaatgatttc
    14521 aaccaatatg atttttgatg aggtggctct agggctccgt ttgcgaggtg tggatgagaa
    14581 ggaaattgaa acgagagtct atgaaacctt gaaaatctgt ggactttatg aattccgtaa
    14641 ttggcctatt tctgccctgt catttggtca gaaaaaacgt gtcaccattg cttcaatttt
    14701 ggtcttagga gctgaaatta ttctcctaga tgaaccgact gcaggtcaag atcagaagaa
    14761 ctatactgag attatggaat ttctcgaaga gttacatcaa aaagggcata ccattgtcat
    14821 gattacccat gatatgcaat tgatgctgga ttattcagac cgggtccttg tcatggtgga
    14881 tggagaattg attgccgata ctgttccagc cagtctgttg agcgatcctg agctgttagt
    14941 aaaagccaat ctaaaagaaa cctccatctt taacttggct aagaaactag atgtggatcc
    15001 actggattta acggcatttt acaaagaaag gagagaggga tgcaagctaa attaatcggt
    15061 taccagcata gagatactgt gattcatcgc ttgtcaggag ctgggaaact tctctttttc
    15121 attctggtat cattggcggc catgattagc tatgatacca gaatgctctt gctgattgcc
    15181 atcttttcag tctttctcct ctatttatca gaaattcgct ttaaagatgt ttcctttgta
    15241 gccgtttttg cgacggtatt tgccgtttta aacgttttga tggtctatct cttttctccc
    15301 gagtatgggg ttggacttta tggagagaga agtgtgattt ggcagggaat cggtgtctac
    15361 actctaacca gccaggagct cttttatctg ctaaatttgg ccattaagta tctttgcacc
    15421 attcctctgg ctattatctt tttgatgaca acccatccta gtcagtttgc ttccagttta
    15481 aatcaaattg gtgtgcccta taagattgct tattctgtca gcctgacctt gcgctatatt
    15541 ccagatttgc aggaagaatt ctttactatc aagatgtctc aggaggcgcg tgggatggaa
    15601 ttatccaaga aagcttctct tatgcaacga atcaaaggca atctgctcat tattacgccc
    15661 ttgattttta gctcgctaga acgcattgat accattgcga ctgccatgga gcttcgccgc
    15721 tttgggaaag agaaaaaacg cacatggtat agttatcagg ccttgaaaaa aggagactat
    15781 attaccttgc tcttggcaac cttgttttta gtagttagtt tactacttat cttgcagaat
    15841 cagggacgat tttacaaccc ttggaaatag cttgaaaaaa ttgaaaaaat caagtcattt
    15901 ctattgacaa tgattctgaa agtgttatac taagaaagta gtttcgctga tttacttcaa
    15961 acctgttgtg aggtaagtta acgatgcctt aaccacgctg tttgctgagc ttgactccgg
    16021 gcagtgtggc tatttttttg caatggtgaa aggaagcaag tcatgacaaa tcacattgta
    16081 ttatttgaac ctcaaattcc acaaaataca ggcaatatcg cgcgtacttg cgctgcgacc
    16141 aattctcccc tccacatcat caagcctatg ggctttccta ttgatgaccg caagatgaag
    16201 cgggctggat tggattactg ggataagcta gagatttatt tttacgagag tttagaagat
    16261 ttcatatctc agatgaaggg aaaactctat ctgatttcga aattcgcgga aaaaatctat
    16321 tctgaggtgg atttatcgac tgacgaggac cattattttc tctttggacg tgaagacaag
    16381 ggcttacctg aagattttat gcgagaacat cctgagaagg ctctccgtat tcccatgaat
    16441 gatgaacatg tccgcagtct caatgtgtct aataccgtct gcatgattgt ctatgaggct
    16501 cttcgccagc agaactttgc aggtcttgag ctcgtccata cctatgaagt ggataaattg
    16561 aaataaaaaa tgaaaatgaa caaaatgctt gcgcttgcaa gcgttttttg ttatgataaa
    16621 agagtcttca gggcagggtg tgattcccga ccggcggtga ctttaactag gaaatgatct
    16681 tttcctttta tactttgttg acaagctttg cctaaccaga agttatgcct acagcttgtc
    16741 gcctagtcta aaagaaaaat ctctatttct ttctctttaa agaagtccgc gagcgcaagc
    16801 tgatgtggtg agattccaca accgacagta tagtctggat gggagaagac gaaagaatag
    16861 ctttgtctgt tttgatagat ttatagccgg attgtaacca cttgctttgt ttttctttaa
    16921 tagagtaaga gggaactttt gggatataaa aagtgagaat agatagagga atcctttcca
    16981 acttcttctg attttataga aaattggagg aacctgttat gacaaacaca cgtcgacttt
    17041 cgaccattgc aattctatca gccatctcat ttgtgctgat gtactttgac tttccgcttt
    17101 taccagcggc atctttcctc aagatcgaat ttagtatctt gccagtcctt gtgggtctgg
    17161 tggtcatgga tttgcctgct gctctaggag tgctcttgct tcgctcactc ttgaagttgc
    17221 ttcttaacag ccaaggagtg aatacttaca ttggtttgcc gatgaatatc gtagctttgg
    17281 gagtttttgt catcgtattt gctttgattt ggaaaaagga acggacaacc cttcgtttcc
    17341 tactaggctc tctagctgga actattggtt taaccttggc catgttggtt ctcaactatg
    17401 tttatgctgt tcctttgtac gctaagtttg ctaactttga tattggaaaa attttgggac
    17461 tttccaacta cctaatgacc atggtattac cttttaactt gattgaaggt gttatctttt
    17521 ccgtttcatt ctggttgttg tacgtccttt tgaaaccaac cttaaaacac tatgaaagat
    17581 aaacaaacat ttttaatgaa gggcagtttt gcccttttac ttttcgttat tcttggctat
    17641 atggtcaaat tttaccctga aatgttggtc aattttgacc aatcgattca gactgccatt
    17701 cgaggagact taccagatta tttgactatt ctttttcaag ccctcacacg tctgattgat
    17761 atcccagtga ttatcacttg ggttgtcatt acagcttttg tcttttatcg taagcgatgg
    17821 aagatagaaa gtttcttcat gctgggaaat ctggctttgg caggtctttt aatcgtgacc
    17881 tttaaaaata tctaccagcg cccacgacca gctattttac atctggtgga ggagaaggga
    17941 ttttccttcc caagtgggca ttctctagct gtaacgctga tggtagggac tttgattgtt
    18001 attcttagtc agcggattaa agatcaggtc tggagaaaaa tcgaacaaat cgtccttggc
    18061 ctctacctag tcagtgtgct ggtatcaaga gtctatctgg gagttcatta cccatcagac
    18121 gtccttgcca gtctctgtgt gggcttggga gtcctgttta tcgagtttcc cttttatgac
    18181 aagctccgct tccaatggcg atttaaaggc aaacagaagt gagtatcgaa ttcccttgag
    18241 agaaagaaat gaaagtcaat atagcagatc ttcatccgac tcaactatat ttatcagaaa
    18301 agaagttgca agatattcag atgctttacc agtcggcaga aacaatccaa gtcgatcgaa
    18361 tcagtattct tgcctttgga gattgtttgc tgattacaga tgggcatcac agggcttatc
    18421 aggctttatt ggcaggtcgg gatacgattt ctgctgagtg ggatagagat ggtggtgatg
    18481 aactatatca tctctatgcg caagcttgcg aggaaagaaa gatttactct gtttttgatt
    18541 taaaagatcg tatcctagct caagatgggt atgaagcaaa atggtataac tggtgtgatg
    18601 gttttaatca agcagcaact cttttgttga aaaggtagtg cattgtgttt tgttccttat
    18661 tataaggtca atcattgtga ggaagctttt gcttggtatc aggatgtgaa cttggtttac
    18721 ctcgtagatg gggtgaagct tccttacagt caagcgacct tggaagccat gtattcctat
    18781 ttggattggc atggtgagct tttttggatt gaagtcaagg agaagggaga atggtttcca
    18841 attggggata ttacactatc tcaggataat ctccccattg tgattgggaa ttccgcttac
    18901 caacatcgag gacttggaaa aaagattcta agtgctttga ttgaattggc tcgagtaaaa
    18961 ggatggaaag aattgagagt caaggaaatc tacacctaca atcatgcttc taggaggtgt
    19021 ttcaagtcgc ttggatttgt ggaaaatgga gcaacagaaa aaggaaggag ttttatattg
    19081 gaattagtct aatcctgcca ctttctcccc cttaaccttt gactattccg caaaattatc
    19141 gtaaaataaa gagtaaatga taaaatgagg tcagagtctg ttcgctctga caatagtagt
    19201 ataaatgagg agaaacgctt tggaattaga agtatttgct gggcaagaaa aaagtgaact
    19261 atctatgatt gaggtagcgc gtgctatctt ggaacttcgt ggtcgcgatc atgagatgca
    19321 ttttagcgat cttgtaaacg aaattcaaaa ctaccttgga acatcaaaca gcgatatccg
    19381 cgaagctttg cctttgttct acacagagtt gaactttgac ggtagcttca tctcacttgg
    19441 ggacaacaaa tggggtcttc gttcatggta tggtgtggac gaaatcgacg aagaaatcat
    19501 cgctcttgaa gaaaatgacg acgatgaagt agcaccaaaa gctaagaaaa aacgtgtcaa
    19561 tgcctttatg gatggtgatt cagatgccat tgactacaat gcagatgatc cagaagacga
    19621 agatgcatac gaagcagatc cagctctttc atacgatgat gaaaatccag atgatgaaaa
    19681 aaatgaagtg gaagcttatg atgcagaaat caacgaaatc gctccagatg acttgggaga
    19741 agatgtggat ctcaacgaag acgacgacga gttttcagat gacgacgctg aaaccagcga
    19801 ggaataagag ttagctattg acaattatcc tatttttagg tatcatattg tttgggcacc
    19861 tcttttagag gtcggggctc cctagttctt agggagctat ttttgttttt tcaagaagtt
    19921 atcttcttgt attttatact caatgaaaat caaagagcaa gctaggaaac tagccgtagg
    19981 ctgctcaaaa cactgttttg aggttgtaga taagactgac aaagtcagga acacatatct
    20041 acggcaaggc gacgttgacg cggtttgaag agattttcga agagtattag ttgtgaatct
    20101 ggtgcagtcg tcccagatta ttcttattag tagggtcttg ttttctatat cccctcgtag
    20161 ttaacaagac cttgagcatt ttagaaagag gaatctatgt ctacgaaata tatttttgta
    20221 actggtggtg tggtatcgtc tattgggaaa gggattgtgg cagcgagtct aggccgtctc
    20281 ttgaaaaatc gtggtctcaa agtaaccatt caaaagtttg acccttatat caatattgat
    20341 ccgggaacca tgagtcctta ccagcacggg gaagtttttg tgacagatga cggagctgag
    20401 acagatttgg acttgggtca ctatgaacgt ttcatcgata tcaatctcaa caaatattcc
    20461 aacgtgacaa ctgggaaaat ttacagtgaa gttcttcgta aagaacgccg tggagaatac
    20521 cttggggcaa ctgttcaagt cattcctcat atcacagatg ctttgaaaga aaaaatcaag
    20581 cgtgccgctc taacgaccga ctctgatgtc attatcacag aggttggtgg aacagtagga
    20641 gatatcgagt ccttgccatt cctagaggct cttcgtcaga tgaaggcaga tgtgggtgcg
    20701 gataatgtca tgtatatcca tacaaccttg cttccttacc tcaaggctgc tggtgaaatg
    20761 aaaaccaaac caacccaaca ctctgtcaaa gaattgcgtg gcttgggaat ccaaccaaat
    20821 atgttggtta ttcgtacaga agagccagct ggtcaaggaa ttaaaaataa actggcccag
    20881 ttctgtgatg tggcaccaga agccgttatc gaatcgttgg atgttgaaca cctttaccaa
    20941 attccactga acttgcaggc acaagggatg gaccaaattg tttgtgatca tttgaaatta
    21001 gacgcaccag cagcggatat gacagaatgg tcagccatgg tggacaaggt catgaacctc
    21061 aagaaacaag ttaagatttc ccttgttggt aagtatgtgg agttgcaaga tgcctatatc
    21121 tcagtggtcg aagccttgaa acactctggc tatgtcaatg atgtagaagt taaaatcaat
    21181 tgggtcaatg ccaatgatgt gacagcagag aatgtagcag aactcttgtc tgatgcggac
    21241 gggatcatcg taccaggtgg ttttggtcaa cgtggtacag aagggaaaat ccaagccatc
    21301 cgctatgcgc gtgaaaatga tgttccaatg ttgggagtct gcttgggaat gcagttgaca
    21361 tgtatcgagt ttgctcgtca cgttttaggt cttgaaggtg ccaattctgc agagcttgca
    21421 ccagaaacaa aataccctat cattgatatc atgcgtgatc agattgatat tgaggatatg
    21481 ggtggaaccc ttcgtttggg actttatccg tctaagttga aacgtggctc taaggctgct
    21541 gctgcttatc acaatcaaga agtggtgcaa cgccgtcacc gtcaccgtta tgagtttaat
    21601 aacgccttcc gtgagcagtt tgaggcagca ggctttgtct tttcaggagt ttctccagac
    21661 aatcgtttgg tagaaatcgt ggaaattcct gaaaataaat tctttgtagc ttgtcagtat
    21721 caccctgaac tgtcaagccg tccaaaccga ccagaagaac tctacactgc ctttgttact
    21781 gcagcggttg agaacagcaa ttagcaaaat cagaaccttt gagaaaaatc tcagaggttt
    21841 tttgcatacg atgatattgc agtatatctg aggtaggggt cctctgtatg tacctgctac
    21901 cgttgaaatc aatagcgact ccctcttgcc ctgtgctagt gaatggattt atcagtatat
    21961 tgaaatgaaa taaaatttga acaaattaat tcggaaagcc aaatcaattt ctagcaaagt
    22021 ttt
//
LOCUS       DAVKMO010000031        21603 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVKMO010000031 DAVKMO010000000
VERSION     DAVKMO010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21603
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.031"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            110..763
                     /locus_tag="VW361_001334"
     CDS             110..763
                     /locus_tag="VW361_001334"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU9744368.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            773..1237
                     /locus_tag="VW361_001335"
     CDS             773..1237
                     /locus_tag="VW361_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9744369.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTADLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1250..2518
                     /locus_tag="VW361_001336"
     CDS             1250..2518
                     /locus_tag="VW361_001336"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU9744370.1"
                     /translation="MLLIKNGHVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFKAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2532..2792
                     /locus_tag="VW361_001337"
     CDS             2532..2792
                     /locus_tag="VW361_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744371.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2803..4164
                     /gene="pdrM"
                     /locus_tag="VW361_001338"
     CDS             2803..4164
                     /gene="pdrM"
                     /locus_tag="VW361_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU9744372.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4318..5286
                     /locus_tag="VW361_001339"
     CDS             4318..5286
                     /locus_tag="VW361_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU9744373.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDFNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAIDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5302..6294
                     /locus_tag="VW361_001340"
     CDS             5302..6294
                     /locus_tag="VW361_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU9744374.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            6513..7556
                     /locus_tag="VW361_001341"
     CDS             6513..7556
                     /locus_tag="VW361_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU9744375.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMNLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7620..9305
                     /gene="lpdA"
                     /locus_tag="VW361_001342"
     CDS             7620..9305
                     /gene="lpdA"
                     /locus_tag="VW361_001342"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU9744376.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGSASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDNIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9369..10358
                     /locus_tag="VW361_001343"
     CDS             9369..10358
                     /locus_tag="VW361_001343"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU9744377.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10423..11493)
                     /gene="xerS"
                     /locus_tag="VW361_001344"
     CDS             complement(10423..11493)
                     /gene="xerS"
                     /locus_tag="VW361_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU9744378.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLKSGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(12077..13627)
                     /locus_tag="VW361_001345"
     CDS             complement(12077..13627)
                     /locus_tag="VW361_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU9744379.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHMIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGSGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13643..14422)
                     /locus_tag="VW361_001346"
     CDS             complement(13643..14422)
                     /locus_tag="VW361_001346"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU9744380.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(14409..15260)
                     /gene="ylqF"
                     /locus_tag="VW361_001347"
     CDS             complement(14409..15260)
                     /gene="ylqF"
                     /locus_tag="VW361_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU9744381.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15479..15655)
                     /locus_tag="VW361_001348"
     CDS             complement(15479..15655)
                     /locus_tag="VW361_001348"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9744382.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(15707..21568)
                     /locus_tag="VW361_001349"
     CDS             complement(15707..21568)
                     /locus_tag="VW361_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9744383.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTKLINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSEAVVTDKG
                     EPAVQPELPEAVVSDKGVPEVQPALSEAVVTDKGETEVQPESSDTVVSDKGEPKQVAP
                     LPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVKPTEETPVNPNEGTTEGTSIQGAEN
                     PVQPAEESTTNSEKVSPDTSSENTGEVSNKPSDSKPPVEESNQPENSGNTTSENGQTE
                     PEPSNGNSTENVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLELRNVSDLELYS
                     LSNGTYKQHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKV
                     EKLQQEIESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNLSGTYHLGASLNANE
                     VELSTDDKSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFESLRGATIEKLSLKNVSISG
                     KDDIGSLANEAQNNTKIKQVHVDGVLAGERGIGGLLAKADQSSITESSFKGRIVNTYE
                     TTASYNIGGLVGHLTGSKASLTKSKATVVISSNTNSSDQTVGGIAGLVDKDAHIQNSY
                     SEGDINNSQRFGKVAGIAGNLWDRESNSENHAGRLTNVLSDVNVTNGNAISGYHYNGM
                     KITDAFSNKANKVFNVTLEKDEVVSKESFEERGTMLDASQIASKKAEINLLTPPIVKP
                     LSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVKENSILYQKEL
                     LSAVMMKDDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFAKLAEYSLGDTGL
                     LYTPNQFLYDQDSIINQVLPELQQVAYDSEAIRKTLGISPEVKQTELYMEDQFTKTKQ
                     DLANSLKKLLSADAGLAGDNPVTRGYLVDKIKNNKEALLLGLTYLERWYNFSYGQVNV
                     KNLVMYHLDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLASHHGTTDLFST
                     LENYRKVFLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSD
                     SWKYRNMVLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLNSFVEKSAHET
                     AERQRDHYDYWYRILDEKGREKLYRNILLYDAYKFGTDHTEGKATEVANFDNPNPAMK
                     HFFGPVGNKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHDSDQDIYLGGYG
                     RRSGLGPEFFAKGLLQAPDQPSDATITINSILKHKTSDSTEGQRLQVLDPTTRFNDAA
                     DLQNYVHNMFDVVYMLEYLEGQSIVKQLDAYQKMTALRKIENKYVKDPADGNDVYATN
                     VVKNLTEDEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAPIFSALSSEKG
                     TPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELV
                     LKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKRWPSYGTKTINNVDELQK
                     LMDEAVLQDATGTRWSNYNPEIDSAVHKLKRAIFKAYLAQTNDFRSSIFENKK"
BASE COUNT         6203 a         4212 c         4397 g         6791 t
ORIGIN      
        1 attcaaatcg tatatagtcg atttattaaa tctttagata aattgtaaaa agtggtttcc
       61 atagccactt tttgctataa tagaggcagt aaaaatgaag gagtcagcta tggaacactc
      121 gtcttggcat gctttgatta aggcgcaatt acctgagggt tatttcggga aaatcaatca
      181 gtttatggag caggtctatt ctcaggggat tatttatcca cccaaggaaa aggtttttca
      241 ggctctcttg acaacactgc ttgaagaagt taaggtggta attctagggc aagaccccta
      301 tcacggacca ggtcaagcgc agggcttgag tttttctgta cctgactcta tcccagctcc
      361 accatccttg caaaatatct tgaaagaatt gtcagatgat atcggagtta agaaatctca
      421 tgatttgaca gcttgggctg agcaaggagt cttgcttctt aatgcttgtt tgactgttcc
      481 tgctggacag gccaatggtc atgctggtca aatctgggag ccttttactg atgctgtgat
      541 tcaggtggtc aatcatctag atagaccagt cgtttttgta ctctggggag cttatgcacg
      601 taagaagaag gccttagtta ccaatcctca tcacttgatt atcgaatcag cccatccaag
      661 tcctttgtcg gtttatagag gattttgggg ttccaagccc ttttccaaag ccaatgcatt
      721 cttaaaagag acaggacaag agccaatcga ttggcttaga taaggagaaa atatgcctca
      781 gttagcgacg atttgctaca ttgataatgg gaaagaactg ctcatgctcc atcgtaataa
      841 gaaacccaat gatgtccatg aagggaaatg gattggtgtg ggtggtaagc tagagagagg
      901 agagacgccc caggaatgcg cggcgcgtga aatccttgaa gaaacagggc tcaaagccaa
      961 gccagttcta aaaggtgtca tcacttttcc tgaatttaca gcagatttag actggtacac
     1021 ctatgttttt aaggtgacgg agtttgaggg cgacttgatt gactgcaatg aggggacgct
     1081 agaatgggtt ccctatgacg aggttttgag caagccgact tgggaaggtg accacacctt
     1141 tgttgagtgg cttttagagg ataaaccctt cttttcagcc aagtttgttt atgatgggga
     1201 taaattgttg gatacccaag ttgatttcta tgaataaagg agaaagcaga tgctactaat
     1261 caaaaatggt catgtaatgg atcccaagtc tggtttggat caagtttgtg atgtcttagt
     1321 tcaagatggg aaaattatca aaattgcgcc tgagatcacg gaagaaggag cagaaacgat
     1381 tgatgctact ggtcttgtgg ttgctcctgg tttggtcgat attcatgtgc atttccgtga
     1441 acctggtcaa acacataaag aagacattca tactggtgcc ctagcagccg ctgcaggtgg
     1501 ttttactact gtcgtcatga tggctaatac cagtccaacc atttcagacg tggagacttt
     1561 gcaagcagtt ctccagtcag ctgccaaaga gaagattaat gtcaagacag ttgcgaccat
     1621 tactaaaaac tttaatggta aaaacttgac tgactttaag gcgctcttag aagctggtgc
     1681 ggttggtttc tctgatgacg gtattccgct tgagagcagt aagattgtca aggaagccat
     1741 ggaggaagcc aaaaaactca atacctttat cagccttcat gaggaagatc caggtttgaa
     1801 cggtgttctt ggctttaatg aaaatattgc tagagaacat ttccatatct gtggtgctac
     1861 tggggtggct gagtacgcta tgatggcgcg tgatgtcatg attgcctatg caactaaagc
     1921 ccatgttcac atccagcatt tgtctaagga agaaagtgtt aaagtagtgg agtttgctca
     1981 ggggttaggt gcagaagtca cagcagaagt agcaccacag catttctcta agacagaagc
     2041 acttctttta acacaaggta gcaatgctaa gatgaatcca ccgcttcgtt tggaatcaga
     2101 ccgtcgtgcc gttatcgaag gtctcaaatc aggtgtcatc acagttattg cgactgacca
     2161 cgcgcctcat catgtagatg aaaaaaatgt tgaagatatt accaaagcgc catctggtat
     2221 gactggctta gaaacatccc tgtctctcgg cttgacctat ttggtagaag ctggtgagtt
     2281 gagcttgatg gaattacttg aaaaaatgac atacaaccca gccaagcttt acaactttaa
     2341 agcaggttac ttggctgaga atggtccagc agatatcact atttttgatg ccaaggctga
     2401 ccgccttgtg gactcccatt ttgcttccaa agcagctaat tcaccattca tcggtgaaac
     2461 cttaaaaggg caggttaaat ataccatctg taagggacaa atcgtctatc aagcttgata
     2521 ggagttagaa tatgaattat tttcgaaaac gtagggagag acaagcgaaa tctaatagtg
     2581 gaatttactg tcccgcagct aatcgttcca aaattcaata tgaaactaaa gaaaaagctg
     2641 accatgcggt tcaatatgat aacggaggtt tagttagaag ctattattgt cgtacatgtg
     2701 cgtgttggca tactacttca aaatctaata aacctccgct aagtttgaaa aactatggtc
     2761 tgaaactctt tggtttagat aaatcagaat agaaagagaa gtatgtataa gacaaagtgt
     2821 ttacgagaga agttagtatt atttttaaaa attttcttcc caatcctgat ctaccaattt
     2881 gccaattatt ctgcctcttt tgttgatact gcaatgacag gtcaatacaa cactatggac
     2941 ttggctggtg tatctatggc aaccagtatc tggaatcctt tctttacatt tctaacaggg
     3001 attgtgtcag ccttggtgcc tatcattggt caccatcttg gtcgaggcaa aaaggaagaa
     3061 gttgcgtctg atttttacca atttatttat ttggccttgg gcctatctgt ggtcttgctg
     3121 gggatggtac ttttcttggc accaacaatc ttgaatcata ttgggttaga agcagcagta
     3181 gcggcagtag cggttcgcta tctttggttt ttatctatcg ggattatccc cttgttgctc
     3241 tttagcgtca ttcgttcctt gctggattcg ctgggcttga ccaaactgtc catgtacctc
     3301 atgcttttgt tactccctct caatagcgga tttaactatc tcttgattta cggtgccttt
     3361 ggtgttccag aactgggagg ggctggtgct ggtttaggaa catccttggc ctactgggtc
     3421 ttgcttggga tttctgttct ggttttattt aaacaggaga agctcaaagc cttacacctt
     3481 gagaaacgaa ttccacttaa tatggataac attaaggaag gagttcgttt aggtctgcct
     3541 attgggggaa ctgtcttcgc ggaagtggct atcttttcag tggttggctt gattatggct
     3601 aagttttcgt ccttgattat agctagtcac cagtcagcta tgaacttttc aagtcttatg
     3661 tacgcctttc ctatgagtat ctcatcggct atggctattg tcgtttccta tgaagtggga
     3721 gccaagcgat ttgatgatgc gaaaacctat attggtctag gaagatggac tgctctcatt
     3781 tttgcggcct tcaccctaac cttcctttac atttttaggg gaaatgtggc cagtctttat
     3841 ggtaacgacc caaaatttat cgatttgaca gcgcgttttt taacttatag tcttttcttc
     3901 cagttagcag atacctttgc ggcaccgctt cagggaattt tgcgggggta taaggataca
     3961 gttattcctt tttaccttgg tttgcttggt tattggggcg tagcaatccc tgtggctacg
     4021 ctatttgatt ccctaacaga ttttggagct tattcttact ggatcggctt gattattagt
     4081 ttgattgtga gtggggcgct ctaccgttgg cgtttaactg tgattatgaa gagatttgaa
     4141 tctttagcaa aatccaaacg ctaaaaagtt tgtgaaaaaa tatccttgac aagaaaatcc
     4201 cttgttttca cggggttttc ttttttattt tgtgaaattt cttttagaaa aactttgaca
     4261 gtatttgcca aaagcggtaa aatagtaagg taagaagaaa gttagaaagg caagaagatg
     4321 tcaactttag ataaaaatct tttgctagaa atgttccgta agatggaaga aatccgtcgc
     4381 atggacttaa aaattgcaca attagtaaag aaagggaaag tgccaggaat gacgcacttt
     4441 tctgttggtg aagaggcagc taacgtgggg gctatgttag ctctcaatcc agatgatctg
     4501 attacctcaa accaccgtgg acacgggcaa gctattgcta aagggattga cttcaacgga
     4561 atgatggctg aaatccttgg taaatacact ggaacctgta aagggaaagg tggatctatg
     4621 catatcgctg accttgatgc tgggaacctt ggtgccaatg gtatcgtagg tggtggtatg
     4681 gggatcgctg tcggtgcagc cctcagtcag caaatgcaaa ataccggtaa aatcgttgtc
     4741 tgcttctttg gagatggtgc gaccaatgaa ggtgttttcc acgaagcagt gaacatggct
     4801 tctatctgga acctgccagt cattttctat tgcattaaca acggttacgg tatctctgcg
     4861 gatatcaaga aaatgaccaa tatagaacat atccatcaac gtagcgccgc ttatggaatt
     4921 cctggaatgt tcatcgaaga cggtaacaat gtcatcgatg tctatgaagg atttcagaaa
     4981 gctatagacc atgttcgcag tggcaatggt ccagtcttga ttgaaagtgt aacttatcgc
     5041 tggctcggtc actcatcatc tgaccctggt aaatatcgta cgcgtgaaga agtggaattg
     5101 tggaaacaaa aagatccaat cgaaaacctc cgcaattacc ttattgaaaa taacattgca
     5161 agtgccgaag aattggaaga aatccaagcg caagtaaagg aagcagtaga agcttctgtt
     5221 aaatttgcag aggaaagccc attcccaccg cttgaatcag cctttgaaga tatttacgca
     5281 gactaaggag aaagagataa aatggaaaca aaaacaatgt ccttccgtga caccattatc
     5341 cttgctatgt ctgaggaaat gcgtcgcgat gaaaatgtgt tcttgatggg agaagacgtc
     5401 ggtgtcttcg gaggagactt cggtacttct gttggaatgc ttgaagaatt tggtccagaa
     5461 cgtgtccgtg actgtccgat ttctgaagct gccatctctg gagctgcagc aggagcagcc
     5521 atgacaggac ttcgtccaat cgtcgatatg accttcatgg acttctctgt tattgccatg
     5581 gacaatatcg tcaaccaagc tgctaaaaca cgttacatgt ttggtggtaa aggtcaggtt
     5641 ccaatgactg ttcgttgtgc agctggtaac ggagttggct ctgccgccca gcactcacaa
     5701 tctctagagt cttggtttac tcacattcca ggacttaagg ttgtggcacc tggaacacct
     5761 gcggacatga aaggcctgct taagtcttct atccgtgata acaacccagt tattatactt
     5821 gagtacaagt cagaatttaa ccaaaaaggg gaagtgccag ttgatccaga ctacacaatt
     5881 ccacttgggg ttggtgaaat caaacgccaa ggaacggatg taacagttgt cacttatgga
     5941 aaaatgcttc gccgtgtggt tcaagctgct gaagaattag ctgaagaagg aatttcagtt
     6001 gaaattgttg acccacgtac ccttgttccg cttgataagg atatcatcat aaactcagtg
     6061 aagaagactg gtaaggttgt tctggtcaac gatgcccaca aaacaagtgg ctatatcggt
     6121 gaaatttcag ctattatttc agaatcagaa gcatttgact atctagatgc accaatccgc
     6181 cgttgtgcag gagaagatgt gccgatgcct tatgcacaaa acctagaaaa tgcaatgatt
     6241 ccaacagttg aaagtatcaa agatgcaatc cgaaaaactt ataacaaaga atagagttac
     6301 ataagataag ttatgtaaat aaaacaaagc tgacgagaaa ctttgtatct tttaggtgca
     6361 gagctcttcg tccttaatat cttagattag agcacgggct aaaagcttgg aaaaaaagat
     6421 aaatctcctt ggcttcatcg aagccatcgt cgatttccta tttttcagtc gcttttgacg
     6481 ccctttgtat cataaataga attggagagg tcatggctga tgacaagcta agagcgactc
     6541 ctgcagctag aaagttagcg gatgatttag ggataaacct ctacgacgtt tctggctcag
     6601 gtgcaaacgg tcgtgtccac aaagaagacg tggaaactta taaagacaca aacgtggttc
     6661 gcatttcgcc acttgcaaaa cgaattgccc tcgaacataa cattgcttgg caggaaatcc
     6721 aaggaaccgg tcatcgtggt aaaatcatga agaaggatgt tttggccctg cttcctgaaa
     6781 atatcgaaaa cgatagcatc aaatctcctg ctcagattga aaaagtggaa gaagttcctg
     6841 ataacgtaac accatatggt gaaatcgagc gtattccaat gacaccaatg cgtaaggtta
     6901 ttgcccaacg catggttgaa tcttacttga ctgcgccaac cttcaccctc aactatgaag
     6961 ttgatatgac tgaaatgttg gctcttcgta agaaggttct tgagccaatc atggaagcaa
     7021 ctgggaagaa gactactgta acagaccttc tttcgcttgc agttgttaag actcttatga
     7081 aacacccata catcaacgct tcattgacag aagatggcaa gactattatc actcacaact
     7141 atgtcaatct tgccatggca gttgggatgg ataatggatt gatgacacct gttgtttaca
     7201 atgctgagaa gatgagtctt tcagaactgg ttgtagcctt taaggatgtt attggccgta
     7261 ccttggatgg taaattggct ccaagtgagt tacaaaattc aacattcaca atcagtaatt
     7321 tgggaatgtt tggtgttcag tcctttggtc cgattattaa ccaacccaac tcagctatcc
     7381 ttggtgtcag ttcgacaatc gagaagccag ttgtcgtcaa tggtgaaatt gtgattcgcc
     7441 caatcatgaa tttaggatta accattgacc accgtgtcgt agatggtatg gctggtgcta
     7501 agtttatgaa ggacttgaaa gagttgattg aaacgccaat ctcaatgttg atttaagagc
     7561 aagagtattc atttttaaga tatagataaa ggaaggaaga catggcctta gaagtaatta
     7621 tgccaaaagc cggcgtggat atgacagaag gacaaatcgt ccaatggaat aaaaaagtcg
     7681 gagaatttgt aaaagaagga gaaatccttt tggaaatcat gactgataaa gtaagcatgg
     7741 aattggaagc cgaagaagat gggtacttga ttgccattct caaaggagat ggtgaaactg
     7801 tccctgtaac ggaagttatc ggttaccttg gtgaagaaag ggaaaacatc ccaacagctg
     7861 gatcagcatc gccagaagct agccctgtcc ctgtagcaag tacctcaaac gatgatggta
     7921 agagcgatga tgcttttgat atcgttgtga ttggtggagg tcctgctggt tatgttgcag
     7981 ccattaaagc tgcccaactc ggcggtaagg ttgcccttgt tgagaaatct gaacttggtg
     8041 gaacctgctt aaaccgtgga tgtattccaa ccaagaccta ccttcataac gctgaaatta
     8101 ttgaaaatat cggtcatgct gcaaatcgtg gtatcgtgat tgaaaatcct aacttcactg
     8161 ttgatatgga aaaactttta gaaactaaat ctaaagttgt taatactctt gttggtggtg
     8221 ttgcaggact tcttcgtagc tacggagtta ctgttcataa aggaattggt acaatcacta
     8281 aagacaagaa cgtcttggta aatggttctg aattgcttga aaccaagaag atcattcttg
     8341 ctggtggttc aaaagtcagc aagatcaacg tccctggtat ggaatctcca cttgtcatga
     8401 ctagtgatga cattcttgaa atgaacgaag tgccagaaag ccttgttatc atcggtggtg
     8461 gagttgtcgg tatcgaactc ggtcaggcct tcatgacatt tggttcaaaa gtgactgtta
     8521 tcgaaatgat ggaccgtata gttccagcta tggatgcgga agtttctaag aaccttcgct
     8581 tgatccttga gcgtaaagga atgaccatct tgactggtac taaactgcaa gaaatcattg
     8641 aggaaaatgg tcaacttcgt atcaaggttg aaggaaaaga caatatcatc gcaagcaaag
     8701 ctcttctttc aattggtcgt atgccagacc ttgaaggtat tggagaggtt gagtttgaat
     8761 tggatcgtgg ttgtatcaag gtcaatgaat acatggaaac ttcagttcca ggcatttatg
     8821 caccaggtga catcaacggt actaagatgt tggctcacgc agctttccgc atgggtgaag
     8881 tttccgctga aaatgccctt aaaggaaatc atgcagttgc caaattgaat ttgactcctg
     8941 cagccatcta cactctccct gaagtagcag cagtaggttt gacagaagaa caagcccgtg
     9001 agaaatacga tgttgccatc ggtaagttta actttgctgc taacggtcgt gctattgcat
     9061 ctgacgcagc tcaaggtttc gtaaaagtta tcgctgataa gaaatacgga gaaatccttg
     9121 gtgtacacat tattggtcct gcagccgcag aattaataaa cgaagcatca agcatcatcg
     9181 aaatggaaat cactgttgag gaaatgctga agaccatcca cggacaccca acttactctg
     9241 aagtgatgta cgaagcgttt gcagatgttc taggaatggc catccattca cctaagaaaa
     9301 aataaaacga agatagatta gactggaagg ttatttccag tctctatcat ataaagtaaa
     9361 gggatatcat gaaatacatt atcaatcatt caaatgacac tgcttttaat attgccttgg
     9421 aagaatacgc ctttaaacac cttttggatg aggatcaaat cttcctactt tggattaaca
     9481 agccatctat cattgttggt cgtcaccaga acactatcga agaaatcaac cgtgattatg
     9541 ttcgcgaaaa tggtattgag gtagttcgcc gtattagtgg tggtggagct gtttaccacg
     9601 atttaaataa cctcaactac acgatcatct ccaaagaaga tgaaaataag gcatttgact
     9661 tcaagagctt ctcaactccg gttatcaata ccctggctca actcggggtt aaagctgagt
     9721 tcacaggtcg taatgacctt gagattgatg gtaagaagtt ctgtggcaat gcccaagcct
     9781 atatcaacgg ccgtatcatg caccacggtt gcttgctctt tgacgttgat ttgtcagtcc
     9841 tcgcaaatgc ccttaaggtt tcaaaagata aatttgaatc aaaaggtgtg aaatccgtcc
     9901 gtgcccgtgt aaccaatatt atcaatgaat taccaaaaaa aatcacagtc gaaaaattcc
     9961 gtgatttact cctggaatac atgaaaaaag agtacccaga gatgactgaa tacgtctttt
    10021 cagaagaaga attggccgaa atcaatcgca tcaaggatac taagtttgga acttgggact
    10081 ggaactatgg taaatcacct gaatttaacg tccgtcgtgg aaccaaattc actagtggta
    10141 aggttgaagt ctttgctaat gttactgaat caaaaatcca agacatcaag atttatggtg
    10201 acttctttgg tattgaagac gttgctgcag tagaagatgt ccttcgtggg gtgaaatacg
    10261 aacgcgaaga tgttcttaag gcgctaaaaa ctattgatat cacacgctac ttcgctggta
    10321 ttagccgtga agaaatcgct gaagcggtag ttggataaat caaaaagaag ttggccaact
    10381 tctttttttg atatttattt acataattta aaatacgtaa aatcataaac tatccagagc
    10441 attcttttgt tcatcactaa caatatgggt atagaggtca gtgacttgtg tgctagcatg
    10501 tcctagttgg tgactgacta aaacttgtga tttagtcgca tcatagagcc tagttgctag
    10561 tgtatggcgc agtttatggg gtgttacacg cactttaaaa tcctctgagt atttagcaac
    10621 cattttctca acgctagaag catcgatacg attaggaaca cctctgtaga gagttaaaaa
    10681 aagggctgta tctgtttttt ccgttttata gcgttgattc cgaatggcca gataattctc
    10741 taaataaggt ttagcaaaag cagcgacatt gactgagtca cgtttgccac cttttcgagt
    10801 aacatcaata accatcattt ttagattgag atctcttaga tctagattaa cagcttcaga
    10861 taagcgaaca ccagatgcca agagaagggc aataatggct aaatctcgtt ctttattttt
    10921 gttgaatgat gagagagctc gatttgaaag ctgttgtggg tgctcttgat cgatataagt
    10981 tagaaaacct tctgtttcat cacctagaaa gagtttttgc ttgatatttt cagctctggc
    11041 agcaagggtt tctttctttt tcttggttga aacttttttc attacattac gatagaaata
    11101 aggttccccc tgatcgtttt caacctcctc ggttagatac ttgtaaagac tagaaagtgc
    11161 tgataaggtt cgattgatag ttgtctgtga aacaccctgt tttgttgtat tagcattcag
    11221 caagggacgt tcacgtagat aaaggataaa ggattccatg tctttcttag acatattttc
    11281 caaaactgat aaaggaatat cggatatttt atcagcgttt gaaataccag acttcaaaac
    11341 ccagctgaaa aatcggtcat attccttaag gtattcgtac agggttgtaa aactgtaggg
    11401 tacagccagc ttagattggt agtattccag aacataccag ggcatgagtt gttttagttt
    11461 gtcgattcgt tccagtaaaa tctcacgttt catgtatttt ctccataagt aagtatacta
    11521 gtagtatagc atagacttgt atatttttca agaaaattat agtttttcag aaagatgtta
    11581 taggagtttt tcaaagtgat aaaaacactt agacctacaa acaaaacaga ataaggaaaa
    11641 taatgaaaat ctcacccact aaacttctgt taatactaca taactgaaga gctatataag
    11701 gagctatgag atacaaaaca cattgtataa tagattgaaa ctagaatagt acatctggac
    11761 ttctaaaaca ttgctagaaa ttgatttgat tgtcctgatt gttttatcct atttctattt
    11821 catttcacta tataattgct attgttttct ttttcatgat tttaatctta ctgtacagat
    11881 ttgatacagt aaactccttt ctagctttat actttatcat ttctaactta attatagtct
    11941 tatttttaat aaagttcaat tatttatatg taaaattcct catcagtaaa aaataaccga
    12001 tctcatttct gagaatcggt tttctaaata aatcaaaccg atcatttaca taacataaat
    12061 tatgtaaatg atcatactac aacaacaaat ctttgacttt tccaatttca ctttttggaa
    12121 taaccaggtg aatcatatca cccagataca ttctggttga gccgttaact gtttggctct
    12181 tgccattatg gacttgagtt gtgatgagga cgttgtgtgg taagttgagt tcatgaactt
    12241 gtttcccagc aattttatca gaaactggta tttcgataag tgtaacttct ccttcgctag
    12301 atacttcttc tggaagcatt ttttccagca tggcttcata gactggcgta cctttgagca
    12361 aatccatgat aatataagaa acaagagtga caagaccaag tggcataagg ttgcgaatat
    12421 ctcctaccat ctcagttacg aggatcatag cggttaaggg agcttttgat atggctccaa
    12481 aatagccact cattcctaga atgacaaata tagggaattg ctcttgactg acaagtccaa
    12541 gattgacaca gataacacca actaaggcac caagcaaaga accaagagct aaaatgggga
    12601 ggaaaattcc tcctggcagt ccacttccat agctaatcat actccaaata aagcggatta
    12661 aaaagtaagc taataaaact tggaaactaa aattttgttc agttaaagaa aggacaagct
    12721 gatttccgct accaatgatt tgaggtaaga agattccgac tggtatgata aggataaaag
    12781 ccaagatggg ataataagcc ctatccaaat ggattttttg accaatcaag tcataaactc
    12841 ttccaacgtt taatacagct ttctcataga gaaaacctga aaatccaagg aaaattccca
    12901 tgacgagata tatccaatac tgatctaggg tcatgggagg aatgttatct ggcatatcca
    12961 atactggtgt caaaccgaac atgagtagag acacaaagtt tgctacgatg ctggctgcta
    13021 gagttgagac ccagaaaaag cgcgaaaaat ggtgatagac ttcttctaca acaaagagaa
    13081 gtgctgcaat aggagcatta aaggctgcgg ctaaacctgc tgcagctcca ctggcaatca
    13141 aggaacgttc ctctactgga ctggatttga gccacttggc aattccttta ccaccaactg
    13201 ctccaagttg aatactgggt ccctctcgac ccagcatgag tccactggca atagcaagaa
    13261 tacctagcac atattttttc caaagaatgc cccaccagtt gagggacatg aggcctttca
    13321 gttcggcttc gacttgagga attcctgagc ctttaatatc tttttctgac cgtgttagtt
    13381 tggcactgag ccaacagatg agtatataaa acaaaaccag tacaaaaaga ttgcgcacta
    13441 agtacccttg atcttgataa actccttgta tcatgtggaa gcccttttca attaagaaac
    13501 gaaaggatcc gacgataatt ccaacgatga ggccgacaat gattcctcga ccaacttggg
    13561 atagtatagt gctggatgca aaggcgaatt ctttcttaga acggactatt tccgactgtt
    13621 cctccatggt atttcctttc aattaacttt cttttttacc taaaaccagt gatttaacgg
    13681 gttcaaagct ggttcggtga attggggtaa ctcctagttt tgtgaggcct tccagatgtt
    13741 tagctgtgcc atatcctgca ttagtagcga aatcatagcc agggaactgc tgatcgtatt
    13801 ctttcatcaa ttcatcacgt gttaccttgg ctactataga tgctgctgcg atagagaggg
    13861 agttggcatc tcctttgata atggaggttt gtgaaatggg caagtccagt ttcatggcat
    13921 caatcaaaag gtgctctggt tgagggctga gctgggagat tgcttcttgc atggctagtt
    13981 tggttgcttc atagatgttg acttggtcga tgacctgatt atctatgata ccaattccaa
    14041 tcgacaaggc ttggtcttga acggcttgga aaatctccag atgtttcttt ttaggaattt
    14101 tcttgctgtc gttgagacct ttaatcttac aatttttagg taaaatgacg gccgcagcga
    14161 ctacaggacc agcaagagga ccacgaccaa cctcatcaat acctacaatt aaggtcaatc
    14221 cttgcttata aagttctttt tcataagaaa gcatggattc caagcgcaaa ttttcatcta
    14281 attcagcttg aatggctctt ttacgcttgc tgatttcctt ttgaactcct gagcgattat
    14341 ccttttcaag ctctaaaaaa atagggcttt ctaactcctt gactgtcaca aggagttctt
    14401 tgatttcttt aatcgttgcc atcgaggtct tccaatgtat ctaaggtata gttaccgagt
    14461 ttgccatcac ggacttcctt cacgaagaga ctgtaaaaac ggtcatagtc atcacggaaa
    14521 ccgagggcgc gggtcatatc cataataatc acaggcgctt cttcttcaat tttcatttgt
    14581 ttgaagcgtt cagccagctt ttctggataa tgttctttga aataattgat accaaaaatg
    14641 gtaacctcat ccataggaag caactgatcc ttgatagctc cagtcaatgc caacttaagt
    14701 gcaacagttt catcctcaaa cttaggccag agaatccccg gtgtatccaa gatttccaga
    14761 tctttattgg ttttaagcca ttgttgacct tttgtgaccc ctggcttgtt tccaacaaca
    14821 gcaatctttt taccagccaa acggttcatc agagtggatt taccagcgtt tggaatcccg
    14881 ataatcatgg tacgcaaggt ttcaatctga atcccacgtt ctttctggcg agcaatctta
    14941 tcagccatga gcttcttggc cgcatctgtt acaactttta cagtcacttg ctctttggag
    15001 ttgatagcta gcgtctggat ttcttgtgat tcaaaatact gacgccattc cttggtcatt
    15061 gctggatcag ccaagtcggc cttgtttaaa atcaagagtt ttggtttatc accaacaatc
    15121 ttggtcaaca taggattttg actagataga ggcaagcgtg catctactaa aatcgtcaca
    15181 aaatcaacaa attttaaatt ttcctgcacc tgtcgacgcg ctttagacat gtgaccagga
    15241 aaccattgaa tagtagccat tgagtttttt cctttcgtag caaggattta gatcccctat
    15301 tttattttac tatagtttga acatagagag tcttcaaatg gatgatgtcc aaacagttct
    15361 tgttttatga catagaaatc tactttatat tatatcatgc cttctttatt ttgtccgatg
    15421 atagcctttt accctatctt ttaccctata tagaaaaaag ccatcaaatg atgacttttc
    15481 agagggagca aaaaactgtt cccgtcatat tatgaaccaa aagaactaaa ctaccaacag
    15541 ctaataggcc taaagctgta agcgcagaag ttgatgaacc tgttgcagga agagtttcct
    15601 gctgataaat aagagcataa cttacttcat tatcagtagg aattcctgct tgaatcttgg
    15661 tttgttcttc atcacctttt taaactttat ttcctaatag taaacactat tttttattct
    15721 caaaaattga acttctaaaa tcattggttt gagcaagata ggctttaaag attgctctct
    15781 tcaacttatg aactgcactg tctatttctg gattataatt actccaacgt gtacctgtag
    15841 catcctgcaa aacagcttca tccattagtt tctgcaattc atccacatta ttgatagtct
    15901 ttgtgccata gcttggccat cgttttgtcg gatctttaaa ggtcacctgc ttcaagtttc
    15961 caaactgatc cacccgttct tggtacatag ctgtcttaaa ttctgcccaa gttttatact
    16021 taccatcaaa tacctttttc aaaacaagct catcggtcac caagccccgt tctttaccat
    16081 aaagattgat agtttgccct tgttgtttag catcttcttc gtattgattt gagatatatg
    16141 gtaccatacc atctttaaag cctttagcag ctagtagttc ataggctata cgacgtccca
    16201 taaggtcgcc tggagttcct ttctcactgc tcaatgctga aaagattggt gcaaagagtt
    16261 ttatagtaaa gtagccattt ctctcataag tgccagcctt atactcacga gccgaaagaa
    16321 tgttattgtc aatcaaacta tcaaagctcg tcaatttttt agcttcatct tcagtcaaat
    16381 ttttcacaac attagtagca taaacatcat ttccatctgc aggatctttc acgtatttat
    16441 tctcgatttt tctcagggcc gtcattttct gataagcatc taactgtttc acgatagatt
    16501 gcccttcgag atattccaac atgtaaacga catcaaacat attgtggacg tagttctgaa
    16561 gatctgctgc gtcattaaat cttgtagttg gatcaagtac ttgcaatcgc tgaccttctg
    16621 tactatctga tgttttatgt ttcaagatag agttgatggt aatggttgca tcacttggtt
    16681 ggtctggtgc ttgtagtaag cctttagcaa agaactcagg tccaagtcca cttcttcttc
    16741 cataacctcc aagataaatg tcctgatctg agtcatgtgt catctcatgc gtataagtaa
    16801 tggcgccgtc cttgtccaac atacgataac ccatataata aacggcatcc cctgtagcat
    16861 aagcaccatg tccattatgt ccaaccttat ttccaacagg tccaaagaaa tgtttcattg
    16921 caggatttgg attatcaaaa tttgctactt ctgtagcctt tccttcagta tgatcagttc
    16981 caaatttata ggcatcataa agcaagatat ttcgataaag cttttcacgc cctttttcat
    17041 ctagaatacg ataccaataa tcatagtgat ctcgttgacg ctctgctgtt tcgtgagcac
    17101 tcttttcaac aaagctatta agatcaccat ttgcttgatg ttctttatta cgatagcgat
    17161 cataagcacc aaaacctaga ctagatatgg ttgaaatgac aaatacggat ctttctggca
    17221 aggtaagtag aggtagtacc atattacggt atttccagct gtcgctagtg attcgatcat
    17281 agacaccaat agaatactta gtaccaacta gtccttgctt cgttttcacc tcttcgatat
    17341 tggatttttc ttcgacaatg taagccttag tctgtgattt aaaccagtca ttattggttt
    17401 tgtctggtag aaagactttt cggtaatttt ccaacgtgct aaacaaatct gtcgttccat
    17461 gatggctggc aagactgata gcataagtat cgacattgtt tttagcaaga agattgttaa
    17521 agccagattt acctaactca atcagagtat ctaatggtga ggtatttcct ttaccaaaga
    17581 agtccagatg atacataact aggtttttga cattcacttg accatagcta aagttatacc
    17641 aacgttctaa ataagttaaa ccgagtagta aggcttcctt attgttcttg attttatcta
    17701 caagatagcc tctggtaact gggttgtcac cagcaagtcc agcatctgca gacaagagtt
    17761 ttttcaaact gtttgccaaa tcttgctttg ttttggtaaa ctggtcttcc atatagagct
    17821 cagtttgctt gacctctgga gaaattccga gtgtctttct gatagcttct gaatcgtagg
    17881 caacctgctg taattcaggt aaaacttgat tgatgataga gtcttggtca tacaagaatt
    17941 ggtttggcgt atagagaaga ccagtatctc ctagactata ttctgctaac ttagcaaaat
    18001 cagcctggta cctgagatca aacttttcag atgaatggtc cttgtagtga agcaagagtt
    18061 tgtttgcagt ctgtttgttg gaaataatat ctgtgattac ttggtcatcc ttcatcataa
    18121 ctgcagacaa gagttctttt tgatataaga tactgttctc cttaaccagg tttccgtatt
    18181 tcacgatggt cgccttgtta tagaaaggta acaatttttc aatgttctta taaaccaaag
    18241 cacggttggc ttgataatgg gctatcttag aaaaatcact gtctttctta ccgcttgttg
    18301 agaggggttt cactattggt ggagtgagaa gattgatttc tgcttttttg cttgcaattt
    18361 gagaagcatc tagcattgtt cctctttcct caaaggattc tttgctgacg acctcatcct
    18421 tctctaaagt gacattgaaa actttattcg ctttattact aaatgcatca gtaattttca
    18481 ttccattata atggtaacca ctaatggcat ttccattagt tacattgaca tcactaagca
    18541 cattagtcaa tcttccagca tgattttcac tatttgattc acgatcccat aagttacctg
    18601 ctataccagc aacttttcca aaacgttgac tattattaat atccccttca gaatagctat
    18661 tctgaatatg cgcatctttg tctacaagac cagcgatacc tccaacggtc tggtcagaac
    18721 tatttgtatt tgatgaaatg accactgtcg cttttgactt agtcagtgaa gctttgcttc
    18781 ctgtcaagtg accgaccagg ccaccgatat tataggaagc ggttgtttca taggtattga
    18841 caattcttcc cttgaaacta ctctctgtga tgcttgattg atctgcctta gccaacaaac
    18901 caccgatacc acgttcaccg gcaagtacac catccacatg aacttgctta atttttgtgt
    18961 tattctgagc ttcatttgcc agtgaaccga tatcatcttt ccctgaaata gagacatttt
    19021 tcagactcaa cttttctatt gtggcccctc tcaagctttc aaaaagaggc tttttcaagt
    19081 tgtaaatagc ataatgctta ccatcttttt caccaatcaa ctgaccagta aaggttccct
    19141 tgatatagga tttatcatca gtactaagct ccacttcgtt agcattcagg ctagctccta
    19201 aatgataggt tccagagaga ttttggttta tagctttgac cagattacta aaggaagtaa
    19261 agtttgttgt ttcttctgtt cccttcttag ctagatagaa ggtaaaatta tctttatatc
    19321 tgctttctat ctcctgctga agcttctcta cttttgctgt gattttataa aggattttat
    19381 cattttttct ttcctctgat attgatgcta ctggtaggta tacatctttg aatgaagaag
    19441 atttcacttt aacaaagtag ctatttggat tgcttggaac ttgttctaac gaaatgtgtt
    19501 gtttataagt accatttgac aaactgtata actctaggtc ggaaacattt cttaattcaa
    19561 gtgttttctc tggatcttct acctttttat cggggtctag ttcattttct tgtttaattt
    19621 cttcgtttcc atttgaattg gatgtgtttg atttggttga aacattctca gttgaatttc
    19681 cgtttgatgg ttctggttct gtttgtccat tctctgatgt tgtattacct gaattttctg
    19741 gttgatttga ttcttcaact ggtggttttg aatcactagg tttattggat acttccccag
    19801 tattttcgct agatgtatct ggtgatactt tctctgaatt cgttgttgat tcttctgcag
    19861 gttgaactgg attttctgct ccttgaattg aggttccttc tgtagtacct tcatttggat
    19921 ttactggtgt ttcttctgtt ggttttactg gaacttcttc agttttttct ggaccttgtt
    19981 ctttggtctt ctcaaccgga gtttcaggtt ttacttgctc aatattaccc ttatattctg
    20041 gaagcggtgc tacctgttta ggttcacctt tatcacttac cacagtatct gacgactctg
    20101 gttgaacctc agtctcacct ttgtcggtta cgactgcttc cgataacgct ggttgaactt
    20161 ctggtacgcc tttatcactt actacagctt cgggtaattc aggttggaca gcgggctcac
    20221 ctttgtcggt tacgactgct tccgataacg ctggttgaac ttctggtacg cctttatcac
    20281 ttactactgc ttcgggcaac tcaggctgaa ttgcgggttc aacaatagct ccagactgta
    20341 cgtccttatg ttctacacca gtctcaggtt gttcctttat aacttgagtt tttttagtac
    20401 ctttttcgac tattcttgga ctaggcgcag tcgttgaagt tgaaacaatt tctcgcgaaa
    20461 cttcttcctt gtttacagag aatattctga cgatttcaac tttcttacct aatttacctt
    20521 cttgttttac tcttacagtt ccttcagcta aatcaggatt ttcttgaatt tcttcttgaa
    20581 aatctatttt tgtctctata gtttcctcac gatataagag ttcaggtttg ttcaattgac
    20641 ctgataaaac ttcatcctgt ggatttaatg tatttacccc agtcttttct tttggagaaa
    20701 tcttctcctc tttcttcgtt tctagattct tatgttcggc taattgttct tgagaatctg
    20761 aagattgttt ctcttctttt cttggattga ttaatttagt agagaaaggt ttttcaacta
    20821 cttgaacttc tgtcggctta gttgaagaaa caggtgtttg ttcctgaata gcttgtactg
    20881 ttgatggatg gtctacaaaa tttggtgtaa cattataatc caccttttgt tgttttgtag
    20941 gagtggctgc tgatttttct tgattactta cttcaaaatc agaagtcgtt tttccctctt
    21001 tgatatatcc aatataagtg taacctgaaa tctctttagg aagaggtaat ttttctccag
    21061 aggtcaattc atagtccgta ttgtaattta gcaaaagatg attttctaaa gcatggactg
    21121 aaactaagac accatttcct attcccgcaa ccaatactaa atgtaatacc gttttattct
    21181 taaccttttt cttggaaaca gcaaaaatta aaattcccag agcagctaag ctagcaccag
    21241 caactagggc ttgcctctca ttcttgcttc cagtatttgg taattccgcc agttgatttt
    21301 gagaatttaa cttataaaca agataataag tttcatcatc attctccacg tatgtcggaa
    21361 tatcatagac aagctgcttc ttttcttctg atgatagctc tgaatctgcc acatatttat
    21421 agtgaactcc cgcagtttct tgagcatcca cagatgaact agctaataca gacataaaaa
    21481 ataaacttga aatcgttgca gatacaagtc ctactgataa ttttctaaat gaaaaacgct
    21541 cttgtttttc accaaaatac ttttccatta ttcctccttg aaataaaatt tatatatgtt
    21601 aca
//
LOCUS       DAVKMO010000032        20318 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVKMO010000032 DAVKMO010000000
VERSION     DAVKMO010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20318
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.032"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(78..227)
                     /locus_tag="VW361_001350"
                     /pseudo
     CDS             complement(78..227)
                     /locus_tag="VW361_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(381..2012)
                     /gene="rlmD"
                     /locus_tag="VW361_001351"
     CDS             complement(381..2012)
                     /gene="rlmD"
                     /locus_tag="VW361_001351"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9744384.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2086..3060)
                     /locus_tag="VW361_001352"
     CDS             complement(2086..3060)
                     /locus_tag="VW361_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU9744385.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3134..3748)
                     /gene="pmp23"
                     /locus_tag="VW361_001353"
     CDS             complement(3134..3748)
                     /gene="pmp23"
                     /locus_tag="VW361_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU9744386.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNRTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3748..4722)
                     /locus_tag="VW361_001354"
     CDS             complement(3748..4722)
                     /locus_tag="VW361_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU9744387.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLAYKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4730..5986)
                     /locus_tag="VW361_001355"
     CDS             complement(4730..5986)
                     /locus_tag="VW361_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU9744388.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYED"
     gene            complement(6048..6479)
                     /locus_tag="VW361_001356"
     CDS             complement(6048..6479)
                     /locus_tag="VW361_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744389.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6481..7080)
                     /locus_tag="VW361_001357"
     CDS             complement(6481..7080)
                     /locus_tag="VW361_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU9744390.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7067..7906)
                     /gene="prmC"
                     /locus_tag="VW361_001358"
     CDS             complement(7067..7906)
                     /gene="prmC"
                     /locus_tag="VW361_001358"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU9744391.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLANENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(7906..8985)
                     /gene="prfA"
                     /locus_tag="VW361_001359"
     CDS             complement(7906..8985)
                     /gene="prfA"
                     /locus_tag="VW361_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU9744392.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEELAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(8982..9572)
                     /locus_tag="VW361_001360"
     CDS             complement(8982..9572)
                     /locus_tag="VW361_001360"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU9744393.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPCCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            9695..9877
                     /locus_tag="VW361_001361"
     CDS             9695..9877
                     /locus_tag="VW361_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU9744394.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10014..11387
                     /gene="mnmE"
                     /locus_tag="VW361_001362"
     CDS             10014..11387
                     /gene="mnmE"
                     /locus_tag="VW361_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU9744395.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11434..12369)
                     /gene="dapA"
                     /locus_tag="VW361_001363"
     CDS             complement(11434..12369)
                     /gene="dapA"
                     /locus_tag="VW361_001363"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU9744396.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDVKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12425..13501)
                     /locus_tag="VW361_001364"
     CDS             complement(12425..13501)
                     /locus_tag="VW361_001364"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU9744397.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDSEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(13843..13915)
                     /locus_tag="VW361_001365"
     tRNA            complement(13843..13915)
                     /locus_tag="VW361_001365"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13880..13882),aa:Thr,seq:ggt)
     gene            complement(14015..14524)
                     /locus_tag="VW361_001366"
     CDS             complement(14015..14524)
                     /locus_tag="VW361_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU9744398.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(14522..14618)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            14647..15078
                     /locus_tag="VW361_001367"
     CDS             14647..15078
                     /locus_tag="VW361_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU9744399.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15160..15537
                     /gene="mscL"
                     /locus_tag="VW361_001368"
     CDS             15160..15537
                     /gene="mscL"
                     /locus_tag="VW361_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU9744400.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(15579..16673)
                     /gene="hemH"
                     /locus_tag="VW361_001369"
     CDS             complement(15579..16673)
                     /gene="hemH"
                     /locus_tag="VW361_001369"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU9744401.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGMRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENIKMPYLIKKMLEKAGKLPKE"
     gene            16827..18050
                     /gene="pepT"
                     /locus_tag="VW361_001370"
     CDS             16827..18050
                     /gene="pepT"
                     /locus_tag="VW361_001370"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU9744402.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18086..18418)
                     /locus_tag="VW361_001371"
     CDS             complement(18086..18418)
                     /locus_tag="VW361_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744403.1"
                     /translation="MDALLDQLSANSKDKTALLESTKAILVLNHQIQSKASASEETSP
                     ARNAEANGDNTSAENQPNATAESNIETASDENKPSNTRDSKPAESTSENKTTESSTTT
                     GNQEKPVE"
     gene            complement(18423..18716)
                     /locus_tag="VW361_001372"
     CDS             complement(18423..18716)
                     /locus_tag="VW361_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744404.1"
                     /translation="MSKANQLLERIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDPQTLVLYQKLYDILMSLHFYLESNNGSDADF"
     gene            18681..18902
                     /locus_tag="VW361_001373"
     CDS             18681..18902
                     /locus_tag="VW361_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744405.1"
                     /translation="MDSFQELICLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(19039..19248)
                     /locus_tag="VW361_001374"
                     /pseudo
     CDS             complement(19039..19248)
                     /locus_tag="VW361_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809565.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad protein"
     gene            complement(19369..19511)
                     /locus_tag="VW361_001375"
                     /pseudo
     CDS             complement(19369..19511)
                     /locus_tag="VW361_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262445.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(19545..19685)
                     /locus_tag="VW361_001376"
     CDS             complement(19545..19685)
                     /locus_tag="VW361_001376"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU9744406.1"
                     /translation="MLEITLKSPYQFAHILFQSTIVPHGGHYHFIPESDLSAGELAAA
                     KV"
     gene            complement(19729..20318)
                     /locus_tag="VW361_001377"
                     /pseudo
     CDS             complement(19729..20318)
                     /locus_tag="VW361_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         5861 a         4270 c         3840 g         6347 t
ORIGIN      
        1 ttaaactttg gtagaagtct tgaactcctt atatttacat aactatttgc ctctataact
       61 gttatgacac gaaaccaaca agcaagttca agcacctcca tatctttatt caaatgagga
      121 ctaagatatt cacaaacttt atcataaacc tctttatctt ttttcataaa aggggcatac
      181 aacttagcaa atttatccta aaattttttg ttgcctttat caatcatttc aacgctcctt
      241 taaatataaa aatgatccta tcaatcttta tattgagcct attttctaat tgataccttg
      301 caagaaagga ataatagctg ttcctatacc aagtaggaat gtaataaatg cagaaagtca
      361 tatactgtca ttcttttcta ttaaatcatt ttgaagtgtc tcaaagcatc catgatggct
      421 tcttcttttt caggtgtaca ctgtggaata atttgtttat cctttttaga cttgttgtaa
      481 tgttctcgta attctattcc acatttcttt tttatctgtg caatatataa tgtcgaaact
      541 tttaattcaa atttattcca aacatattct ttgatttgag catatgttgc tttgctctcc
      601 gcacttgtca aatccatctc atccagctca atttcaacac ttatgtgctt atcgacatcg
      661 agtttggaca aaagtgctac cgtctcgacg tgatgcgttt gaggaaatag atccaccggc
      721 tggactttct tcaattcata tcccaactct tggtatagtt taatatcacg cgccatggtt
      781 gcgacattgc aggagatata ggcgatgcga tcggctcctg tttgggcgct tgctttgata
      841 aagctttctg tcaagccctt gcgtggagga tcaaccaaga taacggttgg ttgaatccca
      901 tctttaagcc aattcttcat agcattttca gctgtgtcac agacatagtg ggcgtttgaa
      961 atattgttca gctgagcatt ttttttacta ttctcaaccg cttctggaat cagttcaaca
     1021 ccgtagactt ctttgacatg cttggcgact gataaaccaa tggttccaat accagaataa
     1081 gcatcaataa ccacatcatc tttttttaac tctgcaaagt caatggctgt ttgatagagt
     1141 ttctccgcca tttcagtatt gacttggtaa aaggctgggc cagcgatttg gaagtcattt
     1201 cccaacatct ggtccgtaat atagtcttga ccataaagag tgcgccactc cttaccaaaa
     1261 atcgcattgg tattctggtc gttgatattt tgcatgacag acacaatctc tgggaactgc
     1321 ttgataactt gttcaatcaa ttggtcaaca cgaaaaactt ttggacgagt tgtcaccaaa
     1381 acgaccatga tttgtcctga atagtgacca cgacgcacca caagattccg aatcaatcca
     1441 gactgttcct tttcgtcata aggttttaaa tcaaaacgac ggagcaggtc tcgaagagct
     1501 actacgactt ggtcaatgac aggatcctgg ataaagaaat cttcaagggg catgaggttg
     1561 tgcgaattct tacggaaaaa tcctgtttcc aagacaccat tcactcgacg aacgggcacc
     1621 tgcgccttat tgcgatactt gactggatgt tccataccaa gcgtttcagc aacttctaca
     1681 tctgcaattc cagcaatctt gtagagactg tccttgactt gcttggtttt aaacttgagc
     1741 tgttctggat aagaaaggtg tcctaaatcc gcgattcctg aacgcaggta agccaaatct
     1801 agatcttgat tacggtgtgg tgactggaca aggtattttt caacttttcc aaagccaatc
     1861 tttttattga ccttgaggac acgcatgaga attttttcac tcggtaaagc attctctaca
     1921 aaaaagacca aaccatctac cttggcaact cctgcccctt catgggtcaa atcaacaatt
     1981 tcaacttcta caatatcatt tttctttaac attcttttct ctttctattg gccgacaaaa
     2041 aagacggcaa cgttacggtt accatccatt ataccatgaa atttcttaag aaccaaaact
     2101 cttgaagaag ttgacaaggg cttgccagag ggagcttaag aagttaccac cgtcctctag
     2161 cgccttatcc gcatcaaagt taaggttgat atttttaaaa ctgtcgccag cttgtgatac
     2221 gatgctttgt ttaaggtcat ttaaggtttt agtgaaatct gcattgctga ggatatcact
     2281 ctttgagaga ttcaaggcaa aattgatgat gatattgatc tggtttcctg ttatgacctg
     2341 atcaagtttg taatttttta aggtatcttc aacaatcttg cggatatctt cttctgtcag
     2401 atttcccttg ctttctttag ctttggcgag tcctgacttg atatcagcta gggcaacgtt
     2461 taatttatta gcatcatagc ctgatttgtc cttgttttca gcattgatat ctgacaaagc
     2521 ctttagctct tcttgagcca aatctttatt ggcttgcggc accttggctc cattagcttc
     2581 tagcgaatag tagatcccag ccaaagcact ctcacctgta actggaatgg gtgctgctac
     2641 agtgattttg gcgtgttcca cacccaaagt tacggctgca tttcggtaca tatcctgagt
     2701 taccttagtg atgttttcag gtgtttcaat cttgacctca agtggcgatt tgtcacctag
     2761 cttttgaatc ttggctgatg aatacaactg taagctagag tcattggcca cattcatgat
     2821 tttagaataa acatcaggtg tcatggtctt gagttctttg gtatctgttg aggcattgta
     2881 gcccagtttt ttaagagttt gatttttttg gtcttcagat agggaagaac ctaggacata
     2941 ttcaggttgg acataggttt catcgataac tttttgaaca tctgttgctg catggacgct
     3001 attcatagct gttactgccc acaagatcgc agcgctagtc agaaagagtt tctttctcat
     3061 agggaatttc ctcctttact tctttagagt aatatatcta tcttaaagaa aacttataac
     3121 aaaaacacct ggtctagcca gatgttgaaa agagagtgaa acatttgatg atgtaaaggt
     3181 taagtcgtac ctgtctagaa taataatagt ttcctccatt tacatagagt tcagcaccgt
     3241 gaaaaatgga aatggggtga atataactat aagtctttcc agtcctatta ccaagcaagg
     3301 gggcaacagt ctcacgagag tactgtttgg ctagagccaa ggtattttcc ttgccatttt
     3361 gggcgataaa atcgatatag gcaggtccaa aattataggc ttgaacagct gtccagatat
     3421 ctacaccctt cttctgcgcc agatagagat tgcctgtcag agtttgaatg ccttgccgaa
     3481 tgctagaggc attatcattg atggtgttgg tggaaccact tgcagactca ctagactgca
     3541 taacatcgcc ttcttttcct tttgtttcag tataaatcat agcaagcaca agctcttcgt
     3601 ttgctggggt gtctttttca ctcaatattt ctcgcaccat gggttgatag gtcatgactt
     3661 gtttgacatc ttgatgaacg cggtaagctt tatagccagc aaaaaggaag actgctagta
     3721 caagcactct tcgaattcgt ttaaacatta tttactttgg atatcctcga tatttttgat
     3781 taagatagag taggttccat tttcgttttg gataaactca acagactcgg cgtcttgata
     3841 gacgttattg ggaacgatga gctcaattcc atttgataag gagagttttt ggttttcaaa
     3901 tttctttaat tggcgactgg catcaatttc atcaaattga acaggttctg gtacggcttc
     3961 tttgacttgg tcaataaagc tcaaacgagc cgtcagattg ttgtcaaaaa ggtcattagc
     4021 caatttctca ggtgacaatt cattgctttc ttctaggttg ttgaaaatag ctgatttgac
     4081 cttggattga aattgaaaat catctgtgtt aaaagattca gcaattctct gggctgtttt
     4141 ttccagttcc ttgatagatt ttttaggaga aatcttagga gcgacagcaa gaagattatc
     4201 tgaaaaatag ttcaaaaaag tcccgttgta cttgattcgt ttttcaatca ggtgatactt
     4261 gcgactctga agattgacca ccaaggcctc gtcagcaccc gttccaaatc caggcaggtt
     4321 attctgagtc agcttgattg gattatcaac ttctcctccg aggtgggtca aggtctcccg
     4381 cagggcaatt cgcaagaaag cgaaatgttc tacaccttct ttagaaaatt gaacaaaaat
     4441 caagtcattg gtcttgagat tttcagaaat gctaaactcc tctttccaga gattagccag
     4501 cgttactgat gtctccaaca aatcgtctgt aatatgattg aagaagggat tttcttcttc
     4561 gaaaatccca gtcttggctt catctgaata cacatgttca atttttttac gtaggtattc
     4621 ttcgattttt ggagtaatat tgagaaactt atatgctaag aacagctcgg tatcatccgg
     4681 actgaactgg tgaataatgg ctttcttaat ataaatgtcc ataaaagttt tagtcctcgt
     4741 ataatgggaa ggcatctgtc aattctttga ctgcacttct cacttcttct aatacagcct
     4801 cattttctga attcttaagg gttttaatga tgagttcagc cactttgcga ctttcttctt
     4861 caccaaatcc acgtgcagta atagctgctg ctccgatacg aatcccactt gtcttgaatg
     4921 gcgacaaggt ttcgtaaggg attgaatttt tatttagggt aatattgact tcatccagca
     4981 agttttgagc aacttttccg ttttctacaa ccttagtcac atcaacaagg aagagatggt
     5041 tttcagttcc acctgaaata atacggaaat cagggtcttg caagaagaca tctgccatag
     5101 ccttgctgtt cttaattaca ttggcagcat attccttgaa ggctggatcc aaaacttctt
     5161 tgaaggaaac tgccttagcc gccacaacat gctctaaagg accgccctga atacctggga
     5221 aaatagctga attgattttt ttagcaagtt cttcgtcatt ggtcaaaatc aaaccaccac
     5281 gaggtccacg aagggttttg tgggtcgttg ttgttgtgat atgagcgtat ggaactgggc
     5341 ttggatgaag gccagccgca accaaaccag cgatatgggc catgtccacc atgagcttcg
     5401 caccgacagc atctgcgatt tcacggaatt ttgaaaaatc gataatttga gaatatgctg
     5461 aagcaccagc tacaatcagt tttggtttta cttcttgggc ttgtttcaag atagcatcaa
     5521 agtctaagag ttccgtttca ggatcaacac tataagaaac aaagttgtag gtttgaccag
     5581 agaagctaac aggagcccca tgagtcaaat gaccacctga tgccaaatcc attcccataa
     5641 ccgtatcacc tggctcaatc aaggacatgt aagccgcaca gttagcttgg cttcctgaat
     5701 gtggttggac attggcaaat ttagcaccga aaatttcttt tgcgcgttca atagcaagag
     5761 tctctacaac gtctactaca tcagttccac cataataacg gcgtcctggg taaccctcgg
     5821 catatttatt tgtcaagata gacccttgag ctgccataac agccttggaa actacgtttt
     5881 ccgaagcaat taactcgata ttattttgtt ggcgttcttc ttctttggca atagcattcc
     5941 agagatcagc atcatatgct ttaaaatcat ctttgtcaaa aatcataggt cttctccttt
     6001 attgtgtgac tagtccatta gtttgatttt acaataagaa aatcaaacta aaagatgcga
     6061 ataaaccgtt tctgcatttt atcacaagta tagccaactt tttcataaaa tgcatgagca
     6121 cccagacgat gattggcaga atttaagcgg ataaacccat aaccacatct tttggcttct
     6181 tgttccaacc cttgtagtaa acttttaccg ataccttgac cttgcgcttg aggtgaaact
     6241 gctaaagcta agatattaaa tcctgctttg gaatagagtg attcgtaaac ttcagcgtgg
     6301 acatatccaa gtaagacatg attagctgca tcctcatagc caagtaggaa atgatgggaa
     6361 tcctgagaca gtctagctag ttggctagcc gtttcctctg gactaaaagt ataacccaaa
     6421 gcctcttggt tgatgtcaca tatcgctttc acatctgttt cttgcaaatc tcttagcatt
     6481 tcaagcctcc tcaaaagaaa tctctggcaa ccgagcaaga atatcttctc gtttaattgc
     6541 gccttggcgt aagattttca ccttgtctcc agacaaatcc acaatagttg aatcctgtcc
     6601 agttagaaaa gcatcgtctt ccagacccag aacctcttgg tcaaaatcct tcagaatttg
     6661 ttcaaaggtt acaccacttg cctgacctga gatattggca gacggcccaa tcaagggacc
     6721 tgtctctcga attaaatcca gtgtgatagg gtgactgggc atccgaaatc caatagttgc
     6781 aaggtcagaa tttacccaat agggaactcg gtcattggct tcgagaataa tggtcaaggg
     6841 acctggcaaa aaggtctcta caagtttttg tagataagct ggctgattct tagaaaagtg
     6901 caagatatcc tctaaagagg caacattgag attgagcgcc ttgtctctag gacgacgttt
     6961 gagctggtaa acatggtcaa ctgctttttc gtctaaggcc ttggcaaaaa gaccataaac
     7021 cgtctctgta ggcagaatga cagctccacc attttccaac tcttgtctaa tcctgtccat
     7081 catcaaccac gaccatccta tcttgaccaa attggtcctt gagtgttcga actttttttt
     7141 caggaagatg ttttctaaaa agttcgggaa cactttgacc ttgcttgtat ccaatttcaa
     7201 ggtaaatctt accaccatct ttgagatagt cttttgcatc ttccgcaatt ctacggtaaa
     7261 tagctaggcc atcctcgtct gcaaagagag ctagatgagg ctccgaatac aagacattca
     7321 agcctacctc tgactcatct tcacgagaga tatagggtgg attggaaaca attatatcat
     7381 atttttcaga aatttctgta aaacagtcag attttttaaa aaatatttga agattttgat
     7441 ttttagcatt ttcgttagct aaatctaaag cctcttgaga aacatctgct gctgtcactg
     7501 accaatctgg tctatttttt gctagagcga gagcaatagc tccactacct gttccaatat
     7561 ccagaactga aagattcgtc tcaagatttt cagttagaat aagctccact aactcctctg
     7621 tttctggacg aggaatcaaa acccgttcat ccacctttaa atgcattcca taaaaatctg
     7681 cctgtccaat gatgtactga gctggcttgt gagctgctag ttgctggtaa atatcttcta
     7741 caaattgttt ttcttcctct gttgtcacct cctgctggag ggcaaaaata aagtctgtaa
     7801 aagatagatt tttcagacta cgatagacaa aagagaggct ttccgcttcc tctccttgtc
     7861 ttatcaactc ttcttcaaaa tttgaaaata attgagctaa tttcattatt tgtttaattc
     7921 ttctagtttt tgtgtttggt cataaagcac caaggcatcc acaacttcgt ccaatttacc
     7981 agacaaaatc gtatctagtt tttggagggt caagccgata cggtggtctg tgacacggtt
     8041 ttgtgggaag ttataagttc ggatccgttc tgaacggtca ccagtaccga ttgtcgactt
     8101 acgctcagcg tcttgttcat cctgagcaat ctgagcaaag tggtcagcga cgcgtgcacg
     8161 gataatcttc atagccttct cgcggttctt ctgctgggta cgttcttcct gcatctcaac
     8221 cttgatattg gttggcaagt gaacgatacg aacggcagtc gcaaccttat tgacgttctg
     8281 tccaccagca ccagaggcgt gatagatgtc gacacgaagg tcttttggat caatgtcgta
     8341 ttcaacctct tcaacttctg gcataacaag aactgtcgct gtcgaagtat gaacacggcc
     8401 ttggctttct gtcacaggaa cacgttgcac acggtgggca cctgattcat acttaagctt
     8461 agagtataca gactgacctg aaaccatagc aaccacttct ttaaaaccac cgacaccatt
     8521 catagaggct tccatgactt caaagcgcca accttgggct tccgcatact tttggtacat
     8581 agttagcaaa tctccagcga aaagtgccgc ttcgtctcca ccagctgctc cacggatttc
     8641 aaggatgata ttcttgtcat cgtttggatc ctttggaagg agcaaaattt tcagtttttc
     8701 ttcatattct tctttttcag ccttggcatc tttgagttct tgcttggcca attcttccaa
     8761 gtccgcatct ccgcctgatt ccttaatcat ctcttcggca tcgacgatat tttgaaggac
     8821 ttgtttatac tcacggtagg ctattacggt gtcacgattt gaagcttctt cttttgaaag
     8881 ctccataaaa cgcttggtgt ctgaaacgac atcagggtca ctcagcaatt ctcctagttc
     8941 ttcataacgg tcttctacag cttgtagttg atcatagatg ttcatttttc ttcattctcc
     9001 ttattgattt caggggcaaa ataatgttta cggcaaaccg agatataggt ttcattacca
     9061 ccaatctgga tctgttctcc atcgtaaacg ggcagtccat cctgtgttcg caacaccatg
     9121 gtcgcctttt tcttgcaata ctgacagatg gtcttgattt cgtcaatctt gtccgctaaa
     9181 agcaagagat atttggaacc ttcgaacaat tcattgcgaa agtcattttt caagccaaaa
     9241 gccatgacgg gtatgtctaa ctcgtccaca acacgagcta ggtcgtaaac atggtggcgt
     9301 ttaagaaact gggcttcatc gaccaaaaca cagcaaggtt tttctggtag gtctcggata
     9361 tagccaaaga tatccgttgt ttcctcaatc gcaagggcag ggcgtttcat gccaattcga
     9421 ctcgacacat agccaacacc gtcacgcgta tccagagccg aggtcataat gacaacacct
     9481 tttccttgct cctcgtagtt ataggccact ttgagaatct caatcgtttt accagagttc
     9541 atggtcccat aacgatagta caactgtgcc atgtttcttg cttcacgtcc atttctaaat
     9601 ttttgctaca ttctagtata tcataatttt cttaagcttt aaacggcaaa atgtggtaaa
     9661 atggaagaaa tcaaaactag tggaggaagc tattatgcca tttgtacgca tcgatttatt
     9721 tgaaggacgc acgctcgagc aaaagaaagc tcttgctaag gaagtaacgg aagcagttgt
     9781 ccgcaacact ggagcccctc aatctgctgt ccatgtcatc atcaacgaca tgccagaagg
     9841 aacttacttc ccacaagggg aaatgcgtac taaataagct agcttaagca gaattgctta
     9901 ggctttttca atctccaagt agcattcatt gaagaaatat cctaaatttg ttacaatttg
     9961 aaaagaaact tggagaattt ccaagaaaag agctattaat taaaggaaac attatgatta
    10021 cacgtgaatt tgataccatc gctgctatct ctactccact aggtgaagga gctattggta
    10081 ttgtccgcct gagcggaaca gacagttttg ctattgcgca aaagattttt aaaggaaaag
    10141 acttgaacaa ggttgccagc cacactctca actacggtca cattattgat cctctgactg
    10201 gtaaagtcat ggacgaggtt atggttgggg ctatgaagtc tccaaagacc ttcactcgtg
    10261 aggatattat cgagattaac acccacggtg ggattgcggt gaccaatgaa attctccagc
    10321 tagctattcg tgaaggggct cggttggcag aacctggtga atttaccaaa cgtgcttttt
    10381 taaacggtcg cgtagacttg acacaggcag aggctgtgat ggatatcatc cgtgccaaga
    10441 ctgacaaggc catgaacatt gcggtcaaac aattagacgg ctccctttct gacctcatta
    10501 acaatacccg tcaagaaatc ctcaatacac ttgcccaagt tgaggtcaat atcgactatc
    10561 ctgaatatga tgatgttgag gaagctacta ctgccgttgt ccgtgagaag actatggagt
    10621 ttgagcaatt gctaaccaag ctccttagga cagcacgtcg tggtaaaatc cttcgtgaag
    10681 gaatttcaac ggctatcatt ggacgtccca acgttgggaa atcaagcctt ctcaacaacc
    10741 tcttgcgtga ggacaaggct atcgtaaccg atatcgctgg gacaacacga gatgtcatcg
    10801 aagagtacgt caacatcaat ggtgttcctc taaaattgat tgacacagct ggtattcgtg
    10861 aaacggatga tatcgttgaa caaatcggtg ttgagcgttc gaaaaaagcc ctcaaggaag
    10921 ccgacttggt tctactagtg ctaaatgcca gtgaaccact gactgcgcaa gacagacaac
    10981 ttcttgaaat tagccaagat accaatcgca ttattctact taataaaacc gacctgccag
    11041 aaacgattga aacttcgaaa ctacctgaag acgttatccg tatttcagtc cttaaaaacc
    11101 aaaacatcga caagattgaa gagcgaatca acaacctctt ctttgaaaat gctggcttgg
    11161 tcgagcaaga tgctacttac ttgtcaaacg cccgtcacat ttccctgatt gaaaaagcag
    11221 ttgaaagcct acaagccgtt aatcaaggtc ttgagctggg gatgccagtt gatttgcttc
    11281 aagttgactt gactcgtact tgggaaatcc tcggagaaat cactggggat gctgctccag
    11341 atgaactcat cacccaactc tttagccaat tctgtttagg aaaataagaa aaatccatga
    11401 tccttcattc ggtcatggat tttattgtct ttattagtaa tctggtctta agacccctgt
    11461 tacagttgcc ttagttgctt cgtagtcgcc atctacgaca accttgataa tgcgtttgac
    11521 atcttcttct ggtgctggaa caagaggtag acgagtgggt ccagcttcaa atcccatata
    11581 gttaagaatt gccttaactg gagcaggact tggataagag aagagagcat taaccttagg
    11641 aatgaattta cgctgaattg ctgcggcttt cttcatatcg ctttctgcaa tggcagtaaa
    11701 catctcgtgc atttcatccc catttgtatg agaggcaaca gaaataaccc catccgcccc
    11761 aaggttcatg gcatggaaag catctccatc ctcacctgta taaatcaaga actcttcagg
    11821 cttgtgctca atcaagtaag ccatattagc caagctagta cattctttga caccgataat
    11881 atttggatgg tcagccaagc gaagcatggt ttctggagtc aattcgacaa ctacacgccc
    11941 tggaatgtta tagataataa ttggtaggtc agaagcatct gcaatagcct taaagtgctg
    12001 atacatccct tcttgagaag gtttgttgta gtaaggaaca atagcaagcc cagctgcgaa
    12061 accaccaaat tccgctactt ctttgacaaa ctcaatagag tcacgcgtat cattagtacc
    12121 tacacccgca atcaaaggaa cgcgtccatt gacaaccttt tgtacagccg caaacaactc
    12181 caactcctca tcgtgggtca aagttggact ctcagcagtc gttcctgcga gaagaattcc
    12241 atccgtatga tgggccaata aatgctcaat caaggctgga atagcatcaa agttaatgga
    12301 accatcctca tggaaggggg taataaaggc tgtaatgatt ttacattctt ttaaatcttg
    12361 ataagacacg aaaacacctc tctatttcaa agaaggagtt catctgaact cctaaacgat
    12421 atgactattt taattcaaat ttcaattcgg ctgttggacg aaccaatcca cgttcatgaa
    12481 gagtttcagc aatctgaact gagttccaag cagcaccttt gagaaggtta tctgaaacaa
    12541 cccacatgtg aattcctttt tctgaatcca agtctttacg gatacgacca acaaaggtat
    12601 cacgcgaacc aactgcattg atagcttgag gatagatttg atgagctaca tcatcttcaa
    12661 gaacagcacc tgggaaggct gcgatagctg cttttacttc ttcgattgga gccacttctt
    12721 ttgtttcgat ataaacagac tcagagtgag ctgacaagac tggaatacgc acacatgttg
    12781 cagatactgc aatgctatca tcttccataa ttttcttagt ttccttggtc atcttcatct
    12841 cttcgtacgt gtaatcatta tcagtgaaaa catcaatttg tggaagagcg ttaaaggcga
    12901 taggataatg tttcttgtca ccacctgaag gcaagatttc cgcatgcaaa tcacgtggtt
    12961 tcacaccatc attcaagact tcacgaagtt cacgttgtgt ctcaagaatt gctcccatac
    13021 cagcacctga aacggcttga taagttgaaa caatgatacg gtccaagccc catttttggc
    13081 gaaccggctc aagagccacc atcatttgga ttgttgaaca attagggcag gcaatgattc
    13141 cgttgtgagc atcaagtgca tgagcattga cctctggaac aaccaaagga acatctggat
    13201 tttgacggaa ataagatgta ttatctacta ctaccacgcc agcttttact gcgtatggtg
    13261 catacttagc tgatgtagaa ctacctgctg aaaagagagc aatatcaact ccttcaaaag
    13321 ctgtttcagt cgtttcttca attgtaatat cttgatcttt aaatttcaat gacttacctg
    13381 ctgaacgtgc agaagcaagg taacgaattt tatcgattgg aagtgttgat tcttccaaca
    13441 tttttatcat ctgagcaccg acagcacctg tcgcgccgac tacagcaact gtatatccca
    13501 taaataacct ctttcggaat tttctaaaaa tttctataat agaagtatta tactactttt
    13561 tccatgaatt gcaaagcttt ttcatcattt tttggaaaat aaaaatccca gtcgctagac
    13621 tagggactaa gaggcatctt catgtgatga gcaggttcac acaactcatc aaggtccgct
    13681 cctgcgttat gacctcctta tgctcaatag tagtccgaag actacctatc gactcatcgc
    13741 atattctata ttactagaga tacttgattt tgtcaataag aaattttttc gatcgagtat
    13801 aacaaaaaac tctcatattc aagagtttcc ctatacatat catgctaatt gccgggattg
    13861 aaccggcgac ctcatcctta ccatggatgc gctctgccaa ctgagctaaa tcagcttact
    13921 taagaagtat actatattca gaaaaacttg tcaagtttcc ttagaaattt tccataggaa
    13981 aaagccaggt aagaactacc tagcttatct tcttctattt acttaaatca attcgacgac
    14041 caattttacc aataataatc gccccaataa tcaatgaagc aaattcaccg attcctgttg
    14101 taaaccaagt aaggaagaat ggtaattctg ctacaatatt taactctgca gcgatagtaa
    14161 acatggaaat tgaaaagagg attgaaaaga agaaatgatc ttttcgaatc aatccgttaa
    14221 agaggtaatc cttgctatat tttgcaaaaa gccaaacacc taaactgagg aatactaagg
    14281 ttgaaccacc accaacaaag acatctagca gtccgaagct aaagaaatta gcaatcatac
    14341 aaccgatggt aactccgatg atgtacttag gattgtaaaa agccataaag ttcatcattt
    14401 ctgaaatacg aaactgataa gcaccatagc tgatggcatt taggggcggt gtgacagtca
    14461 aaacgacgta gatagcagcg acgattgcaa tatctgcaac atcacgaata gttaattttt
    14521 tcatcttttc tcctttggcg gttatccgcg tgtaatatgc ttggtgaaag aagctaagca
    14581 ccaagggttg attcattcaa ccttactagt atagcacaat agcctgcttt atgctatact
    14641 taaagcatga aaaaacctat tcaaaaattt tttaacaatg aaatcttagc ctatctcttt
    14701 tttggccttg cgacaactct agtttcgatt ctctcacgac tagtcattta tcaactaagt
    14761 catcaggaac tccttgctac ggccttggca aatattatcg gtatcttatt tgcctttatc
    14821 acaaatgata cgattgtatt taagcaaaaa aagaaaaata gacttatccg tttagtgaaa
    14881 ttttctcttg ctcgcctttc tacttttctg ttagacttgt ttttaacttt tctctttgta
    14941 acccaatttc ctcacatcat agggcaattc gtaactgaaa acattgataa gataaatgct
    15001 attgaaacaa taattgcaca aatattcatt attatcatca attatatatt gagcaaggtc
    15061 tatattttta gaaaataatg ctccatttat gagcctttta attgccttct ataatgattt
    15121 aggatacaat gaaacacgaa acattgaaag gaaaacagta tgttaaaaaa tctaaaatcg
    15181 ttcttgcttc gaggaaatgt tattgacctt gctgtcggtg ttgtcattgc ctctgctttt
    15241 ggtgctatcg ttacttcact tgtaaacgac attatcactc ctcttatttt aaatcccgct
    15301 ttgaaagctg ctaaagtcga acgtatcgct caactttctt ggcatggagt cggctatggt
    15361 aactttttaa gtgctattat caattttatc tttgtgggta ccgccctctt ctttattatc
    15421 aagggcattg aaaaagcaca gaaactgact ggcataaaga aagaaaaaac tgccgaaaaa
    15481 aaaccaaccg aattggaagt ccttcaagaa ataaaagctc tccttgagaa aaaataatcg
    15541 attaaaagga tctagcgcaa agctaaatcc ttttttcttt actctttggg taacttgcct
    15601 gctttttcaa gcattttttt gataagataa ggcatcttaa tattctcccg cccttttttc
    15661 tcaatcagtt ttttcacaaa ttctggcatt tgtaaatctt cagattcagc taaaatgttt
    15721 ttcgtctcgt ctgaaggaac taactcatca aaggtctctt cttctgggag aaattcctta
    15781 aactcttgat tttcattgac tctaactgta ttgaccaaag catcaatcaa acgagaatct
    15841 gtatttggca ttggtggacg atggtagttt accccaaatt cctgacataa atcataacat
    15901 tccacatcat tgtcaaacaa gacctcaata tgctcactga tgaaactaat aggtacaaaa
    15961 atataatggt ctggatgttc tgtctgttct ctgagatact ccaaaacatc tggtttaatc
    16021 catggaatac caatatcact ctcactctgc caagtgttgg tatattgttc tgaactcaag
    16081 cccagttttt cagcgactag cttgctattt tcgaaaattt ggtctatata aggatctcca
    16141 aagtccaagg caaaaatagg cacactatgg gctgaaaaga tgactttaaa gctgtcttgc
    16201 tttacttctt cttttaaaat cttagcaatt tcatctgccc aatagtttaa gagcgcttct
    16261 tcctgatacc agtccttaat gaccaaaaat tgaatttgtt tgctttctaa aaatttttca
    16321 tagcccatga cagagtagaa agaatagtgg ggctccaaaa tcaagcaaat acactgttca
    16381 attccgtctg cttccatttg accgatcaca tctggaataa agggactgga aaacttatta
    16441 gcaaagtaga cactgtattc attccccagc ctagcttcta ccaaggcaac ctcttgacgg
    16501 gtaatttttt gcagaggcgt gcctccaatt cgtacataat tatcatagag agtctgaatc
    16561 tcgtggtctt ggggtctcat cccacgacga atatttgtga aaaaatcagc tacaccttca
    16621 aaggtaatct cttctggtga accgaaggtc atcattaaaa ttgctttttt catgactgct
    16681 tccttgtgat gtttttatca agtttatttt atcattaatt catcgataag taaacgctag
    16741 catagggaca ttctcaatct tctgtctttt gtttttctct tctttctatg atacaatgga
    16801 aaaaataaat tcaaaaggag ttttttatga cttatccaaa tctcttggac cgcttcttaa
    16861 cctacgttaa ggtcaacacg cgctctgatg aacactctac tactactcca agtacacaga
    16921 gtcaggttga cttcgcaaca aatgtcctaa ttcctgaaat gaaacgtgtt ggactgcaaa
    16981 atgtttacta tctaccgaat ggttttgcta ttggaacctt gccagccaac gatccgtctt
    17041 taacacgtaa gattggtttt atatcgcaca tggatactgc tgattttaat gctgaaggag
    17101 tcaatccaca ggtaattgaa aactacgatg gtggtgtgat tgaactaggg aattctggtt
    17161 tcaaactcga tccagccgac ttcaagagtc ttgaaaaata tccaggacaa acgctcatca
    17221 caacagatgg aacaaccttg ctaggtgctg atgacaagtc aggaattgct gaaattatga
    17281 cagccattga atatctaact gctcatcctg aaattaagca ctgtgagatt cgtgttggtt
    17341 ttggtccaga tgaagaaatc ggtgttggtg ccaataaatt tgatgcagaa gattttgatg
    17401 tggattttgc ctacactgtt gatggtggtc cactaggtga acttcagtac gagactttct
    17461 cagccgctgg tgctgaattg catttccaag gccgtaatgt ccaccctggt actgccaaag
    17521 ggcagatggt caatgccctt cagctagcaa ttgattttca taatcaactt ccagaaaatg
    17581 accgacctga gttaactgaa ggttaccaag gtttttacca tctaatggat gtgacaggta
    17641 gtgttgagga ggcgcgtgca agctacatca ttcgtgattt tgaaaaagat gcctttgaag
    17701 cgcgtaaagc atccatgcaa tctatcgctg ataagatgaa tgaagaactt gggagcaacc
    17761 gtgtcactct caacttgaca gaccagtact acaatatgaa agaagtcatt gaaaaagata
    17821 tgactccaat taccattgct aaagccgtta tggaagatct aggtatcacg cctattatcg
    17881 aaccaatccg gggtggaaca gacggctcta agatttcctt tatgggaatc ccaactccga
    17941 atatctttgc aggtggcgaa aatatgcacg gacgttttga atacgttagc cttcagacta
    18001 tggaacgtgc agttgatacc atcattggca tcgtagctta taaaggctaa aaagacgagg
    18061 tagctcagct acttcgcctt tctttttatt ctactggttt ttcttgattt ccagtagttg
    18121 tagaagattc tgttgtttta ttttctgaag ttgattcagc aggtttagaa tctcttgtat
    18181 tgcttggttt gttttcgtcg ctagcagttt caatgttaga ttctgcagtt gcgtttggtt
    18241 ggttctcagc actggtgtta tcaccatttg cttcagcatt tcttgctgga cttgtttctt
    18301 cacttgcgct agcttttgac tggatttgat gattcaaaac tagaatagct tttgtcgatt
    18361 caagtaaagc tgttttgtct ttactattag cagaaagttg atctaataat gcatccacct
    18421 tatcaaaagt ccgcatcaga tccattatta ctttctaaat aaaagtgaag cgacatgaga
    18481 atatcgtaga gtttttgata gagtacaagt gtctgaggat cttgctcagc attttccttt
    18541 tcttgttgaa gggcgctagc gatacgagtc aagacatctt ttacctgact gtttacttca
    18601 tccaagtctg catcagcctt gtttgtggca gcttttagat tttctacttc ttctgccaaa
    18661 gattgtctga ttccttcttc atggattcgt tccaagagtt gatttgcctt gctcaaaaga
    18721 ctttctactt cttccttgct atctgtcgca gattattggt tgctatctac catgtactcc
    18781 taaaacagga gagttataat ccaagattac aaggccttac agaaataaga aatccagata
    18841 agacaatgtt cgtccaagac gctattcgct tcgcacagca gcacggattc aatatgcttt
    18901 aattttaaag tttaggtgtc aagacctctt tttagtgtgc ccaaaattta gagaagtaat
    18961 caatcaacta acttttattt ttttcaaact ttcagtaaac tgacctaaag ctaactcaat
    19021 ctgtctttgt tcgataggct tgtctttgta gatgcttctg ctatcagcta gaagttgatc
    19081 tacttttgcc aagactgcct tctcatcaaa agttccaggt tgatagttgg attgcaggga
    19141 tggaatcttg tttttcaaag ccgcttcata tcccttagtt tgaaccttga tgtagtgatt
    19201 gtggtcgcca cgaggaatca caaaaccttc tgaatcttca cttataattc gattggcatc
    19261 aaaaccatga ccatcttctt cctcatggtg gacatgtagt gacggattac ttaatacaga
    19321 actagaagaa cttcctacct tttccgtgtt agagtgtgat gggggattgt taagagatga
    19381 cttaggaata tagtgatagt gaccccatgt cttactatat aagcatcacc tgtatctctg
    19441 acaatatcat tagggttaaa gacataacca tcatctgctg cagaaacacc attattcggt
    19501 gtcaccgaca aagattgact gagagctgta gtattctctg ataattatac ttttgcagct
    19561 gctaattcac ctgccgacaa gtcactctca ggaatgaaat gatagtgacc accatgtggt
    19621 actatagtag attgaaatag aatatgagca aattgataag gggattttaa agtaatttct
    19681 aacaatgatt tagaaactat gatgtgctat tctaaattca actcactata tataaccatc
    19741 atcggtagta taacgtccct gtaattttgc tacagatact tctgcactag ctcctttatc
    19801 gtctttacca tgttcttgtt tttggcgatt gatttcatct tttattcgta cattttctgc
    19861 atgagcttga tctttaaggt aaacataata ctttccatct accttaataa tatatcctcc
    19921 cttaacctaa ctgacgatat cttgatcttt cggctgatag ttgggggctt tcattaatag
    19981 ctcttcacta aagagcgcat ccaaaggaac tttaccatta tagcagtgat aatgatcgcc
    20041 atgagaagtt acataacctt gatctgtaat cttaataaca atttgttttg cttgaattcc
    20101 ttctttttga ctaacctagt ctggagtcaa attttcagtc ttcttagtgt ctttattact
    20161 ctggagtcaa attttcagtc ttcttagtgt ctttattact gtttacatat gaaacacgat
    20221 ttttatctgt attggcctgt tagctatgtt ggttcagagc ataaacacac agacttaagg
    20281 aaaggataac aacagatcca gctgctatat atttcttt
//
LOCUS       DAVKMO010000033        20278 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVKMO010000033 DAVKMO010000000
VERSION     DAVKMO010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.033"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..461)
                     /locus_tag="VW361_001378"
     CDS             complement(<1..461)
                     /locus_tag="VW361_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744407.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIK"
     gene            complement(427..990)
                     /locus_tag="VW361_001379"
     CDS             complement(427..990)
                     /locus_tag="VW361_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744408.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLVLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            complement(1000..2988)
                     /gene="uvrB"
                     /locus_tag="VW361_001380"
     CDS             complement(1000..2988)
                     /gene="uvrB"
                     /locus_tag="VW361_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU9744409.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(3065..4018)
                     /locus_tag="VW361_001381"
     CDS             complement(3065..4018)
                     /locus_tag="VW361_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9744410.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            4188..6353
                     /locus_tag="VW361_001382"
     CDS             4188..6353
                     /locus_tag="VW361_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9744411.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            6353..7093
                     /locus_tag="VW361_001383"
     CDS             6353..7093
                     /locus_tag="VW361_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9744412.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            7242..8729
                     /locus_tag="VW361_001384"
     CDS             7242..8729
                     /locus_tag="VW361_001384"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU9744413.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDLEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPPHDYKAGSMGPQASFDLLEKFDAKWTWQPDIAYRQDGRFE"
     gene            complement(8773..10062)
                     /gene="ftsY"
                     /locus_tag="VW361_001385"
     CDS             complement(8773..10062)
                     /gene="ftsY"
                     /locus_tag="VW361_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU9744414.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTIEENNSEVLEPERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKRTGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(10066..10884)
                     /locus_tag="VW361_001386"
     CDS             complement(10066..10884)
                     /locus_tag="VW361_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9744415.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYADVARLYEKTE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGINQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            complement(10884..11678)
                     /locus_tag="VW361_001387"
     CDS             complement(10884..11678)
                     /locus_tag="VW361_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9744416.1"
                     /translation="MTIKLVATDMDGTFLDENGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYI
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            complement(11675..15214)
                     /gene="smc"
                     /locus_tag="VW361_001388"
     CDS             complement(11675..15214)
                     /gene="smc"
                     /locus_tag="VW361_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU9744417.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQTQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVYYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHAREAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLGSEEVALKTLQDEMARLTESLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDRYEEVHNRLDFLNSQRDDILSAKNLLLETITKMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            complement(15205..15903)
                     /locus_tag="VW361_001389"
     CDS             complement(15205..15903)
                     /locus_tag="VW361_001389"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU9744418.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            complement(16086..16157)
                     /locus_tag="VW361_001390"
     tRNA            complement(16086..16157)
                     /locus_tag="VW361_001390"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16122..16124),aa:Arg,seq:ccg)
     gene            complement(16221..17207)
                     /locus_tag="VW361_001391"
     CDS             complement(16221..17207)
                     /locus_tag="VW361_001391"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU9744419.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVSQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            complement(17382..18698)
                     /locus_tag="VW361_001392"
     CDS             complement(17382..18698)
                     /locus_tag="VW361_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU9744420.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLYINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            complement(18685..19944)
                     /locus_tag="VW361_001393"
                     /pseudo
     CDS             complement(18685..19944)
                     /locus_tag="VW361_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
BASE COUNT         5869 a         4545 c         3634 g         6230 t
ORIGIN      
        1 tcctttatag gctttccaag ttcaagtatt ttttcttgtc catcaaaagt aaaacccatt
       61 ttttgataga aagcaatggc gcgcttgtta tctttcaata cccataagaa aatttcagaa
      121 aaatgattaa gagcagtcaa agctgctttc attaactttt gtgcgatacc ttttccataa
      181 tagtctttta aaacatataa agcaataatt tcaccagctt gaatagtctc atcacgaaaa
      241 ttgccataac tgataaaacc aaccaccttc acgccatcca tcgcaatcaa tgtattttct
      301 ggatactttt gactaaagaa tcgacatctt tctaatgtca ttgtatcctg aaattccgca
      361 ggcaaaaggt catcataaga ctctctccac gtttgccagt gaacgaggga tttgccttct
      421 atctcttcag gagtttccat tgatttgata ataaccgtca tttattttct cccagtcttc
      481 tctcaaaata ccatatttaa tactatcaaa atatttacct tgataataac gaacttttgg
      541 aatatgagct tcttttttca ttcttaattt ttcagcaagt ttcatcatac caagatttcc
      601 tgaccaagtt gtcaaaacca gatgctccaa ctccaagtaa tcctgaaacg tcctatctat
      661 ccactgcaac atagcaactt tcccaatacc agtgttccag aattttttat cataaatacc
      721 aattcccaat tccatccatc ttgtttcttt acatacccaa taacgcgaaa cagtcccaac
      781 tagtttatca tcaacaaaaa taccaaggcg atttgagttg cttaaaatgg attctgattt
      841 ttgtagttcg aattctttaa aatttgaaaa atactgataa tcatcataat agggagcatc
      901 atactgtttc caaactggat taagttgtga ataagccatt tcccataaag acatcaaatc
      961 ttctctcttt aactttctta aataaatcat actattcccc taatccaagg ccttgacttc
     1021 caacatcata tcacggatct gagccgccag ttcaaagtca agcacttcga cggcttcttg
     1081 catttgtttt tctagtttct tgacgagttc tttgcgctct tgtttgttga ggctattgat
     1141 gtcgacttcc ttgtcctctt ccttagcaac tgccttggtc acggcaatca ggtcacggat
     1201 ttctttcttg attgtctgtg gtacgatacc atgctcttca ttataggcca tctgaatttt
     1261 ccgacggcgg gcagtttcat cgatagcacg ttgcatagac tgggtaaccg tgtctgcata
     1321 catgatgaca tggccttcac tgttacgagc agcacgtcca atagtctgga tgagtccacg
     1381 ttcgttgcga aggaaacctt ccttgtcagc atcgagaata gctacgaggc tcacttcagg
     1441 aacgtcaatt ccttcacgga gcaggttaat tccgaccaag acatcaaaga cacccaagcg
     1501 caggtcacgg ataatctccg tccgttccaa ggtcttgata tccgagtgca tgtacttgac
     1561 cttgataccc atttccttga agtagtcggt caaatcctct gccattttct tggtcaaagt
     1621 tgtgataaag gtacgctcat ttttttcaac gcgggcattg atttcaccca agaggtcatc
     1681 aatctgtccc atagtcggac ggacttccac ctctggatcc aagagtcccg ttggacgaat
     1741 gatttgctca atcactgtct cggtctgttc attttcatag tcaccaggtg tcgctgaaac
     1801 gtaaacaatc tgatgaacgt gactctcaaa ctcctcccga cggagaggac gattgtccaa
     1861 agcagacggc aaacggaaac cataattaac cagcatttct ttacgcgaac ggtctccatt
     1921 gtacatgccc ttgatttgcc ctatggtcat atgactctcg tcaatcataa tcaagaaatc
     1981 atctgggaag aagtcgagaa gcgtataagg aggctctcct tcgctccgtc catccatgtg
     2041 gcgagaataa ttttcaaccc cattggtata gcccatctca cgcaacattt cgatatcata
     2101 ctctgtccgc tgtttcaaac gctgggcttc aagcagttta ccttcctttt caaagacagc
     2161 taattgttct tccaactcgg cctgaatctt tgcaatggca acttccatgt ggtcgtcatt
     2221 ggtcacaaag tgtgtcgctg ggaaaatcgc taaatgatcc acttctccca acacctgacc
     2281 tgtcagagcc tcaacttcac gaatacggtc aatttcgtct ccaaaaaatt ctactcgaaa
     2341 ggcatgttca tctcgggaag ctgggaaaat ctctaccaca tccccacgaa cgcgaaatct
     2401 tccgcgttgg aaatcaatat cattgcgttc aaactgaata tcgaccaagt cattcaagag
     2461 tttatcacga gaaatctcta gaccaggacg gagactaacg acactatcag cgtattcctt
     2521 gggcgaaccc aaaccataga tacaagagac tgaggccacg acaataacat cattacgctc
     2581 caaaagggct gaggtagctg agtggcgaag cttgtcaatc tcgtcattga cagaactatc
     2641 cttctcaata taggtatcgc tagaagggac ataggcctct ggctggtaat aatcatagta
     2701 ggatacgaaa tactcaactg cattttcagg gaaaaattcc ttaaactccc catagagctg
     2761 accagccaga gttttattgt gggcaataac cagagttggt ttattgactt tagaaatgac
     2821 ctgactcata gtatacgtct tccctgttcc agtcgccccc atcagaatct gagctttttc
     2881 tcccccctca atgttatcca ccaactgctc gatagcttgg ggttgatctc ctgatggttg
     2941 atattttgat actagtttaa attgattatc tgtaatgtga ttgatcataa gaatcctctc
     3001 tccatgtgct attcctattt tagcatactt atagtatttt cacgaagaaa aggatggacc
     3061 gaagtcacat cctttcattt tctttcttta atttattagc aagatagaca atcagcagta
     3121 gtaataccag acttgtcata atggaacctt ctatgccaaa agaaccacct gatagccaat
     3181 cttgattgcc ttgtggtaaa aaggtcatca gagacgttcc tgacggttga ccactaacta
     3241 aaatcccaaa gagattaccc tgagcaaaat tccaagcacc atgaatacct gcaacacccc
     3301 aaactgtatc agttttgaga aggtaaagag ccatggcaac tccgaataaa aagagattta
     3361 ctagagatag aggggtgagg ccagaattgc ccatatgaag cagggtaaag aacaggctag
     3421 atataagaat agctagtttt agattggttc ttgaggccaa ttgaggaagt agccaagcac
     3481 gggccaccac ttcttctgct gtcccctgta aaatccaaaa tgggatagta aagacgacaa
     3541 aggcaagaga ataaggattc aagtgaatgg attccaaacg atattgacct aagaccacca
     3601 aacctaacaa ggtcagaaga aaaagtgcca gacctagact aaatcctttc agaagattgc
     3661 tgaggaaatt ctctctataa aatcccaagg ttcgaatagg tcttttctca acttttcttg
     3721 tccatctgaa cacagtgtta agaataaaac caaaggccag taatcctaaa attaaacgaa
     3781 agtcacttgt tttatccgtc aagctctgat gcaaggtctg caagtagctt gcaagatttt
     3841 gaccagcctc tccaaaattt ctagcaagtc cgatgagagc taacaagcca ataccataca
     3901 aagtaaaagc cacaaactct cctatgaaga caaaaacaaa ggctaacaag gggcttgtgt
     3961 aaatgtttaa actcattttt gaagcttgga agtctttaaa tattcttttg ttcttcatat
     4021 ccccgtcctc ttttcttcta tatatactat tattatagca ctttttaata gcaattcaaa
     4081 gaaaggaaaa aatcaatgtt atattttctg acacgaaaaa tataaaaatt tgcctttttt
     4141 tactttttct gatataatga gagaatattc ggaaaaggag actaaaaatg aagaaaaaat
     4201 ttctagcatt tttgctaatt ttattcccaa ttttctcatt aggtattgcc aaagcagaaa
     4261 cgattaagat tgtttctgat accgcctatg caccttttga gtttaaagat tcagatcaaa
     4321 cttataaagg aattgatgtt gacattatta acaaagtcgc tgagattaaa ggctggaaca
     4381 ttcagatgtc ctatcctgga tttgacgcag cagtcaatgc ggttcaagct gggcaagccg
     4441 acgctatcat ggcagggatg acaaagacta aagaacgtga aaaagtcttc accatgtctg
     4501 atacttacta tgatacaaaa gttgtcattg ctactacaaa gtcacacaaa attagcaagt
     4561 acgaccaatt aactggcaaa accgttggtg ttaaaaacgg aactgccgct caacgtttcc
     4621 ttgaaacaat caaagataaa tacggcttta ctattaaaac atttgacact ggggatttaa
     4681 tgaacaacag cttgagtgct ggtgccatcg atgccatgat ggatgacaaa cctgttatcg
     4741 aatatgccat taaccaaggt caagacctcc atattgaaat ggatggtgaa gctgtaggaa
     4801 gttttgcttt cggtgtgaaa aaaggaagta aatacgaaca cctggttact gaatttaacc
     4861 aagccttggc tgaaatgaaa aaagatggta gtcttgataa aattatcaag aaatggactg
     4921 cttcatcatc ttcagcagtg ccaactacaa ccactctcgc aggattaaaa gctattcctg
     4981 ttaaggctaa atatatcatt gccagcgatt cttcttttgc accttttgtt ttccaaaatt
     5041 caagcaacca atacactggt attgatatgg aattgattaa ggcaatcgct aaagaccaag
     5101 gttttgaaat tgaaatcacc aaccctggtt ttgatgctgc tatcagtgct gtccaagctg
     5161 gtcaagccga tggtatcatt gctggtatgt ctgtcacaga tgctcgtaag gcaacttttg
     5221 acttctcaga atcatactac actgctaata ccattcttgg tgtcaaagaa tcaagcaata
     5281 ttgcttctta tgaagatcta aaaggaaaga cagtcggtgt taaaaacgga actgcttctc
     5341 aaaccttcct aacagaaaat caaagcaaat acggttacaa aatcaaaacc tttgctgatg
     5401 gttcttcaat gtatgacagt ttaaacactg gtgccattga tgccgttatg gatgatgaac
     5461 ctgttctcaa atattctatc agccaaggtc aaaaattgaa aactccaatc tctggaactc
     5521 caatcggtga aacagccttt gccgttaaaa aaggagcaaa tccagaactg attgaaatgt
     5581 tcaacaacgg acttgcaaac cttaaagcaa acggtgaatt ccaaaagatt cttgacaaat
     5641 acctagctag cgaatcttca actgcttcaa caagtactgt tgacgaaaca acgctctggg
     5701 gcttgcttca aaacaactac aaacaactcc ttagcggtct tggtatcact cttgctctag
     5761 ctcttatctc atttgctatt gccattgtca tcggaattat cttcggtatg tttagcgtta
     5821 gcccatacaa atctcttcgc gtcatctctg agattttcgt tgacgttatt cgtggtattc
     5881 cattgatgat tcttgcagcc ttcatcttct ggggaattcc aaacttcatc gagtctatca
     5941 caggccaaca aagcccaatt aacgactttg tagctggaac aattgccctc tcactcaatg
     6001 cggctgctta tatcgctgaa atcgttcgtg gtggtattca ggccgttcca gttggccaaa
     6061 tggaagccag ccgaagcttg ggtatctctt atggaaaaac catgcgtaag attatcttgc
     6121 cacaagcaac taaattgatg ttgccaaact ttgtcaacca attcgttatc gctcttaaag
     6181 atacaactat cgtatctgct atcggtttgg ttgaactctt ccaaactggt aagattatca
     6241 ttgctcgtaa ctaccaaagt ttcaagatgt atgcaatcct tgctatcttc tatcttgtaa
     6301 ttatcacact tttgactaga ctagcgaaac gcttagaaaa gaggattcgt taatggcaaa
     6361 attaaaaatt gatgtaaatg atttacacaa gcactatgga aaaaatgaag tcctaaaagg
     6421 aattacgact aagttctatg aaggagatgt tgtttgtatc atcggtcctt caggttctgg
     6481 taagtcaact ttcctccgta gcctcaatct tttagaagaa gtcactagcg gtcacatcac
     6541 tgtgaacggc tatgatttaa ctgaaaaaac aaccaatgtt gaccacgtcc gtgaaaatat
     6601 cggcatggta ttccaacact tcaacctctt ccctcatatg tctgtattgg acaacatcac
     6661 ctttgctcct attgagcaca agttgatgac taaggaagaa gctgaggaat tgggaatgga
     6721 gttgcttgaa aaggttggac tagcagataa agctaatgcc aatccagata gcctatcagg
     6781 tggtcaaaaa caacgtgtgg ccatcgctcg tggcctagca atgaatccag acatcatgct
     6841 cttcgatgaa ccaacttctg cccttgaccc tgagatggtt ggagacgtac ttaacgttat
     6901 gaaggaattg gctgagcaag gcatgaccat gattatcgta acccatgaga tgggatttgc
     6961 tcgtcaggtt gccaaccgcg ttatctttac tgcagatggc gagttccttg aagacggaac
     7021 acctgaccaa atctttgata acccacaaca ccctcgtctg aaagagttct tagataaggt
     7081 cttaaacgtc taaactcaaa ctgtaaggat ttccttgcag tttttctacc tcgtattgga
     7141 atttttgatt tttcggaaaa ttatgttaga attaagttta tgaaatgagg tttcctcata
     7201 cctagcaaga ctaggaataa aaatagaaat taggtagcta gatgtcatct aaggttattg
     7261 ttacaatttt cggtgcgagt ggagacctgg ctaaacgcaa gctctaccct tcccttttta
     7321 gactatataa atccggcaat ctttccaagc actttgccgt tattggaact gcccgtagac
     7381 cttggagtaa ggaatatttt gaatctgtag ttgtcgagtc catccttgat ttggcagata
     7441 gtaccgagca agcccaagaa tttgctagcc acttctacta tcaaagccat gatgtcaatg
     7501 atttggaaca ttatattgct ttgcgtcaat tacaagctga gcttaatgaa aaataccaag
     7561 ctgaacacaa taagctcttc ttcttgtcta tggcacctca gttctttgga accattgcca
     7621 aacacctcaa atctgaaaac attgtcgatg gcaaaggttt tgagcgcttg atcgttgaaa
     7681 aaccatttgg tacagattac gcaactgcaa gcaagttgaa tgacgaactc ctagcaacat
     7741 ttgacgaaga acaaattttc cgtattgacc attatcttgg taaggaaatg atccaaagca
     7801 tctttgcagt tcgctttgca aacttgattt ttgaaaacgt ttggaacaag gattttatcg
     7861 acaatgttca aattaccttt gcggagcgct tgggtgtaga agaacgtggt ggctactatg
     7921 accaatccgg tgccctccgt gacatggtcc aaaaccacac tctacaactt ctttcgctcc
     7981 tcgccatgga caaaccagca agcttcacaa aagacgagat tcgtgctgaa aagattaagg
     8041 tctttaaaaa cctctatcat ccaactgatg aagaactcaa agaacacttt atccgtggac
     8101 aataccgctc tggtaagatt gatggcatga aatacatctc ttatcgtagc gaaccaaatg
     8161 tgaatccaga atcaacaact gaaaccttta catctggtgc cttctttgta gacagcgatc
     8221 gattccgtgg tgttcctttc tttttccgta caggtaaacg actgactgaa aaaggaactc
     8281 atgtcaacat cgtctttaaa caaatggatt ctatatttgg agaaccactt gctccaaata
     8341 ttttgaccat ctatattcaa ccaacagaag gcttctctct tagcctaaat gggaagcaag
     8401 taggagaaga atttaacttg gctcctaact cacttgatta tcgtacagac gcgactgcaa
     8461 ctggtgcttc tccagaacca tacgagaaat tgatttatga tgtcctaaat aacaactcaa
     8521 ctaactttag ccactgggat gaggttggtg cgtcatggaa gttgattgac cgtattgaag
     8581 agctctgggc cgaaaatggt gccccacctc atgactataa agctggaagc atgggacctc
     8641 aagccagctt tgacctactt gaaaaattcg atgccaaatg gacttggcaa ccagatatcg
     8701 cctatcgtca agatggtcgt ttcgaataaa aaaatcctgc aagtttgtac cttgcaggat
     8761 ttttgcttct gattagatta agccttccaa gagacctttc ataaagtttt ctgagttaaa
     8821 ctctccaata tcatcgattt tttcaccaaa accaatcaat tttacaggaa tattgagttc
     8881 ttcacgaatg gctagaacca cacctcctcg agcagttcca tcaatcttag tcaaaacaat
     8941 tcccgttaaa ggtgtgattt tcgaaaattc tttggcctgt actagggcat tttgacctgt
     9001 tgatgcatca agtgccaaga aggtttcatg tggtgcttct ggcacaacac gtttgataat
     9061 acgaccaatc ttttccaact cagccataag gttatcctta ttttgcagac gaccagcagt
     9121 atcaatcatg agaatatcga taccttcagc cacggcacgt tccataccat caaagaccac
     9181 gctggctgga tcagcttttt caggtccagt tactactgga acatctactc gtcggcccca
     9241 ttcagctagc tgagctactg cacccgcacg gaaggtatct gctgcaacca gcatgacctt
     9301 cttaccagtt cgtttgtagc ggtgggctag ttttccaata gaagttgttt tcccaacacc
     9361 attcacacca acaaagagca taactgtcaa gttatcttgg aagtggatgc tttcatcgta
     9421 gctaccatcc ttttcataaa gctcaaccaa tttctcaatg atgacacgac gaagtgcatc
     9481 aggtttcttg gcattttcaa gcttggcttc gtaacgtagt tcctccgtta agttagaagc
     9541 gacttggaca ccaacatcac tcataatcag cagttcttcc agttcctcga aaaattcttc
     9601 gtcaacagag cggaagttag caaagaaggc gttcaagcga gcaccgaagc ccgtacgagt
     9661 cttcttgaga ctgcggtcat atttttcctg aacagtttct tctgtttgag gcctttctgg
     9721 ttcaagaact tcagaattat tttcttctat agttccttcg tgctcaagct tctcttcctc
     9781 tggtaattct tctgagtttg gtaattcttc tatttcttct tgagaaaccc ctacagctgg
     9841 ctctgaatcc tgactttctt caactgtgtc ttggatttcc tcctcttgga acacagcttg
     9901 ttcaacaatt tcaacctctg cttcttcctg aggaacttcc tcaacttctg tgaaggtagg
     9961 atcaacatct tcagacaaat caagattttc cagagcttct tttacaactt cttcgatttt
    10021 aggttcttct ttttttccga atagacggtc aaacaatccc atatcttagt tctcctttag
    10081 cacatattct tcgatagccc aggcgacagc ttcctcatcg ttggtcatcg gcgttactac
    10141 atttgcggct gcctttactt caggaacagc gttttgcata gcaacaccaa gacctgccca
    10201 ttcaatcata gaaaggtcat tggcctcgtc accacaggcc ataacttggc tttggttgat
    10261 tccaagatgg ctgattagtt ttgccaaacc tgttgcttta tgaacattct ttggtgacca
    10321 ctctagcaac atttcacgtg atttaaagat ttcatattgg tcaaacaatt ctggagaaat
    10381 cttctgaatg gctgcatcca agggttcttg agcaaaggca gtcacgcatt tgttgtaggt
    10441 catttgacta gacaggtctt caaagtcaac tggaacaaaa gtcaaagctg gattgaattt
    10501 ggcataaaga ctttcttggt ccgattggat ttgataaact gttccttctg agatggcatc
    10561 aagtggcagt gataatttct ctgttttctc atacaagcgt gccacatcag catatgaaaa
    10621 gactgtttta tcaaggattt cacctgtatt tttctgaacc aaaccaccat taaaagtaat
    10681 ggtatactca tcttcctgac cgtcagtccc taactcatgg agaaagaagt ccatggcttt
    10741 taagggacga ccagttgtca atacgacctt gataccacga tcacgcgcag ctttcaaagt
    10801 tgccttggtg cgatccgtca gccttttatc agtagtcagc aaggtaccgt ccaagtccaa
    10861 tgcgattaat tttatatctg ccattataag ccctccatat aagctataac cgactggtcc
    10921 ttatggtgac caatcacagt ctttgctaat tctaaaatct ctggtcgtgc attttcagga
    10981 gctacaggat gtcccacaac ctgcatcata tgtaagtcat taagattgtc tccaaaagcc
    11041 atgacctgat ccattgtgat gccaagtttt ttagctaatt caacaatagc tacaccctta
    11101 tcgacatagt ccagaacaat atcaatagat tcaaagccag ttgtcatagc cttgacacca
    11161 gggacattat cattgaccca agcttcacca gcttctagcg tttcttctgt gaagttggtt
    11221 gtaaatttga aaatgtcatc tgtgatatct tccaaactcg ctactttttg gatattttca
    11281 ttataatgct gactcacttt caaataggtc tcatcaaccg tatctagaac atatgaaccc
    11341 ttcttacccg tcaagagcag tttattgata tctatataag gtgacgtttt cagcttttca
    11401 aaagttgcca gataaaagtc acgagacata gtcgcttcat acaagtcctg accttgatac
    11461 tctaccaaac tgccattttc cgcgatgaaa ataatgtcat cacgaacacc agcaaataat
    11521 ttttccagag acagaaatcc ccgacccgaa gccaccgcaa agtaaatccc tttttccttg
    11581 taggaaacca agagagactt gaggcggtcc atatcaaagc gcccattctc atctaggaag
    11641 gttccgtcca tatccgttgc tactagttta attgtcatcc ttcaatactt tctaaatctt
    11701 ttaacttaac tgaaacaatc tttgaaacac ccgattcttg catggtcact ccatagatgg
    11761 aatcggccgc tgccatggtt cccttacggt gggttacgac gataaactgg ctgtccttgt
    11821 caaagcggtt gaggtaatcc ccaaaacgtt taacattggc ttcatccagc gcagcttcca
    11881 cctcatccaa gatgacaaaa ggaatggtct tgacacgaat aatggagaaa agcaaggcaa
    11941 gagccgatag ggctttttca ccaccactca tgaggttaag cgactggatt ttcttacctg
    12001 gaggttgaac agaaatctcc acaccagctg ttaaaaggtc gccctcagtc aatatcaagt
    12061 ctgcctgacc tccgccaaac atctgcttga aggtcacttt aaaggactca cgaatagctt
    12121 caaaggttga tttaaagcgt tccttaacct catcattcat ctttgtaatg gtttcaagga
    12181 gcagattttt cgctgacaaa atatcatctc gctgactatt tagaaagtcc agacggttgt
    12241 gaacttcttc gtaccggtca atagcttcta tattgacagg acccagtgag cgaatagcct
    12301 tctctaaatc cttaacttct tgctctgcca gattgaggtt ttccaattca tgcgcttttt
    12361 ctagagcttc agtatagcta atctggtact ggtctgttaa ttgactttgt agatggcgca
    12421 agcgctcgct gaccttttct ttcttagctt cagcacgtgt ttgcttgcga atccactcct
    12481 cattctgctg gcgagcctga tccaaatgac tagcaatatc atccagctga ccttctatat
    12541 catccaactc aaactgtttg cgaatcaaac cttgttggag gttcgttttc tgagttttgg
    12601 attcttccgc ctgttgactg agcaattctg tatcaacctt ctcaagattg tcaacctttt
    12661 cttgaagaag gcgctggatt tcctcttgtt caaaatcaag attgtccaat tccttgccta
    12721 agcgttcaat atcagcaact tcataacgtt tttgcccttg cagttctgtc ttaagcaaac
    12781 gagcttgcgc tagctcttcc tgcaagtttt gatagcgttc ttggatggca tttttattag
    12841 acttaatctc ttcaatctca gcttccagat tttgcttgtc actggcgatt gcagcaagac
    12901 gctcttggca tttttcctta tccgcttgcc aatctccctc ggaaagacga tctatttcct
    12961 cttcttggag tttccaaaga gtttccagtt cttcaacttg ctgactagtt tgctgataag
    13021 cgagggacaa gccttgctcc tgaatacgtg cctgctctcc ttgagattta atagcttcta
    13081 atgactcggt caatctggcc atctcatctt gcaaggtctt caaagccact tcttctgaac
    13141 ccaagcttgc ttcttcttca gcaatttctt tttgtaattg ctccagttct ggcttgatga
    13201 agatgctgtt gttctgacga ttggctccac ctgcatagga accacctgta cgaagctctg
    13261 tcccatccaa tgtcaccatg cgaacctgat aacgaacttg tcgagcagct tcacgcgcat
    13321 gttctacggt atcaaagata gccgtcgtag ctagcaagtt cttgaaaatg gcttccagtc
    13381 tagtatcaaa agtcaccaac tcatctgcca tcccaaggaa acctgggctt acagcgatag
    13441 catcttggtt ctgactagaa atcgtacgcg ccttaatagt ggtcaaagga agaaaggttg
    13501 cacgaccggc tctgtttcgt ttgaggaaat caatagcttt ggttgccgac tcttcatctt
    13561 ctacgatgat atgctggcta cttgccccta aggcaatctc tagggcagtt tgataataaa
    13621 catcaaaggt cagatgctca ctgactgcac caataatccc acctaggcga tctttttctt
    13681 ggagaacact cttaacacct gcataaaagt tgctatgatt tctcaggata ttttccaaac
    13741 tttgagctct ggcctgcttg tttttgagac tatccagacg gtcaaagagt tgagtttgtt
    13801 gagcttgata ggaagttttc tgctcctctt gctccttggc aatagcttgg tagtcagcca
    13861 ataatttctg aacctgctcc ttggcagttt caagctcttc cttttgctga ctagccttct
    13921 ctttagctat agctaattgc tctttcagct tttctagttg atctgcttgt ttttgagaaa
    13981 gctgacgact attttccaac tcattctcaa tacgggtcaa ctggtttgag acatccgctt
    14041 cttcttgtaa aagagctaca aagcgttcac gtaagagctc aatcatctga tcaggatcgt
    14101 ctgagaaagc cagcaattca gcttctaaac gattgagttt ttgattattt tggactagat
    14161 ttccctctaa cagagctaaa gagctttctt tatcagactt ttctttgctg agtgaatttc
    14221 tcttatcctc caaagcagcc aaacgggctt gtgcctcctg ttgattcagg gccacttgct
    14281 cggactccag tttcgatagg gctaattttc tttctaaatc actaatcaga ctagtcaagt
    14341 ccatcaaact gccttggtct ttggccattt cagcctgtaa atcttggcgt tgctttttaa
    14401 gagtttgatt ttcttcttct aatttttcac gcttttggta ataactcatc aagagttctt
    14461 gaacctgagc caactcttct tctgtcgact ctagttctgc cttattttcc ttgatttgag
    14521 caaccagaac gtctaaataa atagccttac gttgtccttc caagtctaaa aacttacggg
    14581 cattctcagc ttgcttctca agaggcttga tttgattatc caactcgtag ataatgtcct
    14641 ctaagcggtc cagattatcc tgagtttgtt gcagtttact ctcagtttct tttctacgag
    14701 tcttgtattt taaaactcct gcagcttctt caaaaatagc ccggcgttcc tcaggcttag
    14761 aattaaaaat ctcctcaacc ttgccttggg aaatgataga gaaggaatct cgtcccaatc
    14821 cagtatccaa gaagaggtca tgaatatcac gcagacggac tttcttgccg tcaatcttgt
    14881 attcgctatc tccactacga tagatatggc gttccaccct gatttcttga cctgcatcct
    14941 tgataaatcc gtcatgatta tccagagtca caactacaga agcataattg agcggtttgc
    15001 gactttcggt tccagcaaag atgacatccg gcatcttgcc cccacggaga ctcttgacac
    15061 tagactcccc caaagcccaa cgcagacttt ctgtaatatt ggactttcca gatccattgg
    15121 gtccaacaac tgccgtcaca ccttggtcaa aaacgacctt ggtcttatca gcaaaagact
    15181 tgaacccctg aatttcgatt tcctttaaat acatgaatcc agccccttct caacggcatt
    15241 tttggcagct tcctgctctg ctaatttctt agaacgacct tggccttgac cgatgctctt
    15301 accttcaaca agaacttcta catcaaagac cttatcgtga gcaggccctg tttcagaaat
    15361 cacctgataa cgaatagcca catcaccatt gacctgaagc aactcttgga gatgggtttt
    15421 atagtctgta atcatctcaa actcgcctgc ttcaacctta ggaatcatga cttgatagat
    15481 aaattccttg accttggcca catccttatc caaaagaagg gcaccaagaa aggcttcaaa
    15541 ggcatcacca agaatggtgt cacgattgcg accaccagat ttttcttccc ctttacccaa
    15601 cttgataaac tggtcaaact ggcaatcacg cgcaaaacca gctaaactct cctcacggac
    15661 aatcatagca cggagttttg ataggtcacc ttcaggcttt ttaggatatt ttttatatag
    15721 atattctgaa atcaataact gtagaacagc gtctcctaaa aattccaagc gttcattgtg
    15781 tgaaattttt aagaggcggt gctcattggc ataactcgta tgagtaaagg cagtttccag
    15841 taaatttttg tctgcaaatt cgattgcaaa atgattcttt agtacagttt gtaattcttt
    15901 cataccaacc tctttctaac tgataatagt cctttttatt atatcaaaaa aagccccctg
    15961 agtcactcta aaacgggact ggaaagcatt tgggaattct ttagacagag attctcagtt
    16021 ttagcgacaa atttgggtca ggataaagaa aaaagcccta ttaaaggctt tttaggatgt
    16081 ttacatccac cctgagggaa tcgaaccccc atctcaagaa ccggaatctt acgtgatatc
    16141 cattacacta agggtggaaa cttgttttat tataacagaa atttgctcta ataacaagtt
    16201 ttttggtcaa agaccccgtc ttagtgggaa gcatccccat tccagatgga gtttttcacg
    16261 atcacataat caacgtgttt aaggtcagca acctgacgtc cacctgcata agaaatagca
    16321 ctttgaaggt cttgttccat ctcagttaaa gtgtcttgca gatgaccttt agcaggaagc
    16381 aagatacgtt tgccttccac atttttgtaa gcaccttttt gatattgtga ggctgaacca
    16441 taatattctt tgaactgttc accatcgact tcaatcgttt tccctggact ttcaatgtgt
    16501 cctgcaaaga gggaaccaat catgatcatg ctagcaccga agcggataga cttagcaata
    16561 tcaccgtgag tacgaattcc tccatcagcg ataatcggtt tacgcgcagc cttggcacac
    16621 cagcgtagag cagccaactg ccaaccacct gtaccaaaac cagtcttaac cttggtgata
    16681 caaaccttac caggaccgat tccgacctta gtagcatccg caccagcatt ttccaattca
    16741 cgcacagctt ctggtgttcc cacatttcca gcaatgacaa aggtatctgg caattctttc
    16801 ttgatgtgtt gaatcataga aatcacgcta tccgcatgac catgagcaat atcaatagtg
    16861 atatactcag gagcatcagc cttgagctgg ctaacaaaat catactcata atccttaaca
    16921 ccgacagaga tagaagcaat gagcccttga tcgtgcattc gtttaataaa aggaatgcgt
    16981 cctgcctcat caaaacggtg cataatgtag aagtaaccac ctttagccag ttgctctgct
    17041 acattttcat ccaaaatcgt ctgcatattc gctggcacaa caggtagttt aaaggtgtga
    17101 tttcctaaag tgacacttgt atccgcttct gcacggcttt taatgacaca tttatttgga
    17161 atcaattgaa tatcttcgta atcaaaaatt ggaaattcat ttaacatatc gatgtctcgt
    17221 ttcttttgta atgacctacc tatgctcttg catcactacg ccttttccga cgtttcctta
    17281 atttattata aaccaaagta cagtttttgt caaattattt tatgaattaa aatatatcgt
    17341 tcgggtttta cttgtgttaa aaataaaaga aagaggggaa attattttct ccccacttct
    17401 tcatcaataa tcgctttaaa attttcttct gaattttcca tcattttaca aaatgtacta
    17461 tagaatgagg cattctgagg gattcgaata gaccacttct tcaattgagc tccatagcca
    17521 gctacttttc ctatttcact atttactgac tgctccatac taggaaaaat cagtccagcc
    17581 ttctcagctt ttaaaatata agaataggaa atcagctgga ataagtcctc acggttgatt
    17641 cctttttcag tcaattccag ttttttatat tttgcatcta gaacaatctt tcgttctctg
    17701 tcataaaaat ctggatatac ttttcgtttc ccaacagaaa atactgaaat tccatccgtc
    17761 ttatccttat ttctgggatg tacaaaacct tttggcaaca aggtgtaaac atactcttcc
    17821 caaagccagg caacatcaaa gagaatacca tagatttttt gatcttgata ccctaaaccg
    17881 tgcttttctt ggtttaggat catcagacaa agttcttgta agtttctgta ctcgtgaaag
    17941 tatgcatgac gtataggttt agattgattt ccccgaataa tcttagcacg atcagctagt
    18001 ttataagagg gcgttacacg cacgatttca gatacgtttt cacgactagt tgagagatta
    18061 tctagtaccc cttgaccaat gcttttctga ttcttaatgt attcaatagt gtgacggacc
    18121 aactgcatga ggggattatc ataggtgaac tctctcgttg cgtaggcaat atttcccgtg
    18181 aaaggaagat ttttcttgag atggtttctt acatcaatca ctcccttaac atgactgtcg
    18241 ttatgagaaa atcgatgata ttccttataa agaccttttc gaatagcagc ttgtagatac
    18301 ttgggaaaga gatacaccaa aagttgataa agcctctctt cacgagacaa agcaacatct
    18361 aaactagtga gattgatata aagaaccttg tttaagagat aatgcaaaaa atggtcatta
    18421 ctctcatcag aaaatcgtga ggaaatcgtt aatctttcct gaccatatcc aagaaaacca
    18481 atcacgttcc ctgtcttgat tttctgattg actgtttcaa aaatcttttg gtccttatcc
    18541 aaatcaggag tatgagtcaa atcatttgga aaaatgaaaa tacgttcatc ttgggataga
    18601 ctttccaagg ttctgtctaa aagaagattg cttagtttag gatattcttc aacaaatttt
    18661 tctttaataa tcttgtgttg attatcagta atccgcatca tcgttttcat cgccttcatt
    18721 gtcatcagct actgcctgat ctttttgctc attatttgtc agttcaaatg cttttttcaa
    18781 agtttccaaa gtttcaacct catcataaga acctcgcaag tagtcttcta ggagaggctt
    18841 aatataatca gaccagagta attcatagtc aaaatctaca tccttcaact taagaaaata
    18901 acttggtcca atatgataat gactgtttaa ttcctgaaca ttttcgatag cagcgttcaa
    18961 gtttcttaga cgaatttttg cttcttctgc atggatattc agctctttat ccaacatgcc
    19021 aacttgaccc tcggcagtaa cttcaacaaa acgaaaacga cgacgcatag caaaatcaaa
    19081 ggtatccact gaacgatcaa tgtcattcat agttccgatg atgtagacat tttcggggat
    19141 atagaacttt tcatcagttt cgtgtagatt tgcatattgg gtagaaacac ttcctttttc
    19201 accacgatag ccagggtcga tagagaaaaa gagttcgcca aaaatcttag aaatctcccc
    19261 acgattgatt tcatcgatga tgaagacgaa tttcttatca gtatcaattt ctgttgggga
    19321 aacatagtct ttcaaaccaa atctctttct caatgtttct aggacagttt ttccaccact
    19381 tttgtagtat tcttgcttat tataattttt atctttatac aactcgtaaa catatttgct
    19441 aggtagtgac catcctggaa caccactatc ataatttact gacaaatttt gtctactatt
    19501 aacagataag taagatgttt ttgttatata ttctttttct tcagcaacat ttatatattc
    19561 taagtaagaa tcccaagcct catcaaaatt atcttgtcct ccaatcaatt gggtttcttt
    19621 tgctttctga caaaaatctt taaaaatacc gtcctgtagc ctaaactcaa tagctccatc
    19681 cccatttgat actggtctta aaccttctac aaaatccgta taatcatagg atgggtgaaa
    19741 ttgtacaaat ccgatttggt cttcgttgcc atccgttaat tctttggcaa tttctttagc
    19801 aagataagtc tttcctgtgc caggagcacc acggaggatg aggtttttgg attgtaataa
    19861 gatattctta tactcgttga tattttctga catgtttatc tcttcctttt ctgattctct
    19921 ataaaaacta gtgaaattat cataaaactc ttttaaaata tcgttaggtt cagcagttga
    19981 ttccaactct aagtccttga caaagtattt ataatctaaa tcttcatctc gattattact
    20041 ataccttttt actattttaa attctgtgag tttaaatctc tgaaaaccac atcttatatt
    20101 tatccatgag ttatccatgt cactcagccg ataaccaaag taaggtgatt taatatatcc
    20161 attaccactc tttggaccaa aatgacctgt gttaagcatt tcaactttgt acagaatacc
    20221 ctcaatagtc agagcagggt aaatatgttc agctccatct aatttttgag aacgttta
//
LOCUS       DAVKMO010000034        20163 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVKMO010000034 DAVKMO010000000
VERSION     DAVKMO010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20163
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.034"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            45..1351
                     /locus_tag="VW361_001394"
                     /pseudo
     CDS             45..1351
                     /locus_tag="VW361_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1402..1560)
                     /locus_tag="VW361_001395"
     CDS             complement(1402..1560)
                     /locus_tag="VW361_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744421.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(1570..2880)
                     /gene="obgE"
                     /locus_tag="VW361_001396"
     CDS             complement(1570..2880)
                     /gene="obgE"
                     /locus_tag="VW361_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU9744422.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            complement(2944..3078)
                     /locus_tag="VW361_001397"
     CDS             complement(2944..3078)
                     /locus_tag="VW361_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU9744423.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            complement(3137..3313)
                     /locus_tag="VW361_001398"
     CDS             complement(3137..3313)
                     /locus_tag="VW361_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9744424.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            complement(3344..4669)
                     /locus_tag="VW361_001399"
     CDS             complement(3344..4669)
                     /locus_tag="VW361_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU9744425.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKIKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            complement(4685..5728)
                     /gene="cpoA"
                     /locus_tag="VW361_001400"
     CDS             complement(4685..5728)
                     /gene="cpoA"
                     /locus_tag="VW361_001400"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU9744426.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            complement(5843..6172)
                     /locus_tag="VW361_001401"
     CDS             complement(5843..6172)
                     /locus_tag="VW361_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9744427.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            complement(6186..7295)
                     /gene="rpoD"
                     /locus_tag="VW361_001402"
     CDS             complement(6186..7295)
                     /gene="rpoD"
                     /locus_tag="VW361_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU9744428.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            complement(7298..9058)
                     /gene="dnaG"
                     /locus_tag="VW361_001403"
     CDS             complement(7298..9058)
                     /gene="dnaG"
                     /locus_tag="VW361_001403"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU9744429.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQDLYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKRSSGKASEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAATLKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGKLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            complement(9148..9906)
                     /locus_tag="VW361_001404"
     CDS             complement(9148..9906)
                     /locus_tag="VW361_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744430.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEELTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            complement(9903..10769)
                     /locus_tag="VW361_001405"
     CDS             complement(9903..10769)
                     /locus_tag="VW361_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9744431.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGHMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLLTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            complement(10838..11842)
                     /locus_tag="VW361_001406"
     CDS             complement(10838..11842)
                     /locus_tag="VW361_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9744432.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEVQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     misc_binding    complement(11955..12172)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(12255..14951)
                     /gene="ppc"
                     /locus_tag="VW361_001407"
     CDS             complement(12255..14951)
                     /gene="ppc"
                     /locus_tag="VW361_001407"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU9744433.1"
                     /translation="MSLQKLENYSNKSVVKEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     gene            complement(14971..16200)
                     /locus_tag="VW361_001408"
     CDS             complement(14971..16200)
                     /locus_tag="VW361_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9744434.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGSWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            complement(16356..16658)
                     /locus_tag="VW361_001409"
                     /pseudo
     CDS             complement(16356..16658)
                     /locus_tag="VW361_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(16763..17011)
                     /locus_tag="VW361_001410"
     CDS             complement(16763..17011)
                     /locus_tag="VW361_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEU9744435.1"
                     /translation="MCKPISIELCDDEVHSLHEWIDGRDAIDSILAYSENQQYTYGVE
                     AGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            complement(17293..17880)
                     /locus_tag="VW361_001411"
     CDS             complement(17293..17880)
                     /locus_tag="VW361_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEU9744436.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            complement(17959..18387)
                     /locus_tag="VW361_001412"
     CDS             complement(17959..18387)
                     /locus_tag="VW361_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744437.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            complement(18650..18772)
                     /locus_tag="VW361_001413"
                     /pseudo
     CDS             complement(18650..18772)
                     /locus_tag="VW361_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(18870..19106)
                     /locus_tag="VW361_001414"
     CDS             complement(18870..19106)
                     /locus_tag="VW361_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744438.1"
                     /translation="MKIINGICRYIFDSKGFATIEVEIFLDSGDTGIGAAPRGSTTGR
                     YDIQYNEYYPRGNNFSPIPDGHIEFFRLYNICSG"
     gene            complement(19171..20136)
                     /locus_tag="VW361_001415"
     CDS             complement(19171..20136)
                     /locus_tag="VW361_001415"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU9744439.1"
                     /translation="MAIIKKIVVLYGGLSEEREVSENSAKEISKSLLTLGYDVISIDL
                     SQDCSYEIGEIEKSERGLNEQKVEIGSGIIDVCRKVDIVFLATHGGIGENGKLQAIFD
                     VEKIDYTGNSFLSTAISMDKKLSKIVASSVGIKCASNLMVDRIQANDFPIVIKPIRSG
                     SSKGIKIFQNKKQFDIYYKEHPELGSLFVEKYIKGREFSVGILGETVLPVIEIKVKNG
                     FYDYNNKYTVGAAEEVVPAKISEKLTHTLQKSAYKIHKALGFNVYSRTDFIVDEKGDV
                     YFIESNSLPGMTKTSLLPQEAKAAGIDFPNLCERIIELSREIRSQ"
BASE COUNT         6019 a         4442 c         3350 g         6352 t
ORIGIN      
        1 acctataatg aaaagcgaca aaacaactca ttagaaagaa tcatatggaa caattacatt
       61 ttatcacaaa attactagac attaaagacc ctaatatcca gattttagac atcatcaata
      121 aggatacaca caaggaaatc atcgccaaac tggactacga cgcaccatct tgtcctgagt
      181 gcggaaacca attgaaagaa atatgacttt caaaaacctt ctaaaattcc ttatcttgaa
      241 acgactggta tgcctactag aattctcctt agaaagcgtc gattcaagtg ctatcactgt
      301 tcaaaaatga tggttgctga aacttctatc gtcaagaaga atcaccaaat ccctcgtatt
      361 atcaaccaaa aaattgcgca aaagttaatt gaaaagattt ctatgaccga tattgcccat
      421 cagctggcca tttcaacttc aactgtcatt cgaaagctca atgacttcca ctttgagtgt
      481 aattttagaa atctgcctga gattatgtct tgggacgttg aaacagtctg gggagtgact
      541 gtttcaatcg ggagatggag atgagcttca ttgcgcaata ttttaacaat ctcaatatca
      601 tcactgttct tgaaggtaga acacaagctg tcatccgaga tcactttctt aaatatgata
      661 gagccgtccg atgtcgcgtc aaaatcatta cgatggatat gtttagtcct tactatgact
      721 tggctaaaca gcttcgcttt caaatttcta ggctcaggct gaaacagtct cccagactgt
      781 ttcactcccg aatgctaaaa tcgttcttga tcgctttcac attgtacaac atcttagccg
      841 tgctatgagt cgtgtgcgtg ttcaaatcat gaatcagttt catcgaaaat cccatgaata
      901 caaggctatc aagcgctact ggaaactcat tcaacaggat agccgtaaac tgagtgataa
      961 gcgattttat cgtcctactt ttcgtatgca cttaaccaat aaagagattt taaacaagct
     1021 tttgagctat tcagaagact tgaaacacca ctatcagctc ttccagaata aggaaccaga
     1081 gaaatttttc ggacttattg aggacaatct taagcaggtt catcctattt ttcagactgt
     1141 ctttaaaacc tttctaaaga ataaagaaaa aatcgtcaac gctcttcaat taccttattc
     1201 caacgcaaaa ttggaagcga ccaataatct catcaaactt atcaaacgaa acgcctttgg
     1261 ttttcggaac tttgaaaact tcaaaaaaag gatttttatc gctctgaaca tcaaaaaaga
     1321 aaggacgaat tttgtccttt ctcgagctta gccgacttca acccactaca gttgacaaag
     1381 agccgggatt ttttagcttc tttactgaga tggattttcc tttttagttc gtgccaatct
     1441 caaggcacga tttggattga gacgattaaa tagttcttcc aatttctttt cattccaaac
     1501 gtctgcggcg gaaacaaaat taccatccgc atctcggaaa gatatcggtt tatctcccat
     1561 accagtctcc tagtctacaa attcaaactc aaatttacca atgcggacca aatccccatc
     1621 tttagctcca cgcgcacgaa gggcttcatc aacccccata ccacgaagct gacgggcaaa
     1681 tttcatgaca gattcatcac gatcaaagtt ggtcatatta aagagtttca tgagtttttc
     1741 accagaaagt acccatgtcg catcgtcatc acgactaatt tcaaaggctt tttcttcttc
     1801 gtcaaatcca tagtaagctt cttcttccat atcggactcg tcgtagagca aaaattctgg
     1861 tgtcttgtct aacaattcag ctgtagcatc taaaagtgtt gccagacctt gcttggtcaa
     1921 tccagaaatt gggaagatag ctggtaactc ttcaaattca tcataatttt cagacaattt
     1981 tttcttaaat tcttcaagat tttcctgact ctcaggcatg tccatcttat tagctacaat
     2041 aatctgtgga cgctccatga ggcgaagatt gtaagactcc agctctttat tgatagctag
     2101 gtaatcctca tatggatcac ggccttcgct agctgacata tcaatgatgt gaaggataac
     2161 acgtgtacgc tcgatgtgac ggagaaactg agttcccaaa ccaacacctt gactagcccc
     2221 ttcaatcaaa cctggcaagt cggctactgc aaaggattca cctgattggg tgcgaaccat
     2281 acctaaattt ggtacaatag tggtaaagtg gtaggcacca attttaggct tagctgaggt
     2341 aataacactt aaaagtgttg acttccctac agatgggaat cctactaaac cgacatctgc
     2401 caagattttt agttccaatt gtaactcacg ttcctgacct ggttctccat tttcagagat
     2461 ttccggtgca ggattttttg gtgtcgcgaa acgaatattt ccacgtccac cacgaccacc
     2521 gtgggcaacg ataaattctt gcccatgttc aatcaaatct gttaaaacct tgccagtctc
     2581 cgcatcacga acagtcgtac cttgcggtac tcgaactcta aggtcctcag caccacgacc
     2641 atgcatccct ttggtcatcc ctttttcacc agaatcagcc ttgaaatgac gattgtagcg
     2701 gaaatccatc aaggtacgta gtccttcgtc tacaacgaag accacattgc ctccacgacc
     2761 accatcacca ccccaagggc ctccattagg gacatatttt tcacgacgaa aggcaaccat
     2821 accatcgcca ccattaccag ccttgacctt aatcttagct gtatctaaaa acatactcat
     2881 tatttcttct cactttaaaa aagggctggg aaatcccagt cactaaattt tcttgaatct
     2941 attttataga ttactgaggg caccaattgc agttgcaaaa attcccaata aacttgctac
     3001 tagcatgata atcacgataa acaaggttat tttctcaaac atagtttttt tacgatttcc
     3061 attatctcca aatgccattt ttctctcctt cgttacattc tattttctat tatcttagca
     3121 tgaattgagc tagttttcaa tagtcagttg ctactggtgc gataatccat aaaataatgt
     3181 aagctacaat tccagctccg taacagcaag taagaacacc ccaaatgact tgaacgatag
     3241 tcggatccat atccagataa tgggccaccc cagcacaaac acccgcaatc tttttatcac
     3301 gaccgcttct cattaattgt ttttttcata gctgttcctc tttctattct tcatggtctt
     3361 tccaatagtc tctcatactg atcaactgtg tttttgaagc cttcaacatg cgtctagatc
     3421 cttttacagg tacagcaacc acctgttgcg gaagatacaa aactgtctta aagatacgct
     3481 gactgaccgt atcatcttta gccaaatctt tctggaagtt atttgaaata atggcatcca
     3541 gataaaactc atgcactcgt ttcccaaagt tctcagctga aatctcatac aatttctctg
     3601 ataaggtatg ctcgttcatg tctggtgttg caatcagggc ttccaaaata gcaccagcca
     3661 aatcatgttc tccatagtac aaggttccaa acattttatc actgatgagg ttgttcaaat
     3721 aaggatttcc atgagcaatg acaggtgttc cactggctaa gctttccaag taggtcaaac
     3781 cttgcgtttc gcttgtcgat gccgaaatga agaaatccgc cgctttatag taaagagccg
     3841 tctcactagg agcaatcatc cctgtaaaga tgactgagtc ttgaatctct aggttctggg
     3901 cttgctcttt gaggtcattc agataagggc catccccagc tactaccagt ttaatcttgt
     3961 cttcctcttt cagaacatca gcaaaggctg ctaaaactgc ttgaatattt ttttcatagg
     4021 agattctcga aagactaagc aacgtctttt caccatcttg aatccctagt ttactacgca
     4081 gttctttcaa attttcctgc ttgatttccg gacgctcaaa cttggctaat tcaatcccag
     4141 taggaatgac ccgtttttca accttgacct tataatcaga tagcaagtca cggacaatct
     4201 cactaggaca aataacccca tccacatcat gcaggaaacc tctaaccaga tacttgacca
     4261 tactcggccg gatcaacatc cccttagcaa tataatggac atagtcttca tactgggtgt
     4321 gataggtatg gatgactgga attttcaatt cacgcgcaat ccaaatcccc aacaggccaa
     4381 gagaaaattc tgtctgagta tggataatat ctagctgata ctgtttagca atttcaagtg
     4441 ccttgctaaa acctcggtag gcaaagcgac gatccttaaa agcaaagaaa ggaacacttg
     4501 gaatgcggat aatttgccaa tcttcgtagc gattgacatc cttatctgtc gtcgtaaaga
     4561 taaaaacagc atgtccctgc ttttcaagtt ctgttttcaa ggttcgaata ctggtcgcaa
     4621 caccagaaac ctgaggaaaa taggtatctg taaataaacc aattcgcata gattacctca
     4681 ctttttactt tctccctaaa gcggcttgtt tctcataaaa gtccaaccag atttgtaaca
     4741 gatgctcttc agaatactct ctggaaatat tcttagcctt ttctttgaga tcttttaagg
     4801 cagcaggatt tgcttgatat tccaaaatag cctctttcat ctcttctcta cccgctgtcg
     4861 cccgataatt tccctccaaa atcaccttat agagatctaa atcacgcaac ataataggag
     4921 cctcacaact cgcagcttct aaaatagtca taggaaagag ctcattgtaa ctaggcaaca
     4981 agaaaagatc cgctagagca tacaattcgc gcatccgctc tggcgataca atgcctggaa
     5041 aaatcaaatt tttaggggga ttttccataa ttttcttata gtgttcataa ccatctgtca
     5101 taccaccaaa agagaagcca ccagcccaga taaaggtaat ctgaggcaat tcctcagcca
     5161 gacggataaa gtcatcaatc cctttacgtt tctgaacttg cccagcacct actacgataa
     5221 actgattgtc actaagacca agatctgtgc gcagtctaac tacctcttct tgtggtagag
     5281 gatgccattt ttccttgttg acaaagttag gaatataggt cactttttca cgtggaatac
     5341 cagctgctac caaatcctca ataaacatag gattgaccac aaccaagtgc tccatccggt
     5401 tgtaaaaaga aaatacatag cgtttcacaa ttccctttaa gaaaaatgga attttcaaac
     5461 ttccctcaag tgtagctggc aagaaatgca catagccaat ctttctccct gagcgtttct
     5521 tttggaaggt tgataaataa tagggaaaat caatcgtatg aaagtgagtc acatctgcct
     5581 cgattggaag attttctgta acaatcaatt ggtccttggc agcacggtga agaagacgaa
     5641 ctaattcacg gtaagcacct gaaactccct gtcctgctac tttctcactt gaactcaaca
     5701 tattgatgcg taatttcttt ttctccataa ctactattat atcattttct ttgaataaaa
     5761 tcagcaaaag aaaggagaga ctagaggaaa agaggggaaa tttcctcgct tttccaacag
     5821 tctctcacat gcttttatat gtttacttaa tgcctagggc aatgcgggca tagcgactca
     5881 ttttttcaac tgtccaggct ggataccaga ctaatttaac ctcagtatcc gttacttctg
     5941 gaacctctat catagcatca taaatctggt ctgtcaaaag gtctgctaag ggacaaccca
     6001 tagttgtcaa agtcatgtca atctctgttt gccctgtgtc accgtcaaaa cgaatctcat
     6061 agatcaaacc aagattgaca atatcgattc ccaactcagg gtcgatgact tcttccaagg
     6121 ctgttaaaat ccgtgttttg atgttttcaa tttgctcttc tgtataagcc atattttcct
     6181 cactcttagt cttcaataaa atcacgaagc ggtttgctac gacttggttg gcgtagtttt
     6241 ctcaaagcct ttgcttcaat ctgacggata cgctcacgag ttacgttaaa gactttcccc
     6301 acatcttcaa gtgtgcgcat ttttccatca tctagtccaa aacgtagacg cagaacattt
     6361 tcttcacggt ctgtaagagt atctaagatt tcatccaatt gctcacgcaa gacgatacga
     6421 gtcgtataat ccactggatt ttcaatcact tcatcttcga taaagtctcc aaggtggcta
     6481 tcgtcctctt caccgatagg agtttcaaga gatactggtt cttgggcaat cttcaagatt
     6541 tcacgaacct tatcaggtgt catatccatt cgttcagcaa tctgttctgg tgtcggatct
     6601 tgccccaatt cttgaaggag attccgctgt tcacgaacca atttattgat agtttcaacc
     6661 atgtgaactg ggatacggat ggtacgagct tggtctgcaa tagcacgagt gatagcctga
     6721 cgaatccacc aagttgcata agttgaaaac ttgaaccctt tagaatagtc aaacttgtca
     6781 accgccttca tcaagcccat atttccttct tgaatcaagt caaggaactg catgccacga
     6841 ccgacatagc gtttggcaat ggaaacaacc aaacgaagat tggcttccgc aagacgttgt
     6901 ttggcttcga tatcgccagc ttcaacagcc agtgccaact ctttctcctc ttcattggtc
     6961 aagagaggaa cgacccctat ttctttcaag tacatacgga cagggtcatt gaccttagca
     7021 gaagttgacc caatcaagtc ctcatcgctg agttctggtt cttcttcatt gctaagaaca
     7081 cgcgcacttg gatttccttc gttatctgtg atagaaatgc ctgcatcctg aatccgttgc
     7141 aagagatctt caatcccatc agcgtccaag gtaaaaggaa taaccagact tgcattgatt
     7201 tcatcatctg ttgctgtccc tttttgctta tgattacgga taaattctgc tacctgtacg
     7261 tcaaatgttg ttacttcttt ttgttttgtt gccattatta ctccattctt ctcttttggg
     7321 aaattaaacg ttccaattct tctagggctg tatctgtatc tcctacatgg ctagcttcct
     7381 gcaccttctt tttgattctc atattgtcct gattcaagag agccttgttt cgagtcatct
     7441 ctacttcact aagttcctgc ggcgatatct cagcaggcaa atcctgagct aaaacttggt
     7501 accaagctct ttcaacttcc tctgtctgct ctgctaaaac ttctggagga agctttccat
     7561 actggccaag caagtcatat aagacctgaa attcaggtgt agcaaatgca aagtcttctc
     7621 gcaaacggta atcgttcaaa acaagagggg attccatcat ccgatagagt agatgggctt
     7681 ctgccctcat aatagccgat aactgcttgg tgacaggcat ggtgattggc gtcggtctgg
     7741 aaattctttc catgcgattc tgcctttgca cctgacgact ctcattaaca atctgctcaa
     7801 tctgggtata atcaaaggac gccagactgt cagctaaaat atgaatatag ctgttttgag
     7861 cagcgatgga cttttcttga acaatcaagg gagctatttt ttcaataaac tcaatctgag
     7921 cctgcagatt ttcactgttt tcaggtttgt actgatgaat gtagaactca atcggactaa
     7981 tacgagtttt tgttaataga taggccaagt cttctggacc atttttttgt agatactcat
     8041 caggatccaa gttatcaggc atgctaacga tttgcacagg catatcacca atttcatcca
     8101 atgctttcaa tgtcgcggct tgcccagcct tatctccatc gtaaacaaga accaatttct
     8161 tggttaacct tttcagatgc tcaacatgct ctcgactcaa ggccgttccc atcgacgcca
     8221 cagcattttc gattccagcc cgataggctg caataacatc catgaatcct tccatcaggt
     8281 aaatctcact agcttttcca gaagatcttt ttgccctatc catatgatat aattcgtaac
     8341 ttttgttaaa aattgcagtc gatcgactgt ttttatactt agaagtttgt gaatccgttt
     8401 tttgccagat acgacctgag aaggcaatga cctttccttg gtcatttgtc aggggaaaca
     8461 taatgcgatt gtgaaaggtg tctacaaatt gattggcatc cgagagataa aacaggcctg
     8521 aatccagtaa atcctcttca cgatactgat cagacaaacg ttgatagaga tagtttcgtt
     8581 ctggaggtgc taaaccaatc caaaaatgtt taagcacttc atctgtcaaa ccccgctgat
     8641 aaaggtaatt tctggcctct tcgcccatag tcgttgtcat gagaatagca tggtaaaatt
     8701 tggctgcatc ttcgtgcata tcataaagat cttggtgagg tgaggctggc ttctgttcac
     8761 tataaagcgg tttttcaacc tcaatcccga cacgctgacc taagatttgg acagcctcca
     8821 taaaggtaac cccttggtac tcctctatga acttaaagac atcacctgag cgaccacaac
     8881 cgaaacagtg ataaaactgc ttatcctcta caacgttgaa agaaggtgtt ttttcaccat
     8941 gaaaaggaca gagccctaga tagttccgtc ctgccttttg taaagaaatc acatctccta
     9001 tgacttccac aatgttggca ttgtttttga tttcttcaat gacttgtttg tcaaccatac
     9061 acaatacctc catgttatca tagtttactt tatatagtat actttatttc agaaaaaaag
     9121 taaaccattt cactcatttt ccttacttta ttcaaagagt tgataataat cagagatttt
     9181 catttttgct ttttcttctt ggtttaaatc ttggataatc cgtccttctt tcatgacaat
     9241 caagcgattg ccgtatttga gagcatcttc catatgatga gtaatcataa gggctgttag
     9301 ctgatctttc ttaacaaatt catctgtcaa ttccatcaaa gcaacactag tctttggatc
     9361 cagggcagca gtatgctcat ctaacaggag taattcaggt cgcttcaagg ttgccatcaa
     9421 gagactcaaa gcctgtcttt gtccacctga taagaactca atcggtgtat tcaagtgttt
     9481 ctcaagacca tttcctactt tttcaatggt tgcctgaaat tcatccttat agctagtcaa
     9541 gcgtcgtggt aacaatccac gcttttcacc acgaaacttg gcgattaaaa gattttcagc
     9601 gaccgtcata cggggagctg tccccatctt tggatcttgg aagacacgag acaggtactt
     9661 ggcacgcttc tcgggtgaaa acttagtgag ttcttcacct aaaatacgga tagttccact
     9721 agttagtgat aaggtccctg ctatagtgtt aaagagggtt gattttccag caccatttcc
     9781 gcccaaaatc gtgataaagt cccgttcaaa aatttctaag gaaacatcat ttaaaataat
     9841 cttttcttca tcaaagccat ttttaacgat tttggttgca ttttttaatt ctacaattgc
     9901 tgtcatttgc ttaacttggc tcctttcaag attgtttgct taaatgttgg aatcatgagg
     9961 cagactgcta aaatcaaggc actgtataaa cgaaggtaac ttgtattaaa gccaagtgcg
    10021 ataactgccc acactaaaaa ttgataagcg atagaaccta caacgatagt aagcaaacgc
    10081 tctgccaagc tcaaactctt gaaaataact tctccaataa tcaaacttgc aagccccaca
    10141 acgataaccc cgatccctcg agacacatcg gcataacctt cttgctgagc aatgagggca
    10201 cctgcaaggg caatcacacc atttgataag accaagccca tgagctccat gtgtccagta
    10261 tgaatcccga aacttctagc catatcagga ttatcccctg tagcaatata ggcttgtccg
    10321 agtttagtgt ccaagaaaaa gagcatgaga gcaataacaa tactcacaaa gatgagacct
    10381 gtcaagagtt gattcaaatc cgaatcaaaa ggcaaaacat cctgaatttg cttggttcca
    10441 agcaggccta aattcgcacg tcccataatc aagagcatga ttgagtgaca agaagtcatc
    10501 accaaaatcc ctgagagcaa ggttgggatc ttcccttttg tataaagaag gcctgctgcc
    10561 attccagcca aacaacctgc tcctacagca acaagtgtcg ctaaaaatgg gttcacgcct
    10621 ttggttatca aagtgacagc aacagctccc ccaagaggga aggaaccttc tgtcgtcata
    10681 tctggaaagt ttaaaatcct aaatgtcata aagattccca gacctagaat agcccagaca
    10741 aatccttgag aaataatgga aacaatcata ttttatttaa tcctttctat attcatcttt
    10801 ttaaaaaatg ggaagagtct cctcctccct accttattta ttcgatgact tgtcctgctt
    10861 ctttgagaac agactcagga atagtaatac ctagttcttg tgctattttt ttattgatga
    10921 ctgacttacc agttgaaaag acattgactg gggtatcggc tggttttgca cctttcaaga
    10981 cttgcacaat cattttacct gttgccacac caaggtcatg ttggtcaatt acaactgatg
    11041 ccaaaccacc tacttctacc atagctgtcg cactgggata aattggtttc ttagaacttt
    11101 gattgctaga gacaaccgtt ggaaatcctg atgcaatggt gttatcaatt ggaacccaaa
    11161 tagcatctac cttgctagtc ataacagtga cagttgaggc aatttcattt gttgaaggaa
    11221 ctgcaaatgt ttccactgtc agacctgctt tttcagcata agccttaaat tcttcgacct
    11281 gtgtttttga attgtcttcg ctacttgagt aaagagctcc gattgttttc acattcggtg
    11341 tcagagcctt gatgagttca acttgttgtt gagctggatt gtggtcagat acccctgtaa
    11401 cgttgccacc tggttttttc aaatctttaa ccaagttagc accaattggg tctgtaatag
    11461 cggccatgat aaccggtagg tcttttgttg cactagccaa cccttgggct gctggtgttg
    11521 cgataccaac cacaaggtca ttcccatttg caaccaattg tttactcatt gtcgcaacct
    11581 tactttggtc accttctgag ttcataaaat caattttaac ttgatcatct ttatatcctt
    11641 cttctgcaag tccatcttgg atccctttat aaatcaaatc aagggatgga tggctcacaa
    11701 attgaagcac accaatcttg gttattttct tctcatcctt attattctga acttctgatt
    11761 tattcattga agaataaatc aagcttcctg ctactaagac tgctaatgca gcaataattc
    11821 caattaaacg tttatttttc attctgtttc tcctttttat ttcctttaac atatttcact
    11881 tatctaaaca agcgacgcca tcgttttctt tccatactaa cctccatcaa aaaaatcctc
    11941 acacaaaaaa cttgtgtgag gacgtcgatg cgcggtacca cctcaattat agggaatttc
    12001 cctatcgctc agtctcgcaa taacgagatg cactgtaagg tgtgcttacc gaatttttat
    12061 aatttcaaat tctaaatagc attcagccca attttcatca ttgccactta tctgttttca
    12121 gctaccacag actctctaaa aagtttgtat gattactttt ctgaatggtt aaattatatc
    12181 atttttaaac tacttgtcaa tagtctatta gaattttttt gatattcact tttagcattc
    12241 actcttgaaa attatcaacc tgaattacgc aatcctgtcg caattccgtt gatggtgata
    12301 tgaatcaatc gttcttgatc actggacaat tctccacgac gttggcgttt aatcaactct
    12361 aactgaatat agttgagaat attaaagtaa ggcatacggt aatccagact agcttttaga
    12421 tatggattgt cagctaagag ttcgtcatgt ccttcaatag ccaagataac gttcttagta
    12481 acttgccatt catttaaaat agtctcatag atggccttaa cttgctcgtc ttcacaaagt
    12541 ttagcatatt caaaagcaat attcatattt gattttgaca aaaccatatc aacatttgaa
    12601 agaagcgatt ggaagaaagg ccaattttgg tacatatctc gtaagatagc aatattctct
    12661 ggatttttat tgataaattc cttgaagctt gaaccaaccc cgtaccatcc agggaacata
    12721 acacgactct gtgaccatga gaatacccaa gggatggcac gcaaaccacc gatttcagta
    12781 atagtcttac gagcggctgg acgagaacca atattaaaac ttgaaatagc cttgattgga
    12841 cttgactcga agaaataatc atagaaatgc tcattaccaa agaccaaatc acggtagata
    12901 tcgtaactac ggtccactac ttgatccata atggcttcat aacgatttgg ggtattggta
    12961 tcgctcttct tctgagtaat catacggtta atagctgccg atactagcat ttcaaggtta
    13021 tagtaagcgg cgtctttgtt accgtattta ttcccaatta cttcaccctg ctccgtcaag
    13081 cggatacgat ccttaataga cttgagcggt tgagatgtaa tggcttcata ggttggccca
    13141 ccaccacgac cgacagtacc accacgacca tggaagaagg taaccttaac gccaaattca
    13201 tctccaatag cagtcaattg ttgttgagcc ttgtagaggg tccaacatga tgacaagtaa
    13261 ccgccatctt tattactgtc agagtagcca agcatgattt cttggtagtt atttcgtgag
    13321 tcaatccatt ttttggcaag gctaagagaa agatattttc tcattgtttc ctctgaatga
    13381 tccaagtctt caattgtttc aaaaagggga acaatctgaa cacgcgccct ttccgtatcc
    13441 accagtccta cttcttttaa cagaatagct aattctagca tatcagaaag gctggttgca
    13501 tgtgaaatga tggtctgacg gatgacatca tctcccaact tatctttcaa aacacgagcc
    13561 gtcttaaaaa tagctaattc ttttgctaat aattctgatt tttctgcgtg agtcgcagaa
    13621 agaattcggg gatcttcttc taattctttc aagagaaggt cacacttttc ttcttcgctc
    13681 aactcgctat aacgagaatg aattcctgct gatttcaaga gttctgccac acaggcttca
    13741 tagacgctag agtcttgtcg catatcaatt gacgctaagt aaaaaccaaa tatctctact
    13801 gcctgcaata attccacaaa atcacctgaa atcaaggact cgcccttatt ttctagtaga
    13861 gaatctcgaa tggcaatcaa atccttgtag aaatcattgg cggtttcata acgagtccca
    13921 acttcttcat cctcaatcag ataggtttta gttgcctgaa tttttgattg aatatcaaac
    13981 aaggcacgac ggtaaagctc tttttcgcgg taaatcgagt tatccttgga ttgacgagcc
    14041 atttctctga cttgcttgct gacgttgaca atgctagttg aaagagaaaa ttcacgataa
    14101 agttggtaaa tctttttatc atagtagttc atgatgactt cacactgagt gagtgcagac
    14161 tgcttcaagg tctttgctgt aacaaatgga tttccatcac ggtcaccacc tatccacata
    14221 cccatggtga ttggtttagc ctgttttaaa ttcagaccat gcgcttgcgc taagcgctta
    14281 tactccgtcg tcaaatgagg tacagctttc aaaaaggagc tgttataata ttccatagca
    14341 ttcgtgattt cgttagtcac ttttaatttt ttctcacgaa tcatgtctgt ctgcatgata
    14401 atttcgatgt aacgacgcaa atcattgtac catttatctt tattgatcaa ccccaactta
    14461 acatcacggt atttacgcaa aagactatga atatgatttg ttaaatccaa catacttttg
    14521 cgttgcactt gtgttggatg ggctgtcaaa acagggacaa cattcaagtg ttctaggatc
    14581 tcaacggcat tttccttttc tgctaccaat ttaatcgttg tagataattt acctaaatag
    14641 tcctgatcaa tattattttg atgattgatt tcataagcta aatccacatc ctctgaaata
    14701 ttaatcaaaa gaggtaagat agagaaatag cgtgaaatat agaccatttc atcatttgat
    14761 aagctagtca ctagacggtt tagaccttga taatcttcct gcgttgataa ttctttcaac
    14821 tgtattattt tttcaaaggt ctctggggca agcatatttt tagtaatatc ttccagtaat
    14881 tctgttagaa tcaagacttc ttctttcaca acacttttat tactataatt ttctaatttt
    14941 tgaagagaca taaactatcc tttctttatc ctacttcaac agaaggttca ttggttgatt
    15001 ttccaattct cggtacaact tagcgcgttt ttcactggca tcaatattta agacaaaggc
    15061 tactgccact gataagacta gaagactatt tccaccctgg gataagaagg ggaaagtcac
    15121 tcctgtagat ggaatcaagc ccgaaatccc tccgatattg acaaatacct gaaccaacat
    15181 catccctccg acaccgagtg caaccatggc attgaaagga ttctccgctc ggataccgac
    15241 caagataatc cgcaaaatca tgaaaaacaa gagagctaaa ataagactgg caccaacaaa
    15301 gccaaattct tcaatcacga tagaaaagac aaagtctgta tgagcttctg gcaaataacc
    15361 tcgtttttca atcgagtttc caagacctag accaaaccaa ctgccattga ccatggcaaa
    15421 ataagaatta gctaactggt gacctgcatc agcacgatcg gcaaaaggat taaaaaaggc
    15481 actaaagcgc ttggctacat agccaaatac tggaattttt gaaaaggtct caacaccgat
    15541 taggctgata gtggtcaaga caaagacaga agcggcagat acgagcgcca gaatggttga
    15601 aaaccagcga taagcgattc cactaactgt atacataatc aaggaaacca agactaaaat
    15661 agtcgcattt cctaaatcag ggaaaattcc caaacttcca atcagaacta ggagaacgaa
    15721 tcgccaatca ttaaaagcac ggggaagcca ttgattttga gtcaaaactt gaaaatcata
    15781 agtagctatt tcttcttgct gtttggagaa tcggtgagct aaataccaaa taataatgat
    15841 ttttaagtac tcagctggct gaatagttac tcctgcaacc gaaatccaac cgtatgcccc
    15901 gtttacggaa ataccaataa aacgagccaa gaacaataaa agcatttcta ttaatataac
    15961 taaaatgatt agtcgctcat ttctcaaaaa atctagtctc aatttataaa ttaaggcaat
    16021 cagtatcaaa ctaacaatcc aaaagattcc ttggtttcga accaactgca aggcactctt
    16081 gccttcttca attaaaatag cactggtggt cgaatagacc acaatcaagc ccaaaataga
    16141 taaaagcaag tagggaatca agatggaata atttaataag tgcctcttac taatcttcat
    16201 agcatcacca ctctactagg atacagataa atctgttcca aattccgttt tattttctag
    16261 ttttgattgc tattatacca ttttttcaga aagaaaaaaa ctcttacctt acaatccttc
    16321 gaattttact gtttttacag aattaaggca gaatttgaaa tcgtaaaacc attttgaata
    16381 agagttgctt caacccattg actccgacgg attaagttgc tttcgtgaat gccaaaatca
    16441 gccgcaattt gttcataagt gcgctattct cgcatgtatt gaatagttac cataaggaga
    16501 tcgtctagga ttaatttgct ttttcgtcca ccttttgcgc gtttacgttg ataagctgtt
    16561 tttaacacag ctaacatctc ttcaaaagtc gtgcgctgaa cacctacaag gatcttgaaa
    16621 cggctatcgc ttaattgttt acttgcttca tcatccatag ttttattgta ttgtattttt
    16681 gtttcgcagg aagtctatta ttcctttcgt tccaaggttt ttacgctttt agcaacaagc
    16741 ttacacactg agcgtttcgg acttaccata tcatttcgtt ggagatttta tcatcaattt
    16801 ttagattaaa aaaaatttcc caatcttcac aaacttctgt agcaggaatt gtatgaatct
    16861 ttctaagtat ctttcctgct tctacaccat atgtgtattg ttggttttct gaataagcta
    16921 aaatgctatc tattgcatct cttccgtcta tccattcgtg taaagaatgt acttcgtcat
    16981 cgcagagttc aatgctaatt ggtttacaca tcggaactcc aagagaagct actttctcca
    17041 tcatatcaaa ttcaaatttt tttataatct aacttcgact tatcagaaac acgcaagaaa
    17101 tatttttact gattttgatc tgtcacacaa tattttttat catctgacca gcctttattt
    17161 atggctatct tactactaaa atccatcaag cacactccga ttcactttac aacacttttt
    17221 gcagttttca ctagtaacct atccagttcg tctacacttt tatttcctag atccattttt
    17281 acattatgaa agttaatcaa ttttctctat gatgtttcca agtttatcca atacaagaca
    17341 agaatgatca tttagtggaa ttatgggaac attaacgagt tcttcagctc tatccttatt
    17401 tgctttatca ttccaggaat cataatggac actaattaaa aactgactaa agagtcctaa
    17461 tccatttttt atctttatct gatgatctga attatcatta ggtgagacat agactttttc
    17521 tcctaatagt agggctcctg cagaaaatcc tataattttt gcctctttat taagcatatg
    17581 atcgatataa cttttgaact cctgattaac ataagtagca atatattttt ccgtatttcc
    17641 accaccgatg ataattatgt cagcatctag atagctatca agatcaatct gctcagtgtc
    17701 caggagcaag taatcaatgt ttagattagg aaattgactt tgaaaaactt ccgtgtactt
    17761 tttcatgtac ggttcccaat tttctcgaaa aactgtaaaa atgataattc ttttaatctt
    17821 ggttgataat acaattttat caacaatact atatttcttc attgggggat tcccacccat
    17881 caaaaaaatt tgttctttca agttaacaca ctttctaaag atacataaag tttaaacaag
    17941 tttattcacg tttctaaatt ataatttttt cttaaaatga ataattctat ttgcctcctg
    18001 aaatccaata ttgagatgaa atcttataga atccgtattc gttaaagtac agtcacttgc
    18061 aaattcctta catcctttat ttttcgccca ttcctcacat tttgtacaga gatttttagc
    18121 aatatccttt aaacgatatt cctcgtcaac aataatccct tctaagaatc caacaggact
    18181 atatttacaa ccttcaacat aatcaaatct gagtgaacat agtgctagac ctacaattgt
    18241 gtcaccttca acttcagtaa agattgcagt atttttgcca ttcgtatatt tttttacttc
    18301 atcaatagct tctttatcgg tcaattgggg ccataattgt ttcattagtt tagccgtttt
    18361 tataaaatct tttgttattc catccatatt gatgttcctc cgcaaattac aagtaaatgt
    18421 ttcgaatcat gctgatactt tgttactcat tgattgatac caataccatc cccttctact
    18481 tttcgactgt ctcagatcgg aagagcagag ccacgcactc agcggttcgg acttacctta
    18541 tcatttcgtc ggttttcctc ctcattctac gagtcctacc gcatgggaga tcatttactt
    18601 ctacttcgct gatgcctcag cttgtacaag cagtgatact gcctcaacat ggtgcgtcgt
    18661 agtccagttt ggcgatgatt tccttgtgtg tatccttatt gatgatatct agaatcttga
    18721 tgtttgggtc tttaatatcg agcagttttg tgataaaatg taattgttcc atatgattct
    18781 ttctaatgag ttgttttgtc gcttttcatt ataggtcata tgggactttt tttctacaca
    18841 aaataggctc cataatatcc ataggggatt tacccactac aaatattata gagcctgaaa
    18901 aattctatat gtccatctgg tattggacta aagttatttc ctctaggata atactcatta
    18961 tattgaatat cataacgccc agttgtagac cctcgtggag cagcaccaat tccagtatct
    19021 ccactatcaa gaaaaatctc tacttcaatt gttgcgaacc cttttgagtc aaagatatat
    19081 ctgcaaatac cattaattat tttcataggc ttccactttc ttttttatca ttgaaaatta
    19141 cttttttata aatgtcgtcg attttatttt ctattgagat ctaatttccc tactcagctc
    19201 aataatacgt tcacataggt ttgggaaatc tataccagct gctttcgctt cctgtggtaa
    19261 taaacttgtt ttagtcatac ctggtaaact atttgattca ataaaatata catccccctt
    19321 ctcatctaca ataaaatcag tacgtgaata aacattaaat ccaagagcct tatgtatttt
    19381 atatgcggat ttttgtaagg tatgagttaa cttttcagat atttttgcgg gaacgacttc
    19441 ttcagctgca ccaacagtgt acttgttatt ataatcataa aaaccatttt ttacttttat
    19501 ttcaataacc ggtaaaacag tttcacctaa aatacctacc gaaaattctc tccccttaat
    19561 atacttttct acaaataatg aaccaagttc aggatgctct ttataataaa tgtcaaattg
    19621 ttttttattt tgaaatatct taataccttt acttgaacca cttctaattg gctttataac
    19681 aataggaaaa tcatttgcct gaattctatc aaccatcaag ttcgaagcac attttattcc
    19741 aacagaacta gccactattt ttgataattt tttatccatg ctaatagctg tactaagaaa
    19801 cgaatttcct gtatagtcta ttttttctac atcaaaaata gcctgtagtt tcccattctc
    19861 acctattcca ccatgagttg ctaagaaaac tatatcaacc tttctacaaa catcaataat
    19921 acccgaacca atctcaactt tttgttcatt taatccgcgc tcactttttt caatttctcc
    19981 tatctcgtac gaacagtctt gagataaatc tatagaaatc acatcatacc ccaatgttaa
    20041 tagactttta ctaatctcct ttgcagaatt ttctgacacc tctctctctt cgctaaggcc
    20101 accatatagt acaacaattt ttttaataat agccattcac ttaacctcct tattagaatc
    20161 tta
//
LOCUS       DAVKMO010000035        20085 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVKMO010000035 DAVKMO010000000
VERSION     DAVKMO010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.035"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            168..3269
                     /locus_tag="VW361_001416"
     CDS             168..3269
                     /locus_tag="VW361_001416"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU9744440.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDISLKLPRFNPARPAVEELRERAELGFVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKSEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            3352..4359
                     /gene="pfkA"
                     /locus_tag="VW361_001417"
     CDS             3352..4359
                     /gene="pfkA"
                     /locus_tag="VW361_001417"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU9744441.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGATSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            4418..5923
                     /gene="pyk"
                     /locus_tag="VW361_001418"
     CDS             4418..5923
                     /gene="pyk"
                     /locus_tag="VW361_001418"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU9744442.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6607..6832)
                     /locus_tag="VW361_001419"
                     /pseudo
     CDS             complement(6607..6832)
                     /locus_tag="VW361_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7680..8552
                     /locus_tag="VW361_001420"
     CDS             7680..8552
                     /locus_tag="VW361_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU9744443.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(8698..9042)
                     /locus_tag="VW361_001421"
                     /pseudo
     CDS             complement(8698..9042)
                     /locus_tag="VW361_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9185..9496
                     /locus_tag="VW361_001422"
     CDS             9185..9496
                     /locus_tag="VW361_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744444.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNVSDKETAEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9500..10216
                     /locus_tag="VW361_001423"
     CDS             9500..10216
                     /locus_tag="VW361_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9744445.1"
                     /translation="MKKYFIGCLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYLASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(10346..11161)
                     /locus_tag="VW361_001424"
     CDS             complement(10346..11161)
                     /locus_tag="VW361_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU9744446.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(11158..12063)
                     /locus_tag="VW361_001425"
     CDS             complement(11158..12063)
                     /locus_tag="VW361_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU9744447.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIISGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            12520..14649
                     /locus_tag="VW361_001426"
     CDS             12520..14649
                     /locus_tag="VW361_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU9744448.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            14636..15085
                     /locus_tag="VW361_001427"
     CDS             14636..15085
                     /locus_tag="VW361_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU9744449.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            15144..15416
                     /locus_tag="VW361_001428"
     CDS             15144..15416
                     /locus_tag="VW361_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9744450.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(15770..15961)
                     /locus_tag="VW361_001429"
     CDS             complement(15770..15961)
                     /locus_tag="VW361_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744451.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            16389..17147
                     /locus_tag="VW361_001430"
     CDS             16389..17147
                     /locus_tag="VW361_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744452.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            17149..19137
                     /locus_tag="VW361_001431"
     CDS             17149..19137
                     /locus_tag="VW361_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9744453.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(19179..19823)
                     /locus_tag="VW361_001432"
     CDS             complement(19179..19823)
                     /locus_tag="VW361_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU9744454.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSEYR
                     IPATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(19795..>20085)
                     /locus_tag="VW361_001433"
     CDS             complement(19795..>20085)
                     /locus_tag="VW361_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9744455.1"
                     /translation="YYAHPYASWERGTNENHNRLIHRWLPKGTKKMTPKEVAFIEKWI
                     NNYPKKCLNYKSPREDFLMANLNLKFSVRNKSRNRFKFCRSFKYPARRCSWC"
BASE COUNT         6172 a         3646 c         4229 g         6038 t
ORIGIN      
        1 tatatgcttt ctatttttat atacaatata gtataaatat aaaaatgatg acaaaaatac
       61 aaatgaatag aaaataaatt agtaagctga tgaaattttt ctcaagagaa gccatttata
      121 ggtgaaaatg gtataatata gtgagaagga tagaggagaa gtgtaaattg atcgcacaac
      181 tagatacaaa aacagtctat agttttatgg aaagcgtcat ttcgatcgaa aagtatgtga
      241 gagcagctaa agaatacggc tacactcatt tggctatgat ggatattgac aatctttatg
      301 gcgctttcga ctttctagag attacaaaaa aatacggcat tcatcctttg ctagggcttg
      361 aaatgacagt gtttgtagat gatcaggaag tgaatttgcg ctttttagct ctatctagtg
      421 tgggctatca gcagttgatg aagctttcga cagccaagat gcagggggag aaaacttggt
      481 cagtcctgtc ccagtacctg gaggatatcg cggtcattgt gccttatttt gatagagttg
      541 agtcgttaga actaggctgt gattactata taggggttta tccagaaaca ctagcaagcg
      601 aatttcatca tcctatctta cctctttatc gggtcaacgc ttttgaaagc agggatagag
      661 aagttcttca agttttaaca gcgattaaag aaaatctacc gctcagagaa gttcccttgc
      721 gttcgagaca agatgtcttt atatcagcaa gttctttaga gaaactattc caagagcgtt
      781 ttccgcaagc tttggacaat ttagaaaagc ttatttcagg catttcttac gacttggata
      841 ttagtctgaa actgcctcgt tttaatccag ctagaccagc agtagaggag ttgagagagc
      901 gtgctgaact ggggtttgtt cagaaggggt tgactagtaa agaatatcaa gatagactag
      961 accaagaatt gtctgttatt catgatatgg gctttgatga ttatttcttg gttgtttggg
     1021 atttgttgcg ttttggacga tcgaatggct attatatggg aatgggaagg ggttctgcag
     1081 taggcagttt ggtttcttat gccttagaca tcacggggat tgacccagta gagaaaaatc
     1141 tgatttttga acgctttctt aatcgtgaac gctataccat gcctgatatt gatattgata
     1201 tcccagatat ttatcgtcca gattttatca gatatgttgg taataaatat ggtagtaaac
     1261 atgcggcaca aatcgttact ttttcaacct ttggagccaa gcaagctctt cgagatgtct
     1321 tgaaacgctt tggtgtgcca gagtatgaat tatctgcaat tactaagaaa atcagttttc
     1381 gtgacaatct taagtcggcc tatgagggca atctccagtt tcgtcagcaa atcaatagta
     1441 agttagaata ccaaaaagct tttgagattg cttgcaagat agagggctat ccaaggcaaa
     1501 cctctgtcca tgcggctggt gttgtaatta gtgaccaaga tttaaccaac tacattcctc
     1561 taaagtatgg tgatgaaatt ccactgactc agtatgatgc tcatggagtt gaggctagcg
     1621 gacttttgaa gatggacttt ctgggactac gaaatttgac ctttgtccag aagatgcaag
     1681 agttgcttgc tgaaacagaa ggtattcacc ttaaaattga agaaatagat ttggaagaca
     1741 aagaaacgtt agatttattt gcctctggaa atacaaaagg tatctttcaa tttgagcaac
     1801 ctggtgccat tcgcttgctc aaacgtgttc aaccagtctg ttttgaagat gtcgtagcaa
     1861 ctacttctct aaatcgacca ggtgcaagtg actacatcaa taattttgtg gcaaggaagc
     1921 atgggcagga agaagtgact gttctagatt cagctctgga ggatattttg gctccaactt
     1981 atggcattat gctctatcag gagcaggtta tgcaggttgc tcagcgattt gctggattta
     2041 gtcttgggaa ggccgatatt ttgcgtcgag ctatgggtaa aaaggatgcc tctgctatgc
     2101 atgagatgag ggcttccttt attcaaggct ccatagaagc aggccatact gcggaaaaat
     2161 cagagcaggt ttttgatgtt atggagaagt ttgcaggtta tggatttaat agatctcatg
     2221 cctacgccta ctcagccttg gccttccagt tggcttattt caaaacgcat tatccagcca
     2281 ttttttatca ggtcatgtta aattattcca acagtgatta cttaatagat gcacttgaag
     2341 caggttttga agtagcctct ctatccatca atactattcc ctatcacgat aaaattgcca
     2401 acaagtctat ctatataggt ttgaaatcga ttaaggggct cagcaaggac ttggcgcttt
     2461 ggattattga acatagacct tattctaaca ttgaagattt tatagctaaa ttacctgaga
     2521 attatctgaa acttcctctg ctagaacctt tggtaaaagt tggtcttttc gattcatttg
     2581 aaaaaaatcg tcaaaaagta tttaataact tagctaatct atttgaattt gtgaaagagt
     2641 tgggaagttt gtttggagat gctatttata gttggcagga atcggaagat tggacggaac
     2701 aagaaaaatt ttatatggaa caagagcttt tagggatagg tgtcagcaaa catccactac
     2761 aagctattgc aagtaaggct atttacccga ttaccccaat cggaaatttg tcagaaaata
     2821 gctatgctat tattttggtt gaagttcaga aaataaaagt gattcgtacc aaaaagggtg
     2881 aaaatatggc cttcttacag gcagatgata gtaagaaaaa attggatgtc actctctttt
     2941 cagacttata tcgtcaggtt ggacaggaaa taaaagaggg agccttctac tatgtaaaag
     3001 gaaaaataca atcacgtgat ggccgtttgc aaatgattgc acaagaaata agagaagcag
     3061 ttgctgaacg cttttggata caggtgaaaa atcatgaatc ggatcaagaa atttcacgta
     3121 ttttagaaca atttaaaggc ccaatcccag tcatcatccg gtatgaagag gaacagaaaa
     3181 ccatcgtttc tccccatcat tttgtagcta aatccaatga attagaggag aaattgaatg
     3241 aaatcgttat gaaaacgatt tatcgctaaa aatacggaaa atagaagaat tttaaaatca
     3301 aatgtgatat aatcaagaag aatgttaaaa gaaaaaggag cataaaccaa tatgaaacgt
     3361 attgctgttt tgactagtgg cggagacgca cctggtatga acgctgctat ccgtgcagtt
     3421 gttcgtcaag caatttcaga aggaatggaa gtgtttggta tctatgacgg atatgctggt
     3481 atggttgccg gtgaaattca tcccctagat gcagcttcag taggagacat catttctcgt
     3541 ggtggtactt ttcttcactc agctcgttac ccagagttcg ctcaacttga agggcaactt
     3601 aaagggattg agcaattgaa aaaacacgga attgaaggtg tagttgttat cggtggtgac
     3661 ggatcttacc acggcgctat gcgtttgact gaacatggct tcccagctat tggtcttcca
     3721 ggtacaatcg ataacgatat cgttggtact gactttacaa tcggttttga cacagcggtt
     3781 actactgcca tggacgctat cgataagatt cgtgatacat catcaagtca ccgtcgtact
     3841 tttgtaatcg aagttatggg acgtaacgct ggtgatatcg ctctttgggc tggtattgca
     3901 actggtgctg atgaaatcat catccctgaa gcaggcttca agatggaaga tatcgtagca
     3961 agcatcaaag ctggttatga atgtggtaaa aaacacaata tcatcgtctt agctgaaggt
     4021 gtgatgtcag cggctgaatt tggtcaaaaa cttaaagaag ctggagctac aagcgacctt
     4081 cgtgtaacag aacttggaca tattcaacgt ggtggttctc caactgcgcg tgaccgtgtt
     4141 ttggcgtcac gtatgggtgc acatgctgtt aaacttctta aagaaggtat cggtggtgtt
     4201 gcggttggta ttcgtaacga aaaaatggtt gaaaatccaa ttcttggtac tgcagaagaa
     4261 ggggcattgt ttagccttac tgcagaaggt aagattgtgg ttaacaaccc acacaaagcc
     4321 gatattgagc tatctagctt gaataagagc ttgtcataat ttacaattta gttaataaga
     4381 ccaaaaaggt catatatata aaggagtcac aaaaatcatg aacaaacgtg taaaaatcgt
     4441 tgcaactttg ggtcctgcgg tagaaatccg tggtggtaaa aaattcggtg aggacggata
     4501 ctggggtgaa aaacttgatg ttgaagcttc agctaaaaac attgctaaat tgattgaagc
     4561 tggtgctaac acattccgat tcaacttctc acacggcgac caccaagaac aaggtgagcg
     4621 tatggcaact gttaaacttg cggaaaaaat tgcaggtaaa aaagttggtt tccttcttga
     4681 tacaaaagga cctgaaatcc gtacagaatt gttcgaaggt gaagctaaag aatattcata
     4741 caaaactggt gaaaaaattc gtgttgcaac taaacaagga atcaaatcaa ctcgtgaagt
     4801 gattgcgttg aacgttgctg gtgctcttga tatctatgat gatgttgaag ttggtcgtca
     4861 agttttggtt gacgatggta aacttggtct tcgtgtggtt gctaaagatg atgcaactcg
     4921 tgaatttgaa gttgaagttg aaaacgatgg tatcatcgct aaacaaaaag gtgtgaacat
     4981 ccctaacact aaaattcctt tcccagctct tgctgaacgc gataacgacg atatccgttt
     5041 cggtcttgaa caaggtatca acttcatcgc aatttcattc gtacgtactg caaaagatgt
     5101 gaacgaagtt cgtgcaatct gtgaagaaac tggaaacgga catgttcaat tgttcgctaa
     5161 aatcgaaaac caacaaggta tcgataactt agatgaaatc atcgaagcag ctgatggtat
     5221 tatgattgct cgtggtgata tgggtatcga agtaccgttc gaaatggttc cagtttatca
     5281 aaaaatgatt atcaagaaag tcaatgctgc aggtaaagtt gttatcactg caacaaacat
     5341 gcttgaaaca atgactgaaa aaccacgtgc aactcgttca gaagtatcag acgtattcaa
     5401 cgctgttatc gacggaactg acgctacaat gttgtcaggc gagtctgcaa acggtaaata
     5461 cccactcgag tcagtaacta caatggctac aatcgacaag aacgctcaag ctcttcttaa
     5521 tgaatacgga cgtcttgatt cagattcatt tgagcgtaac tctaagacag aagtaatggc
     5581 ttctgctgtt aaagatgcta ctagctcaat ggatatcaaa ttggttgtaa ctcttactaa
     5641 gacaggtcat actgcacgtt tgatttctaa ataccgtcca aatgctgaca tcttagcatt
     5701 gacatttgac gaattgacag aacgtggctt gatgttgaac tggggtgtta tcccaatgtt
     5761 gacagatgct ccatcttcaa ctgacgatat gttcgaaatc gctgaacgta aagcggtaga
     5821 agcaggtctc gttgagtcag gcgatgatat cgttatcgtt gctggtgtgc cagtaggaga
     5881 agctgttcgc acaaacacaa tgcgtatccg cacagtacgt taagaaaaat ataaaaacct
     5941 atcatatcca gctttagagc ttgtgtgata ggctttttgt atagagggta agaaataggc
     6001 aaaactttca taatggattg atactcttcg aaaatctctt caaaccacgt cagcgtcgcc
     6061 ttaccgtact caagtacagc ttgcggctag cttcctagtt tgctctttga ttttcattga
     6121 gtatgaaata agatatgcat aaattgatta gaaagtcaaa tgaatttcta caaatgtttt
     6181 agcaatcgca atctacttgt ctagattcga tctgatatat tttcgattta atgatatggt
     6241 atttaaaacc tccaaagtag cttgctccat tcttttacct acgtgagtct agatgttatt
     6301 tactgtttta gcgtttttgt gttctactct aaccattata gcattcttct cagctagtgt
     6361 actaaggagt gtgtgcctga aaatatggga actaaggggc tggtttatcg gtttctctag
     6421 tttagtattt gccttttgca aagtgatctt aaatgccttt ctctaaattt acatatcact
     6481 attgtttaac aaaatctaat ctattttagg tcacttattc tttttttgaa atgtagaata
     6541 aactttttca aagtttttcg aatcttttaa aatctgtttg ttttatatcg ccattctccc
     6601 ccttttttaa ttctccctat atagcctgac aactttcccg atggtacgaa tatggttgct
     6661 ttcgtctagg tggatgtcgg agtattcggg attgagtttt tttgaggtag ccttggcgga
     6721 gtttcttgac atagttagtg ccgtctactt ggaagatgcc gatggtatta tagtcaatct
     6781 gtggggtatt cttgataaat aggtagtcgc tgtttcttat ctttggctcc atggacttgc
     6841 tgacgacata agcgattggg tcgtagtcgt ctgggataat ggaaactcca tatctaaatc
     6901 gttgtcctgc atcgagcggc tacctgcaga gataaactac ctaacacgag agtaagtagt
     6961 ctgtctgtag tcgtccagtc tgatgatttt tacgatactt cgtttttctg atcatacagt
     7021 tgcctctcgg cataggtcag aactttacct tgtctgggtg gttcccgttg gtcgtagata
     7081 gattggatat cgctaggaga atccttttga actggaggaa agagggcatc gatcaagcta
     7141 ctgaatactt taactaagtc aaatatagta tttttcttag tagacctaac ccttttttca
     7201 taatttctaa tggtgttttt acttatacct atcttagtac ccaattctta ttgagtccaa
     7261 ccattactag tctatattgt tttatagttg attgagtttg gaatagtacg ctgtagctgc
     7321 taaaacattt ctagaaatta atttgacttt cctaatagag ttgttcatat cttatttcaa
     7381 tctattatgt ttttcacctc taacaatcgc aatctcttct ttatccatga atgaaatcgc
     7441 tttctatttt tgtaagtaaa gcataacacg aaatccacga aaatgaaaac ctttgttgtg
     7501 ttttcgtaaa aaatttgttg acagagcacg aaacgcctac tataattaaa tcaagcttaa
     7561 ggaaataaca aaaaaacaaa tcggagggaa agacgatgaa cacattaaat gagaaagtaa
     7621 tcaatatctg taaagcaata gttaaagaaa ctttaatcca agacatttag gagaaagaaa
     7681 tgaagaaatc aagaaaatta gccacattag gaatctgttc agccttgttt ttaggcttgg
     7741 ctgcttgtca acaacaacat gctacttctg aggggacgaa tcaaaggcaa agcagttcag
     7801 cgaaagttcc atggaaagct tcatacacca acctaaacaa ccaggtaagt acagaagagg
     7861 tcaaatctct cttatcagct cacttggatc caaatagtgt tgatgcattt tttaatctcg
     7921 ttaatgacta taataccatt gtcggctcaa ctggcttatc aggagatttc acttccttta
     7981 ctcacaccga atacgatgtt gagaaaatca gtcatctctg gaatcaaaag aagggcgatt
     8041 tcgttgggac caactgccgt atcaatagtt attgtctttt gaaaaattca gtcaccattc
     8101 caaagcttga aaagaatgac caattgcttt tcctagataa tgatgcgatt gataaaggaa
     8161 aggtctttga ttcacaagat aaggaagagt ttgatattct attttcgaga gttccaactg
     8221 aggcaactac agatgtcaag gttcacgctg aaaagatgga aacattcttc tcacaatttc
     8281 aattcaatga aaaagctcga atgctgtctg tagtcttgca cgacaatttg gatggcgagt
     8341 atctgtttgt aggccacgtt ggggtcttag tacctgctga tgacggtttc ttatttgtag
     8401 agaaattgac tttcgaagag ccctaccaag cgattaaatt tgctagtaag gaagattgct
     8461 acaagtattt gggcaccaag tatgcggatt atacaggcga gggactggct aagcctttta
     8521 tcatggataa tgataagtgg gttaaacttt aatagtgtta tgatatgaca gtaatcttag
     8581 gatttttatt tctatttttg atgagttggt gggttatttc aatcgttaat agccagaaac
     8641 cacgcaaaaa tgaaacattt attggctata tccaaagata cgatattgat gggaatggct
     8701 atcaatcatt accgtgtcct cagaactgag aggagttctt gaaaccgtaa aaccgctttg
     8761 aacaagagtt acttcaaccc attggctccg acggagtaag ttgctttcgt gaataccaaa
     8821 atcagccgca atttgttcat aagttcgata ttctcgcaca tattgaagag tggccataag
     8881 aaggtcttct aggcttaatt taggttttcg tccacctttt gcgtgtttaa gttgataagc
     8941 tgtttttaat acagctaaca tctcttcaaa agtggtacgc tgaacaccaa caagacattt
     9001 aaatcgtgca tcagttagtt gtttacttgc ttcataattc atagaactac tataccatat
     9061 tttgtttcgc aggaagtcta atgctaaaat cttatcagtg agaagatttc ttaaagttta
     9121 ttctttgtag tttcatctgt attagtacat aatttaactt agagaaaata ggaggactaa
     9181 tcgaatggaa ttaaaagatt ttacagaaaa agaacaggaa atgattaaga aaaggcttac
     9241 aatgtctaat gttagtgaca aagaaactgc tgagaagatt ctggcgctag taccacaaga
     9301 cttgattaag cgaatcccgt tttttgtcag aaaacatgct acaacacgta cgattaaacg
     9361 catttcaatt gaacaccctg aactctacgc tgtagctcaa acaagtggtg agattccaga
     9421 aaaagaacgc gaagaattgc gtcagattat cacaactatc tttgaacaaa agatgaataa
     9481 gcatagtatt aagtagagaa tgaaaaaata ttttattggc tgtttgggaa gcaatgccta
     9541 tcatagcaag gattttcttc aagaactaga ttcgcaggtc tattttctaa atccatatga
     9601 aaagcatctt cgagatgaaa cagaattgaa atcatggttt aaaaatgaga ttgtagagga
     9661 agaatctatt tgtctgatag gtcattctct tggaggagat ttagctcgtt atctcgcatc
     9721 ggaatttgaa gaagtaaaga aactgattct tttggatggt ggctatctag atttagataa
     9781 gattttacct ttggatacag agttagagga aactaaaaat tatatcaaat ctcaaattat
     9841 ttcggactta gatgttctta cttctaaaga aaaatctgaa gcaaagcatt ggtcagaaaa
     9901 tatggagaaa gctgtaagac agtcttatca ctggaatgtt gagtataata gatatgagtt
     9961 ggctataaat tatgaaaata tagaagcgat actccgccta cggagaaaaa tacaagcttt
    10021 taagagagaa gtgggagata ccttgtttat tagtcctcgc tatcctaatg aagctacatg
    10081 gagagaggaa gccctaaaag aattgccaga ctattttgat actatttttt tagaaaactt
    10141 tggccatgag ctttatactc aagcacctaa agaaatcgct agtctaatga atgagtggct
    10201 cgcttatttt ctatgagcta cttgtattgc tggaaatggt ataagatgaa aatctacaag
    10261 tcactaattt tcatataaca aaaaaacgaa caggctcttt ttctgttatt cagaagagaa
    10321 cttgttcgtt tttatcttga ttttcttaaa aagctctata tacataggga ttttctggtt
    10381 tatcgacttt ggtaaagctg tcgatttcca aggttggaag gttttgtttg agttctttat
    10441 ggtagtgatt gaccagtttt cctttggctg taatccaggt gttgttttca tactgccggg
    10501 tattgccctt ggtcagcaat ccatagacac cagaatctgc gatacagtgg ataatgccga
    10561 atcggaacag aaattgacta ttggcatgac tggggtcgtt atagacaaag cctgtaaact
    10621 ggattgtctt gccctcaaat tcatctggat agtcgtagat agcctccatg acttccatat
    10681 agttttcatt agtgatctga atactatctt gggataagta tttatccgcc gccgttcgca
    10741 tttccttttc ataggctgat tttgaaaaat aagaactagt atctggtttc aaatattggc
    10801 ttgtagtccc ttcacttgtc tgaatagcta gatccgttcc ttccgatagg gggaaatgat
    10861 aacctttagc agaaacggtc tgagaatcca agctaacagt tgggaaagtt aagccgatga
    10921 caagtggaat agccagaaga gaaatactcg tcatcttggc caatcggctg ttcagatgac
    10981 tgtgggtttt gacttgcttc atccagatat acaattgaac aattgccaag ataaaggaaa
    11041 gcaccatgga gatataggcc agataggaat agtgcatgtt gatgtactgg tttagtttgc
    11101 ccgacagatg gaggtaaata gtcagttcaa aatagccagc taaaactaaa aatcgaatca
    11161 taggatgact ccaatcaaga gagaatagac taagacgaca agagttacaa ttgttatgaa
    11221 gtgactgata aatcgtgctt tcaagtaatt tttcatcatg agaatatttt tgatatccag
    11281 cattggacca atgacgagaa aggccagaac tggtgccaaa ccgaaactcg agagaagaga
    11341 agcacctata aaggcatccg cctcactaca gagcgaaaga agaaaggcta aaatcatcaa
    11401 gagcaggatg gcaaaaagag gggtcgcact gatagaggtc agaatccgag tcggaacgta
    11461 gacctgtatt atagaagcaa agaggcagcc aaataccaaa taacgccccg tatcaaaaaa
    11521 ttcatcaatg gcctgcacaa agacttgaaa aacttttttt gcagaactca agtaagaaaa
    11581 atcatgctca tgacaagcca gacgattttc tttctgaatc ggttcttgcc agaaaaatcc
    11641 tagaaaaatt cctagtatta cagccacaag aatggaaccc agagctcgta atagggcgac
    11701 atggaaggag ttgccaaagg cagaataggt cgcaaaaaga acaatgggat tgataacagg
    11761 tgctgtcaca agaaaaggaa cggccgtgta acttggaacc tttttttcca gaaaacgatt
    11821 gatgatgggg acgattccac attcacaaga agggaaaaac ataccgacga aggtcccaaa
    11881 aaagattctc ccccaacgat ttcgagggag aaaatgataa accttgtcag gtgtgatata
    11941 aacttcaatc agccctgaga taatgcttcc tatcagaacg aagggaaggg cttcaatgat
    12001 aatggagaga aaaatggctc cagtttgaag tacactagat gggagttgtt gaaaagcagt
    12061 catctagttt ttcttttctg ctttgacttt tttctctttg tcatcaggga aagtaacttg
    12121 tttcaaatca gggagtttag caaactcttc aaacatcttg tccaagtcgt ctcgttttgt
    12181 aaattttaca gccataggtg tacctcgatt ctaaattcta cctctattat actattattt
    12241 tgcggaaaag ggagtttttt aatttgtttt cgatagttga tactcttcga aaatctcttc
    12301 aaaccacgtc agcttcgcct taccgtagta cggttactga cttcgtcagt tctatccaca
    12361 acctcaaaac agtgttttga gctgacttcg tcagtcttat ccacaacctc aaaacagtat
    12421 tttgagcagc ctacggctag cttcctagtt tgctttttga tttttattga gtatgaaaag
    12481 gattggagaa agccttccag cttgtggtat aatagattta tggataaaaa atatgaaaaa
    12541 atctctcagg atttgggagt gacgttaaag caaattgata ccgttctaag tttgacagct
    12601 gaaggggcga ctattccctt tatcgcgcgt tatcgcaagg acatgactgg tagtctggat
    12661 gaggtggcga ttaaggctat tattgatttg gataaaagtc tgacaaatct caatgaccgt
    12721 aaggaagctg tcttagctaa gattcaagaa caaggtaagt tgaccaagga attggaagaa
    12781 gctatcttag ttgccgaaaa attagcagac gttgaagaac tctatcttcc ttataaggaa
    12841 aagcgtcgta ccaaggcaac cattgcccgt gaagctggac tctttcctct tgctcgcttg
    12901 attttgcaga atatagttga cttagagaaa gaagctgaaa agttcgtctg tgaaggattt
    12961 gcgactggca aggaagcctt gaccggtgca gttgatattt tggtcgaagc cttatcggaa
    13021 gatgtgacct tgcgttctat gacttatcag gaagtgctga gacactctaa acttacttct
    13081 caagccaagg atgaaagtct tgatgaaaag caggtttttc agatttatta tgatttttca
    13141 gagacagttg gaactatgca aggctatcgt accttggctc tcaatcgtgg ggagaaactt
    13201 ggtgtcttga agatcggttt tgaacatgcg acggaccgta ttcttgcctt ctttgctact
    13261 cgtttcaagg tgaaaaatgc ttatattgat gaagttgttc agcaatccgt taagaaaaag
    13321 gtcttgcctg ctatcgagcg tcgtattcgg acagaattaa ctgagaaagc tgaagaagga
    13381 gctatccaac ttttttctga caatctgcgc aatctcctct tggttgctcc actgaaaggg
    13441 cgcgtggttc ttggatttga cccagccttt cgtacaggtg ccaagttagc tgtcgtggat
    13501 gcaacaggaa aaatgctgac aactcaggtt atttatcctg ttaaaccagc atcagctcgt
    13561 caaatcgaag aagccaagaa agatttagca gatttaattg gtcaatacgg tgtagagatt
    13621 attgccattg gaaatggaac ggccagtcgt gaaagtgaag cttttgtagc ggaagttctg
    13681 aaagatttcc ctgaagtcag ctatgttatc gttaatgaaa gtggtgcttc tgtctattct
    13741 gccagcgaac ttgctcgtca ggagtttcca gacttgaccg ttgaaaaacg ctctgccatt
    13801 tctatcgccc gtcgtttgca agatcctctt gcggaattgg tcaaaatcga tcctaagtca
    13861 attggtgtcg gtcaatacca acacgatgtc agtcagaaga aactatctga gagtctggac
    13921 tttgttgtcg atacagtggt taaccaagtt ggtgtcaatg tcaatacagc tagcccagct
    13981 cttctttcac acgtagctgg actcaacaaa actatctctg aaaatattgt caaataccgc
    14041 gaggaagaag gaaaaatcac ttcacgcgcc caaatcaaga aagttcctcg tctgggagcc
    14101 aaggcctttg agcaggctgc tggtttcctt cgtatccctg aaagtagcaa tatccttgat
    14161 aatacaggag ttcacccaga gaattacact gcagttaagg aactcttcaa acgtttagat
    14221 attaaagacc taaacgaaga agcccaaagc aaactcaagt ccctttcagt caaggaaatg
    14281 gctcaagagc tagacctcgg tccagaaacc cttaaagata tcattgcaga tcttctcaaa
    14341 ccaggtcgag atttccgtga ttcctttgac gcacctgtgc ttcgccaaga tgtcctagat
    14401 atcaaagacc tagtggtagg tcagaagcta gaaggtgttg tgcgtaacgt tgttgacttc
    14461 ggtgccttcg ttgatatcgg gattcacgag gacggcttga ttcatatttc tcatatgagt
    14521 cgcaagttta tcaaacaccc tagtcaagtg gtgtcagttg gagatttggt gaccgtttgg
    14581 gtcaagaaaa ttgatactga acgtgaaaaa gttaatctgt cgctcctcgc tccaaatgaa
    14641 actgactgat tatgtcaagc aggtttcact agaagacttc gggagagctt ttatccatca
    14701 tgtccagtgg aataggcgtc tacgttcgac aggtgggcga tttttcccca aagatgggca
    14761 tctggatttt aatcccaagg tttatcagaa actgggtatg gaggttttta ggaaaattgt
    14821 ccgacatgaa ctctgtcatt atcaccttta tttccaaggg aagggctatc aacacaagga
    14881 tcgggatttt aaggaactgt tgaaagcagt ggatggatta aggtttgtac catccttgcc
    14941 caatagtaac tctaaaccac tcaagcttta tcgttgtcaa tcctgccagc aaaggtatca
    15001 gcgcaagcgt aggattgata ccaaacgcta tcgctgtgga ctttgtcgag gtaaattgct
    15061 tctgataaat cagcctgagg actgatgaaa gccgagcctc cccgtgatat actatgtcta
    15121 acctagcaga aagaggaaat atcatgaaca gtaaatttta taaaatgaga cgcaatcgca
    15181 tgatttcagg agttctggca ggtctgtcag acaagtggaa ttttgatgtt accctagttc
    15241 gtttcttgtt tgccattttt acagttgcaa actttggact tggcgtgatt atctatatca
    15301 tcctagcttc tatcatgcct accaaggaag aaatcgaagc agaaatgtac ggaacaggcc
    15361 cacgtaaacg caaagaagcc caagccattg acgacaatga aggctggttt tggtgaggtt
    15421 ctacagaaga tttggaataa gcaaaaagct ttaaatcaat agtctaaact gcttgattta
    15481 aagctttttt acttttatac tcaataaaaa tcaaagtgca aactaggaag ccagccacag
    15541 gctgtaattt agtcggcaat gtgaagttga catagtttgc actttgattt ttgaatagta
    15601 ttaataatat ttcgccagct tcatccacaa actatagtgg attggaacta gaataggaca
    15661 cctatacttc taaaaaattg ttagaaattg atttgactgt cctgatcgat ttgtcctgtt
    15721 cttatttcat tttactataa aagcagtaat ttaaacgcag ttttttaatc tatttttgct
    15781 gttgagacaa tacatttttg gaaaaatggt ggatgctgat aacaactgat aaccagcaaa
    15841 taacataagc agtgccggta aattctgtac cgataaagtg tgtgtgttca actaagagct
    15901 gaccgatgaa tggagagagc agatagagaa gtccgatgag tatatgttct ttgtgtttca
    15961 ttaaagcgca ccttctttcc ttataggttg aacgacttgc aagtgttaaa ttgaatggta
    16021 tgttatctag gtaaccttac taaaatgtta gttcccgctt cctccttttc aaagtaagcc
    16081 ttttcacact tatattttac aactttaaaa ataggaaatc aaatcatttt ctaagtaatt
    16141 ttgcttatat ttcacccaat cttacaaaaa tgtaagatta aagtctcttt tgtaaggtta
    16201 ggttatggca agcggtcttt ttttgatgta aactagactc ataaagaaca aaggagtaac
    16261 atcatgaaac aaatcttaca taagaaaact agaaaaccaa gtcacaaaga aattgagcgc
    16321 gttcagctgg gatgcactat gatgcaagct acatttcatt tgatgggata ttaagaaagg
    16381 agattctcat gacactttta gatgtaaaac acgttcaaaa aatttataaa acacgttttc
    16441 agggcaacca agtagaagcc ctcaaggata ttcactttac cgtcgaaaag ggtgactacg
    16501 ttgccatcat gggtgagtct ggttctggta aatcaactct tctcaatatt ctagctatgc
    16561 tggataaacc aagtcgtggt caggtttact tgaatggaac tgacaccgca accattaaaa
    16621 attcacaggc ctctagcttc cgtcgtgaaa agttgggctt tgtcttccaa gactttaact
    16681 tgctagatac tctatctgta aaggacaata tcttgcttcc gcttgtcttg tcaagaagac
    16741 ctattacaga gatgatgaag aaattggtgg tgacagctga gaatctggga ataaaccaat
    16801 tacaagagaa gtacccttac gagatttctg gtggtcagaa acagcgtgta gcagtagccc
    16861 gcgccatcat cacagaacct gaaattctcc ttgcggacga accgacagga gctcttgact
    16921 ccaagtcatc tgcagcctta cttgatgtct ttgatgaaat caatgagcgc ggccaaacca
    16981 ttctcatggt aacccactca acagcagcag ctagcagagc taaacgtgta ctctttatca
    17041 aagacggcat tctttacaat caaatctacc gtggagagaa gacagaacgt cagatgttcc
    17101 aagaaatctc tgataccttg actgtcatgg caagcgaggt gaattagtat gtttcgatta
    17161 accaataagt tagcggtatc gaacttgatt aaaaaccgca aactctacta tccttttgcg
    17221 ctggctgttc tcttggcagt cactgtcacc tatctctttt actctctaac cttcaatcct
    17281 aagattgcgg aaatccgtgg aggaacaacc attcaggcta cacttggatt tggtatgttt
    17341 gtcgtcaccc ttgcgtcagc cattatcgtt ctctatgcca atagttttgt catgaagaac
    17401 cgttccaagg aactaggaat ttatggcatg ttgggcttgg agaagcgtca tcttatcagt
    17461 atgaccttta aggagttagt ggtatttggg attctaactg ttggagcggg tatcggtatt
    17521 ggagccttgt ttgacaagtt aattttcgct ttcctgctca aactaatgaa attgaaggtt
    17581 gagctggttg ctaccttcca gacgaaagtt gtcattacag tgcttgttgt cttcggtttg
    17641 attttcctag gcctcatgtt cctgaatgcc cttcgaatcg cccgtatgaa tgccctccag
    17701 ctctctcgtg agaaagctag tggagagaaa aaaggtcgct tccttcctct ccaaaccatt
    17761 cttggttcca taagtttagg aattggctat tatcttgccc ttacggtaaa agatcctctt
    17821 acagccttaa caaccttctt catagctgtt ttactggtta tctttgggac ttatctcttg
    17881 tttaatgcag ggattaccgt tttcctccaa atcttaaaga aaaataagaa atactattac
    17941 caaccaaata acctcatatc tgtttctaac ttgattttcc gtatgaagaa aaatgcagtt
    18001 ggactagcca ccatcgctat cttgtcaaca atggttttgg taaccatgtc agcagcgaca
    18061 agcattttca attcctcaga aagctttaaa aaagttctaa atcctcatga ttttggggtt
    18121 tcagggcaaa atgttgaaaa agaagacttg gacaaactct tgagccagtt tgcaagtgac
    18181 aaaggttata agattaaaga aaaagaagta tttcgttaca cttactttgc tgttgcgaat
    18241 caagaaggaa ccaagttaac tatttttgaa aaaggacaaa accgtgtcca accaaaaaca
    18301 gttttcatgg tatttgacca aaaagattat gaaaatatga ctggtcaaaa actgtctcta
    18361 tcaggaaatg aggtcggact ctttgcaaag aatgagggag ttaaagaaca gaaagctcta
    18421 actctaaatg atcatcaatt ttctgtaaaa gaagaattta ctaaagattt tattgtcaac
    18481 catgttccaa atcagtttaa tattttgact gctgattaca attaccttgt tgtacctgat
    18541 ttacaagcct ttttggatca attcccagat tcggctatct ataatcagtt ttacggtggt
    18601 atgaatgtaa atgccagtga agcagaacaa ctcaaggtcg ctgaggagta tgaaaaatac
    18661 ttacaaaagt ttaatgctca attaaacact gaaggtaact atgtgtatgg tagcactcta
    18721 gcagatgcta gttctcagat gagtgccctc tttggtggtg tcttctttat cggtattttc
    18781 ctatccatta tctttatggt cggaactgtt ctggtcatct actacaaaca aatttctgaa
    18841 ggctacgaag accgtgaacg ctttattatc ttgcagaaag tcggtttgga ccaaaagcaa
    18901 atcaagcaaa ccatcaacaa acaggtttta actgttttct tccttccttt gctctttgcc
    18961 ttcatacatc tcgcctttgc ctaccatatg cttagcctga ttttaaaagt gattggtgta
    19021 ctggatacga ctatgatgtt gattgtgacc ttgtctatct gcgctatctt cctcatcgcc
    19081 tatgtgctga ttttcatgat tacttcaaga agttatcgca agattgtgca aatgtaaaaa
    19141 agatacctcg acttcaaaat cgaggtattt cttgtattct aaatgctgaa aagttgttcg
    19201 agcaggaagg taactcccat ggtcaagaga ccaatagcaa ggttccgaat catagctgtt
    19261 ctagtcggat cctttccaag tctggcacta gtgtaaccag tgagaagaag ggccacaccg
    19321 acaataagga cagtagcagg gatgcgatat tcacttggga atatggtcac tgacagcatt
    19381 ggaggcaaac ttctaaggaa aaaggcaacg aagctagaaa tggcagcgtg ccaaggattg
    19441 gtaaattctt catactcaat cccatatttt tcctctacca gagccttgag tggattttta
    19501 agaaagatct tattggtcaa gagttgggca gaagttttgc attctccatt ttggatataa
    19561 gcagcataga gggatttttt ggctagttcc ctatcttggt ctaacaagag tttttctcgc
    19621 gaaacggcag cttcctcggt atcttttgga gttgaaacgg atacatattc tccaccagcc
    19681 attgaaaagg caccagctaa gatagccgca aatcctgata aaaagataat ccagatattg
    19741 gtcgtggcac tggcaacccc gataaccaca ccagcaatgg aaataattcc atcgttagca
    19801 ccaagaacac ctgcgcgcag gatatttaaa cgacctgcaa aatttgaatc gatttcgtga
    19861 tttgtttctg acgctaaatt tcaagttcaa gttagccatc aagaagtctt ctctgggtga
    19921 cttgtagttc aagcattttt taggatagtt gttaatccac ttttcgatga atgcgacttc
    19981 tttgggagtc attttcttgg ttcccttagg taaccatcta tgaatgagcc tgttgtgatt
    20041 ctcattagtt cccctttccc aagaggcata ggggtgcgca taata
//
LOCUS       DAVKMO010000036        19687 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVKMO010000036 DAVKMO010000000
VERSION     DAVKMO010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19687
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.036"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            180..2078
                     /gene="glgB"
                     /locus_tag="VW361_001434"
     CDS             180..2078
                     /gene="glgB"
                     /locus_tag="VW361_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU9744456.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTN"
     gene            2098..3240
                     /locus_tag="VW361_001435"
     CDS             2098..3240
                     /locus_tag="VW361_001435"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU9744457.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3230..4369
                     /gene="glgD"
                     /locus_tag="VW361_001436"
     CDS             3230..4369
                     /gene="glgD"
                     /locus_tag="VW361_001436"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU9744458.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4366..5799
                     /gene="glgA"
                     /locus_tag="VW361_001437"
     CDS             4366..5799
                     /gene="glgA"
                     /locus_tag="VW361_001437"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU9744459.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLIKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSANITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5858..6229
                     /locus_tag="VW361_001438"
     CDS             5858..6229
                     /locus_tag="VW361_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU9744460.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6174..6503
                     /locus_tag="VW361_001439"
     CDS             6174..6503
                     /locus_tag="VW361_001439"
                     /inference="COORDINATES: protein motif:HMM:NF012905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU9744461.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            6512..7627
                     /locus_tag="VW361_001440"
     CDS             6512..7627
                     /locus_tag="VW361_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEU9744462.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFNKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(7624..8070)
                     /locus_tag="VW361_001441"
     CDS             complement(7624..8070)
                     /locus_tag="VW361_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU9744463.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8234..9538
                     /gene="eno"
                     /locus_tag="VW361_001442"
     CDS             8234..9538
                     /gene="eno"
                     /locus_tag="VW361_001442"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU9744464.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            complement(9676..10122)
                     /locus_tag="VW361_001443"
     CDS             complement(9676..10122)
                     /locus_tag="VW361_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9744465.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(10022..10234)
                     /locus_tag="VW361_001444"
                     /pseudo
     CDS             complement(10022..10234)
                     /locus_tag="VW361_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10332..10850)
                     /locus_tag="VW361_001445"
                     /pseudo
     CDS             complement(10332..10850)
                     /locus_tag="VW361_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            10904..11079
                     /locus_tag="VW361_001446"
                     /pseudo
     CDS             10904..11079
                     /locus_tag="VW361_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            11279..14554
                     /gene="rexB"
                     /locus_tag="VW361_001447"
     CDS             11279..14554
                     /gene="rexB"
                     /locus_tag="VW361_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU9744466.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRTDLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADSKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            14551..18201
                     /gene="addA"
                     /locus_tag="VW361_001448"
     CDS             14551..18201
                     /gene="addA"
                     /locus_tag="VW361_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU9744467.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVELKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNSQKWL
                     SDSFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQSVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGRLILLKENFRSSSEVLSTTNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALKMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEAQVVKV"
     gene            18371..19549
                     /locus_tag="VW361_001449"
     CDS             18371..19549
                     /locus_tag="VW361_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744468.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         5964 a         3765 c         4247 g         5711 t
ORIGIN      
        1 tagaaaaaga aaggcgtttt cgcaattttt tgaaaaaata ttgatttaca attgaacgag
       61 taagtgaact tgttgtagat tttcaaaata attaaagaag tatagtaatt tacttgaatc
      121 ttctctaaaa aggtagtata ataaaaacat agaaaacgct tacaggagaa ggggagtata
      181 tggataatag agaagcatta aaaaccttta tgacgggtga aaatttttat ctccaacatt
      241 atctaggagc acatagggaa gaactaaatg gagagcatgg ctataccttc cgtgtttggg
      301 cacctaatgc tcaggctgtt cacttggttg gtgattttac caattggatt gaaaatcaga
      361 ttccaatggt aagaaatgac tttggggtct gggaagtctt taccaatatg gctcaagaag
      421 ggcatattta caaatatcat gtcacacgtc aaaatggtca tcaactgatg aagattgacc
      481 cttttgctgt caggtatgag gctcgtccag gaacaggggc aatcttaaca gagcttcctg
      541 agaagaaatg gaaggatgga ctttggctgg cacgaagaaa acgttggggc tttgaagagc
      601 gtcctgtcaa tatttatgaa gttcacgctg gatcatggaa aagaaattct gatggcagtc
      661 cttatagttt tgcccagctc aaggatgaac tcattcctta tctcgttgaa atgaactata
      721 ctcatattga gtttatgccc ttgatgtccc atcctttggg cttgagttgg gggtatcagc
      781 ttatgggtta cttcgcttta gagcatgctt atggcagacc agaggagttt caagattttg
      841 tcgaggagtg tcatacccat aatattgggg ttattgtgga ctgggtacca ggtcacttta
      901 ccatcaacga tgatgcctta gcctattatg atgggacacc gacttttgaa taccaagacc
      961 ataataaggc tcataaccat ggttggggtg cccttaattt tgaccttgga aaaaatgaag
     1021 tccagtcctt cttaatttct tgcattaagc attggattga tgtctatcat ttggatggta
     1081 ttcgtgtgga tgctgttagc aacatgctct atttggacta tgatgatgct ccatggacac
     1141 ctaataaaga tggcggaaat ctcaactatg aaggttatta ttttcttcaa cgcttgaatg
     1201 aagttattaa gttagaatat ccagatgtga tgatgattgc agaagaaagt tcgtctgcaa
     1261 ccaagattac gggaatgaaa gagattggtg gtctaggatt tgactacaaa tggaacatgg
     1321 gctggatgaa tgatatcctc cgtttctacg aagaagatcc gatttatcgt aaatatgact
     1381 ttaacctggt gactttcagc tttatgtatg ttttcaagga gaattatctc ttgccattct
     1441 cgcacgatga agtggttcat ggcaagaaga gtatgatgca taagatgtgg ggagatcgtt
     1501 acaatcaatt tgcaggcttg cgcaatctct atacgtacca aatttgtcac cctggtaaga
     1561 aattgctctt catgggtagc gaatacggtc aattcctaga atggaaatct gaagaacagt
     1621 tggaatggtc taacctagaa gacccaatga atgctaagat gaagtatttc gcttctcagc
     1681 taaaccagtt ttacaaagat catcgctgtc tgtgggaaat tgataccagc tatgatggta
     1741 ttgaaatcat tgatgcggat aatcgagacc agagtgttct ttcctttatt cgtaagggta
     1801 aaaagggaga aatgttagtc tgtatcttta acatggtacc tgttgagcgg aaagatttta
     1861 caatcggact acccgttgca ggaatttacg aagaagtatg gaatactgag ttggaagagt
     1921 ggggaggtgt ttggaaagaa cataatcaaa ctgttcaaac gcaagaagga ctatggaaag
     1981 attatgagca gaccttaacc tttactctac cggctatggg agcaagtgta tggaaaatca
     2041 aacgtcgctt gaaatctact aaaaccgtca caaattaaaa ccaaaaagga gtagaaaatg
     2101 aaaaatgaaa tgttagcttt gattcttgct ggtgggcaag gaactcgtct cggtaaactc
     2161 actcaaagca tcgcaaaacc agctgtgcaa tttggtgggc gctaccgtat cattgacttt
     2221 gccctatcaa actgtgccaa ctcagggatt cataatgttg gggtcgttac acagtatcaa
     2281 ccacttgctc tcaacaacca tattgggaat ggttcaagct ggggactaga cggtattaat
     2341 tcaggcgtct ctattcttca accttattct gcaagtgaag gaaatcgttg gtttgaggga
     2401 actagtcacg ctatttacca aaatatcgac tatatcgaca gtgtcaatcc tgagtatgtc
     2461 ttgattttgt ctggggacca catctacaaa atggactatg atgatatgct ccagtctcat
     2521 aaggataata atgccagctt gacagtagca gttttagacg tccctcttaa agaagcaagc
     2581 cgttttggta tcatgaacac agatgctaac aatcgtattg ttgaatttga agaaaaacca
     2641 gctcaaccta aatctacaaa agcttctatg ggaatctaca tttttgattg gcaacgcctt
     2701 cgtaatatgt tagtcgctgc tgaaaagagc aaggttggca tgtcagactt tggtaaaaat
     2761 gtcattccaa attaccttga gtcaggtgaa agtgtttatg cttacgaatt tagtggttat
     2821 tggaaagatg ttggtactat tgagtcactt tgggaagcga acatggagta tatttctcca
     2881 gaaaatgcct tggatagtcg taaccgtcaa tggaagattt actcaagaaa cttgatttca
     2941 ccaccaaact tcctcggggc aaatgctcat gtggaagact cattagttgt agacggatgt
     3001 ttcgttgatg gaactgttaa acattctatc ctttcaacag gcgcgcaagt tcgcgaagga
     3061 gcggaagtcc ttgattcagt tatcatgagt ggagctatca ttggtcaagg agctaagatt
     3121 aaacgtgcca ttattggtga aggtgcgatt atttctgacg gtgtcgaaat tgatggaaca
     3181 gatgaagtac aagttgtagg atataatgaa gtagtggggg tagcaacaga tgaagattga
     3241 taaatattct gccattttag gaaatacagt tggttttcac aatatgtcga cattgacgga
     3301 ccaccgtcca gtagcaagtt tgccatttgg tgggaaatat cgtttgattg acttcccgct
     3361 ttcaagcctt gctaatgcag gtgttcgtag tgtctttggt attttccagc aggataatat
     3421 cagctcagta tttgaccata ttcgttcagg acgcgagtgg ggcttatcaa cccttcttag
     3481 tcattactat ctaggaattt acaatacccg tgtagaaagt agtacagttg gaaaagaata
     3541 ctaccaacag cttcttactt atttgaaacg ttctggctca aaccaaacgg ttgccctcaa
     3601 ctgcgatgtt cttattaaca ttgatttgaa ccaagttttc cacctacata gtacaacaaa
     3661 agagcctatc actgtagttt ataaaaaact agctaagaaa gatatttcag aagtaaatgc
     3721 aatcttggat gtagatgaaa cagaccatgt tctttctcat aaactctttg atagcaagtc
     3781 aacagctgaa acgttcaata tgtctacaga tatctttgtc gttgatacac cttggttgat
     3841 tgaacacttg gaagaagaag ctaaaaaaga acatccaaag aaattgcgct atgttttacg
     3901 ggatttggct gtaaaagagg gagctttcgc ctacgagtac acgggctatc tagccaatat
     3961 tcactctgtt aaatcttatt atcaagcgaa tatcgatatg cttgaatcac aaaaattcta
     4021 ttctcttttc tcaccaaacc aaaagattta tacaaaggtc aaaaacgaag agccaactta
     4081 ctatgctaat acatctaagg taagcacttc tcagtttgcc tctggtagta ttattgaagg
     4141 tcaagtagct aattctgttc tatcacgtaa tattcatgtc cataaggata gcttggttaa
     4201 agatagcctg ctcttccctc gtgttgttat tggagaaggg gctcaggtcg aatatgctat
     4261 cttggacaaa ggggttgaag ttgagcctgg tgttgtgatt cgaggaactg cagaacatcc
     4321 agttgtggtt aagaaaggtg ctaaagtaac agaggatatt cattcatgaa aattttattt
     4381 gtagcagcag agggtgcacc cttttcaaaa acaggtggtt tgggagacgt cattggcgct
     4441 cttccaaaat cactgataaa agctgggcac gaagttgcag tgattttacc ctactatgat
     4501 atggtagagg ctaaatttgg aaatcagatt gaagatgtac ttcattttga ggtgagcgtt
     4561 ggttggcgca gacagtattg tggaattaag aaaacagtat taaatggtgt aaccttctac
     4621 tttattgaca atcaatatta tttcttccgt ggtcatgttt acggtgattt tgatgacgga
     4681 gaacgctttg cctttttcca actggctgcc attgaggcta tggaaaggat tgactttatt
     4741 cctgatcttc tccatgttca tgactaccat acagctatga ttcctttctt gttgaaggaa
     4801 aaataccgtt ggattcaagc ctatgaggac attgaaacag ttttaaccat tcataattta
     4861 gaattccaag gacaattttc agaaggaatg ttgggtgatt tgtttggagt tggctttgaa
     4921 cgttacgctg atggcaccct tcgatggaac aactgtctga actggatgaa ggcaggtatt
     4981 ctctatgcga accgtgtttc aaccgtttca cctagctatg ctcatgaaat tatgactagt
     5041 cagtttggat gtaatttgga tcagattctt aaaatggagt ctggtaaagt atctggtatc
     5101 gtgaatggga ttgatgctga tctttataat cctcagacgg atgctctttt agactatcat
     5161 ttcaatcagg aagatttgtc tgggaaagcc aaaaataagg caaaattgca agaaagagtt
     5221 ggcttgcctg ttagagcaga cgttccactg gtgggaattg tttctcgttt gacacgtcaa
     5281 aaaggttttg atgtggtggt cgaaagtctt caccatatct tgcaagaaga tgttcagatt
     5341 gttcttttgg gaactggcga tccagccttt gaaggagctt tctcatggtt tgctcagatt
     5401 tacccagaca agctatcagc aaatatcact tttgatgtca aacttgctca ggaaatctac
     5461 gctgcttgtg acctcttcct catgccaagt cgttttgaac cgtgtggctt gtctcaaatg
     5521 atggctatgc gttatggaac cttgccattg gtccatgaag ttggaggctt gcgagataca
     5581 gttcgcgctt tcaatccaat cgaaggaagc ggtactggct ttagctttga caatctatct
     5641 ccttattggt taaattggac tttccaaaca gcattggact tgtatagaaa ccatccagac
     5701 atttggagaa acctacaaaa acaagctatg gagagtgact tctcatggga tacagcctgc
     5761 aagtcatacc ttgacttgta ccatagttta gttaattaat agataaaatc gtatgatgac
     5821 ttcatacgat ttttaggctg tttagagagg agaactgatg tctcaagtaa aaggcttgtg
     5881 tgttttggat gtagatggaa ccttaatcct agaagaagtg attgatcttt tagggagaga
     5941 ggcaggtcat gaggcggaaa tttcgcagat tacaagtcga gcaatgcgag gagagttggt
     6001 ctttgaaagc agtttaagaa aaagagtgtc cttgttggaa ggtcttccta ttttggtctt
     6061 tgataacgtc ttcaactcaa ttcatctatc gctaaatgtc ccagagttca tctctattct
     6121 ccaaaagaat ggcatcctag ttggtctggt gtctggtgga tttacaccaa tagttggaga
     6181 gattagcaaa atcccttggt attgcctatt tcactgccaa ccagcttgaa gtcaaagaag
     6241 gtcttttaac aggaaaatta gttggacaaa ttataagtcc ccaggtcaaa aaagaaactc
     6301 tggaaaaatg gagaaagaaa ctaaaacttt ctaaagaaag aacggtggca atcggtgatg
     6361 gggtcaataa tctattaatg ttgaagtcgg cggagttagg aatcgccttt tgttccaaag
     6421 aaatgctcaa aaaagaaata ccacatcatg ttgacaagag ggatttttta gaagttcttc
     6481 ctttgattga ctgtttagaa tgagggaaaa tatgaagatt gtaattgcac cggattcgtt
     6541 taaggaaagc ttgacagctc aacaggtagc tgaagcaata aaaagaggct tccaacaatc
     6601 gatagcagat gtagaatgtc tcctctgccc tgttggtgat gggggagaag gtactgtaga
     6661 tgctatccga cattctcttg acctaaaaga aaaatggatc caagtgacag acccttttgg
     6721 acaaaaagaa gccatgcgct attttcaaaa aggggaactg gcactatttg aagtagctga
     6781 cttggttggt cttggaaaaa ttccgctaga gaaacgaaat ccacttcaaa tccaaacttg
     6841 tggtattgga gagttgattc tccatctcat ttctaaaggg attaaagata tttatatcgg
     6901 tgttggtggc acggccagta atgatggagg actggggatt gctgctggtt taggttatca
     6961 attttatgat agggatggaa atgtcttgcc tgcttccgat caatccttat taaacttagc
     7021 ttctgtttca acagaaaatt gctataaaat tcctgaaggt gttcaaattc atattctagc
     7081 agatgtcgtg agtcccttat gtggtcatca aggtgcgact tacacttttg gcaatcaaaa
     7141 aggtctacat ccgactatgt ttgcagtcgt agatcaggcg atccaagatt tttatgaaaa
     7201 attctcacct gcaacattag aaattaaagg agcaggagca ggtggaggcc ttgctggtgg
     7261 tttgtgtgcc tttgctcagg caagtatcgt gtctggaatt gatacctgct tggacttaat
     7321 caactttaat aagaaagttt cagatgctga cttggttgtt gttggagaag gaaggcttga
     7381 tagtcaaagc tttgctggga aagcgcctat aggtgttgca aaaagaaccc ctgttggagt
     7441 tcctgttatt gctatttgcg gtagtcttgc tgaagattta cctcccctac catttgaaaa
     7501 tatccaagct gtcttttcta ttttggagaa aagtgaacct ttagaagata gtttgaaaaa
     7561 tgccagtctc tatctggagc gcacggctgc caatattggg cacttattaa atatgtgcaa
     7621 gatttagcta aaccatttct tccataagga tgttttggct ggttcttcct ttttaacttc
     7681 ccaaagtttt ggaaaagcaa gtcgaaggtc tttttcttct acttgaactg gtgcattgct
     7741 atgaataacc aggccaaaag gagaagtaat atgctcttca gatactatgg tggcttgact
     7801 atcagtttct tttgcttctt ttaagtagaa aacttgctta tcaaattcga tagttggtga
     7861 aatcttcaca aatagtggct ctgctttttc ctgaaggttt tctaaaataa ataaaaagcc
     7921 tttttctaac tgagggctat ttgctgtgtc aatatctaca tatccaagaa ctctttcctc
     7981 aaaagtacca agatagcgtc tttgctcatc cggatttatt tttaacccac catgagcttt
     8041 ttcaagtaat tgttttgata aatctgtcat gaaaacagta tatcataaaa gttagcataa
     8101 aacagacaaa agaaagcgat tactttataa agttaaggaa aagttgcaca aagataacgt
     8161 tttttcttga aaaaggaggg gttttaaggt attatagagg tgtaaaaaat ttaactcata
     8221 aggagagtaa aaaatgtcaa ttattactga tgtttacgct cgcgaagtcc tagactcacg
     8281 cggtaaccca acacttgaag tagaagttta cactgaatca ggtgctttcg gacgtggtat
     8341 ggttccatca ggagcttcta ctggtgaaca cgaagcagtt gaacttcgcg acggtgacaa
     8401 atctcgttac ggtggtcttg gtacacaaaa agctgttgac aacgtaaaca acatcattgc
     8461 tgaagctatc attggctacg atgtacgtga tcaacaagct attgaccgtg ctatgatcgc
     8521 acttgacggt actcctaaca aaggtaaatt gggtgcgaat gcaatcctcg gtgtgtctat
     8581 cgctgtagct cgtgctgctg ctgactacct tgaaatccca ctttacagct accttggtgg
     8641 attcaacact aaagttcttc caactccaat gatgaacatc atcaacggtg gttctcactc
     8701 tgacgctcca atcgctttcc aagagttcat gatcttgcca gttggtgcgc caacatttaa
     8761 agaagccctt cgttacggtg ctgaaatctt ccacgctctt aagaaaatcc ttaaatcacg
     8821 tggtttggaa actgccgtag gtgacgaagg tggattcgct cctcgtttcg aaggaactga
     8881 agatggtgtt gaaactatcc ttgctgcgat tgaagctgct ggatatgtac caggtaaaga
     8941 cgtatttatc ggatttgact gtgcttcatc agaattctac gataaagaac gtaaagttta
     9001 cgactacact aaatttgaag gtgaaggtgc tgctgttcgt acatctgcag aacaaatcga
     9061 ctaccttgaa gaattggtta acaaataccc aatcatcact attgaagatg gtatggatga
     9121 aaacgactgg gatggttgga aagctcttac tgaacgtctt ggtaagaaag tacaacttgt
     9181 tggtgacgac ttcttcgtaa caaacactga ctaccttgca cgtggtatcc aagaaggtgc
     9241 tgctaactca atccttatca aagttaacca aatcggtact cttactgaaa cttttgaagc
     9301 tatcgaaatg gctaaagaag ctggttacac tgctgttgta tcacaccgtt caggtgaaac
     9361 tgaagattca acaatcgctg atatcgcagt tgcaactaac gcaggacaaa tcaagactgg
     9421 ttcactttca cgtacagacc gtatcgctaa atacaaccaa ttgcttcgta tcgaagacca
     9481 acttggtgaa gtagctgaat atcgtggatt gaaatcattc tacaacctta aaaaataaaa
     9541 tagttcagtg aactatttta tcccgaacca tgaaattcaa aagttcggcc gttgatttaa
     9601 caacgtttct agcccctcgg attttatccg aagggctatt tttgtattta gaggacaaaa
     9661 aagggacaaa actttttaaa aaatcttttt cataacttta tccagtacat tgattgcttc
     9721 atctttcatg ttctttgtga cgtgagtgta gatggaagta gtgacttcag agtcggaatg
     9781 accaaccctg tccgtgattg tttttaaagg aattttattt tctgataaga tgctaatagt
     9841 ggtgtgtctg aagatgtgag gggacagatg tttgggaatt ggttttttaa ggcgttcgtt
     9901 tgctcgctgg agagacttgc tcaagataga actatgaact ggttttcctg tattggtaac
     9961 aaaaatacgg tcgcttttgt gccaattctt atcggttgtt tcgcttagac aatttatata
    10021 gtcaattgaa acaagaacaa gacaaaagag cctcataaaa ggtattgcaa cttggtaata
    10081 cccttttgag gtgctttttg atatgagccc atgttttctc aataagattg tactcaggcg
    10141 agtagggagg aagaggtaaa agtttatgcc caaactcttc acacaagagt tctagcttcc
    10201 ccattctatg gaatcttgca ttgtccatta atatagtaga ttgaaactag aatagtacac
    10261 ctctacttct aaaacattgt tagaattcga ttttactgtc ctgatcgatt tgtcctgttc
    10321 ttatttcatt tcactataat aaccgatggt gtggttaatg ttggtaagag aaacttctga
    10381 aaccatactt caaaaaagtc gctcgtcatc atctcttcgt aagtcattgg agcgattaat
    10441 tcaccatttg ttagacctgt gctaggtgct ttaaactatt aaaattctta agaaataagg
    10501 ctactttttc tgggtcttgt tcatagtagg tgtggttctt tttttcgagt gtagcccata
    10561 gctttgagtg catagtggat ggtagttgga tgacagccaa attcagaagc tatttcagtc
    10621 aaataagcgt ctggattatc agtaagatag tttttaagtc tatctctatc aacttttctt
    10681 ggttttgttc cttttacttg gtggtttagc tctcctgttt tctcttttag ctttaaccag
    10741 ccataaatgg tattacgtga gatttggaaa acgtgtgatg cttctgttat actacctgtt
    10801 cgctcacaat aagagagaac ttttttacga aaatctattg aatatgccat aagaagatta
    10861 tacctcattg tgtactattt ttggttcatt ttactatagt tcaatcattc tatcaagaat
    10921 attgaatata taaaggcacg taatattaaa acttcttctg attctgatat cgaattagag
    10981 tccgatgttg atggcgataa atcagacaat ctacccgtcg acattaagat actgggacaa
    11041 cacattgaag tgtattccgt acctaagaaa caatcataaa actcaaagcc ttgttaccga
    11101 ggctttttta ttatgtgatt ttcagtagcc agacttattc tatctaatac aagtaaagct
    11161 aagtatttaa gatttagcag atgatgaaga aaagaaagga tggcctaaat attttaacag
    11221 atttacgagg ctaatcatgg tataatatag ggtgatgaaa aattccaacg aggctgagat
    11281 gaaattactt tatactgata ttcgaacttc tttgacagaa attctaacaa gagaggcaga
    11341 agagctagtt gcagctggca agcgggtctt ctacattgcc cccaactctc tttcttttga
    11401 aaaggaacgc gccgtgctgg aatgcttgtc ccagcaggct tctttttcga ttaccgtcac
    11461 gcgctttgct caaatggctc gttatctggt cttgaatgat ttaccagtta aaactactct
    11521 tgatgatatc ggtcttgggt tggcctttta caaatgcctt gccgaactcg atcccaagga
    11581 cttgcgtgtt tatggcgcta ttaagcagga tcctcaattg atccagcagt taattgagct
    11641 ttaccatgag atgaccaaat ctcagatgag ttttttggac ttggagaatt taacagatga
    11701 ggataagagg acggatttac tcttgatttt tgagaaagta acagcctatc ttaatcaagg
    11761 tcagttagcc cagggaagtc agttgtccca tttgattgag gctattgaga atgacaaggt
    11821 aagtagtgat tttaatcaaa tcaccttggt cattgacggc tttactcgtt tttctgctga
    11881 ggaagagcgg gttgtggact tacttcacgg caaaggtgtt gagattgtta tcggggctta
    11941 tgctagtaag aaagcctata ccagtccttt tagcgagggc aatctctacc aagccagcgt
    12001 aaaatttctc catcatctgg cttctaaata ccaaacgcct gctcaggact gttctcaaac
    12061 tcatgagaag atggatagtt ttgacaaggc ctctcgtttg ttggagtctt cttatgactt
    12121 ttcagaactc gctttggatg tcgatgagaa agaccgtgaa aatttacaaa tctggtcttg
    12181 tttgacgcaa aaggaggagt tggagctagt agcccgtagc attcgtcaga aattacatga
    12241 gaactcagac ctgagctaca agcattttcg tattctcttg ggggatgtag cttcttacca
    12301 gttatctctc aaaaccattt ttgaccagta tcagattcct ttttatcttg gtagaagcga
    12361 agccatggct catcatccct tgactcagtt tgtcgagtct attttagctt taaaacgtta
    12421 ccgttttcgt caggaggatt tgattaatct tcttagaact gatttgtata ctgacctcag
    12481 tcagtctgat attgatgctt ttgagcaata tatccgctat cttggtatca atggcttgcc
    12541 agcctttcag caaaccttca ccaaatccca ccatggaaaa tttaatcttg agcgtttgaa
    12601 tgtcctccgc ctgagaattt tagcacctct tgaaaccctc tttgccagcc gaaaacaaaa
    12661 ggctgaaaaa ctcctacaaa aatggagtgt ctttctaaaa gaaggagctg tgaccaagca
    12721 gttacaagat ttgacaacca ctttggaagc tgtagaacag gaaagacaag ccgaagtttg
    12781 gaaggctttc tgccatgttt tagaacaatt tgcgactgtt tttgctggtt cacaggttag
    12841 tctggaagac ttcctagcct tgctccattc tggaatgagt ttgtcccaat accgtaccat
    12901 tccagcaaca gtggacactg ttctggtgca gagttacgat ttgattgcac cattgactgc
    12961 tgactttgtc tatgctattg gactaactca ggacaattta ccaaaaattt ctcaaaacac
    13021 cagtcttctg acagatgaag aaaggcaaaa cctaaaccaa gcgaccgaag aaggcgttca
    13081 attactgatt gccagcagtg aaaatctcaa gaaaaatcgc tacactatgc tttccttggt
    13141 caattctgct cgtaagcagt tgttcttgtc ggctccaagc ctttttaacg aaagtgaaag
    13201 taaggaatct gcctatcttc aagagttgat ccattttgga tttaggcgga gagagaagag
    13261 gatgaatcac aaaggactgt ctaaggagga tatggggtcc tatcacagtc ttttgtctag
    13321 tctggttgcc tatcaccagc agggtgagat gagcgatact gagcaagatt tgacttttgt
    13381 caaggttctg tcgcgtgtca taggtaaaaa actagatcag caaggtctgg aaaatccagc
    13441 catcccaatc agtccaagca gcaagacctt agccaaggac accttgcaag ctctctatcc
    13501 tgccaaacag gagttttacc tgtctacgtc gggtttgaca gagttttatc gcaatgaata
    13561 cagttatttc ctacgctacg ttttaggctt gcaggaggaa ttacgtttgc atcctgatgc
    13621 ccgtagtcac gggaatttct tgcatcgtat ctttgaacgc gccttacagt tgcctaatga
    13681 agattccttt gaccaacgtc tagaacaagc tattcaagaa accagtcaag aacgcgaatt
    13741 tgaagctatt tatcaagaaa gtttggaagc ccagtttacc aaggaagttt tgcttgatgt
    13801 tgcacggacg actggacata ttctccgaca caatccagcc atcgaaacca tcaaagaaga
    13861 agcaaatttt ggtggaaaag accaagcctt tattcaatta gacaatggac gcagtgtctt
    13921 tgtacgaggc aaggtggacc ggattgaccg tttgaaagct aatggagcga taggagtagt
    13981 agactacaaa tccagtctga ctcagttcca gtttcctcat ttctttaatg ggctcaattc
    14041 tcagttacca acctatcttg ctgccctaaa aagagaaggg gagcagaact ttttcggcgc
    14101 catgtacttg gaaatggctg aacctgtcca atctctgatg gcggtaaaaa gtcttgcagg
    14161 agcagtggta gaagccagca aatctatgaa ataccaaggg ctcttcttgg aaaaagaaag
    14221 cagttattta ggcgaatttt ataacaaaaa caaggctaat caactgacag atgaggaatt
    14281 tcagctccta ctggactaca atgcctatct ttacaagaaa gctgctgaga agattttagc
    14341 aggccggttc gccatcaatc cttatactga aaatggcaga agcattgccc catacgtcca
    14401 gcaacatcag gctattacag gctttgaagc caattaccat ctgggccaag cccgtttcct
    14461 aaaaaagttg gacctagctg atagcaagcg tctggtcgga gaaaaactca agcaagcttg
    14521 gcttgaaaaa ataagagagg agttgaatcg atgaagctta ttcccttttt aagtgaggag
    14581 gagattcaaa aactgcaaga agcagaagca aattcgagca aggaacagaa gaaaactgcc
    14641 gagcaaatcg aagctatcta cacttctggc cagaatatcc tggtctcagc atcggctggt
    14701 tctggaaaga cctttgtcat ggcagagcgc attctggacc aattggcgcg tggtgtcgaa
    14761 atttctcaac tctttatctc aacctttacc gtcaaggctg caactgaact taaagaacgt
    14821 ttagagaaaa aaatcagcaa gaaaatccaa gaaacagatg atgtcgagct caaacaacac
    14881 ttgggtcgcc agttggcaga cctacccaac gctgccatcg gaaccatgga ctctttcaca
    14941 caaaaattcc ttggcaaaca tggttatctg cttgatattg cacctaattt ccgtatttta
    15001 caaaaccaaa gcgagcaact tcttctcgaa aacgaagtct ttcatgaggt ctttgaagcg
    15061 cattaccaag gtaaacagaa agagaccttt agtcatttgc tgaaaaactt tgctgggcgt
    15121 ggcaaggacg aacggggtct gcgccagcag gtctataaaa tctatgactt cctccaatcc
    15181 accagcaatt ctcaaaagtg gctgagtgac tctttcctca aaggctttga gaaagctgat
    15241 tttaccagtg aaaaagaaaa actgactgag caaatcaaac aagccctttg ggatttggaa
    15301 agctttttcc gttaccatct ggataacgat gccaaggagt ttgcaaaggc tgcctattta
    15361 gaaaatgttc agttaattct ggatgaaatt tgctccctaa atcaggagtc cgatagtcag
    15421 gcttatcagt cagtgcttgc gcgtgttgtc gccatctcta aggagaaaaa cggtcgagct
    15481 ctgactaatg ccagccgtaa ggctgatttg aagcccctgg ctgatgccta caacgaagag
    15541 agaaagaccc agtttactaa actaggacaa ttatcagacc agatagcgat tctcgactat
    15601 caagaacgtt atcatggaga cacttggaaa ctagctaaaa ccttccaatc tttcatgagc
    15661 gattttgtag aggcttatcg tcagagaaaa cgacaggaaa atgcctttga attcgctgat
    15721 atcagccatt acaccattga gattttagaa aatttcccac aagttcgtga gtcttatcag
    15781 gagcgcttcc atgaagtcat ggtcgatgag tatcaggata ccaaccatat tcaagaacgg
    15841 atgctggaat tgttgtctaa tggccacaat cgctttatgg tgggagatat caagcaatcc
    15901 atctatcgtt tccgtcaggc agacccgcag attttcaatg agaaattcca acgctatgcg
    15961 caaaatcctc aagaaggcag gctcattctc ctcaaggaaa atttccgtag tagttcagaa
    16021 gtgctgtcaa caaccaatga tgtctttgaa cgtctcatgg accaagaggt cggcgaaatc
    16081 aactatgata acatgcacca gcttgttttt gccaatacca aactgactcc caatccagac
    16141 aacaaggcag aatttctcct ctacgacaag gacgatacag gtgaggaaga agagagtcaa
    16201 acagaaacga aactaacagg cgaaatgcgc ttagttatca aggagattct gaaacttcat
    16261 caagaaaaag gtgttgcctt taaggaaatt gcccttctga cctccagccg cagtcgtaat
    16321 gaccagattc tcctcgccct gtctgagtac ggaattcctg tcaaaactga cggagagcaa
    16381 aacaattatc tccaatccct agaagtgcaa gtcatgctag acactcttcg tgtcattcac
    16441 aatcccctgc aagactacgc cttggttgcc cttatgaagt ctccaatgtt tggttttgat
    16501 gaggatgagc tagcacgttt gtcccttcag aaagcagagg ataaagtcca cgaaaatctc
    16561 tatgagaaac tggtcaatgc acaaaaaatg gcaagtagtc aaaaaggttt gattcacaca
    16621 gctctagctg aaaaactaaa gcaattcatg gatatcctag cttcttggcg cttgtatgcc
    16681 aaaacccact ctctctatga cttgatttgg aagatttaca acgaccgttt ttattatgac
    16741 tatgttgggg ctttgccgaa tggtcctgct aggcaggcca atctctatgc cctagcactg
    16801 cgtgctgatc aatttgaaaa gagcaatttc aaaggtttgt cgcgttttat tcgtatgatt
    16861 gaccaagtct tagaagccca gcacgatttg gcaagcgtgg ccgtcgcacc gccaaaagat
    16921 gcagtagagc tcatgaccat ccacaagagt aaggggctgg agtttcctta cgtctttatc
    16981 ctcaatatgg atcaagattt caacaagcaa gactctatgt cagaagtcat tctcagtcgt
    17041 cagaatggtc ttggtgtcaa atatattgcc aagatggaga caggggcagt agaagaccac
    17101 tatcctaaaa ccatcaaact ctccattcct agcctgacct ataggcagaa tgaagaggaa
    17161 ttacagctag caagctattc tgagcagatg cgtttgctgt atgttgctat gacgcgggct
    17221 gagaaaaagc tctatcttgt cggcaagggt tctcgtgaaa agctggaagc caagcaatac
    17281 ccagcagcca aaaatgggaa actaaatagc aatactagac tgcaagcacg gaatttccaa
    17341 gattggcttt gggctatcag taaagtgttt actaaggaca agctcaactt tagttatcgt
    17401 tttattggcg aagatcagtt gaccagagaa gctatcggag agttggaaac caagagtcct
    17461 ctccaagata gctcccaagc agacaatcgt cagtcagata ccatcaaaga agctctgaaa
    17521 atgctgaagg aggtggaagt ttataatact cttcaccgcg cagctattga acttcctagt
    17581 gttcaaaccc caagtcaaat caagaaattc tacgaaccag ttatggatat ggaaggtgtc
    17641 gagattgctg gtcaaggtca gtcagtaggc aagaaaatca gcttcgattt gccagatttt
    17701 tcaacaaaag aaaaggtaac tggagctgag attggtagtg ctactcacga actcatgcag
    17761 agaattgacc tcagccagca actaaccctt gctagcctaa cagaaacact caaacaagtt
    17821 caaactagcc aagctgtcag agacaagatc aatcttgata aaattcttgc tttctttgac
    17881 acagtactcg gtcaggaaat tcttgctaat accgaccatc tctatcgcga gcaacctttc
    17941 tccatgctca aacgagacca aaagagtcag gaagactttg ttgtccgtgg tatccttgat
    18001 ggctatctgc tttacgaaaa caaaattgtt ctgttcgact acaagacaga ccgctatgat
    18061 gaaccaagtc aactcgtaga ccgctatcgt ggtcagttag ctctatacga agaggcttta
    18121 tcacgagcct attcgattga aaatattgaa aaatacttga ttttactcgg taaagacgag
    18181 gctcaagttg taaaagtata acttatactc tttgaaaatc tcttcaaacc acgtcagctt
    18241 cgccttgctg tatatatggt tactgacttc gtcagttcta tccacaacct caaaacagtg
    18301 ttttgagctg actgcggcta gctttctagt ttgctctttg atttttattg agtattagaa
    18361 aggagacctc atgacacttc cagttagaaa atccctgcac gatgcagttt tacaggcttc
    18421 gaaagcggat acttgggaac aagctaccaa ggaatggaat gaagtttcct tgatttttaa
    18481 cggtatcggc cgtagcaatt gtgtctgtgg aaatgccatc aaatacgctt atgaactctt
    18541 taacggtgtc acaggccaac gcctctttcc aattggtagc gactgtgttc gtcattttca
    18601 tcgattgtcc cttgaccagc aattggaaga ggaagaaaaa ctgctcagaa aggttgaaaa
    18661 tctaaccaga aaagctcaga aaaaggaaaa aatcaaggtc aataaaagtg actttgacga
    18721 gcgacttcta aaatggctct gggaaaaagg tgttttcaaa cccaatcgtg gcaatcaatt
    18781 tgcgcctgag agagactacc agcttttcct agaagtcttt cagggaggaa gttggaccaa
    18841 ggcggaacca aagaaaaagg ctcggatgga agaagtcctt gaaaagtgta tcaaaccctt
    18901 tttacttggg aaatcggatg accaactcta ccttgtcaag ctaggcaagg agaaaattga
    18961 ctacgaacaa gaactccgta tccaggcaga gaaagaacgc aagaagaggg ataaaatcgc
    19021 caagcaatat gcagacaatc tggttctagc catgggaccc gcagagcgtg cttatcaaga
    19081 ttactttggc tttacagaga ccctgactca agaagaacgc aagtgggaaa aaattctttt
    19141 tggtaaaaat agagcagaac gggctatcaa ggccaaacaa taccaaaaag agctggaaaa
    19201 agaccaacga attgccagtc aggatccaat tgaaagaaaa cagaagcaga cttggctcct
    19261 caattcctat tttcgtgagc ttcctgaaga aaaagctcga ttttctaggc tcttattaga
    19321 atatcgaaaa agtggtgaag tacccttttc aactgaatac ctgtcagatc atctcatcga
    19381 ctttttctat aaaatgaaag cctttgaatt tgaaatcgca ccagaacaag tccgagattt
    19441 tctaaaaaaa agcctgcagg aagaccatcg ctcatcagca caaggaagct ggatagaagg
    19501 aattctcctc aactgcctca aaccattttt agaacgatta gtgatatgag taacacctac
    19561 cgtgtaaatt tcatggtagg tgttattgta ccccaaaata atataaaaca aagtatgaaa
    19621 gcgcatctca attttaagac ttttttgtaa attaagagta taattaaggt atactgcctt
    19681 ttctata
//
LOCUS       DAVKMO010000037        19048 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVKMO010000037 DAVKMO010000000
VERSION     DAVKMO010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19048
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.037"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..411
                     /locus_tag="VW361_001450"
     CDS             <1..411
                     /locus_tag="VW361_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9744469.1"
                     /translation="LFDQVASLLEEREIVTPTYREALITREKSFPTGLDMEFLGKDLP
                     NVAIPHTDIVHNLAEKVVVVRLEKSVTFHNMIAPDKEVEVSLLFFIINNSSSSQTNIL
                     AQLMDFFTGNGHLEDLSKISEPEKLYAYIAEAIA"
     gene            449..751
                     /locus_tag="VW361_001451"
     CDS             449..751
                     /locus_tag="VW361_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9744470.1"
                     /translation="MIKILAACGAGVNSSYQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIRLPAKQNMV"
     gene            759..1563
                     /locus_tag="VW361_001452"
     CDS             join(759..1127,1129..1563)
                     /locus_tag="VW361_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU9744471.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKELANDSGKKKFHAMKAQEIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLIAEDKAYNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIINHKLEF"
     gene            1612..2076
                     /locus_tag="VW361_001453"
     CDS             1612..2076
                     /locus_tag="VW361_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU9744472.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2233..2658
                     /gene="lacA"
                     /locus_tag="VW361_001454"
     CDS             2233..2658
                     /gene="lacA"
                     /locus_tag="VW361_001454"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU9744473.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSHMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2689..3204
                     /gene="lacB"
                     /locus_tag="VW361_001455"
     CDS             2689..3204
                     /gene="lacB"
                     /locus_tag="VW361_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU9744474.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHVETHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3215..4144
                     /locus_tag="VW361_001456"
     CDS             3215..4144
                     /locus_tag="VW361_001456"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU9744475.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            4146..5126
                     /gene="lacD"
                     /locus_tag="VW361_001457"
     CDS             4146..5126
                     /gene="lacD"
                     /locus_tag="VW361_001457"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU9744476.1"
                     /translation="MALTEQKRARLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5360..6196
                     /locus_tag="VW361_001458"
     CDS             5360..6196
                     /locus_tag="VW361_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9744477.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6232..6549
                     /locus_tag="VW361_001459"
     CDS             6232..6549
                     /locus_tag="VW361_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9744478.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6549..8240
                     /locus_tag="VW361_001460"
     CDS             6549..8240
                     /locus_tag="VW361_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9744479.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGASVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            8455..9861
                     /gene="lacG"
                     /locus_tag="VW361_001461"
     CDS             8455..9861
                     /gene="lacG"
                     /locus_tag="VW361_001461"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU9744480.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHACAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVSRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVNNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            9904..10161
                     /locus_tag="VW361_001462"
     CDS             9904..10161
                     /locus_tag="VW361_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU9744481.1"
                     /translation="MFKDFIQSIYEKVYIINFEKYSQIPCLTSEELKSLGKWYVSTGK
                     EWICHSDDDLEEFKNLFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(10440..11201)
                     /locus_tag="VW361_001463"
     CDS             complement(10440..11201)
                     /locus_tag="VW361_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9744482.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNISNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(11383..12345)
                     /gene="nrdF"
                     /locus_tag="VW361_001464"
     CDS             complement(11383..12345)
                     /gene="nrdF"
                     /locus_tag="VW361_001464"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU9744483.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(12533..14692)
                     /gene="nrdE"
                     /locus_tag="VW361_001465"
     CDS             complement(12533..14692)
                     /gene="nrdE"
                     /locus_tag="VW361_001465"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU9744484.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(14773..14991)
                     /gene="nrdH"
                     /locus_tag="VW361_001466"
     CDS             complement(14773..14991)
                     /gene="nrdH"
                     /locus_tag="VW361_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU9744485.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            15342..15605
                     /locus_tag="VW361_001467"
     CDS             15342..15605
                     /locus_tag="VW361_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU9744486.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            15611..17344
                     /gene="ptsP"
                     /locus_tag="VW361_001468"
     CDS             15611..17344
                     /gene="ptsP"
                     /locus_tag="VW361_001468"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU9744487.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            17599..>19048
                     /locus_tag="VW361_001469"
     CDS             17599..>19048
                     /locus_tag="VW361_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU9744488.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTSTNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRENLSNLRTYRRQNSDNTPRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLIFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEERIARIIPLRYRSNHWVPDSRPEQPSLQPTPEPSPSPQPAPSNPIDEK
                     LVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDL
                     PSSDREFYNKAYDLLARIHQDLLDNKGRQVDFE"
BASE COUNT         6004 a         3475 c         3923 g         5646 t
ORIGIN      
        1 ctctttgatc aggtagcaag cttgttggaa gaacgagaaa ttgtcactcc aacttatcgt
       61 gaagccttga tcacgcgtga aaagtcattt ccaactggtt tagatatgga atttctagga
      121 aaggacttgc caaatgtagc gattcctcac acagatattg ttcataatct agctgaaaaa
      181 gtggtggttg ttcgattaga aaaatcagta acttttcaca atatgatagc tcctgataag
      241 gaagtagaag tatccctact cttctttatc attaacaatt caagttcaag tcaaacaaat
      301 attctggctc agttgatgga ctttttcaca ggaaatggac atcttgaaga tttatcaaaa
      361 atttccgaac cagaaaaact ttatgcttac attgctgaag caatcgctta atcttgtcta
      421 ttaaaaaata aaatcggagg aaatccaaat gattaaaatt cttgctgcct gcggtgcagg
      481 tgttaactca agttaccaaa ttaaaagtgc tctagaagaa gaactttcaa accgtggtta
      541 tgatgttcac tgtgatgcag tcatggtgaa agatgtaaac gaagacctta tgaaaggtta
      601 cgatatcttt acaccaatcg ctgcaacaga tcttggtttt gaaccaggta tcccagttat
      661 cgaagctggg ccaatcttat tccgtatacc agcaatgagc gctccagtat ttgacaatat
      721 tagactccct gcgaaacaaa atatggtata gtagttctat gaatgatgaa gcaagtaaac
      781 aactaactga tgcacgattt aagcgtcttg ttggtgttca gcgtaccact tttgaagaga
      841 tgttagctgt attaaaaaca gcttatcaac ttaaacacgc aaaaggtgga cgaaaaccta
      901 aattaagcct agaagacctt cttatggcca ctcttcaata tgtgcgagaa tatcgaactt
      961 atgaagaaat tgcggctgat tttggtatcc acgaaagcaa cttactccgt cggagccaat
     1021 gggttgaagt aactcttgtt caaagtggtg ttacgatttc aagaactcct ctcagttctg
     1081 aggacacggt aatgattgat gcgacggaag tacaaatcaa tcgccctaaa aaaagaatta
     1141 gcgaatgatt ctggtaaaaa gaaatttcac gctatgaagg ctcaagagat tgtcacaagt
     1201 caagggagaa ttgtttcttt ggatatcact gtgaactatt gtcatgatat gaagttgttc
     1261 aaaatgagtc gcagaaatat cggacaagct ggtaaaatct tggctgacag tggttatcaa
     1321 gggctcatga agatatatcc tcaagcacaa actccacgta aatccagcaa actcaagccg
     1381 ctaatagctg aagataaagc ctataaccat gcgctatcta aggagagaag caaagttgag
     1441 aacatctttg ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt
     1501 aaacgcttcg gattacgaat gaatttgatt gctggtatta tcaatcataa actagaattc
     1561 tagttttgca ggaagtctaa taaagaaact agcaaggtca ggccttactt tattggtgga
     1621 catccaggat ttaattgtct tctacttgat gatgaagtct atgaagatta ttatctagag
     1681 tttgagaaag aagagatttg ctctgttcca cgtcctttcc cagaaacagg tatgttggat
     1741 ttccaagata gaagtccatg gctagaggga caaaaagaaa tagatcttag ttatgatctt
     1801 ttcagcacag atgcagtgac tttggatgaa ttgcaatctc gaacaattgc ccttcgttct
     1861 cttaaacatg ataagggatt gaaagtgcat tttgcagaat ttccaaacct catcatctgg
     1921 tcaactttga acaagggacc tttcattacc tttgaaccat ggtctggctt gtcaacattc
     1981 cttgaagaag gagatcattt agaagataag aagaatgttt gtctcttaga agccaatcag
     2041 gttgaagaat tagggtttga gatagaagtt ttataaaaaa gtaaaaaata aataacaaaa
     2101 acaaacacaa actgttgact tcttcaaaca atagtagtat attatgtttg tgaggactaa
     2161 ttgactgttt tttaaagaca gccaatacac tgctggaatc cagcatagaa aaaataaaaa
     2221 ggagtataca atatgtctat tgttatcggt gcagatgctg caggtttgag attgaaagaa
     2281 gttgtgaaag acttcttaga aaaagaaaac ttccaccttg tggatgttac agctgaaggt
     2341 caagactttg ttgatgtgac tctcgctgtt gctgcagaag taaacaaaga agaacaaaac
     2401 cttggtatcg tgattgatgc ttatggagct ggtccattta tggttgcaac taagatcaaa
     2461 ggaatggttg ctgcagaagt atctgacgaa cgttcagctt atatgactcg tggccacaac
     2521 aactcacata tgatcactat gggggcacaa cttgttggtg atgaattggc taaaaacatc
     2581 gctaaaggat ttgttaatgg taaatacgac ggtggacgtc atcaaatccg ggttgacatg
     2641 ttgaacaaaa tgggctaatt agattacagt aagaaaggta agttaaaaat gagaattgca
     2701 attggatgcg accacatcgt aacagatgaa aaaatggcgg tttcagaatt tttgaaatca
     2761 aaaggatatg aagtcattga ctttggtaca tatgaccata cacggactca ctacccaatc
     2821 tttggtaaaa aagtagggga agctgtaact agcggccaag ctgatcttgg agtatgtatc
     2881 tgtggtactg gtgttggtat caacaacgct gtaaataaag ttccaggtgt tcgctctgcc
     2941 ttggttcgtg atatgacaac agccctttat gctaaagaac aattgaacgc caacgttatc
     3001 ggttttggtg gtaagattac tggtgaattg ctcatgtgcg atatcatcga agctttcatc
     3061 catgctgaat acaaaccatc tgaagaaaac aaaaaattga ttgcgaaaat tgaacatgtt
     3121 gaaacacaca atgctcaaca aacagatgca aacttcttca ctgaattcct tgaaaaatgg
     3181 gatcgcggag aataccacga ctaagaggtg acctatgatt ttaacagtca caatgaaccc
     3241 atccattgat atttcctatc ccttggatga gttgaagatt gatactgtca atcgtgtggt
     3301 agatgtaacc aaaacggctg gtggtaaagg gctcaatgtt acacgcgtac tttcagaatt
     3361 tggcgattct gttcttgcta ctggtttagt aggtggcaaa cttggtgagt ttttggttga
     3421 acatatcgat aatcaagtaa agaaagattt cttctcaatt cagggagaaa ctcgtaactg
     3481 tatcgctatt ctccacggag acaaccaaac agaagttctt gaaaaaggtc ctgaagtatt
     3541 ggaacaggaa ggtcaagact ttttggaaca tttcaaaaaa ctcttggagt cagttgaagt
     3601 agtggccatc tcaggtagtc tgccagctgg ccttccagtt gattactatg cgagcttggt
     3661 agaacttgct aatcaagctg gcaagcctgt agtcttggac tgctcaggtg cagcacttca
     3721 ggctgttctt gaatcacccc ataaaccaac agtcatcaaa ccaaataatg aagaattgtc
     3781 tcagcttctt ggaagagaag tttctgagga tttggatgaa ttaaaagaag tacttcaaga
     3841 acctttgttt gcagggattg aatggattat cgtttcactt ggtgctaacg gtacttttgc
     3901 caaacatggt gacactttct acaaggtaga tattcctaga attcaggtgg taaatcctgt
     3961 tggatctgga gactctactg tggcaggaat ttcttcagga cttcttcaca aagaatcgga
     4021 tgcagaatta ctcatcaagg caaatgtcct tggtatgctc aatgctcaag aaaaaatgac
     4081 tggtcatgtc aacatggcca actatcaagt tctatatgat caattaatag taaaagaggt
     4141 ataaaatggc tttaacagaa caaaaacgtg cacgcttaga aaaactttct gatgaaaatg
     4201 gtatcatctc agctcttgca tttgaccaac gtggtgcttt gaaacgcctc atggctcaac
     4261 accaaacaga agaaccaact gtggctcaaa tggaagaact gaaagtcttg gtagcagatg
     4321 aattgactaa atacgcttca tcaatgcttc ttgaccctga gtatggactt ccagcaacta
     4381 aagctcttga tgaaaaagct ggtcttctcc ttgcttatga aaaaacaggt tatgacacaa
     4441 caagtacaaa acgcttgcca gactgcttgg atgtttggtc tgcaaaacgt attaaagaag
     4501 agggtgcaga tgcagttaaa ttcttgcttt actatgatgt agatagttca gacgaactca
     4561 accaagaaaa acaagcttat atcgagcgta tcggttctga gtgtgtggct gaagatatcc
     4621 cattcttcct tgaaatcctt gcttacgatg aaaaaattgc agacgcaggt tctgtagaat
     4681 atgcgaaagt aaaaccacac aaagttatcg gtgctatgaa agtcttttca gacccacgct
     4741 ttaacattga tgtcttgaaa gttgaagttc ctgttaacat taaatatgtt gaaggcttcg
     4801 ctgaaggtga agtggtttac acacgtgaag aagcagcagc cttcttcaaa gcgcaagatg
     4861 aagcaacgaa cttgccatac atttacttga gtgctggtgt atcagctaaa ctcttccaag
     4921 atactcttgt atttgctcat gaatcaggtg caaactttaa cggagttctt tgtggccgtg
     4981 ctacatgggc aggatcagtt gaagcttaca tcaaagatgg tgaagcagca gctcgcgaat
     5041 ggcttcgcac aactggattt gaaaacattg atgagctcaa taaagttctt caaacaacag
     5101 cgacttcatg gaaagaacgt gtgtaagaaa gtcctcctag tttaggaaca tgaatctaaa
     5161 aaaatttaaa aaaagttgta tgtaaaggtt tacaaaataa cttacttgtg ctatacttaa
     5221 atcacaagtt aatacaaggt gagtgttact aagtaatatt aggcatgatc acaggtgaat
     5281 tagaaatcag ctgattttct agttcatttg tggtcatttt ttgtactcat atacttttaa
     5341 gatataaaag gaggttgaca tgtatcgaat tctaaatcca atgaatcaca atgtctcgct
     5401 tgtcagaaat gataagggag aagaggtgat tgtaattggt aaggggattg cattcggaaa
     5461 gaagaagggg gatttgattg ctgaaaatca ggttgagaaa atctttcgga tgaagaccga
     5521 agagtccaga gaaaacttta tggctcttct caaagatgtt ccgcttgatt ttatcacagt
     5581 gacctatgaa atcattgata agctatcaaa gaaatatcat tatccgattc aagagtatct
     5641 ctatgtaacc ttgacagatc atatttactg ttcttatcaa gctctaactc aaggaaggta
     5701 caaggatagt aatctgccag atatttccgc taagtatcct gtcgcttttc aaatcgcaaa
     5761 tgaagctttt gaaatttacc gtcagaagct agcagatcat tttcctgagg acgaaattat
     5821 tcggattgct tatcatttca ttaatgctga aggtgaaaat gaagtggaac ttgtggagtc
     5881 gattgataag aggaaagaaa ttctcaggaa tgttgaagaa gttttaacgg actatgcaat
     5941 tcaacgaact aaaaagaata accatttcta tgatcgcttt atgatccatt tgaattattt
     6001 cttggattat ttagacagat ctagagatga taaccaatca cttctggata tggaagatca
     6061 tattaaacaa tcctatccaa aagccttcga gattggttcc aagatctatg atgtgattac
     6121 gcaacatacg ggtcttgatt tgtataaaag tgaacgagtt tatctagttc tacatatcca
     6181 acgtttattg tcataaaaat ttatttaaaa ctatataagg agaattctat catgaataga
     6241 gaagaagtaa cattgttagg ttttgaaatc gtagcctatg ctggcgatgc tcgttcaaaa
     6301 ctattggaag ccttgaaggc tgctgaagct ggtgattttg aaaaagcgga cgctctggta
     6361 gaggaagctg gtagctgtat tgcagaggct caccacgcgc aaacaagtct attgactaag
     6421 gaagcttcag gtgaggactt ggcttatagt gtaaccatga tgcatggcca agaccactta
     6481 atgacaacta tcttgttaaa agatttgatg catcatttaa ttgaactcta caagagagga
     6541 gttaaataat gaataaacta attgcattta tcgagaaagg aaagcctttc tttgaaaaac
     6601 tatctcgtaa tatctatctt cgtgctattc gtgatggttt cattgcaggt atgcctgtta
     6661 ttctcttctc aagtatcttt atcttgattg cctttgtacc aaactcatgg ggctttaaat
     6721 ggtctgatga agttgtagcc tttctgatga aaccttatag ctattctatg ggtattctgg
     6781 ctctcttggt agctggtaca acagctaagt cattgactga ctcagtaaac cggagcatgg
     6841 aaaaaaccaa tcaaatcaac tatatgtcaa cattgttggc agcaattgtt ggtttgttga
     6901 tgttggcagc tgatcctatc gaaagtggtc tagctactgg attcttgggg acaaaaggtt
     6961 tgctttcagc cttccttgct gccttcgtta ctgtagccat ctataaggtt tgtgttaaga
     7021 acaacgtcac tattcgtatg cctgacgaag ttccaccaaa tatctcacaa gtctttaaag
     7081 atgtgattcc attcactctc tcagttgttt cactttatgc tcttgattta ctagctcgtc
     7141 attttgttgg tgcaagcgta gctgaatcaa tcggtaaatt ctttgcacca ctcttctcag
     7201 cagcagacgg ataccttggt attaccatta tctttggtgc ctttgccttc ttctggtttg
     7261 tgggtattca tggtccatct attgttgaac ctgctatcgc agcaattacc tatgcaaatg
     7321 ctgaagtcaa cttgaacctt ctccaacaag gtatgcacgc tgacaagatt cttacttctg
     7381 gtacacaaat gtttatcgtt accatgggtg gtactggtgc gacactggtt gttccattca
     7441 tgttcatgtg gttaacaaaa tcaaaacgta accgtgcaat cggacgtgct tcagtagttc
     7501 ctaccttctt cggtgtaaat gagccaatct tgtttggtgc acctcttgtt ttgaatccaa
     7561 tcttcttcat tccatttatc tttgctccaa ttgcaaacgt atggatcttt aaattcttta
     7621 ttgaaactct tggaatgaac tcattcactg ctaatctacc atggacaacc ccagctccac
     7681 taggtctagt tcttggtact aacttccaag ttctatcatt cattcttgct gcccttctaa
     7741 tcgtggttga cgttgtcatt tactatccat tccttaaggt ctatgatgaa caaattcttg
     7801 aagaagaacg ttcaggtaag tctaatgatg aattgaaaga aaaagttgct gcaaacttca
     7861 acactgcaaa agcggatgct attcttgaaa aagcaggtgt agaagcagca caaaatacaa
     7921 tcactaaaga aacaaatgtc ctcgttcttt gtgcaggtgg aggaacaagt ggtctccttg
     7981 caaatgctct aaacaaggca gcagcagaat acaatgtccc tgtgaaagca gcagcaggtg
     8041 gctatggtgc tcaccgtgaa atgttgccag agtttgattt ggttatcctt gctcctcaag
     8101 ttgcttcaaa ctttgaagat atgaaggcag aaacagataa gctcggtatt aaacttgcta
     8161 agacagaagg cgctcaatac atcaaattaa ctcgtgatgg aaaaggtgcc ctagcattcg
     8221 tacaagagca attcgattaa ggctaggaac tgtgaaacag tctcccatcg ttacggaaat
     8281 cgctatggcg aatttcctaa tcgccttatt aattcgtcgg taaaaagata tcgtttttac
     8341 ctcctcatgt cacaattcgg tgacttggta caagaagtga gatggagaag gatggctcac
     8401 tgactcctct cctctcactt ttactttatt taaatcaaga aataggtgaa aaaaatgaca
     8461 aaaacacttc caaaagactt tatttttggt ggcgcaacag ctgcctatca agcagaaggt
     8521 gctacacata ctgatggtaa aggaccagta gcgtgggata aatatcttga agataactac
     8581 tggtacactg cagaaccagc cagtgatttt tacaatcgat atccagttga cctcaagcta
     8641 gcagaagagt atggtgtcaa tggcattcga atttctattg cctggtcacg tattttcccg
     8701 actggttatg gtcaagtaaa tgctaaaggt gttgagtttt atcataattt atttgcagag
     8761 tgtcacaaac gtcatgttga gccctttgta actcttcatc actttgacac gccagaagct
     8821 ctccactcaa atggagactt cttaaaccgt gaaaatatcg aacattttgt agactacgct
     8881 gccttctgtt ttgaagaatt tccagaagta aactattgga caacctttaa tgaaattgga
     8941 ccaatcggtg atggtcaata tttggttggg aaattccctc caggtatcca gtacgacctt
     9001 gccaaagtct ttcaatcaca ccacaatatg atggtgtctc atgcatgcgc ggtaaaattg
     9061 tacaaagaga aaggctataa aggggaaatt ggtgttgttc acgccctgcc tactaaatat
     9121 cctctagatc ctgaaaatcc agcagatgtt cgtgcagcag agttggaaga tatcatccac
     9181 aataaattca tcttagacgc aacttatcta ggtcgctatt cagctgaaac catggaaggt
     9241 gtcaaccata tcttatcagt caatggtggt agtttggatc ttcgtgaaga agattttaca
     9301 gcattagaag ctgcaaaaga cttgaatgat ttcctaggaa tcaactacta tatgagtgac
     9361 tggatggaag cctttgatgg agaaactgaa attatccata atggtaaagg tgaaaaagga
     9421 agctctaagt atcaaatcaa aggtattggt cgtcgtgtag ctcctgacta tgtatcacgc
     9481 acggattggg attggattat ctaccctcaa ggtttgtatg accaaatcat gcgtgtgaag
     9541 aaagattatc ctaactacaa gaaaatttat atcactgaaa atggtctcgg ctataaagat
     9601 gagttcgtta ataacactgt ttacgatgat ggtcgtattg attacgtgaa acaacacttg
     9661 gagatcttgt ctgatgcgat tgcagatgga gctaatgtaa aaggttactt catttggtca
     9721 ttaatggatg tcttctcatg gtcaaacggt tatgagaaac gttatggtct cttctacgta
     9781 gattttgaaa ctcaagaacg ttatcctaag aaatcagctc actggtacaa gaaagtagcg
     9841 gaaactcaga ttatagacta gtagaattag tcattagata tagaatttta gtgagtcaaa
     9901 aagatgttca aagattttat ccaatctatt tatgaaaaag tttatattat aaatttcgaa
     9961 aaatactctc aaataccgtg tttgacgagt gaagaattga aaagtcttgg aaaatggtat
    10021 gtctcgactg gtaaagaatg gatttgtcat tcagatgatg atctggaaga atttaaaaat
    10081 ctatttttaa attttatcaa tcctgaagaa tgggatacta tctcctttga ttcagatttt
    10141 atgccgtttc aacaatcgta accaatttct caaaaaagtt aaatcttata tttagtactc
    10201 tgtaaaactc ttatctaatc acgttgctta tactcaatga aaatcaaaga gcaactttaa
    10261 actaggaagc gagtcgcaga tttctcaatg tatagctttg aggaattggg caaaaagtct
    10321 ttgatataga aaaaagcata gtatcaggtg tttcaacacc tgatactatg ctttttattg
    10381 tgggaagatt tacttttttt cttctgaaat tgagttgtta cccaggctct ttcagtttat
    10441 taaggcttga tgactttaat gtgtttagat agcttaaaaa ggattgaatc acttagttta
    10501 gaatctgaaa caatagtatc aagatttgat atattataaa aagtataaaa atcaaactta
    10561 ttgaacttac tatgatctgc gagtaaatat tttttattag aattatttaa agcgatgcgt
    10621 tgagcctctc cctcttcctc gctaaaagta gctagagctc cgttttgaat accattacag
    10681 ctaacgaaag ctttagaaaa ttggagatta gagagatttt gtagggtcaa tgtgccaaca
    10741 aaagcacctg taatatcgcg ataatttcca cctatcaaaa tcaaatctgt taattttcgt
    10801 tcgcttaaaa tcagaaaaac aggtagactg ttggttacga cgcggatatt gtcaataggc
    10861 aactcacgcg caaaaaactc taatgttgtt cctggtccaa tgaaaatagt ttctctttct
    10921 tctactagac tgcctgcaaa atgggctatt tcttgttttt ctgccgtttg gagggcttgt
    10981 ttttcaatat ttgatcgctc attagtcaaa agggagttgg ttcgaagttt ttcagctcca
    11041 ccatgcacac gaatcagcaa atctttatca gctaattcct gtaaatagcg ccttgcagtc
    11101 atatctgaaa cggctatttc gtccataatc tgtttaactg ttatggttcc tttactattt
    11161 actatctcta aaattttggt taatttttct tgtttgagca tattatcacc tcgtttccta
    11221 ctactatctt accataaaca aactcatcat tcaaatacaa aaacaacaaa atgaaacaaa
    11281 aacaaaaata tcgaagtttg ttttcaaaac tttcgatatt tttgttgggt tataactttg
    11341 atgtttctag tttacttttt gatgattgag agtgatggag aattagtcta aaccgtagtt
    11401 atagtcatcg tcttgcatgg cttcaacttc gccaagaagg taaccatttc cgacttgaga
    11461 gaagaagtca tggttggaag ttcctgttga aataccgttc ataacgattg ggttgacatc
    11521 ttcagctgaa tctgggaaaa gtggatcttg tcccatgttc atgagagctt tattggcatt
    11581 gtagcgaagg aaggttttaa cctcttcagt ccaaccaaca ccgtcataaa gactctctgt
    11641 gtagccttct tcattttcat aaagagtata gagtaggtcg tacatccatt ctttgagttt
    11701 ttcttgctct tcttcaggca attcattgaa accaagttgg aatttgtaac caatgtaggt
    11761 tccgtgaaca gactcgtcac gaataatcaa tttaatgatt tctgcaacgt tggctagttt
    11821 gttgttaccg agatagtaga ggggagtgaa gaaaccagag tagaagagga aggtttcgag
    11881 gaagacgctg gcaactttct tttcaagtgg gctgccgttt aggtagattt cgttgacaat
    11941 ctcagccttc ttttgtaggt aaggattggt attggtccat tcgaaaattt cttcaatctc
    12001 agccttagta ttcaaggtag aaaagattga tgagtaagat ttagcgtgga cagattccat
    12061 aaattggatg ttattgaaaa cagcttcctc atgtggtgta cggatgtctg cgcgaagggc
    12121 ttgaacccca gtttcagatt gcatagtgtc aagaagggtt aaaccaccaa aaacttttcc
    12181 gaccaagtct ttctctttgt tagatagctt tctccagtca tccaagtcgt ttgataaggg
    12241 aatacgtgta tcgagccaaa attgctccgt cagtttttcc caagttgatt tgtcgatgac
    12301 atcttcgatg gcattccagt taatggcttt gtagtaagtt tccatttaaa atctctttct
    12361 gtgtttagta ttgcgaactc acaattattt ctactttacc ataattctat aggagtatcg
    12421 cacaaaaagt cggaagcccg acttttaaaa tgttacataa attatgttat gacatagtag
    12481 atttgatttt atctgtgctg cttagggaaa aataatgttt ctatgctaga aactaaatca
    12541 cacagctttc acattggttg gcgccgactt ctccaccgtc atctgtaaag gtacggacgt
    12601 agtagataga cttgattccc ttgttaaagg catagttacg aaggatggac aagtcacgtg
    12661 tcgtttgttt attttccctc ttccattcgt aaaggccttt tggaatgtca ctacgcatga
    12721 agagggtgag tgaaagtcct tgatccacgt gttcagtcgc agcagcgtaa acatcgatga
    12781 ctttacgcat atccatatcg taggcagaag tgtagtaagg aatggtttct gtagacaagc
    12841 cagcagcagg gtagtagatt ttaccaattt tcttctcttg gcgttcttcg atacgttgcg
    12901 taatcgggtg gatagaagca gaaacgtcgt tgatatagct gatagaacca tttggcgcta
    12961 cagcaaggcg attttggtgg taaagaccat cttcttgaac cttgtcgcga agttcagccc
    13021 aatcagcaac accagggata aagacatttt tgaagagttc tttaacacgg tctgatgttg
    13081 gaacaaattc accagttaca tacttgtcaa agtaacttcc gttagcatag tctgattttt
    13141 caaagttgtg gaaggtaata ccacgttcac gcgcaatatt gtttgactct accaaggtcc
    13201 agtagttcat aagcataaag tagatgcttg taaattcaac agactcaggt gaaccatatt
    13261 caatgagttg ttgggcaagg tagctgtgca gtcccatggc accgagacca aaggtgtggg
    13321 cttggctatt tccatggtca atcgttggta cagctacgat atgtgaacta tctgtaacga
    13381 aagtaagggc acgaaccata gcacggatag aacgaccaaa atcaggtgaa gtcatcatgt
    13441 taaccacgtt ggttgaaccc aggttacatg aaacatctgt tcccatttga aggaattctt
    13501 gagcatcgtt gatcaagctt ggttcttgaa cttgaagaat ctcagaacac aagttactca
    13561 tgataatctt tccatcaaca ggatttgcac ggttagccgt atctatgttg actacataag
    13621 gatagccaga ctcttgttgc aatttagaga tttcagtttc caaatcccgc gccttgattt
    13681 ttgtcttgcg aatatttgga tttgcgacca attcatcgta tttttcagta atgtcgatgt
    13741 aattgaatgg cacaccgtat tctttttcta cagagtaagg gctgaagagg tacatttctt
    13801 catttttacg agccaattcg tagaatttat caggtactac aacaccaagt gatagagtct
    13861 tgacacgtac tttttcatca gcgttttctt tcttagttga aaggaaagcg atgatatctg
    13921 ggtgaaagac gttgaggtag acaacaccgg caccttgacg ttgccccaat tggttggagt
    13981 aagagaagct gtcttcaaaa agcttcataa caggaacgac acctgaagca gctccttcat
    14041 agcctttgat aggtgcacca gcttcacgaa ggttgctgag ggtaattccc acaccaccac
    14101 caatacgtga aagttgaaga gctgagttga tagaacgtcc gatagagttc atatcatccg
    14161 tcacttggat taggaaacaa gataccaact ccccacgacg agcacgtcca gcattcaaga
    14221 aggaaggagt agcaggttgg tagcgttggt ggatgatttc attggcaata tcgattgcaa
    14281 cagcttcatt cccatcagcg aaataaaggg cgttgaagaa gacacggtct tccatatttt
    14341 caagatagta ttcaccgtca ttagtcttta aggcatattg attgtaaaat ttataagctg
    14401 ccatgaatga cttgaattgg aagttttggt ctttgataaa ttgagccaat tcttccaaga
    14461 actctggacg gtatttcttg ataaaggctg tttcgatgta gttgtgttca atgaggtaat
    14521 tgattttgtc tttgattgaa tcaaaaacca tagtgtttgg aactacattt tctttaaaga
    14581 aagcatccaa ggcttcctta tctttatgaa gcatgatttg tccattaaca ggacggttaa
    14641 tttcgttatt aagacggaag taagtcacgt cttcaagatg ttttaatccc ataaaatttc
    14701 ccttatctaa ttacaaaaga aaggcttcta agttagccct aaaagcagtt tcttctggat
    14761 gatgtactaa gattatgcta attgtttcag ttttcctggt tggaaacctg aaaagacttc
    14821 agttggtgtt tggataacag gagctgcgct aaaaccgagc tctttaactt gatcgacgta
    14881 ctcaggttgc tcatcaagat tgatttcacg ataagagaca ttattactgt ccaagaaacg
    14941 cttggtcatt ttacattgga cacaattgtt tttagaataa acggttacca ttgtgtaact
    15001 cctcttcaaa atttaatact atcttagtat atcagaaaat aaaattttgt caatgattta
    15061 aactaaatat agtggtgttc ttttgttgtt tttatatata aacacaatat atagtgtttg
    15121 tattgtgaaa tagcaatgat tatcctataa attgtttttg aagaaactat atcctgtgtt
    15181 ttgttatcta ggatagaaga ttttcagcaa gttatctgaa aggaaattga aggaaaatcc
    15241 agaaaatgct tgaaaaaaat cctagaagat ggtataatac taaattgtaa gggttatcac
    15301 atataactca aaaaaagaaa gaacaaaagg agagtcaaac tatggcttct aaagatttcc
    15361 acgtagtggc agaaacaggt attcacgcac gtccagcaac attgttggta caaactgcta
    15421 gcaaatttgc ttcagatatc actcttgagt acaaaggtaa atcagttaac cttaaatcaa
    15481 ttatgggtgt tatgagtctt ggtgttggtc aaggtgctga cgtaactatc tcagctgaag
    15541 gtgcagatgc agatgacgct atcgctgcaa tctcagaaac aatggaaaaa gaaggattgg
    15601 cataagggaa atgacagaaa tgcttaaagg aatcgcagca tctgacggtg ttgcagttgc
    15661 aaaagcatat ctactcgttc agccggattt gtcatttgag actattacag tcgaagatac
    15721 aaacgcagaa gaagctcgcc ttgatgccgc tctacaggca tcacaagacg agctttctgt
    15781 tattcgcgag aaagcagtag gtacgctcgg tgaagaagca gctcaagttt ttgatgctca
    15841 cttaatggtt cttgctgacc cagaaatgat cagccaaatc aaggaaacta tccgtgcgaa
    15901 gaaagtgaat gcagaagcag gtctgaaaga agttacagat atgtttatca ctatctttga
    15961 aggcatggaa gacaacccat acatgcaaga acgcgcagcg gatatccgcg acgtgacaaa
    16021 acgtgtattg gcaaaccttc ttggtaaaaa attgccaaac ccagcttcta tcaatgaaga
    16081 agtgattgtg attgcgcatg acttgactcc ttcagataca gctcaattgg acaaaaactt
    16141 tgtaaaagct tttgtaacca acattggtgg acgtacaagc cactcagcta tcatggcacg
    16201 tacacttgaa attgctgctg tattaggtac aaacaacatc actgaaatcg ttaaagacgg
    16261 tgacatcctt gctgttaacg ggatcactgg agaagtgatt atcaacccaa cagatgaaca
    16321 agcggcagaa tttaaagcag ctggtgaagc ctatgcgaaa caaaaagctg aatgggcact
    16381 tttgaaagat gctcaaacag tgactgctga cggtaaacac ttcgagttgg ctgccaatat
    16441 tggtactcca aaagacgttg aaggtgttaa caacaacggt gcagaagctg ttggacttta
    16501 ccgtacagag ttcttgtaca tggattctca agacttccca actgaagatg agcagtatga
    16561 agcatacaag gctgttcttg aaggaatgaa cggtaaacct gttgtcgttc gtacaatgga
    16621 tatcggtgga gataaggaac ttccttactt cgatatgcct cacgaaatga acccattcct
    16681 tggattccgt gctcttcgta tctctatctc tgagactgga gatgctatgt tccgcacaca
    16741 aatccgtgct cttcttcgtg cgtctgttca cggtcaattg cgtatcatgt tcccaatggt
    16801 tgcgctcttg aaagaattcc gtgcagcgaa agcagtcttt gatgaagaaa aagcaaacct
    16861 tcttgctgaa ggtgttgcag ttgcggataa cattcaagtt ggtatcatga tcgagattcc
    16921 tgcagcggct atgcttgcag accaatttgc taaagaagtt gacttcttct caattggtac
    16981 aaatgacttg atccaatata caatggcagc agaccgtatg aacgaacaag tttcatacct
    17041 ttaccaacca tacaacccat caatcctacg cttgattaac aatgtgatca aagcagctca
    17101 cgctgaaggt aaatgggctg gtatgtgtgg tgagatggct ggtgaccaac aagctgttcc
    17161 acttcttgtc ggaatgggct tggatgagtt ctctatgtca gcaacatctg tacttcgtac
    17221 acgcagcttg atgaagaaac tcgacacagc taagatggaa gagtacgcaa accgtgccct
    17281 tacagaatgc tcaacaatgg aagaagttct tgaacttcaa aaagaatacg ttaattttga
    17341 ttaatcgaaa agtccctgca actcagttac agggactttt tttgatattt taaaaagaat
    17401 tttcaagaaa atctttctta taaaaagtcc aaccttgaaa aagtagtggt cagaacaaaa
    17461 aatacttaaa tggttcataa aattcttgac aagttggaga tttaggagta aactattaac
    17521 cagttaagta atagagagga gtttctgcaa tttagaaatg aattgcaact agaaatatca
    17581 aatagaaaga gagtttcgat gaaaattaat aagaaatacc ttgttggttc tgcggcagct
    17641 ttgattttaa gtgtttgttc ttacgagttg ggactgtatc aagctagaac ggttaaggaa
    17701 aataatcgtg tttcctatat agatggaaaa caagcgacgc aaaaaacgga gaatttgact
    17761 cctgatgagg ttagcaagcg tgaaggaatc aatgctgagc aaatcgtcat caagataaca
    17821 gaccaaggct atgtcacttc acatggcgac cactatcatt attacaatgg taaggttcct
    17881 tatgatgcga ttttcagtga agaattactc atgaaagatc caaactataa gctaaaagat
    17941 gaggatattg ttaatgaggt caagggtgga tatgttatca aggtagatgg aaaatactat
    18001 gtttacctta aggatgctgc ccacgcggat aacgtccgta caaaagagga aatcaatcga
    18061 caaaaacaag aacatagtca gcatcgtgaa ggagggactt caacaaacga tggtgcggta
    18121 gcctttgcac gttcacaggg acgctacacc acagatgatg ggtatatctt caatgcatct
    18181 gatatcattg aggacactgg tgatgcttat atcgttcctc atggagatca ttaccattac
    18241 attcctaaga atgagttatc agctagcgag ttggctgctg cagaagcctt cctatctggt
    18301 cgggaaaatc tgtcaaattt aagaacctat cgccgacaaa atagcgataa cactccaaga
    18361 acaaactggg taccttctgt aagcaatcca ggaactacaa atactaacac aagcaacaac
    18421 agcaacacta acagtcaagc aagtcaaagt aatgacattg atagtctctt gaaacagctc
    18481 tacaaactgc ctttgagtca acgacatgtg gaatcggatg gccttatttt cgacccagcg
    18541 caaatcacaa gtcgaaccgc cagaggtgta gctgtccctc atggtaacca ttaccacttt
    18601 atcccttatg aacaaatgtc tgaattggaa gaacgaattg ctcgtattat tccccttcgt
    18661 tatcgttcaa accattgggt accagattca agaccagaac aaccaagtct acaaccgact
    18721 ccagaaccta gtccaagtcc tcaaccagct ccaagcaatc caattgatga gaaattggtc
    18781 aaagaagctg ttcgaaaagt aggcgatggt tatgtctttg aggagaatgg agtttctcgt
    18841 tatatcccag ccaaggatct ttcagcagaa acagcagcag gcattgatag caaactggcc
    18901 aagcaggaaa gtttatctca taagctagga gctaagaaaa ctgacctccc atctagtgat
    18961 cgagaatttt acaataaggc ttatgactta ctagcaagaa ttcaccaaga tttacttgat
    19021 aataaaggtc gacaagttga ttttgagg
//
LOCUS       DAVKMO010000038        18643 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVKMO010000038 DAVKMO010000000
VERSION     DAVKMO010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18643
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.038"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(117..926)
                     /locus_tag="VW361_001470"
     CDS             complement(117..926)
                     /locus_tag="VW361_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9744489.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(928..1731)
                     /locus_tag="VW361_001471"
     CDS             complement(928..1731)
                     /locus_tag="VW361_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9744490.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(1741..3228)
                     /gene="tacF"
                     /locus_tag="VW361_001472"
     CDS             complement(1741..3228)
                     /gene="tacF"
                     /locus_tag="VW361_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU9744491.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            3564..4271
                     /locus_tag="VW361_001473"
     CDS             3564..4271
                     /locus_tag="VW361_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU9744492.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            4276..5298
                     /locus_tag="VW361_001474"
     CDS             4276..5298
                     /locus_tag="VW361_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9744493.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEDLAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFENAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            5315..6184
                     /gene="licA"
                     /locus_tag="VW361_001475"
     CDS             5315..6184
                     /gene="licA"
                     /locus_tag="VW361_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU9744494.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKITPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     IKGLASYGGSDEK"
     gene            6174..7052
                     /locus_tag="VW361_001476"
     CDS             6174..7052
                     /locus_tag="VW361_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU9744495.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAATHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFVAVANGQL
                     LGLMIVFVAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAALFLGTSLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            7064..7753
                     /locus_tag="VW361_001477"
     CDS             7064..7753
                     /locus_tag="VW361_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU9744496.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            7839..8687
                     /gene="dprA"
                     /locus_tag="VW361_001478"
     CDS             7839..8687
                     /gene="dprA"
                     /locus_tag="VW361_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU9744497.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLALSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDIFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            9569..10612
                     /locus_tag="VW361_001479"
     CDS             9569..10612
                     /locus_tag="VW361_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU9744498.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            10779..12866
                     /gene="topA"
                     /locus_tag="VW361_001480"
     CDS             10779..12866
                     /gene="topA"
                     /locus_tag="VW361_001480"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU9744499.1"
                     /translation="MATATKKTKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLTIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            13087..13446
                     /locus_tag="VW361_001481"
     CDS             13087..13446
                     /locus_tag="VW361_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU9744500.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            13539..14171
                     /locus_tag="VW361_001482"
     CDS             13539..14171
                     /locus_tag="VW361_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU9744501.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDICLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            14215..14871
                     /locus_tag="VW361_001483"
     CDS             14215..14871
                     /locus_tag="VW361_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU9744502.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            14890..15522
                     /locus_tag="VW361_001484"
     CDS             14890..15522
                     /locus_tag="VW361_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEU9744503.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEETINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            15550..15984
                     /locus_tag="VW361_001485"
     CDS             15550..15984
                     /locus_tag="VW361_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEU9744504.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTINAVTDGIDAQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIAYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            15996..17032
                     /gene="leuB"
                     /locus_tag="VW361_001486"
                     /pseudo
     CDS             15996..17032
                     /gene="leuB"
                     /locus_tag="VW361_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            17029..17298
                     /locus_tag="VW361_001487"
     CDS             17029..17298
                     /locus_tag="VW361_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU9744505.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYYIWR"
     gene            17302..17661
                     /gene="leuD"
                     /locus_tag="VW361_001488"
     CDS             17302..17661
                     /gene="leuD"
                     /locus_tag="VW361_001488"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU9744506.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSKWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            17823..18391
                     /locus_tag="VW361_001489"
                     /pseudo
     CDS             17823..18391
                     /locus_tag="VW361_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
BASE COUNT         5844 a         3203 c         3945 g         5651 t
ORIGIN      
        1 ggtttttcaa aaaccttgat atgatgcgtt ttattgtggg aatatgtatt tcattttcta
       61 ctaaaattat gtttttgaat aacctctatc ttagtagtct gtataatccc cctcaatcag
      121 tttttgcgat aagctttaat gctatgacta taccactctt gcatttcttt tgatggtggt
      181 gtcatataat cgccatacat ctgggttaaa aattggtcat attttttggg aacaggcaac
      241 atacggccct caaactcagt taaaatcagt tctttaaagg tatcaactgg gaagatttct
      301 ttcatccctt ccttaccgat cccaactcct ccttcatatt gaggagtgtt ggttacagca
      361 tttttgacta gttgatcaat tttcttgtaa aagtagcgag gattgacaaa tcggagagcg
      421 taccagctac ataatctaag aaaatctttt agtttgctat caccgtgaac tgctcgtgat
      481 tttttgatat aagctagttg acgaagagcc acatacttat agctcttgtc gacaatgctc
      541 aagtctgtaa atcgatcaat tgggaagaca tcgatgaaaa ggctggtatc atgacgcttg
      601 tacttaacat ggtcttctat aacagtagaa gtgtccaaaa tcgatgcgaa attatggaag
      661 taccaagaag atgtatcgta ggaaagaacc ttgtagcgag ggtgattttc ttcttcaata
      721 atcttcagta aacgctcata atcctcacga taaagggaaa tatcaatatc atcatcccaa
      781 ggaatcatac ctttgtggcg gatggctcca agcatggttc cataactgag aaaataagga
      841 atatcatgtt tcttacaagt ctcatcaata tagtccagca gggctagttg aatttcttta
      901 atttcttttt tttctaaata ttgcatccta atcctccaat ttataagcgt gaaattcatg
      961 actgtagaag cgtttttctt ctggtggtag ggtcatataa tctccataaa attgtgtcaa
     1021 aatagtatca aatttttcag gtgcaggaag gcttaaattc tcaaagggta aatcgattgt
     1081 tttatcaaag gtaccacttg ggaagacttc cttttcctta aattttgaag gaataaaagc
     1141 catatactgc ccattttcac gactatattt ttgaatttct ttctcgattt tatttgcaaa
     1201 ataacgagga gaaaccggtc gaaggagcaa ccaaaaggct gttcgtatcc aatcttttaa
     1261 aaggctatcc ttatagacaa tatttttatg tttactgaaa gacagcagtt tgaagctttc
     1321 cagtttataa caagtatcaa tgaccttagg atcatcaaag cgatctatag ggaaaatatc
     1381 gataaagata ccagactcat aggtttttgt atttcgagta tcaataattt tagtcgtact
     1441 gtcggttatc ttgataaagt tgttaaagta gttcttatca gtttctaagg ataggagctt
     1501 atacttgctt ttttcctttt gaaaaatgtt aataaatcgt tggtagtctt ctctaggcat
     1561 ggacagatca atatcgtcgt cccaagggat aaagccctca tgtcgaaccg ccccaatcag
     1621 agtaccgtag ttaataatat agttgatatt gtgcttttta cagagagtat caatataatc
     1681 caaaatttct aattcaattt gtttggcatc ttcaatggtt agttgtttca ttttaaactc
     1741 ctatgatttt ttgaatttat tttttaaggc taggacatgg tttaaaaatt catagaaaat
     1801 gctatctttt gtgaagacaa gtagactaat ataagagata gctgataaca agacaatcaa
     1861 accagtatta atcaaaaatg gcaaattaat gaccatatcc acaggataca cgaaattaat
     1921 caggaaataa attgctacaa aggaaagtga aaagagagag tatcgaacag tatagctaaa
     1981 gatatgtccc aagtggatga gttgttttct atggatgaaa atgatataga aaacaagtag
     2041 agaagcctct gataacatag ttgtcagtaa gtagtattcg ggagctacga tatggttgaa
     2101 aaagaggaga ctattcaagc ccaaattgag tagcccagca aagactgtat agactgtgat
     2161 acgtttttca tagccattgg taaagagaat ttgggaacca agaatggtat ctaaggccag
     2221 gataatcgta cgaaaagcga agagagaggt caagatgccg cctccgatat atttttcact
     2281 accgtaaagt aggatggcat ttggtcctaa aaccatgagt ccaaaactca gtggaatgat
     2341 aaagaagtta aagattcgac tacctctatt aaccagagaa acataggctt ctttgtctcc
     2401 tttccccaga tagtaactga gacgaggcac actcactcca attgcacctg ttacaacccc
     2461 agctataacg gtcacaattc gctgagctat ggtatagtaa ctaacgttga catcaatccc
     2521 tgttttaacg aggaagaggc gatctaaaaa agtgaagagc atattggcat tggcaaagac
     2581 taacatggct gtcagaggga gaaagagtgg tttaaaatca cttaggtgaa tcttaacaag
     2641 tttgatgtct cttttaatcc aaaaataact aatcaggtag ttaatcagcg tcgataaact
     2701 catcacaagt gtatagacaa caatatcgtg ttcattttta acaaataaga aaatagagac
     2761 cagcatcagg atacggatga aggcagtttt gtaaaagaga aaactgtaat tttccagagc
     2821 ttcattgacc cattcgattg aaaaaatctg ggcaatgagt tgaatcccca taacaaggta
     2881 gacctttttg acgattggat tatcagtaaa gaagagagga taggctagga tatagacagc
     2941 agtggtcaaa atcgtacaag cgatgcacaa ataaaaaaga ctagaaaagg ttctgttaag
     3001 atcttttttg ttatccttga cattactgat agcccttaaa ccgtagttat agacaccata
     3061 agttgcaaag ggcaagaaaa atgacaaaat agtgtcgact gagttgaagt aaccatagtc
     3121 agttcggtcc aagacacgcg cgacataggt tccagttagg atgggaaaaa taatattcaa
     3181 gacacgaatt cccatgtaag atagagcatt taattttata cttttcattc aatttacctc
     3241 gtttttcatt atatcataaa gttagctaat aagaaatgaa gggcagtaag tcaagtaatc
     3301 actttgaagt ttcaaatctt aagttttaag ttttctttaa ggaaagtata ttattctgaa
     3361 ggactctaaa atttcgcagc catttattag taattgctac agaattccta gtcattacta
     3421 gaaatggact agtttctttg aataatagaa ctgcataatt ctcctattct agaaggggag
     3481 gaccagtatt tcttttatga taggactaga ttgtggtata atagagagaa taagtttttt
     3541 tagtaagaca aaggagaaaa tagatgattt atgcaggaat tcttgccggt ggaactggca
     3601 cacgcatggg gatcagtaac ttgccaaaac aatttttaga gctaggtgat cgacctattt
     3661 tgattcatac aattgaaaaa tttgtcttgg agccaagtat tgaaaaaatt gtagttggtg
     3721 ttcatggaga ctgggtttct catgcagaag atcttgtaga taaatatctt cctctttata
     3781 aggaacgtat catcattaca aagggtggtg ctgaccgcaa tacaagtatt aagaaaatca
     3841 ttgaagccat tgatgcttat cgtccgctta ctccagagga tatcgttgtt acccacgatt
     3901 ctgttcgtcc atttattaca cttcgcatga ttcaggacaa tatccaactt gcccaaaatc
     3961 atgacgcagt ggacacagtg gtagaagcgg ttgatactat cgttgaaagt accaatggtc
     4021 aatttattac agatattcca aatcgtgctc acctttatca aggacaaaca cctcaaacat
     4081 tccgttgcaa ggacttcatg gacctttatg gatctctttc tgatgaagag aaggaaatct
     4141 tgacagatgc atgtaaaatc tttgtgatca aaggaaaaga tgtggccttg gccaaaggtg
     4201 aatactcaaa tctgaagatt acaaccgtaa cagatttgaa gattgcaaaa agtatgattg
     4261 agaaagacta gtaaaatgat taatcaaatt tatcaactaa ctaagcctaa gtttatcaat
     4321 gtcaaatatc aggaagaggc tattgaccaa gagaatcata tccttatccg tcccaactac
     4381 atggctgtct gtcatgcgga tcagcgttac tatcagggaa aacgtgatcc caagattttg
     4441 aataaaaagc ttccaatggc aatgattcac gagtcatgtg gaaccgtcat ttctgacccg
     4501 accggaacct acgaggttgg tcaaaaagtt gtcatgattc ccaatcagtc tcctatgcag
     4561 agtgatgaag aattctatga aaactacatg acagggaccc atttcttgtc tagtggattt
     4621 gatggcttta tgagagagtt tgtttctctc cctaaagatc gtgtggtggc ttatgatgct
     4681 attgaagata cggttgcagc cattacagag tttgtcagtg tgggcatgca cgctatgaat
     4741 cgtctattga ctcttgctca tagcaagcgg gagcggatcg ccgttattgg agatgggagt
     4801 ttagcttttg tggttgccaa tattatcaac tatactttgc cagaagcaga gattgtggtt
     4861 attggtcgtc attgggaaaa gttggaactc ttctcatttg ccaaagaatg ctatattacg
     4921 gataatattc ctgaagattt ggcctttgac catgcttttg aatgttgtgg tggtgatggt
     4981 actggaccag ctattaatga cttgattcgc tacattcgtc ctcagggaac gattctcatg
     5041 atgggagtta gcgaatataa agtcaatctc aatactcgcg atgccttaga aaagggcttg
     5101 attttggttg ggtcatctcg ttctggtcgc attgattttg aaaatgctat ccaaatgatg
     5161 gaagtcaaga aatttgccaa tcgtcttaaa aatatccttt atctagaaga acctgtaaga
     5221 gaaattaaag atattcatcg tgtctttgca accgatttaa acacagcctt taaaacagtg
     5281 tttaagtggg aagtataagt actggaggtt aattgtggag aaaatcatta aagaaaaaat
     5341 ttcttcctta cttagtcaag aagaggaagt cctcagtgtt gaacaactgg gtggaatgac
     5401 caatcaaaac tatttggcca aaacaacaaa taagcaatac attgttaaat tctttggtaa
     5461 agggacagaa aagcttatca atcgacaaga tgaaaagtac aatcttgaac tactaaagga
     5521 tttaggctta gatgtaaaaa attatctttt tgatattgaa gctggtatca aagtaaatga
     5581 gtatatcgaa tctgcgatta cgcttgattc aacgtcaatc aagaccaagt tcgacaaaat
     5641 tactccaata ttacaaacta ttcatacgtc tgctaaggaa ttaagaggag aatttgctcc
     5701 ttttgaagaa atcaaaaaat acgaatcctt gattgaagaa caaattcctt atgccaacta
     5761 tgaatctgtt agaaatgcag tcttctcctt agagaaaaga ctggctgact taggtgttga
     5821 cagaaaatct tgtcatatcg atttggtgcc tgaaaacttt atcgaatcac ctcaaggacg
     5881 actttatttg attgactggg aatattcatc aatgaatgat ccaatgtggg atttggctgc
     5941 cctcttttta gagtctgaat tcacttccca agaggaagaa actttcttat ctcactatga
     6001 gagtgaccaa acaccggttt ctcatgaaaa gattgctatt tataaaattt tacaagatac
     6061 tatttggagt ctatggactg tctataagga agagcaaggt gaagattttg gtgactatgg
     6121 tgtgaatcgt taccaaagag ctattaaagg tttggcttct tatggaggtt cagatgaaaa
     6181 gtaaaaacgg agttcctttt ggccttctct caggtatttt ctggggcttg ggtctaacgg
     6241 ttagtgctta tatcttttcg atttttacag atttgtcacc ctttgtggtg gctgcaactc
     6301 atgatttttt gagcatcttt atcttactag cttttctctt ggtaaaagaa gggaaagttc
     6361 gcctctcaat tttcttaaat attcgcaatg tcagtgttat cataggagcc ttgctagcag
     6421 gccctatcgg tatgcaggcc aatctttatg cagttaagta tattggaagt tctttagctt
     6481 catctgtatc ggctatttac cctgcgattt cagttctatt ggctttcttc tttttgaagc
     6541 acaagatttc gaaaaatact gtatttggga ttgtcttgat tattggaggg attattgccc
     6601 agacctataa ggttgaacag gttaattctt tctacattgg gattctttgt gctttggttt
     6661 gtgctattgc atggggaagt gagagtgttc ttagctcttt tgccatggaa agtgaattga
     6721 gtgaaatcga agccctctta atccgtcaag taacttcgtt cttgtcctat cttgtgattg
     6781 tgctcttctc tcatcagtca tttgttgcag tagccaatgg acaattgcta ggtctcatga
     6841 ttgtctttgt agcctttgat atgatttcct atttggctta ttatatcgct atcaatcgct
     6901 tgcaaccagc caaggctaca ggcttgaacg tgagctatgt agtatggact gtcttgttcg
     6961 cagctctttt cttgggaaca tcattagata tgctgaccat tatgacgtca cttgtcgtca
     7021 ttgctggagt ttatattatt attaaagaat aaaggagatt cgtgtgaaag ccattatctt
     7081 agcagcggga ttgggaactc gcttgcgtcc tatgactgaa aataccccta aagccttggt
     7141 tcaggttaat caaaaacctt tgattgaata ccaaattgag tttctcaaag aaaaaggaat
     7201 caatgacatc atcatcatcg ttggttatct taaagaacaa ttcgattatt taaaagaaaa
     7261 atacggtgtt cgcctcgttt tcaatgataa atacgctgac tacaataact tttactctct
     7321 ctatcttgta aaagaagaat tggccaacag ctatgttatt gatgctgaca attatctctt
     7381 taaaaatatg ttccgcaatg atttgacacg ttcgacttat tttagtgttt atcgtgaaga
     7441 ttgtaccaac gaatggttct tggtctatgg agatgactac aaggttcaag acattattgt
     7501 tgatagcaag gcaggtcgca tccttagtgg tgtatccttc tgggatgctc caactgcaga
     7561 aaagattgtc agctttatcg acaaggctta tgcaagtggt gaatttgttg atctctactg
     7621 ggacaatatg gttaaggata atatcaaaga gctagatgtc tatgttgaag aattagaagg
     7681 caatagcatt tatgagatcg atagtgtcca agactatcgt aaattagaag aaattcttaa
     7741 aaacgaaaat taaagattcc aacatctgac aaaatagtcg gatgtttttt gattttttac
     7801 gaatagatag atgagtagaa aaagaaatgg agttatttat gaaaattaca aactatgaaa
     7861 tctataagtt aaaaaaatca ggtttgacca atcaacagat tttgaaagtg ctagaatacg
     7921 gtgaaaatgt tgatcaggag cttttgttgg gtgatattgc agatatctca ggttgccgta
     7981 atccagccgt ttttatggaa cgttattttc agatagacga tgcgcatttg tcgaaagagt
     8041 ttcaaaaatt tccatctttc tctattttag atgactgtta tccttgggat ttgagtgaaa
     8101 tatatgatgc gcctgtactt ttattttaca agggaaatct tgacctcctg aaattcccga
     8161 aggtagcggt cgtgggcagt cgtgcttgta gcaaacaggg agctaagtca gttgaaaaag
     8221 tcattcaagg cttggaaaat gaactggtta ttgtcagtgg tctggccaag ggcattgaca
     8281 cagcagctca tatggcagct cttcagaatg gcggaaaaac cattgcagtg attggaacag
     8341 gactggatgt gttttatcct aaagccaaca aacgcttgca agactacatc ggcaatgacc
     8401 atctggctct aagtgaatat ggacctggcg aacaacctct gaaatttcat tttcctgccc
     8461 gtaatcgcat cattgctgga ctttgtcgtg gtgtgattgt agcagaggct aagatgcgtt
     8521 caggtagtct cattacctgt gagcgagcaa tggaagaagg acgcgatatc tttgctattc
     8581 ctggtagcat tttagatgga ctatcagacg gttgccatca tttgattcaa gaaggagcaa
     8641 aattggtcac cagtgggcaa gatgttcttg cggaatttga attttaaaaa tgacctaagc
     8701 tagaattcta agaaaaaatc aattttaaga gaaaatgaac ccaacatttc cataataaaa
     8761 cgcatattag caagttttta acacttgata atatgcgttt tttctaagtg gattagtaga
     8821 gtagaggatt ttttcatata atactcttcg aaaatctctt caaactacgt cagcttccat
     8881 ctgcaacctc aaaacagtat tttgagctga cttcgtcagt cttatctaca acctcaaagc
     8941 agtgctttga gcaacctgtg gctagcttcc tagtttgcgc tttgattttc attgagtata
     9001 agggaaagta tagtgaattg aaataagatg tgaacaactc tatcaggaaa gtcaaattaa
     9061 tttatagaaa tattttagca gccaaggtgc actgttatag attcaataca ctataattta
     9121 gtgtaattga gaaaggagaa atgattgtga ttgatgttgg ctaggttatt ttcaatgatt
     9181 cctaccgtct caaatcttgt cagtaaggaa aaataaattc ttcaaaagta gagattacaa
     9241 ggcttgttta agaaagaatt caaagacctt gacaaataaa aataaaatgg ttattataag
     9301 aaatggtcta aaatagatga tgatactttt cgaaaatctt tttacgtcag ctcagctttg
     9361 ccttgctgtg ttttgagcaa gctacggtta gcttccgagt ttgattttca tttactagaa
     9421 atgaaactga tgagagatat cagtagacat ttgagtcagg atattatgga aaatgataaa
     9481 aagagctcgt gagattggca tatcagacta ctaaagtatt gagtttgtta ggattttagc
     9541 gactagttag ctgggaaagg aagatattgt gacaaataat aaactgtatt cgttgataga
     9601 atttagaaat aaaatatatg aagaattaga actttccaga agtgatttag cgattttact
     9661 atgtgccatg cttatcgcct ctatcggatt aaatatggat tcgactcccg tgattattgg
     9721 agccatgtta atctctcctt tgatgacacc tattctggga gtggggctct ctctagctat
     9781 atttgatttt aaattgttaa gaaaatcttt taaaatatta gctattcaaa ttcttgccag
     9841 tttaatagct tcaacacttt atttttatct ttctcccatt tcgtatgcta gttcggaaat
     9901 tgttgctaga acctctccga ctatttggga tgttctcatt gcttttgtag gagggatagc
     9961 aggtattatt ggtgctagga aaaaagagac caataatatt gttcctggtg ttgctattgc
    10021 aaccgccttg atgcctcctc tttgtacagt aggttatgct attgcttctg ctaatctaaa
    10081 atttatcata ggctcctctt acctattcct catcaattgt agctttattg tcattgcgac
    10141 ttatataggt gttaggttga tgatggttaa gaaacattat tttaaagata atgaagaaga
    10201 ctctaaaatg cgtaggattt tgcttctagt tgctgttttg ctgatgattc cgagtttcat
    10261 ctctgcaacg actttagtga gagaaacgtt gaaaaaagag tcccttaaga aatttatatc
    10321 agagcagttt caggggcata atattttgaa aaaaacctat tctaaaaaga ctcataccct
    10381 aaagctaacc atttcaggaa attatttgac agaagaagaa ctcgatatga tttcaagtaa
    10441 gagaggtgac tatggtttaa gtgatgtttc tgttcaagtt tcacaattgt ctgattcaga
    10501 acaacttagt aaggaagaac tggtggagta tttcttccag tatatcaagg ataaggaagc
    10561 aaaagaaaag gaaaaagcta ataagtttta tacagagtct gaggagcaat aatttcttga
    10621 gaatagctgg tttttctcgt gagtcttcta tgtatatcaa aggaagactg aggttttaag
    10681 tataaaactt ttcttctatt atagtagcta agtcttgaca gggttcaaaa aatggtttac
    10741 actttataaa gtttattact ttgaaaaggt gtgatactgt ggctacggca acaaaaaaga
    10801 caaaatcaac agttaaaaaa aatctagtca tcgtggagtc gcctgctaag gccaagacga
    10861 ttgaaaaata tctaggcaga aactacaagg ttttagccag tgtcgggcat atccgtgatt
    10921 tgaagaaatc cagtatgtcc gtcgatattg aaaataatta tgaaccgcaa tatatcaata
    10981 tccgaggaaa aggccctctt atcaatgact tgaaaaaaga agctaaaaaa gctaataaag
    11041 tttttctcgc gagtgacccg gaccgtgaag gagaagcgat ttcttggcat ttggcccata
    11101 ttctcaactt ggatgaaaat gatgccaacc gtgtggtctt caatgaaatc accaaggatg
    11161 cagtcaaaaa tgcttttaaa gaacctcgta agatcgatat ggacttggtc gatgcccaac
    11221 aagctcgtcg gatcttggat cgcttggtag ggtattcgat ttcgcctatt ttgtggaaga
    11281 aggtcaagaa gggcttgtca gcaggtcgcg ttcagtccat tgcccttaaa ctcatcattg
    11341 accgtgaaaa tgaaatcaat gccttccagc cagaagaata ctggacagtt gatgctgtct
    11401 ttaaaaaggg aaccaaacaa tttcatgctt ccttctatgg agtagatggt aaaaagatga
    11461 aactgaccag caatgacgaa gtcaaggaag tcttgtctcg tctgacgagt aaagactttt
    11521 cagtagatca ggtggataag aaagagcgca agcgcaatgc tcctttaccc tataccactt
    11581 catctatgca gatggatgct gccaataaaa tcaatttccg tactcgaaaa accatgatgg
    11641 ttgcccaaca gctctatgaa ggaattaata tcggttctgg tgttcaaggt ttgattacct
    11701 atatgcgtac cgattcgact cgtatcagtc ctgtagcgca aaatgaggcg gcaagcttca
    11761 ttacggatcg ttttggtagt aagtattcta agcacggtag caaggtcaaa aacgcatcag
    11821 gtgctcagga tgcccatgag gctattcgtc cgtcaagtgt ctttaataca ccagaaagca
    11881 tcgctaagta tctggacaag gatcagctca agctatatac ccttatctgg aatcgttttg
    11941 tggctagcca gatgacagcg gccgtttttg ataccatggc tgttaaattg tctcaaaaag
    12001 gggttcaatt tgctgccaat ggtagtcagg ttaagtttga tggttatctt accatttata
    12061 atgattctga caagaataag atgttaccgg acatggttgt tggagatgtg gtcaaacagg
    12121 tcaatagcaa accagagcaa catttcaccc aaccgcctgc ccgttattct gaagcaacac
    12181 tgattaaaac cttagaggaa aatggggttg gacgtccatc aacctacgcg ccaaccattg
    12241 aaaccattca gaaacgttat tatgttcgcc tggcagccaa acgttttgaa ccgacagagt
    12301 tgggagaaat tgtcaataag ctcatcgttg aatatttccc agatatcgta aacgtgacct
    12361 tcacagctga aatggaaggt aaactggatg atgtcgaagt tggaaaagag cagtggcgac
    12421 gggtcattga tgccttttac aaaccattct ctaaagaagt tgccaaggct gaagaagaaa
    12481 tggaaaaaat ccagattaag gatgaaccag ctggatttga ctgtgaagtg tgtggcagtc
    12541 caatggtcat taaacttggt cgttttggta aattctacgc ttgtagcaat ttcccagatt
    12601 gccgtcatac ccaagcaatc gtgaaagaga ttggtgttga gtgtccaagc tgtcatcagg
    12661 gacaaattat tgagcgaaaa accaagcgta atcgcctatt ctatggttgc aatcgctatc
    12721 cagaatgtga atttacctct tgggacaagc ctgttggtcg tgactgtcca aaatgtggca
    12781 acttcctcat ggagaaaaaa gtccgtggtg gtggcaagca ggttgtttgt agcaaaggcg
    12841 actacgagga agaaaagatt aaataagagg aggggcccga aagtaaattt caggctcctt
    12901 ttggttagaa cttgacaaaa tacatcattt tatgcgaaac tagaagaaga ttattttata
    12961 ctcagtgaga atcaaagagc aaattagaaa gctagtcgca ggttgctcaa agcactactt
    13021 tgaggttgaa gatggaagct gacctggttt gaagagattt tcgaagagta ttaactagga
    13081 gaagttatgc gtcttatcta tctaattatt ggttttttat cgctggcctt ggctattgtt
    13141 ggggttgttt tacccttgtt acctacaaca cctttccttt tgttgtctat tgcttgtttc
    13201 tccagaagtt ccaagcgatt cgaagactgg ctttatcata ccaagctcta tcaaacatat
    13261 gtagctgatt ttcgcgagac taagtctatt acgcgtgaac gaaagaaaaa aatcatcgtc
    13321 tctatctacg tcttgatggg aatttctatt tattttgcac ctcttttacc agtcaaaatc
    13381 ggtctgggtg ctttgaccat ctttatcact tattatcttt tcaaggtcat tccagacaaa
    13441 gaatagttaa aacagtagtt atttgccttg ataaaattga aagcatattc ataacaatat
    13501 gatataataa atttgaagta atattcaagg agaatcaaat gatttacgaa ttttgtgctg
    13561 aaaatgtgac tttacttgaa aaagcgatgc aggctggagc tcgtcggatt gaactctgtg
    13621 ataatctagc agttggtggg acaacaccca gctatggagt gactaaggca gcggttgaac
    13681 tggcagctaa ctacgataca accatcatga ccatgattcg gccacgtggt ggtgactttg
    13741 tctataatga cctagaaatt gctatcatgc tagaagacat ttgtttgact gctcaggctg
    13801 gaagtcaagg ggttgtattt ggagctttaa ctgctgataa aaagttggat aagcctaatc
    13861 tggaaaagtt aattgctgca tcaaaaggaa tggaaattgt ctttcacatg gcctttgatg
    13921 aactaagtga tgaagatcaa ccggaagcta ttgactggct cagtcaagcc ggtgtcactc
    13981 gtatcctaac tcgtgctggt gtgtctggcg actccttaga aaaacgtttt gttcactatc
    14041 acagaatttt ggagtacgct aaaggtaaaa ttgaaattct accaggtggg gggattgacc
    14101 ttgacaaccg tcaaaccttt attgaccagg tgggggtaac acaattgcat ggtactaagg
    14161 ttgtttttta aaaaatagaa aggaactgct agccttgggt agcagttttc acttatgttt
    14221 gaaattttta aatcctatca atttaatcaa gaaaaggctc atgattatgg ttttatagaa
    14281 aatagcgaag tctggacata tagttgccag attttgcaag gtgactttgt catgactgtg
    14341 tccatcactg ctgataatgt gaactttcaa gtctttgacc aagagactgg tgacctttat
    14401 cctcacgttc atatggaaag catgagggga agttttgtcg gaaatgtccg tgaggcttgt
    14461 ctggagattc tttaccagat tcggaaggct tgttttgatg tgcaagattt tatctgtcat
    14521 cagactaagc gtatcatgac tcaagttcag gaaaagtatg gaaaccagtt ggagtatctg
    14581 tgggaaaaat cgcctgatac agctgtattg cgccatgaag gcaatcaaaa gtggtatgcc
    14641 gtcttgatga aaatctcttg gaataagctg gaaaagggca gagaaggaca agtggaagca
    14701 gtcaacctca agcatgacca agtagctaat ttgctttcac aaaaggggat ttatccagcc
    14761 ttccatatga gcaagcgcta ctggattagt gtgtcccttg atgatacttt atcagatgaa
    14821 gaagtactgg aattgataga aaaaagttgg aacttaacct ctaaaaaatg aaatatttta
    14881 ataattttca tgaactttca attagctaaa tattctttac tgaagaaatt ttcagaaaat
    14941 ataggattta ccacaccaga ggaatgtggt gccatcttca aatacctgat tgagaatgtc
    15001 aagacggatc gtcagatcat ctattcgcct cactgtcatg atgacctcgg aatggcagtg
    15061 gcaaatagcc ttgctgctgt caagaatggt gcaggacgtg ttgaagagac tatcaatggt
    15121 attagggagc gagctgaaaa tgctgctttg gaagaaattg cagtggctct caatattcgc
    15181 caagattact accaagtaga aaccagtatt gtcctaaatg agaccatcaa tacgtcagaa
    15241 atggtttctc gcttctctgg tattccagtt cctaaaaaca aagccgtcgt tggtggcaat
    15301 accttctccc acgaatctgg tattcaccaa gatggagtcc ttaaaaatcc tctcacttat
    15361 gagatcatca cacctgaatt ggttggtgtt aagattccgc ttggaaaatt atctggtcgc
    15421 catgcttttg ttgagaaact gagagaattg gccctagatt ttacagaaga ggatatcaaa
    15481 ccactctttg ctaagttcaa ggcactggcc gataagaagt aagaaatcac agatgcagat
    15541 actcgagctt tggtagctgg aaccatggtt gaaaatccag aaggcttcca ctttgatgat
    15601 ttacaacttc aaactcatgc agataatgac attgaagcgc tcgttagcct agccaatatg
    15661 gatggtgaga aagtcgaatt taatgcgaca gggcaaggtt ccgttgaagc aatctttaac
    15721 gctatcgata agttctttaa ccaatctgtt cgtttggtgt cctacactat caatgcggta
    15781 acagatggaa tcgatgccca ggatcgggtt ttggtcactg ttgaaaacag agatacagaa
    15841 accatcttta atgcagcagg gcttgatttt gatgtgttga aggcttctgc tattgcctat
    15901 ataaacgcta atacctttgt tcaaaaagag aatgcaggtg agatgggacg cagtgtttct
    15961 taccacgata tgcctagtgt gtaaaggaga aggctatggc aaagaaaata gtagctctag
    16021 taggagacgg aattggccca gaaatcatgg aggctggttt agaagttctg gaggctctag
    16081 ctgaaaaaac aggttttgac tatgagattg acagacgacc gttcggaggt gcagatattg
    16141 atgcagcagg acctccctta cctgatgaaa cccttaaggc aagtagggaa gcagatgcta
    16201 tcctactagt agctatcggt agtcctcagt atgatggagt agcggttcgc cctgaacaag
    16261 gcctgatggc tctccgtaag aactcaatct ttacgctaat attcgtcctg taaaaatctt
    16321 tgacagtctc aagtatttgt caccactcaa accggaacga atttctggtg tagactttgt
    16381 cgtggtgcgt gaattgacag gcgagattta ctttggagat catattcttg aagagcgcaa
    16441 agcgcgtgat atcaacgact atagctatga ggaagtggag cggattattc gcaaagcctt
    16501 tgaaattgca agaaatcgca gaaaaatcgt tactagtatc gataagcaaa atgttctagc
    16561 gacctcaaaa ctctggcgga aagtagctga ggaagtcgca caggatttct cagatgtaac
    16621 cttggaacac cagctggtag actcagctgc tatgcttatg attaccaatc ctgctaagtt
    16681 tgatgttatt gtaacggaga atctttttgg agatatttta tctgatgaat caagcgtctt
    16741 atctggtaca cttggggtta tgccatcagc cagtcattct gaaaatggac caagtctcta
    16801 tgaacctatt cacggttcag cacctgatat tgcaggtcaa ggaattgcca atcctatttc
    16861 catgatttta tcagttgtca tgatgttgag agatagtttc ggacgttatg aggatacaga
    16921 gcgtatcaaa cgtgctgttg agacaagtct ggcggcagga attttaacga gagatatagg
    16981 aggtcaggct tcaacaaagg aaatgatgga agctattatt gcaaggttat gaagttagac
    17041 gaaaaaatta ctctagtcct tttgatttgg aatgtcatca ttttcttgat ttatggcatt
    17101 gacaaattca aggcaagaag aagagcttgg cgcatcccag agaaaatctt actcatttta
    17161 gcccttactt gtggtggttt tggggcctgg ttagctggaa tcacttttca ccacaagact
    17221 cgaaaatggt actttaaaac agtttggttt cttgggatgg tgaccacact agtagcctta
    17281 tattatattt ggaggtaatg gatggcaggg tcttcgaggg aacacgctgc ttgggctcta
    17341 gcggactatg gttttaaggt cgtgattgca ggatctttcg gtgacattca ttacaataat
    17401 gaactcaata atggcatgtt gccaatcgtt cagcctagag aggttagaga gaaactagcc
    17461 cagttaaaac caaccgacca ggtaactgtg gacttggaac aacaaaaaat catctcacca
    17521 gttgaagaat tcaccttcga gatagatagc aagtggaaac ataaactcct aaatagtttg
    17581 gatgatatcg gtattacctt gcagtatgaa gagttgattg ctgcttatga aaaacaacga
    17641 ccagcctact ggcaggatta gaaaaaatag aaaaggaaat atagtaaact gaaataagat
    17701 gtaaacaaat gaattggagc ttaacatcaa tttccagcaa ttttttagaa actacagtgg
    17761 actattctgg attcaacaca ttataaaatt atgacaaaac acattcacaa gaaggctacg
    17821 acattttaaa aggtgagggc ggatgtatcg tttgccctac taaagttggt tacattatca
    17881 tgaccagcaa caaggcagga cttgagcgta agttcgcagc caaagaacgt aagcgtaaca
    17941 aaccaggtgt tgttctctgc ggtagcatgg atgaactttg cgctttagcg caactcaacc
    18001 cagaaattga agcattctac taaaaacatt gggatgaaga tattcttctt ggttgtatcc
    18061 ttccttggaa accagaagcc tttgaaaaac tcaaagcata cggggatggc cgtgaagaac
    18121 ttatgactga tgtacgtggt actagctgtt ttgttatcaa gtttggaaaa gcaggtgaac
    18181 aattggctgc caagctttgg gaagaaggta aaatggtcta cgcctcatct gcttcaatga
    18241 caaaacgact gaaactcgct atgagcaagg tgtaatggtg tctatggtcg ataaggacgg
    18301 caaactcatc ccagaacaag gaggagcacg ttcaacctca ccagcaccag ttgtgatccg
    18361 taaagggctt gacattgata tagtaaaatg aagtaagatc agcacaaagt aatcaggaca
    18421 gtcaaatcga tttctaacaa tgttttagaa gtagaggtgt actattctag tttcaatcta
    18481 ctataaaatc atgatgcacc tgtcagatac ttttaactca tgggactacc gtcagggtga
    18541 gtattattaa gataaaaaaa gaagtctagt gttatgagat attaaagctc ctaacactgg
    18601 gctttttgtt tagaatttct tttatttttc tataggatat gat
//
LOCUS       DAVKMO010000039        18148 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVKMO010000039 DAVKMO010000000
VERSION     DAVKMO010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18148)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18148)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18148
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.039"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            111..782
                     /gene="sdaAB"
                     /locus_tag="VW361_001490"
     CDS             111..782
                     /gene="sdaAB"
                     /locus_tag="VW361_001490"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU9744507.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            791..1663
                     /gene="sdaAA"
                     /locus_tag="VW361_001491"
     CDS             791..1663
                     /gene="sdaAA"
                     /locus_tag="VW361_001491"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU9744508.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            1685..2317
                     /locus_tag="VW361_001492"
     CDS             1685..2317
                     /locus_tag="VW361_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9744509.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            2367..2444
                     /locus_tag="VW361_001493"
                     /pseudo
     CDS             2367..2444
                     /locus_tag="VW361_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(2800..4650)
                     /locus_tag="VW361_001494"
     CDS             complement(2800..4650)
                     /locus_tag="VW361_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9744510.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(4692..5849)
                     /locus_tag="VW361_001495"
     CDS             complement(4692..5849)
                     /locus_tag="VW361_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9744511.1"
                     /translation="MSSKVSGFQDKNGKVWKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML"
     gene            5907..7073
                     /locus_tag="VW361_001496"
     CDS             5907..7073
                     /locus_tag="VW361_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU9744512.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            7212..7538
                     /locus_tag="VW361_001497"
     CDS             7212..7538
                     /locus_tag="VW361_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9744513.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            7525..8118
                     /locus_tag="VW361_001498"
     CDS             7525..8118
                     /locus_tag="VW361_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU9744514.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVTRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            8111..9022
                     /locus_tag="VW361_001499"
     CDS             8111..9022
                     /locus_tag="VW361_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU9744515.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            9084..10148
                     /locus_tag="VW361_001500"
     CDS             9084..10148
                     /locus_tag="VW361_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744516.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIETPEVGEARTEIEEKKASNSTEEESDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKFETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(10326..11186)
                     /locus_tag="VW361_001501"
     CDS             complement(10326..11186)
                     /locus_tag="VW361_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU9744517.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYESIARLDYAKFLEVLPPSFYHQLDANQIEIQPILG
                     QDFKTLAQEK"
     gene            complement(11461..12447)
                     /locus_tag="VW361_001502"
     CDS             complement(11461..12447)
                     /locus_tag="VW361_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU9744518.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(12719..14194)
                     /locus_tag="VW361_001503"
     CDS             complement(12719..14194)
                     /locus_tag="VW361_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU9744519.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPFDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(14404..15327)
                     /locus_tag="VW361_001504"
     CDS             complement(14404..15327)
                     /locus_tag="VW361_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9744520.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(15341..16270)
                     /locus_tag="VW361_001505"
     CDS             complement(15341..16270)
                     /locus_tag="VW361_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9744521.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(16589..16939)
                     /locus_tag="VW361_001506"
     CDS             complement(16589..16939)
                     /locus_tag="VW361_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744522.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
     gene            complement(17365..17520)
                     /locus_tag="VW361_001507"
                     /pseudo
     CDS             complement(17365..17520)
                     /locus_tag="VW361_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         5423 a         3863 c         3382 g         5480 t
ORIGIN      
        1 atactatttt tatgctattt gaggtattag aaaggttttc atccacaatt aaagccaagc
       61 ccctcattct ttgatataat agagataaga atttttataa ggggaaactg atgaaatcac
      121 ttcgttttca atctgtcttt gatatcatcg gaccagttat gattggccca tctagtagcc
      181 ataccgctgg tgctgttcgt attgggaaga ttgtctcttc catttttgat gatactccga
      241 cagaagttga attccaactt tttaactcat ttgccaagac ctatcgtggt cacggaacag
      301 acctagccct tgttgcaggt attttaggaa tggatacaga tgatcctgaa attccaaata
      361 gtctggaaat tgcccacaag cgtggtatca agattgtctg gaccattcag aaagacagca
      421 atgcccctca ccctaacacc actaaaatta ctgttaaaaa tgcccacaag accatcagcg
      481 tgactggtat ttctatcggt ggaggaaata ttcaagtaac cgaactcaat ggttttgccg
      541 tctctctcaa tatgaataca ccgactatca tcatcgttca tcaagatatt ccaggtatga
      601 ttgcccttgt tacagaggcg ctttcccgct atggtatcaa tatcgcccag atgaatgtca
      661 ctcgtgaaaa agctggtgaa aaagccatta tgattatcga agttgacagt cgcaactgtg
      721 atgaggctat cgaagaaatt cgaaaaatcc ctcatctcca caatgtcaat ttctttaaat
      781 aggaggaagc atgttttatt ctatcaaaga attggtcgag caagcagatc tggactttca
      841 aggaaatgtc gcagaactca tgattacaac agagtttgaa ttgaccggtc gcgaacgtga
      901 agaagtcttc cttctcatgg aacgcaatct ggaagttatg aaagcctctg tccaacttgg
      961 cctcaatgaa aataaatctc gtagtggcct gacaggtgga gatgctgcca aattggacca
     1021 ctacatcaaa aacgaaaaaa ctttatcaga ttacacgatt ctctctgctg cccgaaatgc
     1081 catcgcagtc aatgaacaca atgccaaaat gggcttggtc tgtgctactc ctaccgcagg
     1141 aagtgccggt tgtctccctt ccgttctcac tgctgctatt gaaaaattag acctcagcca
     1201 cgagcaacaa ttggatttcc tctttgctgc tggtgccttt ggactagtca tcgcaaacaa
     1261 tgcctccatc tcaggtgctg agggtgggtg tcaagctgaa gttggttcag cctctgctat
     1321 gagtgctgcc gccttgactc tggctgcagg tggaacacct tatcaggcca gtcaagctat
     1381 tgcctttgtc attaaaaata tgctaggcct catctgtgac cctgttgcag gtttggtcga
     1441 agttccctgt gtcaaacgta atgccatggg agctagcttt gctttcatcg cagcagacat
     1501 ggccttggca ggtatcgaat ctaaaatccc tgtggatgaa gtgatcgatg ccatgtacca
     1561 agtaggagca agcatgccaa ctgcctttcg tgaaacagct gaaggtggac tcgctaccac
     1621 ccctactggt cgtcgcctcc aaaaagaaat tttcggagaa taagcttatc aaataggaga
     1681 aaccatgacc tctatcacag cgattttttt cgatttggat ggaaccctcg ttgatagttc
     1741 tatcgggatt cacaatgcct ttacctatac ctttaaagag ctgggggtgc ctagccctga
     1801 tgccaaaact attcgtggtt ttatgggacc acctctcgaa agtagttttg cgacctgcct
     1861 gtccaaagac caaatttctg aagccgtgca gatatatcgt tcttactata aggcaaaagg
     1921 catctatgaa gctcaactct ttcctcagat tatagacttg cttgaggagt tatcgagcag
     1981 ttatccactc tacatcacca cgacaaagaa tacatctact gctcaagaca tggcaaaaaa
     2041 cttggaaatc catcatttct ttgatggcat ttatggttct agccctgaag caccccataa
     2101 ggcagatgtc attcaccaag ccttgcagac acatcaacta gcaccagaac aagccatcat
     2161 catcggagat accaagtttg atatgctggg agctcgagaa acaggtattc agaaattggc
     2221 cgtcacttgg ggatttggag agcaagcaga tctactaaac tatcaacctg attatatcgc
     2281 tcacaaaccc ttagaggttt tggcgtattt tcaatagcat agactgggta acaattccat
     2341 ttcagaagaa aatgaagtaa tactcaatga aaatcaaaga gcaaactagg aaactagctg
     2401 cgggctgctc taaacactgt tttgaggttg cagatagaac tgacgaagtc agctctaaac
     2461 actgttttga ggttgtagat ggaactgacg aagtcagctc taaacactgt tttaaggttg
     2521 tagatggaac tgacgaagtc agctctaaac actgttttaa ggttgtagat ggaactgacg
     2581 aagtcagctc taaacactgt tttgaggttg tggatagaac tgacgaagtc agctctaaac
     2641 actgttttga ggttgtggat agaactgacg aagtcagtaa ccatatacgg caaggcgacg
     2701 ttgacgtggt ttgaagagat tttcgaagag tataagtctc tacataataa aacgcatagt
     2761 accaaggtta acaaacttga tactatgcgt ttttcttttt tattcaatgt gggttgtttg
     2821 attagcaaag gcgataatag cttgcttcaa ctcatctcca ctgagagtgc ggaactctcc
     2881 aatcttttga ttgatggatt ctaaaggcat gacattaacc ttaccaacga aaatcttatc
     2941 cataacttga ttgtcaacga gttcggttga taccaagagt tcttcgtaga gtttttcacc
     3001 tgggcggatt ccaacttcaa cgattggaat ttcactttca gtgtggccac ttagaagcac
     3061 catcttcttg gccaagtcat aaatcttgac tggtttaccc atatcaagga taaagacttc
     3121 cccatctttg gcataagcac cagcatggat aaccagacgg ctagcttctg gaatggtcat
     3181 aaagtaacgg gtcatgcgga aatctgtcac cgttacaggc ccaccttcag caatctgacg
     3241 ttcaaagact ggaatgacac taccacggct accaagaaca ttcccaaaac gaactgcaca
     3301 gtaggttgat tggctacgtt ggttaaagcc agtgacaatc aactccgcca cgcgcttggt
     3361 tgctcccata acatttggtg gattaactgc cttatctgtc gaaatcataa ccatcttaga
     3421 cactttagct tcatcaacag ccttagcaac attgtaagtt ccacggatat tgtttttgaa
     3481 ggcttctttt ggattgcgct ccatcatagg aacatgcttg tgggctgccg catgataaac
     3541 aatagcaggt ttgtactgct caaagacttg caacaaacga tcatagtctt gaatgtccgc
     3601 aatcacaggt acataatcaa tcccttggaa cttacgaatc aattcatgat aaacaaggta
     3661 gattgagttt tccccatgac cgagcaagac aatgcgttca ggattgaagc gactaacttg
     3721 acgacagatt tcagaaccga ttgaacctcc agctcctgtg actaagatgg tcttacctgt
     3781 cagttctgca cccagacgcg attcgtcaag acggatttcc tgacgaccca aaaggtccgt
     3841 aatatcaatt ttttggaagc cagtacctgc ttggtgaagg ccctgaacaa cagtttcaac
     3901 cttaggcatc ttgtaacatt tgacacccag cttattacac atctgcaaga tacgctcata
     3961 ttctgacgga tccagcgacg gaatcgcaac gatgacacgc tcgatttgat ggcgtttggc
     4021 taattcaggc agattgtcat aagagcccaa aacaggaata ccaccaagtt tttgaccctt
     4081 tttcttagaa tccttatcca aaataccgac cagttctaat tcactggttg gatgttggta
     4141 actatccata aaaagagccc caccatcacc ggcaccaatc aagaaggttc gacggtgttc
     4201 tccatcacca ctaccttttt tgcgtctgga gtagattaac tgccaagtaa tccgtggcaa
     4261 taaaatcaag aaggtactca acaagataaa gagaatgatg aaacggatgg agaagagtgg
     4321 caagaaggca taacagatac tatatgacaa gacactgcta gcagtcacac caaaaaagat
     4381 tttcatgaaa tccgtaatct tgctgtaacg actaatgctc gcgttcaacc cccaaaaacc
     4441 aatcatcaat tgatagaaca ggaaggccaa actcgtatag ataatgtagt caacaggtgc
     4501 tggattaatc agcccataaa ataaaatata agatacaatg atggaaacca ccatactgaa
     4561 aatatcaaat attccccaga aaacctgctt ttgttgttta tttaaaattt ccaccagatc
     4621 aatcacataa tctgttagtt ttttattcat agaaatctac tcctccttaa aagagtttta
     4681 ctatattgtt attatagcat attttgattt atttggctta ttttatccaa ataaattatt
     4741 gttcccttgt actccttctt ccatttaaat cctctaatta aacctacaat cgtcccaaag
     4801 ccataagcaa agtgaatgga aaataaaaga aagggcatca caattagaaa tccattttta
     4861 tgttttaata aagtcagcaa agtgagtagt gacaaaagta gaaaataggc acctaatagt
     4921 aaagttatga atacgaatgt gatcggtaac aatgctagac taaacacaag actcaaaaca
     4981 aataaacaag gaacatagtg aaataatgat aaacacttaa actgaacatg acttgtcaag
     5041 ccaatccaca aaccatttga atacttttga tgcagcattt tcttgaatgt tggtcgaata
     5101 tactgataag atagaatact tgggctatag cggattttat aaccatgttc tcgaattcta
     5161 taatgaatat cattatcttc agttcggcca agttgctcat ttactaaacc aaccttctgg
     5221 aaaacctctc gtttatacat tccatgaaaa atagaagaaa catatctatc ctcagaacta
     5281 tttcgataat tggcaatgct actgccaaac atattttcct caacaagatg caaggtctct
     5341 gcccattttc cttttccttc gacaatcgtc ggtctaggcc ccccacagac aaattcacct
     5401 tgttgaataa tagccacatt gttcattaca aaagtctcag taacttttga atgagcatca
     5461 atttttaaaa taaggtcccc tacagaatgt ttaactccca ggttaaaacc actagcttga
     5521 tttttcttag gattgttata caatctaatt gagttaaact ctgtatcttc ctttataaat
     5581 tgctgaatga tagctgtggt cccatctgtg gacatagcat ttataaatag aatttcaata
     5641 ttctctttag gataagtttg attttttaag tcttcaatta gaccaggcag atatttttct
     5701 tcattgtatg cactgattac aatggatacg agaagacttt caacattttg agtcactact
     5761 actctcctga atttttcctt ccaccattct atcataattt tccagacttt cccattttta
     5821 tcttgaaagc cagaaacctt acttgacatt atagtgaaaa agccttaaaa taagctgtta
     5881 ttaaaatcag ctagaagagg tattatatga aaaagcaatc actctttttt gttccaggta
     5941 ttatcctgat tggtgtttcc ttgcgaactc cttttactgt tttacccatt attttgggaa
     6001 atatttcgca aggtctagag gtagaagtta gttcgcttgg tgtcttgacc agcctgcctc
     6061 tccttatgtt taccctcttt tcaccatttt ctacccaact ggctcagaaa atcggcttgg
     6121 agcatctctt cacctacagc ctcttcttct tgaccatcgg ctcacttatt cgactaatca
     6181 atctgcccct gctctatcta ggaaccttga tggttggggc aagtgtcgca gtcatcaatg
     6241 tcctgcttcc tagtcttatc caagccaatc aaccaaagaa aattggtttt ctgaccacct
     6301 tatatgtaac gtctatgggg attgcaacgg ctctggcttc ctatctagct gtgcccatta
     6361 cacaagccag ttcttggaaa ggacttatcc tcctcctcac gttactctgt ctagcaactt
     6421 ttttggtctg gctcccaaat caccgctata atcatagact agctccacaa accaaacaaa
     6481 aaagtcaaat aaaggtcatg cgtaataaac aggtttgggc aattattatc ttttcaggtt
     6541 ttcaatcctt gatcttttac accgtcatga cctggttacc taccatgtct atccatgcag
     6601 gtctatccag tcacgaagct ggcttgctga cttctatctt atctctgatt agcattcctt
     6661 tttcaatgac catcccaagc ctgacaacca gtttatctac tcgcaaccgt cagctcatgc
     6721 tcactctggt ttcactagct ggtgtggtcg gcatttccat gctctttttc ccaatcaata
     6781 atttcattta ctggcttgcc atccatctcc tcatcggaac cgcaaccagt gccctcttcc
     6841 cttatctcat ggtcaacttt tcactcaaga caagcgcccc tgaaaagaca gcccaattgt
     6901 ccggcctatc tcaaacagga ggctatatcc tagcagcctt tgggccaacc ctctttggtt
     6961 acagttttga cctgttccac tcttgggtac catctgtagc tgccctcttg ctcatcgata
     7021 tcctgatgac tgtggccctc tttacagtgg acagagcgga taagatcctt taaacttcta
     7081 gttttagcta gaagtttttt atatataaaa attttacaca tttctcttga cagggatttc
     7141 ttttagatgt acaatatatg tgtagaaaaa ttatatataa aaatcttaca cattagaaaa
     7201 ggaggtttcc catgtacttt ccaacatcct ctgccttgat tgaatttctc atcttggctg
     7261 tactggagca gggtgattct tatggttatg agattagcca aaccattaag ctgatcgcta
     7321 atatcaaaga atccacactc tatcccattc tcaaaaaatt ggaaggcaat agctttctga
     7381 caacctattc tagagagttc caaggtcgca tgcgcaaata ctactccttg acaaacggtg
     7441 gtatagagca gctcttgacc ctaaaagatg aatggacact ctatacagac accatcaatg
     7501 gcatcataga agggagtatc cgccatgaca agaactgaat acctgactca gctagaactc
     7561 tatctcaaga aactacctga agctgaccgt atcgaagcca tggactattt cagagagctc
     7621 tttgacgatg ctggagtcga aggagaagaa gaactcatcg ctagtttggg aactcccaaa
     7681 gaagcggccc acgaagttct atccaatctt ctcgataaaa aaatcaatga agcacccgct
     7741 caaaaaaata accgacaaat tttacatatc gccttgttag ccctccttgc agcacctatc
     7801 ggcattcctc tgggaatcgc catcctcgtg accctgttcg caatccttgt agccgctttg
     7861 actgtcattc tggctttctt tgcagtttcc atactgggta tcatcggcgg attcctattt
     7921 ttagttgaaa gtttcactgt cctcgcccaa gccaaatcag cctttatctt gatttttggt
     7981 tctggtttac tggctatcgg tgcttcttcg ctagttttac ttggcatttc ctatgtaact
     8041 cgcttcttcg gtctactcat tgttcgtctg gtacaatttg ttcttaaaaa aggaaagaga
     8101 ggtaatcagc atgcgtaaat ggacaaaagg atttctcatc tttggtgtgg tgactaccgt
     8161 tatcggcttt atcctgcttt ttgtaggtat ccaatctgac gggattaaga gcctactttc
     8221 catgtccaaa gaacctgtct atgatagccg tacggaaaag ctaacctttg gcaaggaagt
     8281 cgaaaaccta gaaattactc tccaccaaca cacgctcacc atcacagact ctttcgatga
     8341 tcaaatccac atttcttacc atccatctct ttctgctcac catgatctta tcaccaatca
     8401 gaacgataga actctgagtc tcactgataa gaaactgtct gaaactccgt ttctctcttc
     8461 tggaattggt gggattcttc atatcgcaag tagctactct agtcgttttg aagaagttat
     8521 tctccgacta ccaaaaggga gaactctaaa agggatcaac atctcagcca atcgcggaca
     8581 aaccaccatc ataaatgcta gccttgaaaa tgcgaccctc aatacaaaca gctatatcct
     8641 ccgaattgaa ggaagtcgta tcaaaaacag taaactcaca acgcccaata tcgttaatat
     8701 ctttgataca gttcttacag atagtcagct agagtcaaca gataatcact tccacgctga
     8761 aaatatccaa gtccatggta aggttgaact gactgccaaa gattatctca gaatcatcct
     8821 agaccagaaa gaaagccaac gaattaactg ggacatctca agcaactatg gttctatctt
     8881 ccaattcaca agagaaaagc ctgaatcaag aggtacggaa ttaagcaacc cttacaaaac
     8941 tgaaaaaacc gatgtcaagg atcaactcat tgcgagatct gatgataata ttgatctaat
     9001 atccacacca agcagacgtt gacaaaaacg cttacatctg ctactatgga agcatattta
     9061 tctaaccaaa aggaggttct accatgaaac aagaatggtt tgaaagtaat gattttgtaa
     9121 aaacaacaag caagaacaag cctgaagagc aagctcaaga ggttgcagac aaggctgaag
     9181 aaacgatagc cgatctcgat acaccaattg aaaaaaatac tcagttagag gaggaagtcc
     9241 ctcaagctga agtcgaattg gaaagccagc aagaagagaa aattgaaact cctgaagtcg
     9301 gtgaagcgag aacagaaata gaagaaaaga aggcatctaa ttctactgaa gaagagtcag
     9361 acctttctaa agaaacagaa aaagtcacta tagctgaaga gagccaagaa gctcttcctc
     9421 agcaaaaagc aaccacgaaa gagccacttc ttatcagtaa atctttagaa agtccttata
     9481 tccccgacca agctccaaaa tctagggata aatggaaaga gcaagtgctt gatttttggt
     9541 cttggctagt ggaagcgatc aaatctccta caagtaagtt tgaaacaagt atcacacaca
     9601 gttacacagc ctttctcttg ctcattctgt tttctgcatc ttcctttttc tttagtatct
     9661 atcacatcaa acatgcttac tatggacata tagcaagcat taacagtcgc ttccctgagc
     9721 agctagctcc tttaactctt ttttctatca tctctatcct agtagcgaca acactcttct
     9781 tcttttcatt cctcttgggt agtttcgttg tgagacgatt tatccaccag gaaaaggact
     9841 ggacgctaga caaggttctc caacaatata gtcaactctt ggcaattcca atcttcctca
     9901 ctgctattgc tagtttcttt gctttctttg atagcctacg atttacagcc ctcttgtgtg
     9961 tgattagcat tggaatcatt ctgcttgcca gtctccatat cattacaaga ccaagtcaag
    10021 caagtgaaac cgactccttc tatcaattat tcttgtctgt ccttgtgaac ggagttatta
    10081 tcctcctctt ctttgtagct gaagtggcac tgattggaga ttatcttcgt atcttggcct
    10141 ttctttaaaa ttcatactct tcgaaaatca aattcaaacc acgtcagctt cgccttaccg
    10201 tactcaagta cagcctgcgg ctagcttcct agtttgctct ttgattttca ttgagtagca
    10261 atcctgtcat ccttggcagg attttttcta tgtcaaaaaa gcaagtcgat tgacctgctt
    10321 ctgctttact tttcttgtgc taatgtttta aaatcttgtc ctaggatggg ttgtatttct
    10381 atttgattgg cgtctagttg gtggtaaaaa gatgggggta atacctctaa gaattttgca
    10441 tagtccaagc gagctatgga ttcatagtct tctggtttag agccgtctcc tgtgatttga
    10501 accaagtcaa tctcccactg gacttcctta tccaccaatt gctcaatata ggctgcagga
    10561 acaaacggtt ctctcggtaa aactgtcttg actccttgag ctagatggta aacgccatgc
    10621 acttttcctt ctccatcctg atagaaggaa actctcgcaa agtaggcatc tgtctcttga
    10681 accgcacgca cacgcgcttc aaactgagcc aagccatctg cctctaaaaa gcttttcaag
    10741 ttctcacgac taaagaaaat aggattaaaa attccttggc aaatcgtaaa acgagctaca
    10801 gggtctgcta gataggcttg aatacttgct tggaaataag cttcaaaatc aaaaccatct
    10861 agcccttcaa tatcagtccc tgtataagca agcaaagcat ctaaaaatga cttgataatc
    10921 tgccagtctg tctttgttag taggtcagga agatcgacac ggtaagcctt ttgaccatca
    10981 gcataactga ccttaaaaag aaattgtgat tgccccacta tcgcacactc aatatactcg
    11041 agacgattaa gaggctgacg gagatagact acatcatagc tatgtgactc caaaccgtct
    11101 agcaaggcca agatcgactt ggcattcaaa atctcttgtt ctcctaaaat gctctgttta
    11161 tttggaataa aaaatgtttt tgccataact ggactccttt gaaatcgttt acatacagta
    11221 taccttattt ttctgaaaga tacagaaaca aactttatac tcttcgaaaa tctcttcaaa
    11281 ccgcgtcagc ttcgccttgc cgtagatata tgtaactgac ttcgtcagtc ttatctacaa
    11341 cctcaaagca gtgctttgag cagcctgcag ctagcttcct agtttgctct ttgattttca
    11401 ttgagtatta gatttttgag tacaaagcat agaaaaacag cccctgagga ctgtttgatc
    11461 ttatacagta gctgcttgat ccaagctttc accgatagcg gctaggcgct cgatcacttc
    11521 agcttgtgtc aattcatttt ttgaaacata gcggttacgt gggtgaacac ggcactcgtg
    11581 tgagcatcca cgaaggtact tgtcttcatt ttcttccgat gtcaagatac gacggttaca
    11641 gaatggattt ccacagttga cataacgttc acatggtgtt ccatcaaacc agtctttccc
    11701 tacgatagtt gggttgacat ggttgacatc aacggcaata cgctcgtcaa agacgtacat
    11761 tttcccatcc caaagctcac cttgaacttc tgggtcttta ccgtaagttg cgattcctcc
    11821 gtgcaattgg ccgacatctt tgtagccttc acggaccatc cagcctgaga atttctcaca
    11881 gcgaacgcca cctgtacagt aaaccacgac acgcttgtcc atgaattttt ccttgttatc
    11941 acggacccat tgtggtaact cacggaagtt gcgaatatct gggcgaatag ccccacggaa
    12001 atgtcctaga tcgtactcat aatcgttacg tgtgtcaagg acaacggtat ctttatcaag
    12061 aagcgcttct ttgaactctt ttggagacaa gtaagcacct gttgtttcaa gtgggttgat
    12121 gtcattgtca aagtcgttgt cttccaaacc aaggtggaca atttctttct tgtagcgaac
    12181 aaacatcttc ttgaaggctt gttcattttc ttcgtcaatc ttgaaccaga gatcttccat
    12241 acctgggagg ctgtgaacgt agtccatgta tttttgagtt gtttcatagt cacctgaaac
    12301 tgttccgtta attccctcat cagcgactag gatacggcct ttaaggccga ttgatttaca
    12361 gaaagccaag tggtctgcag caaattgctc tgcattttca attggagtat aaaggtagta
    12421 aagtaagaca cgaatatctt ttgccataag atttgttctc ttttctattc ttaaattttc
    12481 taaatttttt atttatctac actagtatac ctgcttgaga aaacgaatgc aatttatttg
    12541 actggaaatt gtagagggtt ctcgaaattt cctgaatggt taaaataagg acaagagaaa
    12601 acatggatat ctatatcctt gtgccaaaaa aaccactgcc ctccccagac caacctgagg
    12661 aaagcagtga ttcttatttt aggagttagg aatgaataca cgaaatcaat ttagctgatt
    12721 attttttgtt tttcaagaat tcatcgtatt gtttttgcat ttcgttcaat actttttcgt
    12781 aggcaccttc agatttcaat ttttccatca attctggaat cgctttatct gggtctacag
    12841 taccagtgtt gatagctgta tcaaattgtt gcattgtgtt agcaatagct gagatttcag
    12901 atttcacatt gtcagtatta aagataaatc caagcgctgg agattcttta gcttctgcca
    12961 attctttctt agaattttcg atttgttggt ctgtaacgtt ttcgttgatg taaaggatcc
    13021 agttgttacc agtgttccat ccacccatgt gagtgtttcc tttgtagcca tcaagaacgc
    13081 gaacacggtt ttctttacct tcaatttttt cccagttctt gccttctgga ccgtaaacaa
    13141 gaccgttcaa gagttctggg ttggtattca agaggttcaa gatttccatt gatttttctt
    13201 tgttcttaga gttgtttgag atgacaaagt tagcaacttg tgttgtttgg tttttcttga
    13261 tgaagttagt aattggtttg atttggatat ctttgttggc aacacgtgaa agcaagctgt
    13321 taccgtagtc agctggtcct actgtttctt cacgaacgaa ccaagtatct tgttgaaggt
    13381 caaaggaagt atcgcttgtt gcgacgtctt ttggaatgta gccagcttca tagaatttgt
    13441 gaagagtctt caagtgttct ttgaaacgag gcacttcgta acggtttaca actttagtag
    13501 tatcgccttc aaggtcgata acgaatggaa gaccgtttgc tactgggtag tcaaagttat
    13561 caaatgggat gaaaacttta ccaatagcaa atggtactac gtctggagct ttttctttaa
    13621 tttgtttcaa gactggctca agagtttcgt aagaagtaac acctgaaata tcgataccat
    13681 atttagcaag gagagttccg ttgaaggcaa agttttgaga tgacgcaacg ttggctgcaa
    13741 ctggtacagc ataaatctta ccatttacag tattaccctt gatataagct gggtcaagtg
    13801 ccttgtaaag gtctttacct tcttttttgt acaattctgt caagtcagca taagcacctt
    13861 tttgagcatt tacaatatag ttatctgcaa aggcgatatc atagttttca ccagatgatg
    13921 tgataactga cattttctta ccatagtcac cccagccaag gtattggata tccaatttag
    13981 caccaacttt ttcttcgatg attttgttgg catttgctaa caattcatcc aagttatctg
    14041 gtttgtcacc gatttggtac attttgataa caggtttgtc acctgaatca gcagcttttt
    14101 tactgttacc tgtcaagttg ccacaagcag caagacctgc agccaaagcg actacactag
    14161 cagatgcaaa agcatatttt ttccagtttt tcatgataaa aactcctttt tttattttta
    14221 aacttataaa caatgtaatg atcttatact caatgaaaat caaagagcaa actagaaaac
    14281 tagccgcagg ctgtacttga gtacggcaag gcgacgttga cgcggtttga atttgatttt
    14341 cgaagagtat taacttcaca caagggaagt tgggaactga gaaatgttct ttttcaataa
    14401 gcactattct ttcacaccac cgatagtcaa accttttaca aagtagcgtt ggaagaatgg
    14461 atacaaaatc gcgattggaa gggttgctac cacaaccatg gccatacgac ctgtttcttt
    14521 cggtagagca actcccagtt gaccagtcaa gccgaccgct ttggcaatgt agtccatatt
    14581 ttgttggatt tgcatgagca aatattgcaa tggatacaag ttatcactct tgatgtaaag
    14641 aagggcgttg aaccagtcat tccagaaacc aagagctgtc aaaagcgtga tggttgcgat
    14701 acctggtagt gacaatggca aacagatttg gaagaaaatc cgagcctcac tggcaccatc
    14761 gatacgagcc gattcgagaa tggcttctgg aatggtcttc ttgaaaaaag aacgcatcaa
    14821 gatgatattg aatggtgaga gaagcattgg aacaatcaag gcccaaacag tgtcaccaag
    14881 ctgaagtaca cgggtcacca tgatataacc tggtaccaaa ccagcgttga acaacatact
    14941 gagaaggacg aagatggtaa aaaatctgcg atacttaaag gttgtccgtg aaatagcgta
    15001 ggcataggtt gttgtgataa agacatttgt caatgtccca actacggtta caaagacaga
    15061 gatgaagagg gcttgtagga ttttatcctt aaactgtgcc aaaaactcaa aaccgtctaa
    15121 gccaaattgg gatgggaaga agctatagcc gtattggagg aggcttttct cgtctgtcac
    15181 tgaaataatg ataacgaata caaaaggtag gatacaagag agggcaatca aacccgaaat
    15241 gatactgaag aagatatctg ctttcttact gaaggagtga atgccgacat tatcaatttt
    15301 ttctttttta attttctttt ttgccatatt ctcctccttt ctagaacaaa gctgagtttg
    15361 gatcgactcg tcttgcaagc aagtttgata ggataaccag aatcaaacca acaacggatt
    15421 ggtaaagacc ggctgctgca gccataccga tatctgctgt ctgagtcaaa ccattaaaga
    15481 catatacgtc caaaacgttg gttacattgt aaagctgacc agcattgtgt gggatttgat
    15541 agaagagacc gaaatctgcg cggaagatat ttccgactgc aaggatggtc aatacagtta
    15601 caagcggagt caactgagga atggttacgt tgcgaatacg ttgccacttg ctagctccgt
    15661 ccactgtcgc tgcttcgtag taggttggat caattcccat gatcgtcgca tagtacatga
    15721 cactgctata tccaaagcct ttccaaatac ctaggaaaag taggagatag ggccagatgc
    15781 ccaggtcagc gtagaaattg acttctttga gaccaagact ttccaataga tgattgaaca
    15841 cccctttatc aatatttagg aaggcatctg taaagaaact aatgataacc caagacaaga
    15901 agtaagggaa caacatagaa gtttgaaaaa tcttcaccat tctcttagaa cggagctcgc
    15961 tgaggataat ggcaatccct acagatacaa ctaaacctag aaagataaag ccaagattgt
    16021 agaggacagt atttcgtgtg ataataaagg cgtctcttga actaaataag aatctgaaat
    16081 tatcgagtcc gacccattta ctatttatga tactatctat gaaaccatta ctggtcatgt
    16141 ggtagtcttt gaaggcaacc acgttcccaa atactggaat gtaaaagaat agaatcaacc
    16201 agagtgcccc tggcaaaacc atcaagagaa agatccagtt gtctctcaat gtttttgaaa
    16261 actttttcat aatttcctcc ctttttattt tgatatccat ctaaaaattc ttttttagac
    16321 ttttgataac gattacatta ttagtatact cctatttgca ggttaggtta aactcctaat
    16381 tatagaaaaa actccacaaa ttatgtagca gatttaaaac tttatcacca ctatcaaaca
    16441 aatgtcctaa atcaattgtt tattttatct ctattagccc agtgatggcg tcactctgtt
    16501 ataagcatcc aacaacgggg tatactgaaa aatctccaga ctagggaact cagcgatagt
    16561 tcctaatctg gagattttta atatgttatt aggcgtttgc tttcaactta gcaataacct
    16621 ctttaagatt atcaatcaac tctgcttcag tatgctcaga gcctttttca tctgccaaga
    16681 acaaaactgc tttttgaagt tcttcttgag agttttcaag gacatcctta tctgctgttt
    16741 ctttgcccgc tgtttgtcct ccatccttag ttgctgactg gctttcctta atggactcta
    16801 gggaagcaat ggcatctttg actgtttgca agatatcacg taaaccttgc tctgtcaaac
    16861 tatcatctgc aaaagctttc ttagcctctg ccaaaaccag acgtgctgaa tctgtggtag
    16921 gattcgatac acctgtcaat gatctcaaaa gattttctaa ggtttgagtc tgcttactaa
    16981 tactagacta aaataaaaaa gcattatata acagtgatat gaaatcaact aaagaagaaa
    17041 tccaaaccat caaaacactt ttaaaagact ctcgtacagc taaatatcat aaacgccttc
    17101 aaatcgttct atagtaaaat gaaacaagaa caggacaaat cgatcaggac agtcaaatcg
    17161 atttctaaca atgttttaga agcagaggtg tactattcta gtttcaatcc attatatttc
    17221 gtctgatggg caaatcttat aaagagatta tagagctttt atagtagttt gaaataagat
    17281 gtgaacaact ctatcaggaa agtcaaatta atttatagaa atattttagc agccaaggtg
    17341 tactgttata gattcaatac actatacttg gtggtttagc tctcctgttt tctcttttag
    17401 ctttaaccag ccataaatgg tattacgtga gatttggaaa acgtgtgatg cttctgttat
    17461 actacctgtt cgctcacaat aagagagaac ttttttacga aaatctattg aatatgccat
    17521 aaaaggatta taccacattg tgtactattt ttggttcatt ttactatatc actttggact
    17581 atatcggtct agttatgtct caacgattat agctggatac taagagaaat caaaaaagca
    17641 ctctaggata gaggcctaaa gtgcttagtt tcaaggcttt acagcctatc atatttaata
    17701 aaatattaca acattttgtt gtatcgcttt tttaagtatt cagcaagtag ctttattact
    17761 tcttaatgct tgataatagg gtgatgggga gttttcactt ttcgtttgaa cgttttggag
    17821 tttctccctt actccacaaa tcactgaaca tgataaacga gttcagcagg caagaaacta
    17881 gcactattta aaagtgcttt tttgtttcta tttaatagga agctattgca catcttttaa
    17941 tatttgtttt attagtttgc atgaagcatt ctaaatactc ttcatcttct aatctaaaat
    18001 ctaacaatag cataaattta atttcgtatc tgttctgtta tattggaact ctatatgtac
    18061 ctgttcttta atcttcaaag tttagcttag attctttttt gattgtaagt ttagtatttt
    18121 aaaactgtgt ttttccttct tctttaat
//
LOCUS       DAVKMO010000040        18147 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVKMO010000040 DAVKMO010000000
VERSION     DAVKMO010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18147
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.040"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            102..398
                     /locus_tag="VW361_001508"
     CDS             102..398
                     /locus_tag="VW361_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU9744523.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYKDVIDSNGASIG"
     gene            519..1463
                     /gene="manA"
                     /locus_tag="VW361_001509"
     CDS             519..1463
                     /gene="manA"
                     /locus_tag="VW361_001509"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU9744524.1"
                     /translation="MSEPLFLQSVMQEKIWGGAKLRDEFGYDIPSEKIGEYWAISAHP
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADDLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1503..2838)
                     /locus_tag="VW361_001510"
                     /pseudo
     CDS             complement(1503..2838)
                     /locus_tag="VW361_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3044..3798
                     /locus_tag="VW361_001511"
                     /pseudo
     CDS             3044..3798
                     /locus_tag="VW361_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
     gene            complement(3818..4273)
                     /locus_tag="VW361_001512"
     CDS             complement(3818..4273)
                     /locus_tag="VW361_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9744525.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4293..5468)
                     /locus_tag="VW361_001513"
     CDS             complement(4293..5468)
                     /locus_tag="VW361_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9744526.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5527..6372)
                     /locus_tag="VW361_001514"
     CDS             complement(5527..6372)
                     /locus_tag="VW361_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9744527.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6497..7054
                     /locus_tag="VW361_001515"
     CDS             6497..7054
                     /locus_tag="VW361_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9744528.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7073..7540
                     /locus_tag="VW361_001516"
     CDS             7073..7540
                     /locus_tag="VW361_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU9744529.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7629..8258
                     /gene="upp"
                     /locus_tag="VW361_001517"
     CDS             7629..8258
                     /gene="upp"
                     /locus_tag="VW361_001517"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU9744530.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLNLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8432..9022
                     /gene="clpP"
                     /locus_tag="VW361_001518"
     CDS             8432..9022
                     /gene="clpP"
                     /locus_tag="VW361_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU9744531.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9101..9349
                     /locus_tag="VW361_001519"
     CDS             9101..9349
                     /locus_tag="VW361_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU9744532.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9451..10611
                     /locus_tag="VW361_001520"
     CDS             9451..10611
                     /locus_tag="VW361_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9744533.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10879..11748
                     /locus_tag="VW361_001521"
     CDS             10879..11748
                     /locus_tag="VW361_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9744534.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11752..12708
                     /locus_tag="VW361_001522"
     CDS             11752..12708
                     /locus_tag="VW361_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9744535.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12708..13472
                     /locus_tag="VW361_001523"
     CDS             12708..13472
                     /locus_tag="VW361_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744536.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13472..14182
                     /locus_tag="VW361_001524"
     CDS             13472..14182
                     /locus_tag="VW361_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744537.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVASGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14490..15146
                     /locus_tag="VW361_001525"
     CDS             14490..15146
                     /locus_tag="VW361_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9744538.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15254..16349
                     /gene="prfB"
                     /locus_tag="VW361_001526"
     CDS             join(15254..15325,15327..16349)
                     /gene="prfB"
                     /locus_tag="VW361_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU9744539.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQEKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16367..17059
                     /gene="ftsE"
                     /locus_tag="VW361_001527"
     CDS             16367..17059
                     /gene="ftsE"
                     /locus_tag="VW361_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU9744540.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDIPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17052..17978
                     /locus_tag="VW361_001528"
     CDS             17052..17978
                     /locus_tag="VW361_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9744541.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
BASE COUNT         5573 a         3433 c         3947 g         5194 t
ORIGIN      
        1 ttttgatggc ttggatttct tctttagttg atttcatatc actattatat aatgcttttt
       61 gattttagtt tagtattatc gtagaaaatg gactaggtgc tatggataca ccggatgaga
      121 atggttatgt agcagatgac tatcggatta cttacttaga ggcccacatc aaggccatgc
      181 gagatgccat ttaccaagac ggggttgact tgcttggtta tacgacttgg ggctgtatcg
      241 atccagtttc agctggcaca ggggaaatga ataagcgcta tggctttatc tatgtagatc
      301 gagataatgt aggaaacgga gctctcaaac gtagcaagaa gaagtccttc tattggtaca
      361 aggatgtcat tgatagcaat ggtgcaagca tcgggtagag cacatttgtt tactattttt
      421 ataaaatctt ctccctgctt tataagatgt aaaaaagagt tcaattcgaa ctcttttttt
      481 gctataatga ggggagaaaa atcagacagg agatcgacat gtcagaacca ttatttttac
      541 aatcagttat gcaagaaaaa atctggggtg gagccaagct acgtgatgag tttggctacg
      601 acatcccaag tgaaaaaatc ggagaatatt gggccatctc agcccatcca aatggagtct
      661 ctaaagttgc aaatggtcgt tacgagggaa cagatcttgc tactttgtat gcggaacacc
      721 gtgaattatt tggcaatcgt ccagaacctg tatttccact tttgaccaag atcctcgatg
      781 ccaacgactg gctcagtgtc caagttcacc cagacgatgc ttatggactc gagcatgaag
      841 gcgaactcgg aaaaacagaa tgctggtaca ttatcgcagc ggatgaaggt tcagagatta
      901 tctacggtca caatgccaag tcaaaagaag aactccgcca gcaaatcgag gacaagaact
      961 gggatgactt gttgaccaaa gtccctgtta aggctggaga tttcttctat gtaccaagcg
     1021 ggactatgca cgctatcggg gcgggtatct taatccttga aacccagcag tctagcgata
     1081 ccacctatcg cgtctatgac tttgaccgca aggatgacaa aggcaacttg cgtgaacttc
     1141 atcttgaaaa atccatcgat gtcttgaaca ttggtgagcc agcaaatagc cgtcctgtaa
     1201 ctgttaaagc agatgatttg cgttccactc tccttgtatc taatgatttc ttcgcagttt
     1261 acaagtggga aattactgga aaagttgact ttgaaaagac agctgactac agtttattga
     1321 gtgtcttagc tggtcaaggt cagctaactg ttgacgggaa aaattatcca attcaaaaag
     1381 gcagccactt tatcctacca agtgatgttg aagcttggac tctggaaggg caaggtttgg
     1441 aattgattgt tagccatcca taaaaagaaa gggcctgagt tcactactca agttcttttt
     1501 gattacataa attgggcaat gaagaccaca atgatgatga ttggaatgac gaaacgaaga
     1561 aacgaagaag gaagagccag acttggaaca gtccttgttt ccatgctctt tcatcgagat
     1621 ggagttcctc cattgcaaga gcctttttaa agatatagcc tgtaaaaagt gaaaggtaga
     1681 gagctccaaa tggcatgagg agattggaaa ccaagaagtc catagcgtca aagaaggtct
     1741 taccaaaaat gtgaacatcc gccatgacac cgtaagatag ggctgaagga atgccaaaga
     1801 caaaggtcaa aattcctaaa ataacactcc atttggcacg tttgctgtta tcctggttgg
     1861 tgacattgcc cacattgatc tccagcatca cgacagaaga agtgacagtc gcaaagagga
     1921 agaggacgta gaaaatggtt ccaaaaggca tcttgtcaaa gagttgaggc aagacgataa
     1981 agagcaggct gggtccccct tcagactgga tattgaaggc tgacatggct gggaaaatgg
     2041 ctagacctgc catgatggat atcgagatat tcatggctac gatggagatt cctgactgga
     2101 ctagattggt tttcttgtcc aagtaagaag cataggtcaa catgactgta acccctagtg
     2161 agagggcaaa gaaagattgt cccagagcat agaggagatc agcgctagtc agttttgaaa
     2221 agtctggttt gaggaagtaa agaacccctt ccatggcatt tgacaagctg agagagtgac
     2281 cgatgataac aacaaagatg ataaagagca ggggcatcat gactttcgaa gctctttcaa
     2341 tccctttttg aaccccacgt gatacaatga agatattcaa taggataaag gacgcttgag
     2401 ctcctagggc aatggctgga tttgaaatga ttgaagtaaa taactgagca taatcacccg
     2461 ttccaccaag ttggaacaat ttcccaaact caatacctag atagactaga atccatcctc
     2521 cgataacact gtaaaaagat aagaggataa agagggcaaa ggcgccaatc caaccgataa
     2581 agttgtactt gttattcttg cccagttttc caaaggtttt gatagcggaa acgccagcac
     2641 tacggccaag ggcaaactca gccagcagga gagggaaacc gattaaaata gtggaaatga
     2701 gaaagattag taaaaagcct ccatcgccat tagcagcagt catgtaggga aacttccaaa
     2761 cggaaccaag cccgatggcc agccagcaga tgctagaata aaaccaagtt tcgaccccca
     2821 ttgtgatttt tctgacatag ttaaactctg atctcctttt tcaaaataag aaaaagctac
     2881 ttgagttgtc aaatagcctt ctgtttgatt gatagacttg actatcctat tatgttttct
     2941 aaggtctgtc aagcaaacca ttttcaagtt ttcacacctt tctcaaaaac gcttgactct
     3001 gacctaaggg gaggggttat actatcattg taaggaggaa atcatgtacc atataaaaga
     3061 agctgcgcag ctttcaggtg tctctgtcaa gaccctgccc tgcatcacta tgacaagata
     3121 ggactcttgg tccccttaaa gtcggaaaac ggctatcgaa cctatagtca agaggatttg
     3181 gaacgccttc aggtcattct ttactacaaa tatctaggct tttctttaga gaaaatagca
     3241 gagctgttaa aggaagaaag gacagattta ttgccccatt taactaggca gttggactat
     3301 ctaactcgcg aaaggcaaca tctggatacc ttgatttcca ccttgcaaaa aactattcaa
     3361 gaacaaaaag gagaaagaaa aatgaccatt gaggaaaaat tcacgggatt tagctatcaa
     3421 gacaatcaaa aataccacca agaagcggta gagaaatatg gtcaagaagt catgggacaa
     3481 gcgcttgaac gccaaaaagg tcacgaaaac gaggctacgg ccgcctttaa ccaagtcttt
     3541 caaactttgg cacaaaatct tcaagctggt ttacctgcaa cagcaaccga aaaccaagag
     3601 caagcagcca agctcttgca agccattcgc acttatggat ttgactgctc tattgaggta
     3661 ttcggtcata tcggtaaagg ttacgtctac aacccagagt ttaaggaaaa cattgacaag
     3721 tttggttctg gaacagccca gtacacgtca gatgccattg cggcttacgt tcagacaaat
     3781 gcagaaaaaa taggctagga atttcctagc ctatttttta cttcaaatca taaagccagt
     3841 cgtcaccgtt tttgtagtaa aagaattcac tgagatcttc ttctagaaac acacgaagca
     3901 tatcagacat atcatcggtt gcaagtttta gatgagaaag attttcaaag tcctcccacc
     3961 aaactttccc ttcgtctgaa gactggagtt caccagtaaa gtgttctgtc ttgtaaaaaa
     4021 ggacgacata acgataatcc ttgtcgtcat accagttttt gataccacag agttggggtt
     4081 tggaaatgat cagaccagtt tcttctttca cttcacgaat gacagcatcg acaaaggatt
     4141 cgccacgttc aacatgacca ccaggaaaag taatgccaga ccagtcggga ctaactcggt
     4201 cttggaccag gaccttatct ccgtttttaa tcatacacat gttaacaaat tcgactgcct
     4261 ctcttctgtt cattcttcac aacctttaat ctttaatcat aatgcagact tcccgccacc
     4321 cagccggtac agagggcaga agtgatgtta aagccacccg tgtgggcatt gatatccata
     4381 acttcgcctg caaagtggag gccaggtacc agcttacttt caagggtttt aggattgatt
     4441 tccttgagac tgactccacc cttggtaaca aaggactttg caagggacat ttttccagtt
     4501 acaggaattt taagttcttt aatggactgg acaagttgtt ctcgttcctt ttcagtcagc
     4561 tgtttgactt tttcaggata tccttgtaca aaaaattcgg ccaagcgttc tggtaacaag
     4621 gtttttaaag cgtttttcaa ggatttttcc cgattttctt ctagaaatgt aaccaagtcc
     4681 ttctcagaaa gttgaggcaa aacatcgagt gagagaacct ccccaccttt gacaaagcta
     4741 gacatgcgta gggcagcagg acctgacaaa ccaaagtggg taaagagtaa atcatgagtg
     4801 atgacatgct taccataact tagggtcaca tcgtccaaag aaatcccttg taaggcttta
     4861 tgtggaaaat ctgttaataa aggactttca gcagcctcaa gctcggtgat ggtatgctta
     4921 aaatggcgag caatctcgtg accaaaacca gtcgaaccag tcgaaggata agacttacca
     4981 cctgttgtga caatgagttt ctcacaagtg aaggtttgat ccgctgactt aaggacaaac
     5041 tggtcatcta cttttttaac agaaacgatt tctatttgag tagcaacttg accacctagt
     5101 tcagtgattt tcttttccaa agcttcgata atagtccgag acttgtcact ggctggaaag
     5161 acgcgtccgt ggtcttcgac cttaagttta acaccatttt ctgtaaaaaa gttgatgatg
     5221 tcatgattat cgaactggga gaaaacactg taaagaaagc gtccgtttcc aggaattcca
     5281 gctagcaggt tgtctaagct accattgttg gtcacattgc aacgtccccc accagtccca
     5341 gctaattttt ttccaagttt ccgatttttt tcgatgagga gggttttctg tccataaaag
     5401 ctactggaaa tcgtagccat cataccagca ggtcccccac cgatgacaat agtatcaaaa
     5461 tgtttcatag ctctattgta ccacaaaaaa acaagagatg atggtcacct cttgtcaaga
     5521 atgcaattaa tcaatttcat agcccatcag caaaccgccc tcttctgcat agaaactgca
     5581 gagaccagag gttggtagaa ttttaatatc cgcttgtggg aaggtttcac ggattcgctc
     5641 tgagagctgt tgacaacatt tttcgttatt gcgttgggcc atgacaatac ggccaccagc
     5701 atatccagct tttactaact catcataggc agcttgaact gatttctttg atccccttgc
     5761 tttttgtagc aattcgagag ttccagtttc actagctttt ccgaccatac gaatgttgag
     5821 aaggccaacg accgtaccga taagcttgct caaacggccg ttcttcacca agttatcgac
     5881 tttggctagg acaaagagca acttagtttt ttcttgatag gcggtgatag cttcaaccac
     5941 ttcttcaaaa gacaagccct ggtcaatcaa gtcattcaat ttttctacga gtaggtcaac
     6001 ttcaccacca gcagataaac tatcaatcac atgaatctta gtgtcaggat ggtcttccag
     6061 ataaatattc tttgctagtt gagcactatt gtgactacca gaaagggtac ctgtgatggt
     6121 tactaggaaa atgtttttgg caccttcaaa tgctcgcaaa tagtcatctg ggcttggaca
     6181 agccgatttt gaagcttctg cagttgcata catggtttcc atcatttggt caatatcgag
     6241 actggcgtca tcaacaaaga cctgatcagc tacttgaatg gttaagggga cacttacaaa
     6301 ggttgtgtta atagctggtg ttggcagttg acgataatca caaccagagt cagcaataat
     6361 cttccaagtc atagaaattc tccatctttg tcagttatac attgacaaag gttctgtctt
     6421 tttttacaat tatatcatga aaacccttga aacaaaagca tcatccgtct gttgtgacaa
     6481 gtagaaagaa aatgttatgt ctgaacgtag aatctctgaa aagtctcttg aaaatctcag
     6541 aaaatcaaac caagaatcca atttattaac cagagaagcc attgaaacag ccctcttgca
     6601 actcttggaa aaaaaggaac tgaccaagat tagtatttct gaattggtca aacgtgcagg
     6661 tgtttcgcgt gcggcctttt atcgcaatta tgactccaaa gaggaaattt tagagagcgt
     6721 ctttaaacga actgtccaca atattatgga acagctgcat cattacgatt taaagacaga
     6781 cctttatttg gtttgggttc accttttccg ggaggccaga aaggaagcta gagtaattca
     6841 attggccttg gattaccatc tggaaaaaat ctttgtccaa gccatgcagg aatttctaga
     6901 aaaataccat gggaaatcaa aaggtgtcag ctcttatctt cattccttct ggagctcagc
     6961 catcgtctct gtccttctaa aatggatcaa ggatggcatg aaggtaccag ctgaaaagat
     7021 tgcagattta ggtttaccat tttttaaaaa atagagaaaa aggagaaaag agatgactga
     7081 aaaaagactg gcctgggatg agtattttgc agcccaagcc ctactaattg cgaatcgttc
     7141 cacttgtaaa cgtgctaaag tgggcgcgat tctggtaaaa gataataagg ttatttccac
     7201 tggttacaat ggttcggtgt cagggactga gcattgtatt gatcacgaat gtttggtcat
     7261 tgaaggccac tgtgttcgca cccttcacgc tgaggtcaat gctatccttc aaggtgctga
     7321 gcgtggtgtt cccaaaggct ttacagccta tgtaacccat tttccttgtc tcaactgtac
     7381 aaaacaattg cttcaggtcg gctgcaagcg tgtggtttat atcaaccagt accgaatgga
     7441 cgactacgcc caataccttt atcaagaaaa agggacagaa ttgacccatt taccacttga
     7501 gacagtacag acagctctta aagaggctga tctaatgtaa aaattatcaa aaataaatgg
     7561 tttagaaaga tttttaaacc gttttttggt ataataagaa gaataaattg aaagaaggaa
     7621 ttccaaaaat gggaaaaatt gaagttatta atcacccact gattcaacac aaattgtcaa
     7681 tcttgcgtcg tacagatact tctacaaaag cttttcgtga gctagtagat gagattgcaa
     7741 tgttgatggg gtatgaagta cttcgtgatc ttccactaga agatgtggaa atcgaaacac
     7801 caattacaaa aacagttcaa aaacaattgg caggtaagaa attggccatc gtcccaatct
     7861 tgcgtgcagg tatcgggatg gttgatggtc tcttgaactt ggttccagct gctaaagttg
     7921 gccacatcgg tatgtaccgt gatgaagaaa cacttcaacc agttgaatac ttggtgaaat
     7981 tacctgagga cattgaccaa cgtcaaattt ttgtagtaga cccaatgttg gcaacaggtg
     8041 gctcagcaat cttggctgtt gattctctta aaaaacgtgg cgcatcaaat atcaaatttg
     8101 tctgccttgt atctgctcca gagggtgtaa aagcccttca agaagctcat ccagatgtag
     8161 aaatctttac agcagccttg gatgaacgtt tgaacgaaca cggttatatc gttccaggtc
     8221 ttggagatgc tggagaccgc ttgttcggta caaaataaga tcgaaaagaa gaatgacttg
     8281 gaaaagtatt tccagtcacg aaaggaggtt gggtttttgt ttctgtctaa tgaaagcaga
     8341 gcaaaaattt gacctttttt gaccaagata ttataatagt cttatcttca gtcatttgac
     8401 caacaaaatt aaaactcaaa aggagaaatg aatgattcct gtagttattg aacaaacaag
     8461 ccgtggagaa cgttcttacg atatttactc acgtcttctc aaagaccgca tcattatgct
     8521 gacaggtccg gttgaagaca atatggctaa ctctgttatt gcccaattgc ttttcttgga
     8581 tgcccaagat agtacaaaag atatttacct ttatgtcaat acaccaggtg gttctgtttc
     8641 agctggtttg gcaatcgtag ataccatgaa ctttatcaag gcagatgtcc aaaccattgt
     8701 tatgggaatg gctgcatcta tgggaacagt catcgcatca agtggagcaa aaggcaaacg
     8761 tttcatgctt ccaaatgctg aatacatgat tcaccaacca atgggcggta caggtggtgg
     8821 tacccaacaa actgatatgg ctatcgctgc agaacacttg ctcaaaactc gtaatacctt
     8881 ggaaaaaatc ttggctgaaa attcaggtca gtcaatggaa aaagtccatg cagatgcaga
     8941 acgtgataac tggatgagcg cccaggaaac acttgaatat ggctttattg atgaaattat
     9001 ggccaacaat tcattgaact aatgatgata gaaggcaaac tcgactgggt ttgctttttt
     9061 tggtataata gggagagatt tcttagaaag aggatttatc atgtttgaaa aagtcaatcg
     9121 ctctggcttg attatctatc tttactataa tcgtgatgcc aaaaaactgc aggattatgg
     9181 agatattacc tatcattcca agaaacatcg ttacttacaa ctctatgttc caactcaaga
     9241 agtggagcaa ttggtcggac gcttgagcaa ggaaaaattt attaaaaaag ttagggtttg
     9301 tcatatccaa gagttggaaa caccctttgt gggcaatctt tatcgatagg aaaacgttat
     9361 catcgaaaaa gttcaaggaa aacattgaca attttctgat aattcggtat attcttaaca
     9421 gactatttaa gaaataagga gacaaaaaag atgaagaaaa aatttgccct atcgtttgtg
     9481 gcgcttgcaa gtgtagcact tcttgcagcc tgtggagaag tgaagtctgg agcagtcaac
     9541 actgctggta actcagtaga ggaaaagaca attaaaatcg ggtttaactt tgaagaatca
     9601 ggttctttag ctgcatacgg aacagctgaa caaaaaggtg cccaattggc tgttgatgaa
     9661 atcaatgccg caggtggtat cgatggaaaa caaatcgaag taatcgataa agataataag
     9721 tctgaaacag ctgaggctgc ttcagttaca actaaccttg taacccaatc taaagtatca
     9781 gcagtcgtag gacctgcgac atctggtgcg actgcagctg cggtagcgaa cgctacaaaa
     9841 gcaggtgttc cattgatctc accaagtgcg actcaagatg gattgactaa aggtcaagat
     9901 tacctcttta ttggaacttt ccaagatagc ttccaaggaa aaattatctc aaactatgtt
     9961 tctgaaaaat taaatgctaa gaaagttgtt ctttacactg acaatgccag tgactatgct
    10021 aaagggattg ccaaatcttt ccgcgagtca tacaagggtg aaatcgttgc agatgaaact
    10081 ttcgtagcag gtgacacaga cttccaagca gcccttacaa aaatgaaagg gaaagacttt
    10141 gatgctatcg ttgttcctgg ttactataat gaggctggta aaattgtaaa ccaagcgcgt
    10201 ggcatgggaa ttgacaaacc aatcgttggt ggtgatggat tcaacggtga ggagtttgta
    10261 caacaagcaa ctgctgaaaa agcatcaaac atctacttta tctcaggctt ctcaactact
    10321 gtagaagttt cagctaaagc taaagccttc cttgacgctt accgtgctaa gtacaatgaa
    10381 gagccttcaa catttgcagc cttggcttat gattcagttc accttgtagc aaacgcagca
    10441 aaaggtgcta aaaattcagg tgaaatcaag gataaccttg ctaaaacaaa agattttgaa
    10501 ggtgtaactg gtcaaacaag cttcgatgca gaccacaaca cagtcaaaac tgcttacatg
    10561 atgaccatga acaatggtaa agttgaagca gcagaagttg taaaaccata atagaaaaat
    10621 gttgaaatag ggaatgagcc tttgactcac tccctgtttc gatatttaat actcttcgaa
    10681 aatctcttca aactgcgtca acgtcgcctt ggattatata tgtgactgac ttcgtcagtc
    10741 ttatctacaa cctcaaagca gtgctttgag caacctgcgg ctagtttcct agtttgctct
    10801 ttgattttca ttgagtataa gaacctatca aaaagtgagg gaaaaccctc ggaattataa
    10861 atagaaagag tgaatcttat gctccaacaa ctcgtaaatg gtttgattct aggtagtgtt
    10921 tacgcgctgt tagccctagg atataccatg gtttacggaa ttatcaagct catcaacttc
    10981 gcccatggtg atatttatat gatgggagcc tttatcggtt atttcttgat caattctttc
    11041 caaatgaatt tctttgtagc gcttattgta gctatgctag cgacagctat tcttggtgtc
    11101 gtgattgagt ttcttgctta ccgacctttg cgccactcta ctcgtattgc tgttttgatt
    11161 acggctattg gggtttcttt cctattggag tatggaatgg tctatctggt tggtgccaat
    11221 acccgtgcct tccctcaagc gattcaaaca gttcgatatg atttgggacc aattagctta
    11281 acaaatgtgc agttaatgat tttggccatt tccttgattt tgatgatttt gttacaagtc
    11341 attgtccaaa agactaagat ggggaaagcc atgcgtgcag tatcagtaga tagcgacgcg
    11401 gcacaattga tggggatcaa tgtaaaccgt acgattagct ttaccttcgc tttgggttct
    11461 gctcttgcgg gtgcggctgg tgttctgatt gctctttatt ataactctct tgagcctttg
    11521 atgggggtta ctccaggtct taaatctttc gttgccgcag tacttggtgg tatcggaatt
    11581 attcctggtg cggctcttgg tggctttgtg attggtctat tggaaacctt tgcgacagcc
    11641 tttgggatgt cagatttccg tgatgccatt gtttatggaa tcttgttgtt gatcttgatt
    11701 gtccgcccag ctggtatcct tggtaagaat gtgaaagaga aggtgtaaac gatgaaggaa
    11761 aatttaaaag ttaatattct atggttactc cttttgttag ctggctatag cttgattagt
    11821 gtactggttt cagtcggagt acttaatcta ttctatgtac agattttaca acaaattgga
    11881 attaatatta ttttggctgt tggtctcaac ttaatcgttg gtttttcagg acaattttca
    11941 cttggtcatg ctggtttcat ggcgattggt gcctatgcag cagctattat tggttctaaa
    12001 tcaccaacct acggtgcctt ctttggagct atgcttgtag gggctttgct ttcaggagca
    12061 gttgccttac ttgtcggtat tccaaccttg cgcttgaagg gggactatct tgcggtagca
    12121 actctgggtg tttctgaaat tatccgtatc tttatcatca atggtggaag tcttacaaat
    12181 ggtgcggcag gtatcttagg gattcctaac tttacaactt ggcaaatggt ttacttcttt
    12241 gtcgtgatta caaccattgc aaccttgaac ttcttgcgta gcccaattgg ccgttcaacc
    12301 ctctctgttc gtgaagatga aatcgctgct gagtcagttg gggttaatac gactaaaatt
    12361 aaaatcatcg cttttgtctt tggtgccatt actgcaagta ttgctgggtc acttcaggca
    12421 ggatttatcg ggtctgttgt accgaaagat tacaccttca tcaactcaat caacgttttg
    12481 attattgttg tatttggtgg actcggttcc attacaggtg cgattgtttc ggctattgtt
    12541 ctgggaattt tgaatatgct tctccaagat gttgctagtg tgcgtatgat tatttacgct
    12601 ttggccttgg tattggtaat gattttcaga ccaggtggac tccttggaac gtgggaactg
    12661 agcctatcac gtttctttaa aaaatctaag aaggaggaac aaaactaatg gcattacttg
    12721 aagtaaaaca gttaaccaaa cattttggtg gtctaacagc tgttggagat gtgactcttg
    12781 aattgaacga aggggaactg gttggattaa tcggtccaaa cggagctggg aaaaccaccc
    12841 ttttcaacct tttgaccggt gtttatgaac caagcgaggg aacagtaacc ctagatggtc
    12901 accttttgaa tgggaaatca ccttataaga ttgcctcttt gggacttgga cgtactttcc
    12961 aaaatatccg tctttttaaa gatttaacag ttttagacaa tgttttgatt gcttttggaa
    13021 accatcacaa acagcatgtt tttactagtt tcttacgctt accagctttt tacaagagtg
    13081 aaaaagaatt aaaggctaaa gctttggaat tgttgaaaat ctttgattta gatggtgatg
    13141 cagagactct tgctaaaaat ctttcctacg gacaacaacg tcgtttggaa attgttcgtg
    13201 cccttgctac ggaacctaaa attctcttct tagatgaacc agcagcaggt atgaacccac
    13261 aggaaacagc cgaattgact gagttaattc gtcgtatcaa agatgagttt aagattacaa
    13321 tcatgttgat tgaacacgat atgaatctgg tcatggaagt aacagaacgt atctacgtac
    13381 ttgaatatgg ccgtttaatc gctcaaggaa ctccagacga aattaagacc aataaacgcg
    13441 ttatcgaagc ttatctagga ggtgaagcct aatgtctatg ttaaaagttg aaaatctttc
    13501 tgtgcattac ggtatgatcc aagcagttcg tgatgtaagc tttgaagtta atgaaggaga
    13561 agttgtttcc cttatcggtg ccaacggtgc aggtaagaca actattcttc gcaccttgtc
    13621 aggtttggtt cgaccaagtt caggaaagat tgaattttta ggtcaagaaa tccaaaaaat
    13681 gccagctcag aaaatcgtgg caagtggtct ttcacaagtt ccagaaggac gccacgtctt
    13741 tcctggcttg actgttatgg aaaatcttga aatgggagct ttcttaaaga aaaatcgtga
    13801 agaaaatcaa gctaacttga agaaggtttt ctcacgcttt cctcgtcttg aagaacggaa
    13861 gaaccaagat gcagccactc tttcaggggg ggaacaacaa atgcttgcca tgggacgcgc
    13921 cctcatgtca acaccaaaac ttcttctttt agatgaacca tcaatgggac ttgccccaat
    13981 ctttatccaa gaaatttttg atatcattca agatattcag aagcaaggaa caacggtcct
    14041 cttgattgaa caaaatgcca ataaagcact tgcaatctct gaccgaggat atgtactgga
    14101 aacagggaaa atcgtcctat caggaacagg aaaagaactc gcttcatcag aagaagtcag
    14161 aaaagcatat ctaggtggct aaaacaatcc agtggattgt tttagtcggc agatggagat
    14221 tacgaagtaa tcatcaatat agtccggggg acctttttag tcggtagatt gagattgcaa
    14281 acaaatctgc atctacattg aaagcttaat ttctaataat tgaaaaaatc gaatgaaaaa
    14341 tttcttacct tcattcacag agctcgattt cagagctctt tttgctagct tattcatact
    14401 tttctgaatt tcgaaaaaga aatgtaagcg tttgatagat ttacaaaaag attgtataat
    14461 agggataaga atagaaaagg agaagtctca tggcagttaa agattttatg acccgcaagg
    14521 tagtttatat tagtccagat acaacagtat ctcatgcagc agatttgatg agagagcaag
    14581 gtttgcaccg tctgcctgtt atcgaaaatg atcaattagt tggtttggtg actgagggaa
    14641 ccattgcaca agcaagtcca tctaaagcaa caagtctttc tatctatgag atgaattatc
    14701 ttctgaataa gacaaaagta aaagatgtca tgattcgcga tgttgtcact gtctcaggct
    14761 atgctagtct agaagatgca acttatctga tgttgaaaaa taagattagt attctccctg
    14821 tcgtagataa ccatcaagta tacggagtta ttactgaccg tgacgttttc caagcctttc
    14881 ttgaaattgc aggttatggc gaagaaggga ttcgtgtacg ctttgttaca gaagatgaag
    14941 ttggtgttct tggaaaaatt gtttctttga ttgtagaaga aaatttgaat atctcccata
    15001 cagtcaatat tccgcgtaag gatggtaagg tgattatcga agtgcaaatc gatggatcaa
    15061 ttgatttacc agccttgaaa gaaaaatttg aagcaaatgg tattcaagtg gaagaaatcg
    15121 ctcgcacttc agcaaaagtc ttgtaagaag ggaagcccaa aggcttcttt tttcatgaaa
    15181 aggggattag agaaaaagat ggaaagaaat gataaaatat gctataatga aataatgtaa
    15241 aaaaggagta tttatggaca tttcagtaat tcgtcagaaa attgacgcaa atcgtgaaaa
    15301 attagcttct ttcagggggt ctctttgacc tcgaagggct agaggaagag attgccatct
    15361 tggaaaacaa gatgacagaa cctgattttt ggaacgataa tattgcggcc caaaaaacgt
    15421 cgcaagaatt aaatgaatta aaaaacactt acaatacctt ccataagatg gaagagttgc
    15481 aggatgaagt cgaaatttta ttggattttt tggctgaaga cgagtcagtg catgatgaac
    15541 tggtagcgca gttagccgaa cttgataaga taatgaccag ctacgagatg actctactct
    15601 tgtcagaacc ttatgaccac aacaatgcca tcttggaaat ccatccaggt tctggtggta
    15661 ctgaggcgca ggactggggt gatatgttgc ttcgtatgta tactcgttat ggtaatgcta
    15721 aaggctttaa agtggaagtg ttggattacc aagcaggtga tgaggctggt attaagtcgg
    15781 taactttatc atttgaaggg cctaatgcct atggtctcct caagtcagaa atgggtgttc
    15841 accgcttagt gcgaatctca ccatttgact ctgccaaacg tcgccatacc tctttcacat
    15901 ctgtagaagt gatgccagaa ttggatgata ctattgaagt ggaaatccgt gaagatgata
    15961 tcaagatgga taccttccgt tcaggtggtg ccggtggaca aaacgtcaat aaggtttcaa
    16021 caggtgtacg tttaacccac attccaactg gaattgttgt ccaatcaaca gtggatcgta
    16081 cccagtatgg aaatagagat cgtgccatga agatgttgca ggctaagctc tatcaaatgg
    16141 agcaagagaa gaaggctgca gaggtagatt ctctcaaagg tgagaaaaag gagatcactt
    16201 ggggaagcca aatccgttct tatgtcttca cgccttatac tatggtaaaa gatcaccgaa
    16261 ctagctttga ggttgctcag gtagataagg ttatggatgg ggacctagat ggttttatcg
    16321 atgcttatct caagtggcga attagctaag atagaaagga actcacatgt caattattga
    16381 aatgagagat gtcgttaaaa aatacgacaa cggaacgact gctctacgcg gtgtttcggt
    16441 tagcgttcaa ccgggggaat ttgcttacat cgtaggacct tcaggagcag ggaagtcaac
    16501 ttttattcgt tctctgtatc gtgaagtaaa aatcgataaa ggaagcctat cagttgctgg
    16561 ttttaatctg gttaagatca aaaagaaaga tatcccgctt ctacgtcgta gtgttggggt
    16621 tgtcttccag gattataaat tgttaccaaa gaaaactgtc tatgaaaata ttgcttacgc
    16681 tatggaagta atcggggaaa atcgccgtaa tatcaaaaga cgagtgatgg aagttttgga
    16741 cttggttgga ttgaagcata aggttcgttc tttcccaaat gaactctcag gtggggagca
    16801 acagcggatt gcgattgcgc gtgcaattgt aaataatccc aaagtattga tagctgatga
    16861 gccaacagga aatctggatc cggataattc atgggaaatt atgaatctct tggaacggat
    16921 taacctacaa ggaacaacta ttttgatggc gactcataat agccagattg taaatacctt
    16981 gcgccaccgt gtcattgcca ttgaaaatgg ccgtgtcgtt cgtgacgaat caaaaggaga
    17041 gtatggatac gatgattagt agattttttc gccatttatt tgaagcctta aaaagtttga
    17101 aacgaaatgg ttggatgaca gtagctgctg tcagttcagt catgattact ttgaccttgg
    17161 tggcaatatt tgcatctgtt attttcaata cagcgaaact agctacagat attgaaaata
    17221 atgtccgtgt agtagtttat atccgaaagg atgtggaaga taatagtcag acaattgaaa
    17281 aagaaggtca aactgttaca aataatgact accacaaggt atatgattct ttgaagaaca
    17341 tgtctacggt taaaagtgtt accttttcaa gtaaagaaga acaatatgaa aaattaaccg
    17401 agataatggg agataactgg aaaatctttg aaggagatgc caatcctctc tatgatgcct
    17461 atattgtaga ggcaaacact ccaaatgatg taaaaactat agccgaagat gctaaaaaaa
    17521 ttgaaggtgt ctctgaggtt caagatggcg gtgccaatac agaaagactc ttcaagttag
    17581 cttcatttat ccgtgtttgg ggactaggga ttgccgcttt gttaattttt atcgcagttt
    17641 tcttgatttc aaataccatt cgtattacca ttatttcccg cagtcgcgaa attcaaatca
    17701 tgcgcttggt cggagctaaa aacagttata tccgtggacc gttcttgtta gaaggagcct
    17761 ttatcggttt attgggagct atcgcaccat ctgttttggt ctttattgtt tatcaaattg
    17821 tttaccaatc tgtcaacaaa tcgttggtag ggcaaaatct atccatgatt agtccagatt
    17881 tatttagtcc gttgatgatt gccctactat ttgtgattgg ggttttcatt ggttcattgg
    17941 gatcaggaat atccatgcgc cgattcttga agatttaggt aaaatagctg cttttatgag
    18001 gagattgtaa aatctccttt tttgctacaa gagtttttga aaagagatgc gcagaagaaa
    18061 agagcttcca aagaagtccc ccagagaaga cttcttgatg gctaatttga acttgaaatt
    18121 tggcaaaaat ttctagtgcg ccaaatt
//
LOCUS       DAVKMO010000041        18052 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVKMO010000041 DAVKMO010000000
VERSION     DAVKMO010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18052
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.041"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            314..1360
                     /gene="pheS"
                     /locus_tag="VW361_001529"
     CDS             314..1360
                     /gene="pheS"
                     /locus_tag="VW361_001529"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU9744542.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKIISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1360..1869
                     /locus_tag="VW361_001530"
     CDS             1360..1869
                     /locus_tag="VW361_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744543.1"
                     /translation="MIRKVEMADVEVLAKIAKQTFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMQEEEIAAFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1946..4351
                     /locus_tag="VW361_001531"
     CDS             1946..4351
                     /locus_tag="VW361_001531"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU9744544.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVELPAAGLSK
                     IVVGEVLSCEAVPETHLHVCQINVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKKFTLTETNEAAADALSVSIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARDGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVIQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4419..5420)
                     /locus_tag="VW361_001532"
     CDS             complement(4419..5420)
                     /locus_tag="VW361_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9744545.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5568..5971
                     /locus_tag="VW361_001533"
                     /pseudo
     CDS             5568..5971
                     /locus_tag="VW361_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6097..6363
                     /locus_tag="VW361_001534"
     CDS             6097..6363
                     /locus_tag="VW361_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9744546.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            6624..8873
                     /gene="metE"
                     /locus_tag="VW361_001535"
     CDS             6624..8873
                     /gene="metE"
                     /locus_tag="VW361_001535"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU9744547.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            8937..9803
                     /gene="metF"
                     /locus_tag="VW361_001536"
     CDS             8937..9803
                     /gene="metF"
                     /locus_tag="VW361_001536"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU9744548.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQTPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10488..12701
                     /gene="pnp"
                     /locus_tag="VW361_001537"
     CDS             10488..12701
                     /gene="pnp"
                     /locus_tag="VW361_001537"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU9744549.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12717..13334
                     /gene="cysE"
                     /locus_tag="VW361_001538"
     CDS             12717..13334
                     /gene="cysE"
                     /locus_tag="VW361_001538"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU9744550.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13346..14230
                     /locus_tag="VW361_001539"
     CDS             13346..14230
                     /locus_tag="VW361_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744551.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERGTASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14312..15655
                     /locus_tag="VW361_001540"
     CDS             14312..15655
                     /locus_tag="VW361_001540"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU9744552.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15648..16034
                     /locus_tag="VW361_001541"
     CDS             15648..16034
                     /locus_tag="VW361_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU9744553.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16038..16922
                     /locus_tag="VW361_001542"
     CDS             16038..16922
                     /locus_tag="VW361_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU9744554.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            17059..17493
                     /locus_tag="VW361_001543"
                     /pseudo
     CDS             17059..17493
                     /locus_tag="VW361_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17801..17971
                     /locus_tag="VW361_001544"
                     /pseudo
     CDS             17801..17971
                     /locus_tag="VW361_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT         5438 a         3475 c         4091 g         5048 t
ORIGIN      
        1 gctataaagt tagataagaa taagctaaca agcagaagta agataggtct tgcaagaatg
       61 gtaaaaatct gataaactaa gtagtaattg aataggaatc tgaaagacta gtagcccaag
      121 ggaagtatat cagggaggag agccgtgact gcaagctctc tatatgaaag ctgggtgaat
      181 tcacttgcgc atggatttag aaatgaaggt ctgacttgtc agatgaaaac ggatggtacc
      241 gcgtgtcaac gctccgagtg gagtttttgg catgtggttt tctttttatc tacgagagac
      301 tgatggagga aatatgtcaa ctattgaaga acaattaaaa gcgcttcgcg aagaaacgct
      361 gactagcttg aagcagatta ctgctggaaa tgaaaaagag atgcaagatt tgcgtgtctc
      421 tgtccttggt aaaaagggtt cgcttactga aatcctcaaa gggatgaaag atgtttctgc
      481 tgagatgcgt ccaatcatcg ggaaacacgt caatgaagct cgtgatgtct tgacagctgc
      541 ttttgaagaa acagctaagc tcttggaaga aaagaaagtc gcggctcaac tggctagcga
      601 gagtatcgat gtgacgcttc caggtcgtcc agttgcgact ggtcaccgtc acgttttgac
      661 acaaaccagt gaagaaatcg aagatatctt catcggtatg ggttatcaag tcgtggatgg
      721 ttttgaagtg gagcaagact actataactt tgaacgtatg aaccttccaa aagaccaccc
      781 agctcgtgat atgcaggata ctttctatat cactgaagaa atcttgctcc gtacccacac
      841 gtctccagtt caggcacgtg ctatggatgc ccatgatttt tctaaaggtc ctttgaagat
      901 aatctcgcca gggcgtgtct tccgtcgcga tacggacgat gcgacccaca gtcaccaatt
      961 ccaccaaatc gaaggcttgg tagttgggaa aaatatctct atggctgatc ttcaaggaac
     1021 gcttcagttg attgtccaaa aaatgtttgg tgaagagcgt caaattcgtt tgcgtccatc
     1081 ttacttccca ttcacagagc catctgttga ggtggatgtt tcttgcttca aatgtggtgg
     1141 agaaggctgt aacgtatgta agaaaacagg ttggatcgaa attatggggg ccggtatggt
     1201 tcacccacgt gtccttgaaa tgagtggtat cgatgcgact gtatactctg gctttgcctt
     1261 tggtcttgga caagagcgtg tagctatgct ccgttatgga atcaacgata tccgtggatt
     1321 ctaccaagga gatgtccgct tctcagaaca gtttaaataa tgattagaaa agtagaaatg
     1381 gcagatgttg aggtgttggc taaaattgcc aaacaaacct ttcgtgaaac ctttgcgtat
     1441 gataatacgg aagagcagtt acaggaatac tttgaagagg cttatagtct gaaaactttg
     1501 tcaactgagt tgggaaatcc tgactctgaa acctatttca ttatgcagga ggaggagata
     1561 gctgcttttc tcaaagtcaa ctggggaagt gctcaaactg agagagaatt agaggacgct
     1621 tttgaaattc aacgcctcta tgtgctacaa aaattccaag gatttggact aggtaagcaa
     1681 ctgtttgaat ttgctcttga acttgctaca aaaaatagtt tttcttgggc ttggctaggt
     1741 gtttgggagc ataatacaaa agctcaagcg ttttataacc gatatggttt tgaaaaattt
     1801 agccaacatc attttatggt tggtcaaaaa gtagatacgg attggttact gagaaagaaa
     1861 ttaaggtaag aagaggattc ttctattgaa atgataggaa aggaaaagaa ctagagtgac
     1921 aactgtcatt ctggagaact aaattatgct tgtatcttat aaatggttaa aagaattggt
     1981 ggacattgat gtgccatcac aagagttggc tgaaaaaatg tcaactacag ggatcgaggt
     2041 agagggtgtc gaattaccag ctgctggtct ctcaaaaatt gtcgtcggtg aggtcttgtc
     2101 ttgcgaagct gtgccagaga ctcacctcca tgtttgtcag attaacgttg gcgaagaaga
     2161 agagcgtcag atcgtttgtg gtgccccaaa tgtgcgtgct gggatcaagg tcatggtggc
     2221 tcttccagga gctcgtatcg ctgataacta caaaatcaaa aaaggaaaaa tccgtggttt
     2281 ggagtcactt ggaatgatct gttcacttgg tgaattggga atttctgact cagttgtgcc
     2341 taaggaattc gcagatggca tccaaatctt gcctgaagat gccgtgccag gtgaggaagt
     2401 cttttcttac ctagacttgg atgatgaaat catcgaactt tccatcacac caaaccgtgc
     2461 agatgccctt tctatgtgtg gagtggctca cgaagtggca gccatctatg acaaggcagt
     2521 caactttaaa aaatttactc taacagaaac taatgaagct gcggcagatg ccctttctgt
     2581 cagcattgag acagacaagg cgccttacta tgcagctcgt atcttggaca atgtgactat
     2641 cgcaccaagt ccacaatggt tgcaaaacct tctcatgaac gaaggcatcc gtcccatcaa
     2701 taacgttgta gacgtgacaa actacatcct gctctacttt ggtcaaccta tgcatgcttt
     2761 tgacttggac acatttgaag ggactgacat ccgtgtgcgt gaagcgcgtg atggtgaaaa
     2821 attagtgacc ctggacggtg aagaacgaga cttggctgag acagacctcg tgattacagt
     2881 tgctgacaaa ccagtagccc ttgccggtgt tatgggtggt caggctacag aaatttctga
     2941 aaaatctagt cgtgttatcc ttgaagctgc tgtttttaat ggcaaatcta tccgtaagac
     3001 aagtggtcgc ctgaaccttc gttctgagtc atcttctcgc tttgaaaaag gaattaatgt
     3061 ggcaacagtt aatgaagccc ttgatgcggc agctagcatg attgcagagc ttgcaggcgc
     3121 gacggtgcgt aagggtatcg tttcagcggg tgagcttgat acctctgatg tggaagtttc
     3181 ttcaaccctt gctgatgtta accgtgtcct cggaactgag ctgtcttatg ctgatgtaga
     3241 agacgtcttc cgtcgtcttg gctttggtct ttctggaaat gcagacagct ttacagtcag
     3301 cgtaccacgt cgtcgttggg atatcacaat cgaagctgat ctctttgaag aaatcgctcg
     3361 tatctatgga tatgaccgct tgccaaccag ccttccaaaa gacgatggta cagctggtga
     3421 attgactgtg atacaaaaac tccgccgtca agttcgtacc attgctgaag gagcaggttt
     3481 gacagaaatc atcacctatg ctctgacaac tcctgaaaaa gcagttgagt tcacagctca
     3541 accaagtaac cttactgaac tcatgtggcc aatgactgtg gatcgttcag tcctccgtca
     3601 aaatatgatt tcagggatcc ttgataccgt tgcctacaac gtggctcgta agaataaaaa
     3661 cttggccctt tatgagattg gaaaagtctt tgaacaaaca ggtaatccaa aagaagaact
     3721 tccaaatgag atcaacagct ttgcctttgc cttgacaggc ttggttgctg aaaaagattt
     3781 ccaaacagca gcagttccag ttgatttctt ctatgctaag ggaatccttg aagccctatt
     3841 tactcgtttg ggactccaag taacctatac agcaacatct gaaatcgcta gccttcatcc
     3901 aggtcgtaca gccgtgattt cactcggtga ccaagttctt ggtttccttg gccaagtgca
     3961 tccagtcact gccaaggctt acgatattcc agaaacgtat gtagctgagc ttaacctttc
     4021 agccatcgaa ggggcgctcc aacctgctgt tccatttgtg gaaatcacca aattcccagc
     4081 agtcagccgt gacgttgccc ttctcctcaa ggcagaagtg actcaccaag aagttgtaga
     4141 tgctatccaa gctgccggcg tgaaacgttt gacagatatc aaactctttg acgtcttctc
     4201 aggtgaaaaa ctgggacttg gtatgaagtc aatggcttat agcttgacct tccaaaatcc
     4261 agaagacagc ttaacggacg aagaagtcgc acgctacatg gaaaaaatcc aagcgtctct
     4321 cgaagaaaaa gtcaatgcag aagtgcgtta aacgatagta ggatacaaat tccccctcta
     4381 gtttatgaac actagagggg tgattttata taaaataatt aaaatgtgat ttctgtaaaa
     4441 atacatctat gatcagagtt ttgaaaactt acaatgtcta aatctttaac atagtagtgg
     4501 tttttaggca ataaaatatg atctattgtt gcattaaaaa gttttggact ttggctattc
     4561 caagttcctc tttcaaaagg tggcagtaca tttaatgcgt ccctatgaga gcttattttt
     4621 gcaagtgctc catgacgcat agttgcatta aaatcacctg caataatagc ctttggatat
     4681 tttgaagcca attgattatg aatgatgttt aagtcttgct tccagatttc cattaaacct
     4741 ggcagaggag gagcagtatg caaggcaatg atatctggta tattttgttt tctcgaatgt
     4801 aatacaattg tcccgaaccg tgttgtatga aaagttttag cttctgtata gaaaccataa
     4861 cttttcttga caatcacagt cacaggagct attccactat tggtaggtgg agaagtgaaa
     4921 atatcatagt tggccataga aagtccaact tgatgaaaca atagtttgat tctctggttt
     4981 tcttgctcac ctctgatatt ggtagctagt tcagggaata tagccatatc ggcgtcaaaa
     5041 tggctaaaaa ttcgctcaat atgttgtgct tctatttgat tagcgacgtt ccaagttact
     5101 aattttaagg ttttagtctt atttgatgca gaagaaaggg ttttatctgt tccgaataat
     5161 agtaatatga gcgatagtaa gagcaaaatg ccagagtaaa accgtatttg tttatttttc
     5221 ttgtaaaaag atagggaaaa aaatacgaaa cttaaaatag aagccatagt tgcagtagct
     5281 aaggggaagg cataaatctg tgccaagata ggttgggtag atagccaaat attaagatta
     5341 gaagatggaa aaaaagaata agctatgata gggataacaa agagaatgac cgaaagggca
     5401 gagagaaatg ttttaatcat tgtgtgagta cctcaatttg caatggttgc tcggagctaa
     5461 tgtgacttta cttgattgat attctttttc ttgtcttcct tatagattaa gtacaaccca
     5521 agtaaaaaaa gtccaattta agattgaaat gattaaaagg cacagaaatg caagacaatt
     5581 atactacaaa aggcaaacat ttgacaatcg atagccgtcg cttaatcgaa cgatggaaaa
     5641 aagaaggaaa atcaaataga gaaattgcct ctctacttgg aaaagctcct caaactatcc
     5701 acactgaaat aaagcgtggg acagtccgac aatgtcttgg aaaagggcgc ttcaaagaga
     5761 tttattctgc cgactacgct caacagtctt aagaaactaa aggaaaagat tctccactat
     5821 acataaccaa aaattttcgc ctgaaatgat ggttatggct aaaggggtta acgtgggaat
     5881 ttcaaccatt tactattgga ttcatcgtgg aaaattgggg ttaagcaagc aggatctgct
     5941 ttatcctaga aaaggaaaat cgcttaagaa ataggctagc accaacttta aacccactgg
     6001 tcaatctatc gaatcataat tcgctcattt ttttaaaaat acatagacgt aaaaaaaaga
     6061 gggttaagtg atgaagaata gtgctattgg gagtaattgg aaggatgtcc atctgagctc
     6121 tttagcaagg aggaaatcct tgaaagtgat atgcgagtgg ctatcatgag cgagttgatt
     6181 gaggctaggt atgaacaagg aatcagtcag aaaaagctgg aagaagtcag tggaataagc
     6241 cagcctgtca tagctaggat ggagacagga aagactagtc ctcagttgga tacagtctta
     6301 aaagtcctag ccagtttagg aaagacacta gcaatcgtcc cacttgaaca gggaaaaagt
     6361 tgactagaat cagttatagt cttttctaat aacaggtcat agtcacttat aagaattact
     6421 aataacatgt tttagtattc taattggaat atagctgtaa agtaagaatt acaaaggatt
     6481 tgagacgttt gcttcaagtc tttttctttt gtccgaaaca gatatatagt ttcaaactat
     6541 atcaaaccct aattttttac aattatacag acgctttctt ttctgttaag atagtttcaa
     6601 caacaaattt tggaggacac atcatgtcaa ctacaatcat cggtttccct cgtttgggcg
     6661 aattccgtga attaaaattt acaactgaaa aatactttag aaaagaaatc tcagaagaag
     6721 aacttttagc agcagcaaaa gacttgcgtg ctaaacactg gaacattgtc aaagaaaaag
     6781 gcatcactga aatcccatca aatgactttt ctcactatga taacttccta gatgcggctt
     6841 tccttttcaa cgtagtgcct gcctcagttc aaaacttgga cttgtctgac cttgagcgct
     6901 acttcgcttt gggacgtggt taccagggag aaaaagggga cgttcgcgcc cttccaatga
     6961 agaaatggtt caacactaac taccactaca tcgttcctaa atttgaaaaa gacactcaag
     7021 taaaattggc tggtcacaag attttcgatg agttccaaga agccaaagaa cttggattga
     7081 acactcgtcc tgttcttgta ggtcccttca ctttccttca attgtcagac tttgaagaag
     7141 gcgtgaaagc agacgacttc gtagatagct tagtggctgc ttaccaagaa gtttttgcta
     7201 aattggctga acttggtgcg actcgcatcc aattggatga agcggctctt gtaaaagact
     7261 tgacagctga agaaaaagct ctcttcttga acctttacaa caaactcttg gctgacaaaa
     7321 aaggtcttga agtcttgctt caaacttatt tcggtgatgt tcgtgacgta tacgctgacc
     7381 ttgtaaactt accagtagat gctatcggtc ttgactttgt tgaaggtaag aaaactcttg
     7441 aactcgttaa aggtggcttc ccagctgaca agactctcta tgtaggtatt gtcaatggta
     7501 aaaacatctg gcgcaacaac tacgaaaaga gcttggctgt tcttgagcaa atcccagctg
     7561 aaaacatcgt tttgacaagc tcttgctcac ttcttcatgt gccatttaca actgctaatg
     7621 aagaatttga accagcactc ttgaaccact ttgcctttgc agttgaaaaa ttggatgaaa
     7681 tccgtgactt ggatgctatc cgcaatggtc aaggttcaga agctcttgca gccaacaaag
     7741 aactctttgc gactgagcgt gttggtgaaa atgctgaact tcgtgcgcgt atcgctggct
     7801 tgacagacgc agactacact cgtttgccag cctttgcaga acgtgaagct atccaagaag
     7861 aagctttcaa acttccagct cttccaacaa caacgattgg ttcattccct caaacaaaag
     7921 aagttcgtgc caaacgtttg gcttaccgta aaggtgaatt gtctcaaaaa gagtacgatg
     7981 ctttccttgc tgaaacgatt gacgaatgga tcaagtggca agaagatatt gactttgatg
     8041 tccttgttca cggtgaattt gagcgtaatg acatggttga gtacttcggt caaaacttgt
     8101 caggatacct cttctctaaa aatggatggg tacaatcata cggtatgcgt ggggtaaaac
     8161 caccaatcat ctggggtgat gtcactcgtc ttaaccctat cactgttaaa tggtctagct
     8221 atgcacaaag tcgtacaaac aaacctgtta aaggtatgtt gactggacct gttaccatcc
     8281 ttaactggtc attcccacgt gaagacatct ctatcaagga ttcaactctc caaatcgccc
     8341 ttgctatcaa ggatgaagta cttgaccttg aagctgctgg tgtgaaaatc atccaaatcg
     8401 acgaggctgc tcttcgtgaa aaattgccac tccgccgtag cgactggtac gaagactacc
     8461 ttgactgggc tattcctgcc ttccgcttgg tacactcaac agtagcgcca gacacacaaa
     8521 tccacactca catgtgttac tcagaattta cagatatcat cccagctatc gataacatgg
     8581 atgcagacgt tatttccttt gaagctagcc gttcaaacct tgaaatcttg gacgaactca
     8641 aagcgaaaaa cttccaaaca gaagtgggac ctggggttta cgatatccac tcacctcgtg
     8701 taccaaatga aggcgaaatc gacaacacaa tcgaagccat ccttgctaaa gtgccaagca
     8761 agaaagtttg gatcaaccct gactgtggtt tgaaaacacg tggtatccca gaaacaaaag
     8821 aaagcttgat ccgccttgtt gaagcagcta aagctgcgcg tgagaaattg taagattgga
     8881 tttctctcca tacagtggtt gttcaaaaag aaatcaacta gaaaaggtta ttacatatgt
     8941 cacgccaaac accgtcactc tcatttgaag tgttccctcc aaacccagcc gtgggtaatg
     9001 ataacattat ttcagccttg caggatatgc aggagttggc tccccatttt atcagtgtaa
     9061 ctgccagcaa taataaattt aatatcaagg aaacgacggt tcgtttggct gactttatcc
     9121 aaaatgattt ggcgattccg accattgccc acttgccagc tatttatcta actaaggaca
     9181 aggttgctga aactattgct gacttggaca aagttggggt gcagaaaatc ttggctcttc
     9241 gtggggatat tattccagac gtggaaccac aaaaggattt ccgctatgca accgacttga
     9301 ttgagtttat caaggaacaa acccctcact ttgatattat tggagcttgc tatccagaag
     9361 ggcatccaga ttcgccaaat cagatttcag atattcaaaa tcttaagaag aaagtggatg
     9421 caggctgttc gagcctcgta actcagctct tctttgacaa tgagcgcttc tatgattttc
     9481 aggataagtg tattttggct gggattgatg ttcccattca tgcaggaatt atgccaattc
     9541 tgaatcgaaa tcaggctctc cgactcttga agacttgtga gaatatccat cttccacgca
     9601 aatttaaagc catcttagac aagtatgagc atgaccctga gtcgctcaga gcagcaggac
     9661 ttgcctatgc agtggaccaa atcgtggact tggtaactca ggatgttgcc ggtgtgcatc
     9721 tctatacgat gaataatgct gatacagcaa aatacatcca tcaagcaacc catgccttgt
     9781 ttaatcacca gtctctagga taataaaagc aaaccattct tctcaggtga ggggaatggt
     9841 tcctttttaa tggcaaagac ctcacttttt aagaaaaata tgataaaata gattctgtac
     9901 gtacttgata caaagatgaa ggtattaaat aatacaatgc atttaaactg taagatttaa
     9961 cgacacgagt gagtcaaatc gatgttattt gacgaaagag ttagtaaagc atttagctaa
    10021 tcgcccgata gcaattagcg tgaaaggttt agatacttta atattaaacc tttctaatga
    10081 tgtatcttga aaactgaact tgcctacaac tctgtggaaa aagataaatc tccctaggag
    10141 cagtcgctcc gtcgttcgat ttcctatctt cctttgagtt gcttgacggc ttggtatctt
    10201 gatgacttga attttggtct catttcttag gaaaaaagat aagcttccta gcactcgtcg
    10261 agtgcgacgt caccttccta tttttctaca gaaatgttcg gcaagccgaa ccgtccaaaa
    10321 tatcttgtgt aattgaacac ggccgaaaag ctgtgtaaaa aagataaact gtcttgtctt
    10381 catcgaagac ttcgtcagtt tcctattttt actttgcttt tgacgtcctt ggtatcttga
    10441 tctttgtagg caaggcgtat aatttcatca atccaaaggg gattaaaatg gcaaaacaag
    10501 tgtttcaaac gacttttgcg ggtcgtgagt taattgtaga gactggtcag gttgctaagc
    10561 aagcaaatgg atctgttgtc gtacgttacg gtgagtcaac tgtcttgact gctgccgtta
    10621 tgtctaagaa aatggcaact ggggatttct tcccactcca agtcaactac gaagaaaaaa
    10681 tgtatgcggc tgggaagttt cctggtggct ttatgaaacg tgaaggacgt ccttcaacag
    10741 atgcgacctt gacagcgcgt ttgattgacc gtccgattcg tcctatgttt gcggaaggtt
    10801 tccgtaatga agtccaagtc atcaatacag tgctttctta tgatgaaaat gcatctgcac
    10861 caatggctgc tatgtttggt tcatctttgg cactgtctat ttcagatatt ccatttgacg
    10921 gaccaattgc tggggtacaa gtgggatatg tagatggcca aatcatcatc aacccaagtc
    10981 aagaacaagc agagcaatct cttcttgaat tgacagtagc tggaaccaag cacgctatca
    11041 acatggtaga gtctggtgcc aaagaattgt cagaagaaat catgttggaa gcgcttctta
    11101 aagggcacga agctgtcaaa gaattgattg ccttccaaga agaaatcgtt gctgctgtcg
    11161 gtaaagaaaa agcagaagtg gaattgcttc acgtggatgc tgaattgcaa gctgaaatca
    11221 ttgcagccta caacagtgac ctccaaaagg cagttcaagt agaagagaaa ttggcccgtg
    11281 aagctgcaac tcaagcagtg aaagaccaag tgactgccgt ttacgaagaa aaatatgcgg
    11341 accacgaaga atttgaccgt attatgcgtg atgtggctga aatcttggaa caaatggaac
    11401 acgcagaagt gcgacgttta attacagaag acaaggtgcg tcctgatggt cgtaaggtcg
    11461 atgaaatccg tcctttggat gcggttgttg acttccttcc tcgtgtacat ggttcaggtc
    11521 tctttactcg tgggcaaact caagctcttt cagtcttgac cttggctccg atgggagaaa
    11581 ctcaaatcat tgatggtttg gatccagagt acaagaaacg ctttatgcac cactataact
    11641 tccctcaata ttctgtaggg gaaacaggtc gttacggtgc gccaggtcgt cgtgaaatcg
    11701 gtcacggtgc ccttggtgag cgtgctcttg ctcaagtctt gccaagcttg gaagaattcc
    11761 catacgctat ccgtctagta gcagaagttt tggaatcaaa cggttcttca tctcaagctt
    11821 ctatctgtgc gggaactctt gcccttatgg ctggtggtgt gccaatcaag gcgccagtag
    11881 ctggtattgc tatgggactt atctcagatg gaaataacta cacagtattg acagatatcc
    11941 aaggtttgga agatcacttt ggagatatgg acttcaaggt tgcaggtact cgtgatggga
    12001 ttacagccct tcaaatggat atcaagattc aagggattac tgcagaaatc ttgacggagg
    12061 ctcttgctca agccaagaaa gcgcgttttg aaatccttga tgtcattgaa gcaaccattc
    12121 cagaagttcg tccagaattg gctccaactg ctccgaaaat tgatacgatc aagattgatg
    12181 tggacaagat taagattgtc atcggtaagg gtggagaaac catcgacaag attatcgctg
    12241 aaacaggtgt taagattgat atagacgaag aaggaaatgt gtctatctac tctagtgacc
    12301 aagatgctat taaccgtgcc aaagaaatta ttgctggttt ggttcgtgaa gccaaagtgg
    12361 atgaagttta ccgtgctaaa gtcgttcgta tcgagaaatt tggtgccttt gttaacctct
    12421 ttgataagac agatgccctt gttcatatct ctgagatggc ttggactcgt accaatcgtg
    12481 tagaggattt ggtagaaatc ggggatgaag ttgatgttaa ggttatcaag attgatgaaa
    12541 aaggccgtat cgatgcctct atgaaggctc ttctacctcg tccgccaaaa cctgagcatg
    12601 atgaaaaagg tgaaaagtct gagcgccctc accgcccacg tcatcacaag gatcacaaac
    12661 ctaagaaaga atttacagaa acaccaaaag attcagagta agaaaaggag aaatgtatgg
    12721 ggtggtggcg cgaaaccatt gatatcgtaa aagaaaatga tccagcggcc cgcaccactt
    12781 tggaggtttt gctgacttat ccaggtgtca aggccttggc ggcccaccgt ctctcgcatt
    12841 ttctctggaa gtacgacttc aaactcttag ctcgtatgca cagtcagttt tggcgctttt
    12901 ggactcagat tgagattcat ccaggagccc agattgattc aggtgtcttt attgaccatg
    12961 gttctggtct ggtgattgga gagacagcga ttgttgaaaa aggcgttctt ctctatcacg
    13021 gagtgactct cgggggaaca gggaaagact gtggcaaacg ccatccgact gtacgaaagg
    13081 gagccctcat atcagcccat gcccaagtta tcgggcctgt ggaaattggt gaaaatgcca
    13141 aggtcggtgc tgcagcagtt gtcgtagcag atgtacctag tgatgtgacg gttgtcggta
    13201 ttccggccaa gattgtccgt cttcatggta agaaagatga gcctgttatt cacgaagtcg
    13261 aagaaaaacg ggagtattat gtcaataaac tcgagcaggc taaagatgcc agtcacagat
    13321 cgtctggttt gtagaggata cctatatgat tcaagcaaga aacaagttaa gccaagaaga
    13381 gctatctgag gcgaaaaaag taattaactg ttgccaaaac tatgacggta cctatcgcga
    13441 tccctatctc tctaacatgc ttaattttga tccaaacatg cccgcctttt tcctttatta
    13501 tgaaaaaggc gaacttgttg gtttattaac tgtctatgca gatgaccaag atgtagaagt
    13561 gacgatactg gttcatccag gtcatcgccg tcaggggatt gcgcgtgcat tgtttactag
    13621 ttttgagaga ggaacagctt ctttccccat tcggtcagtc acttttcaga cagaacgtat
    13681 ttttttagag aatcatcctg actttgccag taactgggga ctaatagagg atgaagagac
    13741 agaaacttgg ttaggtaagg atagaagacc ttatccgtta gcaaatgttt cccatcttga
    13801 agttttgtta gcagatagtt cgtatcagga tcaaattagt caattaaaat ttcaggcatt
    13861 ttcagaggaa catgaatcga gagaagttgt ggatagatat gtcgctgaag ctctgaagga
    13921 tccagaaagt cgcttatata ttttattaaa agacggtcag gttattggga cttgtacggt
    13981 tgatttatcg actaatacga attacttcta cggtttagca atattggaac ctgaacgtgg
    14041 aaaaggctat ggaagctact tagcaaaatc cctcgtcaac caactaattg agcaaaatga
    14101 caaggaattt cagattgcag tggaagatag caatgtaggt gccaaacgtt tgtatgaaaa
    14161 aattggcttt gtcaaacaga ctcaggtggt ttatctgaat gagaaaggag caagggattc
    14221 cgaagtgtag agatattcgg actgaaattt acttgaactt ttagtgatga aactaattgt
    14281 tcttggattt cagctttcct gattatgatt tatgattaaa atctatgaca ccatgtctcg
    14341 tgatttgcga gaatttgtcc cgattgagga cggcaagatc aagatgtatg tttgtgggcc
    14401 aacggtgtac aactatatcc acgtgggaaa cgcccgttcg acggtagctt ttgatacgat
    14461 tcgtcgctat tttgagtacc gtgggtataa ggttgcctat atttccaatt ttacagatgt
    14521 ggatgataag attatcaacc gtgccaggga agaaggcatc acgcctcagg aggttgcgga
    14581 taagtacatc gctgcctttc gtgaggatgt gacggccttg ggcgtgaaac ctgcgactcg
    14641 ccatccgcgt gtagtggagt ttatggcaga catcatccgt tttgtggaag acttgatcga
    14701 gaaaggcttt gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa aatcccacaa
    14761 ctatgctaaa ttggctaata aaaccttgga agatttggag ctaggtgctt caggtcgtac
    14821 cgatgaagaa acggctcgta aggaaaatcc tgtagacttt gctctatgga aatcttccaa
    14881 accaggtgag atttcttggg atagtccttg gggacctgga cgtccgggtt ggcatattga
    14941 gtgttcagtc atgtcgacag agattttagg tgataccatt gatatccacg gtggtggagc
    15001 tgacctagag tttccacacc acaccaatga aattgcccaa tctgaagcta aaacaggcaa
    15061 ggcttttgct aactactgga tgcacaatgg ctttgtcaat atcgacaatg tcaaaatgtc
    15121 taagtccttg ggtaacttca ttacggtaca cgatgccctt aaaactcttg atgggcaagt
    15181 acttcgtttc ttctttgcga cccagcacta ccgtaagcct atcaacttca cggaaaaggc
    15241 agttcgcgat gccgagacca atctcaagta tctgaagaat acttacgaac aaccatttac
    15301 aggaaacgtg gatgcccaag agttacaaaa ctttaaagat aagtttgtag cagctatgga
    15361 tgaagatttt aatgctgcca acggtatcac agttgtcttt gaaatggcca aatggatcaa
    15421 ctcagggaac tatgatgcaa gtgtcaagca agctcttgca gatatgttag aaatttttgg
    15481 aattgtcttt gttgaggaag ttttggatgc agagattgaa gacttgattc aaaaacgcca
    15541 agaggcgcgt gccaatcgag actttgagac agcagaccaa atccgtgacc aattggttac
    15601 tcaaggaatt aagctccttg ataccaagga tggagtgagg tggacacgtg attgatgtca
    15661 atctcattaa cgggattgcg ctagcctttg agggggatgc ggtgtattct atgtatattc
    15721 gccgtcacct catcctcaaa ggtatgacca aacccaataa actccatcaa gaagcaacca
    15781 agtatgtgtc agccaaggct caggctcgcc tgattgctct catgttggag gagcaggtcc
    15841 taacggaaaa agaagaagaa atctacaaac gtggccgcaa taccaatagc cacacaaagg
    15901 ctaaaaatgc agatgtcgtg acttatcgta tgtccacggg atttgaagcg gttatgggct
    15961 atctccatat gactgagaat ctggaacgtc ttgagagttt ggtttcatgg tgcatccaaa
    16021 aagtggaggg ctagaacatg agggaaaaag aactacaaga ctggtttcct gaggctcgga
    16081 tttcagacca accagtagag aaagagggct atctcacgct ccctttagct tctcagcagt
    16141 ggattttgct ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt gcccttttga
    16201 cccagcagga gcaggctcgt tcgctaaacc cttggtattc ctatctggtt gaaggcaagg
    16261 gacaggcacc gcaagttttt aaaaagattc agttggttta ttgccatctt tcttattttc
    16321 agcaggaaaa tctggcttct tggctagata tgatgcggac tctttttccg aattgtcaga
    16381 cagtgctaca ggtcggatct caggattatg ttttcgtgct tcaacaagac aaatacactt
    16441 ctgtaagaga tattttaagt gatacgattg aagcggttga gtatgacttt ggacttcgtc
    16501 tttctatcat gttgggtcag gtttggtctc agacgggaca tcaagcccta tcagacttaa
    16561 tcaaagctga gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa ggtgttcata
    16621 ctttttctca gctctatctt tggagtatgg gagaaagact cgtggacttg aagccaatca
    16681 aggaatgtct acaccagatg attttggatc aagatcagat tcaggaaatc attctctctc
    16741 tttgggaaaa tagtgctgtt ctcactaaaa cagcccagca actctatctg caccgcaatt
    16801 ctctccaata caagattgat aaatgggaag agttgacagg gcttcagttg aaagagttga
    16861 ccgacctgac cttgtgttat caattgattt taggttcttt gtcaactata gttggtttgt
    16921 aaagaagtta atatttggag aagaggatgg ccatcttctc catttttatg tgcagagtta
    16981 tagtggcttg atgctgggaa agtacactgt gactgctaaa acattcctag aagttgcttt
    17041 gatttcccta atctatttat gtgaatttta tgttatttta ctataacagt tgttgctaag
    17101 ctaaataata gtggggaagt ttatttagac gtaagcattg aagataatca gggaggtagt
    17161 gggtataatt tcagttctgt ttcaagtagc tcacaaacag ctaaatatga aggaactggt
    17221 tataataaca attcatcatt atatataacg attgataaaa cgtctgatgc aacagctctt
    17281 ttgaaattaa agttgaataa tgttgataat caacctgcta ctgaagttcc tagttcagga
    17341 attactgtaa aattaaatgc taaagataat gctggaaact ggacaagtgc ttcgaataaa
    17401 aaagaagtaa cagtaaaaat tgtttctgct aaaccgacat atccagacaa aattttagtg
    17461 aaaaatcctg ataatataaa agatacagaa aaaaatgcca ttattgaaaa attgaaagag
    17521 gcaaataaaa atcatccagc aggagctcca acctttgcta aaggtgaagg agagcatgca
    17581 aatgatattg tagcaactta ttcagatggt acaacttatt atgtaccgtt aaatgatgtg
    17641 acaaaatatg cgaggtagtg gctgtaccac tcacttattc acctccccgt gatttgtagt
    17701 agtgataggc tttctcacta ttattataaa acaaaataaa gatcacaaca ctttttcatt
    17761 ctgtgttgtg ccttgagtga aacgaaagga atgaattata aatatgaaaa gtatagtcac
    17821 taacatagat gagcgcttgc gtactcgcct acgagtgatt atctggaagc aatggaagaa
    17881 gaaatcgaga cgattatggg gattgcttaa gttaggggtt cctaaatgga tagcagataa
    17941 ggtatctggc tggggcgacc actatcaatt atattaaaat gaaataagaa taggacgaat
    18001 cgatcaggga agtcaaatcg atttctaaca atattttaga agtagaggta ta
//
LOCUS       DAVKMO010000042        16867 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVKMO010000042 DAVKMO010000000
VERSION     DAVKMO010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16867
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.042"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(197..655)
                     /locus_tag="VW361_001545"
     CDS             complement(197..655)
                     /locus_tag="VW361_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU9744555.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(652..1092)
                     /locus_tag="VW361_001546"
     CDS             complement(652..1092)
                     /locus_tag="VW361_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9744556.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1448..3397
                     /gene="mutL"
                     /locus_tag="VW361_001547"
     CDS             1448..3397
                     /gene="mutL"
                     /locus_tag="VW361_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU9744557.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3722..4189)
                     /locus_tag="VW361_001548"
     CDS             complement(3722..4189)
                     /locus_tag="VW361_001548"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU9744558.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(4190..5395)
                     /locus_tag="VW361_001549"
     CDS             complement(4190..5395)
                     /locus_tag="VW361_001549"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU9744559.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5415..6050)
                     /gene="ribE"
                     /locus_tag="VW361_001550"
     CDS             complement(5415..6050)
                     /gene="ribE"
                     /locus_tag="VW361_001550"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU9744560.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(6035..7135)
                     /gene="ribD"
                     /locus_tag="VW361_001551"
     CDS             complement(6035..7135)
                     /gene="ribD"
                     /locus_tag="VW361_001551"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU9744561.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7269..7383)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7540..8133
                     /gene="ruvA"
                     /locus_tag="VW361_001552"
     CDS             7540..8133
                     /gene="ruvA"
                     /locus_tag="VW361_001552"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU9744562.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            8143..8706
                     /locus_tag="VW361_001553"
     CDS             8143..8706
                     /locus_tag="VW361_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU9744563.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8703..9380
                     /locus_tag="VW361_001554"
     CDS             8703..9380
                     /locus_tag="VW361_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9744564.1"
                     /translation="MMSNKNKGILIFVILYTVLFVFDGVKLLASLMPFAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9535..10566)
                     /locus_tag="VW361_001555"
     CDS             complement(9535..10566)
                     /locus_tag="VW361_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU9744565.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKHLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(10821..11504)
                     /locus_tag="VW361_001556"
     CDS             complement(10821..11504)
                     /locus_tag="VW361_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU9744566.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11516..12460)
                     /locus_tag="VW361_001557"
     CDS             complement(11516..12460)
                     /locus_tag="VW361_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU9744567.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12592..15423
                     /gene="uvrA"
                     /locus_tag="VW361_001558"
     CDS             12592..15423
                     /gene="uvrA"
                     /locus_tag="VW361_001558"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU9744568.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHG"
     gene            15416..16477
                     /locus_tag="VW361_001559"
     CDS             15416..16477
                     /locus_tag="VW361_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9744569.1"
                     /translation="MDKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         4764 a         3341 c         3622 g         5140 t
ORIGIN      
        1 aagatctgaa ataactgtta tgatatagcg gattgaaact agaatagtac acctctgctt
       61 ctaaaacatt gttagaaatc gatttgactg tcctgatcga tttatcctgt tcttatttca
      121 tttcactata gtaaggtgca gcaggataaa gaaaaaccga gaagtttctt tctcggattt
      181 gcttattatg aggttcctat tttctatgct ccaagagttg attgatgtga tctacttttt
      241 tagcctctct tttatagaga atagcccaga tgatgagata gacaatcgca aactcgataa
      301 tgagctggag gtagaaaatc cagtggaaag ggaaccaacc agcaagagtt gctagtggga
      361 caaagccagc cagcataagg aagaaatgag tcagagtggc acgaagcatg ctccagtcac
      421 ggctgaataa gcggttgcca aagttgaaga gcataccgat ggctgcccag ataagtgtgc
      481 agtagagcaa gaccagggca ccgtgaacct gatgctgatc catcacttgg ccgatgagag
      541 agtagggatt tagtggtgcg taggtatttg gtgcataaat gagtgaaaag aggatggaga
      601 ggatgaggcc gataagaaca ccggcagctg catcgtgaaa tacttgtttt ttcatagttc
      661 taatttctcc ttgatggttt ttagataacg gcgtgaagag taggtgaagc tttcgttttt
      721 caagaaaatt tctaccagac cgtttggcgt gagcttgagg tgagagatgg aatcgatatt
      781 gatgatttct gattgggaaa tttggataaa attgcttggc aagagtttaa gaacctgata
      841 gagtcgcaaa tcaatgctgt aggtctgact cgcggtttct gctagaacct tccgattctc
      901 gatatagaag cgctgaatct tgccaatctc aactagatag acctgatcat cgatttttcc
      961 tttgattttt tctctttggt ccagattttc tgcgaactcg atgactttct ggactttttc
     1021 ggtttcttga ggtgcttgga caatcagctt ttcctcctcg taagtctcac taatctgtag
     1081 ttctactttc atagttttct ctccttgttt ttcatacaaa attaatctca cttcttgtac
     1141 acctttatta atactcttca aaaatctctt caaaccacgt cagcgtcgtc ttgccgtagg
     1201 atagttgttg actttgtcag ttttatctac aacctcaaaa cagtgttttg agctgtctgc
     1261 gcctagcttt ctagtttgct ctttgatttt tattgagtat accactattt tactccctct
     1321 ggcaagggac tttgtctatg tggagggatt gggctcctat gtggtggagc ttttctgttc
     1381 tttctgaaat atggtataat agcactaatt aatttctagg aaaatagata cagaaagggg
     1441 ctgaaagatg tctcatatta ttgaattgcc agagatgctg gcaaaccaaa tcgcagctgg
     1501 ggaggtcatt gaacgtcctg ccagtgtggt taaagagttg gtagaaaatg ccattgacgc
     1561 gggctctagt cagattatca ttgagattga ggaagctggt ctcaagaagg ttcaaatcac
     1621 ggataacggt catggaattg cccacgatga ggtggagttg gccctgcgtc gccatgcgac
     1681 cagtaagata aaaaatcaag cagatctctt tcggattcgg acgcttggtt ttcgtggtga
     1741 agccttgcct tctattgcgt ctgttagtgt cttgactctg ttaacggcgg tggatggtgc
     1801 tagtcatgga accaagttag tcgcgcgtgg gggtgaagtt gaggaagtca tcccagcgac
     1861 tagtcctgtg ggaaccaagg tttgtgtgga ggatctcttt ttcaacacgc ctgcccgtct
     1921 caagtatatg aagagccagc aagcggagtt gtctcatatc attgatattg tcaaccgtct
     1981 gggcttggcc catcctgaga tttcttttag cttgattagt gatggcaagg aaatgacgcg
     2041 gacagcaggg actggtcaat tgcgccaagc aatcgcaggg atttacggtt tggtcagtgc
     2101 caagaagatg attgaaattg agaactctga cctagatttc gaaatttcag gttttgtgtc
     2161 tttacctgag ttgactcggg ctaaccgcaa ttatatcagc ctcttcatca atggccgtta
     2221 tatcaagaac ttcctgctca atcgtgctat tttggatggt ttcggaagca agcttatggt
     2281 tggacgtttt ccactggctg tcattcacat ccatatcgac ccttatctag cggatgtcaa
     2341 tgtgcatcca actaagcaag aggtgcggat ttccaaggaa aaagaactga tgaccctggt
     2401 ttcagaagct attgcaaata gtctcaagga acaaaccttg attccagatg ccttggaaaa
     2461 tcttgccaaa tcgaccgtgc gcaatcgtga gaaggtggag caaactattc tcccactcaa
     2521 agaaaatacg ctctactatg agaaaactga gccgtcaaga cctagtcaaa ctgaagtagc
     2581 tgattatcag gtagaattga ctgatgaagg gcaggatttg accctgtttg ccaaggaaac
     2641 cttggaccga ttgaccaagc cagcaaaact gcattttgca gagagaaagc ctgctaacta
     2701 cgaccagcta gaccatccag agttagatct tgctagcatc gataaggctt atgacaaact
     2761 ggagcgagaa gaagcatcca gcttcccaga gttggagttt ttcggacaaa tgcacgggac
     2821 ttatctcttt gcccaagggc gagatggact ttacatcata gatcagcacg ctgctcagga
     2881 acgggtcaag tacgaggagt accgtgaaag cattggcaat gttgaccaga gccagcagca
     2941 actcctagtg ccctatatct ttgaatttcc tgcggatgat gccctgcgtc tcaaggaaag
     3001 aatgcctctc ttagaggaag tgggcgtctt tctagcagag tacggagaaa atcaatttat
     3061 tctacgtgaa catcctattt ggatggcaga agaagagatt gaatcaggca tctatgagat
     3121 gtgcgacatg ctccttttga ccaaggaagt ttctatcaag aaataccgag cagagctggc
     3181 tatcatgatg tcttgcaagc gatctatcaa ggccaatcat cgtattgatg atcattcagc
     3241 tagacaactc ctctatcagc tttctcaatg tgacaatccc tataactgtc ctcacggacg
     3301 tcctgttttg gtgcatttta ccaagtcgga tatggaaaag atgttccgac gtattcagga
     3361 aaatcacacc agtctccgtg agttggggaa atattaaaag tataaaaaag tctgggaaaa
     3421 attttcaaaa tcagaaaaac gcataaaatc aggtgttcaa aaaccttgat tttatgcgtt
     3481 ttatcatgga aatagttact tcatgttttc ctaattcttt tcgaaactct ttttaaacca
     3541 cgtcagtttt atcagtaatc tcaaaacagt gttttgagct aattttgcca gttttgtctg
     3601 taacatcgaa gttgtgtttg accactctgc gactggtttc ctagtttgct ctatgatttt
     3661 cacagagtat taaattgcga ttttgccaag tttctttatt cgtctaaaag tagagtctgt
     3721 tctatgcgtc taatgtacga attaggttga ccatttcaat agctccttgt gcacactcag
     3781 aacccttatt tcctgcttta gtaccagctc gttctatggc ttgttcaatt gtatctgtcg
     3841 ttagcacacc aaacataaca ggaatttcgc tatttaaact gatttgggcg attcctttag
     3901 atacctcgct acatacataa tcataatgac ttgtattccc tctaatgaca gctcccaagc
     3961 agataattgc atcatatttt ttactttttg ccatttttga tgcaatcagt ggtatttcaa
     4021 aagctcctgg aacccaggct acctcgatat ctttctcgtt tacattctct cttttgagat
     4081 tatctagtgc tccagataat aattttgaag ttataaattc attaaatctc gctacaacaa
     4141 tacctatttt aatattgttt gctactaaat taccttcata agtgttcatt tatttttcct
     4201 ccatatttaa aatgtgaccc attcgatttt tctttgtttc taaataaaaa ctatcgtaag
     4261 gattggcttc tatttcgatt gatattctac tggaaatggt aattccatat ttttctaact
     4321 gttcaacctt gtcaggatta tttgtcagta aatgaagtga ctgaagtccc agatctttaa
     4381 gcatttgtgc tccaatatga tattctctta aatcaccttc aaagcctaat gcaagattgg
     4441 catcaagcgt atccatgcct tgatcttgta aatgataggc ttttaattta ttgataagtc
     4501 caattcctcg tccctcctgt cgcaagtaaa gtaagacacc cgaaccattc tcaacaatca
     4561 ttttcatagc tttatcgaat tgctgtccac aatcgcaacg taaagagcct aaaacatctc
     4621 ctgttaaaca ttcggagtgg acccgacata atacattggc ttcatcctct atgtttccca
     4681 taataagagc aagatgatgt tccccattta gtttatctat atagctaatt gctttgaaat
     4741 taccgtatct agtaggcata ttgacagttg aaactcgttc taccagctga tcatatactt
     4801 ttctatattc ttgtaattct ttgatggtaa ttagtggaat gttgtgtttc ttcgagaact
     4861 gaattaaatc atctgttctc atcattttgc catcatgatt cattatttca caacataggc
     4921 cacactcttt tagtccagct aattttaata aatcaacagt tgcttctgtg tgtccatttc
     4981 tttctagaac accacctttt tttgcaatta aaggaaacat gtgtcctggc ctgcgaaaat
     5041 cagagggtgt tatatcttca gctacacaca tacgtgcggt cagtcctctt tcctcggcag
     5101 aaatacctgt ggtcgtttct ttataatcaa ttgaaactgt aaaagcagtc ttatgattat
     5161 ctgtattgtt ttcaaccata ggtgaaagca ttaattgatt agctaaactt tcgctcatag
     5221 gcatacaaat taatcctttg gcataagtag ccataaaatt aacattttct gttgtagctg
     5281 cttgtgcaga acaaattaag tctccttcat tttctctatc cttgtcgtct ataacaagaa
     5341 caagtcgtcc cttctgcaat gcttctaatg cttcttgtat ttttcgatat tccattgact
     5401 gattatcctt tctgctaaaa tccattttga tataatagtt ccttcgatat ttctgatttt
     5461 ggagagttat ccatcagttt ttgcacatat ttacctaaga tatcattttc aagatttact
     5521 gtactcccga cttgtttact cttaagaatg gtttgtttca aggtatgagg gataacagat
     5581 actgaaaagt ttactttgga gactttagcg acagtcagac taatgccgtc aattgtaata
     5641 gatccttttt caactattaa atctaaaatt tctttttgtg tgttgatttg ataccataca
     5701 gcattatcat ctttttttat tgacgagatt tttcctgtac catcaatgtg tcctgtaacg
     5761 acgtgacccc caagtcgacc gttgacagat aaggctcttt ctagattcac ctcacttcca
     5821 tgttttaata gagtaagagc tgttcgactc catgtttcat tcattacatc aactgtaaag
     5881 gattgatgat tgaaatgagt aactgtaaga cagataccat ttactgctat actatcgcct
     5941 aaatggatat ccgttaatat ttttgaggct ttaattgata gtttacaatt acgagagtct
     6001 ttctgtattc tttcaacttt tccgatttct tcaattattc ctgtgaacat ggataaatca
     6061 cttcactttc tatgagatag tcatttccta tttgagaaaa agcataaggt ttcaatctaa
     6121 tagcgtcatt tggcaaagaa atgccttcac ctccgacagg aaacttggca ctgcctccaa
     6181 aaatttttgg tgcaatatat attttcagct catcaacaat ttgttgttcc aaagcactcc
     6241 aattcattag actgcccccc tctagaacta ggctatcaat ctgcatgttt cctagatgtt
     6301 gcattaaact cgataagtct atatgattgc cttttttctt tatggaaagt atttcacagc
     6361 catgattttg atatagcttc attttatttt tgtcttcaga ggaagtggca atgtaagttt
     6421 taatatcatt tgctgttttt acgattttag aggtaagagg agttcgtaaa tgtgtatcgc
     6481 atatgatacg gataggattt ttcccttcct ccaatctaca tgtcagcaaa ggatcgtctt
     6541 gaataacagt attgactccc accataattg cactaacata gtgtcgtaac tgatgcacat
     6601 gctttcttgc ttcttcttca gtaatccatt tggattgatt tgttttagtg gctatttttc
     6661 catccattga cattgcatat ttcataaaaa catagggtac atgctgggta atatactttc
     6721 taaaactttt tattaagtta agacactcat tttctaaaat tccaacagta acttgaagat
     6781 tattttcctc aagtatcttt actccttttc cagatacaat aggattacag tctaggcttc
     6841 caatgactac tcttgtaata ccactatcga ttatagcatc tatacaggga ggtgttttcc
     6901 cgaagtgaca acagggttca agtgttacat aaagcgtcgc tccgacaggg gattttctac
     6961 agtttttaag agcatttctc tcagcatgtg ggccaccaaa aaactcatga taaccttgtc
     7021 cgataatgtg attatctttt acaataattg cgccaaccat aggattggga ttgacgtaac
     7081 cagccccttt ttgtgccagt tttattgcta atttcatata ttttgaatcg ctcatctcac
     7141 tacctccaaa aaaatatacc ttgaataggg gactactcaa ggcatacaaa agaaaactta
     7201 tgcgattaac aaaaatgctc tgaaatgaca agtaatcatt tcagagcacg caaaaagcac
     7261 aaatatactt ttatcttctt tcatccagac tatactgtcg gctttggaat ttcaccaaat
     7321 catgcctttc ggctcgtggg ctataccacc ggtagggaat tgcaccctgc cctgaagata
     7381 gttattcaat tacagatgat tatagtactt aattttgaat atgtcaacag ataaatacag
     7441 attgtttttg atatactgta tttgtgataa tcgattctcg ctcctcggat aaagaaaata
     7501 tgatatacta gataaacgaa ataagagaga aggaacacta tgtacgcata tttaaaagga
     7561 atcattacca aaattactgc caaatacatt gttcttgaaa ccaatggtat tggttatatc
     7621 ctgcatgtgg ccaatcctta tgcctattca ggtcaggtta atcaggagga tcagatttat
     7681 gtgcatcagg ttgtgcgtga ggacgcccat ttgctttatg gatttcgctc agaggatgag
     7741 aaaaagctct ttcttagtct gatttcggtc tctgggattg gtcctgtatc agctcttgct
     7801 attatcgctg ctgatgacaa tgctggcttg gttcaagcca ttgaaaccaa gaacatcacc
     7861 tacttgacca agtttcctaa aattggcaag aaaacagccc agcagatggt gctggacttg
     7921 gaaggcaagg tagtagttgc aggagatgac cttcctgcca aggtcgcagt gcaagcaagt
     7981 gctgaaaacc aagaattgga agaagctatg gaagccatgt tggctctggg ctacaaggca
     8041 acagagctca agaaaatcaa gaaattcttt gaaggaacga cagatacagc tgagaactat
     8101 atcaagtcgg cccttaaaat gttggtcaaa taggagcaga gaatgacaaa acgttgttcg
     8161 tgggtcaaga tgaccaaccc gctctacatc gcctatcatg atgaggagtg gggtcagccc
     8221 ctccatgatg accaagcatt gtttgagttg ttgtgtatgg aaacctatca ggcaggcctg
     8281 tcttgggaaa cggtactcaa caaacgccaa gctttccgag aagcctttca tagctatcaa
     8341 attcactcag tcgcagagat gactgacact gaattggaag ccatgctgga gaatccagct
     8401 atcattcgaa atagagccaa gatttttgct acacgcgcta acgcccaagc ctttctacag
     8461 ttacaggcag agtacggctc ttttgatgcc tatctttggt cttttgttga ggggaaaact
     8521 gtcgttaacg atgttcctga ttatcgccaa gccccagcta aaacaccctt atctgagaaa
     8581 ttagccaaag atctcaaaaa acgaggcttc aagttcacag gcccagtcgc cgtattgtct
     8641 tttctacagg ctgcagggct agttgatgac cacgagaatg attgtgagtg gaaaggtctt
     8701 aaatgatgtc taacaaaaat aagggaattc tgatttttgt gattctctat acagtcctct
     8761 ttgtgtttga tggcgttaaa ttgctggctt ctttaatgcc atttgccatt gcaaattatc
     8821 ttgtttatgt agttttagct ttatatggct ccttcttgtt caaggataga ttgatccaac
     8881 aatggaagga gattagaaag actaaaagaa aattcttctt tggagtctta acaggatggc
     8941 tctttctcat tctgatgact gttgtctttg aatttgtatc agagatgttg aagcagtttg
     9001 tgggactaga tggacaaggt ctaaatcagt ctaatattca aagtaccttt caagaacaac
     9061 cactactgat agctgttttt gcttgtgtca ttggacctct ggtagaagaa ttatttttcc
     9121 gtcaggtctt attgcattac ttgcaggaac ggttgtcagg tttactaagc attattctgg
     9181 taggacttgt ttttgctctg actcatatgc acagtttggc tctatcagag tggattggtg
     9241 cagttggtta cttaggtgga ggccttgcct tttctattat ttatgtgaaa gaaaaagaga
     9301 atatctacta tcccctactt gttcacatgt taagcaacag cctctcctta atcattttag
     9361 ctatcagtat agtaaaatga aataagaaca ggacaaatcg atcaggacag tcaaatcgat
     9421 ttctaacaat gttttagaag tagaggtgta ctattctagt ttcaatttgc tgtaatatgt
     9481 gatgaaaatg ccagtaataa taccgagaaa aaagctgaga aacttttccc agctttattt
     9541 gttatagtca aagcgaatga cttgttcctg tgcatctaca tgagcatgaa ccccaaaggg
     9601 tacaattgct cttggagttg cgtggccgac attcagatta tagacaatcg ggatattgct
     9661 gtcaatgata tccaatagtg cctctttata gtcgtcatgg aaagtttcat ccataggttt
     9721 tccgaccaag agtccattga tgaccgcgaa tatgccagtg tcctttaaag ttagcaacat
     9781 ctttttgaag tcttctggtt taggcttttc ttcgcttgtt tcgagcaaga ggattttccc
     9841 ttcccagtct gacaagtcag ggaaaagttt gtatttttgg cagagttccg tgctatctgc
     9901 gtatcgagag ttgtcaaaga tatcgtagag ggattcgagg caaccaccga ggattttccc
     9961 ctcgaactga gcacttcctt gcaacaagtc aaaacctgta tttgtatgac tgacacgagg
    10021 tgttcccagg gctgtgggac taaaatcagt tcgttcctca taccaaacgt cactagggcg
    10081 gatttctgaa attcttcccg tcttaatcaa ttctttaaag tagtgaaggc tataggctag
    10141 catttctttg tctaattcac aaatgtctgc taaaaaggat tgaccataaa aagtcttgat
    10201 tcctaattta tgcaacatga ggtggttcat ggttgtatcc gagaagccaa gaaaaatttt
    10261 ttgcttgata accttttgga gttggtcatt ttcaaaaaga taaggtagca agcgataggt
    10321 atcgtctcca ccgatggcac ataggatcat gtcgatgcta tcatcagaaa aggcatgaat
    10381 caaatcctct gcacgagctt caggatggtc cttgataaag tctaatcctt ttaacgaatg
    10441 ggacaaaaag atgggattga gtcccagatg cttgagacgt tggataccca agtccacttc
    10501 gtgtttgaca aaatcctctc cgataatgcc actagataaa ctaacaatac caatagtaga
    10561 aaccatatct catcctccta gaaatagatt gagcctattt tatcacaaaa tataagagaa
    10621 agctatgtgg gatttcagaa gaatactttt aatactcttc gaaaatctct tcaaaccacg
    10681 tcagttttat ttgcaacctc aaagctgtgc tttgagcaac ctgcagctag cttcctagtt
    10741 tgctctttga ttttcattga gtataactca aaaaagtaag tgaaaaagca accgcacctg
    10801 cagttgcttt tatcgttttc ttattcttga tagcgtgttg gtcctgcact tgcactacgg
    10861 atattcaagc gtttcttgag atagaagcga agggctagga gggctgctcc aataatagct
    10921 agtggcaatg gatccagtac tgggttaagg ctagctggta ggaagcttgt tgcaaagaag
    10981 acaagcaacc aaaggaacat agaagctagg ataactagta cagatttcca gaaaggtgga
    11041 cgttgactgc ggtccatatc tggtccatag tattggtaaa caaagtagta catcaagtag
    11101 aaggcaaatc caccaaccag tccaactaat agaagagtaa tcaatccata gccgaaagct
    11161 tgatctgccg caaagaaggt tgtgagggcg ctgacaaggg caaagaggct agtgatgaaa
    11221 agagctgagt ccataatcat cagttttgga tcatcatttt cttttggatg ctctttttcg
    11281 tactgctctt tgacagtgaa gctatgagcc caatgagttg gtgcgccgta tagggaacgg
    11341 gcagttgtac ctttagattg ctcctcaagg atttggggaa tgacttcctc aaaaatagtc
    11401 tggatttcag cgtctgtttt cccatctttg atgaattgtt gggtagcaat gtggacaaac
    11461 tcttggtttt tcttagttaa tttttgtaga tcaatttgag acataggaac tcctcttaga
    11521 accatttttt atggatgaga tagagagtga gcgagacact catagcaaag gcgataaaga
    11581 cgattaacca gaaggcattt ggctctccgt ttagggggat ttcattatcc ttaaagttca
    11641 tcccgtaggc agaaaagacc atggttggga tggacatgac gatggtcaca agggccaagg
    11701 ttttcatgat gttgttctgg ttgttagaaa tgatagaggc aaaggtctct gtcatagaat
    11761 gcaagacgtt tccataaata tctgccatct cgatggcctg ttgggtttca atcagggtgt
    11821 cttcaagcag gtcttcgtcc tcaaggtatt tcttgatatt gctggttgaa ctggtcaatt
    11881 tcttaatcac gcgctcattt gttttgaggg aggccttgaa atagacgata gttttttcca
    11941 attccatgag ctcaatcaat tcttcattac gagttgattg atgcagttga ctttcgattt
    12001 gttcactctt gcggtcgatt gaacgaaggg ctgttaggta aagctctgca ttgcgataaa
    12061 gaatttgaaa gataaaacgt gaacgcatga aggtatagaa attacgcaat cgacggttga
    12121 taaagacatc aaggacaggt agtggttcca aacacgtagt gataatggtt tcctcagtga
    12181 tgataatacc aagcgggatg gttacgtagt aggtgcggtt atttctttcc tccgtgaccg
    12241 gcacgtctac gataatcagg gtatactcgt cttcaatggt aatacgagac atttcttccg
    12301 catcgagcgg tgctcgaagg tcggcaatat caatatcgaa ggtgttggcg atttcgagtg
    12361 attcattttg agtcggattg acgagattga tccaagtacc cggttcaagc gtatcgatct
    12421 ctttaaattc agttgttgta gagagaaaaa cttgtttcat atcccttatc ctttctcatt
    12481 tttcagattt tttcacactg tactattata ctacaaaatc ggccttttgg gtaatagaat
    12541 ctcacttttt ttggtataat ggtaagcaat aatggactag aaagaacaaa gatgcaagat
    12601 aaaattgtca ttcatggggc gcgtgcccat aatttaaaaa atattgatgt ggagattccg
    12661 cgagacaagt tggttgtcgt gactggcttg tcaggttcag ggaagtccag tctggctttt
    12721 gatactctct atgcggaggg acaacgtcgc tatgtagaga gtttgtccgc ctacgctcgt
    12781 cagttcttgg gaaatatgga aaaaccagat gtagatgcca ttgatggtct cagcccagct
    12841 atttccatcg accagaaaac gactagtaaa aatcctcgct cgacggtggg aacgacgact
    12901 gaaatcaatg actatctgcg tctcctctac gcacgtgtgg ggacgcctta ctgtatcaac
    12961 ggacatggag ctatcaaggc ttcttctgtg gagcaaatcg ttgataaggt tttggagtta
    13021 cctgaacgcc agcgcttgca gatcttggct cctgtcatcc gcaagaaaaa aggccaacat
    13081 aagagtgtta tcgagaaggt tcagaaagac gggtatgttc gtgttcgtgt ggatggggaa
    13141 gtctatgatg tgaccgaagt gccagagttg tctaagagca agcaacacaa tatcgatgtc
    13201 gtggttgacc gtattgttat caaggagggc attcgtagtc gtctctttga ttccattgag
    13261 gctgcccttc gtattgcaga aggttatgtc attatcgaca ccatggacga ttcggagttg
    13321 ctcttctctg agcattatgc ctgtccagtt tgtggtttta ctgtcccaga gttagagcct
    13381 cgtctcttct ctttcaatgc tccttttggc tcttgtagtg agtgtgacgg cttgggcatc
    13441 aagctggagg tggatactga tttggtagtg ccagatgcca gcaaaacctt acgtgaggga
    13501 gcgctagcac cttggaatcc tatctcatcc aactactatc caaacatgtt agagcaggcc
    13561 atgaaagtct ttggagtggc tatggataag ccttttgagg acctgtcaga agaagataag
    13621 aacttgattc tctatgggtc agatggtaag gaattccatt tccactatga gaatgaattt
    13681 ggtggcgtgc gcgatatcga cattccgttt gagggagtta tcaataatat caaacgtcgt
    13741 taccatgaaa ccaatagcga ttacactcgc actcagatgc gtctctacat gaatgagctg
    13801 acctgcggaa cctgtcaagg ctatcgtctc aatgaccagg ccttgtctgt ccgtgtgggc
    13861 ggccagcaag ggccacatat tggagaaatc tcagacctgt ctatcgctga ccacttggac
    13921 ttggtgagcc agttaacttt gtctgaaaat gaagccatca ttgctcgtcc cattctcaag
    13981 gaaatcaagg atcgtttgac cttccttaat aatgtgggtc ttaactatct aaccctgtca
    14041 cgttcagcag gaaccctttc aggtggggaa agtcagcgca ttcgtttggc aacccagatt
    14101 ggttccaacc tatcaggcgt cctctatatc ctagacgagc cgtcaatcgg tcttcaccag
    14161 agggacaatg accgcctgat tgccagtctg aaaaagatgc gtgacttggg caatactctt
    14221 atcgtggtgg aacacgacga agataccatg cgtgaggctg attatctgat tgacgttggt
    14281 cctggtgccg gtgtttttgg tggtgagatt gttgcagcag gtacacctaa gcaagtggct
    14341 cgcaacagca agtctatcac aggtcagtac ttgtcaggca aacgtgtcat cccagtacca
    14401 gaagagcgcc gtgtcggaaa tggtcgtttt attgaagtga taggagcgcg tgagaacaac
    14461 ttgcaaaatg tcacggctcg ctttccacta ggaaaattta tcgcagtgac aggtgtgtcg
    14521 ggttcaggga aatcgactct aatcaacagc attctcaaaa aagccattgc ccagaagctc
    14581 aaccgtaatt cagacaaacc tggtaagttt aagactatta cagggattga gcatgtcgac
    14641 cgtttgattg atattgacca gagccctatc ggacggacgc cgaggtctaa cccagctacc
    14701 tatacaggag tttttgatga tatacgtgac ctttttgctc agacaaatga agccaagatt
    14761 cgaggctaca agaaggggcg cttcagtttc aacgtcaagg gaggtcgctg tgaagcttgc
    14821 tcaggtgacg ggattatcaa gattgagatg cacttcttgc cagatgttta tgtggcttgt
    14881 gaagtttgcc acggaacccg ctataacagt gaaaccctag aagttcacta caaggaaaag
    14941 aatatttcgc aggtcttgga tatgacggtc aacgatgcgg tagaattttt ccaacacatt
    15001 ccgaaaattc aacgcaaact ccagaccatc aaggatgtag gtctaggcta tgtgaccttg
    15061 ggacagccag ctaccaccct ttctggggga gaagcccaac gtatgaagtt agctagcgaa
    15121 ctccacaaac gctcgacagg aaaatctttc tacattctgg atgagccgac gacagggctt
    15181 catacagagg acattgctcg cctgctcaag gttttagctc gctttgtaga cgatggcaat
    15241 acagtcctcg tcatcgagca caatctggat gttatcaaga cggcagacca tatcattgac
    15301 ttgggacctg agggcggtgt cggtggtgga accatcatcg taacaggaac tccagaagaa
    15361 gtagctgcca acgaagccag ctatacagga cactatttga aaggaaagtt acatcatgga
    15421 taaacgcgta caagcatttc tagctaaaat gcaagaaaaa gaactagatg gtatcatcat
    15481 caacaatctt aaaaacgtct attatttgac tggtttttgg ggctcaaacg gaacagtctt
    15541 tatcagccgt gaccgtcagg tcttagtgac agactctcgc tatatcatcg cagctaagca
    15601 agaaaccagt ggttttgaga ttgtggctga tcgtgatgaa ttggctgtca ttgcaggaat
    15661 tgttaaggac atgggcttga ctcgtatcgg ttttgaagat gagatttcag tgtcttatta
    15721 ccaccgtatg caggcagctt ttgcaggttt ggacttgctt ccacaaactc agtttgtgga
    15781 aggtcttcgt atgattaagg atgaggcaga gattgcagcg attcgcaagg cttgttctat
    15841 ctcagaccaa gctttccgcg atgcgcttga ctttatcaaa ccaggaaaaa ctgaaattga
    15901 gattgccaac ttccttgatt tccgcatgcg tgagttggga gcatctggct tatcttttga
    15961 tacgatccta gctagcggta tcaattcttc taaaccccat gcccatccaa tgcacaaacc
    16021 agtggagttg ggagaagcca ttaccatgga cttcggctgt ctctatgacc actatgtcag
    16081 tgatatgacc cggactatct atctagggca tgttagcgat gagcaggcag agatttacaa
    16141 tacggttcta aaagctaacc aagccttgat tgaccaagct aaggcaggct taggtttccg
    16201 tgactttgac aaaatccctc gtgatattat cattgaggca ggttatggtg actactttac
    16261 tcacggcatt ggccacggta ttggtctgga tatccatgag gaaccctact ttagccagac
    16321 ttctacagaa actattaaga caggtatggc cttgaccgat gaaccaggta tctatatcga
    16381 aggcaaatat ggcgttcgta tcgaggatga tatcctgatt acagagacag gttgtgaatt
    16441 attgacccta gctccaaaag agttgatagt catttagttg tttgtcaaga aaaaagtacg
    16501 aaaatgacga aaaaagtcaa aaaaaattaa aaatgaaagt tctataatga agttagccac
    16561 cttaccttag tcaagaatta gatgtttcac tatgtttgag taagttgatg atttcatttg
    16621 ataacaggtt tgaaactgtt aggctaggtg gccaaggcta atcatagcct tggtttagct
    16681 gaaaaaacag gttcaagggt tcctgttgtc aaatgaaatg tgatttaagg tataagaaaa
    16741 cacctctgtg ctatacttgt tgttcaccac aaacacaagg aaaggcacag agatgcaaga
    16801 acattatacc ccaaaaggga aacatttgac aatagataac cgtcgcttga ttgagcggtg
    16861 gaagaat
//
LOCUS       DAVKMO010000043        16468 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVKMO010000043 DAVKMO010000000
VERSION     DAVKMO010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16468
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.043"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(98..2356)
                     /locus_tag="VW361_001560"
     CDS             complement(98..2356)
                     /locus_tag="VW361_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9744570.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAAVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPNEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VW361_001561"
     CDS             complement(2585..2815)
                     /locus_tag="VW361_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU9744571.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VW361_001562"
     CDS             3005..3688
                     /locus_tag="VW361_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9744572.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQCS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VW361_001563"
     CDS             3688..4422
                     /locus_tag="VW361_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9744573.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVPDRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VW361_001564"
     CDS             4576..5433
                     /locus_tag="VW361_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU9744574.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VW361_001565"
     CDS             5575..6447
                     /locus_tag="VW361_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU9744575.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VW361_001566"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VW361_001566"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU9744576.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VW361_001567"
     CDS             7426..8637
                     /locus_tag="VW361_001567"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU9744577.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VW361_001568"
     CDS             8639..9181
                     /locus_tag="VW361_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEU9744578.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9197..10006
                     /locus_tag="VW361_001569"
     CDS             9197..10006
                     /locus_tag="VW361_001569"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9744579.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRTYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10503..11525
                     /locus_tag="VW361_001570"
     CDS             10503..11525
                     /locus_tag="VW361_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HEU9744580.1"
                     /translation="MKESENDAPKLETPLREEPRLAPQTLLEASEVLENKREESKVGI
                     TEPAQDSPILAPVEETKEEAVTEKPTNTRSLTAEDLVKISKGELHLENDLIDESFYGE
                     KALDLEGDDYQDGIKNKDGKDYLGYNSHPLLADSDGDGLADGEDDNKKEWYVTDRDSL
                     LFMELAYRDDDYIEKILDHKNLFPSLYLDRQEHKLMHNELAPFWKMKKAYYTDSGLDA
                     FLFETKSDLPYLKDGTVHMLAIRGTRVNDAKDLSADFVLLGGNKLAQADDIRKVVGEL
                     AKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDFYNHVLRKVTTFSAPKVITSRTVW
                     DAKNGF"
     gene            11535..12110
                     /locus_tag="VW361_001571"
     CDS             11535..12110
                     /locus_tag="VW361_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000445853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU9744581.1"
                     /translation="MESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKH
                     RSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPQSSSQPSAEPME
                     NIALGKQVTQSSTAFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIR
                     QINIYNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            12135..12647
                     /locus_tag="VW361_001572"
     CDS             12135..12647
                     /locus_tag="VW361_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU9744582.1"
                     /translation="MSAQITINHKKARYFRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLIIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13301..14011
                     /gene="deoD"
                     /locus_tag="VW361_001573"
     CDS             13301..14011
                     /gene="deoD"
                     /locus_tag="VW361_001573"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9744583.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(14034..14558)
                     /locus_tag="VW361_001574"
     CDS             complement(14034..14558)
                     /locus_tag="VW361_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU9744584.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14611..14847)
                     /locus_tag="VW361_001575"
     CDS             complement(14611..14847)
                     /locus_tag="VW361_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU9744585.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14915..15835)
                     /locus_tag="VW361_001576"
     CDS             complement(14915..15835)
                     /locus_tag="VW361_001576"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU9744586.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            16025..16429
                     /locus_tag="VW361_001577"
     CDS             16025..16429
                     /locus_tag="VW361_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744587.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFICSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
BASE COUNT         4868 a         2970 c         3659 g         4971 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgtttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttgaccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt cgtccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacagcgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa tgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcagt caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccac ttttatttgc
     3601 agcattttac tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggcatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag gttatctttg agggagtcga tattacggac
     3901 aagaagaatg acctgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gattgaaaat attaccttgt cacctatcaa gaccaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtgccaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa ccgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttgttgta taataaaagt gagagggaaa aaggatgaaa
     5581 gtgattaatc aaaccttact agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagtta tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagat
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaaaga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa tcatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggagctt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 tagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctggg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca gaagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt gggtcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caaggtcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 taggacctac acaccagaat accgtgccac tgcccatgaa gtagctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccggattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagtggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagtaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttcttag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactggctcc tcaaacgctt ctggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtagg gataacagag ccagctcaag actcacctat tcttgctcct gtagaagaaa
    10681 ctaaagaaga agctgtgaca gaaaaaccaa caaatactcg ttctctaact gcagaagatt
    10741 tggtgaagat ttccaaaggg gaattgcatt tagaaaatga tttgattgat gaatctttct
    10801 atggtgaaaa agctcttgat ttggaagggg atgattacca ggatggcatc aaaaacaaag
    10861 atggtaagga ttatctagga tataacagtc atcccttgct agcagacagt gatggggatg
    10921 gtttggcaga tggggaagat gataataaga aagaatggta tgtcacagac cgtgattctc
    10981 ttctctttat ggagttagct tatcgagacg atgattatat tgagaaaatt ttagatcata
    11041 agaatctttt ccctagtctc tatcttgacc gtcaagaaca caaactcatg cacaatgaat
    11101 tggctccttt ctggaagatg aaaaaagcct actatacaga tagtggcttg gatgctttct
    11161 tatttgagac caagagcgac cttccttatc tcaaagatgg aacggtgcac atgttggcta
    11221 ttcgtggaac gcgagttaat gacgccaagg acttgagtgc agattttgtt ttattaggtg
    11281 gaaataaact agctcaagcg gatgatatcc gcaaggttgt tggggaatta gccaaggata
    11341 taagtattac taagttgtat atgacaggtc attctcttgg aggctaccta gctcagattg
    11401 cagcggttga agattaccaa aaatatcctg atttttataa ccatgtattg aggaaagtga
    11461 caactttcag tgctcctaaa gtcattactt ccagaactgt ttgggatgct aagaatggtt
    11521 tctgagatgt tggtttggaa agtcgtaaat tagctgttag tggaaaaatt aagcattatg
    11581 tggttgataa tgacaatgtt gtgactccct tgattcataa taatcgtgat attgttacat
    11641 ttacaggtaa ttcacgcttt aaacaccgtt ctcgtggcta ttttgaaagt ccaatgaatg
    11701 atattcctaa ctttaatatt ggtaaacaag ctaccttgga taaacatggt tatcgtgatc
    11761 cgaaattgga taaagtgcga ttctttaaga aacaggctct acctcaatct tctagtcaac
    11821 caagcgctga accaatggaa aatattgcct taggaaaaca ggttactcaa agttcgacag
    11881 ctttcggagg agatgctaga agagctgtgg atggcaaagt cgatggtaac tatggtcaca
    11941 attctgtcac tcatacaaac ttccaatcta agccttggtg gcaagtagat ttggctaaag
    12001 aagaaaccat tcgccaaatc aatatttaca accgaacaga cactgcccag gatagattgg
    12061 caaactttga tgtcattctt ttagacagtt ctggtaaaga aattgagtga aaacgtataa
    12121 tatctcctaa agatgtgtca gcacaaatta cgattaacca taaaaaagcg cgctattttc
    12181 ggattgagct agaaggctat aatgccctca gtcttgcaga agttgaagtt ttccgcttta
    12241 tagctacgaa tgctgaaacg gcgacacaag tttctaagcc agttcaacca atcagtcaga
    12301 ctcctgtgaa agataaaaca ttgataattc aacacagtgg agcttacatt gcccgctact
    12361 ccataacttg ggaagaagtt ccagtagata aagatggaaa ccaagttgtt cgtagtcatt
    12421 cttgggaagg aaacggtcgc aaccagactg caggttttgt cctcaacctc ccaatcaaag
    12481 aaaatatgag aaatctgcga gttaagattg agaaaaagac gggcctacta tggaatagat
    12541 ggcaaacaat ctatgaaaac agaccaattt tagctcaacc ccaccgtaaa attacccatt
    12601 ggggtacgac attgaattcc aaggtgagtg acgatgatgt cttgtaatct gatggtagaa
    12661 tgacagttag tttgtctagt ttataagaaa gtactacctg agcttgaata gaactcaggt
    12721 agctctctat gaaagaacaa aattaatact caatgaaaat caaagagcaa actaggaaac
    12781 tagccgcagg ttgctcaaag cactgctttg aggttgtaga taagactgac gaagtcagtc
    12841 acatatataa tccaaggcga cgttgacgtg gtttgaagag attttagaag agtataaaca
    12901 gaaaggtaga gcgcgtgttc taatttgaac acgagtagaa aacttttcta aaagcaaaaa
    12961 cgaaaggatg ggtaaactgt attcgctgaa ctgaatacgg gcgactctcc tctaaatcaa
    13021 aattaagaaa ggaattgacc ccaccctaaa agtagtggga aaaagatagt tggtctagcg
    13081 agcatcgctc actgcgccca actcctattt tcccttcgct ttttgatggg tttggtatct
    13141 ttctcaatat aaaatataaa ataaagaaag atagagcgtg tgttttgatt tgaacacgag
    13201 cggaaaactc ggaaaataga taatctgact gaaaaatcag gatttctcgt caggttccta
    13261 attttcagtc gttttcttct cgctctttgt atcataaatt atgtctatcc atattgctgc
    13321 tcagcagggt gaaattgctg ataaaattct tcttcctggg gatcctcttc gtgctaagtt
    13381 tattgcggag aatttccttg atgatgctgt ttgttttaac gaagtgcgta acatgtttgg
    13441 ttacactggt acttacaagg gtcactgtgt atctgtcatg ggaactggga tgggaatgcc
    13501 atctatttcg atttatgcgc gtgagttaat cgtagactac ggtgtgaaga aattgattcg
    13561 tgtgggaact gcaggttctt tgaatgaaga ggttcatgtt cgtgaattag ttttggcgca
    13621 ggcggctgca accaactcaa acatcgttcg taatgactgg ccacagtacg attttccaca
    13681 aattgctagc tttgatttgc ttgataaagc ttaccatatc gccaaaaaac ttggtatgac
    13741 tactcacgtt gggaacgttt tgtcatctga tgtcttttac tcaaattact ttgaaaagaa
    13801 tatcgagctt ggtaaatggg gagtcaaggc tgtggaaatg gaagcagcag ctctttacta
    13861 tcttgctgcc caataccatg ttgatgcgct agctatcatg accatctctg atagcttggt
    13921 caatccagac gaagacacaa ctgcagaaga acgtcaaaat accttcactg atatgatgaa
    13981 ggttggtttg gaaaccttga ttgcagaata attatagcca aaaaggaagc cctttatgaa
    14041 ttgtaggact tccttttctt atccagaaat tgatctagct ctctctgatt tcgaagaata
    14101 gtgactttat gtgaatattc ttggcaaagt ttttggtaat tttctttttg agttttgcta
    14161 cgcccatccc aaagaatcca tctgataaac tcccactcaa agcgttcagg gcaatctgcc
    14221 gccatacttt ctctgacttt tccacggtat ttaagataac gcttaaaggc tctaaagaga
    14281 caggtcaatg gcgaaaaatt gagaaagatg atttggtcag cttcttgcat tcgttcttgg
    14341 tagtagcacc aagaataatt accatcgatg acccaagctt tatgcttggt gagaaagttt
    14401 tttatctcgg ttaacatcca ttcgcagtca ctgtcttgcc aaccaggttg aaattggagt
    14461 gtgtccatgt gcagttttgg aatggagtag tagttagata acttttctgc tagagttgac
    14521 ttaccagaac cagaatatcc gataattgcg attttcattt tctacctttt cctatttgga
    14581 gacaaaaaaa cagcctctat ggactgtttc ttatttagca agtttagctg aaagacgagc
    14641 tttatcgcgg cttgctttgt ttttgtgaat caaaccttta gtttctgctt tatcgatagc
    14701 tgagctagca gcacggaaaa gttcttcaga tgggtttgct tcgaaagctt ttatagcagt
    14761 acgcatagct gatttttgag ctgagttctt ttcgttttgt ttaacgttca attcagcgcg
    14821 tttgatagct gatttaatgt ttgccaatgt tcttacctcc atatttacta actataccat
    14881 tatatatgaa aacttacgtt ttgacaaggg aaaattactt ttttaagtaa atttcatcga
    14941 tttcatggtt cttgctttta tgaagaatca cttctgcacg atttctggtt ggttcaatat
    15001 aattttgcag atttgtgaga ttgatactgg tccagacctg atgggcaaag gactccactt
    15061 ccccaatcgg catctgagta aaacgataat agtagctatc agggtcgttt tgggctaggc
    15121 tcagcatttt caagaaacgg tccagatacc aactttcaat atcatccact ccagcatcta
    15181 catagatgga aaagtcaaag aagtcagtga tatagagacg atcgttttgt ggattttgaa
    15241 agacattaat tccctcaaca attacaaaat cagcagcttt gacactttgt ttcttttcgg
    15301 gtacgatgtc gtaaacttca tgagaataga caggaatatc tacatcttgt ccatttttga
    15361 tgcggtccaa gaagttgaga agagcttcca tatcatagct ttcaggaaat cctttacgat
    15421 ttaaaatccc ctgctcaatc aaggtttgat tgggatagag aaaaccatca gttgtaacca
    15481 actcaaccgt agcatctgta aacgtacggg acagtaggat ttgaagtagg cgactggttg
    15541 tggattttcc aacggcaaca ctcccagaaa ccccaataat aaaaggttga gatttacttt
    15601 cacgttggag gaaaattcct tttgaaaagg ctaaatcttc cttagttcgc ttgtaaatct
    15661 gaatcagatg agccaagggg agatagatat ctgtaacgtc ttggagactg atttggtcat
    15721 taaaactctt gatagattcc aattcttctt ctgtcaaagg aggtgttgtc tttcgatgta
    15781 aagattgcca agtctggcgg ctgatttttt caaaatgtaa aaattcgttg gtcatttgtt
    15841 ttcccctaga tattttgtct atcataccat aaaaagctaa aaaaataaag cggtttcttg
    15901 aatgtggtaa gtcaatggta tatagtataa gtgatcaatt tattgatgaa ataggagata
    15961 gattctactg atttataagc ttataaaggg ggctttttag ttcacaactt ataggaggtg
    16021 tactatgaaa atcttaaaac gttacatatt ggaactctgt tttattttaa gttttgcttt
    16081 accttttata aaaggagcca atgcagataa tggtagatgc tttgtggaaa cctattacgg
    16141 ttttactttt ttgatggaac atgctattgt aacagctgtc tttatctgtt cgttcttaat
    16201 tgctttctta ctaaaaaaac gatgggcgaa atggattgct gctggtagtt attgcttttt
    16261 agtcctatgg attgcgacag agggttattt cttccgcatg tcactagaag atttgatacg
    16321 actttggaca agtttggaaa tcctgacaca aacgtatcag ttgggctttt atctaaacat
    16381 tttgttagga attttgttga taataaagta ttttaaggtt aagcaataga aataataatc
    16441 tgcctgatta tagatgataa actttttg
//
LOCUS       DAVKMO010000044        16098 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVKMO010000044 DAVKMO010000000
VERSION     DAVKMO010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16098
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.044"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            60..527
                     /locus_tag="VW361_001578"
     CDS             60..527
                     /locus_tag="VW361_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9744588.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(524..1039)
                     /locus_tag="VW361_001579"
     CDS             complement(524..1039)
                     /locus_tag="VW361_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU9744589.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(1051..1578)
                     /locus_tag="VW361_001580"
     CDS             complement(1051..1578)
                     /locus_tag="VW361_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9744590.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(1860..2423)
                     /locus_tag="VW361_001581"
     CDS             complement(1860..2423)
                     /locus_tag="VW361_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9744591.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(2407..2958)
                     /gene="coaC"
                     /locus_tag="VW361_001582"
     CDS             complement(2407..2958)
                     /gene="coaC"
                     /locus_tag="VW361_001582"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU9744592.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLITPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(2970..3659)
                     /gene="coaB"
                     /locus_tag="VW361_001583"
     CDS             complement(2970..3659)
                     /gene="coaB"
                     /locus_tag="VW361_001583"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU9744593.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLFAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISTDQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            3889..5559
                     /locus_tag="VW361_001584"
     CDS             3889..5559
                     /locus_tag="VW361_001584"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU9744594.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAAL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            5888..7063
                     /gene="mutY"
                     /locus_tag="VW361_001585"
     CDS             5888..7063
                     /gene="mutY"
                     /locus_tag="VW361_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU9744595.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            7118..7822
                     /locus_tag="VW361_001586"
     CDS             7118..7822
                     /locus_tag="VW361_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9744596.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            7815..9164
                     /gene="vicK"
                     /locus_tag="VW361_001587"
     CDS             7815..9164
                     /gene="vicK"
                     /locus_tag="VW361_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU9744597.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            9166..9975
                     /locus_tag="VW361_001588"
     CDS             9166..9975
                     /locus_tag="VW361_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9744598.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            10066..10308
                     /locus_tag="VW361_001589"
     CDS             10066..10308
                     /locus_tag="VW361_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU9744599.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            10310..10564
                     /locus_tag="VW361_001590"
     CDS             10310..10564
                     /locus_tag="VW361_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU9744600.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQINVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            10611..11306
                     /locus_tag="VW361_001591"
     CDS             10611..11306
                     /locus_tag="VW361_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEU9744601.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIILVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLLGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSS"
     gene            complement(11655..12641)
                     /locus_tag="VW361_001592"
     CDS             complement(11655..12641)
                     /locus_tag="VW361_001592"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU9744602.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALSFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            12835..15303
                     /gene="gyrA"
                     /locus_tag="VW361_001593"
     CDS             12835..15303
                     /gene="gyrA"
                     /locus_tag="VW361_001593"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU9744603.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQTQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLVITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            15303..16049
                     /gene="srtA"
                     /locus_tag="VW361_001594"
     CDS             15303..16049
                     /gene="srtA"
                     /locus_tag="VW361_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU9744604.1"
                     /translation="MSQKKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIV
                     WNTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIP
                     ELEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDN
                     AKNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERII
                     VKGDLKETKDYSQTSNEILTAFNQPYKQFY"
BASE COUNT         4944 a         2807 c         3561 g         4786 t
ORIGIN      
        1 aagataatat ctctggtagt aagtctgaaa atttaataaa ttagaaagcg agtaaattta
       61 tgtcccgttc ccaattaaca attttaacaa atatctgtct gattgaagac ctcgaaactc
      121 agcgcgtggt gatgcagtat cgcgcccctg aaaacaatcg ctggtctggt tatgcctttc
      181 ctggaggtca tgtagaaaat gatgaggctt ttgcggagtc tgtcattcgt gaaatctacg
      241 aagaaacagg gttgactatc caaaatcctc aacttgtcgg cattaaaaat tggccactag
      301 atacaggtgg gcgctatatt gtcatttgtt ataaggcgac tgagttctct ggtacccttc
      361 aatcttcaga agagggagaa gtttcttggg tgcaaaaaga ccagattcca aacttaaatc
      421 tggcctatga tatgctacca ttgatggaaa tgatggaagc tcccgacaag tcagagtttt
      481 tctatcctcg ccgtacagaa gacgattggg aaaagaaaat cttctagtct tttactaaat
      541 aacctagctg atccaaggcc tcctcgatat agtggaggtc ttgttgtgtt tcggcttcga
      601 ctaggtggta atggatgcca tctgtcaatt cagatagagg tctaaagtca gaatgctcga
      661 cttgttctag aaaatgttgc acatctctgc gacaagacag tttaagcaag gtttcaattt
      721 ctccataaac gggatggtca atcaaggtat tctggacatg cccgccatta tcgacaatag
      781 caaggagttc ctgaccgatt tcttcaactt catgtttcac tttgaaaagt ttgtgaacat
      841 aaggattggt atcaatttgc ttatagatgt agccacgatt ggtggatagg ataggagcgc
      901 catcggctct caaaattgca atgtcctgca caatgacctg acgtgtgaca tgaaaatgtt
      961 ccgccaaact ttggccatta agggctttag gagcttcttt caagagttgg agcagggctt
     1021 gtttgcgatc ttttgtcata gcttttcctt ttaacggcgt tttcgaagca ctttatagac
     1081 agctagtgct aatgtatagt ctaccatact atggataatt gtgccaaatc caactagtac
     1141 aaatagaaca tagaacatgt tttctacatt ggtacccgaa gttgcgtaaa aaaggacaca
     1201 ggctaatact tcagcaaggg catgaacaac agccaaaaca aagttgaaaa cccaggaaga
     1261 ttttggttta tctagggtat cggggaattt ttgtaggtaa agagctccta aagcaccaaa
     1321 agatatatgg gaaaaagccc gaaaaacgat aaccatggga tagccagcca tcaaaaatcc
     1381 aaaactagag gctaggatga caaaaactgc catcaagggc gacaagaaca tggctataaa
     1441 aatagcgatg tggctcccca aagtatagga agcaggtgga atgacaatct tgaaaggcat
     1501 aacaattgga atcaaaatcg caatagccgt taaaagggct gtcattgtca taaattgtgt
     1561 ctttttccgt gtattcacaa gaatctcctt tttaactgca tatacactag tatggtacaa
     1621 taaaccagac aataaagcaa gaatttactt gggtttatag atcatttttt agttaaaagt
     1681 tatagtagat tgaaactaga atagtccacc tctacttcta aaacattgtt agaaatcgat
     1741 ttggctgtcc tgatcgattt gtcctgttct tatttcgttt tactatagta aagatttcat
     1801 taaaaagaaa ctgtatagag caaaatctcc accttcaggt ttgaaagcgg agattgtttt
     1861 tattttttca aggtttgtag tcgtggaaca atggctaggg ttagaattgc agaaatgacc
     1921 aattcagcaa ttgaatttgt tgagataacg gttgccagaa gaagttggat atttccatta
     1981 taaacatttc caaataggaa gaagattcct ccaaggacaa agatagtatt tgtcaaggaa
     2041 ccaagggccc cagctaaaat cagaccagtc ttgtttttca tcagtttata gactaagtaa
     2101 ggagttaaac caatcaaaat acgtgggaca atggcaatga tagctgagta gatgtttccg
     2161 tttggtacga agggagagaa gaggtagctt gtcggtagaa tcgtaatcgt gttaaccgtc
     2221 aagctaagta atcccatcaa aaatccaagt gtaaccccaa ctcgtggacc ataaataatg
     2281 ctggcaataa tgacaggaat atgaacaatg gtcggtttga ttggaaatgg aaaaaggtta
     2341 aagataagtg agctcagaaa gtgtatcacg agcatggtag caaaaaagat agcaatgggt
     2401 gcaatattag agcgtttttt catcgatagt ttcctttatt ctttctaaaa taattgtgag
     2461 gtcagctaaa gctcctcgtc cgtggtctcc acaagctagt agggattcct taggagcaat
     2521 cagctgatag ccgtaggttt ctaatgtttt cagattattc tgagttactg gatggtcata
     2581 catttttgta ttcatagcag gagttattag tttgggaata tgacttggta gggctagagc
     2641 tgtactggtt accatgttgt ccgcaaatcc gtgagctagt tttgcaatag tgttagcagt
     2701 tgcaggtacc acgataaata aatctgcttt ttttccaagt tcgatatgat tgacctgatc
     2761 aggatagggt tccttcatga catccaagtg gacaggattc tgtgagagta cctgtagtgt
     2821 caaaggttgg ataaactctg tagcagcctg agtcattaag acagtgactt gatggccttg
     2881 tttttttaga gaactgacta aatctgccga cttataagag gcgattgaac ccgttacagc
     2941 caagagaatg tttgccatag ttttcctttc taagaatgat aggcttgaat tttttcaagg
     3001 aggagttctg caatttcttc tttagtctgg actgtttgaa gctgattttt ctcaacaaat
     3061 atagctcggt gctgatctgt tgaaatttga gtcaggtcat tcgcgatgat taaatctgct
     3121 tgattcttga taagactttt tcgtgcaatg tcaaccagat gatcttcggt aacatcaacc
     3181 agcagtttga aaccaatcag atgaatagta ggattccatt ccttgactag ggatatgatt
     3241 ttgggtgtct ttttaaggaa caaaacctga acctcatcag ttgaagaaat cttggcctga
     3301 tgattctgct tgcttaaaaa ttcttttaga ttggagctag cctgaacttc ctcaagccct
     3361 gtcatataaa caggagtgta gtcagaaaca gccattgagt ggatcaagac ctgataatcc
     3421 tgaacacgtt cttgcatttc tattagaagg tccttggtat tggtaatttc tcgaatactt
     3481 aggttaggat gaggctctgg cttcagagct cgttttgtcg taattaaaca aacttcatgc
     3541 cctgcaaaaa gcaaagtctc tgtgataatt ttccccaagt gacctgtaga atggttagtg
     3601 atagagcgga cgctatcgat agcttcactg gtaccgcccg atgtaactaa aattttcata
     3661 gcactattgt acacaaaaat aagcggtaag taaaatgaaa gtgataaatt tttggtaaaa
     3721 acgaagattt attatagttt caaactataa agccataaaa aatttaagaa aggactctaa
     3781 aagtcttaaa aacagagata tttacgaacg tttagagagt tttaggatgt taaaaatctt
     3841 gttttgtgat ataatgaatt atcatataag aggttagagg aattttgaat gaaaacagat
     3901 attgaaatcg cacagagtat tgagttgaag ccaattgttg atgttgtaga gaaacttggt
     3961 atttcttacg acgatttgga gttgtacgga aagtacaagg ctaaactcag ctttgataaa
     4021 attcgtgcag ttgagagcaa tccagtcggt aaattgatct tggttactgc catcaaccca
     4081 acacctgcag gtgaaggaaa gtcgacgctt accattggtc ttgcggatgc cttgaacaag
     4141 attggcaaga aaaccatgat tgctatccgc gaaccgtctc ttggtccagt catggggatc
     4201 aagggtggtg ctgctggtgg tgggtatgca caagttctgc caatggaaga catcaacctc
     4261 cactttactg gagatatgca tgctattaca actgccaaca atgccctttc tgccttgatt
     4321 gacaaccact tgcaccaagg gaatgagctg ggaattgatc aacgtcgtat cctctggaaa
     4381 cgcgttgtgg acttgaacga ccgtgcgctc cgccatgtga ctgttggtct tggtggtcct
     4441 ctaaacggta ttccacgtga ggatggtttt gatattacag ttgcttcaga aatcatggca
     4501 attctttgct tggcaacgga catcgaggac ttgaaacgtc gtttggcgaa tatcgttatt
     4561 ggttatcgct atgaccgtac gcctgtttct gtaggtgatt tgcaggttga gggtgccttg
     4621 gctttgattt tgaaggatgc tattaagcca aacttggttc agacaattta cggtacacct
     4681 gcctttgtac acggtggtcc atttgccaat atcgctcatg gctgtaactc tgttttggcg
     4741 acgacaacag cccttcactt ggctgattac actgttactg aagctggttt tggtgcggac
     4801 cttggtgctg agaaattcct tgatatcaag acaccaaact tgccaacatc tccagatgca
     4861 gttgttattg tcgcaaccct tcgtgccctt aagatgaatg gtggtgtggc taaagacgct
     4921 ctgactgaag aaaatgtaga ggcagttcgt gcaggttttg ctaacttgaa acgccacgtt
     4981 gaaaatatcc gtaagttcgg tattccagca gttgtagcta ttaacgaatt tgtatctgat
     5041 acagaagctg aaattgcagc cttaaaagaa ctctgtgcct caatcgatgt accagttgaa
     5101 ttggctagtg tctgggctga tggagcagaa ggtggagtag cacttgccga aacagttgtt
     5161 aagacaattg ctgaaaatcc agctaactat aaacgtttgt acgataatga cctttctgtc
     5221 caagaaaaga ttgaaaaaat tgtcactgaa atctatcgtg gtagcaaagt gaactttgag
     5281 aagaaagctc aaacacaaat tgctcaaatc gttcaaaacg gttgggacaa attgccaatt
     5341 tgtatggcta aaactcaata cagtttctca gacaatccaa atgcgcttgg agcaccagaa
     5401 aactttgaaa ttaccattcg tgaattggta ccaaaattag gtgcaggctt catcgttgcc
     5461 ttaactggtg atgttatgac catgccaggt cttccaaaac gtccagcagc tctcaacatg
     5521 gatgttgaaa gcgatggaac tgtactaggc ttgttctagt ggattgaaat tgactttaag
     5581 tgagtttgga aataatatcc aagctcattt tttctcagac tgcaagcagt tcatcaataa
     5641 gatttatact cttcgaaaat cttttcaaac tacgtcagct tcaccttgcc gtaggtaata
     5701 tgatactgac tctgtcagtt ctatccacaa cctcaaaaca gtgttttgag caacctgcgg
     5761 ctagcttcct agtttgctct ttgattttca ttgagtataa gtagatagaa aagttatata
     5821 ctatctattg aaaatattat aaatcagata caaagacagg tgaaaccttc tgtgttatac
     5881 tagagatatg ttagatttga aagaatacgg tatcgtcatg tggccggagg agaaagtcat
     5941 ttctttccgt gagaaacttc tcgcttggta tgatgaaaac aaaagagatt tgccttggag
     6001 gagaagtaaa aatccttatc acatctgggt atctgaaatc atgcttcagc agaccagggt
     6061 ggatacagtt atcccttact acgaaagatt tttggactgg tttccaactg tcgaaagtct
     6121 ggcaactgcg cctgaggaga gtttactgaa agcttgggag ggcttgggtt attattctcg
     6181 agttcgcaat atgcaggctg cagcccagca gattatgact gactttggtg gccaatttcc
     6241 aaatacctat gaaggaattt ccagcttgaa agggattgga ccttacacag caggagccat
     6301 ttccagtatt gcttttaact tgcctgagcc agctgtagat ggtaatgtca tgcgggtctt
     6361 ggcgcgtctg tttgaagtca accacgatat tgggattcca agtaatcgaa aaatttttca
     6421 ggcaatgatg gagatcttga ttaatccaga tcgtccgggt gattttaatc aagccttgat
     6481 ggacttaggg tctgatattg agtctcctgt aaatcccaga cctgaagaaa gcccagtcaa
     6541 ggactttagt gcggcatatc agaatggaac catggaccgt tatccaatta aatctcctaa
     6601 gaaaaagccg gttcctattt atcttaaagc cttagttgtg aaaaattctc aaggacaatt
     6661 tttacttgaa aaaaatgaaa gcgaaaagct cttggcaggt ttttggcatt tcccctttat
     6721 agaagttgat aacttttcgc aagaagagca gtttgacctc tttcatcagg ttgcggaaga
     6781 aagtgtgaac tctggcccca gtccagaaga gagtttccag caggactatg acctagatgt
     6841 tgattggctt gatgtttgtt ttgatacagt ccagcatgtt tttagtcatc gaaaatggca
     6901 tgtacagatt gtagcaggtc aggtgagtga cttccatgat ttttcagata gggaagttcg
     6961 ttggctttca ccagaagaat tcaagaatta cccacttgcc aaaccccaac aaaaaatctg
     7021 gcaggcttat gcacaagcca acttagacag tagccaagac tagctattgt gtcttctgac
     7081 tattttttgg tataatagta gagaaaaagg tgaacatatg aaaaaaatac taattgtaga
     7141 tgatgagaaa ccaatctcgg atattatcaa gtttaatatg accaaggaag gttacgaagt
     7201 tgtaactgct tttaatggtc gtgaagcgct agagcaattt gaagcagagc aaccagatat
     7261 tattattctg gatttgatgc ttccagaaat tgatggttta gaagttgcta agaccattcg
     7321 taagacaagc agtgtgccca ttcttatgct ttcagccaaa gatagtgaat ttgataaggt
     7381 tatcggtttg gaacttgggg cagatgacta tgtaacgaaa cccttctcca atcgtgagtt
     7441 gcaggcgcgt gttaaagctc ttctgcgtcg ttctcaacct atgccagtag atggtcagga
     7501 agcagatagt aaacctcaac ctatccaaat tggggattta gaaattgttc cagacgccta
     7561 cgtggctaaa aaatatggcg aagaactaga cttaacccat cgtgaatttg agcttttgta
     7621 tcatttagca tcgcatacag gtcaagtcat cacgcgcgaa cacttgcttg agactgtctg
     7681 gggttatgac tattttggtg atgtccgtac agttgatgtg actgtacgac gtctgcgtga
     7741 gaagattgaa gatacgccca gccgaccaga gtatatcttg acgcgccgtg gtgtagggta
     7801 ttacatgaga aataatgctt gatttactga aacaaaccat ttttaccaga gattttatct
     7861 ttatcctgat tttgttaggt ttcatccttg ttgtgaccct cttattactg gaaaatagac
     7921 gtgataatat tcagttgaag caaatcaatc aaaaggttaa agatttgatt gcaggagatt
     7981 attccaaggt tcttgatatg caaggtgggt ctgaaatcac caatattacc aataatttga
     8041 atgacttgtc ggaggttatt cgtctcactc aggaaaatct agaacaagag agtaagaggc
     8101 taaatagtat tctgttttat atgacagatg gggttcttgc gaccaaccgt cggggtcaga
     8161 ttatcatgat taacgataca gccaagaagc aactggggtt ggttaaggaa gatgttctga
     8221 atagaagcat tttggaattg ctcaagatag aagaaaacta tgaattgcgt gatttgatta
     8281 cccaaagtcc agaattgttg ctagattccc aagatatcaa tggtgaatat ttgaaccttc
     8341 gagttcgctt tgccttgata cgtcgagagt ctggctttat ttcaggtttg gtggctgttt
     8401 tgcatgatac gacggagcag gagaaggaag aacgcgaacg aagactcttt gtttccaatg
     8461 ttagccatga gttacggact cctctgacta gcgtaaaatc ctatcttgaa gccttggatg
     8521 agggggcttt gtgtgaaact gtagcaccag actttatcaa ggtttctctt gatgagacca
     8581 accgtatgat gcgcatggtg acggatctcc tccatctttc acgtattgat aatgctacca
     8641 gtcacctaga tgtggaactg attaacttca ctgcttttat tacctttatc ctcaatcgtt
     8701 ttgacaagat gaaaggacag gaaaaggaga aaaaatatga gttggtgaga gattatccca
     8761 tcaattctat ctggatggaa attgatacag ataagatgac gcaggttgtc gacaatattt
     8821 taaataatgc tattaagtat tcgccagatg ggggtaaaat cactgtcaga atgaagacaa
     8881 ctgaagacca gatgatttta tccatttctg accacggttt ggggattcct aagcaggatt
     8941 taccacgtat ctttgaccgt ttctatcgtg tggatcgtgc tagaagtcgt gcacaaggtg
     9001 gtacaggtct aggactgtct atcgctaaag aaattattaa acaacataag ggctttattt
     9061 gggccaagag tgaatacggc aagggttcaa cctttaccat tgtgctccct tatgataagg
     9121 atgcagtgaa agaagaagta tgggaggatg aagtagaaga ctagaatgag tgaaataggc
     9181 tttaaataca gtattttagc gtcgggttcc agtggaaatt ctttttatct ggaaacctca
     9241 aaaaagaagc ttttagtgga tgcaggcttg tctggcaaga aaattaccag tctgctagct
     9301 gaaattaacc gcaagccaga agacctggat gccatcttga ttacccatga gcattcagat
     9361 catatccatg gagtaggcgt tttggctcgc aagtatggta tggatcttta tgccaatgaa
     9421 aagacctggc aagctatgga aaatagtaaa tatcttggca aggtggattc ttcgcaaaag
     9481 catatttttg aaatgggtaa aaccaaaacc tttggagata tcgacatcga gagttttggt
     9541 gtaagccatg atgcagtcgc accgcagttc tatcgcttta tgaaggatga taagagtttt
     9601 gtccttttga cagatacagg ttatgtcagt gaccgtatgg cgggcattgt cgaaaatgcg
     9661 gatggctatc ttatcgaggc caaccatgat gtagagattt tgcgatcagg ttcttacgct
     9721 tggcgactca aacaacgaat cctatctgac cttggtcacc tttctaacga ggacggtgct
     9781 gaagctatga ttcggacgct aggaaatcgt actaagaaga tttaccttgg gcatttatct
     9841 aaggaaaaca atatcaagga actggctcat atgaccatgg tcaatcagct ggctcaagct
     9901 gatctgggag tcggagtaga ctttaaggtt tatgatacct caccagatac cgcaacacca
     9961 ttgacagaga tatagaaaga acgctgagaa ggtgttcttt ttatattgac tgaacaccta
    10021 aaaagtaata caatggtgtt accattaaaa aagggagcac aaaagatgac tactattaca
    10081 ttaaaagttt ctgaagctga taaaacattt atgaaagcaa tggctaagtt tgaaggagtt
    10141 tccctttcgg aacttattcg caccaaaact cttgaagccc tagaagatga atacgatgct
    10201 cgtgtggcag atttagccta tcaagagtat ttagaagact tggaaaaagg agttgaaccc
    10261 attacttggg aagaaatgat gcatgattta ggcttgaagg atgaataatt tgtataaatt
    10321 agttccaaca agacgtttca tcaagcaatt gaaaaaattg gaccgttata cgcagaagct
    10381 aattacaaac tatttacaaa tcaatgtttt ggaagaccca agacgacacg gaaaggcttt
    10441 ggttggtaat cgcgttggtc aatggcgcta tagaattggt aattatcgag ttatcgtaca
    10501 aattgtagat gatgaattag ttgttgctac tctagaagtt ggtcatcgga gagatattta
    10561 ttgaattaaa gctgagtaat aacaatatag aaagtaagga gagtaaaaat ttgaagaaaa
    10621 aatggttttt tgcagattat tatgatacaa caattatttt acttgcttta atctctgtta
    10681 ttctggtatt acttggattt gctgagatga ttgatttgga caatccgcct tatagtatta
    10741 ttgatttagt aatctggggt gtttttgtaa ttgattatag ttggcgcttt tttattacta
    10801 aaagaaaatg gcgctttatt cttgaaaata tttttgattt attggctatt ctccctttaa
    10861 atgctatttt cacagttttt cgattagggc gtatctttcg tttagttaaa ctaacaaaat
    10921 tactgaaact gactcgttta cttagaataa ttggacttac aggtaaatta gaaagaaaaa
    10981 ttagtagatt cttacggaca aatggcctga tttatatctt atatgttaat atctttatta
    11041 ttctagtagg aagttcaatt ttatctgtag ttgaagaaaa atccttctca gatagtcttt
    11101 ggtgggctct tgtgacagta actactgttg gttatggtga tattgttcca gtttcccttt
    11161 tggggaaatg gctagcagtt ttactgatgc ttgtcggtat tggaacaata gggatgctaa
    11221 caagtgcttt gacgaacttt tttgtaaagg ataatccaga tgaacagata aaacttgata
    11281 aactcaaaga cgaattatcg agctaaagaa tattaataga gaaacaatct gaaaaaatcg
    11341 aagaactaca ttgaatgata aaagacttag ttgaaaaaat atcataaagg tgagacaaaa
    11401 taaaacttga ttcgaggaga aatcaagtaa gtcttgacac aatagaacgc atattatcag
    11461 gtataaaaac ttgatactat gcgttttata gagaaataaa ataaaatctg aacaaatcaa
    11521 ttaggaattt aaagcatttt ataacaacgt tttagagtaa tggggtgcta tttcaacttc
    11581 aacctactat aatacagaaa aaaatacaga aaaaaacaac tccctgatga ttcaaggagt
    11641 tgtctatagt taaattagtt tttagaagct tcttggaatt ctggattttt ccatgcttcg
    11701 tcaataatag cttgcaattc tttagcagat gcttgcattt tttgagtttc tgcatcgttc
    11761 aatggaatgt ttactggacg aacgatacca tgtgcaccaa caacagctgg ttgaccgata
    11821 aagacattct caactccgta ttgaccttct tggaatactg aaagtggaag tactgcgttt
    11881 tcatcgtcaa ggattgcttt agtgatacga gcaagggcta ctgcgatacc gtagtatgtt
    11941 gcaccttttt tgttgatgat tgtgtaggct gcatcacgaa caccttcgaa caattcaatc
    12001 aattcagctt cttgaacatt ttgagtgtct ttaaggaatt cttcaaggtt tacaccagcg
    12061 atgttagcgt gtgaccaaac agcgaactca gagtcaccgt gttcacccat gatgtaggcg
    12121 tgcactgaac gagcatccac atccaatttt tcagcaagtg cttgacggaa acgagctgag
    12181 tcaagtgaag tacctgaacc gataacgcgt tctttaggga aaccagagaa tttccaagtt
    12241 gagtaagtca aaacgtcaac tgggttagca gcaacaagga agataccttt gaaaccagat
    12301 tcaacaactt gagttacgat tgatttgttg atagcaaggt ttttacctac aaggtcaaga
    12361 cgagtttcac ctggtttttg aggtgcacct gcagtgatca caacaaggtc agcgtctgca
    12421 cagtcagagt attgagctgc atagattttt ttaggtgaag tgaaggaaag ggcgtgacta
    12481 aggtcaagcg catcaccaac agctttttca tgcaattgtg gaatttcgat aattccaagc
    12541 tcttgtgcaa ttccttggtt aacaagtgca aaagcgtaag atgaacctac agcaccatca
    12601 ccgacaagga taactttttt gtgttgttta gttgaagtca ttgttttaaa catctcctta
    12661 attttattag gggattttcc ctagacaact tcattctatc acttttaaaa aactttgtca
    12721 cgaatatgcc ttatagttct ctatgtaaac gttttagtgg tttagaggct gaaatagatg
    12781 ggaatttatg gtataatgtt gttacttact aattgtgaaa tgaggcattt attaatgcag
    12841 gataaaaatt tagtgaatgt caatctgaca aaggagatga aggcaagttt tatcgactac
    12901 gccatgagtg ttatcgtagc gcgagctctt cctgatgttc gagatggctt aaaacctgtt
    12961 caccgtcgca ttctctacgg aatgaatgaa ttgggtgtga ccccagacaa accccataaa
    13021 aaatctgctc gtattacagg ggatgtcatg ggtaaatatc acccacacgg ggattcctct
    13081 atttatgaag ccatggtccg tatggctcaa tggtggagct accgttacat gcttgtagat
    13141 ggtcatggga attttggttc catggatgga gatagtgctg ccgctcaacg ttataccgag
    13201 gcacgtatga gcaagattgc tctggaaatg cttcgtgata tcaacaaaaa tacagttgat
    13261 ttcgttgata actatgatgc caatgaacgg gaacccttgg tcttgccagc gcgttttcca
    13321 aaccttttgg ttaatggagc aactggtatc gcggttggga tggcaaccaa tattccacct
    13381 cataatctgg gtgaaaccat tgatgcagtg aagttggtca tggataatcc tgaagtgact
    13441 accaaggact tgatggaagt cttgcctgga ccagattttc caactggtgc tcttgtcatg
    13501 gggaaatcag gtatccataa ggcttatgaa acaggtaaag gttcgattgt cctacgttct
    13561 cgtacagaga ttgaaacgac taagactggt cgtgagcgca tcgttgtaac agaatttcct
    13621 tacatggtca ataaaaccaa ggtgcatgag catattgttc gcttggttca ggaaaaacgc
    13681 attgagggta tcacagcagt acgtgatgag tcaaaccgtg aaggtgttcg atttgttatt
    13741 gaagtcaagc gcgacgcctc agccaatgtt attctcaata acctcttcaa aatgacccaa
    13801 atgcaaacca attttggttt caatatgctc gctatccaaa atggtatacc gaaaattttg
    13861 tctcttcgtc agattttgga tgcttatatc gagcaccaaa aagaagtggt tgttcgtcgt
    13921 acacgttttg ataaggaaaa agcggaagcg cgcgctcata tcttagaagg tctcttgatt
    13981 gcgctagacc atatcgacga agtgattcgt atcatccgtg ctagtgaaac ggatgcggaa
    14041 gctcaagctg agttgatgag caagtttaag ctttctgaac gtcaaactca agctatcctt
    14101 gatatgcgtc ttcgtcgttt gacaggtttg gaacgcgata agattcaatc tgagtatgat
    14161 gacctcttgg ctctgattgc ggatttagca gatattcttg ctaagcctga acgtgtttct
    14221 caaattatca aagacgaatt ggatgaagtt aaacgtaaat tttctgataa acgccgtaca
    14281 gagttgatgg ttggacaggt cttgagtctc gaggatgagg acttgattga agaatcggat
    14341 gtcttgatta ccctttctaa cagaggctac attaagcgtt tggatcagga cgagttcact
    14401 gctcaaaaac gtgggggtcg tggtgtccaa ggaacgggag tgaaagatga tgactttgtt
    14461 cgtgagttag tgtcaactag cacccatgat catctgctct tcttcacaaa caagggacgt
    14521 gtctatcgtc ttaaaggtta tgaaattcct gagtatggtc ggactgccaa agggctacca
    14581 gtagtcaatc tcttgaaatt ggatgaagac gaaagtattc agacggttat caatgttgag
    14641 tctgatcgca gtgatgatgc ttatctcttc tttacaaccc gtcacggtat tgtgaagaga
    14701 accagtgtta aggagtttgc caatattcgt caaaatggtc tcaaagcgct gaatttaaag
    14761 gatgaagatg agttaatcaa tgtcttgttg gcagaaggag atatggatat tatcattggt
    14821 accaagtttg gttatgcagt tcgctttaat caatcagccg ttcgtggtat gagccgtatc
    14881 gccactggtg tgaaaggtgt taaccttcgt gaaggagaca cagttgttgg tgccagcttg
    14941 attactgatc aagatgaggt tcttgttatc acagaaaaag gatatggtaa gcgtacagtc
    15001 gctactgaat acccaacaaa aggtcgtggt ggtaagggaa tgcagacagc taaaattacc
    15061 gaaaaaaatg gcttgctggc cggtcttatg actgttcaag gggatgagga tttgatgatt
    15121 atcactgata caggtgtcat gattcgaacc aatcttgcca atatttcaca aacaggacgt
    15181 gcaactatgg gagttaaagt aatgcgcctg gatcaagatg ctcagatagt gactttcaca
    15241 acggttgcgg tggcagaaaa agaagaagtt gggacagaaa acgaaacaga aggtgaagca
    15301 taatgtctca aaaaaaaaat aataaaaaga aaaacaagcg aaaaaatttg ctgacaaata
    15361 tcctagcagg atttctgata ttactgtcac tggctttgat ttttaatact caaattcgaa
    15421 atattttcat agtctggaat accaataagt atcaagttag ccaggtatca aaagaaaaat
    15481 tagaagaaaa tcaggataca gaaggcaatt ttgactttga ttctgtcaaa gctatctctt
    15541 cggaagctgt tctaacttct caatgggatg ctcaaaaatt accagttatt gggggaattg
    15601 caattcctga attggaaatg aatttgccga tttttaaagg acttgataat gttaatctct
    15661 tctacggagc tggtacaatg aaacgcgagc aagtaatggg agaaggaaat tatagtctag
    15721 ctagtcacca tatctttggt gttgataatg ctaataaaat gttattttct cctttagata
    15781 atgctaaaaa tggcatgaag atttatctaa ccgataaaaa taaagtttat acttatgaaa
    15841 tacgtgaagt caaacgtgtg acaccggatc gtgttgatga agttgatgat agagatgggg
    15901 tcaatgaaat cacattagta acctgtgaag accttgctgc tacagaacgt attattgtca
    15961 aaggtgattt gaaagaaaca aaagattatt cacaaacatc taatgaaatc ctaacagctt
    16021 tcaatcaacc atataaacaa ttttattaat acaaatcagt gaaatcatgg atttcactga
    16081 ttttttaaga ttttcata
//
LOCUS       DAVKMO010000045        15631 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVKMO010000045 DAVKMO010000000
VERSION     DAVKMO010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15631
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.045"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            104..268
                     /locus_tag="VW361_001595"
     CDS             104..268
                     /locus_tag="VW361_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9744605.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPAIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            352..918
                     /gene="amaP"
                     /locus_tag="VW361_001596"
     CDS             352..918
                     /gene="amaP"
                     /locus_tag="VW361_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU9744606.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            930..1100
                     /locus_tag="VW361_001597"
     CDS             930..1100
                     /locus_tag="VW361_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU9744607.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1139..1747
                     /locus_tag="VW361_001598"
     CDS             1139..1747
                     /locus_tag="VW361_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9744608.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1778..1981
                     /locus_tag="VW361_001599"
     CDS             1778..1981
                     /locus_tag="VW361_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9744609.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2091..2363)
                     /locus_tag="VW361_001600"
                     /pseudo
     CDS             complement(2091..2363)
                     /locus_tag="VW361_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(3132..3902)
                     /locus_tag="VW361_001601"
     CDS             complement(3132..3902)
                     /locus_tag="VW361_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU9744610.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSNIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3917..4765)
                     /locus_tag="VW361_001602"
     CDS             complement(3917..4765)
                     /locus_tag="VW361_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEU9744611.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4762..6237)
                     /locus_tag="VW361_001603"
     CDS             complement(4762..6237)
                     /locus_tag="VW361_001603"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEU9744612.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLERQIPSIYALRGKLKEDDQRRMVAAYLGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6560..7915)
                     /locus_tag="VW361_001604"
     CDS             complement(6560..7915)
                     /locus_tag="VW361_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9744613.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7925..8242)
                     /locus_tag="VW361_001605"
     CDS             complement(7925..8242)
                     /locus_tag="VW361_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9744614.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8259..8576)
                     /locus_tag="VW361_001606"
     CDS             complement(8259..8576)
                     /locus_tag="VW361_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9744615.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8591..9487)
                     /locus_tag="VW361_001607"
     CDS             complement(8591..9487)
                     /locus_tag="VW361_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU9744616.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9490..10752)
                     /locus_tag="VW361_001608"
     CDS             complement(9490..10752)
                     /locus_tag="VW361_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9744617.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            11032..12210
                     /locus_tag="VW361_001609"
     CDS             11032..12210
                     /locus_tag="VW361_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU9744618.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLISQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEKCSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(12438..12884)
                     /locus_tag="VW361_001610"
     CDS             complement(12438..12884)
                     /locus_tag="VW361_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744619.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQTLRKFVSLAFE
                     NEDIDNISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            12954..13613
                     /locus_tag="VW361_001611"
     CDS             12954..13613
                     /locus_tag="VW361_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU9744620.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(13665..14816)
                     /locus_tag="VW361_001612"
     CDS             complement(13665..14816)
                     /locus_tag="VW361_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU9744621.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDNYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(14831..15562)
                     /locus_tag="VW361_001613"
     CDS             complement(14831..15562)
                     /locus_tag="VW361_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744622.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHASYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
BASE COUNT         5211 a         3124 c         2378 g         4918 t
ORIGIN      
        1 tttgatatta aaataaaaaa ggagggtagg cagtgttgtg atcaattatt gctggaggtc
       61 ttattggtct cttggcaggt aaaatcacta aaaaagtagt tctatgggaa tcatcgcaaa
      121 tgtattcgct ggtttagtcg gggcatatgc aggacaatct cttttaggta gttggggtcc
      181 agcaatcgct ggaatggctt tgctcccatc tattgtaggt gcagcgattg tgattactgt
      241 agtgtcattc tttacaggta gaaagtaaac ttttcgccag taaagttagc aaactatttt
      301 taaatcaatg acgggaaaaa tagtttaaat gttaaatcga aaggattgta tatgtcaaaa
      361 gcaaagaaaa tatgtttcat tattttctgt attttaatct tgacaatttt ccttcctgtt
      421 ttgatagatt atcatcaagt tagtgatcta ggtattcatc tacttagctg gagacagaac
      481 tccgtagttg aattctatct tgctagatat gtcttttggg ggacagtggt tctatcaact
      541 ttagttttat tatccatttt agttgtgatg ttttatccta aacgttactt ggaaatccaa
      601 cttgaaacta aaaacgatac attaaaatta aagaattcgg caatcgaagg ttttgttaga
      661 agtttggtga gtgatcatag attgatcaag aacccaactg ttcatgtaaa tttacgaaaa
      721 aataaatgtt tcgttcatgt agaaggtaaa attcttcctt cagacaacat cgctgacaga
      781 tgccaaataa ttcaaaatga aataactaat ggattgaagc agttttttgg tattgagcgt
      841 caagtaaaac ttgaagttgc agtaaaaaat taccaaccaa aacctcaaaa caaaaagact
      901 gttagtcgtg tgaagtaagg aagtaaaaaa tggaatggct taaacaatat cgatatccaa
      961 ttatcgctgg tctcataggc gtatttctgg cttgtttgat tgtctccttt ggcttcttca
     1021 aaacaatatt tgtattgatt ttaggagcac tgggagttgc agctggatta tatatcgaaa
     1081 aaaactatat agataaataa aaaaataaaa attactaatt taattaaagg agtttcatat
     1141 gtcaaacgaa aaaaacacaa acactaacgt agaaaagaaa gatgctactg ttgtagctca
     1201 cgaaatcaaa ggggaactta cttacgaaga taaagttatc caaaaaatca ttggtctttc
     1261 actagaaaac gtttcaggtc ttttgggaat cgatggtggt ttcttctcaa atcttaaaga
     1321 aaaaatcgtt aacagcgatg acgtaacaag tggtgttaac gtagaagttg gtaaaacaca
     1381 agttgcagtt gacttaaacg ttattgttga gtaccaaaaa aatgttccag ctttatattc
     1441 agaaatcaga gaaatcgtat cttcagaagt tgctaaaatg actgacttgg aaattgttga
     1501 aatcaacgta aacgttgtcg acatcaaaac taaagaacag catgaagcag actcagtaag
     1561 ccttcaagat cgcgtatctg acgttgctga atcaacagga gaattcactt cagaacaatt
     1621 cgaaaaagct aaatctggtc ttggatctgg tttctcaact gttcaagaaa aagttagcga
     1681 aggtgtagaa gctgttaaag gtgcagcaaa tggtgtagta tctcacgaaa acactcgtgt
     1741 aaactaagat aaaataaata taacaggaga aattatcatg tcagtagaag aaaaattaaa
     1801 tcaagctaaa ggttctatta aagaaggtgt tggaaaagcc atcggtgatg aaaaaatgga
     1861 aaaagaagga gcggctgaaa aagttgtttc taaagttaaa gaagttgccg aagacgctaa
     1921 agacgctgta gaaggtgctg tagaaggtgt taaaaacatg ttgagtggcg acgataaata
     1981 aggttaaaag ttactttatc tttttggtaa cattagtcaa aagagtctga gtcgagatga
     2041 ttctcagaaa acaaaaagct agagattccc aattgcggaa ctctagcttt ttaattttgc
     2101 ctctttctct tattatattt cagcaggttg ttggccatga gtatgaatcc catgtcaatt
     2161 ctcacttgac gcttccctct cagatgacat ctcttataac ccaaacaaac ctttatctgc
     2221 ccaaagacag atttcatatc aatcttacgt ttagcgaaaa tttgtctacc cttggaagat
     2281 aaaagtgcct gatattcttt agtttttaaa cactggtaac gttcattcat atacagtctc
     2341 ttttgagggg ctgattcagg ttcataatcg cagtcaacat tgatttcaag gctgtttgct
     2401 ttctatctcc cctttttcat gatatatttt cgtacaggtg cttcaatagt ttctatagta
     2461 aaatgaacca aaaatagtac acgttgcggt ataatgttct tatggcatat tcattagatt
     2521 ttcgtaaaaa gttctctcct atttgtgagc gaacaggtat agtcaattga ttgtcagttt
     2581 gaagaccaag agtcgtaagg caaaggatat ggcagaatcc atccaagggt ggctggcaca
     2641 atttctagtg aacctcttta aatctattac gtttgactgt ggaaaagagt tttcaaaatg
     2701 gaaagatatt tccaatcatc acgacagtga gagctttttt gcgaatctag gatgtccaag
     2761 acagcggtgt ctcaacgaac attcaaatag acttttaagg tgtcatgact tgccaaagta
     2821 gacagatttc aacgaagtca gtcaagaatt ttaggctgga caaaaactca atttcaggag
     2881 aaaatgaaat aaatattccc acaataaaac gcatagtatc aaagtttttc caatacctga
     2941 tattatgcat tttttaattt taaagacttt ttcccagcct caagaaatca catcccacct
     3001 aaatcctttg gataccaaat acctcatcag gtattttctg agttggtaag actgtctagc
     3061 ttaatttgac aaatggaggg cgttaaatcc agtttttaca ggaagtctat ttaaatattt
     3121 tcacactgac cttacaaaat atgaaataaa ttatataaag tcattcccat gacaaagaat
     3181 aacatccctt taaaacagta tcttacccaa ttttcaggta agacttttga tacaaccgtc
     3241 cccaataccc ctccgcatat agaagcaaga aaaataactg gaacaggtgc taaatgatac
     3301 tgatttaaac ctgtaaccac aacaattgta gccaaatgag ataactggga aaagaaaata
     3361 attgcaagag aatacatcgt tgcttctttt atcgaaatag aaaaaaacac catcaataaa
     3421 gatacattga gcggaccacc accaatccct aaaaaactag aaattaagcc caatagaaga
     3481 ccacaaatca tatagaatcc tatcttatca aattgataag tttttttaaa atctgttaaa
     3541 acaaatgata caagtagcat cacaaatagt aaaatcattt gaacaatgga tactagccgt
     3601 actgataact gagataacaa aacttgaaaa ataagatgac ctagaaatcc tcctaaaaca
     3661 gaagaaaagg ataccgtaaa aatcaatctc cattttatct ctttactttg tgaaaatctt
     3721 ttgattgttg aaataatcgc cattataaaa acagagaaac tagaataaaa agcaatatta
     3781 ctgaccgaat ggtatccaaa actatccata agtggcttaa ttataattcc accacccatg
     3841 cctgatatag aacccaatcc actagctatt ataatgatta gaaaataaat aatctcaacc
     3901 actttttaag tccatcctat tctttcaaac atctaaaacc tagatggcta ctagtggaag
     3961 tagaaataca tccatttcta gcagctactc ggtatcgatt acaataagaa caatgacata
     4021 aaaaggaacc tcctctgata gcatactcct catcttgtat cccatatttt ggtaactcat
     4081 agtcatcttc attaaaacta gctaataagg tatatctcgg attgcgacac cattcccaaa
     4141 cattcccaat catttgatat agaccaaaat cattaggtaa aaattcatag acaggagccg
     4201 ttcctataaa tccatctaag gcagtatttt cataaggaaa tcttccttgc caagtattgg
     4261 catgataata tccaccttct aaaagagtat ctccccaagg atattcagat tgtcttcctc
     4321 ctctagcagc atattcccac tgtgcttcag tcggtaaaga cattccgctc caattacaga
     4381 aagccaatgc atcttctaaa gcaacatgaa ctactggatg gtcttctaaa cccactagat
     4441 tactattctc accgtaggga tgtttccagc aagcgttcgg aacttgtaac caccacggag
     4501 ccccagcagg atgaggatat ccctcccttt ctgcctctgg aacgaacaat ataaaaacaa
     4561 aagaccactc ttgtcgctca gctagtgttt tatagcctgt ttctttcaca aattgagcaa
     4621 attcttgatt cgtaactgga gtatccgcaa tggaaaaatc ctttacacta acagcgactt
     4681 gaggaccttc aaaatcatct aaaaagccct cttcagaatt tgttcccatc ataaatgtcc
     4741 cacccttgat ttttttcatt ttcatgattg actatccccc gttttcgtta gagttggcgt
     4801 tattttagaa agttcaacag gaactaactc ttcatccaca acaaaacctt cttctctata
     4861 tctaagaaag tctactaatt ttttcttcat ctgacgaaca ataggttgat atttttcact
     4921 tggatacaaa tcattcattt catgcggatc ttttttcata tcaaataact gataatgatt
     4981 taaaacagga aaccagataa atttccactg gtctgtcaag atatattgac tagaatcttt
     5041 tcctaaagca tgttcaccat gaaattctgt tcgccacccc tcgtactgtc caaataataa
     5101 attcttaaca ctccgtccat ctagttcatc tgtagtagtt cctcctgcca aatccacgag
     5161 tgaaggaaaa atatcttgaa ttttcactaa ttgcttgatt gttcccctat taccagctat
     5221 caatccagcc ggatcgtaaa tgaacgaagg aatgtggata cttccttgat aaggatatcc
     5281 ctttctaaac agataatgtt caccaagctg atctccatga tccgaaacaa accagataat
     5341 cgtatcttta tcatgacgaa attcttttag ggcagtcaaa aagcgactaa tttgatggtc
     5401 tatatgagta atcaatccca aataagcagc aaccattctt ctttgatcat cttcctttaa
     5461 tttccctctt aaagcataaa tagacggaat ttgcctttct aatacttccc aattcccgat
     5521 atgcaaatcg agaaattgag gcaagcgttc catatacata tcaaaatagt attttggggg
     5581 atttaatgga gcatgtggtt tttcaaaaga cattttgaga aaaaaaggaa ccgttggatc
     5641 tcttctttgt aaaaatgaaa tggactcact cacaacccag tttgttggat gtaacttctc
     5701 atctttatcc caaggtctag cttcccaaga attacaatcc attccgtcat caatcaaatc
     5761 aacatcataa ccaactttac cctttaaaaa ggctagatag tcactagcat aatcaaattg
     5821 acttccataa gccttatcat actttctatc aacatgtaga tacccatcgt gaagtaagac
     5881 atgatcaaac ccaagtctct gtctggaagg aaaaacatgc atcttaccaa tacactctgt
     5941 ttgataaccc atatctttaa agacttttgg aagagtatta gtaaaattcc aaggcacctc
     6001 atcttgataa ccaacacgtc cacttttatc ttggtctaaa ccagtcaata aagctgccct
     6061 agcaggaacg caagaaggaa ctggagaata ggcattttca aaattataac ctacactagc
     6121 catcatatct aatgttggag tgctaactag cttatcctta ctattcaagg ataaggcgtc
     6181 tgctctcatt tgatctacaa caatcaaaat aatatttggc tgttttgtct gaaccataaa
     6241 atctcctttc taatatggca aaagaggcac aagaagatat ctacctttac tgcacccctt
     6301 tctatatcaa tctctctata taaaacaata acattcttgt tatgttttat ataaaaatga
     6361 actaaaatat gactaaatcg attaggaaat tcaaatcatt ttctagtact gttttagaag
     6421 ttacagtgta ctattccaac ttcaataaac tataaacctt tgtctattaa caattttagt
     6481 ggagataaga aatcctacac ctaactcatc ttacacgtaa tctatttcta ttttatcaca
     6541 aaaaacgcaa gtaagaccat taactcaatt cagttttatc tgccattttc acaaatggga
     6601 aataagtcaa gacactaata atcaaacaaa caactgataa gatgatggca cgccaatcaa
     6661 atgctgtaga gaagaaacca tataaaattg gaggcattac ccaagtaaca ttttgtgtaa
     6721 caggtgaaac aagaccccag cttgttgccc agtaagctac cgttgccatg aaaaccgggc
     6781 taagtacaaa tggtataaat agcaaaggat tcaagacaac tggtaaacca taattgaccg
     6841 gctcaccaat attaaacaga actggtgcta gaccaagttt agcaactttt cgataatgac
     6901 tgtttcttga aaaaattaaa atagcaagta ctaatcctaa tcctccaaac cagacaaacg
     6961 ccccaaaaga cccacttgtc catatataag gaatcggttc acctttttgg aaagcatcca
     7021 gattcgctaa catagcaact ccaaatagcc cttccatgat gggagccaat acatttcctc
     7081 catggagacc aaaaaaccag aataacttat tcaaaaagat catcagaata actgcaaaga
     7141 aactttgaga caaacctagt aatggcgttt gtaacacctt gtaaacccaa tcaatcaata
     7201 agtcattgct aagtaaatgg aaaacataag tcaagatggc tactatatac atcgccataa
     7261 atcctggaat gatagaagtg aacggcttag caatcgcagg gggaactgaa tctggtaact
     7321 tgattaccca gttctttttc attactttac agaaaataat agaggctaaa aatccaatca
     7381 tcatggctgt aaagtatcct ctggcattaa tatggtttcc tggaatcaca ttcccaatag
     7441 ttaccatcag atttttacca tcaaatgcta gattatcaat tccttgtaag atttgatcta
     7501 atttcacatc tcctacattt gccaaaggga aactctttgt aactgtactt ccaatcgaaa
     7561 tgacaaacga agcaagtgat accaaaccag cagaaactgt atcaaccttg taaatcttag
     7621 cgatattcac tcccaagcaa tagatgaaca acaaggaaac aattggtata cttcccttga
     7681 ataccaaatt attgatgtca acaagccact gaaaggtttt cgtaatactt tctaggtgaa
     7741 attgttgtgg taaatccact agaaaagcat ttaataacaa agcaatggaa cctgtcataa
     7801 taacaggcat agtccccaca aatgaatcac gtaaagcaac taaaaacttc tgattcccaa
     7861 ctttcattgc aattggagag agtttttctt gcattttatc caacattgta ttcatactaa
     7921 actcctaatt tttttcaaat cgttcgtata cttctaccac ttctttcgcc aagtcaacaa
     7981 aagtcagact cgtcattaaa tgatcttgcg cgtgtaccat caagaggcta attgatgttt
     8041 cttccccctg tgcctctctt gtcaacattt ctgtttgagc cttatgcgcc tgtaataagg
     8101 cagcattcgc atcagctaat cttcgattgg ctttagagaa atcccctttt tttgctgcct
     8161 gaatagcctc catagcatta cttttggctt ccccaccata cataattagc cccattgcag
     8221 attctaaatt actttcattc atagcattct cctcaatctt agtctaataa actttcagct
     8281 aaatctaaga ctttagaacc attcatcatt ccataatctg tcatcggaat aaccgccaca
     8341 ggaatctgtc tatcttttag tttttcttga aagtccccta gtaaatagcg aacttgaggg
     8401 cctaaaagca acacatttac ttcctttgtt gctacaattt cttctgcttc aggagctgga
     8461 actgcaaaaa tttctgcatc caacccctta tcttctgctg ccttttgcat ctttgtcact
     8521 agcagacttg tactcatacc tgctgcacat gctaacataa ttgttacttt agccatagct
     8581 tactccttta tcacctattt actgacctag ccaagcgaga tactgtatgt ctcactcctc
     8641 taattgcctt gctcaatgca taaatattat cgactgttgc cagtccccca tatcctgcgt
     8701 cacctatatg ttgaatatca actccacaaa ttttatttct aagtgcaatt tccttaatag
     8761 tatctgtatc agatgtttct tggctagtac caatagcact caatacaaga ccacccttac
     8821 tatgaacgag atcaacgact tcacgcaact cttggtcatg aaaggctgga acggttccaa
     8881 ctgctggaac aagtatcaca tccgcacctg cttccaacaa ttgctctgcg acagaaagct
     8941 ctgccacagg ctcattcact cctgccccgt gcatcttacc tgcaataatc aaaccagaaa
     9001 agttttcctt agcagtttga acagccttaa tgatttctcg attgctaact cctgttccag
     9061 gatttccagt caaacagaca aagtcaaaac ctaactcctc tattcgcttc aatgtttcaa
     9121 cactagcaac acgacctgca acaatttcct gtgtttcctc tagcatcttt gcagatgggt
     9181 caatcggttc caaatttaca ccaattggac aagcaacaag ctggtgtaag cgatgaataa
     9241 catcatcacc tgaactatcc aaagcataaa ttttaggctc aaaaacatca acacaattca
     9301 ataaaatcat atcagctcca aaagctctag caatttcaga attagttata tccccaacaa
     9361 atgtctcacg agtaactaca ttttcagata gaacaactct accttcactt gctaaaatac
     9421 tttgttttaa ttcttcagca ttcatctgta atatctcaga tggatttgca ctaattaaac
     9481 gtttcattct caatcctcca ataacttaaa ccgtttttca atagctatta caaatggtaa
     9541 ataaagtaag acatccaaaa caatcaatac aatttgtaat aatgaaccag aaatacttcc
     9601 tgtagcaagt aaaccactta taacaggtgg catagtccaa cctggatctg tataagttag
     9661 cggaaccaaa cctgatgcca ttgctcccca cgctactagt aagttaaaca ttggagctaa
     9721 gataaatgga actagtaaca aaatgttcaa aacaatagga acgccaaaca ttgctggttc
     9781 atttatatta aataatccag gtataacagt tataggtgcc aaagttttta gttgtttact
     9841 agctttcttc ttatgtgcta aatatcctaa cgcaagaact aaacctatgg ttgcaccacc
     9901 gccacctatg aatacaaaat tatccataaa tacgctagta aaaatatttg gaagagtttc
     9961 tccagtttga taagctactt tatttgcatc tagattagct aaccataacg gtttcataac
    10021 tgcattaaca acatttcctc cgtgtaatcc tacaaaccaa aaactactat taaggaaaat
    10081 taagataaga agaccaataa cattatttcc taaaagtcca agtggacctc ccaaagctac
    10141 ttgagcaatt tcatgaagat taggtaaact taatttatct aaagttgcat aaacaatcaa
    10201 ccaaccaaca atagtcactg caccaggaat aatggcacta aagcttttag atactgctgg
    10261 tggaacacca tccggcattt ttatctgtat attatgattt ataaaccatt ggtagatata
    10321 gccattaatc aatcctaaaa tcatagcaac aaataaacct tttgatgcca tgaaagcggt
    10381 aggcattcct gctccagcct ctcctgtaat gaaaggcgta actgtaataa aagatgataa
    10441 tgacacaata ccagcaggaa taccatcaac tttgtattgt ctagccataa agtaagcgat
    10501 accaaaacta gctacaagac caagtaatcc aaaactacta tcaacaccct tccataaata
    10561 gtcagcaaca ccaatatcac ccagatattt ttcccatcct ggaataggaa aacttgcaat
    10621 aaccattagt aatgaaccta tcaacaataa aggtatagtt agagtaatac cgtctcgaat
    10681 agaaaccaac gctttattat tacccaatct agccgctact ggaagtaact tttcttgtaa
    10741 taatttttcc ataacctttt cctcttaaat atattttatt atcaaaagtt atcaattatc
    10801 tttatttttt gacgtcaagt tgttatttga ttatcttttg ttatttatat tttacaacta
    10861 taagaaagcc ttgtcaagga tttgtgtaaa tatttgatta ttttttatta tcaatatata
    10921 ataaaaagag accagtaagc aatgaaaagc ttaaaaagat taacatctac atttatccat
    10981 agtaaaaaat cataggattt taagaatctg acaactagga agaaaactaa tatgacctta
    11041 tctaagaaac aattacaact acgagctaaa atactggaaa cagtttacac attaggtccc
    11101 atttcacgaa ttgaaatcgc tactaaaaca ggaataacac ctgcaacaac tagcagtatc
    11161 acaaatgatc tgattaaaga aaacattctc ttagaacttg gtgaagacga acacgataca
    11221 agcgtcggga gaaaaaaaat cctgctagac attcaagcta aacgatttta ctacattggt
    11281 tgtgaactat ctgaaaaaca tttcactttt gctttaggag ataatctagg aaatatctta
    11341 aaggaagaga aagaaattgt tactaaacag ttaatccaag aaaagggaaa tcaactcatt
    11401 agccagacac taaagcaatt cttaaataac tgctctgatt atgaaataga agcaattgga
    11461 atcgcgctac ctggtcgcta tttagatgat tataaaataa caacaaacaa tcctttatgg
    11521 caacatatcg acttagaaat gattcaatcc cactttgata agcctttgtt tttctctaac
    11581 aatgttaact gtatggctat aggtaaacgc ctatttagtc gccaacagaa tgaccctaat
    11641 tttgcttatt ttcattttgc tagaggtatg cactgttctt atatctacga cggaaacatt
    11701 tatgggaaag gaaatctaat gattggagaa atagggcata cagttgtttc atctgaggga
    11761 gaaaaatgta gctgcgggcg caagggatgc ttacaaactt ttgctggaga atcttggtta
    11821 atcaaaaaat caaaaattct atatcatcaa tctccctatt ctctacttcc tagtttagtc
    11881 aaaaatgccg atgatattga tatccaagtt attttaaccg cttatcaatt aggtgacact
    11941 ggaataatca cacttatcca tcaagcctta ctctatctta gtcaaaccat tttaaatatc
    12001 agtatgatga ttgactctca aaaaatctac ctacatagtc ctttactaac aaatcaacac
    12061 atcatccaaa aactatatag tgaaatgaac tacaaaccca aactgctcta taatcgccta
    12121 cctgaagtca ttattgaacc ttacaatgat tttacagccg cacactcagc tattgcactt
    12181 tgtttgtatc atacaattct acattcctaa ttttctatta catttaataa ataggctaaa
    12241 aagagggagt atatcataaa aagcgaacaa acctgttttc tgaaaatcag aattctgttt
    12301 tgttcgcttt ctttatattt ggaattatac tcctatctcc catttttcat aatgtatagt
    12361 aaaatgaaat aataacagga cgaatcgatc gggacagtca aatcgatttc taacaatgtt
    12421 ttagaagtag aggtgtacta ttctagtttc aatccactat attttcgtac aggtgcttca
    12481 accatttgaa cgatttcaaa tccttctttt tggtaaagat tctgagctct ttgatttgcc
    12541 tcgaagacat ttagagaaat attatctata tcttcatttt caaaggccaa actaacaaat
    12601 ttccttaaag tctggctacc taagccttgc ccctgtttct gggggttgat aaaaaatctc
    12661 ccgatatgaa gattgctgtc ttctagcctg attttctgga taaggcccac aaactcttgt
    12721 tcatcaaaga ttgaaaatac ttcttccaag gcttgaaggg tcagtagaaa aggaatcctt
    12781 ggtcccatcc attgttcttg aaaggatttg cctagggagt tggaccattg gcatacaaat
    12841 tgagcgtttt ctatactcac cttttcttca aaacgaattg tcatcttttc ctcaccatct
    12901 tatctatgtt tctccattat actatttctc ccatttttta cgaatagata agtatgattg
    12961 atttttattt ttttctcgtc gggagcattc tcgcttcctt tcttggtttg gtcattgacc
    13021 gttttccaga gcaatccatt atcagttcag ccagtcactg cgattcctgt cagactcgct
    13081 tgcgtccctt agatttgatt ccgattctct cacaggtctt caatcgcttt cgctgtcgct
    13141 actgcaaagt tcgctatcct gtctggtatg ccctctttga actaggctta ggactcctct
    13201 ttctgcttta ctcttgggaa ttgctttcct tggggcaagt cgtcctaatc accgctggtt
    13261 tgaccttggg tatctacgac tttcaccatc aggaatatcc cttactggtc tggatgactt
    13321 tccacctaat cctaatagct tcctctggct ggaatctggt catggtctcc ttccttgctc
    13381 ttggaatttt ggctcatttt atcgatatcc gcatgggcgc aggagatttc ctctttttag
    13441 cttcttgtgc tctcgtcttt agcgtaacgg agttactgat cttgattcag tttgcttctg
    13501 cgacgggtat cctggccttt ctcctgcaaa agaaaaagga aagacttcct ttcgtgcctt
    13561 tcctcttact tgctacttgt ttgattattt ttggtaagct actgcttgtc tgataaaatc
    13621 caatttctgc catatatcct tcatgaaatt atttcacagt taaattataa attatttctt
    13681 ttgtacaaag ggatgatgtt atcaaatcga tctgttcttc tatcttcttg atactgatca
    13741 aaaaatttca tttcgactga aaatatttcg cttataaact gtaaacgaat actttgttta
    13801 gacattatag tcgctagact gactagatga ttactcaaaa cgacgtccag aatactcttt
    13861 actttgcttg gttttttaac aaaaatttga tcatccaaag gttcaatcat tttgtaacct
    13921 ttttgcgcaa tttgacgata aaagtaagaa tgttgctttg gagtcaataa tcctaactta
    13981 aaagctcgat actctaaagc ctgtatcgaa acattcaaat ccgacttcaa taaaatataa
    14041 ttatcaggat tgctgacacg cttgccaacc ctctcttcaa atttgactaa aaactcttct
    14101 tttggcaata aaaaacatga tgcaaaataa tttgcttctt gctccaaacg atcgccatct
    14161 tcattcatat ctttatattt atgtaaaaga atatgtccta gctcatgagc taagtcaaaa
    14221 tttcgacgta cagatgattt attcgttccc aacacaatat aaggtcttcc caattttgac
    14281 catgcgctat aagcatcagc ttggccatta attaatcgtt ccacgatata gatgcctgaa
    14341 cgttctaatt tataaagcaa atcatgatta tcttttgaaa tacctaattt ttccctggca
    14401 taaagagcca attcctcaat ggattctccc ttatgataag attcactcac tacattactt
    14461 aggtcatgaa ttgtaatatt aggtataatt acaaaacttt caaaataatc aatcaaacta
    14521 tctaccttat gtaaatacat agtttgaata tctattgttt tccgtgttgc taggtctgca
    14581 tttctaaagg caattacaga agaatcaaat cgaatgctct cttcttcctg ttcaaaataa
    14641 gttaaatcaa catgaaattg gttggccaaa tgcattttgg ttgataattt aggtttcgtt
    14701 tcgttggact caaactgcca aatggcttgt tccgttaaat taattctctg agctaattct
    14761 gctctactta aaccatttaa cagccgtaat tctttcaata cccgaccatt aaacatttac
    14821 atactcctta ctacttttga ccttcttgtt tttctattct tggaataatt tcaaaatctt
    14881 ctgtttccga taattctgaa aaattaggaa tatcttgata tttagcttct tcgaaatggt
    14941 acgaacttga ttgaatatac tcagacaaat cttgaatcaa gtgtaactga ccagttcgtg
    15001 catcaggcat aacaacatct acagatataa tattgttttc tgagtccgcc tcataagtta
    15061 aaatcataaa tttttcgata ttcgaatttt tagtagcttg ttcaatttct tgaatcattt
    15121 catcagaaac taactccatc tgaattggaa aggaatgact atcttcatca tttttgtagg
    15181 aagcatgttg attaagataa agtgtattca tctgagcata ttcaaataag tagccactct
    15241 tatttttttg taccaaagga aattggttcg taagtcgctt cttacccttt ataattaaca
    15301 atactttccc atatttttct gtatttgttt caaattctaa atatccccaa gtctgtcctg
    15361 ctaattgtaa tttatactca aacaaatctg ctgatgcaaa tgcagtatca atatgattag
    15421 gtcgcgtcca tgcataacca ttcgacacta tcattgtctc tcttttttct agacgttcat
    15481 ctacataatc tttttgccct ttcatcaaag tatctacaat tttttgtgcc tcaagcgaat
    15541 caaagagatc ctgattcaac ataattcttc ctcctccaaa tactttttaa tgaattatat
    15601 cattttctta aagaaattac tacaataatt a
//
LOCUS       DAVKMO010000046        15057 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVKMO010000046 DAVKMO010000000
VERSION     DAVKMO010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15057
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.046"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..154)
                     /locus_tag="VW361_001614"
     CDS             complement(<1..154)
                     /locus_tag="VW361_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9744623.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELL"
     gene            complement(167..940)
                     /locus_tag="VW361_001615"
     CDS             complement(167..940)
                     /locus_tag="VW361_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9744624.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKDLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(1386..2141)
                     /locus_tag="VW361_001616"
                     /pseudo
     CDS             complement(1386..2141)
                     /locus_tag="VW361_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(2279..3901)
                     /gene="groL"
                     /locus_tag="VW361_001617"
     CDS             complement(2279..3901)
                     /gene="groL"
                     /locus_tag="VW361_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU9744625.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(3917..4201)
                     /gene="groES"
                     /locus_tag="VW361_001618"
     CDS             complement(3917..4201)
                     /gene="groES"
                     /locus_tag="VW361_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU9744626.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(4471..4866)
                     /locus_tag="VW361_001619"
     CDS             complement(4471..4866)
                     /locus_tag="VW361_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU9744627.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(4943..5704)
                     /locus_tag="VW361_001620"
     CDS             complement(4943..5704)
                     /locus_tag="VW361_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU9744628.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALGLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMVKVNQGHVINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(5737..6363)
                     /locus_tag="VW361_001621"
     CDS             complement(5737..6363)
                     /locus_tag="VW361_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU9744629.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(6379..6696)
                     /locus_tag="VW361_001622"
     CDS             complement(6379..6696)
                     /locus_tag="VW361_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU9744630.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(6693..6992)
                     /locus_tag="VW361_001623"
     CDS             complement(6693..6992)
                     /locus_tag="VW361_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU9744631.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGAIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(7277..7468)
                     /locus_tag="VW361_001624"
     CDS             complement(7277..7468)
                     /locus_tag="VW361_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HEU9744632.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(7629..8303)
                     /locus_tag="VW361_001625"
     CDS             complement(7629..8303)
                     /locus_tag="VW361_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744633.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(8309..8755)
                     /locus_tag="VW361_001626"
     CDS             complement(8309..8755)
                     /locus_tag="VW361_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9744634.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRIKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(8869..9372)
                     /locus_tag="VW361_001627"
     CDS             complement(8869..9372)
                     /locus_tag="VW361_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9744635.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(9369..9731)
                     /locus_tag="VW361_001628"
     CDS             complement(9369..9731)
                     /locus_tag="VW361_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEU9744636.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDSLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10040..10756)
                     /locus_tag="VW361_001629"
     CDS             complement(10040..10756)
                     /locus_tag="VW361_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9744637.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(11637..13052)
                     /gene="ply"
                     /locus_tag="VW361_001630"
     CDS             complement(11637..13052)
                     /gene="ply"
                     /locus_tag="VW361_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU9744638.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWNELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(13063..13395)
                     /locus_tag="VW361_001631"
     CDS             complement(13063..13395)
                     /locus_tag="VW361_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744639.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(13466..14074)
                     /locus_tag="VW361_001632"
     CDS             complement(13466..14074)
                     /locus_tag="VW361_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744640.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSRLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(14087..14545)
                     /locus_tag="VW361_001633"
     CDS             complement(14087..14545)
                     /locus_tag="VW361_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU9744641.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            14670..15057
                     /locus_tag="VW361_001634"
                     /pseudo
     CDS             14670..15057
                     /locus_tag="VW361_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4411 a         3366 c         2660 g         4620 t
ORIGIN      
        1 ataataattc aaaaaatgtt gaaagagaaa tttcattttc tcccctttca aatctagaaa
       61 gttgagattt tgatataaaa tcagctgcag catactctaa agaatatccg tttaattttc
      121 taaaatatcg aaaagcttct ccgtaatttt tcacactttc attcccttaa ctttcttttc
      181 gagcgataaa cataccatat tctttaggaa tgatcaacat accattatta aactcacttt
      241 ccaatctttt acgtattatt tcctcttcta gtgaacctat ttctgaaatt cctttaaacg
      301 attggatgta tttaactagg tcatctatac tagttacctg taactcatca tcatagagta
      361 atgtatcgac agagttaaaa tacctactca ggtacctttt accattttgt aaagtaaacg
      421 ttctattttc taaatcttga ttaacctcat ctttaaataa acttgccaaa taatttacaa
      481 ctccattttc accaaatgta gcacagtaaa aaatgcctcc ggtttttaag accctattca
      541 cctcagagag agctttagga atatcattca catgatgtag aagcatatta gcaataacaa
      601 tatcaaaagt ttcattctca aaagaaatct tttgaatatc cattatctca taattgacat
      661 tgtttctatt tccaatcact gacttcgttg attttaccat atctttagaa aaatctgtaa
      721 caatcaactg cttcatttta tctatagaat cactattact tttccacaat tctcctgtac
      781 cacatcccaa ttctagatcc tttacttcat cagtgatttg gtagttagaa aatatccaat
      841 tattaaatcc caatttattt tttgaatact tcttatgcaa ttctactcga atatcaagat
      901 tatcatgact tttatattgt tcaattactt tatcaatcat tttaaatgac ctccactcta
      961 taatttggca ttatatcaca agaataaaga tagtgttaaa taagttatat aaatgcaaaa
     1021 aaggaatatt ccgttatagc agagttgtaa cacatttcta taaagaaatt tattcctacg
     1081 actcagtttg gcatgcttaa cttcctaact caaaaacaaa gcatcgatta atttatccgt
     1141 tcttcttttg aaacagattt gaactgataa ttgctcgttt taatttaaaa agctcttttg
     1201 agcaaaactt cattttttta agagtccaac aatttctgtc tatcgctttt ctactagcaa
     1261 aaaacctacc ttgaggcaag ttttcattta tatatctaat ttcgtaacag tatagtaaaa
     1321 tgaaataagg acagtcaaat cgatttctaa caatgtttta gaagtaaagg tgtactattc
     1381 tagtttcaat ctactataaa tttgatatga gaatagtctt tctcaacatc cttatccaac
     1441 aagcatgctg tggcgtcctt cttaacttaa accaggtcaa tattctgggc ttgggctgca
     1501 tagacgcagc cacaataaca ttgacgatag atatcatact cctcacacat ctctactgaa
     1561 cgtttgtagc cttgattttt cttgaaatcg ttgggaagat agtggggcgt gtaaattttt
     1621 tgcacatcga ttccgatgct attgatagtt tgagaattct tatgaggact gatggtcaag
     1681 gctgaaccaa agtagtcaaa gcccaagtcc atagccactt gcgctgtttt atccagtcgg
     1741 tagtcaaaac aaaccttgca acggtcgcca ccttcgggct cctcctctag ccccctaact
     1801 agttttcggt attaattggg ttcgtaggga gcttctaggt actgaaccgt atttcctgtc
     1861 tgctcattaa aatcactaac aaatttcttg gtgacataga cccgcttatg gtattctgcc
     1921 ttgggatgga tattagaatt ggcaaaatag atggtcacat ctgcatactt ggtcaaatat
     1981 tctagtgtat aggtactaca aggggcacag caaacatgca cgagaatggt tggccgctac
     2041 tcattttttt cccatgcttg taccattttc tgcatgacac ggtcataatt aatcttctga
     2101 ttgggggtca tcttgcacag aatttcttct acatcgatca tgttcttctc ctttttctag
     2161 tcttatttta tcatataagt taggagagct caaatcaatt tagaagtgaa tattataaaa
     2221 agaagggtta gtcattccct ccttttgtgt tttttataag ttgttttcta tagaaagctt
     2281 acatcatccc gcccatcata cttggatcca ttgctggagc tggggctact ggttctggtt
     2341 tattggctac gactgcttct gttgtcaaaa tcaagctggc tacagatgct gcattttgta
     2401 gggctgaacg actcacttta actggatcaa tgataccttg atcaatcatg ttaacccact
     2461 cgccagttgc tgcgttgaat cctataccaa gctcagcatt tttcaaacga tcgataacga
     2521 tagatccttc aaatcctgca ttgtgagcaa tttgacgaac gggttcttcc aaagcacgga
     2581 gaacaatatt acgtcctgtt gcttcatctc ctgtcaattc caaggtagca acagctggaa
     2641 tcacattggc aagagctgtt ccaccacctg caacaatacc ttcttcaaca gctgcacgag
     2701 tagcgttgag ggcatcttca atgcggagtt tcatttcttt caactcagtt tcagttgcgg
     2761 ctccgacctt aataaccgct acaccacctg acaatttggc caagcgttct tgcaattttt
     2821 cacggtcaaa ttcagaagtt gtagtttcga tttgagactt gataaccgca acacggtgag
     2881 aaatcgcttc aggatttcct gcaccttcta caataaccgt gctatctttg tccacggtca
     2941 ctctcgctgc ttgaccaaga gcttcaattg tcgcatcttt caactcaaga ccaaggtctt
     3001 ctgtgataac tgttccgcct gttaagatgg cgatatcttc aagcatggct ttgcgacggt
     3061 caccaaaacc aggtgccttg actgctacta cgttgaaggt tccacgaatc ttgttcaaaa
     3121 caagagttgg aagagcctcg ccatccacat catccgcaat aatcaagagt ggacgattgc
     3181 tttggagaat gctttccaaa agtggcaaga tttcttggat attggaaatt ttcttgtctg
     3241 taatcaaaat gtacggattt tcaaggtcag ccaccatttt ttcgctatca gtcaccatgt
     3301 actgtgaaag gtaaccacgg tcaaactgca ttccttctac gacttcaagc tctgtttcca
     3361 taccacgtga ctcttcgatg gtgatgacac cgtctttgcc aactttttcc attgcttcag
     3421 agatgtactc accaactttt tcagaacgag aagatacggc tgcaacttga gcaatagctt
     3481 ctttattggc aacagggatg gcgttgtttt tcaaagcttc aactgctgcg gcaaccgctg
     3541 tttcaatccc acgacgaata ccgattggat ttgcacctgc tgtgacgttt ttgattcctt
     3601 cacggacgat agcttgggtc aagactgttg cagtcgtagt cccgtcacct gcgatatcat
     3661 tggttttaga agctacttct gatactaact tagcacccat attttcaaaa tggtcttcca
     3721 attcgatttc tttggcaatg gtcacaccgt cattggtaat caagggtgaa ccgaatgact
     3781 tttcaagaac gacattgcga ccttttggtc ccaaggttac tttaacagtg tctgcaagga
     3841 tatcgacacc acgaaccatg gctgaacggg catctgatga aaatttaatt tcttttgaca
     3901 tacttacttt ctccttctat tcctcaatga ttgccaaaat gttagcttcg cctacgatga
     3961 tgtacttttc atcgccatct ttgacatcaa gacctgcgtg ggcttcaact aagacacgat
     4021 ctccagtttt aacacttgga gcaaccaagt caccgttcaa ggtacgaaca ccttgtccag
     4081 tagccacaac ttgagctgtt ttggtttttt cttgggctga gcctgcaagg acaaagcccc
     4141 caacggtttg ttctttttct tctattttta agaccacacg gtcccctaat ggtttcaaca
     4201 tctgatttcc tccataatga gatagatatt attagcactc tttgaacttg agtgctaatt
     4261 cataattcta ttgtatcact tggtcagaaa tagtcaagaa aaaagtctga ctttctcaag
     4321 ataaaaagcc tgagaccaac tcagactttt taatgtttat actcaatgaa aatcaaagag
     4381 caaactagga agctagccgc aggctgctca aagcattgct ttgatgttgt ggataaagct
     4441 aacgtggttt gaagagattt tcgaagagta ttaaaatggc aattcttcct cttccaagac
     4501 taaatctgcc aaatcttggc ctgcattatt ttcacgcatg gcacgttgag cacgactttc
     4561 caagagttgg aatcctgtga caagtacttc ggtcacgtag ttcatttggc catttttctc
     4621 aaagcgacgg gtacgcaatt ctccatcaac ggaaatgaga ctacctttgg ttgcgtagct
     4681 tgccaaagtt tctgctagtc tgccccatag gaccatattg acaaaatcag cttcacgttc
     4741 accgttttgg tctttgtaac gacggttcac agcgatagtt gctcgcgcta ccgacttgtc
     4801 attgttggtt ttgtgcaatt ctggtgtaga cgttaaacgc ccaatcatga taactttatt
     4861 atacatattt tcttcctcct acttatctat tcgtaggaaa tcaaaaaagt tacagaaatt
     4921 tgtaactttt cgaggaaatt tcttattttt tatgaatcat gaaacctgtc gcctgttgat
     4981 tggccataat ggtcatatct gtaatctgaa cacggcgagg ctgactggtc acatagacta
     5041 ctgtgtctgc aatatcctga gcttgcaagg cttctattcc ttggtaaacg gacgcagccc
     5101 gctctttatc accatgaaaa cgaacagttg agaaatctgt ttcgacaatc ccaggctgaa
     5161 tggttgtcac cttgatatcc gttgcgatgg tatcaattcg cagtccatcc gaaaaggtct
     5221 taaccgcagc cttggtagct gagtaaacag cggcaccagc ataggcgtag attcctgcgg
     5281 ttgaccccat attgataacg tgaccttgat tgacttttac cattgctggc aagaaacagc
     5341 gagtaaccgc catcagacct ttaacattgg tatccaacat ggtcaacata tccaactcct
     5401 catagtcttg atagggagcc aagccaagag ccagtccggc gttgttgacc aagatatcaa
     5461 tcctccctat cgtttctaga atatcagagc aaacagtctt caccatgacc atatccgtca
     5521 catctagtgg aaaagtccag acggtttgat ttggaaagct tactgcaaac tccgacttga
     5581 ggatttctaa tctgtctatc cgtcgtcctg ttagaacgac atcctcaccc tgctccagat
     5641 aagcacgcgc aatcgcttca ccgattcctg aggttgctcc cgtaatcact acattttttg
     5701 ccatcttatt tccttctatc agatgctgac aagttcctag gcagtccagt gtttcgctgg
     5761 gtcgaacggt gttccgacaa cttggtcttc tgataattca agcaccccac gtttttgcgg
     5821 agcatttggc aaatgcaatt cacgaggact acacatcatc ccaaaactct tttcaccacg
     5881 aagttcgcct gggaaaatga aattcccttt tggcatcatg gcaccaggaa gagccacaat
     5941 ggttttcaac ccaacacgcg cattaggtgc tcctgcaacg atttgcacta tcttgtcact
     6001 tgcgactgca acttggcaga tgttgaggtg gtcactgtct ggatgagcta ccatctcgac
     6061 aatttcacca acaacaaact taggttcctt atcattaaca atttcttctg taaaaccttc
     6121 cgcctgtaat tcttggttca aacgagcgac ttgctcatct gataaaaaga cttgaccgcg
     6181 ctctgcaatt tcaaacaagc tcgaaacctc aaaaatgttc caagctactg tttccccatt
     6241 ttctttgagg aaaacacggg ctaccttgcc tttgcgttcc acattcagtt tggcatctcc
     6301 gctatttttc acgatgacca taaggacatc accgacatgt tctttgttat acgtaaaaat
     6361 cattgtttcc tttttctcct atttcaatcc tgctaaaaaa tcgttaattt gctccttact
     6421 tttacggtcg cgattgacaa aacgaccaat ttccttgtcc ttttctagaa caacaaggct
     6481 aggaattccg taaacatccc agagtttggc caaatccata tactgatctc ggtccattcg
     6541 aataaaggtg aactctggat tggtctcctc aatctctggt aaggcaggat aaatataacg
     6601 acaatcgcca caccagtctg ccacaaaaag gaagaccttc ttgcccgctt tttccactaa
     6661 agatgctaat tcttctaaac ttgctggctg tatcataaga cttcctcctc atagactagg
     6721 tcttcatttt catagacaaa ggtataatga cggccatcct caaaaataac gccaccaacc
     6781 aagctctcca gactgctttc gtaaacttga acatagaggg tcgcaattgc ccccatgtcg
     6841 gaaaaatggt ctcgcacaat ctctgtcaac tcttcctgag tcttcatgag cttacggtca
     6901 tctgcaactt ttttcgtagc aagagcaagg cttccgatac ctagcagagc caagcctgcc
     6961 atccacattt ttttagcttt cataccattc attttaacac aaaaaaggct tcaggacaaa
     7021 tgaggaagca gcagaaaagc aagtaaaaag cctcttcctt taaggaaaag gacttcttat
     7081 actaagagca aactaggaag ctagccgcag gctgctcaaa acacggtttt gaggttgtag
     7141 ataaggcgac gctgacgtgg tttgaagaga ttttcaaaga gtattattct tattgccagg
     7201 cacctaagtt gccaacgtag taaccatcag gtgtgtaggt attgcgaagc atcttacctg
     7261 atgaagccag ataatactac ttgccattgt ctttgaccca atcattcgca atcatggaac
     7321 cagaagaact cacataatac cattctccct tgtcataaac ccaagtactg actttcatgg
     7381 ttcctgagca attaaaggca aaaaaactgt ccaatatcat tcgtttttta aaagcatttg
     7441 acactacatc atctacgctg tagtacatag atacatcaaa cgtaaaagcc aaaatatcga
     7501 aaaatataca acttttaaag gcagcatttc attttttaaa gtctaacaac catagaactg
     7561 aaatcagagc aaggcatcaa tttcctactc ttagtacgtc tattttgatg gtggaagtga
     7621 agattttttt atttaacgta gacaatttcc aacttcccaa aagccacatc tccacggata
     7681 gtcaaggttt tgctggttgg ggctacagga gcgtcagcct tagctgcacc aaaggaggtt
     7741 tctactttca aatctacacg ccagtgttgt ggaacataga cggttgcatt tccgaaggcc
     7801 acttcaatat ttaaagttgc aaaatcacct agcatctctg cattatcata gtagatttta
     7861 gcatccccaa aagcgacttc cacttggtca tctacgagat cttgatcttg cttatagaaa
     7921 gtcccgctac caaaagcgac ttccttatcc gtgacgactg tttttttccc attgtaccac
     7981 catttttttt cattccagaa cttacttgaa tgcgtcagat aaccaacacc aagtaccacc
     8041 aagatgctag cccaaataag agaatgattg gtaactggta acaagtcata agcgtaattt
     8101 gcaatgatga gcgccagtaa acctgtaaaa actgccgaag tgagatgacg tctaaggatg
     8161 gactcaatgg acttataagc aaaaaaaaca atacctagta aaggccatat tttaccatcc
     8221 aaagaaggaa ttccaaaatt cccttgcagc aagatccaag ctgctaaaac caataaaaca
     8281 ataccaaatg ctttcttttt catgtttttt acctcatgtt tcttagattt tcttttagga
     8341 gggattggta atgccgtgag acatgaacct ccttgtgcgt ctgataaaag gaaatggtgc
     8401 ccgttcctga aaaggacttg tccactgagt aaatctgacg gatgtttgcg atcgttgact
     8461 tggaaactcg attaaaatag cgaggcaaga tagactccaa ctcatagagc ttgatgcgaa
     8521 cctcataagc ttccttctgg ttatgagcgt agatcttgct cccttctgtt tcaaagaaga
     8581 gaatttctga caggtctaga taatattcac ctgtcccctt gtaaaaagtc aacctcggag
     8641 cctttgactc ttgcaagagc cgttgcaagt ctgcaatttc atctgtcaaa gtgggggtct
     8701 tgatgacaat ttcagtctcc tctaaattgc cgtcaatctc aattcgtaac ttcatcacat
     8761 ctcctttctg actctactat atcaaagcta agttaggaat acaagggcaa aaaagcaagt
     8821 ggtcaatttg aagcagtaag tggttgtagg actagcttaa cttacatgtc agaataggaa
     8881 gaaaaggaat ccccacacca gaccacaagc atagccaacc aagacatcct tgggataatg
     8941 aacaccccct aaaaccctca ccaaccccag caaagctgaa aagatcaagc atactaagcc
     9001 aataggtaga ctagcatgca gacaggccat ggagatgata gttgcagaaa agacatggcg
     9061 actgggcatc gaccgtcccg aactatcctt atcaagaagg ggacagatat cccaagtttc
     9121 ataaggtctc gggtgattga ttttcttacg aaacagggac aaggccacaa aacctgatgc
     9181 aggaataagc acataaaccc caacttgctg accaagtcct agttgcaggt aagtggtgac
     9241 tagcaagatc agatagacca ggggcatggc gactgtcatc aaacgattga aactgcgtaa
     9301 taggaataaa agaattggac gactagttag tctggagctg atatttcgat accattcttg
     9361 ataatttttc atttatgctt ctcatacttt tctagaactt gttgggatgt tttccccttg
     9421 gcaagccaat ccactagctt gtccaagcga cgtatttcct gcatcagaga atcatcaatt
     9481 tcctcaatac ggacaccgca aatcttccct gtaattgcaa ttcgttcagg gacataatat
     9541 ggtgcttgtc gaaaaaaatc tccgtaagta acatccctat ccagacaagc aagaacgtca
     9601 ctcacttcat accctgtcaa ccaactggtc acttggtgaa ctgactctgc ctttccaccc
     9661 tttcgctcaa cttttgcaat caaggctaag tagacagcag caaatttcat attgtataat
     9721 ttctgactca tacttctctc tttctatgtg tactagtata aataagaaaa agaaggccgt
     9781 caagccttct tttgatttat tcttctgctt catcttctgt aaattgacta ttgtacaagt
     9841 cagcgtagaa tccaccttgc accatcaggt gaatttgatg accaaaacgc ttaaagacta
     9901 acatcggttt acccataatc tcccccttct aaataaaaat agttctctgg agaataatta
     9961 aatttctatg agaactattt tcttgattaa aaaaatccca agtgattttc tcacttagga
    10021 tcatgttcta taggttaaat taaaacccat ctacgttcgt ataaatcttt tggacgtctt
    10081 cgtcgtcttc aagaacgctg taaagttttt caaaggtttc aaggtcttcg cctgacaatt
    10141 ccacttctga ctgaggaatc atttccaatt cagtcacttg gaattcttca ataccagact
    10201 cacggagagc aacgatagcc ttgtgaaggt cagttggcgc tgtgtaaact gtgattgtac
    10261 cttcttgtgc ttctacgtca tccacatcca catccgcttc gagcaattgc tcaaagactg
    10321 cgtccgcatc ttcacctcca aatacaataa cacctttgtt gtcaaaaagg taagaaacag
    10381 aacctgaagc gcccatgttt ccgccgtttt taccaaaggc tgcacggaca ttggctgctg
    10441 tacggttaac gttagaagtc aaagtatcca caattagcat agagccattt ggcccaaaac
    10501 cttcgtaacg tccttctgta aaggtttcgt ctgtgtttcc tttggcttta tcaatcgctt
    10561 tatcgataat gtgttttggc acttgggctt gtttagcacg gtcgataacg aatttcaaag
    10621 ctgagtttga ttctggatct ggatcacctt ttttagctgc tacatagatt tctacaccaa
    10681 attttgcata tactttagag ttagctccat ctttagccgt tttcttggct acgatattgg
    10741 cccatttacg tcccattagg aatctccttt tttcacattt taatctttct tattataaca
    10801 caagtttttt tgattttcac tagaggaaat ggattttatt agcaaatcaa gctaggatag
    10861 cactttacct gctaagatgg tcttgccttt ctatctttat caacagacac tcatccacat
    10921 tcaaaaaaca aactagacca ttatctgcaa atagaaagtt tcagccaagt ttgacaaagt
    10981 cagctcaaat tactgtttga agtttgtaga tataagcgac aaaaacaatc atactgcacc
    11041 ttttgttgac agtctactcc agacatatca tagttcaagt aaatactttg aaattcaaca
    11101 gttcttatag gcgctattgt attctaagaa atcaatagaa gagtttctaa gcaaacctct
    11161 aatactcaat aaaaatcaaa gagcaaacta gaaagctagc ctcaggttgc tcaaaacact
    11221 gttttgaggt tgcggatggg gctgacatgg tttgaagaga ttttcgaaga gtataattta
    11281 cgtgttccca agatggagaa gttagactag tacactggca cttctaaaac attgctagca
    11341 attgatttgt tcatatttaa tttcattttt tccataaatg ggtattagat ataaacagca
    11401 aaatatttcc gatacgtgtc gttcttgaat ttccaatcat ctaaaacaag taaaggataa
    11461 tcaatcccct gtatatcaag gaattggcta ccctttttac ttttttacac attctgtttg
    11521 atagattcat tttaacatca cgagcatact ccaatggaaa tcgctaggca agagataaac
    11581 tttcagatat ccgcagagag atcatcgcct ctttttgtcg caagcattct cctctcctag
    11641 tcattttcta ccttatcttc tacctgagga tagagagttg ttccccaaat agaaatcgtc
    11701 cgcttacgca ctagtggcaa atcggttttt tcataaaccg tacgccacca ttcccaggca
    11761 agcccggtac actctctaat tttgacagag agattacgaa cattcccttt taaaggaata
    11821 ctagtggtaa agtgagccgt taaatcctgc ccatttctgt cccaagcctt aggagtcaag
    11881 acttccttac cttgatgatc ataggataat tcattccaag taatataata ttgggcaaca
    11941 taggcaccac tatgatccag cagtaaatct ccgtttctgt aagctgtaac cttagtctca
    12001 acatagtctg tactattttg aaaggtcgca actacattgt cacgtaaaaa agaagttgta
    12061 taggaaatcg gcaagcctgg atgatctgct gtaaagcgac tgccttcttg aatcaagtcc
    12121 tctaccatat ccaccttgcc tgttacaact cgggcacccg aacttgggtc gccccctaaa
    12181 ataaccgcct tcacttctgt attgtccaaa atctgcttcc actctgtctg aggagctacc
    12241 ttgactcctt ttatcaaagc ttcaaaagca gcctctactt catcactctt actcgtggtt
    12301 tccaacttga gatagacttg gcgcccataa gcaacactcg aaatatagac caaaggacgc
    12361 tctgcagaaa ttcctctctg ttttaaatcc tctaccgtta cagtatcttg aaacacatct
    12421 cctggatttt taacagcgtc tacgctgact gtataataaa tctgcttaaa attaacaatc
    12481 tgaatctgct tttcgcctga atggacagag ttaaaatcaa tatcaagaga attccctgtc
    12541 ttttcaaagt cagaaccaaa cttgaccttg agttgttcca tgctgtgagc cgtgattttt
    12601 tcatactgca ttctagctgg gacattattg acctgaccat aatcttgatg ccacttagcc
    12661 aacaaatcgt ttaccgctcc gcgaacactt gaattgctgg gatcttccac ttggagaaag
    12721 ctatcgctac ttgccaaacc aggcaaatca atactataag tcatcggagc acgatcgacc
    12781 gcaagaagag tgggattatt ctctaacaag gtctcatcca ctacgagaag tgctccagga
    12841 tagaggcgac tgtcgttggt agctgttaca gaaatatcac ttgtatttgt cgacaagctc
    12901 cgcttctttc tttcgataac aacaaactca tcgggtagct gattaccctc tttgatgaaa
    12961 cgattttcaa tactttctcc ctgatgggtc aagagtttct ttttatcgta attcatagct
    13021 agtataaagt catttactgc tttatttgcc atcttctacc tcctaataag ttcctggatt
    13081 gagttgcata aactcagact tgttcagcga aatcagccgt ggttggacta agtgatccaa
    13141 aatttcctcg tacaattctt ctgagacatt gcgtcgccgt ctggctagat aagaagtcgg
    13201 aataaccgta ttatccaaca taaatacctt atctaagtca atcaaggttg gtcttgtaaa
    13261 aggattacga gctagatccg gctcttctat cataaagttc ttgaccaaac gtctggtcaa
    13321 gagagctggt ttgaaggtct gatttttaac caactctttg tttttagtca tgctgttgtc
    13381 aatacagata tacatatgat tcttcacagc caaatcgcta ctaatagtcg gaaaaggcaa
    13441 ataaagagct acaacatctc ctctcttaat caagcaagag cacccccttt tctcctaatg
    13501 taacatagac aggattgacc aagtcttctg attgactcag aatttccaaa gtttgagttt
    13561 ggcgcgctgt caatttagta gcatcttgtc tcttcaatac aaaatgcttg tcgccaataa
    13621 ccttgacaat ataatccttc tccaaagctg actggtaaat ccacatcaga tgttgtctgt
    13681 cctgagaact caagcgagaa ggattttcaa gcctcccgat agtctgataa aaatcaaaaa
    13741 caggagctaa ctcctgccaa tctgattggc tagttgtcaa ggctagaaaa agggctttgc
    13801 gagctgatac ttcttggtta gccttgagag ttactttccc ctccaagttt tttagaaatc
    13861 gggaaactcc agaaagcaaa tttttctcta actgcgagaa ataaaaacct ttcgttccca
    13921 gacataagtc tttcatgtcg ctttctctag caaataagag ctcaaacatt tgatagtaaa
    13981 agaaaaatat ctggcactgg gtcgcgctca tcttttcctt atcggcttct ttttttaacc
    14041 agagcaaggg cgacaggtag ctggattgag acatttcctc tacctcctac tcttttttaa
    14101 ctggagcatc tgcactagct gccacttctt ttgactggat actttcccac tggttaatct
    14161 cctctgagat aagaccttcg catgtcttga caaatagggc aaaagccttg gtctttcctg
    14221 catatttctc cgtttggcat tgatagagga atttttcttt ctccaggagt tgcgcagttt
    14281 tttggtaaga aatccaattt tcctttgcat tatacaaatt gataatcccc tcacacagca
    14341 agccgagact ggataaggca accgaaatca aacggtagcg atcacctggc ataggaatag
    14401 cacaaaagac agctatgagg aaacctgcca cgatttctgt tatttttaat accttatagc
    14461 gtctacgatg ttgaacgctt ttctttaaaa aatgagctat ctgtacgtct aatcgctctg
    14521 tcaggtacat ttcttctggc gtcatattcg taactccttt catttacttt gataaccata
    14581 gtataacata tttgaatatc aaagtatagt aaaaactgga ctataactta ttagacttcc
    14641 tgcgaaacaa aatatggtat agtagttcta tgaattatga agcaagtaaa caactaactg
    14701 atgcacgatt taagcgtctt gttagtgttc agcgtaccac ttttgaagag atgttagctg
    14761 tattaaaaac agcttatcaa aaaagtcgga caagctggta aaatcttggc tgacagtggt
    14821 tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc cagcaaactc
    14881 aagccgctaa cagttgaaga taaagcctat aaccatgcgc tatctaagga gagaagcaag
    14941 gttgagaaca tctttgccaa agtagaaatg tttaaaatgt tttcaacaac ctatcgaaat
    15001 catcgtaaac gcttcggatt acgaatgaat ttgattgctg gtattatcaa tcatgaa
//
LOCUS       DAVKMO010000047        14281 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVKMO010000047 DAVKMO010000000
VERSION     DAVKMO010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.047"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            81..878
                     /locus_tag="VW361_001635"
     CDS             81..878
                     /locus_tag="VW361_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU9744642.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1026..2285
                     /locus_tag="VW361_001636"
                     /pseudo
     CDS             1026..2285
                     /locus_tag="VW361_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2381..3655
                     /locus_tag="VW361_001637"
     CDS             2381..3655
                     /locus_tag="VW361_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU9744643.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIENFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKEHDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKVQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3665..4543
                     /gene="truB"
                     /locus_tag="VW361_001638"
     CDS             3665..4543
                     /gene="truB"
                     /locus_tag="VW361_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU9744644.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAADLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4784..5086
                     /locus_tag="VW361_001639"
     CDS             4784..5086
                     /locus_tag="VW361_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9744645.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKHQS
                     VMADLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5194..5832
                     /gene="udk"
                     /locus_tag="VW361_001640"
     CDS             5194..5832
                     /gene="udk"
                     /locus_tag="VW361_001640"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU9744646.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5960..7300
                     /locus_tag="VW361_001641"
     CDS             5960..7300
                     /locus_tag="VW361_001641"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU9744647.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSRIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7278..7490
                     /locus_tag="VW361_001642"
     CDS             7278..7490
                     /locus_tag="VW361_001642"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU9744648.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7487..8362
                     /locus_tag="VW361_001643"
     CDS             7487..8362
                     /locus_tag="VW361_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU9744649.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVGLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8355..9170
                     /locus_tag="VW361_001644"
     CDS             8355..9170
                     /locus_tag="VW361_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU9744650.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLVYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9163..9594
                     /locus_tag="VW361_001645"
     CDS             9163..9594
                     /locus_tag="VW361_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9744651.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9601..11268
                     /gene="recN"
                     /locus_tag="VW361_001646"
     CDS             9601..11268
                     /gene="recN"
                     /locus_tag="VW361_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU9744652.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11270..11998
                     /locus_tag="VW361_001647"
     CDS             11270..11998
                     /locus_tag="VW361_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU9744653.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12077..13900
                     /gene="lepA"
                     /locus_tag="VW361_001648"
     CDS             12077..13900
                     /gene="lepA"
                     /locus_tag="VW361_001648"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU9744654.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14059..14139)
                     /locus_tag="VW361_001649"
                     /pseudo
     CDS             complement(14059..14139)
                     /locus_tag="VW361_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         4227 a         2597 c         3396 g         4061 t
ORIGIN      
        1 ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa
       61 aaaagattta ggagtttatt atggtttctt cagaatttat ttcaaagatt gaatttgctt
      121 gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatgt
      181 tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc agttggggct gacttgatta
      241 ataaaattgc accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg
      301 cctacattgt ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg
      361 gtagtttctt aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct
      421 tgttcaacct tatcggagcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg
      481 cgaatctgac acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa
      541 atgaattggt tttgcttgag gcgattttgg caaatatttt cgtaaatatt gcgattctgt
      601 catttatttt ggtcaaagat ggtggtgcca aactttggct tgtgttgtca gctatttaca
      661 tgtttgtatt cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga
      721 aattcagtgt tgctgcggat tcaattgcca acttcggtgt tggaaatatg cttcgccact
      781 ggggtgtgac tttcatcgga aactttatcg gaggaggcct cttgatgggt cttccatatg
      841 ccttcctcaa taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg
      901 tgcttttttc attttcaaaa taagataata gctatttctt atatcaaaat atagaaaact
      961 gatatttgta aactataact caaggtgcta caatatcctt aataaaataa tatggaggtc
     1021 accttatgac tcgtgatttt aaatttgaaa ctctacaact acatgctgtt caagttgtgg
     1081 ctccagctac taagtctcgt gcagtgccga tttatcaaac aacatttttt gtttttgatg
     1141 acacgtagga aggtgccgat atgtttgcct tgaggaaacc agggaacatt tatactcgta
     1201 tcaccaatcc tacaacagct gcccttgaag gtggtgttga agcgctagca acagcatcag
     1261 gtatgactgc agtgacttat acgattttgg cgattgccca tgctggtgac catgtagtgg
     1321 ctgcttcgac tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg
     1381 gtatcacaac aacctttgtc gatattgata atttggagga agtagaagca gctatcaaag
     1441 acaataccaa gcttgtcttg attgaaacct tgggtaaccc cttgattaat attccagacc
     1501 tggaaaaact ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt
     1561 ttgcaacacc ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg
     1621 cgactaagtt tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggta
     1681 gttttgactg gacggcttca gggaaattcc ctcaatttgt tgacgagggt ccaagctgcc
     1741 acaatttgag ttatactcgt gatgtgggtg cagcagcctt tattatagct gttcgagttc
     1801 aattgcttcg tgatacaggt gcagccttgt caccattcaa tgctttcctc ttgctacaaa
     1861 gacttgaaac cctttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg
     1921 attttcttgt caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc
     1981 cttatcatgc cttggctgag aaatacttac caaaaggtgt gggctcaatc tttaccttcc
     2041 atgtcaaagg tggggaggcc gaagcccgca aggtcattga taatttggaa atcttctcag
     2101 accttgctaa cgtggcagat gccaagtctc ttgttgttca tccagcaaca accactcacg
     2161 gtcaattgtc agacaaagac ctagaagccg caggtgttac accaaaccaa atccgcttgt
     2221 cgatcggact tgaaaatgta gaggatttga ttgaagattt gcgcttggcc ttggaaaaaa
     2281 tttaaagtaa aagaagataa acagtggttt tcgactcgct gtttttgatt ttccttcatg
     2341 catgatataa tggttacaga agtctagaaa gaggaatgta atgaacgaaa tcaaatgtcc
     2401 caactgtggg gaagtcttta cagtaaatga aagccagtat gctgaacttt tgtcccaagt
     2461 gagaacggca gagtttgata aggaactaca cgataggatg aggcaggaac tggccttggc
     2521 tgagcaaaag gctatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc
     2581 gcaattacag agtcagatcg aaaactttga tacagaaaaa gaattggcca agaaagaagt
     2641 tgaacagaca agccatcagg ccttattggc taaggacaag gaagtacagg ctttggagaa
     2701 ccaattggcc actttgcgtt tggagcatga aaatcaactg caaaagaccc tttctgacct
     2761 agaaaaagaa catgatcagg tcaaaaatca gctcctcttg caagaaaagg aaaatgagtt
     2821 gtctttggct tctgttaagc aaaactatga agcccagctt aaagcagcta gtgaacaagt
     2881 cgagttttat aagaatttta aggttcaaca atctacaaaa gcgattgggg aaagcctaga
     2941 acagtatgca gagagtgagt ttaacaaggt tcgtagtttc gcctttccaa atgcttactt
     3001 tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg
     3061 tgatgaaaat ggagttgaaa tcatttctat catgtttgag atgaaaaacg aagcggacgg
     3121 aacagagaag aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga
     3181 gaagaactgt gagtatgccg ttttggtgac catgcttgag gctgataatg actactttaa
     3241 cacagggatt gttgacgtca gtcacgagta tgaaaaaatg tatgttgttc gtcctcaatt
     3301 ctttatccag ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca
     3361 ggagttggcc ttggttcgcg agcaaaatat tgacattacg cattttgagg aagacttgga
     3421 tgcctttaag ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc
     3481 tattgatgaa atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgaccac
     3541 atctgaaaac caactccgtt tagctaacaa caaattggaa gatgtctctg ttaaaaaatt
     3601 gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc
     3661 aaaaatgaac ggtattatca acttaaaaaa agaagcagga atgacctcgc atgatgcggt
     3721 ttttaaactg cgtaagattt tgggaaccaa gaaaattggt catggtggaa ccttggatcc
     3781 ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat
     3841 gcaggacgag gggaagatct atgaggggga aattactctg ggctattcca cgacgactga
     3901 ggatgctagt ggggaagtgg tcgcagaaac ccctgttttg tctcccttgg atgaaaagct
     3961 tgttgatgaa gcgattgcta gcttgactgg gcctattacc cagattcccc ctatgtattc
     4021 ggcagttaag gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga
     4081 gcgtccagaa cgtcaggtga ccatttatca atttgagcga acaagtccga tttcttatga
     4141 tggccaactt gcccgattca cttttcgtgt aaaatgcagt aaagggactt acatccgtac
     4201 tttgtcagtt gatttgggtg aaaagcttgg ttatgcggct catatgtccc atttgactcg
     4261 tactagtgct gctgacttac aattagaaga cgctcttgcc ttggaggaaa ttgctgaaaa
     4321 agtagaggct gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt
     4381 caaagttttc ctaactccag aagaggctac agaagttcgc tttggtcgtt ttattgagct
     4441 agaccaaacg gataaagaac tggctgcctt tgaagatgat aaattgttag ccattctaga
     4501 aaaacggggc aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa
     4561 atcgggtgat agataacaat tgcttgataa aaccccatac taatagtaga atggttttgg
     4621 gaattataat attccaattg ttgcgagttg taggtactca aataatctat atagaaattt
     4681 agaggtgtga aatgaagcaa tttaaaattc tttcagataa atatttagag tccattacag
     4741 gttctggtgg gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt
     4801 tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag
     4861 tcacctgttt cgtcttgcta tacaaaattt agacagaaat gaaaaacacc aatcggtcat
     4921 ggccgatttg agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa
     4981 gtctgtcatt gattttggtt tatggattgc caaagctcct agccaggaaa gagggagact
     5041 ggctttcttg cagatgcttg ctcaaaccct acagggcttt cgttaaaact gtcgaacatc
     5101 agagggaaga ctctggtgtt ttttgctgat gagactataa attttgtaaa aaatgtgata
     5161 gaatagacga cggataaaat aacggaggat agcatgcaaa atagaccaat cattattgga
     5221 gtgacaggtg gttctggtgg tggtaaaacc agtgtttcaa gagccatttt atcgcatttt
     5281 cctgatgaaa agatttccat gattgagcat gattcatact acaaggatca gtctcatttg
     5341 acctttgaag agcgtgtcaa aaccaactat gaccatcctt ttgcctttga tacagacttg
     5401 atgatcgagc agattaagga attgttggca gggcgtccgg tggacatccc gacctacgac
     5461 tatacagagc atacacggag tagcaagacc tatcgtcagg agcctcaaga tgtctttatc
     5521 gttgagggca ttttggtctt ggaggacaag cgtctgcgcg atttgatgga tatcaagatt
     5581 tttgtggata cggatgacga tgtgcgtatt attcgtcgta tcaagcgtga tatggaggag
     5641 cgtggccgta gccttgatag cgttatcaac cagtacttag gtgtggtcaa accaatgtac
     5701 caccagttta tcgagtcaac taagcgttat gctgatatcg tcattcctga aggggttagc
     5761 aataccgtgg ctatcgacct gttgacgacc aagattgcaa agattttgga agaagctcga
     5821 aacagcaaat aatcacatgt ggaggccttg cctccttttt ctatttttcc ctcataatgg
     5881 tacataaatg gagattttta ggcatatttt tggtataata atacccatga aagagcaagt
     5941 aaatgaatag taggtggaga tggaaaagta tttatcggta acaactttga ccaagtatct
     6001 gaaaatgaaa ttcgataaag acccatactt ggaacgggtc tatttaactg gtcaagtttc
     6061 caactttcgt aaacgaccta ctcaccaata tttctcccta aaggatgacc atgcagttat
     6121 tcaagcgacc atctggtcta ggatttatca gaaattaggg tttgacctgg aagaaggaat
     6181 gaagatcaat gtgattgggc gtgtacaggt ctatgaacca agtggtagct actccatcat
     6241 cattgaaaaa gctgagcctg atggggttgg ggcgcttgcg attcagtttg aacaacttaa
     6301 gaaaaaattg acagaagaag gcctgtttca agaacgcttc aagcaagctc tgccccaatt
     6361 ttctaagaga attggtgtag taaccagccg tagtggagct gttattcgag atattatcac
     6421 gaccgtcagc aggcgattcc caggtgttga catccttctt tatccgacca aggttcaagg
     6481 tgaaggggct gcggaggaaa ttgctagaaa tattgcgcgt gctaatcaac gggacgattt
     6541 ggatttgctc attattggtc gtggaggtgg ttctattgag gatctctggg cctttaacga
     6601 agaaattgtg gtacgagcta tttttgaatc tcgtttgcca gttatctcta gtgtggggca
     6661 tgagacggat gtgaccttgg cagattttgt ggcagatcga cgcgctgcaa cgccaacagc
     6721 ggcggctgaa ctggcaacac ctgtgaccaa gttggatgta ttagctcatt tgcaaaatca
     6781 ggaaaaacgg atggtaacgg cagtccgaaa tgttctatct aagaaacaag aggctttgaa
     6841 aaaatgcagt cagtctgtta tctttagaca acctgagcgc ttgtatgacg gttatttgca
     6901 acgcttggac caactgcaac tgcgtttgaa acaaagtttg cgaactcgga tttctgataa
     6961 caaacaatta gttcaagcaa gaactcatca attagtacaa ttatcacctg ttaccaaaat
     7021 ccaacgctat caagaccgtt taggacagtt ggacaagctc ttaggtagcc aaatggcgtt
     7081 agtttatgac gccaaggttg ctgaggccaa gcgactttcg gaagctttgc tcatgttgga
     7141 tactagccga atcgtggcgc gtggttatgc tattgtcaaa aaagaagagt ccgttgtaga
     7201 ttcggttgag agtttgaaga aaaaagacca agtaacgctt ttgatgcgag atggtcaagt
     7261 agaattagag gttaaagatg tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg
     7321 aaaccattgt ccaaagtttg gaaaatggtg aaattgctct ggaagatgcg attactgcct
     7381 ttcaaaaggg catggtcttg tcaaaagagc tccaagctac gctggacaag gctgaaaaga
     7441 ccttggtcaa ggtcatgcaa gaagacggaa cagaaagtga ttttgaatga aaaagcaaga
     7501 aaaattagct cttgtcgagt cggctttgga agatttttat ggagaccagc agtttgcctc
     7561 tagtttacgg gagtctgttc tctattctat tcatgctggt ggcaagcgta ttcggccttt
     7621 tctcttgtta gaagttctgg aagccttgca ggttaccatc aaacctgctc acgcgcaggt
     7681 agctactgcc ttggagatga ttcatacagg gagcttgatt cacgatgacc ttcctgctat
     7741 ggatgatgac gattatcgaa gagggcggtt aaccaatcac aagaaattcg gtgaagctat
     7801 ggccattttg gctggagatg ccttattctt agacccatat gccttgattg cgcaggcaga
     7861 tttgccaagt cagatcaagg tgggcttgat tgccaactta tcccttgctt caggtagtct
     7921 gggtatggtg gcagggcaag ttttggatat ggagggcgaa caccagcact tgtctctgga
     7981 agaacttcag actattcatg ccaataagac tgggaagtta ctagcctatc ccttccaagc
     8041 ggcagctatt atagctgaat tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga
     8101 attgattgga cttgcttttc aagtcagaga tgatgtactg gatgtgacgg ctagttttga
     8161 ggaaatcggc aagacacctc aaaaggatct gcaggcagaa aaatcaacct atcctgcctt
     8221 gttgggcttg gaagagtcca ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa
     8281 attagaagaa attgcccagc agcttccctt tgaaacagaa tcgattgtaa gtgtagtaga
     8341 aagtttgaga atcaatggct aaggaaagag tggatgtact agcttataaa caggggttgt
     8401 ttgaaacgag agagcaggcc aagcgaggtg tgatggctgg cctagtcgta gcagtcctta
     8461 atggagaacg gtttgacaag ccaggagaga aaattccaga tgacaccgaa ttaaaactca
     8521 agggggagaa actcaagtat gtcagccgtg gtggtttgaa actggaaaag gccttgcagg
     8581 tctttgattt gtcggtggat ggcgcgacta cgattgatat cggggcctct actggaggtt
     8641 ttaccgatgt catgctacag aatagtgcca agttggtctt tgcagtcgat gttggtacca
     8701 atcagttggc ttggaaatta cgccaagacc cacgagttgt cagcatggag cagttcaatt
     8761 tccgctatgc tgaaaagact gatttcgagc aggagccgag ctttgccagt attgatgtga
     8821 gtttcatttc ccttagtctg attttgccag ccttgcaccg tgtcttggct gatcaaggtc
     8881 aggtggtagc acttgtcaaa cctcagtttg aggcaggacg tgagcagatt gggaaaaatg
     8941 gaattattcg agatgctaag attcatcaga atgtccttga atctgtaaca gctatggcag
     9001 tagaggcagg tttttcagtc cttggcttgg acttttctcc catccaaggt ggacatggaa
     9061 atattgaatt tttagtgtat ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg
     9121 agattaaaga agcagtagag agggcgcata gtcaatttaa aaatgaataa aaaagagaga
     9181 cttgaaaaaa ttagaagatt ggtgacagat tatcaaatcg gcacgcaaga agaaattgta
     9241 gaacatttga aagaagcagg tatcactgcc actcaggcga cggtatcccg agatatcaaa
     9301 gagttaggta ttgtcaaaat tcctttgaga gacaacacct atgtctacga attgccaaaa
     9361 tcaatcgtaa aaagtctgca actggctgaa gacaatatcg aatcggctga attgatggat
     9421 aagatgatca atctccaagt tattccagga aatacggctt ttgtaaaagc tcagttaatc
     9481 gagacttttg cagacaagat ttttagctgt ttgactgatg atagctcgat tttagtcatt
     9541 gccagaagtg gaagtctagc agaggaaatc tttgaacaag taaaaaattg gtaggtctat
     9601 atgttacttg aaatttcgat aaaaaacttt gccattattg aggctatttc cctcaatttt
     9661 gaaaagggga tgactgtcct gactggtgaa acgggtgcag ggaagtcgat tatcattgat
     9721 gccatgaata tgatgttggg agctcgtgcg acgacagatg ttattcgtca tggtgcacca
     9781 aaggcagaga ttgaggggct tttctcagtt gagaatagtc gtcttttaca ggaaattttt
     9841 gatgagcaag gtttagaatt aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat
     9901 ggtcgtagta tcagccgtgt aaatggtcag atggttaatc tgtctgtttt gcgagctatt
     9961 gggcaacatc ttgtagatat tcatggtcag catgaccatg aggagttaat gcgtccccaa
    10021 ctgcatatcc agatgttgga tgaatttggt gatgccgctt tttgggactt gaaagaaacc
    10081 tatcaaacga gttttgatgc ctatcggaaa atgcgcaagc aggttctgga agtcaagaaa
    10141 aaccaacagg aacacaaggc acgtatcgaa atgttggaat ttcaaatggc agagattgag
    10201 gcagcaaact tgcaggctgg agaagacttg gctctcaatc aagagcgaga taaactcctc
    10261 aaccacaaaa atattgcgga tacactgacc aatgcctaca gtatgttgga caatgaagat
    10321 ttttcaagtc tggccaatgt tcgttcagct atgaatgaca tggaaagtgt cgaagagtat
    10381 gatcctgaat accgtgaaat ttcaagctct ctgtctgaga cctactatgt tttagaagac
    10441 attagcaaac gtttggaagc tatcattgag gaccttgatt ttgatggcaa tcgcctgatg
    10501 caggttgaga atcgtttgga cctccttcat actattactc gtaagtatgg tgggactgtt
    10561 gatgatgttt tgctttattt tgccaagatt acggaagaat acaatctctt gacaggcaat
    10621 aatctttcgt ctgaggacat ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat
    10681 ttggcaggtc aacttgcttc tgctcgtcat aatttggctc agcaactcga agctgagatt
    10741 aaacaagaac tgcaagatct ttatatggaa aaagcccagt ttcaggttcg ttttagtaag
    10801 ggaaaattca gtcgtgaggg aaataaaatg gttgagtttt atatttcaac caaccctgga
    10861 gaagacttta aacccttggt taaggttgct tctggagggg aattatctcg tctcatgtta
    10921 gccattaagt ctgccttttc acgtaaagaa ggcaagacta gcattgtctt tgatgaggtg
    10981 gatacgggag tttcaggtcg tgttgctcaa gctattgctc agaaaattca taaaattggt
    11041 cagcatggtc aggttttggc tatctcccat ttgccacaag taattgcgat tgcagattat
    11101 caattcttta ttgagaagat tagtaatgac cattcaacgg tttcgactgt tcgtctcttg
    11161 acggtcgaag agcgagtgga ggaagttgcc aagatgttgg caggtgatga tgtgacagaa
    11221 gcagccctga cgcaagccag agaattgttg agaaacaggg agaaataaga tgacagatta
    11281 ttatgtaatt ggagatgttc acggaaaagc tgggatgctg gaagaccttc tcaaaacctg
    11341 ggatggtcag ccccagttgc tctttctagg tgatttgatt gacagaggtg aggatagtca
    11401 ccgtgttctt gaaatggtca aggacttggt ggacaatcaa ggggctatct gtttgtccgg
    11461 aaaccacgag tatatgtttt tgacttggct agatgaccca gaagaaagtt atgaccatta
    11521 tagtcgcaat ggtggagata caaccattaa ctctatccta ggtcgtccct tggatgcacc
    11581 agttgatgga gtagaagatg ccaagcgggt tgccgctgaa gcgtcagact tggtcgaatt
    11641 cattcgtcaa atgccatttg tagtagagac agacaagtat atatttgttc acgcaggtat
    11701 tgatttgact ttggacgact ggcatgaaac aacagattat aaaaaagtat ggcttagaaa
    11761 accattccac ggagctgaaa atcatactgg aaaaaccatt gtcttcggtc atacaccggt
    11821 ctatggtttg ttacagcaag aacgcggtac atctgagctt tggactacag aagatggcaa
    11881 gattggaatg gatggaggag ctgtttatgg tggtgtcctt cacgggattg tctttacaga
    11941 ccaaggaatg acagaacacc actttatcga aaatgacggc tttgtcgctg aagattagta
    12001 ctcctagcag ggtatggtct tgtcaaaata tcaaaaacaa tttataataa atagataccc
    12061 tgaaaggaag agaatcatga acttagaaga attgaaaaaa cgacagggga agatccgtaa
    12121 cttctctatt atcgcccata ttgaccacgg gaaatcaact ctagcagacc gcattttgga
    12181 aaaaacagag acggtttcaa gtcgtgaaat gcaggcccag cttttggata gcatggatct
    12241 agagcgggaa cgtggaatta ctattaagtt gaatgccatc gagttgaatt acactgcaaa
    12301 agatggggaa acttatattt tccacttgat tgacacacca gggcacgttg actttaccta
    12361 tgaagtttca cgttcgctag ctgcctgtga gggtgctatt ttggtggtcg atgcggctca
    12421 aggaattgag gctcaaactc ttgccaacgt ttatctggct ttggataatg atttggaaat
    12481 catgcctatc attaataaaa ttgacctgcc ggctgcagat ccggagcgcg tgcgtacaga
    12541 gattgaagat gtgattggtt tggatgccag tgaagcagtt ttggcttctg ccaaggctgg
    12601 tattgggatt gaagaaatcc tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga
    12661 tgtgacggcg ccacttaagg ccttgatttt cgactctgtt tacgatgctt accgtggggt
    12721 tatcctccaa gtgcgtgtca tggacggagt ggtcaaacct ggtgataaga ttcagctcat
    12781 gagcaatagt aagacctttg atgtggccga agtcggtatt tttacaccaa aagcggttgg
    12841 tcgtgatttc cttgcgactg gtgatgttgg ttacattgcg gcgtctatca agacggttca
    12901 ggatactcgt gtgggtgata ccgttacctt ggcaaccaat cctgcggcag aaccattaca
    12961 tggttataag cagatgaatc ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa
    13021 gtacaatgac ctgcgtgaag cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt
    13081 tgaaccagaa acatctcagg cacttggatt tggtttccgt tgtggatttc ttggacttct
    13141 ccatatggat gttattcagg aacgtttaga gcgtgagttc aatattgacc tcatcatgac
    13201 agctccgtct gttatttaca aagttaattt gaccgacggt gagtctatgg atgtgtctaa
    13261 cccatctgag tttccagacc caactaagat tgcgaccatt gaagagcctt atgtcaaggc
    13321 gcaaatcatg gtaccacagg agttcgtcgg agcagtaatg gagctagctc agcgtaagcg
    13381 tggggacttt gtgactatgg actatattga tgataaccgt gtcaatgtta tctatcaaat
    13441 tcctcttgct gaaattgtct ttgacttctt tgataaactt aagtcttcga cacgtggtta
    13501 tgcaagcttt gactacgaat tgtcagaata tcgcccatct aagctggtga aaatggatat
    13561 ccttctcaat ggagataagg tggatgccct cagctttatc gttcacaagg actttgccta
    13621 cgaacgtggg aaactcatcg ttgataaact caagaaaatc atccctcgcc aacaatttga
    13681 agttccaatc caagcggcta ttggacacaa gattgtcgct cgtactgata tcaaggccct
    13741 tcgtaagaac gtacttgcta aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct
    13801 tgaaaaacaa aaagctggta agaaacgcat gaaatccatc ggatcagttg aagttccgca
    13861 agaagccttc ctcagcgtct tgagtatgga tgaagaataa gttatcagaa atgcctttcc
    13921 ttgttcacag gaaatttata taaaaatcaa tagtaaagca ggcttagatg gtctgctttt
    13981 ttagttttta tactcttcga aaatctcttc aaaccacgtc agcgtcgcct taccgtatgt
    14041 atggttactg acttcgtcag tttcatctac aacctcaaaa ctgtgttttg aacaacctgc
    14101 ggctagcttc ctagtttgct ctttgatttt cattgagtat tagaacagaa aaaatgcttg
    14161 gagtatttgt ttgtgtgttt acttttatat aacaaactat aaacacaaca aaaatataaa
    14221 aaaagagaca aaaaaagaac agaaagtaat taacaacgat ttcatatagt gttatactta
    14281 t
//
LOCUS       DAVKMO010000048        14208 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVKMO010000048 DAVKMO010000000
VERSION     DAVKMO010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14208
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.048"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..874
                     /locus_tag="VW361_001650"
     CDS             <1..874
                     /locus_tag="VW361_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU9744655.1"
                     /translation="KRERRKTEIVQELMTEFSLDLLLKAIKLARSTYYYHLKQLDKPD
                     KDQELKAEIQSIFIEHKGNYAYRCIHLELRNRGYLVNHKRVQGLMKVLNLQAKMRQKR
                     KYSSHKGDVGKKAENLIQGQFEGSKTMEKCYTDVTEFAIPASTQKLYLSPVLDGFNSE
                     IIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQAS
                     MSRKGNSQDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAIVDYIDYYNNKRIKVKL
                     KGLSPVQYRTKSFG"
     gene            complement(1001..1204)
                     /locus_tag="VW361_001651"
     CDS             complement(1001..1204)
                     /locus_tag="VW361_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744656.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(1197..2279)
                     /locus_tag="VW361_001652"
     CDS             complement(1197..2279)
                     /locus_tag="VW361_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9744657.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(2405..3187)
                     /locus_tag="VW361_001653"
     CDS             complement(2405..3187)
                     /locus_tag="VW361_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU9744658.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGTHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(3187..4530)
                     /locus_tag="VW361_001654"
     CDS             complement(3187..4530)
                     /locus_tag="VW361_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU9744659.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4629..5945)
                     /locus_tag="VW361_001655"
     CDS             complement(4629..5945)
                     /locus_tag="VW361_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU9744660.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            6139..7365
                     /locus_tag="VW361_001656"
     CDS             6139..7365
                     /locus_tag="VW361_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU9744661.1"
                     /translation="MKSNRYIIAFTGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7564..9138
                     /locus_tag="VW361_001657"
     CDS             7564..9138
                     /locus_tag="VW361_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9744662.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVSPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGGK"
     gene            9402..10190
                     /gene="codY"
                     /locus_tag="VW361_001658"
     CDS             9402..10190
                     /gene="codY"
                     /locus_tag="VW361_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU9744663.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            10190..10765
                     /locus_tag="VW361_001659"
     CDS             10190..10765
                     /locus_tag="VW361_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9744664.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10847..10932
                     /locus_tag="VW361_001660"
     tRNA            10847..10932
                     /locus_tag="VW361_001660"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10881..10883,aa:Leu,seq:aag)
     gene            11216..12346
                     /gene="ugpC"
                     /locus_tag="VW361_001661"
     CDS             11216..12346
                     /gene="ugpC"
                     /locus_tag="VW361_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU9744665.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12847..13605
                     /locus_tag="VW361_001662"
     CDS             12847..13605
                     /locus_tag="VW361_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9744666.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13692..14204
                     /locus_tag="VW361_001663"
     CDS             13692..14204
                     /locus_tag="VW361_001663"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU9744667.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
BASE COUNT         4284 a         2590 c         3096 g         4238 t
ORIGIN      
        1 aaaaagagaa agaagaaaga cagaaattgt tcaagaatta atgactgagt tttcgttaga
       61 tcttcttcta aaagccatta aactagctcg ttcgacctac tactatcact tgaaacagct
      121 agacaaacca gataaggacc aagagcttaa agctgaaatt caatccattt ttatcgaaca
      181 caagggaaat tatgcttatc gctgtattca tttagaacta agaaatcgtg gttatctggt
      241 aaatcataaa agagttcaag gcttgatgaa agtactcaat ttacaagcta aaatgcgaca
      301 gaaacgaaaa tattcttctc ataaaggaga cgttggtaag aaggcagaga atctcattca
      361 aggccaattt gaaggctcta aaacaatgga aaagtgctac acagatgtga cagaatttgc
      421 cattccagca agtactcaaa agctttactt atcaccagtt ttagatggct ttaatagcga
      481 aattatcgcc tataatcttt caacttcacc caacttagaa caagtacaaa caatgttgga
      541 acaggcattc acagagaagc actatgagaa tacgattctc catagtgacc aaggctggca
      601 atatcaacac gattcttatc atcggttcct agagagtaag ggaattcaag catccatgtc
      661 acgtaagggt aacagccaag ataacggtat gatggaatct ttctttggga ttctgaaatc
      721 ggaaatgttt tacggttatg agaagtcgtt tcagtcgctt aagcaattgg aacaagctat
      781 tgtagactat attgattact acaacaataa acgaattaag gtaaaactaa aaggacttag
      841 ccctgtgcaa tacagaacta aatccttcgg ataaattaat tgtctaactt tttggggtca
      901 gtacagaaaa actttgatac tatgcgtttt attgtgggaa gattttcctc attttctagt
      961 gaaattgaac tttttctaac atcttttgat agatgacttc ttaatcaatt atcatttcca
     1021 ttgttgtttc ttggggtttc atcccttgtc tttgataaaa gcggagagca ccctcgttat
     1081 cattccagac acttagggtt agattattgc agccaatttc tttagcataa tagcagaaaa
     1141 atgacaataa aatagcccct agatattttg aaaggaaagc ataggggcta tatagtttaa
     1201 tcaaaataaa gcaaatcttt gctggtgctt gtaaagaggt cgaagccatc cttggtaaca
     1261 acaccgcagt cttcaatacg aacaccgact ttaccaggga tatagatacc tggttcaaca
     1321 gagaagcaca tgccttcttc gatgaccatg tcgtttcctt ccatgataga tgggaattca
     1381 tggacatcca taccgatacc atgcccgaga cggtggttga agtactcacc ataaccagct
     1441 ttttcgatga cctcacgggc agcgcggtcc acttcatgag cagtcacacc tggcttgata
     1501 aagtcaagag cagcttgttg ggcttcaaga gtcaagttgt aaatatcttt cttgaattgg
     1561 tctggtttgc cgacagcgac tgtacgagtc atatctgacg catagccatt gaccagaaca
     1621 cccaggtcaa agaggagaag agcatcattt tcaaccttat tagctgctgg aatgccgtgt
     1681 ggattcgcag cattatcacc agtcaagacc atggtatcaa agctcatttc gtaaccttca
     1741 cgtttcatgg caaagtcaat ttgtgcgatg atatctgtct cagtcttatc aagagaaata
     1801 ttgtcaaaac caacatgaac agccttgtca gcataaagac ctgcaaccat cattttttgt
     1861 acttcatcag ctgatttgat gaggcgcatg cgttggatac gaggagtgag gttttcaaac
     1921 tcagcagttt caaaaactgt tttcaaacca tggtatttgg tcaagatgag attgtcaaac
     1981 tcaacagcga cacgtttgaa gtcaagttgt ggaagagcat gtttgatttt ttgccatgga
     2041 ttttcagaat cgacatagcc cactactggg aaggaaacgg tgctacttgc acgttctact
     2101 tcaagagctg ggacaaagag gagaggttcc tgatccgcta ggacaaagag gaacatttgg
     2161 cgttcatggg gatcactgta aaaaccagtg aggtaattga ttgtgacggg gtcagatacg
     2221 acagcgacgt ctagtttttc tgattcaaga tatgttagga tttgttgtaa tttagacata
     2281 tgctaccttc tttctacccc tctattttgg caaaaaatga gagaaaatgc aagggagaag
     2341 ggtaaaagaa aagacaaaaa actccgacaa gataacggag ttctttgata tcattttcct
     2401 ttgtttaaga aaagtcagcc ttgcttttga cgtcactgta ctcttcagcg atttcttggc
     2461 tgagaatgtc ctcataggca gggagttgga tgtcctgacc atatttcttc ttgagggcag
     2521 tagtaactag gcgataagcc agattggcat tacgagagag gataggcccg tggaagtagg
     2581 aaccaaagac attcttataa tgaacccctt caccgacctt ttcttcgttg tttccatttc
     2641 catagacaac ctgtcccagc ggtttttggt catcagagag gaaggtacga ccttggtgat
     2701 tttcaaatcc atagtaggtt tcatcgaaat cttcattgtg aatcttgatg tcaccgataa
     2761 aacggttatt ggtctggttg agcgtgtagt gtcccatgac ccctagccct tcgatacgtt
     2821 ttcctgaagc ttcaacataa tattgaccca atagttggaa accaccgcag atagccagaa
     2881 ctacaccgtc gttttggatg tagttgtcaa tgctctcttt tttagcaggt aggtcgtctg
     2941 caatgatact ttgttcaaag tcttgaccac caccgaaaaa ggcgatgtcg tagtgatttt
     3001 catcaaagtc atcatggaga gaaacgatgt caacggtcac atgggttccc agtttttcag
     3061 ccacatactt gagcatgagg atgtttccat tgtccccgta ggtattcatg agatttccgt
     3121 agaggtgggc aatgttgagc tgataggggt aattgccatc ttttgaggaa agtgaagtat
     3181 aaaccattag ttcatctcct ttctaacaat ctgacgacta gccagcagtt cacgaaattc
     3241 cagcatggca gtataagttg ccagaatata ggcatgcttg cagtcttgat tctcaatggt
     3301 cttgagaact tgctccagat tactcgtttc agtgattttc tcagctggat agccagtcac
     3361 tcggaggcga cgagcgattt cagaatgacg aacaccgcca gcgttgattt caggaatgtc
     3421 catgtcagtg atttgctcaa agtctgcatc ccagatccag ctagtgtcaa ttccatctgc
     3481 atagttggca ttaaggagga cagataggct aaatggataa ggtgctagtt tgatcatttc
     3541 gatagcttgg gttgcaccga ctggattttt aatcaagaca agggtacatt ccttgtcacc
     3601 gatatgaaag gtttcttggc gtccaaagac agcacggctc ttgtcaaatc cctgtttgat
     3661 gagttgcgaa tcggcaccta ggaaacgggc gatggccaca gcagctaggg cgttatagat
     3721 attatagagc ccgccgattt ggataccgta ttcttggccg tctatgacaa agcgagagcg
     3781 attgttggtc aactcaacca gttttgtcaa acgatagtcg agatcaggac gtttacatcc
     3841 acaaccctca cagatatagg cacccaagtt tgcataggta ttatgctcat atttgaggat
     3901 gccttggcag tcaggacaga gaatcccttc ggtattgtag tgagccagtt gggctggtcc
     3961 tttttccaag tcaaaaccaa aatactctat agggtttgga atagttggct tgtagaaaag
     4021 tggactgtct ccgttaagga gaacagtagc agttggaact ttccgaatgg catccaatat
     4081 catgttatag gtagtataga tttcaccgaa acggtccatc tggtcacgga agatattagt
     4141 aatgacaaaa agactaggct ggatatagtc acagatacga gatagactgg cttcgtcaat
     4201 ttcgaggacg gcaatatttt tcccagtttt agaagatttg gctgttagga aggttgttgc
     4261 aatccctgta atcatgttgg caccgcttgg gttggttaga acttgaccat aaacctcttt
     4321 taaaatgccg acagtgaggg cagttgtcag ggtttttcca tttgttccag tgacaacgac
     4381 aatctcgtag ttcttagcta ggttttgtaa aatatcttta tcaaattgaa gggcgacttt
     4441 ccctgggagc gtacttccac gtccaagacg gcttaaaacg aagtgggaag aacgcccagc
     4501 aagaaggccc aaagtagttt ttaagttcat gtttctatta tatcacaaaa gagggaaaag
     4561 acagatttgg tgtttcgtag aagtaaaaac agcccaaaga gggctgtcag ttaagatgag
     4621 atttcaactt aaatcgcaaa caagtcattc aagttctcag ccaaggttgg gtgagtgaag
     4681 atttgttttg tgaagtaagt gtaaggaatc ttgttgtcca tagcaacagt aatgatgttg
     4741 atgatttctt gagaaccttc tgagaagatg cttgcaccaa gaatttcttt tgtttcagta
     4801 ttaacaacag ctttgaaagc tccgcgaagg tctccattta cgtgaccacg aggcatggct
     4861 gcaacaggga tttctttcac tgcgtatgga agtttcaaat cagctgcttg gctttcagtc
     4921 aaaccaactt gtgaaagtgc aggtgtgatg aacatagtat ttggtacatt gagacggtcc
     4981 tcaagtgtgt agctgccatc tccagcaagg tagctgtaaa caacacggaa gtcatcaagt
     5041 gaaatgtaag taaattgaag accaccgttg acatctccaa ctgcaaagac accaggaacg
     5101 tttgtttgac agtgtttatc tactttaata gcgccacgtt cagttagttc aatatctgta
     5161 ttttcaagtt gaagtggttc tacatttggt ttgcgtccag ttgcgtagag aagggcgtcg
     5221 aaacggtaag tttcgtcttc agttacgaca agcacttggt caccgtcgtt tttaatttca
     5281 gtagtatgga tattttgaag caattcaata ccgtcttctt ccaggtattg tttagcaaga
     5341 gctgcgatgg aaggttctgc acgaggtagg aatgtatcca aggcatctag gactgtaacc
     5401 ttgcttccta gtttattgta aaggccagca aattcaagac cgatatttcc gccaccaagg
     5461 actccaagtt tttcaggcaa tttatccaag ctttggatac ctgttgagtc aaagacgttt
     5521 ttgcttgtag caagtccagg gattggcaag acgtttgaaa cagcaccagt gttgatgacg
     5581 atagtttcag cagtcaattc ttgtttttca tcaccagctt ggatttcgat gactttattt
     5641 gaaaggaagt gagcttcagc atcaaagata tcgacgccag taccagcaac agtcgtatag
     5701 tttttaccgt tgaggcgacc agtgatcgtg tttttggtag caatgacttc ttcaaaagac
     5761 aagtctttct cagcagcaac cagcaaagtt ttagttggga tacaaccgat gttgatacaa
     5821 gttccaccgt acatagcttt gctacgttca acgagggcaa cttttttgcc agctgaagcc
     5881 aatttacctg ctagtgtttt accagcttta ccaaatccga taacgattaa atcataagtt
     5941 aacatttaga gttcctccta ttcgcatttc attctagcac aagaaaaaaa cttttgcaca
     6001 attctgctac ggaaaagaca gaaaaagata aaaacgcttt ccagacaaaa aactagtaat
     6061 tttttgacaa gcttgataaa ctaaaatcct atctattttt atataagata gaataaatgt
     6121 tcgaaaatag gaggttttat gaaatctaat cgttatatta ttgcctttac tggggtcatt
     6181 ttacacttaa tgctgggttc gacttatgct tggagtgttt atcgtaaccc tattattgaa
     6241 aaaacgggat gggatcaggc ttctgttgcc tttgccttta gtctagcaat cttttgtttg
     6301 ggcttatcgg ctgcatttat ggggcgtttg gtagaaaaat ttggtccgag agtcatgggg
     6361 agtctatctg cttttctata cgcaggtgga aatatcttaa caggatttgc aatagaccgt
     6421 caggaactgt ggttgttgta tctcgcttat ggcattttag gtgggcttgg tttgggagca
     6481 ggctatatta cccctgtgtc aacgattata aaatggtttc ctgataaacg tggtctcgca
     6541 acaggtttag cgattatggg gtttggtttt gcttctttat tgactagtcc catagcgcaa
     6601 catctcatcg caggggtagg gcttgtagaa actttttata ttttaggtgc aagttacttt
     6661 attatcatgc tcctagcttc acaattcatt aagcgtccaa atgagcaaga gcttgcaatt
     6721 ttatctgctt cagggaaaga aaaaacagac tctctgacgc aagggatgac tgcaaatcag
     6781 gctctaaaaa gcaatcggtt ttatatactt tggattattt tctttatcaa catagcttgt
     6841 ggtttaggct taatttcagc ggcatcgcca atggcacagg agatggctgg cttgtctaca
     6901 agtcatgcag cagtaatggt gggcgtttta gggattttca atggatttgg tcgcttgctc
     6961 tgggcgagct tatctgacta tatcggtcgc cctctaacct ttagtatatt actgcttgtt
     7021 aatcttttct tttctctctc actttggctc tttacagatt ccgttttatt tgtagtcgct
     7081 atgtctattt tgatgacttg ctatggagct ggtttttcat tgatcccagc ttatctcagt
     7141 gatatttttg gaaccaagga attggccgct ctgcatggat atattttaac agcttgggca
     7201 atggctggtt tagcgggacc tattttatta gcagagactt ataaaatggc tcattcgtac
     7261 acacaaacct tgttcgtttt tctcatttta tacagtatcg ccttggcttt gtcttattat
     7321 ctaggtcgtt caatcaaaaa agaaagtcaa aaaccgctta catgattttc tgtagaaatg
     7381 gggctatctt ttgctctggt cttgtgttat actagatagg ttgcaaagaa aacagtactt
     7441 ttcttttgtg gaaaagaagc aacacgattt tatatctagt tatatgaaaa tacgtcataa
     7501 aaagaaaagt ataaactaag ccctataggg tggcttcgca ccacctttag aaagaagaat
     7561 aacgtgaaat ttaatgaatt aaacttgtct gctgatttgc tagcagaaat tgaaaaagct
     7621 ggttttgtag aagctagtcc tatccaagaa caaactattc ctttggccct tgaaggcaag
     7681 gatgttatcg gtcaagctca gactggtaca ggaaaaactg cagcctttgg cttgcctacc
     7741 cttgaaaaaa tccgtacaga agaagcgact atccaagctt tggtcatcgc tccaactcgt
     7801 gaactagctg ttcaaagtca agaagaactc ttccgctttg gtcgtagtaa gggagtcaaa
     7861 gtccgttcag tatatggcgg atcaagcatt gaaaaacaaa ttaaggctct taaatctggt
     7921 gcccatatcg tggtgggaac tccaggtcgc ctcttggact tgattaaacg caaggccttg
     7981 aaattacaag acattgaaac ccttatcctt gacgaagcgg atgaaatgct taacatgggc
     8041 ttccttgaag acatcgaagc cattatttcc cgtgtacctg agaaccgtca aactttgctt
     8101 ttctcagcaa ctatgccaga tgccatcaaa cgtatcggtg ttcagtttat gaaagcccct
     8161 gaacatgtca agattgcggc taaggaattg acaacagaat tggttgacca gtactatatc
     8221 cgtgttaagg aacaagaaaa atttgacacc atgactcgtc tcatggatgt ggcacaacca
     8281 gaactcgcta ttgtatttgg tcgtaccaaa cgccgtgtgg atgaattgac tcgtggtttg
     8341 aaaattcgtg gcttccgtgc agaaggaatt catggcgacc tagaccaaaa caaacgtctt
     8401 cgtgtccttc gtgactttaa aaatggcaat cttgatgttt tggttgcgac agacgttgca
     8461 gcgcgtggtt tggatatttc aggtgtgacc catgtctaca actacgatat tccacaagat
     8521 cctgagagtt atgttcaccg tatcggtcgt acaggtcgtg ctggtaagtc aggtcaatct
     8581 attacttttg tttctccaaa cgaaatgggt taccttcaaa tcattgaaaa cttgactaag
     8641 aaacgcatga aaggtctcaa acctgcaagt gtagaagaat ccttccaatc aaaaaaacag
     8701 gtagctctca agaaaatcga acgtgatttt gcagatgaaa ccattcgtgc caactttgag
     8761 aaatttggta aggatgctcg caaattggct gctgagttta ctccagaaga attggcaatg
     8821 tatatcttga gtctgacagt ccaagatcca gatagccttc cagaagtgga gattgcacgt
     8881 gaaaaaccac taccgtttaa accatcaggt aatggtttcg gtggtaaagc taagggaggt
     8941 cgtggaggcc gtcgtgggga cgaccgtcga gagcgtgatc gccgtggcaa tggtcgccgt
     9001 gatgagttca aaaaaggaag tcgtggcaac gatcgttttg ataaggaaaa acgttaccgt
     9061 aaggataata aaaaaccacg caatacttta agcgaaaagc aaacaggctt tgttattcgt
     9121 aacaagggcg gtaaataaga aaaagcggtt caaaatgaat cgctttttta tataaggaga
     9181 ccgaatgtga aaagacaaat aaaattatca tattatcttt tataatgtta tgatacacaa
     9241 aaataggcaa cttgtcaata gaaaaggaac aatttaatta aaaatattct ggtttttaat
     9301 taaattgtaa gtcaatgcaa gtcaataagg aattttcaga taattattga aaaagagacg
     9361 tttttatgtt ataatgatag cgattaaatt cgaggtgaaa aatggcacat ttattagaaa
     9421 aaactagaaa aattacatca attttgaaac gctcagagga gcagttgcag gatgagctcc
     9481 cttacaacgc tattacgcgt cagttagcgg atattattca ttgcaatgcc tgcattatca
     9541 atagtaaggg acgtctgctt ggctatttta tgcgttataa aacaaataca gatcgcgtag
     9601 agcaattctt ccaaactaag attttcccag atgactacgt tcaaggggct aatatgattt
     9661 acgaaacaga agcaaacttg cctgttgagc atgatatgag tattttccct gttgagagta
     9721 gagatgattt tccagatggc ttgacgacta ttgcaccgat tcatgtatcg gggattcgcc
     9781 ttggttcttt gattatttgg cgtaatgata aaaaattcga agatgaggac ttggttcttg
     9841 ttgagattgc cagtaccgtt gttgggattc agcttcttaa cttccaacgt gaagaagatg
     9901 agaaaaatat tcgtcgtcgt actgctgtca ccatggcggt caataccctt tcttactccg
     9961 aactccgtgc tgtttcagca attttagggg aattaaatgg aaatgaaggg aagttgactg
    10021 cgtcagtgat tgcagatcgt atcggaatca ctcgctctgt gattgtcaat gctcttcgta
    10081 aacttgagtc tgcggggatt attgaaagtc gctcacttgg aatgaaggga acctatctta
    10141 aggtcttgat ttcagatatt tttgaagaag tgaagaaaag agattactaa tgacaaaggc
    10201 tttaatttcg attgattata cagaagattt tgttgctgat agtgggaaac taacagcagg
    10261 tgctccagct caggcgattt cggatgccat cagcaaggta actcgattag cttttgaacg
    10321 aggagattat atcttcttta ctattgatgc tcatgaagaa aacgattgtt tccatccgga
    10381 aagtaagtta tttcctcctc ataatctgat tgggacgagt ggacggaatt tatatggaga
    10441 tttggggatc ttttatcaag agcatggttc agacagtcgt gtcttttgga tggataaacg
    10501 ccattactca gctttttcag ggactgacct agatattcgt ttgagagagc gtagagtgtc
    10561 taccgttatc ttaacaggtg tcttgacgga tatctgtgtc ctacatacag ctatagatgc
    10621 ctataatcta ggatatgaca tcgagattgt taaaccagct gttgcttcca tctggcctga
    10681 aaatcatcaa tttgccctag gtcatttcaa aaatacactc ggagctaagt tagtagatga
    10741 aaatctaaat gaactttctg agtaacctgg ttggtgaaaa tgaaaaaatt tgaaaaaaag
    10801 tgttgacaag catcccaaaa gttgatatac tagtaaagta atcgatgcgg ggatggcgga
    10861 attggcagac gcgcaggact aaggatcctg tgaccgcttt aggtcgtgag ggttcaagtc
    10921 cctctctccg cataggaaaa gagttagcta aagctagctc ttttgtattt ctctaaaaaa
    10981 ttagaatcca gtcaaatgta gtggagaatc agcgaaaata tgggaaaact gatccttgtt
    11041 tctgcttttg tctatagaag aataataaag attatcttct tcaaattctc cgatattctc
    11101 taaagttttg tgcaagttgc acagaacttg tttatttttt tggtcatctt gccatagaaa
    11161 tataaagcgt tttcatatat aatataatta ttaaaagaca aaaggagttc acctcatggt
    11221 agaattgaat cttaaaaata tttacaaaaa atatccaaac agcgaacact attcagttga
    11281 agatttcaac ttgaacatca aagataaaga atttatcgtt ttcgtaggac cttcaggatg
    11341 tggtaaatca actacactcc gtatgattgc tggtcttgaa gacattacag aaggtactgc
    11401 atctatcgat ggcgtagttg tcaacgacgt agctccaaaa gaccgtgata tcgccatggt
    11461 attccaaaac tacgctcttt acccacacat gactgtttat gacaacatgg ctttcggttt
    11521 gaaattgcgt aaatacagca aagaagacat taacaaacgt gttcaagaag cagctgaaat
    11581 acttggattg aaagaattct tggaacgtaa accagctgac ctttcaggtg gtcaacgtca
    11641 acgtgttgcc atggggcgtg cgattgtccg tgatgcgaaa gtattcttga tggacgaacc
    11701 tttgtcaaac ttggatgcca aacttcgtgt atcaatgcgt gctgaaatcg ctaaaattca
    11761 ccgtcgtatc ggagctacaa ctatctatgt aactcacgac caaacagaag cgatgacact
    11821 tgcagaccgt atcgttatta tgtcagctac taagaaccct gctggtacag gtactatcgg
    11881 acgtgtagaa caaatcggta ctcctcaaga agtttacaaa aatccagtta acaaattcgt
    11941 tgcaggattc atcggaagcc cagctatgaa cttcatcacc gtgaaattgg ttggtagcga
    12001 aattgtttct gacggtttcc gtttgaaagt gccagaagga gcattgaaag ttcttcgtga
    12061 aaaaggctac gaaggaaaag aattgatctt tggtatccgt ccagaagacg tgaatgcaga
    12121 acctgctttc cttgaaacat tcccagactg tgttgtaaaa gcgactatct ctgtatcaga
    12181 actgcttggt tcagaatctc acctttactg ccaagttggt aaagacgagt ttgttgcaaa
    12241 agttgatgct cgtgactact tgcaaacagg tgcaacagtt gagcttggat ttgacttgaa
    12301 caaagcacac ttcttcgatg tagaaactga aaaaacaatc tactaaaata aataaaattc
    12361 aaagcactac aagaaaagat atctctttat caattgtagt ggagagatat cagttaatct
    12421 agggagagaa acaaaatgct tctctccttt ttgctaggga agtcatatta tgcatctata
    12481 ttgtgatgct ctttaatact cttcgaaaat ctcttcaaac cacgtcaacg tcgccttgcc
    12541 gtacgtatga ttactgattt cgtcagtttt atctgcaacc tcaaagatgt actttgagca
    12601 gcttacggct agtttcctag tttgctcttt gatttccatt gagtattatt tgtgggtacc
    12661 atctacaagt gaagctatat gcgtaaacta cgtgagcaat tgaattcgaa ctagagaggt
    12721 aataataaat ttatgctata gttatggtga cttgtatgct tttgattcta gtttatcaaa
    12781 taatagatta gaattgtcag ataatatcat tttgtgttat aatgaagaaa aaacagaggt
    12841 gttcaaatgt cagaagcagg tcataagttt ttagcaaaat tggggaaaaa acgcttacgt
    12901 ccaggtggaa agcgtgccac agattggtta attgcagaag gaggattttc aaaagaaaag
    12961 agaatactag aggttgcgtg taatagggga actacagcaa ttgagttggc acagcgtttt
    13021 ggttgcaaga taactgctgt tgatatggat gctcaagctt tagaagtggc taaaaaatct
    13081 gctggaacgg caggtgttgc tcatttaatc agttttgaaa gagcaaatgc aatgaaactt
    13141 ccttatcaag atgctagttt tgatattgtt ataaatgaag ctatgctgac tatgcaagcc
    13201 gatcaagcta agaaaaaatg tgtaatggaa tatctaaggg tattaaaacc tggaggtctt
    13261 ctcttgacac atgatgtgct tcttaaggaa gctaaagagt ctatcagaca ggaattatca
    13321 caagcaattc atgtaaatgt aggtccttta actcaagatg gttgggaaca ggtgatgata
    13381 gaatcaggtt attgtgatgt gaaagcattg actggtgaaa tgacattaat gaaattatcg
    13441 ggtatgattt atgacgaagg tttgctagga actttgaaaa tttgtgtaaa tgcttgtaaa
    13501 aaggagaata gaaagcagtt tttaactatg tataaaatgt ttgctaagaa taaacagaaa
    13561 ttgggcttta ttgcgatggc tagttataaa tcgtcaaaac gttagataat tattgaagtt
    13621 aacttttcct tttttctttc ttaaaaaata tgctataata gagagtaaaa aactttgaaa
    13681 gaaagaaaaa gatgaattta aaagattaca ttgcaacaat tgaaaattat ccaaaggaag
    13741 gcattacctt ccgtgatatt agtcctttga tggctgatgg aaatgcttat agctacgctg
    13801 ttcgtgaaat cgttcagtat gctactgaca agaaagtcga catgatcgtg ggacctgaag
    13861 ctcgtggatt tatcgtgggt tgtccagttg cctttgagtt gggaattggt tttgcgcctg
    13921 ttcgtaagcc aggtaaattg ccacgcgaag ttatttctgc tgactatgaa aaagagtacg
    13981 gtgtcgatac cttgactatg cacgcggatg ccattaagcc aggtcaacgt gttcttattg
    14041 tagatgacct tttggcgaca ggtggaactg ttaaggcaac tatcgagatg attgaaaaac
    14101 ttggtggtgt tatggcaggt tgtgccttcc ttgttgaatt ggatgaattg aacggccgtg
    14161 aaaaaattgg tgactacgac tacaaagttc ttatgcatta ttaatgaa
//
LOCUS       DAVKMO010000049        13400 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVKMO010000049 DAVKMO010000000
VERSION     DAVKMO010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.049"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            167..823
                     /locus_tag="VW361_001664"
     CDS             167..823
                     /locus_tag="VW361_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU9744668.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            813..1136
                     /locus_tag="VW361_001665"
     CDS             813..1136
                     /locus_tag="VW361_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU9744669.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1240..2070
                     /locus_tag="VW361_001666"
     CDS             1240..2070
                     /locus_tag="VW361_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9744670.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2224..3078
                     /locus_tag="VW361_001667"
     CDS             2224..3078
                     /locus_tag="VW361_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9744671.1"
                     /translation="MKIKKWLGLVALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3178..4551
                     /locus_tag="VW361_001668"
     CDS             3178..4551
                     /locus_tag="VW361_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU9744672.1"
                     /translation="MVFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4544..5605
                     /locus_tag="VW361_001669"
     CDS             4544..5605
                     /locus_tag="VW361_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU9744673.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5607..6299
                     /locus_tag="VW361_001670"
     CDS             5607..6299
                     /locus_tag="VW361_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9744674.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6328..6897)
                     /locus_tag="VW361_001671"
     CDS             complement(6328..6897)
                     /locus_tag="VW361_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9744675.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPHFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7032..7646
                     /locus_tag="VW361_001672"
     CDS             7032..7646
                     /locus_tag="VW361_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9744676.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7648..9294
                     /locus_tag="VW361_001673"
     CDS             7648..9294
                     /locus_tag="VW361_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9744677.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKLAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9306..10592
                     /locus_tag="VW361_001674"
     CDS             9306..10592
                     /locus_tag="VW361_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9744678.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFAIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVSITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFDQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10644..11177
                     /locus_tag="VW361_001675"
     CDS             10644..11177
                     /locus_tag="VW361_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9744679.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11255..11725
                     /gene="nrdI"
                     /locus_tag="VW361_001676"
     CDS             11255..11725
                     /gene="nrdI"
                     /locus_tag="VW361_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU9744680.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12018..13280)
                     /locus_tag="VW361_001677"
     CDS             complement(12018..13280)
                     /locus_tag="VW361_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU9744681.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3915 a         2510 c         3085 g         3890 t
ORIGIN      
        1 gtgttttgag ctgacttcat cagttctatc tgcaacctca aaacagtgtt ttgagcaacc
       61 tgaggctagt ttcctagttt gctctttgat tttcattgag tattattaag acaatatgag
      121 gagaaagatg aaagaaaaag gattttagga gggggcgcag gcagccatgc caacggctct
      181 tggctatgtc agtatcggcc tggcctgtgg gactatcggt gcgccctatg tgacacctgt
      241 tgagatgggc ttgatgagtc tctttgttta tgctgggagt gcccagtttg ccatgttggc
      301 actgattgtg gttcaagctc ctgtggcagc tattgctatg acggtttttc taatcaactt
      361 gcgtctcttt ttgttgagtt tacacgcatc gacttatttc cgtcatacca gtctttggta
      421 caatatcggt atgtctagta tcttgacaga tgagacctat ggcgttttga tgggtgaatt
      481 ggcccataca gacaaggtaa atcctatgtg gatgcacgga aacaatctta acagctatgt
      541 ggcttggttt gtggggacag tagtcggaac ggctctgggt ggcctgctac caaatccaga
      601 aatctttggc ttggattttg ccctggttgg gatgtttatt ggtatttttg cttcgcaatt
      661 tcagattatg caaagacgga ttcctgtccg caatctgctc attatcctag cagttgttgc
      721 ggtgtccttc tttttgctct tgacagtggt gtctcagtca ctagctgttc tgtttgcgac
      781 gctacttggt tgtagcatgg gggtggtttt agatggtcag taagtatctt ttattagcag
      841 ttattttctc tggcttggtg acttggattc tccgtatgat tcccttcatc ttagtcaagt
      901 ataagggctt gcctgcaatc gttgagcgtt ttttgaagtt cttgcccgtt tccattatct
      961 ttgccttgat tctttcaagc gtagtgacag gtaaggttgg gagccttcct caaattaaat
     1021 ggctagactt cttagccgtc tttccaacag cttgggtagc ctttcgctac cgcaatctag
     1081 tcggaacagt tctctttgga gtggtcttga ttgccatctt gcgtttggtc ttttaaatta
     1141 cccataaaaa aaacttatca cagagataga tatcatataa tggcgtaaat gctctttttc
     1201 tgttaagatt ataaggtatt ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac
     1261 tcatctcttg ctgccctagg acttgttgct gcaggtgtgc ttgcggcttg ctcagggggt
     1321 gctaagaaag aaggagaagc agctagcaag aaagaaatca tcgttgcaac caatggatca
     1381 ccaaggccat ttatctatga agaaaatggc gaattgactg gttacgagat tgaagtcgtt
     1441 cgcgctatct ttaaagattc tgacaaatat gatgtcaagt ttgaaaagac agaatggtca
     1501 ggtgtctttg ctggtcttga cgctgaccgt tacaatatgg ctgtcaacaa tcttagctac
     1561 actaaagaac gtgcggagaa atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc
     1621 cttgtcgtga agaaagatga ctctagtatc aagtctctcg atgatatcgg tggaaaatcg
     1681 acggaagtcg ttcaagccac tacatcagct aagcagttag aagcatacaa cgctgaacac
     1741 acggacaacc caactatcct taactatact aaggcagatt tccaacaaat catggtacgt
     1801 ttgagcgatg gacaatttga ctataagatt tttgataaaa tcggtgttga aacagttatc
     1861 aagaaccaag gtttggacaa cttgaaagtt atcgaacttc caagcgacca acaaccgtac
     1921 gtttacccac ttcttgctca aggtcaagat gagttgaaat catttgtaga caaacgcatt
     1981 aaagaactct acaaagacgg aacgcttgaa aaattgtcta aacaattctt cggagatact
     2041 tatctaccag cagaggctga tattaaataa tttcttgaaa tcatccattc tgagtaagat
     2101 gggtgatttc tcagttttta gggatatagt tttaaactat atatctgatt atctaataac
     2161 aatttgtgaa atcaaacaaa ttgtgagata ctagtacggt attattttta aggagaaaga
     2221 atcatgaaaa tcaaaaaatg gcttggccta gtagcccttg ctacagtcgc aggtttggct
     2281 cttgcagctt gcggaaactc agaaaagaaa gcagacaatg caacaactat caaaatcgca
     2341 actgttaacc gtagcggttc tgaagaaaaa cgttgggaca aaatccaaga attggttaaa
     2401 aaagacggaa ttaccttgga atttacagag ttcacagact actcacaacc aaacaaagca
     2461 actgctgatg gcgaagtaga tttgaacgct ttccaacact ataacttctt gaacaactgg
     2521 aacaaagaaa acggaaaaga ccttgtagcg attgcagata cttacatctc tccaatccgc
     2581 ctttactcag gtttgaatgg aagtgccaac aagtacacta aagtagaaga catcccagca
     2641 aacggagaaa tcgctgtacc gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt
     2701 caatcagctg gcttgattaa attggatgtt tctggaactg ctcttgcaac agttgccaac
     2761 atcaaagaaa atccaaagaa cttgaaaatc actgaattgg acgctagcca aacagctcgt
     2821 tcattgtcat cagttgacgc tgccgttgta aacaatacct tcgttacaga agcaaaattg
     2881 gactacaaga aagcactttt caaagaacaa gctgatgaaa actcaaaaca atggtacaac
     2941 atcattgttg cgaaaaaaga ttgggaaaca tcacctaagg ctgatgctat caagaaagta
     3001 atcgcagctt accacacaga tgacgtgaaa aaagttatcg aagaatcatc agacggtttg
     3061 gatcaaccag tttggtaata agaaacaggg aggtgggaga gagaattcca cctcttgctt
     3121 ttgtatagag cacggagtgt aaagaagact attcgttcat agaaaggtag agagaatatg
     3181 gtttttccta gcgaacaaga acagattgaa aaatttgaaa aggatcatgt agcccagcat
     3241 tattttgagg ttttgcgtac cttgatttct aagaaatcag tctttgccca gcaggttgga
     3301 ctcaaggaag tcgcaaatta tctgggtgag attttcaagc gtgttggagc tgaagtggag
     3361 attgatgaga gctatacagc gccctttgtc atggcacatt tcaagagttc gcgtccagat
     3421 gccaagacct tgattttcta taaccactat gacactgtgc cagcggatgg ggatcaggtc
     3481 tggacagagg atccttttac gctttcggtc cgcaatggct tcatgtatgg gcgtggagtt
     3541 gatgacgaca agggtcatat cacagctcgc ttgagtgctt tgagaaaata tatgcagcac
     3601 catgatgatt tacctgtcaa tatcagcttt atcatggagg gagcggagga atcggcttca
     3661 acagacctag ataagtattt ggaaaagcat gcagacaaac tccgtggggc ggatttgttg
     3721 gtctgggaac aagggaccaa aaatgccttg gaacagctgg aaatttctgg tggcaataag
     3781 gggattgtga cctttgatgc caaggtaaaa agcgctgatg tggatatcca ctcgagttat
     3841 ggtggtgttg tggaatcagc tccttggtat ctcctccaag ccttacagtc tcttcgtgct
     3901 gcggatggcc gtatcttggt tgaaggcttg tacgaagaag tacaagagcc caatgaacga
     3961 gaaatggcct tgctagaaac ttatggtcaa cgaaacccag aggaagttag tcggatttat
     4021 ggattggagt tgcctctctt acaggaggag cggatggcct ttctaaaacg tttctttttc
     4081 gagccagcgc ttaatatcga aggaatccag tctggttatc aaggtcaggg tgttaagact
     4141 attttacctg cagaagccag tgccaagcta gaggttcgtc tggttccggg cctagaaccg
     4201 catgatgttc tggaaaaaat tcggaaacag ctagacaaaa atggctttga taaggtagaa
     4261 ttatactata ccttgggaga gatgagctat cgaagcgata tgagcgcacc agccattctc
     4321 aatgtgatcg agttggccaa gaaattctat ccacagggcg tttcagtctt gccgacgaca
     4381 gcggggacag gacctatgca tacggtcttt gatgccctag aggtaccaat ggttgcattc
     4441 ggtctaggaa atgccaatag ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat
     4501 tattacaccc atatcgaatt agtagaggag ctgattagaa gctatgagta gagatattat
     4561 caagttagat cagatcgatg tgacttttca ccaaaagaag agaaccatta cagcggttaa
     4621 ggatgtgacc attcacatcc aagaagggga tatctacgga atcgttggat attctggagc
     4681 agggaaatca acccttgtac gggtgattaa tctcttgcaa aaaccatctg cagggaaaat
     4741 taccattgac gacgatgtga tttttgacgg caaggtgacc ttgacggcag agcagttgcg
     4801 tcgtaaacgt caagatatcg gaatgatttt ccagcatttt aacctgatga gccaaaagac
     4861 agcagaggag aatgtagcct ttgcccttaa acactctgaa ctcagcaagg aagaaaagaa
     4921 ggctaaagta gctaagttgt tggacttggt tggtttggca gatcgtgctg aaaactaccc
     4981 ttcacaacta tctggagggc aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga
     5041 tccaaaaatc ttgatttcag acgagtcaac ttctgccctt gatccgaaga caaccaagca
     5101 gattttggcc ttgttgcaag atttgaacca aaaattaggc ttgactgttg tcttgattac
     5161 gcatgaaatg cagattgtca aagacattgc caaccgtgtg gcggttatgc aggatgggca
     5221 tttgattgaa gagggtagtg tgcttgaaat cttctcagac cctaaacaac ctttgactca
     5281 agactttatc tcaacagcta caggtattga cgaagccatg gtcaaaatcg agaagcaaga
     5341 aatcgtggaa cacttgtctg aaaacagtct cttggtgcaa ctcaagtacg ctggagcttc
     5401 aacagacgag ccacttttga atgaattgta caagcattac caagtaatgg ctaatattct
     5461 ctatgggaat atcgaaattc tcgatggtac tcctgttgga gaattggtgg tggtcttgtc
     5521 aggtgaaaaa gcagcgttgg caggtgccca agaagccatt cgtcaagcag gtgtacaact
     5581 aaaagtattg aagggagtac agtaagatgg aatcattgat tcaaacctat ttaccaaatg
     5641 tctataaaat gggttgggct ggtcaggcag gctggggaac ggctatctac ttaactcttt
     5701 atatgacagt tctttccttt atcatcggag gcttcttggg gctagtggca ggtcttttcc
     5761 ttgtcttgac agcgccaggt ggtgtcttgg agaataaagt cgtattctgg attttagaca
     5821 aaattacctc aatttttcgt gcggttccct ttatcatcct cttggcaatc ttgtcaccac
     5881 tttctcactt gattgttaaa acaagtatcg ggccaaatgc agcccttgtc ccactttctt
     5941 ttgcagtctt tgccttcttt gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg
     6001 gtgtcattga ggcggctcaa gcgagcggag cgactttctg ggacatcgtg ggtgtttacc
     6061 tatcagaagg tcttccagat ttgatccgtg tgacgactgt gaccttgatt tcccttgttg
     6121 gggaaacagc tatggccggt gcggttggag ctggtggtat cggtaacgta gccatcgctt
     6181 atggatttaa ccgctacaat cacgatgtga ccatcttggc aaccattatt atcattttga
     6241 ttatctttgc aatccaattc ttgggagatt tcttgactaa gaaattgagt cataaataaa
     6301 aagagccgcg tggctctttt taactgatca gattttctgg gcaaattttt tactcaaggc
     6361 ttgtccaatc aaggcaccca ctagggctcc gatgacaata cttgcgataa atagaaggac
     6421 agttccaggg tttggagcga ccatgatacg gtcgatatat tcttgggatt ttcctcttgc
     6481 cagaagagta gccatatagg ctttgggcgc aatccacata agcaagattg gtcctgttgt
     6541 actaaaggcg aaaataatga aagaaaggaa gttctttgtt ttgtccttgt attttcctaa
     6601 atgagctact ccatctgcta ggaggccaca gataattcca ggaaggaagg aaccagcacc
     6661 gtgtttagtt cccaagaaaa agagggcaat gacaaggccg atagtggtaa tggctccaaa
     6721 gtgcggaact tttgcgacta ggatcatata gacgctaccg ccgacaaggg cagtaaaggc
     6781 aggcgcataa aacatgtttc cagtttggtc aaagagattg cccaaaagga caccaatccc
     6841 catgcagagg aagtaaagaa ctgcaaaaag cagtgtagtt aagatagatt tcttcatgaa
     6901 ttgtctcctg ataatttttt cacaattctc attttaccat ggtttggtgg gattgtaaat
     6961 ggatactaga agtttttgaa aacgcttgaa atatgatata atggtttcat agttattttt
     7021 aggggaatat catgggtaga tttttagact ttgtctttaa tcgtttcttt ttagggatga
     7081 ttgcgacagc cttcttttgg ctattaactt tagcaggagg gattatcctt ggtctagcgc
     7141 cggctagtgc caccttgatg agcttatatg cagaacatgg ttatagcttt cgggaataca
     7201 gtttgaagga ggcttggtct ctttacaagc aaaattttgt ctcaagcaac ctgattttct
     7261 atagcttttt aggtgtgggt ctagttttga cctatggttt gtatctcttg gtgcaattgc
     7321 ctcatcagac cattgttcat ttgattgcga cccttttgaa tgtcctagta gttgccctga
     7381 tctttttggc ttatacagta tctttaaaat tacaagttta ttttgccttg tcctatcgaa
     7441 atagtctcaa attatccttg attggcatct ttatgagtct agcagctgtg gccaaggttc
     7501 tccttgggac tgtgctactt gtagcaattg gttactatat gcctgccctg ctattttttg
     7561 taggaattgg gatgtggcat ttctttatca gtgatatgtt ggaacctgtc tatgaaatca
     7621 tccatgaaaa attggcgaca aaatagaatg aagcactttt ggctacatac gcttctaaga
     7681 acctatagtt cagtgatgat cattatcatt gcgagttttg caatcttact ctcttacgct
     7741 gactgggatt cacgtgaaaa ggaagcccag agagtagccc agcgtgtaac tgctagaaca
     7801 gtgagtgaaa ttgaatatta ccatagagag tcaacccaga tagctcaggc tttagttgaa
     7861 aatcaagctc gtattgaggg aatctataaa tactttagcc ttagcatgcc agactatttt
     7921 tactggcaat tagagcggaa agcttcgcct tatatatcag tctctctgta tgaaaatgtt
     7981 gatgacctct atgttcgaaa tgattttgta actggagtgg ccattgcttt tcaagattac
     8041 aaggaagtct atgtttctac taaagacaaa cgtagtggag aaaaaatcag ggctgaggat
     8101 ttcaaactag caggaaatag ttttgccatt ccagtgtcag atccagtgtc agatcaagac
     8161 ttaggagtga tttacatctc cttggatcct gctgttttat accatgccat tgataatact
     8221 agaggtcata ctccgatggc agtaacagtg acctcacctt ttgatacgga gatttttcat
     8281 attggtgaga cagttgataa ggagagtgaa aattggctag ttggcttaac ttctcatggt
     8341 tatcaggttc aggtggcagt tcccaaaaac tttgttttac aaggaacggt gaccagctct
     8401 gctttgattg tgggcttgag ccttctcttt attgtcattc tttatctgac tttgaggcag
     8461 acctttgcta attatcaaaa gcaggtagtg gatttggtgg attccatcca agctattgcc
     8521 caaggacaag aaggtcttcg cattgatacg cttgaaaagg atcaggaatt gctcctaatc
     8581 gcggagacga ccaatgatat gttggatcga ttggaaaaga atatccatga tatttaccag
     8641 ttagaactca gtcaaaaaga tgccaatatg cgggccttgc aggcgcaaat caaccctcac
     8701 ttcatgtata atacgctgga gttcttgcgc atgtacgcag tcatgcagag tcaagatgag
     8761 ttggcagata tcatttatga attcagtagt ctcttgcgta acaatatttc cgacgaaaga
     8821 gagaccctcc tcaaacagga attagaattt tgccgtaaat acagctatct ctgcatggtt
     8881 cgctatccca agtccattgc ctatggtttc aagatagatc cagagttaga gaatatgaag
     8941 attcccaagt ttaccttgca accgctggta gaaaactatt tcgcgcatgg tgttgaccac
     9001 aggcggacag ataatgtgat tagcatcaag gctcttaaac aggatggttt tgtggaaatt
     9061 ttggtggtcg ataatggtag aggaatgtcg gctgaaaagt tggcaaatat ccgagaaaaa
     9121 ttaagtcaga gatattttga acaccaagcc agctacagtg atcaaaggca gtctatcggg
     9181 attgtcaatg tacacgagcg ttttgtgctc tattttggag accgctatgc cattacgata
     9241 gagtctgcag agcaagccgg tgttcagtat cgtattacaa ttcaagatga gtagaaaggg
     9301 agaaaatgta taaagtatta ttagtagatg atgagtacat ggtgacagaa ggtctgaagc
     9361 gtttgattcc ctttgataag tgggatatgg aggtcgtcgc aacagccagt catgccgatg
     9421 aagctctaga atatgttcag gaaaatcctg tcgatgtcat catttccgat gtcaatatgc
     9481 cagacaaaac agggcttgat atgattcggg agatgaaaga gatcttacca gatgctgcct
     9541 atatcctgct ctcaggttat caggagtttg attatgtaaa aagagcaatg aaccttagtg
     9601 tggtggacta tttggtcaag cctgttgata aggtagagct gggaaatctg ctggagaaga
     9661 ttgcaggtca gctcggcgag agagggaaga aaagtcagac tcttagtcaa gaattagacg
     9721 aggctggatt tgttagttat ttaggggata aggagaattg gtggataggt ctatccaagg
     9781 aaaaacaagg ttccttcgcc attccctact atgtcttggg ccaagactgg cagattttca
     9841 tttctgacca acccctagat ggtttagtcg ttacaccttt tgaagctcct tatcaagaac
     9901 actttgaacg ttggaagctg aatgctgaga aaaccctctt ttacggttct gtaaatctgc
     9961 agcagtctga gagtctcttt gcctattacg aaccgattta tagggttatc attcagggaa
    10021 atctcaatca aatcgtagaa gagttaaatc tcttggagaa ggtagttctt gaaaatacac
    10081 ctcgtgtttc gattactaaa cagcttttta tccagtttgt catggatgtt ttccatttat
    10141 ttgaacatct caaagctgat gatatgacgg acattgtcaa aaccattcat gctattcaat
    10201 ccttcgatga attggtttct tatatcaagg aaactctgat cagctttttc gatcaatacc
    10261 gtatgaatga aaatgtggtc agtgtgctgg aagtcattgg tcgtgattac caaaaagagc
    10321 tttccctcaa ggatatcagt aaggccctct ttatcaatcc tgtctatcta gggcagttga
    10381 ttaagcgtga aaccgattcg acctttgcag agttactaaa taaacaacgt attaaggctg
    10441 cccagcagct cttgctttca actagtgaca gcatcgaaga tatttgttat gctgttggtt
    10501 acagtaacct tggatatttc tataaagttt tccgaaaatt gtgcggaaaa tcgccaaaag
    10561 cctaccgaaa acaggtagaa actatactat aagatttgta ttcctttaca aaaggtgcta
    10621 taatattatc aggaggtcct atcatgaaaa agaaaccaat ttatctatgg gttttgctaa
    10681 tcttgtctgc ccttatttca gttccgtctc tgtttggaat tgtgagtccc ttgcctagta
    10741 aagaagccct tcgtgctgct cagaaacaag ttgcaggggt caatgctcag caattagaag
    10801 accagcttaa ttatacctat agagtagcag aagcatctca ttctattttt aatgttgctt
    10861 tgattgtgct atctactatt ttagtggtcg tagcgattgt cttccttgtt cgtaaaaatt
    10921 tgcaatatgc aaactatact tacgttggct atgttttgtt agctattatt ggttcgattt
    10981 atggctatgt tggtttacaa gacgctgtgc agttggttca agatgagagc atgcgtttga
    11041 cagtgagtat tggttcaaaa gctgttagca ttttctatat cgtcatcaat gttctcttcc
    11101 tagcccttgt cttctataag atgtggcgac aacagaaagc cttggcagaa gaagaggaaa
    11161 cagaagagct tacctaagta ttgacaaaaa agaactatca agatacaatc ttggtagttg
    11221 ttttttgatt atagataaaa tcatggaggt acatatgaag acaatttctt tagtttatat
    11281 tagtttgagt ggcaacactg aaagttttgt gacgcgcttg aaagactatc tcttgtccca
    11341 atacaaaggg attgaggttc aaaagattca tatcaaggat ttggtcaagg aaggcaaaaa
    11401 tttctatgaa atggaccatc cctatgtcgc ttttttgccg acctatctcg aaggtgggaa
    11461 tggcgtggat aacggagatg ttgagatttt gacgacaccg gtgggagatt ttattgccta
    11521 tggtaacaat gctagtaagt gttttggtgt ggttgggtca ggaaatcgta actttaataa
    11581 ccaatactgc ctaacagcca agcaatacag tcaacgcttt ggcttccctg tattggctga
    11641 ctttgaaatg cgaggcatgc tggaagatat caaacatgtc gcagctatta tcgcagattt
    11701 gtatgagttg gaaaaggaga attaatactc aatgaaaatc aaagagcaaa ctaggaagct
    11761 agtcgcaggt tgctcaaagc acagctttga ggttgcagat agagctgacg tggtttgaag
    11821 agattctcga atagtataaa gttcttataa gaggtggttg aagttgttca actgtttttt
    11881 gagtataaac agtctttaag aacgtaaaaa agcataagtt caggtcttca aaaccttgtt
    11941 cttatgcttt ttatcataga aatatttgct gaattttctc ttgaaatgaa accttatctt
    12001 catctcgcgc ttgtccctta ccctgctttt ccgattgcga gtgcgtagat aaagaagatg
    12061 gcgaagccaa agaggaaaat caatcccgca atggcaaggt gtttgagcca agaaggaaga
    12121 tttttgtttt cacgcgttac caaggcgtaa ttcaaaagag caaagaaagg tgttgtcagg
    12181 aaagagccaa tcatggcaaa gcggagcatg gttgaaacct gaccagcgaa gaacttgata
    12241 atgacgatac cgatgatagc agtgatggtc atccagatgt tcaaagattt acgattgtcc
    12301 tctttttgac tgattagcag tcggagagat tcctgattaa cgcgagaata gccatcgata
    12361 acagttataa ctgttccaaa gatacagagg aaggcaataa aggtaatcaa gtaacgggac
    12421 cattcgccaa gaacagaggc atacatgccc acgaattgag agatgtattt ggctgaagca
    12481 gcttcaaccg cctgccctgt aggatactga atcagtgctc ccagtgccac aaagaagacg
    12541 gctaggatag ctgttccaat ataaccagtg ttaaagtcaa acagagcgtc ttctgtgtta
    12601 aagttgacgg tctttctctt ttcagctgac caaagtgaat tgatggctga aatttcaata
    12661 ggagccggca tccatcctag gagggagacg atgaagggca gagctgccat ttgccaaggt
    12721 gtcttctcga caaaatcaga actgtattct ggatgcttga ccgccgcaat gataactgca
    12781 agaacagtcg caatggttaa ggcagacata atccatttga ccatgccgtc taaaagtttg
    12841 tagcctccaa agagtagcat agcccaaatg attgcaacga gaatgaggga ccactgagta
    12901 atgctaagtc caatcattgg gaaagcactg gcgatgatag ctgagcacag aatggcaaca
    12961 ccagccgtgt tgaccatagc cgaaaagaca ttgaggataa agaaaatcca gagatagagt
    13021 tttccttttt cggcataacc ttcaaccaaa gtctttccag tatcagctgt gtattcagca
    13081 ccaaaacgga aaaatggata tttaaagaca ttggctaaga tgaccaagag aagtagagac
    13141 caaccgtaag aaccgccagc ttgagttgag gatacaatgt gggaacctcc aacagcggca
    13201 gttgccatta ggattccagg tcccattgct tttagcttgc ttgcccaggt tgattgattt
    13261 aaggaaatag cttgcgacat gataaatact cctttttgaa ttttcagaat aatctgtata
    13321 tgtaatctat attctacaaa aaattttgga aaaatgcaag aatattttga aaaaagatag
    13381 aaaatttaca aagaaaatct
//
LOCUS       DAVKMO010000050        13149 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVKMO010000050 DAVKMO010000000
VERSION     DAVKMO010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13149
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.050"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..1067
                     /gene="dnaN"
                     /locus_tag="VW361_001678"
     CDS             <1..1067
                     /gene="dnaN"
                     /locus_tag="VW361_001678"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU9744682.1"
                     /translation="KNAIPILSTVKIDVTNEGITLIGSNGQISIENFISQKNEDAGLL
                     ITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYPRI
                     QEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSHR
                     LSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIEAVEIFFANNQILFRSENISFYT
                     RLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVS
                     AHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFT
                     LVPADTDEDFMQLITPVRTN"
     gene            1132..1326
                     /locus_tag="VW361_001679"
     CDS             1132..1326
                     /locus_tag="VW361_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU9744683.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            1410..2525
                     /gene="ychF"
                     /locus_tag="VW361_001680"
     CDS             1410..2525
                     /gene="ychF"
                     /locus_tag="VW361_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU9744684.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            2596..3165
                     /locus_tag="VW361_001681"
     CDS             2596..3165
                     /locus_tag="VW361_001681"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU9744685.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            3166..6675
                     /gene="mfd"
                     /locus_tag="VW361_001682"
     CDS             3166..6675
                     /gene="mfd"
                     /locus_tag="VW361_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU9744686.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTKVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            6733..6999
                     /locus_tag="VW361_001683"
     CDS             6733..6999
                     /locus_tag="VW361_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU9744687.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            6992..7360
                     /locus_tag="VW361_001684"
     CDS             6992..7360
                     /locus_tag="VW361_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU9744688.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            7480..8748
                     /locus_tag="VW361_001685"
     CDS             7480..8748
                     /locus_tag="VW361_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU9744689.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            8745..10022
                     /gene="tilS"
                     /locus_tag="VW361_001686"
     CDS             8745..10022
                     /gene="tilS"
                     /locus_tag="VW361_001686"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU9744690.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            10026..10568
                     /gene="hpt"
                     /locus_tag="VW361_001687"
     CDS             10026..10568
                     /gene="hpt"
                     /locus_tag="VW361_001687"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU9744691.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            10584..12542
                     /gene="ftsH"
                     /locus_tag="VW361_001688"
     CDS             10584..12542
                     /gene="ftsH"
                     /locus_tag="VW361_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU9744692.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            12664..13143
                     /locus_tag="VW361_001689"
     CDS             12664..13143
                     /locus_tag="VW361_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU9744693.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLADDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT         4528 a         1974 c         2707 g         3940 t
ORIGIN      
        1 ctaaaaatgc cattcctatt ttatcaacag taaaaattga cgtgaccaat gaaggtatta
       61 ctttaattgg ttcaaatggt caaatttcaa ttgaaaattt tatttctcaa aaaaatgaag
      121 atgctggttt gttaattact tctttaggtt cgatccttct tgaagcttct ttctttatca
      181 atgtagtatc tagtttacct gatgtaactc ttgattttaa agaaattgaa caaaatcaaa
      241 ttgttttaac cagtggcaaa tcagaaatta ccctaaaagg aaaagatagc gaacaatatc
      301 cacgaatcca agaaatttca gcaagcactc ctttaatact tgaaacaaaa ttactcaaga
      361 aaattattaa tgaaacagcc tttgctgcaa gtacacaaga gagtcgtccg attttaacag
      421 gtgtccactt cgtattgagt caacacaaag agttaaaaac agttgcaaca gactctcatc
      481 gcctaagcca gaaaaaattg actcttgaaa aaaatagtga tgattttgat gtcgtaattc
      541 ctagccgttc tctacgcgaa ttttcagcgg tatttacaga tgatatcgaa gctgtagaga
      601 ttttctttgc caataaccaa atcctcttta gaagcgaaaa tattagcttc tatactcgtc
      661 tcctagaagg aaactatcct gatacagatc gcttgattcc aacagacttt aacactacta
      721 ttacttttaa tgtggtaaac ttacgccagt caatggagcg tgcccgtctt ttatcaagtg
      781 cgactcaaaa tggtactgtg aaacttgaaa ttaaggatgg ggttgttagc gcccatgttc
      841 actctccaga agttggtaaa gtaaacgaag aaatcgatac tgatcaggtt actggtgaag
      901 atttgaccat tagtttcaac ccaacttact tgattgattc tcttaaagct ttaaatagcg
      961 aaaaggtgac cattagcttt atctcagctg ttcgtccatt tactcttgtg ccagcagata
     1021 ctgacgaaga cttcatgcag ctcattacac cagttcgtac aaattaagtg aaagaggttg
     1081 agcctggctc gcctctttta tgatataatc gaaaaagaaa aggagagtag tatgtatcaa
     1141 gttggaaatt ttgttgagat gaaaaaatca cacgcttgta caatcaagtc gactggtaaa
     1201 aaggctaatc gttgggaaat tacacgtgta ggagcagata tcaaaataaa atgcagtaat
     1261 tgtgagcatg ttgtcatgat ggggcgatat gattttgagc gaaaaatgaa taaaattatt
     1321 gactgagaac ccttagttag agggttagca ctttatccct ttttgtgtta taatattagg
     1381 gattgaaatg aaaacggaga atgagaaata tggctttgac agcaggtatc gttggtttgc
     1441 caaacgttgg taaatcaaca ctatttaatg caattacaaa agcaggagca gaggcagcaa
     1501 actacccatt tgcgactatt gatccaaatg ttggaatggt ggaagttcca gatgaacgcc
     1561 tacaaaaact aactgaaatg ataactccta aaaagacagt tcccacaaca tttgaattta
     1621 cagatattgc agggattgta aaaggagctt caaaaggaga agggctaggg aataaattct
     1681 tggccaatat tcgtgaagta gatgcgattg ttcacgtagt tcgtgctttt gatgatgaaa
     1741 atgtaatgcg cgagcaagga cgtgaagacg cctttgtaga tccacttgca gatattgata
     1801 caattaatct ggaattaatt cttgctgact tagaatcagt gaacaaacga tatgcgcgtg
     1861 tagaaaagat ggcacgtacg caaaaagata aagaatcagt agcagaattc aatgttcttc
     1921 aaaagattaa accagtccta gaagacggga aatcagctcg taccattgaa tttacagatg
     1981 aggaacaaaa ggttgtcaaa ggtcttttcc ttttgacgac taaaccagtt ctttatgtag
     2041 ctaatgtgga cgaggatgtg gtttcagaac ctgactctat cgactatgtc aaacaaattc
     2101 gtgaatttgc agcgacagaa aatgctgaag tagtcgttat ttctgcgcgt gctgaggaag
     2161 aaatttctga attggatgat gaagataaaa aagagtttct tgaagccatt ggtttgacag
     2221 aatcaggtgt agataagttg acgcgtgcag cttaccactt gcttggattg ggaacttact
     2281 tcacagctgg tgaaaaagaa gttcgcgctt ggactttcaa acgtggtatg aaggctcctc
     2341 aagcagctgg tattatccac tcagactttg aaaaaggctt tattcgtgca gtaaccatgt
     2401 catatgaaga tctagtgaaa tacggatctg aaaaggccgt aaaagaagct ggacgcttgc
     2461 gtgaagaagg aaaagaatat atcgttcaag atggcgatat catggaattc cgctttaatg
     2521 tctaaaaatt aataaatggt gtcaattagg ttggaaaaaa attccaaccc ttttggcttt
     2581 tgaaaggaaa aataaatgac caaattactt gtaggcttgg gaaatccagg ggataaatat
     2641 tttgaaacaa aacacaatgt tggttttatg ttgattgatc aactagcgaa gaaacagaat
     2701 gtcactttta cacacgataa gatatttcaa gctgacctag catccttttt cctaaatgga
     2761 gaaaaaattt atctggttaa accaacgacc tttatgaatg aaagtggaaa agcagttcat
     2821 gctttattaa cttactatgg tttggatatt gacgatttac ttatcattta cgatgatctt
     2881 gacatggaag ttgggaaaat tcgtttaaga gcaaaaggct cagcaggtgg tcataatggt
     2941 atcaagtcta ttattcaaca tataggaact caggtcttta accgtgttaa gattggaatt
     3001 ggaagaccta aaaatggtat gtcagttgtt catcatgttt tgagtaagtt tgacagggat
     3061 gattatatcg gtattttaca gtctgttgac aaagttgacg attctgtaaa ctactattta
     3121 caagagaaaa attttgagaa aacaatgcag aggtataacg gataaatggt gaccttatta
     3181 gatttattct cagaaaatga tcagattaaa aaatggcatc aaaatttaac agataagaaa
     3241 agacaactaa tacttggttt atcaacatct actaaggcgc ttgcaattgc aagcagttta
     3301 gaaaaagaag ataggattgt gttattgacg tcaacttatg gagaagcaga aggacttgtt
     3361 agtgatctta tatctatctt gggtgaggaa ctcgtctatc catttttggt agatgatgct
     3421 cctatggtgg agtttttgat gtcttcacag gaaaaaatta tttcacgggt tgaagccttg
     3481 cgttttttga ctgattcatc taagaaaggg attttagttt gtaatatcgc agcaagtcga
     3541 ttgattttac cgtctcccaa tgcattcaaa gatagtattg taaaaatctc agttggtgaa
     3601 gaatatgatc aacacgcgtt tatccatcag ttaaaggaaa atggctatcg aaaagttact
     3661 aaagtacaaa ctcagggcga atttagtctt cgaggagata ttttagatat ttttgaaata
     3721 tcccagttag aaccttgtcg aattgagttt tttggtgatg aaattgatgg tatcaggtca
     3781 tttgaagtag aaacacaatt atcgaaagaa aataagacag aactcactat ctttccagct
     3841 agtgatatgc ttttgagaga aaaggattat caacgaggac agtcagcttt agaaaaacaa
     3901 atttcaaaaa ctttatcacc tattttgaaa tcatacctag aagaaattct ttcaagtttt
     3961 caccaaaaac aaagtcatgc agactctcgg aagtttttat ctttgtgcta tgataagaca
     4021 tggactgtct ttgattatat tgaaaaagat actccaatat tctttgatga ttatcaaaaa
     4081 ttgatgaatc agtatgaagt ctttgaaaga gacttagcgc agtactttac agaagaatta
     4141 cagaatagta aagcattttc tgatatgcag tatttttctg atattgaaca aatctataaa
     4201 aaacaaagtc cagtgacctt tttctctaat cttcaaaagg gtttaggaaa tctcaaattt
     4261 gacaaaattt atcaattcaa tcaatatcct atgcaggaat ttttcaatca gttttctttt
     4321 ctaaaagaag aaattgaacg atataaaaaa atggattaca ccattattct gcagtctagc
     4381 aattcaatgg gaagtaaaac attggaggat atgttagagg aatatcagat taaattggat
     4441 tctagagata agacaagtat ctgtaaagaa tctgtaaact taatagaggg taatctcaga
     4501 catggttttc attttgtaga tgaaaagatt ttattgataa ctgaacatga gatttttcaa
     4561 aagaaattaa agcgtcgttt tcgaagacaa catgtttcaa atgcagagag attaaaagat
     4621 tacaatgaac ttgaaaaagg ggactatgtt gtccatcata tccatgggat tggtcaatat
     4681 ctaggaattg aaaccattga aatcaaggga attcatcgcg attatgtcag tgtccaatac
     4741 caaaatggtg atcaaatttc tatccccgtg gaacagattc atctactgtc caaatatatt
     4801 tcaagtgatg gtaaagctcc aaaactcaat aaattaaatg acggtcattt taaaaaggcc
     4861 aagcaaaagg ttaagaacca ggtagaggat atagctgatg atttaatcaa actctactct
     4921 gaacgtagtc agttgaaggg ttttgctttc tcagctgatg atgatgatca agatgccttt
     4981 gatgatgctt tcccttatgt tgaaacggat gatcaacttc gtagtattga ggaaatcaag
     5041 agggatatgc aggcttctca gccaatggat cgacttttag ttggggatgt tggttttgga
     5101 aagactgaag ttgctatgcg tgcagccttt aaagcagtca atgatcacaa acaggttgtc
     5161 attctagttc cgacgacggt tttagcgcaa cagcactata cgaattttaa ggaacgattc
     5221 caaaattttg cagttaatgt tgatgtgttg agtcgcttta gaagtaaaaa agagcagact
     5281 gcaacacttg aaaaattgaa aaacggtcaa gtcgatattt tgattggaac acatcgtgtt
     5341 ttgtcaaaag atgttgtgtt tgctgatttg ggcttgatga ttattgatga ggaacagcga
     5401 tttggtgtca agcataagga aactttgaaa gaactgaaga aacaagtgga tgtcctaacc
     5461 ttgaccgcta cgccaatccc tcgtaccctc catatgtcta tgctgggaat cagagatttg
     5521 tctgttattg aaactccgcc gactaatcgc tatcctgttc agacctatgt tttggaaaag
     5581 aatgatagtg tcattcgtga tgctgtcttg cgtgaaatgg agcgtggagg tcaagtttac
     5641 tatctttaca acaaagttga tacaattgtt cagaaggttt cagaattaca ggagttgatt
     5701 ccggaggctt cgattggata tgttcatggt cgaatgagtg aagtccagtt ggaaaatact
     5761 ctattagact ttattgaggg acaatacgat atcttggtga cgactactat tattgagaca
     5821 ggggtggaca ttccaaatgc taatacttta tttattgaaa atgcggacca tatgggcttg
     5881 tcaaccttat atcagttaag aggaagagtc ggtcgtagta atcgtattgc ttatgcttat
     5941 ctcatgtatc gtccagaaaa atcaatcagt gaagtctctg aaaagagatt agaagcgatt
     6001 aaaggattta cagaattggg ctctggcttt aagattgcaa tgcgagatct ttcgattcgt
     6061 ggagcaggaa atcttttagg aaaatcccag tctggtttca ttgattctgt tggttttgaa
     6121 ttgtattcgc agttattaga ggaagctatt gctaaacgaa acggtaatgc taacgctaac
     6181 acaagaacca aagggaatgc tgagttgatt ttgcaaattg atgcctatct tcctgatact
     6241 tatatttctg atcaacgaca taagattgaa atttacaaga aaattcgtca aattgacaac
     6301 cgtgtcaatt atgaagagtt acaagaggag ttgatagacc gttttggaga atacccagat
     6361 gtagtagcct atcttttaga gattggtttg gttaaatcat acttggacaa ggtctttgtt
     6421 caacgtgtgg aaagaaaaga taataaaatt acaattcaat ttgaaaaagt cactcaacga
     6481 ctgtttttag ctcaagatta ttttaaagct ttatccgtaa cgaacttaaa agcaggcatc
     6541 gctgagaata agggattaat ggagcttgta tttgatgtcc aaaataagaa agattatgaa
     6601 attttagaag gtttgctgat ttttggagaa agtttattag agataaaaga gtctaaggaa
     6661 gaaaattcca tttgatattt ttcttctata aaatagataa aaatggtaca ataataaatt
     6721 gaggtaataa ggatgagatt agataaatat ttaaaagtat cgcgaattat caagcgtcgt
     6781 acagtcgcaa aggaagtagc agataaaggt agaatcaagg ttaatggaat cttggccaaa
     6841 agttcaacgg acttgaaagt taatgaccaa gttgaaattc gctttggcaa taagttgctg
     6901 cttgtaaaag tactagagat gaaagatagt acaaaaaaag aagatgcagc aggaatgtat
     6961 gaaattatca gtgaaacacg ggtagaagaa aatgtctaaa aatattgtac aattgaataa
     7021 ttcttttatt caaaatgaat accaacgtcg tcgctacctg atgaaagaac gacaaaaacg
     7081 gaatcgtttt atgggagggg tattgatttt gattatgcta ttatttatct tgccaacttt
     7141 taatttagcg cagagttatc agcaattact ccaaagacgt cagcaattag cagacttgca
     7201 aactcagtat caaactttga gtgatgaaaa ggataaggag acagcatttg ctaccaagtt
     7261 gaaagatgaa gattatgctg ctaaatatac acgagcgaag tactattatt ctaagtcgag
     7321 ggaaaaagtt tatacgattc ctgacttgct tcaaaggtga taaaatggaa aatttattag
     7381 acgtaataga gcaatttttg agtttgtcag atgaaaagct ggaagaattg gctgataaaa
     7441 atcaattatt gcgtttacaa gaagaaaagg aaaggaagaa tgcgtaaatt cttaattatt
     7501 ttgttgctac caagtttttt gaccatttca aaagtcgtta gcacagaaaa agaagtagtc
     7561 tatacttcga aagaaattta ttacctttca caatctgact ttggtattta ttttagagaa
     7621 aaattaagtt ctcccatggt ttatggagag gttcctgttt atgcgaatga agatttagta
     7681 gtggaatctg ggaaattgac tcccaaaaca agttttcaaa taaccgagtg gcgcttaaat
     7741 aaacaaggaa ttccagtatt taagctatca aatcatcaat ttatagctgc ggacaaacga
     7801 tttttatatg atcaatcaga ggtaactcca acaataaaaa aagtatggtt agaatctgac
     7861 tttaaactgt acaatagtcc ttatgattta aaagaagtga aatcatcctt atcagcttat
     7921 tcgcaagtat caatcgacaa gaccatgttt gtagaaggaa gagaatttct acatattgat
     7981 caggctggat gggtagctaa agaatcaact tctgaagaag ataatcggat gagtaaagtt
     8041 caagaaatgt tatctgaaaa atatcagaaa gattctttct ctatttatgt taagcaactg
     8101 actactggaa aagaagctgg tatcaatcaa gatgaaaaga tgtatgcagc cagcgttttg
     8161 aaactctctt atctctatta tacgcaagaa aaaataaatg agggtcttta tcagttagat
     8221 acgactgtaa aatacgtatc tgcagtcaat gattttccag gttcttataa accagaggga
     8281 agtggtagtc ttcctaaaaa agaagataat aaagaatatt ctttaaagga tttaattacg
     8341 aaagtatcaa aagaatctga taatgtagct cataatctat tgggatatta catttcaaac
     8401 caatctgatg ccacattcaa atccaagatg tctgccatta tgggagatga ttgggatcca
     8461 aaagaaaaat tgatttcttc taagatggcc gggaagttta tggaagctat ttataatcaa
     8521 aatggatttg tgctagagtc tttgactaaa acagattttg atagtcagcg aattgccaaa
     8581 ggtgtttctg ttaaagtagc tcataaaatt ggagatgcgg atgaatttaa gcatgatacg
     8641 ggtgttgtct atgcagattc tccatttatt ctttctattt tcactaagaa ttctgattat
     8701 gatacgattt ctaagatagc caaggatgtt tatgaggttc taaaatgagg gaaccagatt
     8761 ttttaaatca ttttctcaag aagggatatt tcaaaaagca tgctaaggcg gttctagctc
     8821 tttctggtgg attagattct atgtttctat ttaaggtatt gtctacttat caaaaagagt
     8881 tagagattga attgattctg gctcatgtga atcataagca gagaattgaa tcagattggg
     8941 aagaaaagga attaaggaag ttggctgctg aagcagagct tcctatttat atcagcaatt
     9001 tttcaggaga attttcagaa gcgcgtgcac gaaattttcg ttatgatttt tttcaagagg
     9061 ttatgaaaaa gacaggtgcg acagctttag tcactgccca ccatgctgat gatcaggtgg
     9121 aaacgatttt gatgcgcttg attcgaggaa ctcgcttgcg ctatctatca ggaattaagg
     9181 agaagcaagt agtcggagag atagaaatca ttcgtccctt cttgcatttt cagaaaaaag
     9241 actttccatc aatttttcac tttgaagata catcaaatca ggagaatcat tattttcgaa
     9301 atcgtattcg aaactcttac ttaccagaat tggaaaaaga aaatcctcga tttagggatg
     9361 caatcttagg cattggcaat gaaattttag attatgattt ggcaatagct gaattatcta
     9421 acaatattaa tgtggaagat ttacagcagt tattttctta ctctgagtct acacaaagag
     9481 ttttacttca aacttatctg aatcgttttc cagatttgaa tcttacaaaa gctcagtttg
     9541 ctgaagttca gcagatttta aaatctaaaa gccagtatcg tcatccgatt aaaaatggct
     9601 atgaattgat aaaagagtac caacagtttc agatttgtaa aatcagtccg caggctgatg
     9661 aaaaggaaga tgaacttgtg ttacactatc aaaatcaggt agcttatcaa ggatatttat
     9721 tttcctttgg acttccatta gaaggtgaat taattcaaca aatacctgtt tcacgtgaaa
     9781 catccataca cattcgtcat cgaaaaacag gagatgtttt gattcaaaat gggcatagaa
     9841 aaaaactcag acgtttattt attgatttga aaatccctat ggaaaagaga aactctgctc
     9901 ttattattga gcaatttggt gaaattgtct caattttggg aattgcgacc aataatttga
     9961 gtaaaaaaac gaaaaatgat ataatgaaca ctgtacttta tatagaaaaa atagataggt
    10021 aaaaaatgtt agaaaacgat attaaaaaag tcctcgtttc acacgatgaa attacagaag
    10081 cagctaaaaa actaggtgct caattaacta aagactatgc aggaaaaaat ccaatcttag
    10141 ttgggatttt aaaaggatct attcctttta tggctgaatt ggtcaaacat attgatacac
    10201 atattgaaat ggacttcatg atggtttcta gctaccatgg tggaacagca agtagtggtg
    10261 ttatcaatat taaacaagat gtgactcaag atatcaaagg aagacatgtt ctatttgtag
    10321 aagatatcat tgatacaggt caaactttga agaatttgcg agatatgttt aaagaaagag
    10381 aagcagcttc tgttaaaatt gcaaccttgt tggataaacc agaaggacgt gttgtagaaa
    10441 ttgaggcaga ctatacctgc tttactatcc caaatgagtt tgtagtaggt tatggtttag
    10501 actacaaaga aaattatcgt aatcttcctt atattggagt attgaaagag gaagtgtatt
    10561 caaattagaa agaataatct ttaatgaaaa aacaaaataa tggtttaatt aaaaatcctt
    10621 ttctatggtt attatttatc tttttccttg tgacaggatt ccagtatttc tattctggga
    10681 ataactcagg aggaagtcag caaatcaact atactgagtt ggtacaagaa attaccgatg
    10741 gtaatgtaaa agaattaact taccaaccaa atggtagtgt tatcgaagtt tctggtgtct
    10801 ataaaaatcc taaaacaagt aaagaaggaa caggtattca gtttttcacg ccatctgtta
    10861 ctaaggtaga gaaatttacc agcactattc ttcctgcaga tactaccgta tcagaattgc
    10921 aaaaacttgc tactgaccat aaagcagaag taactgttaa gcatgaaagt tcaagtggta
    10981 tatggattaa tctactcgta tccattgtgc catttggaat tctattcttc ttcctattct
    11041 ctatgatggg aaatatggga ggaggcaatg gccgtaatcc aatgagtttt ggacgtagta
    11101 aggctaaagc agcaaataaa gaagatatta aagtaagatt ttcagatgtt gctggagctg
    11161 aggaagaaaa acaagaacta gttgaagttg ttgagttctt aaaagatcca aaacgattca
    11221 caaaacttgg agcccgtatt ccagcaggtg ttcttttgga gggacctccg gggacaggta
    11281 aaactttgct tgctaaggca gtcgctggag aagcaggtgt tccattcttt agtatctcag
    11341 gttctgactt tgtagaaatg tttgtcggag ttggagctag tcgtgttcgc tctctttttg
    11401 aggatgccaa aaaagcagca ccagctatca tctttatcga tgaaattgat gctgttggac
    11461 gtcaacgtgg agtcggtctc ggcggaggta atgacgaacg tgaacaaacc ttgaaccaac
    11521 ttttgattga gatggatggt tttgagggaa atgaagggat tatcgtcatc gctgcgacaa
    11581 accgttcaga tgtacttgat cctgcccttt tgcgtccagg acgttttgat agaaaagtat
    11641 tggttggccg tcctgatgtt aaaggtcgtg aagcaatctt gaaagttcac gctaagaaca
    11701 agcctttagc agaagatgtt gatttgaaat tagtggctca acaaactcca ggctttgttg
    11761 gtgctgattt agagaatgtc ttgaatgaag cagctttagt tgctgctcgt cgcaataaat
    11821 cgataattga tgcttcagat attgatgaag cagaagatag agttattgct ggaccttcta
    11881 agaaagataa gacagtttca caaaaagaac gagaattggt tgcttaccat gaggcaggac
    11941 ataccattgt tggtctagtc ttgtcgaatg ctcgcgttgt ccataaggtt acaattgtac
    12001 cacgcggccg tgcaggcgga tacatgattg cacttcctaa agaggatcaa atgcttctat
    12061 ctaaagaaga tatgaaagag caattggctg gcttaatggg tggacgtgta gctgaagaaa
    12121 ttatctttaa tgtccaaact acaggagctt caaacgactt tgaacaagcg acacaaatgg
    12181 cgcgtgcaat ggttacagag tacggtatga gtgaaaaact tggcccagta caatatgaag
    12241 gaaaccatgc tatgtttggt gcacagagtc ctcaaaaatc aatttcagaa caaacagctt
    12301 atgaaattga tgaagaggtt cgttcattat taaatgaggc acgaaataaa gctgctgaaa
    12361 ttattcagtc aaatcgtgaa actcacaagt taattgcaga agcattattg aaatacgaaa
    12421 cattggatag tacacaaatt aaagctcttt acgaaacagg aaagatgcct gaagcagtag
    12481 aagaggaatc tcatgcacta tcctatgatg aagtaaagtc aaaaatgaat gacgaaaaat
    12541 aaccctgaga gaggctggag cctctctttt ttgtgcagtt taggagctaa agggaacaga
    12601 atggataaaa tggaacaaat gtgttttcta atctgttaga ctgtatctag aaaggggaaa
    12661 attatgatta aagaattgta tgaagaagtc caagggactg tgtataagtg tagaaatgaa
    12721 tattaccttc atttatggga attgtcggat tgggaccaag aaggcatgct ctgcttacat
    12781 gaattgatta gtagagaaga aggactggca gacgatattc cacgtttaag gaaatatttc
    12841 aaaaccaagt ttcgaaatcg aattttagac tatatccgta agcaggaaag tcagaagcgt
    12901 agatacgata aagaacccta tgaagaagtg ggtgagctca gtcatcgtat aagtgaggga
    12961 ggtctctggc tagatgatta ttatctcttt catgaaacac taagagatta tagaaacaaa
    13021 caaagtaaag agaaacaaga agaactagaa cgcgtcttaa gcaatgaacg atttcgaggg
    13081 cgtcaaagag tattaagaga cttacgcatt gtgtttaagg agtttactat ccgtacccac
    13141 tagtaagtc
//
LOCUS       DAVKMO010000051        12872 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVKMO010000051 DAVKMO010000000
VERSION     DAVKMO010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12872
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.051"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..222
                     /locus_tag="VW361_001690"
     CDS             <1..222
                     /locus_tag="VW361_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744694.1"
                     /translation="VNGSWYYLNANGSMATGWVKDGDTWYYLEASGAMKASQWFKVSD
                     KWYYVNGLGALAVNTTVDGYKVNANGEWV"
     gene            623..1744
                     /gene="mnmA"
                     /locus_tag="VW361_001691"
     CDS             623..1744
                     /gene="mnmA"
                     /locus_tag="VW361_001691"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU9744695.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFT
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1885..2340
                     /locus_tag="VW361_001692"
     CDS             1885..2340
                     /locus_tag="VW361_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9744696.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNRKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2350..4263
                     /gene="mnmG"
                     /locus_tag="VW361_001693"
     CDS             2350..4263
                     /gene="mnmG"
                     /locus_tag="VW361_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU9744697.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(4642..6321)
                     /locus_tag="VW361_001694"
     CDS             complement(4642..6321)
                     /locus_tag="VW361_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9744698.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6323..6556)
                     /locus_tag="VW361_001695"
     CDS             complement(6323..6556)
                     /locus_tag="VW361_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU9744699.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDTSSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6836..7051
                     /locus_tag="VW361_001696"
     CDS             6836..7051
                     /locus_tag="VW361_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744700.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(7374..7526)
                     /gene="cibB"
                     /locus_tag="VW361_001697"
     CDS             complement(7374..7526)
                     /gene="cibB"
                     /locus_tag="VW361_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU9744701.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7528..7713)
                     /gene="cibA"
                     /locus_tag="VW361_001698"
     CDS             complement(7528..7713)
                     /gene="cibA"
                     /locus_tag="VW361_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU9744702.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7891..8574
                     /gene="tsaB"
                     /locus_tag="VW361_001699"
     CDS             7891..8574
                     /gene="tsaB"
                     /locus_tag="VW361_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU9744703.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8571..9008
                     /gene="rimI"
                     /locus_tag="VW361_001700"
     CDS             8571..9008
                     /gene="rimI"
                     /locus_tag="VW361_001700"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU9744704.1"
                     /translation="MIEIKRIQQQPDLAQAIYTVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8998..10008
                     /gene="tsaD"
                     /locus_tag="VW361_001701"
     CDS             8998..10008
                     /gene="tsaD"
                     /locus_tag="VW361_001701"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU9744705.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKTFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEEYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(10048..11354)
                     /locus_tag="VW361_001702"
                     /pseudo
     CDS             complement(10048..11354)
                     /locus_tag="VW361_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11687..11981)
                     /locus_tag="VW361_001703"
                     /pseudo
     CDS             complement(11687..11981)
                     /locus_tag="VW361_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12088..12381)
                     /locus_tag="VW361_001704"
                     /pseudo
     CDS             complement(12088..12381)
                     /locus_tag="VW361_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12624..>12872
                     /locus_tag="VW361_001705"
     CDS             12624..>12872
                     /locus_tag="VW361_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEU9744706.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVD"
BASE COUNT         3686 a         2538 c         3001 g         3647 t
ORIGIN      
        1 gtcaacggtt catggtacta cctcaacgct aacggttcaa tggcaacagg ttgggtgaaa
       61 gatggagata cctggtacta tcttgaagca tcaggtgcta tgaaagcaag ccaatggttc
      121 aaagtatcag ataaatggta ctatgtcaat ggcttaggtg cccttgcagt caacacaact
      181 gtagatggct ataaagtcaa tgccaatggt gaatgggttt aagccgatta aattaaatca
      241 tgttaagaac atttgacatt ttaattttga aacaaagata aggttcgatt gaatagattt
      301 atgttcgtat tctttaggta cctatcttat gatttcagga aatgtcatta aaaaaacgac
      361 tccttttctc taacttgaaa aatagattag agaaaatggg ttgttttatt tattatagtt
      421 atttgaatga agataagaag aaggtatact cacatcattc acataatctg tatattgact
      481 ataagtttta aaaaacaatt tttaagctct tccttgtctt ctctaaccaa gcgtgttata
      541 atgaatactg ctcaagcgac cttcaatcgt gaagcacaca cgaccttcaa tcgtgaataa
      601 acgaatagat gggagactta ccatgagtga taactctaaa acacgtgttg tcgtggggat
      661 gagtggtggt gttgattcgt cggtgacggc tcttttgctc aaggagcagg gctacgatgt
      721 gatcggtatc ttcatgaaga actgggatga cacagatgaa aacggcgtct gtacggcgac
      781 cgaagattac aaggatgtgg ttgcggtggc agaccagatt ggcattccct actactctgt
      841 caattttgaa aaagagtact gggaccgcgt ttttgagtat ttcctagcgg aataccgtgc
      901 agggcgcacg ccaaatccgg acgttatgtg caacaaggaa atcaagttca aggccttttt
      961 ggactatgcc ataaccttgg gggcagacta tgtagcgact gggcattatg ctcgagtggc
     1021 gcgtgatgag gacggcactg ttcacatgct tcgtggcgtg gacaatggca aggaccagac
     1081 ctatttcctc agccaacttt cgcaagaaca acttcaaaaa accatgttcc cactaggaca
     1141 tttggaaaag cctgaagttc gaaaactagc agaagaagca ggcctttcga ctgctaagaa
     1201 gaaagactcg acagggattt gctttatcgg agaaaagaac tttaaaaact tcctcagcaa
     1261 ctacctgcca gctcagcctg gtcgcatgat gactgtggat ggtcgcgata tgggcgagca
     1321 tgcaggtctt atgtactata caatcggtca gcgtggcgga ctcggtatcg gtgggcaaca
     1381 cggcggtgac aatgcccctt ggttcgttgt cggaaaagat ctaagcaaga atattctcta
     1441 tgtaggacaa ggattctacc atgattcgct catgtcaact agcctagaag ccagtcaagt
     1501 ccactttact cgtgaaatgc cagaagagtt tacgctagaa tgtacggcta aattccgtta
     1561 ccgtcagcct gactctaagg tgaccgtcca tgtcaaagga gacaaggcag aggttatctt
     1621 tacagaaccg caacgcgcga ttacaccagg acaggcagtt gtcttttacg atggcgaaga
     1681 gtgtctaggt ggcggtttga ttgacaatgc ttaccgcgat ggacaagttt gtcagtacat
     1741 ttagattgac aaattttctc aatttgctac aataataaca gcaatagaaa tgatggtcaa
     1801 agctcatgga tgttgcaggc ttttttgtcc tgcacttctt tgtagttttg actgtttttg
     1861 tgtcgtttaa gggaaaggac aagaatgact caacaagact ttcggacaaa agtagacaat
     1921 acggtttttg gtgttcgggc gacagctttg attcttcaaa atcgcaagct tctagtcacc
     1981 aaagacaagg gcaagtatta cactattgga ggtgcgattc aagtcaatga aagcacggaa
     2041 gacgcggtag tccgtgaagt gaaggaagaa ctgggtgtca aagctcaagc tgggcagcta
     2101 gcttttgtgg ttgaaaatcg ttttgaacaa gacggcgttt cctatcacaa tatcgagttt
     2161 cattatctgg tggatttgct tgaagatgcc ccgttgacca tgcaggaaga tgagaaaagg
     2221 cagccctgtg agtggattga cttggataag cttgaggata tccagctagt tccagccttt
     2281 ttaaaaacgg ccctaccaga ttgggaaggc caactaagac acattcatct tgaggaatag
     2341 gagagaaaca tgacttatca ttttactgaa gaatacgata ttattgtaat tggtgcggga
     2401 cacgctgggg ttgaggcttc cttggccgct agccgtatgg gctgtaaggt cctgcttgcg
     2461 accatcaata ttgaaatgct ggctttcatg ccttgtaatc cctctatcgg tggttctgcc
     2521 aaggggattg tcgtgcgtga agtcgatgcc ctcggtggcg agatggccaa gactattgac
     2581 aagacttaca tccagatgaa gatgctcaac acagggaagg ggccagctgt ccgtgctctt
     2641 cgtgcgcagg ctgacaagga actttactct aaggagatgc gcaagacagt tgaaaatcaa
     2701 gaaaatctga cccttcgtca aaccatgatt gatgagattt tggtggaaga tggcaaggtt
     2761 gtcggtgtgc gtacagccac ccatcaagaa tatgctgcta aggctgttat tgtgacgaca
     2821 gggactgctc tccgtgggga aattatcatc ggagacctca agtactcatc aggtcctaac
     2881 cacagcttgg cttctattaa cctagctgac aatctcaagg aactgggcct cgaaatcggt
     2941 cgtttcaaga caggaacccc tccacgtgtc aaggcctctt ctatcaacta cgacgtgaca
     3001 gaaatccaac caggagatga agcacctaat cacttctcat acacttcacg tgatgaggat
     3061 tatgtcaagg accaagtgcc atgctggttg acctacacca atggtaccag tcatgagatt
     3121 atccaaaaca acctccaccg tgcgcctatg tttacaggtg tggtcaaggg agtggggcct
     3181 cgttactgtc cgtcgattga agacaagatt gtgcgctttg cggacaagga acgtcaccaa
     3241 ctcttccttg agccagaagg gcgcaatact gaggaagtct atgtgcaagg actttcaacc
     3301 agtctgcctg aggatgtcca gcgtgacttg gttcattcca tcaaaggttt ggaaaatgca
     3361 gagatgatgc ggacaggtta tgctattgag tatgatatgg tcttgcctca tcagttgcgt
     3421 gcgactttgg aaaccaagaa aatctcagga cttttcactg ctggtcagac aaatggaaca
     3481 tcaggttacg aagaggcagc aggccaaggg attattgcag gtatcaatgc ggctctgaaa
     3541 atccaaggta aacctgagtt gattctaaaa cgaagtgacg gttatatcgg ggtgatgatc
     3601 gacgacttgg tgaccaaggg aaccattgaa ccttaccgtc tcttgaccag tcgtgctgaa
     3661 taccgtctca ttcttcgtca tgacaatgct gatatgcgct tgactgagat gggacgcgag
     3721 attggccttg tggatgatga acgctgggct cgttttgaaa tcaagaaaaa tcaatttgat
     3781 aatgagatga aacgcctaga cagtatcaaa ctcaagccag tcaaggaaac caatgctaag
     3841 gttgaggaaa tgggcttcaa gccgttgaca gatgcggtga cagccaagga attccttcgc
     3901 cgtccagaag tttcttacca agatgtggtg gccttcatcg gaccagctgc agaagacttg
     3961 gatgacaaga ttatcgaatt gattgaaaca gaaatcaagt acgaaggtta catctcaaaa
     4021 gccatggatc aggttgctaa gatgaagcgc atggaagaaa aacgtattcc agccaatatc
     4081 gactgggatg acattgattc tatcgcaacc gaagcccgtc agaagttcaa actcatcaat
     4141 ccagaaacca tcggccaagc cagccgtatt tcgggagtaa acccagcaga tatttctatt
     4201 ttgatggtgt atctggaagg taaaaatcgt agtatttcta aaactcttca aaaatcaaaa
     4261 tgatacgtcg taggcttctt acgaatgagt tcaaagcttg gctttgattc atctccaacc
     4321 tcccatagtt ccccgaacta tgggagctaa ctcaagttat gctttcgctt agccttctag
     4381 tctgattttc attgagtttt aatctcaaaa gaaagcatag agaaaaacag ctccgaagac
     4441 ggggctgttt tgttgacttg tactcaatga aaatcaaaga gcaaactagg aagctagccg
     4501 taggttgctc aaagcactgc tttgaggttg tagatagaac tgacgaagtc agctcaaaac
     4561 acagttttga ggttgtggat agaattgacg aagtcagtaa catatatacg gcaaggcgaa
     4621 gctgacgtgg tttgaagagt attattcttc atctggtgtg aggatcatcg ggatgatgat
     4681 cggttcacgt tcggtatttt catagaggaa ggggcgaata gcgttgacaa tggcaccatt
     4741 gacagattgc acgctagcat ccttattttt cagtgcgata cgaatggcat tgaagaggat
     4801 acgctggctt tggcgaatca agtcgccaga ctctctcatg tagacaaagc ctcggctgag
     4861 gatgtctgga ccagatagaa tcatctgcga tttgaagtca acagttgcaa ctgccagaac
     4921 gacaccgtct tcagatagat cgcgacgatc tttgaggaca gctgcgccaa tttcaccgat
     4981 acgatttcca tcgacataga tatcttgggc gttgaaatga cctgcgatac gagctgagtc
     5041 agcagtaagg gcaagcacat cgccattgct catgataaag atattgtcct tctcaacacc
     5101 agtatccact gctagtccag cgtggacttt ttgcatgcgg tattcaccgt ggacaggcat
     5161 gaagtatttt ggcttaatca agcagagcat gagtttttgc tcttgctgac caccgtgtcc
     5221 agatgtatgg atattgttca ctttaccgtg gataacttcg acaccagctt cagaaatgat
     5281 gttaatcagc ttgttgacgc tagtagtgtt tccagggatg ggactagaag agaagataac
     5341 ggtatcacct ggttgtaatt gtacttgacg gtgggttccg ttggcgatac gagagagggc
     5401 tgccataggc tcaccctgac tacctgtaca gaggataaga acttctcctg caggataatc
     5461 tttgatttca tttggctcga taaaggttcc cttaggagct ttgatgtagc caagatcgat
     5521 tccgttgaca atggcctttt ccatagaacg accaaagacc gcaatcttgc gtccagtctt
     5581 aacagcagct tctgttgcct gctggagacg gaagatattt gaggcaaagg atgcaaagat
     5641 gatacgtcct tcaatacctt ggataatctt catgatggac tggccgacaa ccttttcaga
     5701 gttggtaaag gttggtactt ccgcatttgt cgagtcagac aggagacaga gcacgccttc
     5761 ttcaccaagc gcagccatac ggtgcaagtc tgcaggttca ccaactggag taaagtcgaa
     5821 cttaaagtca cccgtacaga cgattttccc ttgaggagta tgaatgacaa tccccaaagg
     5881 ctctggaata gagtgagtcg ttctaaagaa agttgccttg agatttttaa aggtcaactc
     5941 ggtgttgtgg ttgatttcgt aaagtttggc gttgcgcaag aggccgtgct cttcgagttt
     6001 tccacggatc aaagccagcg caagcggtcc agcgtagatc gggacatttg cttgcttgag
     6061 caggaatgga atcccaccga tgtggtcctc gtgtccgtgc gtaatcaaaa cagccttgac
     6121 gcggtcgata ttgtccacga tgtaagaata atcaggaatg acatagtcga taccaagcaa
     6181 gtcatcttct gggaatttaa tcccagcatc gacgatgata atctcatctt ggtattcaat
     6241 tccgtaagtg tttttcccga tttctcccag accaccgatg gcaaaaacac caacttcttc
     6301 aggtttaaga gtgtaggcca tattagaact ccgtaatttc gaaggcgcca gtttcttttt
     6361 cgtaatcgag caatttgtca gacaagagtt cgatatattc gatattgtac tctgggcgat
     6421 tttcttcgac aagttggcga gcagtgatac ggccctcaag ttctgagctg gtatcgatat
     6481 ctaagtaaag cgcgcgtgtt gtttcacggc gtgggctacg ttcttttgtt tcttgataaa
     6541 aaactttgta aatcatatag ttcctttcta tttacaggtc agcttattcc aaacttttag
     6601 cagatatttg cttgatttca ttccattttg tgtctagatt gaccttgatt cgttacaatt
     6661 atttcaatta taccacaaaa tgaaaaatta gtaaaagacg gaaacgagaa agttagggga
     6721 cgatttcttt ggtaagcgtt tgcaaaaaca aagaaaatgt attatgttga taacggaagt
     6781 gaaatttatt gcttgtcata attccatata gattttaagt caaggaggtt gccctatgta
     6841 taacttattt gcttttgcta tcggagctcg cttggtagct tttattgttt ttgttgcttg
     6901 cgtttatgcg gggaatcttc tatttgccaa actggaacga cgacaaacca agttcttgtg
     6961 gaaaatgacc tttgtgactc tctactcgct ttttctcctc ctcgtgacct atgtcgtttg
     7021 gtttgtattt tactttgaat taaatgctta gatgccctgc ttatgctggg gttttttgtt
     7081 tggggatgta gagatagtag atttacgaca cgaaaattcc accccatcta tcaagatgag
     7141 gtggtctttg catttttcta acatgacatg acaatggaat tttcaaagct tattattttt
     7201 atgggagtca ttgttctgat caaaaataga gttgaagcat aaaaataaaa caatacaaac
     7261 agataaatcg aatggtaaag ggatggtagt aatgttcaaa tcattgagaa tgctgagcaa
     7321 actgtaagag atgaagacaa taaaatttat ccttctaaaa atgtgtttct tatctagcat
     7381 gacttaccaa actttttacg aaggtctttt ccaatggtat aacctgccat aaataaagcg
     7441 ataccaacac cgacaccaaa gccacccttg atttcttgca attccttatt agaaatttca
     7501 cgataattgt tcaaatcttt catcatatta atctcctcct aaaaaataac cagctgccaa
     7561 accagaacct ataagtgctg ttccacctgc aatagccttc caagatactg ctactccaaa
     7621 gataaccaag ggagcgagac cgccatcaat atctgataat tcattttcag ataaggataa
     7681 aaattgattg tcaagaatgt caaaatttgt cattgaactt tcctcctttt ttcttgttca
     7741 cttttatatt cggaaaagaa aaggaaaagt gagcattttt ttaaattatt tttagttaag
     7801 tgagggcact cttgtctggg ggcaaagaaa attcccatgt gccagctttt gtagtataat
     7861 agtaagcaga caaaaagata ggaatgtgtt atgaaagtat tagcttttga tacgtccagc
     7921 aaggctcttt ctctggctat tttagaggat aagcaggttc ttgccgagac gacgattaat
     7981 attaagaaaa atcacagtat tactcttatg cctgccatcg attttttgat ggcaagtttg
     8041 gattggacac ccaaggattt ggaccgaatc gtggtagctg aagggccggg tagctataca
     8101 ggcttgcgaa ttgcggtagc aactgctaag accttagctt acaccctgaa catcgagttg
     8161 gttggtatgt cgagtctctt ggctctggtg ccccaccaac aagaaggttt gtttgtcccc
     8221 ttgatggatg cgcgtcgcaa taatgtttat gcaggatttt atgaaaatgc caaacctgtc
     8281 atggcagaag cgcacctatc ttttgaagag gtgctagaaa aagtcaaggg tactagtcag
     8341 gtaacctttg tcggagaagt tggccccttt gttgagcaga ttcaaaaaca cttgccaagg
     8401 actgattaca aagaaacatt gcccaatgca gctaatctag ctcttttggc ctgggacaag
     8461 gaagcagact ccttgcatga ttttgtgccg aattacctca aacgagtcga ggctgaggaa
     8521 aactggctca agaaccatac cgagtctggc gagtcttaca ttaaacgcct atgatagaaa
     8581 tcaagcgaat tcaacaacag cctgacctag ctcaagccat ctacactgtt atggcagctg
     8641 tttacctagt cagtccttgg actctggagc aaatccaagc agatctgtcc caagaccaga
     8701 cttggtatgc attggcttat gatggggcag aagtgattgg atttctagct gtgcaggaga
     8761 atctttttga agcagaagtc ctgcaaatcg ctgtcaaagg agcttatcag ggtcagggaa
     8821 ttgcgtcagc cttgtttgct caattgccga cagacaagga aattttcctc gaagtcagac
     8881 agtcaaatca acgagcgcaa gcattttaca agaaagaaaa gatggcagtt atcgctgagc
     8941 gaaaggccta ctaccatgac ccagtcgagg acgccattat catgaagaga gaaatagatg
     9001 aaggatagat atattttagc atttgagaca tcctgtgatg agaccagtgt cgccgtcttg
     9061 aaaaacgacg atgagctctt gtccaatgtc attgctagtc aaattgagag tcacaaacgt
     9121 tttggtggcg tagtgcccga agtagccagt cgtcaccatg tcgaggtcat tacagcctgt
     9181 atcgaggagg cattggcaga agcagggatt accgaagagg acgtgacagc tgttgcggtt
     9241 acctatggac cgggcttagt cggagccttg ctagttggct tgtcagctgc caagaccttt
     9301 gcttgggctc acggacttcc gctgatccct gttaatcaca tggctgggca cctcatggcc
     9361 gctcagagtg tggagccttt ggagtttcct ttgttggcac tcttggtcag cggtggccac
     9421 acagagttgg tctatgtttc tgaggctggc gattacaaga ttgttgggga gacacgagat
     9481 gacgcggttg gcgaggccta tgataaggtc ggccgtgtca tgggcttgac ctatcctgca
     9541 ggtcgtgaga ttgacgagct ggctcatcag gggcaggata tttatgattt cccccgtgcc
     9601 atgattaagg aagataatct ggagttttca ttctctggtt tgaagtcagc ctttatcaat
     9661 cttcatcaca atgccgagca aaagggagaa agcctgtcta cagaagattt gtgtgcttcc
     9721 ttccaagcag cagttatgga cattctcatg gcaaaaacca agaaggcttt ggaggaatat
     9781 cctgttaaaa ccctagttgt ggcaggtggt gtggcagcca ataaaggtct cagagaacgc
     9841 ttagcagccg aaatcacaga tgtcaaggtt atcatccccc ctctgcgact ctgcggagac
     9901 aatgcaggta tgattgccta tgccagcgtc agcgagtgga acaaagaaaa cttcgcaggc
     9961 tgggacctca atgccaaacc aagtcttgcc tttgatacca tggaataaag agtggctctt
    10021 tgtcaagtgt agtgggtagg cgaaaagtta caatctggag agtacgaaat tcgtactctc
    10081 ttttttgatg ttcaaagtca tcaaaatccg ttttttaaaa ttgttaaagt tccggaaacc
    10141 aaaggctttg cgcttgataa ccttaatcaa attattggtc gcttcaagtt tagcgttgga
    10201 ataaggcagc ttaagtgcgt tgataatctt atctctatcc cttaaaaaag tccaaaagac
    10261 cgtttgaaaa agcggatgaa ccgttggcag ttcttgctca atcaatccaa agaaatggtc
    10321 ggcattcttc tcttgaaaat gaaagagcag gagttgatag agttcgtagt aaacctgtaa
    10381 tccctcagag taagaaagca gcttatctcg tacttcccga tgggttaagt gcattcgaaa
    10441 cgtgggctga tagaatcgtt tctgacagag cttgaagcta tcctggtgta gtaaatcagt
    10501 ccagtggact gatttagccc gagcctagaa acgaaaaagc gagggttcca aaagcgcttg
    10561 agcgcccgat actccaagga ttttcggtca aattggttca tgatttggat tcgtactcgg
    10621 ttcatagctc ggctcagatg ttggacaatg tggaagcggt caagaacaat cttcgccttt
    10681 ggaaagagct gcttagcgag ccgataataa gggctgtaca tgtccatggt gatgacctcg
    10741 accagctccc gaacctctct ctgatagcgt tggaaatggt ttcgaatcac cgcatgagtt
    10801 cgcccgtcta aaattgcgag gatggatttg gactcaaaat cttgggcaat gaagctcatt
    10861 ttgctctttt tgaagctata ctcatcccaa ctcataactt ttggcaactt ggtccaatcg
    10921 gtttcaaact taaattccct cagttttcgg atgacggtgg aagttgagac cgccaatctg
    10981 tgggcaatct cagtcataga ctgcttttca aggaggagct gagcgatttt ttgtctcacc
    11041 atgttggaaa tctggcaatt tttcttgaca atggatgttt gagaaacgac caccttaagg
    11101 caattcttgc actgaaagcg gcgctttttg agatgcagta ccgtgggtaa accctgacag
    11161 tcgagaagcg gaattttaga ggctttctgg aagtcgtatt tgatcatctt cccttgacaa
    11221 tgaggacaag gaggagcggg ggaatccaac tttgcctgaa cgactagatg ggtttggtat
    11281 ttcagaacag acaagatttt gatatttttg tcttccaatc cgagcaaatc tgtggtattc
    11341 ttaagttgtt ccatatgaac cctttctaat gagttagtta gacgcttttc attataggtc
    11401 atatggggct ttttttctac aagaaacgac cctataattc ctggggtggg attacccact
    11461 acagaaatta tagagccaaa gcattccaaa gtcttgtctg actctggaat gttttctgtt
    11521 cacagttgtt ttgtaactgc ctaataagta accgcgctat aacgaggtat ctaccgagat
    11581 tgtcaattct ccagtatact gttataaaaa acaaaactgg aggatttttt tatgtccccc
    11641 catcgtccca tcgactgttc cgtagctgcc caataacgga gtataatcat ctgaaacaag
    11701 aataggacaa aagtgcctca agaaaagcat cgtaatttga caatattatt ctgagatgtt
    11761 tttgatgtaa gcccatattt tctcaatggg attatactcg ggtgaatagg taggaagtgg
    11821 taacagtcta tgccctgctc cttacacatg ttcattctgt gaaaccttgc attgtccata
    11881 atgataaggg atggtgtatc taaagtaggt agtaagaatt tttggaagca agcttcgaaa
    11941 aagtcactcg tcatcgtatc tttataggtc atcggagcca tagtatattg aaacaaaaaa
    12001 gggcattagt acttctataa cagtatcgca atctctggtg tgcgttgtct cgatcttaat
    12061 tcaaataatt atatcttctt ccagagagac taactgcctg ctcaaggctc gatcatattc
    12121 gagataaaaa taggtctcaa cccctgtctc ataaatataa ataggagtca ggtagcttaa
    12181 gtgattcaat tctttaagga accgatttac tttttctggg tcttgttcgc agtaggtacg
    12241 gctctttttt agactatatc ccatagcctt tagagcgtaa tgaatagttg ttggaggaca
    12301 gttgaattca gcagctattt cagtcaaata agcatcggga tgagtttcaa tatagatctt
    12361 taatttatct ctatcaactt tttcaattaa tagtggaagt tttcttaaag ttagtgtgtt
    12421 gaaacgtttt tatacagtgc taaaatttga agtgtagtgc agatgtattt gtaatagtat
    12481 tatagcaatt ctttggagaa ggtcgagaca agagaaaata ggtatctttg agatataagc
    12541 atgatttact ataaaattat tgagttattc ataaaaattt ttctatcaaa tatcataatg
    12601 cgtcgtttaa ggagatggtt acaatgcaat atagttgtgg aaaaataaat attaatatcc
    12661 ctgatggata tggagacatt aaggatatag tgttttcggc tcatattata gttaggtata
    12721 ataatggaca ttgtggaggt atagatccgc atataattgg actttgtaaa aagcagatca
    12781 gaaggatgtc tctatatcct attttgataa tcgtatctag agattcaaag gttattgatg
    12841 attataaaaa tttagatatt gcctatgttg at
//
LOCUS       DAVKMO010000052        12289 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVKMO010000052 DAVKMO010000000
VERSION     DAVKMO010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12289
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.052"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            135..317
                     /gene="rpmF"
                     /locus_tag="VW361_001706"
     CDS             135..317
                     /gene="rpmF"
                     /locus_tag="VW361_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU9744707.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            333..482
                     /gene="rpmG"
                     /locus_tag="VW361_001707"
     CDS             333..482
                     /gene="rpmG"
                     /locus_tag="VW361_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9744708.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(904..2784)
                     /locus_tag="VW361_001708"
     CDS             complement(904..2784)
                     /locus_tag="VW361_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9744709.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLATVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERMLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAGTIADIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RHAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2778..3647)
                     /locus_tag="VW361_001709"
     CDS             complement(2778..3647)
                     /locus_tag="VW361_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9744710.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGVSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAATGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVDNFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3731..6376)
                     /locus_tag="VW361_001710"
     CDS             complement(3731..6376)
                     /locus_tag="VW361_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU9744711.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(6467..7747)
                     /locus_tag="VW361_001711"
     CDS             complement(6467..7747)
                     /locus_tag="VW361_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU9744712.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDSLLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEKNWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCDVNDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7918..10002
                     /locus_tag="VW361_001712"
     CDS             7918..10002
                     /locus_tag="VW361_001712"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU9744713.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGEDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGTSIRLKQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKSSAQVDWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEINESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMTPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFEITGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(10042..11721)
                     /locus_tag="VW361_001713"
     CDS             complement(10042..11721)
                     /locus_tag="VW361_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU9744714.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPAYG
                     NGGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGNCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELDYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPTLSADFAYRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIQVLAFQAGETEKSLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
BASE COUNT         3374 a         2947 c         2492 g         3476 t
ORIGIN      
        1 cgtgtcggat aggagaattt tttcatcttt ttttgtcaag taactttact ttacaaaaaa
       61 aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt gaatcgaata taaataccta
      121 aaggagaaat caaaatggca gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac
      181 gtcgtacaca ctacaaagta acagctccat ctgtaaactt tgacgaaact actggagatt
      241 actcacgttc tcaccgtgta tcacttaaag gatactacaa aggacgtaaa atcgctaaag
      301 ctgcatcagc tgaataatag aagggagata ccatgcgcgt aaatattaca cttgaacaca
      361 aagaatctgg tgaacgcttg taccttactt ctaaaaacaa acgtaacact ccagaccgcc
      421 ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt tgtgtttaca gaagttaagt
      481 aagcattcaa tacgaatcaa tacagaagaa aaacgcttga tcagcgtttt ttctttttgt
      541 taatttcact atattgcaag ggaaatcatt cgaatgacta cattattgat aatatttgtt
      601 aagccatcaa aagtaattaa catttcatag cgagtaatcc tatttaaact cgtcccacta
      661 tctatttctt cttatctctg tgttataatc ccgactttat cataagtttg tctaactgta
      721 gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt
      781 tcttgttttc atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
      841 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
      901 gtattaagtc gtataaatcg tcgaagctgt cgcaatggta tgccactggt tagctgtagt
      961 tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa cttccagctc
     1021 gtcgatacgg tcaagctggc cagccagata aacctcgata cggctttctg ctcgtttgat
     1081 gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga ccttgttttc
     1141 tttcagccat tggtgactaa agagggcatg gaagtcttca atttggcttc taagttctgg
     1201 taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt aggcatgacg
     1261 aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg cctgagtttc
     1321 aaagagataa gcatagtttc cagctttttc tttaatgtca gcaatagttc ccgccgcctg
     1381 agcgaagtgt ggcttgtcct gttcaggtgt catgtgtcgg tcaagtatcg gacagagaac
     1441 atcctgataa aagacatagc ggttgggatt gatgccactg agattacctg gtaggtctgg
     1501 taagaggttg gcaagatcaa tctgcataaa atcctcaacc gttagaccag tattggtctt
     1561 gaaatgcgca gacaaactat ctaggtcatt gcgatagctg agttctgccc agatttgcaa
     1621 gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac ccgttacgat
     1681 gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca ctagacggct
     1741 aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa atgcaaggtc
     1801 atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc tatcctgata
     1861 ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga cacgagtttc
     1921 ctctggaatt tccacatcac ggtcgtactg gccatccgct gacatgagtt tgaagaacat
     1981 atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca tgcgctccaa
     2041 gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt agcgtcccaa
     2101 accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca gtttagacaa
     2161 cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga gaagaatgtc
     2221 ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg ccgacaagtg
     2281 ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgagcat aggcttcgat
     2341 ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag gctgtccttc
     2401 aatctggtaa gtgtcttcca tgtaaagctc aaaggttgag tagcccatga gagccaagac
     2461 ctcaatcatc tgcttggcag aagcgacatt cagcaccgca tttcgagaac agtcaaccat
     2521 gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag cttctgctag
     2581 aactgttgcc aacaaggaca aggcacgata aagttggtga ggtttgcggt aggtcaattg
     2641 atagtgacct tcctcaccct cgatagagat agaggcttgg tcagactgag tgacagccac
     2701 ttccacatct ggtagagaaa tgtgaccttt taaaacctca atagcttgcg tttgtttggg
     2761 actaagtcct ataaatctta ccattgcttt tcctcctgta gccagttgac aagggcaccg
     2821 tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac cgtgtattct
     2881 tcgtaggcat cgacaaagtt atcaacagcc ttcttgacac cttggataaa atctggattt
     2941 tgactgatag agccacccag actgatgaca tctggatcga tcagatactg aatattgagc
     3001 aagccttgcg ccagattgcg gttcatgcgc tcaatggctt cttgacaaag agcattacca
     3061 gttgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga tttttcaata
     3121 acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag tttttcagca
     3181 ggggcaaggg ttgtcatgta accaaattct ccacccagac cgtggcgacc tcgatgaagt
     3241 ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca ggctgcattt
     3301 tcaagctctg gatgagctag tagttcactg actccaacgc agttggcatc attttctaaa
     3361 tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg gatgtagggc
     3421 accgcactga agccatcaat cacacctgtc tcttgattga ccgcacctgg aacgctcata
     3481 gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag taaatcctcc
     3541 aagttttcag gcgttgaaat acttgtctta tccagtattt tcccatcagg agtcagactg
     3601 gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt ttttaccata
     3661 aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt ttgatgttta
     3721 ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct tgtggagcca
     3781 atagtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt tgttgatgtt
     3841 ctgatatgcg cacattttct tgactcatat tatagtaacg gaggacatag ccttcttcat
     3901 tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca gaatggctca
     3961 agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg ctggtaaacg
     4021 gtgtctgcaa ggctttggca cgacgatagg ctgagaagcg ttcttgggct tggtggcatt
     4081 caatcgcaaa ttcgacttca aactcacgca agcattgtgc ttctggcgtt gggaagtagc
     4141 cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg ttatccccaa
     4201 ggatttcgta ttcattcaat cccttgttgg atacagtcac ccctttttca tcgtcataca
     4261 gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa gcagctggtt
     4321 tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga cgcgtgttat
     4381 gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag cgagtcttga
     4441 agcggatttg tggattgtca acaaagacaa tcaactcagt ttccagagga atgtttgtca
     4501 attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt tgctcttctt
     4561 ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag attttagcat
     4621 agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt ggctctgttc
     4681 cttttggttg gaaatagata tactcgtttc cgatgtcccc acggtcttcg aagcggataa
     4741 agtcttcata ggcttcgtga gttgtcttgt catatactgt gatattgtca tccacactca
     4801 ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg tgttcttgtt
     4861 ttccttccag caattggaag gttgtccaag aaagcggcgc taggtgaact ggaatggtca
     4921 cgcgcacttg tcgagcaata cgagcttggc ggaacttgtc ttttggtaaa tcgtactcaa
     4981 aattagctcc gaggtcttcg attgtagcct ctacaggacg accatccaag tcctccacac
     5041 ggtaacttgg taagataaga gcagccatct ttttgtagcc ttctgttggg tgcaattcct
     5101 tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta tcatgcaagc
     5161 ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca attttaccct
     5221 tccactcgtt gagcaagtta cttttaacaa agtttcctac ttggttgacc ttggcaaaac
     5281 gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta tcatgtggcg
     5341 cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg tgtccaccag
     5401 tgataatagt caagggttct accacttgct ctaggaggtt gctattttct tggaaggctt
     5461 gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct
     5521 gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct tctacagctt
     5581 gaacatattc atcaaaagaa ctatgaacaa agattacatc cgggaagagt tcatttgcca
     5641 cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg ttcatcatca
     5701 accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc cagaaggtca
     5761 aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagttg gcaaagagaa
     5821 tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac tgggatgtaa
     5881 accgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca cgaccaaagg
     5941 ctgccacgtg aatacctgat ttttgaagga tttgaggagc ttgtcccata tttccaaagg
     6001 tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct tgttgaccaa
     6061 tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc aagatgtaaa
     6121 agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtca cgattttcag
     6181 ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg aaactcttga
     6241 actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc aactgcatac
     6301 gatggctttc aaaaggcaag taccactcac ggtcccagtg actatgtgag ataatatgta
     6361 caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac gttttaaatg
     6421 taaacttgtg attctgataa gaatcggttg agctaaagcg agccccttag cgaatatcca
     6481 agtaatccaa gaccaactca cagaacatca tgttagccca ggagaaccat tcacgagagt
     6541 agagggtcgg atcatctacg tggaagcttt cgtgcatgac acctgtacca ccatcgcagg
     6601 caaccagctg atccagcaag aattttttct ctgccttatc tcttgttgtc aatccttgga
     6661 tagaaagggc gattggccag atatagcgat agaaggtatg agaacttccg agaccgctag
     6721 cgtattctcc ttggtagaag tatggatttt cagagctcaa aatggtacga cgagtagctt
     6781 gatacacttc atcgttgaca tcgcagtagc ccagataggg cgcagctagt agacttggta
     6841 catttggatc atccatgatg ctggcatttc ctaggccatc cacttcaaaa gcgtaaatct
     6901 tttcgccctt gctgttggtg gtgtaagcgt agttttcgat tccttcttgg atttcatcct
     6961 gaagacgctt ggcatcagca ataacactct ggctatcagc taggtttaat gctgcgaaga
     7021 tttcttgcac ataacccaag actactacag caaacatatt tgacggaatc aagtaactat
     7081 actgacagca gtcatcgctc ggacgaaagg ctgaccaagt cattcctgtc actgcaaaat
     7141 caggtccaaa gccatcattt accaaggtgt cttccttgcg gtccgtatct cggacaaaac
     7201 gataaggaga gttcttgtgg tcttgttcca ccgtccacag atggagaatt tccttagtcg
     7261 ctgcgacaaa agtctcatca aactgactag tctcgccagt ttctttccag aggagataag
     7321 ccaactgcaa aggatagcaa agcgagtcca cctcatactt gcgttcccag atccagccgt
     7381 taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt cttctcaatg ttgaaggagt
     7441 tagcataggg atccttgagt accaaggtca tctgacgttt gaccaaacct gcaatggtct
     7501 gacgcaggag ggaatctctt ttagctacat gaaggtaggg tctgagttgg gctgtcgaat
     7561 ctcgaagcca catggcagga atatccccag tcaagacaaa agttgaacca tcttctaaga
     7621 tttcaaccgt attgtccaag gtatcggtgt agcaacgctc aaagacatca acccactctg
     7681 gatggtcctt ggcccgctct gctacttcat ctagccattc tctaacaatt tctttcgaat
     7741 aaatcatcgt gcaattccct ctttcaaaca agtttcatgt tcagtatata gcttttgaga
     7801 cagaaaatac atacacaaat gatagtcatt tttctacaaa atagttatct ttaaaactcc
     7861 ttttctaaag gccctctttt tctgatataa tgtagaaaaa cagctaaagg aaagactatg
     7921 aaaccactac ttgaaaccat cgatacccgc tttggtactg ctagcaagca tgccttctct
     7981 cggggaaata ccctgccata cacaggcgtg ccttttggga tgaattattt tgtgccccag
     8041 accagtgacc aggacggagc ttggttcttc gatccgcatc tgcctatctt tcaggggatt
     8101 cgattaactc accagcccag tccttggatt ggggactact cttggctcct tctgacacct
     8161 gtcaccagtc aactgggtga agacagtctc tttcaccgcc agtcttctta tgatatagat
     8221 aaagcttgct tccaacctca ctatttgaag ctcttttctc tgcgttatca gattgaaacc
     8281 cagctcacac cgacttgcta tggtacttct attcgtttga agcaaaagca aggcaaagcc
     8341 ctctccctct atcttcacgc agcagatgaa ctgaccgtag agcaagtaga taagcggact
     8401 cttgccctgc gacaagaagg taaaactgaa actaacaaaa attcgctaac gatgttcact
     8461 gccctgcaaa tgaacacgga tattcttgct atcagccaag aagctgggga ctggcgaatt
     8521 gacttagcaa gtagtcaaac cgagatgcaa ctagccactt ctttcatctc tccttctcaa
     8581 gctctaatca atctacctca agaagatttt gatagctgta aatcaagtgc ccaagtggat
     8641 tgggaaaatc tcctccatcg ttttgacatt atagagacag gagaggctga ccgaaccttc
     8701 tttgaccact gcctctacag actcttcctc ttcccacaga ctttttatga gattaatgaa
     8761 tcagggcaag ccatccacat ggatctggct actggtactg tcaagcctgg tgtcctcttt
     8821 agcaacaatg gtttctggga taccttccgc accaccttcc ccctctttgc ccttatcata
     8881 ccggagcact atcaacgctt tttagaaggt ttcctcaata gctaccgcga tactggtttc
     8941 cttccaaaat ggctggctcc agatgaacgg ggtatgatgc caggtacact tttagacggt
     9001 attatcgcag atagcgcctg caaggacatg acccccgacc tagaaggaga actcttccaa
     9061 gccatgctcg aaacagccag caaagccgac cctctcggca tcaatggccg ccacggacta
     9121 gcccaatacc aagaactagg ttacctctct accgaccacc acgaaagtgt tagccatact
     9181 ctagactatg cctatagtga cttttgtatc gccagctgtg ccaaaaaact agagaacata
     9241 gaaatcgctg aaacctacaa ggctgcttca caaaattacc gccagctatt tgacgctgag
     9301 acaggttaca tgcgagcacg agacaatcaa ggaaactttc accctgactt ctctccttat
     9361 agttgggggc gagactacgc tgaatgctct gccattcaag ctactttagg cgttctccac
     9421 gacatccctg gcttaatcca actgatgggt ggaaaagaaa cctttagcaa ctatcttttg
     9481 aaagcctgtc aagatgctcc cctctttgaa ataacaggct atggttacga aattcacgaa
     9541 atgagcgaga tggctactgc tccttttgga caaatagcca tttccaacca gcctagtttc
     9601 cacattcctt atctcttccg ttacagcgat taccctgact acactgccct tcttatcaag
     9661 acgctccgtc agaaagcttt tcacccaagt tgggaagcct atcctggaga tgaagacaat
     9721 ggtagtctct ctgcttggta catctggtca gctctcggat tttatccaac ctgtccagga
     9781 aaaccaagct atgacctcgg aatccctctc tttgaccatc tacgagtcta cctagctaaa
     9841 gaagataaat ggctggatat ccatactaaa caaaaccaca accattttaa ctttgtcaaa
     9901 gaatgccgac tggacaaaac actcgtatca actattcaac accaagacct cttaaaagct
     9961 gaacaactaa ctttcaccct cagctggtta ccaagtcact aataaccaaa agaacctttg
    10021 catcgcgcaa aggttcttct tttatgaaac ttgaacttga agttgatcca caagctgacc
    10081 atccaccgtt aggttcagat agaaatccaa ggttttatct cctgcgaaat acaaggttgg
    10141 tagcgtcaga cttttttcag tctcaccagc ttgaaacgca agaacttgaa tctcatcctg
    10201 ataggcgaca ccatggacac ctgtccccgg ttgaatcgaa atcttagctt ctaaaggacc
    10261 actacattct ctgcgcttaa ctgtaaaata ggcattttct ccctttgcca cagctaggct
    10321 tttttctgca aatgctagtt cctgaacaac ttcttttttt gataatccag gagttttata
    10381 aagagaaatc ttggtcaata cagggataga ttgtgcctcg gtaatcatca cgcgcacctt
    10441 ttgtgcctct actagcggac ctcgcaagag gcgcttatga ccaactgtga agcccctgcc
    10501 aaactcctgc cagacaccat ccacctctac ttgcacatga aaagcagcga ttcgttgccc
    10561 tagcttcaaa tcttctctta actcaattac atcaaaagtt ttaggagaac ctaaatcgag
    10621 ttctaactgg atgggcaagt ctgcatcgct tgcccaagag ctggtctcaa ggccgtctgt
    10681 caaatggcga taagcaaagt ctgcggaaag agttggacca gatacctcag ctcccagagc
    10741 caaatcttct ttatagagct cattgcgata ggtcgcaaat tcataaagtc gttcaatatc
    10801 ctttgcatca aagagcccag cttgattcgg cggaatatta agcaagagtg gagttcctcg
    10861 ccctactgag tgaaagtaga tttcgaccaa ctcctcgaga gacttaggat cctgatcctc
    10921 atggtagaac cagcctggac ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc
    10981 cgagggatcc ccgtgctgaa gatagtccag ctctgcttct gttcctagtt tatcaggatt
    11041 caccttttgc cacagtggat cacctgcata ccctcgttca ttgccaatcc atcggatact
    11101 ggtgccttct gttgaaaaaa tcaagcaatt gccctgcagg tcacgaatgg tttcaaacca
    11161 tttttcaaat tcataattaa ccttttgcgc gccctctcct ctggcaccat ccatccaaac
    11221 ctcagcaaat ttccctccat ttccataggc aggatttgat aagatttcct tcagctgagc
    11281 cagataatag gcattgtagt ccgcttctcg gtccacatga tagaggggac tatgggcatc
    11341 ccacggtgac aggtagaccc ccatatccat atcaaactct gtggcagctt gggatacttc
    11401 aaggagcaag tcgccctttc ctctcctcca aggactgacc ttaaccgaat aatctgtgtg
    11461 agctgtcgga taaaggacaa agccatcgtg gtgcttgacc accaaaatca actttttgaa
    11521 gcccgtttcc ttgagcacac gaacccactc acgcgcatcc aactgactcg ggttaaagcg
    11581 ctcaggatcc tcctgtccag tcccccattc ttggtcataa aaggtattag gaccgaagtg
    11641 gataaaagct gctagttcat ctcccagata agctagctga gtctgacttg gtaacggtcc
    11701 atgcggtttg attttcttca tcgttatata tctccttctt ttgcaacttc tcttgttcac
    11761 aaggttatcc acaggttgtg gataataaac catgatctaa cagccagctc tttccaactc
    11821 caactggtag gctcaggatt tttctcctca atgttccctc ttcaaacagc tctgtcatat
    11881 ggttctgcta acacctctca gaatgctact ctccataatt attctcaggc ttctttcagg
    11941 tcattgtgtg aagaccattc actctccaga cttttccaca gattgtgaat aagtgattat
    12001 tctaagctat cacctcgtcg actataacaa aaaataaaaa gagggtcaat aagataatta
    12061 tctcttccta aatactcaga aaagattcta taatttgtac aattgaacaa gaaatgcttc
    12121 tccaaaatct atcttcaaaa gaatgttgca tctttttatc ctttcacaca aacatttctc
    12181 tttatacaga tccaagtgat aaccagatga taattggaca ctttttggtc atttgtatat
    12241 tttttgaaaa attttttaaa aaaattttat atccttttta tagaagttt
//
LOCUS       DAVKMO010000053        12031 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVKMO010000053 DAVKMO010000000
VERSION     DAVKMO010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.053"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            11..295
                     /locus_tag="VW361_001714"
     CDS             11..295
                     /locus_tag="VW361_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744715.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            288..526
                     /locus_tag="VW361_001715"
                     /pseudo
     CDS             288..526
                     /locus_tag="VW361_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            622..840
                     /locus_tag="VW361_001716"
     CDS             622..840
                     /locus_tag="VW361_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744716.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(1212..3536)
                     /gene="pflB"
                     /locus_tag="VW361_001717"
     CDS             complement(1212..3536)
                     /gene="pflB"
                     /locus_tag="VW361_001717"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU9744717.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            3885..4946
                     /gene="dinB"
                     /locus_tag="VW361_001718"
     CDS             3885..4946
                     /gene="dinB"
                     /locus_tag="VW361_001718"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU9744718.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMNISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            complement(5093..5938)
                     /locus_tag="VW361_001719"
     CDS             complement(5093..5938)
                     /locus_tag="VW361_001719"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU9744719.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            6194..6975
                     /locus_tag="VW361_001720"
                     /pseudo
     CDS             6194..6975
                     /locus_tag="VW361_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7354..9243)
                     /locus_tag="VW361_001721"
     CDS             complement(7354..9243)
                     /locus_tag="VW361_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU9744720.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPMTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKEQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSTAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            9381..10946
                     /locus_tag="VW361_001722"
     CDS             9381..10946
                     /locus_tag="VW361_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9744721.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWGLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            10946..11686
                     /locus_tag="VW361_001723"
     CDS             10946..11686
                     /locus_tag="VW361_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9744722.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFSNPKEDRTKEFLQRYLK"
     gene            complement(11795..12010)
                     /locus_tag="VW361_001724"
     CDS             complement(11795..12010)
                     /locus_tag="VW361_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744723.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
BASE COUNT         3755 a         2505 c         2288 g         3483 t
ORIGIN      
        1 gaggaagaca atggattggt acgattatat gatacaggca tccaaacaat cacaattcaa
       61 cgcaagccat tggtttcgct atttgcgaaa agttattttt gaagactatt cttatttaac
      121 aaaccaagat gtagaaaagt tgctagactc caaagaacta acccgttttc aaaaaattag
      181 cttgaagtat gcctttcaag agcatactcc aactcataaa tatgtgattt cattaaataa
      241 acctgctaag ttaaccaatg ttcaaaaatt gatggagaaa tacaaacatg gataaaatga
      301 aaccggtctt ccaagcccta aataagaaat taattcagga aaatctgact ttaacaatta
      361 tggttatgtc ttagaatatc atggtttacg tgccacacaa gatgttgatg ctttttatga
      421 ccaaaatcag aaaatcaatg aaattattgc tcgtgtagga aaacagttta atcttaacat
      481 ccacgaagag ttatggctca acaatcatgt tgcaaagcaa atatgaacaa acaacctccc
      541 ttaagtttat gcgaatcctt gtactcattt gagaatctga ccgttttagt agtccctatt
      601 gagtatgtgt taggaatgaa gatgatgagt atcagagagc aggatttgca agatattggt
      661 gcaattatta aatacaaaaa ctttcattca ccattcgata cctttaaata tttaaaagac
      721 atgggatttg atactattga cctctctgtt ctattagaag gttttagtta tgcttatggt
      781 atggattggt tagaaaaatt ttttaaagaa aatcaagata aacttcgcga attttattaa
      841 cagtatcaaa caagatgatt gtcaattagc cagtcgtctt atttttatga tgaaatgaaa
      901 tgaaataaaa tcggaacaaa tcacttagag aattccagtc aatttctagc actgtttgag
      961 ccgtttcagc ggactatagt aaaatgaaat aagaatagga caaatcgatc aggacagtca
     1021 aatcgatttc taagaatgtt ttagaagtaa aggtgtacta ttctagtttc aatctattat
     1081 atttcagatt cggtccacta ttccttccca aaaacattgc atattgcgcc gaaggaattg
     1141 ctcatactat cccaagcaca aaaccctcag tcgtttgacc gagggttcct ttttattatt
     1201 caagaacttg attagctcaa tgcatccaag gcgtcatcca ttgaaagaac ttcgtggaag
     1261 acacgttgtg tcaattcagt tttttgttct ggagtgaggt atttagtgtt tacacagtat
     1321 ccagagatac gtacgataac gtcttcgcct gacatgattt tttcgtaaac atcgttcaag
     1381 tccataacgt tcaagttaac gtgttgtcca ccgttttcga agtaaccatc aaggattgtt
     1441 accaagttat caacttgttc atcacgagtc ttaccaagag cgcgaggtga tacttgtgta
     1501 gtcaatgaga taccgtcagc tgcataacta aagtcaaggc tagaaagtga gttcaagttt
     1561 tgcaaccaac cacctttagc tttgttagat gggttagcac ctggtgagaa gaattcaagt
     1621 ttagacaagt tcacagaacc atcttcgttg aggtatacac ctttgtgaac tggtgagtta
     1681 ccagtttgtt tagagtaagc aacgttagat gtgattgtca aaagtgatac tgtagcttct
     1741 gcatctttgt atagtttgtg gctacgtaga cgagttgtgt aagcttcgat caaccattct
     1801 gccaattcgt ttgaacgtgg gtcatcttca ccccagcgtg ggtagtcacc gattgtttcg
     1861 taatcgtaga tgtagccatc ttcgtcacgg attggtttaa ctgtagcgta tttgatagct
     1921 gacaatgtat caacagtgtt agcaaatcca cagataccga atcccatgtt ggcacgttgt
     1981 ttagttggca agaaggccat ttgaacagct tcgtagttgt acctatcagt catgtagtgg
     2041 atgatgttca aggcatctac gtaagtgtca gtcaaccagt caagagattt ttcaaagttc
     2101 gctttaactg attcaaattc aagaacttcg tcacggattg gttcgatatc aaatactttg
     2161 tagtctttgt gaacatcgtc gtaaccacca ttcaaaccag taagaagggc tttaagaacg
     2221 tttacacgag caccgaagta ctggatgttg tggcgttgtt cttcattttc tggatcaagt
     2281 ggagacacac agcatgagat acagctcatt tcaccatatc cgtctttagc cattgttgtt
     2341 acaccttcgt attggataga agagtgtttg tggctcatgt gcatacagta gcgacggaag
     2401 ttgtatggca atttgtcagt ccaaagaact gtcaagtttg gttctggtga gttaccgatg
     2461 ttgtcaagag tgttcaagaa acggtagtcc atcttagtaa cacggtgacg accgtcgtta
     2521 cccataccag ccatagaagt tgtgataaag gttgggtcac ctgagtacaa ttggtcataa
     2581 gctttggtac gagcaaattt aactgtacga agtttcataa cgaaatcatc aacgaattct
     2641 tggatttctg attcagtaaa tgtaccacga gcaaggtcac gttctgcaaa gatgtccaat
     2701 acgattggta cacgacctag agatgtagca gcaccgttaa tcacacggca gacagccatg
     2761 aaagcaatgt taacccattg gattgcttct ttcacgttca tcgctggttt gcgaacatca
     2821 accccgtaaa ggtcacccag gcgaacaact tgttgcaatg cttggtattg aaggtttact
     2881 tcttcacgaa gacggattgt ttcttcatcg atttctttga ttgcattcca gtcgtttact
     2941 ttttcttgca tcaagtagtc tgcaccgtaa agagcaagac gtgcgtaaac accgatgata
     3001 cgtccgcgtg agtatgcatc tggaagacca gttacagtgt gtgcatgacg agcgcgacga
     3061 atatttgaag tgtaggcacg gaaaataccg tcgttaactg ttgttacata tttagtgaag
     3121 atttcgtgaa cagctgggtc tggttcgtat ccattttctt ttaaagtagt ttcagccata
     3181 cggataccac cttttggcat gaagttcaat ttgaagagtt catcattttg gataccaaag
     3241 ataacttcat tttctttgtc gataaatcca gcagggatat cagcgataga tgttggacga
     3301 gtgtccattg ggaaacgagt ttcttcgtag tgtgctttag tttcttctac aattttcttg
     3361 atgtgaagtg aacgctctgt tggtcctgca aggaagcttt cgtctccatc ataaggtgtg
     3421 tagttagctt gtacaaagcg tgatacactt gctttttctt tccaatctac gcctttgaag
     3481 ccttcccaag ctttgtcaaa aatatcttgt gcttcaacaa ctgtcttaac aaccatatta
     3541 atgtcctctt ttttctagta acagtcatct gttacattca taagacaagt ataccataaa
     3601 gtaaccgatt tcaacaagtg caaaatccct atttttacac tttcttttct aaaacagtct
     3661 atattttatt tcaaactgta ttatattttt gaaaaaaata aagtcctttt ttcttttttt
     3721 cagaaaaaag ggtataataa aagaaaataa gcagtaacac tcaatggaaa tcgaaaagca
     3781 aactaggaag ctagccgcag gctgctcaaa acactgtttt gaggttgcag atagagctga
     3841 cgtggtttga agagattttc gaagagtata aaaaggtgct aggcatgttg atttttcctt
     3901 tgttaaatga tttgtcaaga aaaatcatcc atattgacat ggatgccttt tttgctgcag
     3961 tggaaatcag ggataatcct aaactcagag gaaaacctgt cattattgga agcgaccctc
     4021 ggcaaacagg tggacgggga gtcgtttcta cctgtagtta tgaggcaaga gcttttggtg
     4081 tccattctgc catgagttcc aaggaagctt atgaacgttg tccccaggcc gtctttatct
     4141 caggaaatta tgagaaatac aaagctgtgg gactccagat tcgagctatt tttaagcgct
     4201 atacagattt gattgaaccc atgagcattg acgaagccta tttggatgtg acagaaaata
     4261 aactcggtat caagtcagcg gtcaaaattg ctcgcctcat tcaaaaagat atctggcaag
     4321 aactccatct aactgcttct gccggtattt cctataacaa gttcttagct aaaatggcga
     4381 gtgattatca aaaacctcat ggtttgacag tgattctacc tgaacaggct gaggattttc
     4441 tcaaacaaat gaatatttcc aaatttcatg gagtaggaaa aaagacagta gaacgtcttc
     4501 atcaaatggg cgtttttact ggtgctgatt tacttgaagt tcctgaggta accctaatag
     4561 accgttttgg tagactaggc tatgatctgt atcgaaaggc tcgtggcatt cacaactctc
     4621 cagtcaaatc caatcgcatc cgtaaatcaa tcggcaagga gaaaacctac gggaagattc
     4681 tccgtgccga ggaagatatc aaaaaagagc tgactcttct atcagaaaaa gtcgctctca
     4741 atctacatca acaagaaaaa gctggaaaaa ttgtcatttt gaaaatccgc tacgaggact
     4801 tttcaactct taccaaacga aaaagtcttg ctcaaaaaac acaagatgct agtcagataa
     4861 gccaaatagc cctgcaactc tatgaagaat taagcgagaa agaaagaggt gtccgcctat
     4921 tggggattac catgactgga ttttaaagct caatgaaaat caaagagcaa actaggaagc
     4981 tagccgcagg ctgctcaaaa cactgttttg aggttgcaga taaagctgac gcggtttgaa
     5041 gagattttct aagagtataa aaccttgaag agttgcccct tcaaggtttt tcttatacaa
     5101 ataaacggac aaaactgtaa agtagcaaaa cactaccaag cacgatacgg tatttaccaa
     5161 aaagggtgaa gtcgtgtttt ttcacatagc tggtcaagaa gcgaatagcc accatactga
     5221 ccgcaaaagc tactcccatc gcgaccaaga gcaaaaacaa ttgcccaaag ctcaagagtt
     5281 ctcctgcttt tacaaatttg aaaatcttta aggcactagc tccaaacata acgggaatcc
     5341 caagatagaa ggtaaattct gtcacaactg aacgactggt tccatttaac aaaccaccga
     5401 caatcgttgc acctgaacgg ctagtccctg gtaaaagagc aagaacttgg aagagtccga
     5461 tatagaaagc ggtcgtataa ggaagcttgt ccaactctgt tacacttggc tcgatagcac
     5521 gcgctttatt gcgcttttcc aaatagatga aggcaacccc gtagataatc aacatgagag
     5581 caactgaaac catgttatgg aagtgggtat caaaccaatc atcaaattta aagacaccaa
     5641 gtaaaggcaa agtggcaatc aagaccttca accatagtct ccaagtctta cgaacttcct
     5701 gtttgtcctt agtcggttta aaaggattga gcttgttaaa ataaatcacc ataactgcta
     5761 aaatagcacc aagctgaatc acgacattaa acatggacat aaaggcttca ttttgatttt
     5821 ggtattggat aaactcctct gctaaaatca agtgacctgt actggaaatc ggcaaccatt
     5881 ccgtaattcc ttcaacaatc ccgaagaaga tagattttaa aatttcaata agatacatat
     5941 atttctcctt atattatatt taacgcagtt agctactgcc aaagcccaag tggtatactt
     6001 ggaataagcc actgtggatt agttcatttc ctccaatcgc ttgacgattt ccgaaagggt
     6061 ctaaccacag ctttttgttt caattggtaa tgagtttgat aacgcataga cgttttatct
     6121 cgtctaaggt aacaaggcaa aaagttcgtg gataaccaag tagacttgaa atactatatc
     6181 tggaggtact cccatgcttt atgtgggcat tgatgtcgct aaaaataaac acgatgttac
     6241 agccttgaat gttcgaggaa aactgttctt aaaccactca ctttttcaaa taataaagct
     6301 ggttttgaac tcttagatct gtcttttcga cagctcaacc aagactgtct catcgctctt
     6361 aaacttcttt ctgaccccaa tcgtgaacaa tttcaacacg ataatcggca agtagaccta
     6421 aaaatactgg ctagacatat tcatcgtctc aagagaaaac agtctgattg gaaagtacaa
     6481 tacactcgtt gtcttgatat catctttcct gagttggata aaatcgttgg aaagcattca
     6541 gaatatacct accaactctt gacacgctac cctaatcctc agaaaaggat tgaggcagga
     6601 tttgataagc tgatagaaat taagcgattg accgcttcta aaattcagga tatcctctca
     6661 gtcgcacctc gttctatcgg aacaacatct cctgctcgtg aattcgaaat catcaaacat
     6721 tacaagaggc tcattgacaa ggcggaaaca tgtgtcaatg acttgatggc tgagttcaac
     6781 tcggtcatca cgacggttac tgggattggg aatcgtttag gggcagtcat tttagccgag
     6841 attcgaaata ttcatgcctt tgatattcct gctcaattac aagctttcgc tggactagat
     6901 tcttctattt atcagtcagg tcagattgat ttagcaggaa gaatggtcaa acagggttcc
     6961 cctcatctgc ggtaggtact catacaagct gccaaagcat gccctcgctt ttcacctgct
     7021 tttaaggcct atcttaagac taagttagaa caaggaaaac attacaatgt agccatcatc
     7081 caccttgcaa aaaaacttat ccgaaccctg ttttatatcc taaaaaagag ctgccatttg
     7141 acgaacaaaa agtgatgtaa tttctgaaat taacacagga ttacctttga aaaaatggac
     7201 tttttcaaga gctttttgcc gtgctctaaa atcatcgcca aatcatcaaa ttgaaataag
     7261 aaatagttta gataaaacta ttgacttttc ttatagtttg tcttttttct atcttccatt
     7321 atatcatact ttttcagtct atggtagctc tctttaaaag gcaccgatac tgccgccacc
     7381 tccgcctcca gagaagccac caccagaact tccacttcca gaagatacag agtaggtgct
     7441 tgctgtattt gcgacactag cataatggct catttgtgct gttgaatgat aaaacatact
     7501 gtgccagcca taagctacat agagattgat atctggattt tcaacttgaa tctgatgaac
     7561 cttcatcaaa tgactaacct tgtccgcata gccaaataag gttgcataga ccaagagacg
     7621 attccaaaca acaatacttt ccaattcagc cttatccagt cgtgcaatct cacgtaacat
     7681 attttcaaaa ctggtccaga gatagtagac ctcagctccc gcttcattta gaacaccatc
     7741 acgattatct agtcgaagct tccaataata gaaaacagac aaaactaacc ctagaaaacc
     7801 aagtattggc aaagggaggt aaagatagcc atgaacgtct aaactgtaca agaacaaacc
     7861 aaatccgata aataagggca agatagtcaa gacacccata cccacttgca aagccttttc
     7921 caaaccagtt aaaggacgat agtaatctgg gagcccccag aaggaaactc gttttctcac
     7981 tccttcttgc atctggttca atacctcttc aaaagaagat ttgagttgaa gccctcttgc
     8041 ttgaatccgt ttttcatcag aaactttggc tctacgataa agactatcag ataccttgta
     8101 atccgcaaac aaattggaaa gagtttcttc ttttttacct gaaaaagcta gatttaggca
     8161 gtctttctca aagcttgaca aaccatcttc ttttactagc ctcaaaccaa ctgcatctcc
     8221 ttctgaaatg atagagacat tcccacggtc tatcacatct agcaaggtag cttgaataag
     8281 ttgatcaaag gtgaattttc cagctccctt gaccaaggga ctcacttcct ccaaggaggt
     8341 cgagtagact gcttctgata aaaccatagg ctctaattcc attgggggtt catagagacg
     8401 atgattttta gcatatttga ttgaaggagc ggtctttctt ctatagataa aatagaaaca
     8461 gatgctcaat aacaaggaga tggaaaggat cgaagggaag atccaagtaa gtagttgttt
     8521 actttgctct ttttctttaa cgatcgaatc ctctatctta ttaaactctt ctaaacgatt
     8581 ccctttcaag ccctgatccc tagcgctagc aaaatcagtt cgcggccagt aggcatgcaa
     8641 ttcaactcca cgcttagccg gaagattgtc taaacgaata gtataatcaa ggttactctt
     8701 ttcaaccgtt ctctctctaa aaagtttccc tgtatggaaa aagagtttct cagccccctt
     8761 gtctcccctt acatgaaatt caaacttttc aatagactct gaactatctg tcataggttg
     8821 ccaatttaat tcagcgatat catcataaag gaaaagtaaa ttttttaagt tccagacgag
     8881 gtcaacttca actatgtcgc cctcctgacc tggattatag actctcacag tataaccatc
     8941 cgcttcttct gttacttcgc tagtcacatc tgctagttct gcaccgtttt ttgcggcctg
     9001 aatctttgga tgagggtcaa tgtcaaaccc gctaggcatc ttaccagcac gtccaagtcc
     9061 cacgatttgg cccttaaagt cctcctcaaa ctggtaaact atcttctgtc taaactctgc
     9121 cgtattgtct gcatgaatat acaaatcccc ttgataagag tttatcttga aatcaatggc
     9181 aaaaacagag agtggaagaa ggcaaaacaa gcctaacacc agtaagaaaa aagttttttt
     9241 catcaactaa gccccctttt tatctttctt atcattatag cattttttcg taagtaaagg
     9301 cttacttatg ttgaaaaatt acgcattttt cgataaaata ggagacagtt attttttaat
     9361 agatcagaat aggagaaatc atgagaaaaa tatacttatc tattttcaca agtctcttgc
     9421 tgatgctagg acttgtcaat gttgctcaag ccgatgaata tttacgcatc ggtatggaag
     9481 cagcatatgc tccctttaac tggacccagg atgatgatag caacggagct gtcaaaatcg
     9541 atgggaccaa tcagtatgcc aacggatacg atgttcaaat cgccaagaaa atcgctaagg
     9601 acttaggtaa agaacctttg gttgttaaaa ccaagtggga aggtctagtc cctgccctta
     9661 cttctggtaa gattgacatg attatcgcag gtatgagtcc aactgcagaa cgcaaacaag
     9721 aaattgcctt ttcgagcagt tactatacta gcgaaccagt tttgcttgtc aaaaaagatt
     9781 ctgcctacgc aagtgctaaa tctttggatg actttaacgg tgcaaaaatc acttctcaac
     9841 aaggggtcta cctttatgac ttgattgcac aaatcccagg tgctaaaaaa gaaacagcca
     9901 tgggagactt cgctcaaatg cgacaagctc ttgaggctgg tgtcattgat gcttatgttt
     9961 ctgaacgtcc agaagcactg actgctgaag ctgcgaactc taagttcaag atgattcaag
    10021 tagaacctgg tttcaaaact ggggaagaag atacagctat cgctatcggg cttcgtaaaa
    10081 atgacaatcg tattagccaa atcaatgcca gcattgaaac catttcaaaa gatgaccaag
    10141 ttgccttgat ggatcgtatg atcaaggaac aacctgccga agctacaaca actgaagaga
    10201 ctagcagtag tttctttagc caagttgcta aaattctttc tgaaaactgg caacaactct
    10261 tgcgtggtgc tggtatcact cttttaatct ctatcgtcgg aaccatcata ggtctcatta
    10321 ttggacttgc cattggtgtc ttccgtactg ctcctctctc tgaaaacaaa gtcatttacg
    10381 gcctacaaaa actagtcggc tggggtctca atgtctacat tgaaattttc cgtggtacgc
    10441 caatgattgt tcaatcgatg gttatctact atggaactgc ccaagctttc gggatcaacc
    10501 ttgaccgtac actggctgct atcttcatcg tttcaatcaa taccggtgcc tacatgactg
    10561 aaatcgtccg tggtggtatc ctagcagttg acaagggaca atttgaagct gcgactgctc
    10621 ttggtatgac ccataaccag accatgcgta agattgtcct acctcaggta gtccgtaaca
    10681 tcctacctgc aactggtaat gaatttgtca tcaatatcaa agatacatct gtattgaacg
    10741 ttatctctgt tgtcgaactt tatttctcag gaaataccgt ggcaacacaa acctatcaat
    10801 acttccagac atttacaatc atcgccgtga tttactttgt cctcaccttc accgtaacac
    10861 gtatcctacg ctttatcgag cgcagaatgg acatggatac ctacactaca ggtgctaacc
    10921 aaatgcaaac ggaggatttg aaataatgac acaagcaatc cttgaaatta aacacctcaa
    10981 aaaatcctat ggacaaaacg aagtgctaaa agacatttca ctcactgtcc acaagggaga
    11041 ggtcatctct atcatcggaa gctctggaag cggaaaatcg accttcctac gctccattaa
    11101 cctacttgaa acaccaactg atggacaaat cctttatcat ggacaaaacg tcctcgaaaa
    11161 aggctatgac ctcacgcaat accgtgaaaa gttggggatg gttttccaat cctttaacct
    11221 ctttgaaaat ctcaatgttc ttgaaaacac aatcgtcgct cagacaactg tcctaaaacg
    11281 cgaacgcaca gaagctgaaa agattgccaa agaaaacctg gaaaaggtcg gcatgggaga
    11341 acgctactgg caagccagac caaaacaact ctcaggtggt caaaaacaac gtgtggccat
    11401 cgctcgtgcc ctctccatga atccggacgc tattctcttt gatgaaccaa catcagctct
    11461 cgatccagaa atggttggag aagtcctcaa aatcatgcag gacctggctc aggaaggctt
    11521 gaccatgatt gtcgtaaccc atgaaatgga atttgcccgt gatgtctctc accgtgttat
    11581 ctttatggat aagggcgtga tcgctgaaga aggtaaacca gaagacctct tctccaatcc
    11641 taaagaagac cgaacaaaag agttccttca acgctatctc aaataaaaag aaaaggctgc
    11701 atcaaccgtg cagtcttttt gctgtcctca aaatgaaaag gcagattctc tatctctact
    11761 acttgaaggt caagaatccg ccgttatcca aagattaatc ttcaaatttt tcataatttt
    11821 tttcatagaa atcaattagg cctagggctg tttcaaatga aatatttttt acttttgcac
    11881 gaccctgcgc cagagcaatg atagacattt cacgcgcatt cgtttcttta gagatacggt
    11941 agcctgtgat tttcttatca cgaacccagc caacaactga ttctactttt tcaaagtttg
    12001 acttagccat gtttttctcc tattttcttc t
//
LOCUS       DAVKMO010000054        11606 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVKMO010000054 DAVKMO010000000
VERSION     DAVKMO010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11606
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.054"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(114..830)
                     /locus_tag="VW361_001725"
     CDS             complement(114..830)
                     /locus_tag="VW361_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9744724.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            1178..2965
                     /locus_tag="VW361_001726"
     CDS             1178..2965
                     /locus_tag="VW361_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU9744725.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRNPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            2962..3438
                     /locus_tag="VW361_001727"
     CDS             2962..3438
                     /locus_tag="VW361_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9744726.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            3466..4371
                     /locus_tag="VW361_001728"
     CDS             3466..4371
                     /locus_tag="VW361_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9744727.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVAYGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            4358..5173
                     /locus_tag="VW361_001729"
     CDS             4358..5173
                     /locus_tag="VW361_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9744728.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFASLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            5180..5584
                     /locus_tag="VW361_001730"
     CDS             5180..5584
                     /locus_tag="VW361_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9744729.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIGGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            5878..7044
                     /locus_tag="VW361_001731"
     CDS             5878..7044
                     /locus_tag="VW361_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU9744730.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            7160..8197
                     /locus_tag="VW361_001732"
     CDS             7160..8197
                     /locus_tag="VW361_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU9744731.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            8403..9257
                     /locus_tag="VW361_001733"
     CDS             8403..9257
                     /locus_tag="VW361_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9744732.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     RGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            9407..9664
                     /locus_tag="VW361_001734"
     CDS             9407..9664
                     /locus_tag="VW361_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
                     /protein_id="HEU9744733.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQLLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(9832..10068)
                     /locus_tag="VW361_001735"
     CDS             complement(9832..10068)
                     /locus_tag="VW361_001735"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744734.1"
                     /translation="MKIKVQTRKLAAGCSKHCFKVVDRTDEVSSKHCFEVVDRTDEVS
                     NHIYGKVKLMWFEEIFEEYKSLHNKTHITKVLMN"
     gene            complement(10122..10418)
                     /locus_tag="VW361_001736"
     CDS             complement(10122..10418)
                     /locus_tag="VW361_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9744735.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
     gene            complement(10408..10569)
                     /locus_tag="VW361_001737"
     CDS             complement(10408..10569)
                     /locus_tag="VW361_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU9744736.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            10639..11403
                     /locus_tag="VW361_001738"
     CDS             10639..11403
                     /locus_tag="VW361_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU9744737.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
BASE COUNT         3250 a         2155 c         2639 g         3562 t
ORIGIN      
        1 ctataaaata ttccacaaat tatagaatct tccaaaaata ggtaagcgct acctttttgg
       61 tgtggtataa taagcataga aaaagcccga gcgattaggc tcaggctttc ttcttagtga
      121 tcacggtcac atgagatgaa tttaatcttg tagtaatcag atcgtttgta agtttcactg
      181 tattctaaaa cttggccagt tgattcgagt ttggtgattt tagtttgtag gacagtaggg
      241 aattgttcat cgactccgag gactgaagcc gcatgttctg gagttggaaa gactatttcg
      301 ttgatttctt caaagtgttc atcattcatg tgaatgtggt agtctaactt gaaacgatta
      361 tagatagaac tatagtattc aaggtttgga taatttgcgt tgatatattg ttctgggatg
      421 taggatgtat ggtagatata aacgacaccg tttgattcgc ggatacgttc aatcttgtag
      481 tagaattgat cgccacgtag acccaatttt tccaagtaaa caagcttgtt tccgcgttca
      541 attgaaagaa cagttacctt atcatcttta gcattgaaga gttcaatatc tgaaaactct
      601 acaagcttgt gtttgcgtgc acgtgaaacg aaggttcctt ttccttgttg gcggacaata
      661 tagccatctt tggcaaggtc gtttaaggcg cgaacaactg tgatagagct gacatcgtac
      721 attgaaatga gttctgcttc agtgtaaaat ttatctccac tgctaaactg cccagagatg
      781 attttatttt ttaattcgtc ttttatgtat tgatatttgg gaattgccat atttttacct
      841 ctattttcct tctccataga aaattttacc ataaaagcga aaaaaatagt agtcttttga
      901 ataaaaaatt agaataatag tttgaaaaat taagcgatat agggattgct catattttat
      961 caatgtattc tatacaaaat tattttatgt cctatattcc gaatttaaag agcgtttgaa
     1021 atgggtctaa aaatgtttga aactaattga atgtgtgtat aatagtaaaa atgcagtaaa
     1081 tatcccgaca atttctattg acaattcaaa cagattggtt tataattaat ataacaacaa
     1141 atgaaagcgc aaactttcgt ggtcggaagg tagttttatg acacgatttg agatacgaga
     1201 tgatttctat ctcgatggaa aatcatttaa gattttatct ggtgccattc attattttag
     1261 ggttcctcca gaggattggt atcattcgct ctataacttg aaggctcttg gttttaatac
     1321 ggtagagact tatgttgctt ggaatttaca cgagcctcgt gaaggtgagt ttcattttga
     1381 aggtgatctg gatttagaga aatttctcca aatagcgcag gatttgggtc tctacgcaat
     1441 tgtgcgtccg tctccattta tctgtgcgga atgggaattc ggtggcttac cagcttggct
     1501 cttgaccaag aacatgcgaa ttcgctcatc cgacccagca tatatcgagg cagttggtcg
     1561 ctactatgat cagttattgc caagactggt gcctcgtttg ttggacaatg gtggcaatat
     1621 tctcatgatg caggttgaaa atgagtatgg ttcttacgga gaagataagg cttacctgag
     1681 agcgattcga cagctaatgg aagagtgtgg cgtaacctgt cccctcttta catcagatgg
     1741 tccgtggcga gctactctga aagctggaac cttaattgaa gaggacctct ttgtaacagg
     1801 aaactttggt tctaaggcac cttacaactt ttcgcagatg caggaattct ttgatgaaca
     1861 tggtaagaaa tggccactca tgtgtatgga gttctgggat ggttggttca atcgctggaa
     1921 agaaccgatt atcacacgga atcctaagga attggcagat gcagttcgag aggttttgga
     1981 acaaggctct atcaatcttt acatgttcca cggtggtaca aactttggtt tcatgaatgg
     2041 ttgctcagct cgaggaactt tggacctgcc acaagttacg tcttatgatt acgatgccct
     2101 tctggatgaa gaaggaaatc caactgctaa atatcttgca gtcaagaaga tgatggcaac
     2161 acatttttca gagtatccgc agttggaacc actctacaaa gagagtatgg agttggatgc
     2221 tattccacta gttgaaaaag tttctttgtt tgaaacctta gatagcttgt caagtcctgt
     2281 agaaagtctc tatcctcaaa agatggagga gctgggacaa agttatggct acctacttta
     2341 tcgaacagaa acaaactggg atgcagaaga agaaagactt cgtatcattg atggtcgaga
     2401 tagggcccag ctgtatgtcg atggtcagtg ggttaaaact caatatcaga cagagattgg
     2461 ggaagatatt ttttatcaag gtaaaaagaa agggctatct aggttagata tcttgataga
     2521 aaatatgggg cgtgtcaact atgggcataa gttcttagcg gatacgcaac gtaagggaat
     2581 tcggacaggg gtctgtaagg atctgcattt cttactaaac tggaaacact atccactccc
     2641 actagacaat cctgagaaaa ttgatttttc aaaaggatgg actcaaggac aaccagcctt
     2701 ttacgcttat gactttacag tcgaagagcc aaaagatact tacctagact tgtctgagtt
     2761 tggtaagggg gttgcctttg tcaatgggca gaatctagga cgtttttgga acgttggccc
     2821 aactctctca ctttatatcc ctcatagcta tctcaaggaa ggtgccaacc gcatcattat
     2881 ctttgaaaca gaaggtcaat ataaagaaga gattcattta actcgtaaac ctacactaaa
     2941 acatataaag ggggaaaact tatgacaatt gtaggatgcc gtattgatgg acgtttgatc
     3001 cacggacaag tagccaatct ttgggctgga aaactaaatg tttcacgcat tatggttgta
     3061 gacgacgaag ttgtcaacaa cgatattgaa aagagtggtt tgaaacttgc gacaccacca
     3121 ggtgtgaaat tgagtatttt gccagttgag aaagctgcag ccaatattct tgctggcaaa
     3181 tacgatagcc aacgtctctt tatcgtggct cgtaaaccag accgcttcct tggtttggta
     3241 gaagcaggtg taccacttga aacccttaat gttgggaata tgtctcaaac accagaaact
     3301 cgttctatta cacgttctat caacgtagta gacaaggatg tggaagactt ccacaaactg
     3361 gcagaaaaag gtgttaaact tactgctcag atggttccaa atgatccaat ttcagacttt
     3421 ttgagcttat taaaatagga aaaaaatttt taggaggtca ttgttatgat acaatggtgg
     3481 caaattttac ttctcacttt gtactcagct tatcaaatct gtgatgagtt gacgatcgtt
     3541 tcatctgcag gttcccctgt atttgctggt ttcattactg gtttaatcat gggagatgtg
     3601 actactggtt tacttatcgg tggtaacttg caactgttcg ttcttggggt tggtaccttc
     3661 ggtggtgctt ctcgtatcga cgcaacttct ggtgcggttc ttgcgacagc cttctctgtt
     3721 tcacaaggaa ttgatgcacc gcttgccatt actacaatcg ctgtaccagt agcagctctc
     3781 ttgacttact tcgacgttct tggtcgtatg actactacct tcttcgctca ccgtgtggat
     3841 gctgcaatcg aacgctttga ctataaaggt attgaacgca actacttgct tggtgcgatt
     3901 ccgtgggctc tatctcgtgc ccttccagtc ttctttgccc ttgcttttgg tggtgccttt
     3961 gtacaatcag tagtagactt cgttgaagcc tacaaatggg ttgcatatgg cttgacactt
     4021 gcaggacgta tgcttccagg tcttggattt gcaatcttgc ttcgttacct tccagttaaa
     4081 cgtaaccttc actaccttgc tatgggattt ggtttgacag ctatgttgac tgttctttac
     4141 tcatatgtaa caggtcttgg tggcgctgtt gctggtatcg taggtactct tcctgctgaa
     4201 gttgctgaaa aaattggttt cgtgaacaac ttcaaaggtt tgtctatgat tggtatttct
     4261 atcgtaggta ttttccttgc agtgcttcac ttcaaaaata gccaaaaagt agctgtagca
     4321 gcaccttcta caccatcaga aagtggggaa atcgaagatg acgaattcta attacaaact
     4381 tacaaaagaa gattttaatc aaatcaacaa acgtagcttg tttactttcc aattaggttg
     4441 gaactacgaa cgtatgcaag cttctggtta cctttacatg atcttgcctc agttgcgtaa
     4501 aatgtatggt gatggaactc ctgaattgaa agaaatgatg aaagttcata ctcaattctt
     4561 caatacttca ccattcttcc ataccattat cgctggtttt gaccttgcca tggaagaaaa
     4621 agatggtgta ggttcaaaag acgccgttaa cggtatcaag acaggtttga tgggaccatt
     4681 cgctcctctt ggggatacaa tctttgcttc acttgtacct gctatcatgg ggtcagtcgc
     4741 agcaactatg gctatcgctg gccaaccttg ggggatcttc ctttggattg cagttgcagt
     4801 agcgtatgac atcttccgtt ggaaacagtt ggaatttgct tacaaagaag gggttaacct
     4861 tatcaacaac atgcaaagta ccttgacagc tttgattgac gctgcatctg tacttggtgt
     4921 cttcatgatg ggtgctcttg tagcaacagt gattaacttt gaaatttctt acaagttgcc
     4981 aatcggtgaa aagatgattg atttccaaga catcttgaat caaatcttcc cacgtttgct
     5041 tccagcaatc tttactgcct ttatcttctg gttgcttggt aagaaaggta tgaactctac
     5101 taaagctatc ggtattatta tcgtacttgc tttggctctt tctgcccttg gtcactttgc
     5161 acttggaatg taattcctta tgactaaatc attaattttg gtgagccatg gtcgcttctg
     5221 tgaggagctt agaggtagca cagaaatgat tatgggccca caagacaaca tttacacagt
     5281 agctcttctt ccagaagatg gcccagaaga atttactgct aaatttgaag ctgttattgg
     5341 aggattggat gatttcctag tctttgcgga tcttctcggt gggacacctt gtaatgtggt
     5401 gagtcgcttg atcatggaag gtcgtgatat tgacctttac gcagggatga atcttccaat
     5461 ggtgattgaa tttatcaatg cgagccttac aggcgcagat gcggactaca agagccgtgc
     5521 tgcagaaagc attgtgaaag ttaatgacct gttagcgggc ttcgatgatg acgaagatga
     5581 ataatactct tcgaaaatct cttcaaacta cgtcaacgtc gccttgccgt aggtatatgt
     5641 tactgacttc gtcagtctta tccggcaacc tcaaaacggt gttttgagct gacttcgtca
     5701 gttctatctg caacctcaaa gcagtgcttt gagcagcctg cggctagttt cctattttag
     5761 ttggaactcg attcaattca tgtgacaacg tgaaaatcgt tagagcattt tatatagaat
     5821 atacatggga atggagctta ctcccattcc catatttaat agaaaaagag gaactcaatg
     5881 ctacattata caaaagaaga cttgctcgaa ttgggtgcag aaatcactac gcgtgaaatc
     5941 taccaacagc ctgatgtatg gagagaagct tttgaatttt atcaagcaaa acgtgaagaa
     6001 attgcagcct tcctacaaga aatcgctgat aaacatgact atattaaggt tatcttgaca
     6061 ggtgctggga cttctgctta tgtgggagat accttgctac cttactttaa ggaagtctat
     6121 gacgaacgca aatggaattt caatgctatt gcgacaacag atatcgttgc caatccagca
     6181 acctatttga aaaaagatgt ggcaactgtc cttgtgtctt ttgctcgtag tgggaactcg
     6241 cctgaaagtg tggcgactgt tgatttggcc aaatccttgg tggatgagct ttatcaagtg
     6301 acgattactt gtgcagcaga tggtaaattg gctcttcaag ctcacggtga tgaccgtaat
     6361 ctcttgctct tgcaaccagc tgtctctaat gatgctggat ttgccatgac ttctagcttt
     6421 acgtctatga tgttgacagc tctcttggtc tttgatccta cagaatttgc tgttaagtct
     6481 gaacgttttg aagttgtatc tagtcttgcc cgtaaagttt tagacaaggc agaagatgtc
     6541 aaagagctcg ttgatttaga ctttaaccgt gtcatctatc taggcgctgg tcctttcttt
     6601 ggacttgctc atgaagctca gctcaagatt ttggaattaa ctgctggtca agttgcgacc
     6661 atgtatgaaa gcccagttgg cttccgtcac ggtccaaaat ctcttatcaa cgacaataca
     6721 gttgttttgg tctttggtac aacgacggac tacactcgta agtacgactt ggacttggtt
     6781 cgtgaagttg ctggtgacca gattgctcgt cgtgttgtgc ttttgagtga tcaagctttt
     6841 ggtcttgaaa atgtcaaaga agtggccctt ggttgtggcg gtgtcttgaa tgatatttac
     6901 cgtgtcttcc cttacatcgt ttatgcccaa ctctttgccc tattgacttc actcaaggta
     6961 gaaaataaac cagatacacc gtctcctaca ggtacagtaa accgtgtagt acaaggtgtc
     7021 ataattcacg aatatcaaaa gtaagacagt gtttatgaat tcttgacaag aggatttgta
     7081 aattatcaga taaaccatag attgtcagta cgctttctat ggtttgtttg cttgagagaa
     7141 atagtaaaag gagaacagaa tgaaagcata cacagagcgt gtatttggaa atgttgaggg
     7201 tgaggatgtc ttggcctatc gatttgagac agacggtggc taccaacttg aggttatgac
     7261 ttatggtgcg actatcttgc gctatgtcgc acctgacaag gctggaaatt ttgccaatgt
     7321 tatcttggga tttgatgact ttgatagtta tgtaggcaat agtcccaagc atggagcaag
     7381 tgtaggtcct gtagcgggtc gtattgcagg tgcgaccttt gagctcaatg gtaagaccta
     7441 tgaccttgag gttaataatg ctagcaactg taatcacagt ggttcaactg gttgggattc
     7501 cagcttgttt gaagttgaag aagtaagcga tcatggcttg actctctaca cagagcgtac
     7561 agatgggaca ggagggttcc ctggaaatct caagatttgg atcagttatc acttggaaga
     7621 aactggtgcc tatgaaatca gctacaaggt aacgaccgat caggatacgc tggtcaatcc
     7681 aaccaaccac agctatttca acttgtctgg tgatttcacg cagacgattg accgtcatgt
     7741 cttccaacta aacacagagg gcatttactc aatcgctcct gacggtgttc ctgccaaaac
     7801 tccagaagcc aaccgtgatg tggtcaaaca catctacaat ggtgccttgt tgaaggatat
     7861 ctttgcagaa gaagatgagc aaatccagct ggcatcaggt ttggatcatc catttgccct
     7921 tcctgcaggc catgacaatg ctggattcct ttatgaccaa aattcaggtc gcttcctgct
     7981 tttcaagaca gaagctcctt gctttgtggt ctacacagca aactttgtgg atgaaagtgt
     8041 catcatagga ggtcagccaa tgctacagca caatgggatt gctcttgaag cgcaagcttt
     8101 accagatgcc attcacagtg accttaaagg ccaagtcatt cttaaagctg gtcaaacctt
     8161 caccagtaag acacgttatg aacttgttgt gaaataaaaa agctggtcaa aaagtcttta
     8221 aattaaaata acgcatattg tcaggtgatg aaaagtttga taatatgcgt tttattatga
     8281 aatgatttac tttatcttat cctgaaatgg tgttattttt gagttatctg gcttgacttt
     8341 cttgatggaa attatataat agttgtaata acaataatta caacgagaaa agaggaccat
     8401 ttatgaccta tgaatacaag agtcacattt atttggcaga gacagtttta aatgtaaagg
     8461 atttggccag tcaaacagcc ttttatcagc aagttattgg tttagaaatc ttatctcaaa
     8521 ctgagacaga gtccattcta ggccttggtg gaaaagtctt ggtacagctg attcaagcac
     8581 aagagagcgg agaagtgagg gaacattatg gtctttacca tttggccatt ctcttgccca
     8641 cacgcaaggc tttggctgat gtcttgaaac atctgacaga tttgcaaatt cctcttgtcg
     8701 gcggtgcaga ccatggttac agtgaagcta tttacttgga agatttggag ggaaatggca
     8761 ttgaactcta tcgagataag ccagtttcca catgggatat tcgagaagat ggacgcatta
     8821 tcggagtgac ggaggctctt gcggcgcagg acatttatga gttgggggaa agagtagagc
     8881 cctttatcct ggcagaaggt acaagaatgg ggcatattca tctttccgtc aaggatagtc
     8941 gaaagtccag ccagttttat caaaaggtgt tagggctaga gaataaattc agtgtgcctg
     9001 gcgctagttg gattgcggct ggagattacc atcatcattt agcagttaac gaatggagag
     9061 gaaaaggtct ggcttcgcgt aagcaaggct taccaggttt agcctactat gtcatcgaag
     9121 ttgcacataa aaaagaactg ttaacgattg cccaacgagc acaagaagtt gacgcaccaa
     9181 tcaaatggat gacatcgagc aaattggaaa tcacagactc agatggcatc gtgacccgta
     9241 ttcgtttagc aaggtaaaat taggaatttt taataagtta taagtattgc tagtttgctt
     9301 tttgaacggt ctttggtaac agaactgcgt gagctggatg agtgagaatt ttgacaaaga
     9361 agctgattag agatataatg aagaaaaatc gagcaaggaa aaagaaatga caaattcaaa
     9421 gtatattact tgtttgaaac gttcagaggg ccagttgtgt gggattcaaa agatgattga
     9481 aggagatcgt gactgtgctg atattgtgac gcaactgaca gcagtgagat ctagtgtaga
     9541 gcgcgtgatt gagatgataa ttaccgaaaa tcttactgaa tgtatcaatc agctactaga
     9601 tgattctgaa gctcaaaagg aacgcctaga aaaggctatc cgatacttga ttaaacggaa
     9661 ataaatgaat gttttgagac gatatgtgca aaggtctatt aactattaga atagtttaat
     9721 gtgagtcaaa agaagttgta aaaaatcttt aaaattaaaa aaacgcatag tatcaggtgt
     9781 tgaatgtact gacccccaaa agttagattt tttctgtcta acttttgggg gtcagttcat
     9841 aagaaccttg gtaatatgcg ttttattatg tagagactta tactcttcga aaatctcttc
     9901 aaaccacatc agcttcacct tgccgtagat atggttactg acttcgtcag ttctatccac
     9961 aacctcaaaa cagtgttttg agctgacttc gtcagttcta tccacaacct taaaacagtg
    10021 ttttgagcag cctgcggcta acttcctagt ttgcactttg attttcattg agtattactt
    10081 catcttttcc tgaaattgag tttttgccca gctcctcttg attattctac ttgaccgggc
    10141 caagcattca taccaccttc tacgttggta acggtgaggc cttgggagct gagaaattgg
    10201 caggtagatg cagagcggac tcctccttga caaatgacat agtattcatg gtcaggtttg
    10261 agttctttgt agccttgctc taaggtactt aatggaagat ttttggcacc tggtgcatgt
    10321 cctgcttgga attcatgtgc ttcacggaca tcgataagtt ctagattttc attttggtat
    10381 tttccataaa agtcagccat gctgatacta gtttccatat tctactcctt ctgggttaac
    10441 cattttgtat agtgaataag cgccgtcaag gttttgggcg gtaaatcctg cttgcttgag
    10501 gataggctct gcgatatagc tgcgcaaacc actgtggcag ctgacgatgt aggcttgttt
    10561 tttgtccagt tcatcagctt cctccttgac actttgtcag tttttgatac aatagtacaa
    10621 aattagagga ggcaggctat gattcagaaa catgcgattc ctattttaga gtttgatgac
    10681 aatcctcagg cggttatcat gcccaatcac gaggggctgg acttgcagtt gccaaagaag
    10741 tgtgtttatg catttttagg tgaggagatt gaccgctatg caagggaagt aggggcgaac
    10801 tgtgttggcg aattcgtttc tgctaccaag acctatccag tctatgttat caactacaag
    10861 ggtgaggagg tctgtctggc tcaggctcct gttggctccg ctccagcagc ccagtttatg
    10921 gattggttga ttggctatgg tgtggagcag attatctcta ctgggacctg tggtgtccta
    10981 gctgatatag aggaaaatgc ctttctagtc cctgttcgcg ctttgcgaga tgagggagcc
    11041 agttaccact atgtggcacc ttctcgttat atggaaatgc agccagaggc tattgctgct
    11101 attgaggaag ttttggaaga cagagggatt ccttatgaag aagtcatgac ctggacgaca
    11161 gacggttttt accgagaaac ggctgaaaag gtggcttatc gtaaggaaga aggctgtgct
    11221 gttgtggaga tggagtgttc tgctcttgcg gcagtagctc aattgcgtgg ggttctctgg
    11281 ggtgaattgt tgttcacagc agattctcta gcggacttgg accagtacga cagtcgtgac
    11341 tggggctcgg aagcttttaa taaggcgcta gaactgagtt tagcaagtgt tcaccacctt
    11401 tagttgtact ggcaaaggat ttgttttatc ataaaatgtc tagctcatac ttttcaaaaa
    11461 tatgtttaaa cgaggtcacc ttcctcttgt cctaggcatg ttgaggttgg gaaaaatctt
    11521 taaaatcaga aaaacgtatc atatcaggtg ataaaaactt tgatactatg cgttttatgt
    11581 tggtaagatt tagagtgaga tgaaat
//
LOCUS       DAVKMO010000055        11499 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVKMO010000055 DAVKMO010000000
VERSION     DAVKMO010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.055"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            189..866
                     /locus_tag="VW361_001739"
     CDS             189..866
                     /locus_tag="VW361_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU9744738.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQVKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVETGEM
                     ELSARDTRFGPFLSREISPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            853..1650
                     /locus_tag="VW361_001740"
     CDS             853..1650
                     /locus_tag="VW361_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU9744739.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            1667..2770
                     /locus_tag="VW361_001741"
     CDS             1667..2770
                     /locus_tag="VW361_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU9744740.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGHLLVTRL
                     LEASQVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            3026..4045
                     /gene="galE"
                     /locus_tag="VW361_001742"
     CDS             3026..4045
                     /gene="galE"
                     /locus_tag="VW361_001742"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9744741.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEELTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPYTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            4047..5000
                     /locus_tag="VW361_001743"
     CDS             4047..5000
                     /locus_tag="VW361_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9744742.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(5062..5268)
                     /locus_tag="VW361_001744"
     CDS             complement(5062..5268)
                     /locus_tag="VW361_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU9744743.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            5320..5796
                     /locus_tag="VW361_001745"
     CDS             5320..5796
                     /locus_tag="VW361_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU9744744.1"
                     /translation="MAKEPWQEDIYDQEESRAERRPRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EGAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            5805..6476
                     /locus_tag="VW361_001746"
     CDS             5805..6476
                     /locus_tag="VW361_001746"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU9744745.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHSISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVRKKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            6607..6945
                     /locus_tag="VW361_001747"
     CDS             6607..6945
                     /locus_tag="VW361_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU9744746.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            6948..7577
                     /locus_tag="VW361_001748"
     CDS             6948..7577
                     /locus_tag="VW361_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU9744747.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            7817..8968
                     /locus_tag="VW361_001749"
     CDS             7817..8968
                     /locus_tag="VW361_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9744748.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            9286..10035
                     /gene="truA"
                     /locus_tag="VW361_001750"
     CDS             9286..10035
                     /gene="truA"
                     /locus_tag="VW361_001750"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU9744749.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQVI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            10025..10798
                     /locus_tag="VW361_001751"
     CDS             10025..10798
                     /locus_tag="VW361_001751"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9744750.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNDLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVSVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            10776..11237
                     /locus_tag="VW361_001752"
     CDS             10776..11237
                     /locus_tag="VW361_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9744751.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMIGMIVGFILSQSIKKIK"
BASE COUNT         3253 a         2159 c         2659 g         3428 t
ORIGIN      
        1 tttctgaata aactgtttat tttttatttt ttgatatttt tgcaaattgt ttaaaatctt
       61 tcaattggat tcacttatta ctttaggaca ttgaaacttc tttcgccaga ggtgcttata
      121 ttactgggaa gttgaagatt gaaatgtggt ataataagag gtaatagagt tttggaaagt
      181 gagagaagat gatttcaaag agattagaat tggtagcttc ctttgtgtca cagggggcta
      241 ttttactaga tgtgggaagt gaccatgctt atctgcctat cgagttggtt gagagaggcc
      301 aagtcaaaag cgctattgca ggtgaggtgg tggaaggtcc ctatcagtct gcggttaaaa
      361 atgttgaggc tcacggccta aaggagaaaa tccaagtccg tttagccaat ggcttggcag
      421 cttttgaaga gactgaccaa gtgtctgtca ttaccattgc tggcatgggt ggtcgtttga
      481 ttgctaggat tttagaagaa ggtttgggta agttagctaa tgtagagcgt ttgatcctcc
      541 agcccaataa tcgtgaagac gacttgcgta tctggctaca ggatcatgga ttccagattg
      601 tagcagaaag catcttagaa gaagctggaa agttttatga gattctagta gtggaaactg
      661 gagaaatgga attatcagca agagataccc ggtttggccc cttcttgtca agggaaatca
      721 gcccagtatt tgtccaaaaa tggcaaaaag aagctgagaa gctagagttt gccctcggac
      781 aaatcccaga aaaaaatctg gaagaacgtc aagttctagt agataagatt caagctatca
      841 aggaggtgct ccatgttagc aagtgaagtg atccaagctt atgaagcctt ttgccctcag
      901 gaattttcta tggagggaga cagccgtggt ctgcaaattg gcactttaga caagggtatc
      961 caaagggtca tggttgccct cgatattcgt gaagagacag tggcagaggc cattgaaaag
     1021 ggtgtggact tgattatcgt caagcacgcg cctatctttc gtcctatcaa ggacttgctt
     1081 gccagccgtc cgcaaaatca gatttacatc gacctgatta agcatgacat cgcagtttat
     1141 gtcagccata ccaatattga tatcgttgaa aatgggctca atgactggtt ttgtcagatg
     1201 ctaggaatcg aggagacgac ttatctgcag gaaacaggtc cagaacgtgg aattggacgt
     1261 attgggaata ttcagcctca gacattttgg gaattggccc aacaggtcaa gcaagtcttt
     1321 gacctagata gccttcgaat ggtgcattat caagagaatg atttgcagaa gcctatttca
     1381 agagtagcaa tttgtggtgg aagcgggcag tctttctata aggatgcttt ggcaaagggg
     1441 gcagatgtct atatcactgg tgatatctac taccatactg ctcaggatat gctgtctgat
     1501 ggcttgttag cattggatcc aggtcactat atcgaagtgc tttttgtgga aaaaatcgca
     1561 gcactcctta ctcaatggaa agagaaaaaa ggctgggaac tagagatttt acctagtcaa
     1621 gcatcgacca atcctttccg tcatatctag ttagaaagtg aagacaatga aaaaagttgc
     1681 cattattgga gcaggaattg tgggagcaac agctgcctac tacctctcga gagaaagtga
     1741 cctagaggtg accgtttttg accatgagca aggtcaagcc accaaggctg cagcaggaat
     1801 tatcagtcct tggttttcca aacgccgtaa taaagcctgg tacaagatgg cgcgcttggg
     1861 ggctgatttt tatgtggatt tattagctga tttagagaaa tcaggacaaa aaatcgactt
     1921 ttaccagcgt tcgggagtct ttctcttgaa aaaggatgaa tctaagttgg aagaacttta
     1981 tcaactggcc ctccagcgca gagaagaatc tcccttgata gggcaattag ccattctgga
     2041 ccaagcctca gctaatgaat tattccctgg tttgcaggga tttgaccgcc tgctctatgc
     2101 ttctggtgga gcgagagtag atggccacct cttagtgact cgtttgctgg aagccagtca
     2161 ggtcaagctg gtcaaagaaa aagtgactct gacaccgtta gcatcaggct accagattgg
     2221 tgaagaggag tttgagcagg ttattttggc gacgggagct tggttggggg acatgttaga
     2281 acccttgggt tatgaagtag atgttcgtcc tcaaaaagga caactacgag attatcagct
     2341 ggtccaagac atggaagctt accctgttgt catgccagaa ggggagtggg atttgattcc
     2401 ttttgcaggt gggaaattgt ccttaggcgc tacccacgaa aatgacatgg gatttgattt
     2461 gacggtagat gaaaccttgc tccaacaaat ggaggaggcc accttgactc actatctgat
     2521 tttggctgaa gctacttcaa aatctgagcg tgttggaatc cgtgcctaca ccagtgattt
     2581 ctctcctttc tttgggcagg tgcctgactt aactggtgtc tatgcagcca gtggactagg
     2641 ttcatcaggc ctcacaactg gtcctattat tggttaccat ttagctcaac tgatccaaga
     2701 caaggagttg accttggacc ctgaaaacta cccaattgaa aactatgtca aacgagtaaa
     2761 aagcgaataa tactcaatga aaatcaaaga acaaactagg aaactagccg cgggttactc
     2821 aaagcgctgc tttgaggttg tggatagaac tgacgaagtc agtaaccata cccatggcaa
     2881 ggcgacgttg acgtggtttg aattggattt tcgaagagta taagcatttt actgaaattt
     2941 tatcaggtag tttaggatgg caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa
     3001 ataatctgag aatcgaggaa aaaagatgca agaaaagatt ttggtaactg gtggtgccgg
     3061 ttttattgga acccacactg ttattgaatt gatccaagca ggccatcaag ttgttgtggt
     3121 ggataatctt gtcaatagca atcgtaagag tttagaagtt gttgaaagaa tcacaggagt
     3181 tgagattcct ttctatgagg cagatattcg tgacacagat accctcagag atattttcaa
     3241 gcaggaagaa ctgactggtg tcattcactt tgctggtttg aaggctgttg gcgaatcaac
     3301 acgtatccct cttgcctact atgacaacaa tatcgctgga actgtcagcc ttttgaaagc
     3361 catggaagaa aacaactgta aaaacatcat cttcagttct tctgcgacag tttacgggga
     3421 tccgtacaca gtgcccatct tggaagattt cccactttca gtgaccaacc catacggtcg
     3481 taccaagctc atgctagagg aaattttgac cgatatttac aaagcagact cagaatggaa
     3541 tgttgtcttg cttcgttact ttaacccaat cggagcccat gagagtggtg atttgggaga
     3601 aaatccaaac ggtattccaa acaatctctt gccatatgtg actcaagtag ccgttggaaa
     3661 attagagcaa gtgcaagtgt ttggagacga ttacgatacg gaagatggaa caggtgttcg
     3721 tgactatatc cacgttgtcg atttggctaa gggtcacgtt gcagctttga aaaaaatcca
     3781 aaaaggttca ggactaaacg tttataacct tggaactggt aaaggttact cagttcttga
     3841 aattatccaa aacatggaaa aagcggtggg acgtcctatt ccttaccgca tcgtagaacg
     3901 tcgcccaggt gatatcgctg cctgctactc agacccggca aaagctaaag cagaactcgg
     3961 ttgggaagca gaactcgaca tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa
     4021 gcatccaaat ggatttgaag actaagatga tgatttcaat catcgtccct tgtttaaatg
     4081 aagaggaagt acttcctctt ttttatcagg ctctggaagc tttacttcca gatttggaaa
     4141 cagaaatcga gtatgtcttt gtcgatgatg gatcaagtga tgggaccttg gaactcttaa
     4201 aggcctatcg ggagcaaaat ccggcagtcc attatatttc tttctctcga aattttggca
     4261 aagaagcagc cctttatgca ggcttgcaat atgcgacagg agatttggtg gtggtgatgg
     4321 atgcagacct ccaagatcct cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa
     4381 atgtagactt ggactgcgtt gggacacgga gaactagtcg ggagggagaa cccttctttc
     4441 gcagtttctg tgctgttctc ttttatcgcc tcatgcaaaa aatcagccca gtagctctgc
     4501 cgtcgggtgt ccgtgacttt cgtatgatga gaaggtctgt ggtcgatgcc attttaagct
     4561 tgactgagtc caatcgtttt tctaagggac tctttgcctg ggtcggcttt aaaacccact
     4621 atctggacta tccaaatgtc gaaaggcagg ctggcaagac cagttggagt tttaggcaac
     4681 tcttttttta ctccattgaa gggattgtta atttttcaga tttccctttg actatagcct
     4741 ttgtagctgg tctcctatct tgttttcttt ctctgctgat gacctttttt gttgtggttc
     4801 ggaccctcat tttgggcaat ccgacatctg gttggacctc tctgatggct gttattctct
     4861 ttcttggagg cattcaactc ttgaccattg ggattctcgg caagtatatc agtaagattt
     4921 atttagagac taaaaaaaga ccactttatc ttatcaaaga aaaaagtgac cttcctgatt
     4981 ttacagaaaa aataaagtga aaagactata attttacatg gaaatgtgct aaactagagg
     5041 gagtggatta tcgccattga tttaggcttc ctggtttcca atcagggcgc gagttgggca
     5101 atttttaaca gcctctaaga catcctgact aggagaaatt tctttttcca gttggtcagg
     5161 gtcatcgtaa aaacgcacga ttccattatc atggtaatca aataaatcag aataagtttg
     5221 gcaaagccca caggcgatac atcgttcagg tataagtgtg attttcatgt tcatatttat
     5281 attgtaataa gaaaagtaaa aaaaaacaag gagtaaggta tggcaaaaga accgtggcaa
     5341 gaagatatct atgatcaaga agaatcaaga gcagagcgtc ggcctcgaaa ccacggaggg
     5401 gctgatagga tggctaatcg tattttgacg atcctagcta gtattttctt tgtaattgtg
     5461 gtggtgatgg tcatcgttct catctatcta tcatcggggg ggagtaatcg cacagcagcc
     5521 ttaaaagact ttcatgattc tgatgcaagt gtagtacaaa tctcatcttc aagcagttct
     5581 cagcctgagc agagttcaga gccagaatct acttctagta gttcagaagg agctgctaat
     5641 cctgaaggaa ctattaaagt tctcgcagga gaaggggaag cagctattgc cgctcgtgca
     5701 ggaatctcca ttgctcagtt agaggccttg aatcctgggc acatggctac aggatcttgg
     5761 tttgctaatc caggtgatgt tataaaaata aaataggagc cgatatgaaa acaattcaaa
     5821 ttgctattga tggtcctgct tccagcggta agagtacggt cgcaaagatt attgctaagg
     5881 attttggatt cacctacctt gatacaggag ctatgtatcg tgcagcgacc tatatggctc
     5941 ttaagaacca attaggagtt gaagaagtcg aagcccttct agccttgttg gaccagcatt
     6001 caatcagctt tggacgttca gaaactggag accagcttgt ttttgtagga gatgtggata
     6061 ttacccatcc tatccgtgaa aatgaagtga ccaatcatgt ttctgctatt gcagcaattc
     6121 ctgaagtgcg taagaaattg gtttctctcc aacaagaaat tgcccagcaa ggcgggattg
     6181 tcatggatgg tcgcgatatt ggaactgttg tattgccaca agcagaattg aaaattttcc
     6241 tagtagcttc tgttgatgag agagcagagc gtcgttacaa ggaaaatatt gccaagggaa
     6301 ttgaaacaga ccttgaaacc ctaaaaaagg aaattgctgc gcgtgactac aaggatagtc
     6361 atcgtgagac ttctcctctc aaacaagcag aggatgctgt ctaccttgat acaactggtt
     6421 tgaacattca agaagtagtt gaaaaaatca aagcagaagc tgaaaaaaga atgtaaatgt
     6481 agaaaagccg atagattgat atcggttttt ttctaaattt gtcaaaatgc tgattttagg
     6541 gtataatagt tgctgttcga gaaattttga ttttcaaaga atagtgaatg atgataagga
     6601 gaaatcatga acaatttacc aaattgtcca aaatgtaact cagagtatgt ctacgaagac
     6661 ggtgccctac tggtttgccc agagtgtgct catgagtgga atcctgctga agttgcagaa
     6721 gtagaagaag gtcttgtcgc tatcgatgcc aacggaaata aattggctga tggtgataca
     6781 gtaactctca tcaaggactt gaaagtaaaa ggtgcgccaa aagatttgaa acaagggacg
     6841 cgcgtgaaaa atatccgcat cgtagaaggc gaccacaata tcgactgtaa gattgatggt
     6901 tttggtgcca tgaaactcaa atcagagttt gtgaggaaga tttaagcatg tcaaaacact
     6961 ataaacttgt attttatagc cgtatcttct tgtttctagc ggcttttacg ggagtttatc
     7021 ttgaaattac taagcatggt ggttttggga tgcttctcta ttacacggtt ctgtccaacc
     7081 tcttggtaac tatttttacc ctttatcttc taaaggttat gagccgtgta ggtgaaaatt
     7141 ggcaaaggcc aagtctcttg cgcttaaaag gtggggtcac catgagtatc atgattacct
     7201 gtgtgattta ccatttcctc ttggcgccca ttgcgactaa tttctatacc ctagaaaatt
     7261 tcctttgcca ctatatcgtt cccatctggt ttttagcgga taccctcttt tttgacaaac
     7321 agggtcaata caagatttgg gatccagcag tgtggaccat tttacccttt ctgtatatga
     7381 tgtttgctct ttttaatggc ttggttctaa aactcaatat tccaaatgcc aaggataatc
     7441 ctttccctta cttctttttg aatgtgaaca agggttggaa tgttgtgttt aagtggtgtc
     7501 tgattatctt tgttgcctat atggtagcag gatttatttt ctactttatc aagcaaatca
     7561 agagaaagtc atcctaatac tcttcgaaaa tctcttcaaa ccacgtcagt ttccatctgc
     7621 aacctcaaaa cactgttttg aacaacctgc ggctagcttc ctagtttgct ctttgatttt
     7681 cattaagtat aagatacaag ggattcattt tcgaatttaa gaaggagtct acaaaccaat
     7741 gaggcttctt cttttcttgc ttatttgata actatcaaaa aagtagaaga ttaagagaaa
     7801 tatagaaaga gatttcatga aacaattttt agaacgggcc agcattttgg ctctctccct
     7861 cgttttgatt acctcctttt ccatttcgag tgccctacca gccatgtttg actattatca
     7921 gggttattct aaggaacaaa ttgagctctt ggtgagcttg ccttcctttg gaatcatgat
     7981 gatgttactg ctaaatggtt tcttagaaaa aatatttcct gagcgcttac agattagttt
     8041 gggcttgctg attttatcat tgagcggtac agctcccttc tggtaccaag cctatccctt
     8101 tgtctttgga acacggcttc tctttggttt gggtcttggg atgatcaatg ccaaggccat
     8161 ttctattatc agtgaacgct accaaggaaa aaggcgaatt cagatgttag ggctacgcgc
     8221 ttctgcagag gtcgttggag cttctctcat taccttggcc gtcggtcagt tgttggcctt
     8281 tggttggaca gctatctttc tagcctatag tgctggattt ttggtgctgc ccctttatct
     8341 gctctttgtc ccttatggaa aatcaaagaa agaagtcaag aaaagagcga aggaagcaag
     8401 tcgtttaact cgagaaatga aaggcttgat ttttacctta gctatcgaag cggcagttgt
     8461 agtttgtacc aatacagcta ttaccatccg tattccaagt ttgatggtgg aaagaggatt
     8521 gggggatgcc cagttatcta gttttgttct tagtatcatg cagttgatcg ggattgtggc
     8581 tggggtgagt ttttctttct tgatttctat ctttaaagag aaactgctcc tctggtctgg
     8641 tattaccttt ggcttggggc aaatcgtgat tgccttgtct tcatccttgt gggtggtagt
     8701 agcaggaagt gttctggctg gatttgccta tagtgtagtc ttgacgacgg tctttcaact
     8761 tgtctctgaa cgaattccag ctaaactcct caatcaagca acttcatttg ctgtattagg
     8821 ctgtagtttc ggagccttta cgaccccatt cgttctaggt gcaattggct tactaactca
     8881 caatgggatg ttggtcttta gtatcttagg aggttggttg attgtaatct ctatctttgt
     8941 catgtaccta cttcagaaga gagcttagga ttgattccta agtttttctt ttgatactca
     9001 atgaaaatca aagagcaaac tatagttgat tgagtttgga atagtatgct gtagctgcta
     9061 aaatatttct agaaattaat ttgactttcc taatagagtt gttcatatct tatttcaatc
     9121 tactatagaa agctagccgc aggttgctca aaatagtgtg ttgaggttgc agatggaaac
     9181 tgacgtggtt tgaagagatt ttcgaagagt atgagatttt tatacccata cagtatttgt
     9241 tttaggtcct tgtttacaga ctaatttctt gataaaatag aggctatgac gagatataaa
     9301 gcaactattt cctatgatgg ttatgccttt gctggctttc agcgccagcc tcatgcgcgt
     9361 agcgttcagg aagaaattga aaaaaccttg accagattaa ataaagggca agtcattact
     9421 gttcacggtg ctggtaggac agatagtggg gttcatgccc tgggacaggt cattcatttt
     9481 gacctgcctt atcagatgga tgaggagaaa ctccgttttg ccttggatac ccagtctcct
     9541 gaagatattg atgtgatttc gattgagctt gtggcagatg attttcattg ccgttatgcc
     9601 aagcatagca agacctatga gtttactgtg gatagaggac gtcccaaaaa tccgatgcgc
     9661 cgtcactatg ctacccactt tccctaccca ctcgatgtgg aacgaatgca gattgcaatc
     9721 aaaaagctag agggaaccca tgattttacc ggttttacag cctctgggac tagtgtagag
     9781 gataaggttc gcaccatcac agaagctagt ttaatagtcg atgagacagg acaatttttg
     9841 acctttacct tttcaggaaa tggtttcttg tataaacaga ttcgcaatat ggtggggact
     9901 cttctcaaaa tcggtaacaa ccgcatgcca gtagagcaga ttgatctcat cttggagaag
     9961 aaggacaggc aacttgcagg tcccactgca gcaccaaatg gtttgtattt aaaggagatt
    10021 cgttatgaag aataatcgta ttttagcact ttctggaaat gatattttta gtggtggtgg
    10081 actgtcggct gatttggcta cctatacctt gaacgacttg catgggtttg tagcagtgac
    10141 ttgtttgaca gccttgacag aaaaaggatt tgaagtcttt ccaactgatg ataccatttt
    10201 tcaacatgaa ttagatagct tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct
    10261 ccctactgtc agtgtggctg agaaggcctt ggactttatc aaacaacgcc caggagtatc
    10321 tgtggtgctg gatcctgtct tggtctgcaa ggaaacgcat gatgtagctg tcagtgagct
    10381 ctgccaagag ttgattcgct ttttccctta tgtcagtgtg attacgccta atctcccaga
    10441 agcagaatta ttatccggtc aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca
    10501 gaaattgcat gatttaggag cgccagcagt cattatcaag ggaggcaatc gtcttagtca
    10561 ggacaaggct gtggatgtct tttatgatgg acagaccttt actatcctag aaaatccagt
    10621 tatccaaggc caaaatgctg gtgcaggttg tacctttgcc tctagcattg ccagtcactt
    10681 ggttaaaggt gataaacttt tgccagcagt agaaagctct aaggctttcg tttatcgtgc
    10741 tattgcacaa gcagatcagt atggagtaag acaatatgaa gcaaacaaaa acaactaaaa
    10801 tcgcccttgt atccctatta accgcccttt ctgtggttct aggttatttc ttaaaaatcc
    10861 caacacctac aggaattcta actcttttag atgctggtgt cttctttgcg gccttttact
    10921 ttggtagtcg tgaaggagcg gtagtcggag gactagcaag tttcttgctt gacctcttat
    10981 caggctaccc tcagtggatg ttttttagct tggtcaacca tggcttgcag ggatttttcg
    11041 caggatttaa aggaaaaagt cagtggttag gccttatttt agcaactatt gccatggtag
    11101 ggggctacgc cttgggttct actttgatga atggctgggc agcagccctc ccagaaattc
    11161 taccaaattt tatgcaaaat atgataggga tgattgtagg atttattctt agtcaaagta
    11221 tcaagaagat taagtaatac tcttcgaaaa tctcttcaaa ccacgtcagc ttccatctgc
    11281 aacctcaaaa cactgttttg agcagcctgc ggctagcttt ctagtttgca ctttgatttt
    11341 cattgagtat aaaaagatct tgggaaaaga ctcaatttca gtagaaaagg aagtaaatct
    11401 tcccacatta aaacgcatat taccaaggtt cttatgaact gcaccccaaa agttagacaa
    11461 aaaaaatcta acttttgggt gtttttatta tgaaattga
//
LOCUS       DAVKMO010000056        11115 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVKMO010000056 DAVKMO010000000
VERSION     DAVKMO010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11115
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.056"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            21..401
                     /locus_tag="VW361_001753"
     CDS             21..401
                     /locus_tag="VW361_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744752.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGSFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPYVLMIVSGGVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            607..885
                     /locus_tag="VW361_001754"
     CDS             607..885
                     /locus_tag="VW361_001754"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744753.1"
                     /translation="MRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKLKEST
                     QKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            936..1628
                     /locus_tag="VW361_001755"
     CDS             936..1628
                     /locus_tag="VW361_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU9744754.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1681..4092
                     /locus_tag="VW361_001756"
     CDS             1681..4092
                     /locus_tag="VW361_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU9744755.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GSERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     REAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDENLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKISTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            4342..5043
                     /locus_tag="VW361_001757"
     CDS             4342..5043
                     /locus_tag="VW361_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744756.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPAQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5045..7753
                     /locus_tag="VW361_001758"
     CDS             5045..7753
                     /locus_tag="VW361_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU9744757.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMETTANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEELEQILSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEAKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ANVISSVITKGMVVGETQIQFYWTYSLLALVLSLLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQIGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7849..8340)
                     /gene="tpx"
                     /locus_tag="VW361_001759"
     CDS             complement(7849..8340)
                     /gene="tpx"
                     /locus_tag="VW361_001759"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU9744758.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8463..9392)
                     /gene="psaA"
                     /locus_tag="VW361_001760"
     CDS             complement(8463..9392)
                     /gene="psaA"
                     /locus_tag="VW361_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU9744759.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9424..10272)
                     /locus_tag="VW361_001761"
     CDS             complement(9424..10272)
                     /locus_tag="VW361_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9744760.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10269..10991)
                     /locus_tag="VW361_001762"
     CDS             complement(10269..10991)
                     /locus_tag="VW361_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9744761.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKTKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3258 a         2067 c         2537 g         3253 t
ORIGIN      
        1 ataaaaaagg agattttatt atgaaattaa aaacacttgc tttaattagt ggtatcgtcg
       61 gtcttgtggg aggaatttta cttcttattg gttcttttgt cttgttggga acagcggtaa
      121 atacagctgc tacaactctt aatggaggag ctactgcagg ggctttttca ggtgttgcct
      181 tactcttgaa tgccttgaag attgcaaatc ttgttcttgg tatcattgct attgtttact
      241 ataaaggaga taagcgtgta ggtgcagctc cgtatgtact aatgattgtt tctggtggag
      301 ttagtctcat tccattctta ggatgggttg gggggattct tgctattatc ggaggatctc
      361 tgttccttgc aacattgaag aaattcaaat cagaagaata aaaggtattt tagcatgaaa
      421 agaacaaaaa agtttatcgg tataggagta gctctattat ctctttctct tctagttgca
      481 tgtggaacat aaagttcaaa gaatacttca acaagtaatg atgagaagac agtagcaaca
      541 tccaatagtt caaaagaaac aatcactttc gatacaccgg ttgtaacaga cgatgcgatt
      601 gaatcaatgc gcacttatgc agattatata gatctttata aaaatatttt tgatgattat
      661 tttactaaag ctgaggaagg tttcaaaggc acagctatgg aaaataatga ctcgtttact
      721 aaactaaaag agtcaactca aaaattattc gatgcgcaga aaaaaaggtt aaataatgaa
      781 gatagaatag aaacaaccaa aaacaatgtg attgccaaac attgtcaaac agtcctttcc
      841 tttttggttt tgactagctt ttttgtgaaa aattgtgtaa aatagaatag ataaacgagg
      901 ggaaacctcg gaaaatttaa aggagaatcc atctaatggt aaaattggtt tttgctcgcc
      961 acggtgagtc tgaatggaac aaagctaacc ttttcactgg ttgggctgat gttgatttgt
     1021 ctgaaaaagg tacacaacaa gcgattgacg ctggtaaatt gatcaaagaa gctggtatcg
     1081 aatttgacca agcttacact tcagtattga aacgtgctat caaaacaact aacttggctc
     1141 ttgaagcttc tgaccaattg tgggttccag ttgaaaaatc atggcgcttg aacgaacgtc
     1201 actacggtgg tttgactggt aaaaacaaag ctgaagctgc tgaacaattt ggtgatgagc
     1261 aagttcacat ctggcgtcgt tcatacgatg tattgcctcc aaacatggac cgtgatgatg
     1321 agcactcagc tcacacagac cgtcgttacg cttcacttga cgactcagtt atcccagatg
     1381 ctgaaaactt gaaagtgact ttggaacgtg ctcttccatt ctgggaagat aaaatcgctc
     1441 cagctcttaa agatggtaaa aacgtattcg taggagctca cggtaactca atccgtgccc
     1501 ttgtaaaaca catcaaaggt ttgtcagatg acgagatcat ggacgtggaa atccctaact
     1561 tcccaccatt ggtattcgaa ttcgacgaaa aattgaacgt cgtttctgaa tactaccttg
     1621 gaaaataaaa aattgtaagc ctaggattga tttctaggct ttttatgtta gtatggaagt
     1681 atgataagga ataaaaaaca agattatgta ctggcctaca agcaaccagc ttcaaccact
     1741 tacatgggtt gggaagaaga agctttaccg ataggtaatg gttctttagg agcaaaagta
     1801 tttggcctta tagggtctga acggattcaa tttaatgaaa aaagtctctg gtctggaggt
     1861 ccacttcctg atagttcaga ttatcagggt ggaaatcttc aggatcagta tgttttttta
     1921 gctgagattc ggcaggcttt ggagaagaga gattacaatc tggctaagga actggctgag
     1981 cagcacctaa ttgggccaaa aacgagtcaa tatgggacct atctgtcttt tggggatatt
     2041 cacattgagt tcagccagca aggtacgact ttgtctcagg tgacggacta tcagagacag
     2101 ttgaatatta gtaaggcact tgcgacgact tcttatgtct ataagggaac gcgatttgaa
     2161 cgtgaagctt ttgcgagttt tccagatgat ctcttggttc aatgttttac taaggaaggg
     2221 ttggaaactc tagattttac tatagaacta tccttgacct gtgatttggc ttctgatgga
     2281 aagtatgagc aggaaaaatc tgattacaag gagtgtaagt tggatattac tgattctcat
     2341 atcttgatga agggaagagt taaggataat gatctgcggt ttgctagtta tctagcttgg
     2401 gaaacggatg gagatattag agtttggtca gatagggttc agatatcagg agccagttat
     2461 gccaatctct tcttggccgc taagacggat tttgcccaaa atcctgctag caattatcgc
     2521 aagaaactag atttagagca acaggtgata gacttggtgg acacagctaa agaaaagggc
     2581 tatacccaat tgaaatcaag gcatatcgag gactaccaag ccttattcca gcgtgttcaa
     2641 ttggatttgg aagctgatgt tgacgcatcc actacagatg atttgttaaa aaattataag
     2701 ccacaagaag ggcaggcttt ggaggagctg ttcttccagt atggacggta tttattgatt
     2761 agttcgtcca gagactgccc agatgctcta ccagctaacc tacagggagt ctggaatgcg
     2821 gtcgacaatc ctccttggaa ttcggactat cacttaaatg tcaatctgca gatgaattat
     2881 tggccagcct atgttaccaa tctcctagag acggtctttc cagtcatcaa ctatgtagat
     2941 gatttgcgtg tctatggtcg tctagcggct gtaaagtatg caggaatcgt ctctcagaaa
     3001 ggtgaggaaa atggttggtt ggttcatact caagcgactc cctttggttg gacggcacct
     3061 ggttgggatt actattgggg ttggtcacca gctgccaatg cgtggatgat gcaaaccgtt
     3121 tatgaagcct attcatttta tagggaccaa gactatctta gggagaaaat ttatcccatg
     3181 ttgagggaaa cggttcgttt ttggaatgcc tttttacata aggatcagca ggcgcagcgt
     3241 tgggtgtctt ctccgtctta ttctccagaa catgggccga tttcgattgg caatacctat
     3301 gaccaatctc tgatttggca gttatttcat gattttattc aggctgctca ggaattggga
     3361 ctggatgaga acttgttgac tgaggttaag gagaagtctg atttactaaa tcctttgcaa
     3421 atcactcaat ctggtcgaat cagggagtgg tatgaggagg aagagcagta ttttcaaaat
     3481 gagaaagtgg aggcccagca ccggcacgct tcccatctag tgggactcta tcctggcaat
     3541 ctctttagct acaagggaca agagtatatt gaagcggcgc gtgctagcct caatgatcgt
     3601 ggagatggcg gcacaggctg gtccaaggct aataagatca atctctgggc gcgtttggga
     3661 gatggcaatc gagcccataa attattggca gagcagttaa agatatccac cttgccaaat
     3721 ctttggtgta gccatcctcc ttttcagata gatggtaatt ttggtgctac tagtggcatg
     3781 gcagaaatgt tactccagtc tcatgcagct tatctggtac ctctagctgc cctacctgat
     3841 gcttggtcaa caggttctgt ttcaggctta atggcacgtg gacattttga agtgagcatg
     3901 agctgggaag ataaaaaact cttacagttg accattttat caaggagtgg aggagatttg
     3961 cgagtttctt atccagatat tgagaagagt gtgattaaaa tgaatcaaga aaaaataaaa
     4021 gcgaaatgca tggggaaaga ttgtatttcg gtggcaacag cagaaggtga tcttgttcaa
     4081 ttttattttt aagaagatgt tataaggcag taatttgaaa ctgcctttta ataaggattt
     4141 aagaatatag gcagtttcca actagttgaa aaagcgttat aatgataata ggaagtaata
     4201 ctcaatgaaa atcaaagagc acaaactagg aagctagccg caggttgctc aaaacagtgt
     4261 tttgaggttg tagatggaag ctgacgtggt ttgaagagag attttcgagg agtataattt
     4321 gtttgataga gggtgggtct gatggcttat attgagatga aacactgtta caagcgttat
     4381 caggttgggg acacggagat tgtggccaat cgtgatgtga attttgagat tgaaaagggg
     4441 gagctggtta ttatccttgg tgcttcaggt gcaggcaagt caacagttct taaccttctt
     4501 gggggaatgg ataccaatga tgaaggggaa atctggattg atggtgttaa tattgcggat
     4561 tatagttccc accagcgcac caattaccgt agaaatgatg tggggtttgt ttttcagttt
     4621 tataatctag tttctaatct gacagctaag gaaaatgtgg aactggcttc tgaaattgtg
     4681 acagatgcct tgaatcctgc tcaggttttg acagatgtag gtctggctca tcgtctcaat
     4741 aactttccag cccagctttc tggaggggag caacagcgag tctccattgc acgcgcggta
     4801 gccaaaaatc ctaaaattct tctttgtgat gaaccgactg gagccttgga ttatcagacg
     4861 ggcaagcagg ttttgaaaat tctccaagat atgtctcgtc aaaagggagc gacggtgatc
     4921 atcgtgactc ataatggagc tttggcgccc attgctgatc gcgtgattca tatgcacgat
     4981 gccagtgtca aggatgtggt gctcaaccag catcctcagg atattgacag tttggagtac
     5041 tagcatgatc aagcgaaaaa cttattggaa ggacttaatt cagtccttca caggctccaa
     5101 ggggcgtttt ttatccatct tgatcctgat gatgttggga tctctagcct tagtaggcct
     5161 caaagtaacc agtcccaaca tggagacgac agctaatgct tatttaacaa ctgctcaaac
     5221 cttggatttg gcagtcatgt ctaactatgg cttggatcaa gcagaccaag aagaactaaa
     5281 acagacggag ggcgcagagg tcgagtttgg ctatttgaca gatgtgacta tggataatgg
     5341 gcaggatgcc attcggctgt actccaaacc agagcgaatt tcaacctttc agctaagaaa
     5401 gggacgactt cctcagtcag acaaggaaat cgctttggcc actcatttgc aaggccaata
     5461 cagcgtggga caggagatta gttttaaaga aaaagaagag ggtcattcct ctttaaaaga
     5521 ccatacttat accattactg gttttgtgga ttcggctgaa atcctctccc agcgagatat
     5581 gggctacgca ggaagtggaa gtgggactct gacagcctat ggggtgattt tacctagtca
     5641 atttgatcag aaagtctaca atatagctcg tttgaaatat caagatttag caggtttaaa
     5701 tgccttttca tcagcttatg aagaaaaatc caagcaacat caggaagagc ttgaacaaat
     5761 tttatcagat aatggcaagg tacgtctgca acttttgaaa aaagaaggac aagagtctct
     5821 agacaagggg caagagaccc ttgacaaggc tcagactaat ttgcaggaag gcaagcgtcg
     5881 tttagcagct gctcaagctc gtatacaggc tcaagaaagt caactagcct tgtttcctca
     5941 agttcagaga gagcaggcta gtgctcaact tacccaagcc aagcaggaat tgggcaagga
     6001 agaggccaaa ctaaagcaag ctgaacaaaa tctagcccaa gaaaaggaaa aattagaaaa
     6061 acatcagcaa gtcttggacg atttggcgga gccaaggtat caggtctata atcgtcagac
     6121 catgccaggt ggtcagggct atcttatgta tagcaatgct tcatccagta ttcgagcagt
     6181 gggcaatatc tttcctgtgg tactttatgc cgtagcagcc atggtgacct ttacgaccat
     6241 gactcgcttt gtagacgaag agcgaactca tgcagggatt tttaaggcct tgggttatcg
     6301 tagtaaggat attatcgcca agtttctcct ttatggacta gtagctggga ctgtcggaac
     6361 ggctctaggt agtatacttg gtcattattt gctagccaat gtaatttcaa gtgtcattac
     6421 aaaaggcatg gtggtgggag aaactcagat tcagttctat tggacctata gcttactagc
     6481 tcttgtcttg agcttgttgg cgagtgtgtt accagcctat ctggtggctt ggagggaact
     6541 tcatgacgaa gcagcccagc ttctacttcc taaacctcct gtcaaaggag ctaaaatatt
     6601 attggagcgt atcggtttta tctggcgtcg tctcagtttt actcataagg taacagcccg
     6661 caacatcttt cgttataagc agagaatgtt gatgacaatc tttggtgtgg caggttctgt
     6721 agctctgctc tttgcaggtt tgggaatcca atcttctgta gcaggagttc cgtctaaaca
     6781 gtttcaacaa atccaacagt atcagatgct tgtctctgaa aatcctagtg cgaccaatca
     6841 ggacaaggta gagctagcag aagtgttgaa agggcaggag atactagcct accagaaaat
     6901 ctattctaaa acgctagaca aggatttcaa aggcaaggct ggtcttcaaa acattactct
     6961 tatgatgata gagaaggaag atttgactcc ctttatccat cttcaacatc atcagcagga
     7021 gctgacatta aaagatggca tcgttattac agctaaactc gcccagctgg caggtgtcaa
     7081 ggttgggcag actttagaaa ttgaaggtaa ggaactaaag gtcgctgcta ttactgagaa
     7141 ctacgttggt cactttattt atatgagtca ggctagctat gagcaacttt acggacagct
     7201 accccaagcc aacacttatc tggtctcatt aagggatacc agtgcaacta gtatcgaaag
     7261 tcaggcgggc ttgcttatga atcaatctgc ggtgtccagc gttgtccaaa atgcttcagc
     7321 cattcgactc ttcgactcta tcgctagctc actcaatcag accatgacca tcttggtcat
     7381 cgtatcggtt ctattagcta ttgtcatcct ttacaatctg accaatatca acgtagctga
     7441 gagaatccgt gaactctcca ctatcaaggt tctcggtttt cataataatg aagtcaccct
     7501 ctacatttat cgtgagacga ttgtgctgtc ccttgtggga atcgtacttg gtctggtagc
     7561 tggtttctat ttacaccaat ttttgattca aatgatttcg cctgcgacta ttctctttta
     7621 tccgcagata ggctgggaag tctatgtaat cccagtggca gcagtaagca tcattttgac
     7681 cttgcttggt ttcttcgtca attattatct gagaaaggtt gatatgttag aagccctgaa
     7741 atctgtagag taaggtagtt atttttagct gattgaactt ctatttacta atattcaaaa
     7801 atcctccgtt tcaaagagca gggaactctt tgtgacagag gattttttct atagggcttt
     7861 agcagctgca attgcggctt cgaagtttgg ctcagaattg atattatcca cgtattcaac
     7921 gtagcgaatc gtattgtcag tatcgaggac aaagactgcg cgtgctaata ggtgccattc
     7981 gttgatcaag agggcataat cgcgcccgaa agaatggtca aagtagtctg aaagcataat
     8041 ggcattgtca aggccttcag caccgcacca acgtttttga gcaaaaggta ggtccattga
     8101 aacagtcaat acgaccgtgt tgtccagtcc agccaattct tcattaaaac gacgtgtttg
     8161 agttgagcag atgcctgtat cgatagaagg aacgacactc aagacttttt tcttgccatc
     8221 aaaatcagcc agagattttt tagaaagatc tgttgtagta agagaaaaat caagcgcctt
     8281 gtcgccgact tgtagttgtt tacctgtaaa gctcacagga tttccgagaa aagttaccat
     8341 aggatactcc aatctttttt cttccattgt atctgaaaca gtcagaattt tccaatgatt
     8401 tgaccggaaa tgtgggcata gaaaaaacgc cagctcacat gagaatgacg tttttcagag
     8461 gcttattttg ccaatccttc agcaatcttg tcaaggttgt atttcatcat gctgtagtag
     8521 ctgtcgcctt ctttaccttg ttctgcgata gagtcagtaa agatttgtgc gtagattggg
     8581 atgtttgtgt cttgagaaac agttttcatt ggacggtcat ccacacttga ttctacaaag
     8641 agtgatggaa cttttgtttg gcgaagtttt tcaaccaagg tcttgatttg ttcaggagtt
     8701 ccttcttctt cagtattgat ttcccagatg taggcacttg ggacaccata ggctttagag
     8761 aagtatttga atgctccttc gctggttaca atgagtttct tttcagcagg gatcttatta
     8821 aatttatcct tactttcttt atcaagtttg tctaacttat cagtatattc tttgagattt
     8881 ttttcataga attctttatt gttagggtct ttggcgctca attgtttggc gatattttta
     8941 gcaaaaataa taccgttttc aaggttaagc caagcgtgtg ggtcttcttt tcctttttca
     9001 ttttgacctt caaggtagat aacatcaacg ccgtcgctga ctgcgaagta gtctttgttt
     9061 tcagttttct tggcattttc taccaatttt gtaaaccaag cattgccacc tgtttcaagg
     9121 ttgataccgt tatagaaaat caaatcagcc tcagaagttt tcttaacgtc ttcaggaagt
     9181 ggttcgtatt cgtgtgggtc ttgcccaatc ggaacgatac tatgaaggtc aattttgtca
     9241 ccagcaatat ttttagtaat atcagcgatg attgagtttg tagcaacaac ttttagtttt
     9301 tgaccagaag ttgtatcttt ttttccgcta gcacatgcta caagaatgat tgcagaaaga
     9361 aagagaacga gcaatgtacc taattttttc attagatcct ccaatttatt agggctttgc
     9421 cccttatttt aacaaatgtt tatttttcag tttcaaatat cgttgtttgg gagcgataaa
     9481 gaagctaatg agaaagaaac tagcagctgt aagcacgata ctagaacctg ccgcaacatt
     9541 aaaactatag ccaataaaga gtcccaaaac tgaagcagta gctccgaagg ttgaggaaag
     9601 gaaaatcatg cttttcagac tattagcata cagataagca gttgcagctg gggtaatcag
     9661 catggctaca atcaggatag ttccgacact ttgcatggct gtcacagaca cgagagtcag
     9721 gagtaccatg agaaggtagt gatagaaatt gacaggcatt cccatggctt tagccaagag
     9781 ttcatcaaag gaagttatca agagttgctt gaagaaaatc cagattaaca agaggatggc
     9841 tgcccccaca cccatagtaa taaacatatc cgtatcttgg acggccagga tattaccaaa
     9901 aaggatatgg aaaaggtcag ttgaactttt agcgacacca atcaagatga taccgagggc
     9961 taagaaagaa gaaaaggtaa tgccgatggc ggtatcgctt ttgataatcg agtttccttt
    10021 gatgtaggta atgatgatgg cagctagcaa tccaaagaca atggctccga taaagaagtc
    10081 aaggcccaag atgaaggaga gggctacacc tggtaagaca gcatgtgaaa tggcatctcc
    10141 catgagtgac atcccgcgta gaataatgaa acatcccaca gctccagcta caatcccgac
    10201 gacaatagct gttatcaagg cattttgtag gaaatggaat ttttgcaatc catcgataaa
    10261 ttctgcaatc ataggtcacc tccattgaaa aagagttgat taccgtaagc ttcttttaga
    10321 ttggtttcgg taaaagtttc ttttgttgga ccaaaggcaa tcacttctcg attgacaagt
    10381 aagacttgat cgaagtagtg gggaatcttg ctgaggtcgt ggtgaacgat gagaaccgtc
    10441 ttcccagctt ttttcaaatc tctcagcgta ttcatgatga tttcctcact gacagagtca
    10501 atcccagcaa agggttcatc caagaggata tagtcggctt cctgcaccaa acatctggca
    10561 atcaaaaccc gctggaattg acctccagac agttgactaa tttgacgttc agcgtagtca
    10621 gctaggccga cgatttcaag ggcctcttgc actttcttcc aatgtttagt ctttaaactt
    10681 cgaaagagag gaatagaggg aaatagtcct aacgagacgc attccttgac cttgatggga
    10741 aagttgtagt cgatattgat tttttgttcg acataggcaa ttcggtgtaa ggatttttta
    10801 acttccttgt catcgagaaa tgcctgacct tgatgtggga taattcccag catacctttt
    10861 aatagtgttg atttcccagc gccgtttgga ccaatgatgc cggtaattgt tggtccatgg
    10921 agcactagtg aaatatcctt aagtgccaac gtttctttgt aggagacact gaggttttcg
    10981 atacgtatca taaacttgta ttcctcctgt ctcttaatat acattaaaaa aaaaattaag
    11041 tcaagttaat ttttgaaaaa attaaaataa taactgaaaa atagattcta aagataactt
    11101 tcaggataaa tttct
//
LOCUS       DAVKMO010000057        10741 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVKMO010000057 DAVKMO010000000
VERSION     DAVKMO010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.057"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(102..1526)
                     /locus_tag="VW361_001763"
     CDS             complement(102..1526)
                     /locus_tag="VW361_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9744762.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTATILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2071..4350)
                     /gene="pulA"
                     /locus_tag="VW361_001764"
     CDS             complement(2071..4350)
                     /gene="pulA"
                     /locus_tag="VW361_001764"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU9744763.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLTPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGTYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTVAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4462..6420)
                     /gene="ligA"
                     /locus_tag="VW361_001765"
     CDS             complement(4462..6420)
                     /gene="ligA"
                     /locus_tag="VW361_001765"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU9744764.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDHLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDKIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6513..7691)
                     /locus_tag="VW361_001766"
     CDS             complement(6513..7691)
                     /locus_tag="VW361_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9744765.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSIIVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FFLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7771..8634)
                     /locus_tag="VW361_001767"
     CDS             complement(7771..8634)
                     /locus_tag="VW361_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU9744766.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQETMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8637..10538)
                     /locus_tag="VW361_001768"
     CDS             complement(8637..10538)
                     /locus_tag="VW361_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9744767.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAKIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3228 a         2357 c         1910 g         3246 t
ORIGIN      
        1 atttcaatct attataatac caaaaagttc gtattttttc tataattatt attttatagc
       61 aaaaaaataa aaccaggaaa acaatttcct ggttttacac gttatttcac atcaaaaaca
      121 atggatttga catttgtcat cgcttcaatg ctatatttaa ttccttgcac tccagctcca
      181 gaacctttga caccaaggaa tgggaaatta tctggaccac gctgggtttt attattaatg
      241 tggactgtac ctacttcaag cttttcagca atttcaaagg cttttttgaa atcatttgta
      301 aagactgatg attgaaggcc gaattcagat tcgttggcaa aggcaatagc ttcctctaca
      361 ctagccacac gaatgattgg taaaacagga ccaaatggct cttcccatgc cactttcata
      421 tcttttgtaa cttggtcaaa aagcactggc cagaggagat tgccctcacg tttgattggt
      481 gtaagagcct gagcctcttt ttcttgtgca tcctcaatca agccccaaat gaagtcggct
      541 gaagcattgt caataacagg tgtaatatca gcattgtcaa atggatcacc aactgttaat
      601 ttagaaactt cttcctgaag caaagtagct aatttatctg ctacactttc gagaacaatg
      661 acacgtttaa tggccgtgca acgttgtcct gagtagctaa aggctcccgc aacaatttgc
      721 ttggcagcat gttccaaatc tgcatcttct agtacaagag ctgcatcttt cccaccaagt
      781 tccaacatga taggacgcat accagctaaa cgaccaatac gttctccaat aggagttgaa
      841 cctgtaaagt tgatgaagtt gacttctttg tgctcaatga tataatcccc aatttctgaa
      901 ccacgacctg taatggtgtt gaaaacacct gccggaatcc ctgcttcttc aaatgcttta
      961 gccaacaaga gtccagaaat ggaaccttgt gttggtggct tcaacatgac cacattccct
     1021 gcaatcaagg caggtgcaat tttagaagca gataaattaa ctggataatt aaagggagca
     1081 atcgctagca cgataccaac tggttcacga cggacaacag ccagtttgtt tttacttgct
     1141 gcctcaaaac caccaccttc cattgcttgt ccagtgatac ggagaccttc ctcagcagca
     1201 taacgaatca agtctgctgt acgcactact tctccaattg ctgctttaat cccttttgct
     1261 acttctttgg caaggatagt accaattttt tccttatcgc gttctaaaat agttgctgtt
     1321 ttatgcaaat aagccgcacg ttcaattgct gataaagctc gccatgctgg tagggctgca
     1381 cgcgcagctt gcatagcctc atcagcttca gtctgagtca tggctggaac tgtacccaat
     1441 tcttcttgat tgattggtga ataaatcgta atttcttgtt cagatgattt ccattttcca
     1501 tttactaaat tctgatatct tgtcaaattc ttgtcctcct gaaaatgatt aagatatatt
     1561 ttaccaaatt ttcagaaaat cacaaccctt tttgcaaaat ttttgagatt attttcacaa
     1621 gcttgatttt tcaaagtata ctcaataaaa ataaaaaaaa tccactacat caaggcgaga
     1681 ctaatgtggt ttgaagaaat tttcgaagag cgtgaatgag tatcatctat agtaaaataa
     1741 aaaaactgaa caatttggtt ggggacagtc aaaccaattt ctcacaatgt tttagaaaca
     1801 agggtgtgct attccaattt caggctacta taactgtcat agattgctga aacaaagtct
     1861 aggtaaaagt cttcataata aaaagacccc ctatcaagtg ttcaaaaact ttgataggag
     1921 gtcttgtttt gtgaaaatat ttatcaaatt ttctatacaa gtgagctgtt agccaggttc
     1981 tttctattct ttcaatttca atgaatggat tttttaccaa tactcataac tgggaatttg
     2041 tctgtctaaa aatagcgaga tagatggtat ttataaaaca ctcaagacag ctagactaat
     2101 atcatttaaa acattatctt cttttgagcg actgttggtt accaacatag ctaaatttcc
     2161 tgcattttca aattgatagg gttctgattt agcattcaca actaccaaga ggtgttcttt
     2221 gccgtgaact tcatagataa ggcagccgct atgttcaatc gcagaatgca caaagacatg
     2281 atggtaaatt tcatcatagc tagagtaaga aaaagcaaca gtttttgtct tcaatcggat
     2341 gacttgacgg ataaactcaa tactgtcttg acgctcatta atcaagttcc agttcacttg
     2401 gttcacactg tcaggagcat tatagctatt catcgcacgc tctctatcat catgggtcaa
     2461 ctcaccattt tcaccagtcg caaccagttt ggtacgacca aattcttgac cgatttccat
     2521 aaaggccatc ccctgcatga gcagattcat ggctgtggca gtttcgacct tgcgcatgat
     2581 ttgctctgaa ctttggtctg gatgaagggt tgccaataaa tcgtgaagat tgtaattgtc
     2641 atgggcttct acatagttaa gcacctgatt tggatgtgta taggttccta attcacgact
     2701 tcctaggatt gctttagcta gaattggctc tgtcgcagca ccactgacaa aacctgactt
     2761 gatagcacca taaacttctc cccctttgac agcatcgcgc tgattgtcat taaagaaacc
     2821 aatatttggc atctggtagg cattgtcctt cttggcctta tcataagggg taagacctgt
     2881 tcccatatcc catccttctc catagaggat aatgttggag tcgatttcat ccaagctttg
     2941 acgaatcatc tgcatggtct tgacatcatg aatccccatc aagtcaaaac ggaagccgtc
     3001 aatattatat tcctgcaccc agtatagaag agaatcaatc atatacttgc gaaacatttc
     3061 gtgttcactg gctgtttcat ttccaacacc cgttccattc tggaaggtac catctggatt
     3121 catacgataa tagtaatcag ggactgttgt ttggaatggt gcatcaacaa ctgagaaggt
     3181 atggttatag actacatcca taatgactcc aatacccgca tcgtgataag cttgaaccat
     3241 caccttcaaa tcacgaatga cctgagctgg atcatctgga ttagttgaaa aactagtttc
     3301 tggcgcgtta tagttttgtg gatcataacc ccagttgtag gttacatttc catcctcatc
     3361 gtattcttta tgacggtctg caattggttg caattgaaca taattgtagc ccagcttctt
     3421 gatgtaatca aaagcagttg actggccgta ttggttaact gttccagcct gagcagcacc
     3481 caagaaagtt cctcgaagat gttcatctac acccgatgta ggtgatttag tcaaatcacg
     3541 aatgtgcatt tcacagataa ctgccttaca tggattttcc aagcgccaag tagcctccga
     3601 accgtgctta acctcgaagt tttcaacttg cttttctaca tggctcagaa tagctgaacg
     3661 tttgccatca gggctggtcg cgattgtata aggatcacgt gtcagtgttt ggtgatgagg
     3721 gaattggact tgatactgat aagtcttacc taccaaatct tcttcaacat ccaaactcca
     3781 gacaccgatt gtattgtcct tatgattata agagtagcta ttgcctcttt tcatctcaaa
     3841 agtcttccaa acgggtgcat cattagcagc tgattcataa acgacaactt gcacttctgt
     3901 cgctgtaggt gaccagaggg aaaaatgagc ctgattgtcc tctacacggc aacccaattc
     3961 tccttggtaa ccccaatgat gatcaaaact agcactgtta atggccttat caaaggcaaa
     4021 aggattttga tttttataga aaggactggc aatagcagga ttttcagagt aataaatcct
     4081 atcatcgcct tccaaaatcc agacctctgt taatagggga tagtgattaa aacggataga
     4141 atattcttta ctagtttgac ctgtatgaac cacaaaattc aagctttcta taacatgtga
     4201 acttgggtgt tcaaagctaa ataaagctcc aaaataatct tctttgtagg ttagcaaatc
     4261 aattcgttga tcctgacttt ttacaaagga gcaagtgtca tattctccat tcttacgatg
     4321 gtaatgaatg cgcatagggt agttatacat tttttatttt tcctttttac tttgtttcta
     4381 tttcactaat aaatttttgt caatctcgtc tcaattaaca gacatagtca tattctctaa
     4441 actctgtttt taaacgatcc attacaaact ttctagccat gcctcatctc tgacctggat
     4501 accaagttct tgtgcttttt gcagtttact tccagcgtct gcacctacca cgacgaggtc
     4561 ggtcttttta gaaacactac ctgtcacttt ggcacccaga ctttcgagtt tacttttagc
     4621 ttctgagcgc ttgagtcgtt ccaattttcc tgtcaatacc acggtcaaac ctgacaaggc
     4681 cgcatccgct actaccgtct gtcctttata gtccagattg accccagttt ctttcaattc
     4741 tctgagcaga atttcagagc cttctgtcgc aaaataagtc tgaagacttt tggcaatcac
     4801 gccacctaga ctttcaatac tagccacttc ctctgaatct gcctgataca gattttcaat
     4861 tgaatggaaa tattgaagta aaagctgact agccttgctt ccgacatgac gaattcccaa
     4921 accaaataag agcttctcgg cagaattttc ctttgatgct tggatagcct gatacagttt
     4981 agcagcggac ttttccttaa ccccctctaa aaggaggaaa tcctcttctt gcaaacgata
     5041 aatatccgcc acatccttga ctaaattagc agcaaaaagc ttctcaacaa tagatggacc
     5101 aaggcctgta atattcatag catcacgaga agcaaagtga atcaagcctt ccatgatttg
     5161 agcagggcaa cgcggattga tacaacgtag ggccacttca tcttcaaagt gcaacaagtc
     5221 agagttacaa cttggacagt ttgtagggat atctagtttt tcttcagaaa cccgtttgga
     5281 ctctaccaca cgtaaaacgg cagggatgat gtcaccagcc ttatatacaa tgaccgtatc
     5341 gtcttttcgg atatcttttt cagcaatata atctacattg tgcagggtcg cacggctaac
     5401 agtcgtaccg gcaagttgta ctggtgttag attagcagtt ggagttacaa caccggtacg
     5461 gccaactgtc cagtcaactg ataagagttg agcttctttt tcttcagcag ggaacttgta
     5521 ggctactgcc cactttggag ccttaacggt aaaaccaagt tcttcttgac ttgctaggtc
     5581 gttgaccttg attaccactc catcaatatc gtaaggcaga ttttcccgtt cctgtcctac
     5641 ttcttggata aaattccaga ttttatctat gttttcagcc aagattcgct taggattgac
     5701 cacaaaacct agttgttcta ggtacttcaa acccttttct tggctatcac gagttgaagg
     5761 gctggcttct tgatagagaa acgttgcaag attacgcttg gcaactactg ctgtatccaa
     5821 ctgacgcaga gttcctgctg ccgcattacg aggattagca aattcaggct ctccattttc
     5881 ttggcgcact tggttaactt ggtcaaagga agcgcgtggc atgtaacatt ccccacgaac
     5941 tgtgatatct agttcttctg gcaaagtcaa agggatgtcc ttaacacgct tgaggttttc
     6001 tgtgatattt tcaccaattg aaccatctcc acgtgttacc ccagcaacca aaatcccctt
     6061 ttcataagtc agcgagatag ataagccatc gattttcagc tcacaaatat aggtcggatg
     6121 agcaacttcc ttacgaacac gcgcatcaaa agcatctagc tcctcacgtg aaaaagcatc
     6181 ctgcaaacta taaagaggat actgatgact gtatttttca aaaccatcta aaaccttgcc
     6241 accaacacga tgagtcggac tatctgctag cacttgctct ggataagcag tttctaactc
     6301 gaccaactca cggtaaaggt ggtcatactc actgtctgaa accgagggat tatcgctggt
     6361 atagtactca gtcgcatagc gattgagcaa agcgactaac tcattcattc ttttattcat
     6421 aagaccattt taccataaaa caaaccctcc tcacaaacga gaagggcgga aaaaacactt
     6481 agtttgaaat tatttttgaa actcaagcaa ccttatatca atttttcaaa atgagttcga
     6541 acataaataa acgatataca agacaagatg ataacaccac ttccaattat caggaaagaa
     6601 gagagatgta cacttggcaa gactgtcata aatccttttg caataggcat aaatagaata
     6661 gctaaggtaa aaattgtact cagtactctt ccaagaaatt cgctctcaac cttggtttgt
     6721 acttgagtaa aaaagtgaat attaaaaatc gtcataaaca attcacaaac taaatttcca
     6781 gaaaaggaaa gaaaagttgg aagtggtaat cccatcataa aaactccgac acctgtcaaa
     6841 gccagtaaaa tcaaaagatt ataaatatta gctttaattt tactagctag aagagcccca
     6901 atgatggaac caatagcccc catagttaaa atacttgcat aggctccttc tgacccgtaa
     6961 agctgatttg aaaagggaag tagaaattca aaagctgcaa aaaagaaatt aacgctggaa
     7021 gctaccagca aaaagaagaa aatttcttgc tgatgccaga tatagtgtaa cccatccttg
     7081 atatctacaa aaatatctct cccagtaaaa gcctttttct cttgaacttt tgcttcctct
     7141 tttggaagga aagccactag aacaaaagca atgaaaaaag tcagcgagtc tagcagtagc
     7201 gtcatatgga gacttgcaaa ctgtaaaaca aggaaggaaa gaacaggaga gctaacacct
     7261 acaacctgca aaaccagctc taagcgagaa ttatagatca caatctcatc tttctccacc
     7321 acttcagtta tgatagcttt attggctgtg cgagaaaagg caaaagcaat agcctgcaca
     7381 atgttagcaa caatcaaagc gccaatcatc cagctatcat tccttatgaa agaaatagcc
     7441 agacaaagaa tcccacaaac aagatctgcc gtcattaaaa tcttacgacg agaaaaacgg
     7501 tctgaaataa ctccgccaaa gggattgacg ataatagatg tgacgagctc agaaatctga
     7561 tacattccta aaactgtctg tcctatagtc cccatagaag ccaaccagac actatttcca
     7621 taatcataga gcatatttcc cattttattg atagccccac ggctaatcaa ctgcactgca
     7681 tagcgattca tattaaagct cctctcaaat tttgaaacta ttgtatcaaa accgaaagga
     7741 gctttttatt ttttccctta tttgggaaaa ttaacttttg acaaattttt cgtagtgttc
     7801 ctgataatag gctacttgct ctggaagacc taacacatca aaaatatgca tggtctcttg
     7861 catctgctta cagccttctt tacactgtcc tttttgatat aaggcaaaac cttttaaata
     7921 atggaaaaca ttacgctcat aaagcttaat acctttgtca ataatcttct ctgtataagc
     7981 ctcaaaatag ttggcattat aaaaagaaga atgctctaaa caatgctggt aacaattgag
     8041 ggccaaaatc aacactaatc tcttatggcg actaatctct tggtaaaatt cctccctctc
     8101 cataacttct ctaccaatcc gagtgacata gtctacatcg tagaaactat agaggttacc
     8161 gaaaagaatc aactcataca tggtccattc ttctgttttg aagagataat ctgctacctt
     8221 atccaaatca tcctgcttca tatcataact cgcatctctt tgacaaatca gaccttgtag
     8281 caaaatccag ttcagctcaa aataaagggg agtcgtcgaa ctcttagact tttcaagttg
     8341 ttctctttga agcttttgaa aacctgcaat atcgtttgaa tagtaaagtg ggataatctg
     8401 tgccatcata gacacatgtt catgattatg aaaattcctt gccttatcca tgaaattttc
     8461 gattgttaca tgaatgttat ccaaaatctc aaagaaacgg gagactgcca ggtcagactc
     8521 cccaagctca aagcgagata actgagaggt agagcaggat tcgcctgctg cttcctttaa
     8581 agaataattt ccacttgttc gaaattcacg aaatactttt ccaagatgtt ccatctttac
     8641 acctgatctg ataattcttc ccactcaagc atagcttctt cctgacgatg gctgattttg
     8701 tccagctcag cctgtaattc catgagtttg tcggcatcgt ttgtttccaa catttgttca
     8761 gaaatggctt ggctttgact ttctagctct tcaattttag cttctagact ttcgatttgt
     8821 cgcatgagtt tgcgaacttc tttttgactt tctttctggg cctgatagtc attgactgga
     8881 cttgcttcct ttgcttgatt gctagttgaa gcttcctcag tctgactcat ttctgctgtt
     8941 gctttcttct caacatagta gtcgtaatct ccaaggtaga gagttgaacc attctcagac
     9001 aattccaaaa catgagttgc cacacgattg ataaagtaac gatcatgact gacaaaaagc
     9061 aaggtaccat caaagtcaat caaagcattt tccaacactt ccttgctatc aatatccaag
     9121 tggttggtcg gctcgtcaag gatcaggaag ttgttgtttt ccatagacaa tttagctaaa
     9181 agcaaacgag ctttttcgcc accagatagc atgccgactg attttttaac atcatctcct
     9241 gagaaaagga aggctccaag acggttgcgg atttcaactt ctggtgtcag tttgaaatca
     9301 ttccagagtt catccagcac cgtattactt ggtgtcagct tgctttgggt ttggtcatag
     9361 taaccaacct caacattagc gccaaagcgc ttttcacctt tgataaaagg aatctggtcc
     9421 acaatagact tgataaaggt tgacttgccg ataccatttg gaccaacgat agcgacagca
     9481 ttcatcttac gaagatctag gttgataggt tgtgacaaga cttccccgtc ataaccaata
     9541 gcagtatttt caacagtcaa aacaacattg cccgacgttt tttcagactg gaaggtcatg
     9601 ttggctgctt tcttgccagc ttcaggcttg tccaaacgct ccattttttc tagttgttta
     9661 cggcgagatt gagcacgttt agtcgttgaa gcacgaacta gattgcgatt gacaaagtct
     9721 tccagagcag cgatttcctt ctgttgcttt tcatagtttt ttgcctcagt agctagcttt
     9781 tgctccttca attcgacaaa acgagagtaa ttccccacat agcgatccaa ggaatgcttg
     9841 gtcaaatcta gcgtaattgt cgcaaccttg tccaagaaat aacggtcgtg gctgacgata
     9901 atgagggcac cgctatagtt taccaagtaa ttctctagcc aggcgatggt ttcaatatcc
     9961 aagtggttag ttggctcgtc caagaccaag agattgggct tttcaaggag cattttggca
    10021 agtgccaaac gagtattttg accaccagaa agctcagcaa ttttcatctg ccacatagac
    10081 tcgtcaaact tgaatccatt caaaatcgct cgaatatcag cttcataggt aaagccacct
    10141 gcttggcgaa aattctcaga taagcggtca taatctgaca tcagtttatc caaatcctca
    10201 ccagactttt cacccatctc cagctccatc tgacgcagtt gtctctccgt ccgacgcaaa
    10261 tcattaaaga catgaagcat ttcatcgtag atggtatttt cagactcaaa acggctatct
    10321 tgggctaggt aagacagaga aatatctttt ttcttattga tttctccgct agttggctcc
    10381 tcttctccaa ctaaaatctt caaaagagta gacttacctg caccattttt cccaacaaga
    10441 gcaatccgat ctcgttcatc aacctgcagg ttgatattat cgaaaagaac ctctcctgca
    10501 aaagaacgtt caattttatt agcttgtaaa ataatcatac aagtagtata gcatgtttcc
    10561 ctaagtcatt caagataatc gtaagtcttt tagtacaact tttataacat aaaataaact
    10621 aaattatgta tattttatat tagattcctt cactatcttg ttggattttc taaccagcta
    10681 atcttgtttc aaatagttat cgcacaagtc tattatttaa ttcttttcat tatttacgta
    10741 c
//
LOCUS       DAVKMO010000058        10663 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVKMO010000058 DAVKMO010000000
VERSION     DAVKMO010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10663
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.058"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(6..1220)
                     /locus_tag="VW361_001769"
     CDS             complement(6..1220)
                     /locus_tag="VW361_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9744768.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1376..1669)
                     /locus_tag="VW361_001770"
     CDS             complement(1376..1669)
                     /locus_tag="VW361_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744769.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1831..2283
                     /locus_tag="VW361_001771"
     CDS             1831..2283
                     /locus_tag="VW361_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU9744770.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2318..3706)
                     /locus_tag="VW361_001772"
     CDS             complement(2318..3706)
                     /locus_tag="VW361_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9744771.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3772..4734
                     /locus_tag="VW361_001773"
     CDS             3772..4734
                     /locus_tag="VW361_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU9744772.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4731..4877)
                     /locus_tag="VW361_001774"
     CDS             complement(4731..4877)
                     /locus_tag="VW361_001774"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744773.1"
                     /translation="MNTIERTRRLVKGCATHCFEVADETDEVSNHTYGKATLTWFAEI
                     FEEY"
     gene            complement(4941..5951)
                     /gene="ccpA"
                     /locus_tag="VW361_001775"
     CDS             complement(4941..5951)
                     /gene="ccpA"
                     /locus_tag="VW361_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU9744774.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6376..6975)
                     /locus_tag="VW361_001776"
     CDS             complement(6376..6975)
                     /locus_tag="VW361_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9744775.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQTKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSEKLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(6977..8074)
                     /locus_tag="VW361_001777"
     CDS             complement(6977..8074)
                     /locus_tag="VW361_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9744776.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVIGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLFYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     AKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESTAAMILLELVTNIIKHAKAFKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(8074..8811)
                     /locus_tag="VW361_001778"
     CDS             complement(8074..8811)
                     /locus_tag="VW361_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9744777.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSSMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPVVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFSVGHFVRGVDMSLASWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELIKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(8813..9697)
                     /locus_tag="VW361_001779"
     CDS             complement(8813..9697)
                     /locus_tag="VW361_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744778.1"
                     /translation="MNMIKVQGLHKNIKGKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLSQENVIVQKLKVKELIAFFQSIY
                     PNPLSEQEIDQLLQFDQQQKEQFAEKLSGGQKRLFSFVLTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTREADSFWQLLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(9684..9878)
                     /locus_tag="VW361_001780"
     CDS             complement(9684..9878)
                     /locus_tag="VW361_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744779.1"
                     /translation="MKKATIYFFIGLSLLVWLVEMFTGWFAQTFLHQFIRGAWGLGFM
                     IFIAFPMGKELLEGEYHEHD"
     gene            complement(9875..10081)
                     /locus_tag="VW361_001781"
     CDS             complement(9875..10081)
                     /locus_tag="VW361_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744780.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDENFYHFPWEVFAG
                     FGMMSWLVREGLKLVRDVKKEFEK"
BASE COUNT         3273 a         2426 c         1908 g         3056 t
ORIGIN      
        1 aagccctatc tacgatactg tttcaagaaa cgagtcatct tttcttggat ttgggctaac
       61 tcatcaacac gaggaaggta aacgatacgg aagtggtctg gttcctgcca gttaaagcct
      121 cgaccatgaa ccaagagaac cttttcctgc ttcaagaaat caaggacaaa ctgctcatca
      181 tcatcgatac ggtacatatt gcggtcgatt tttgggaaga tatagagccc cgccttgggt
      241 ttaacggcag acaaacctgg aatatcttga atggcattat agatgaaatt tctttgctcg
      301 tagattcgtc caccaggaag aagcaattca tcgactgatt ggtgaccccc caaggaagtt
      361 tgtacgactt gttgggccaa aacgttagag caaaggcgca tattggacag catattgagc
      421 ccttcgatat agcccttaac atgagtctta gggccagaca agaccatcca acccacacgg
      481 aaacctgcta tgcggtggga ttttgacaga ccattcatgc tgacacagaa gacatctggt
      541 gccaagctcg ccacaggcgt atgcacatgt ccgtccatta ccatgcggtc atagatttca
      601 tccgcaaaga taatcaaatc gttttgacgg gcaatctcaa taatctccag caagagttcc
      661 ttaggataaa gggctccagt tgggttattt ggattgataa ggacaattgc cttggtattg
      721 gaagtgattt ttgacttgat atcgtcaata tctgggtacc attccacagc ttcatcacag
      781 atatagtgaa cggcatttcc tccagctagg ctgacagccg ccgtccatag aggatagtct
      841 ggcattggca ctaagacctc atccccattg tctaaaagcc cctgcatgga catgacaatc
      901 aactcactga caccatttcc aaggtaaata tcatcaatat ctacgtttgg gaatttcttc
      961 agctggcaat actgcatgat ggccttacgg gctgagaaaa tccctttgga gtcagaatag
     1021 ccttcactat cacgcgcatt cataatcaag tcatgaatga cctcgtctgg cgctgtaaag
     1081 ccaaattctg ctggatttcc tgtattcaga cgtaaaatct tttctccatt cgctcgcatc
     1141 cgcatggctt cttccaatac aggaccacgg atatcataag caacatgctc taacttacta
     1201 gacttgttat attctttcat cttgtttcct caattcatca ggatagtaac attataccac
     1261 tagaaagaga atgcgacaag tttactgaaa tgtgttacta gtttcgtata gaagaaaaac
     1321 cttgctaaag gcgaggttaa gaacgtagag atagcaggta ttttgcaaag acacatcaca
     1381 taccaaaaga taaacctaga aaaagcaagc ctagaaagga gtcataaaga agattaaaca
     1441 tgaggaaaag cccccatatc atcaagtaat cccaacgccc acttcgtttt gcaactagaa
     1501 ataagattag atggtagagt acatgaaaga ctaaaaatcc aataaaactt ggataaagaa
     1561 gcggtaccag actctctaat tgacagatca tgatcacttc taccaagact gaaactagga
     1621 taattccata ataaaggaaa tttgattttt gaaaagagtt tttcatcatt ctcccttcct
     1681 tcacttcttt cctgctatcc tttcttttat tttatcatat atttatatag agtttaagcc
     1741 ctaatattct tttgaaaaat actttttttg ctttacttct atagtgaaaa ggtttacaat
     1801 tatagtaaga aaatttcagg aggtttcatt atggcacaac gttaccaaaa tatcatggtc
     1861 gcaatcgatg gttctaagga agcggacttg gcttttgtca agggagttca ttctgctcta
     1921 cgaaacgacg ctaaactcac catcgcacat gtcattgaca cacgcgctct ccaaagcgta
     1981 tccacctttg atgctgaagt ttacgaagaa ctccaagtcg acgctgaaag tctgatgaaa
     2041 gagtacgaaa aacgtgctaa agatgctggg gtagcagatg ttcatatcgt cattgaaatg
     2101 ggaaatccaa agaccctgct agcacgtact attccagatg ccgaggaagt ggacctcatc
     2161 ctcgttggcg caactggtct caacgccttt gaacgcctct tggtcggctc ttcatctgaa
     2221 tacatactcc gccatgctaa ggtcgatttg ctggttgtga gagaacaaga aaaaacctta
     2281 taatcacaaa gaaaaggagc ccctagctcc tttttgttta cgatttattt ctctctttat
     2341 ggcgttcgta agccttgagc tggcgctgca gttccttttt aatagcaggt tctggagcat
     2401 atttttcttc ccaattatct ggttttaaga ttttatgggt cactggatca aaatgagcct
     2461 tgccatctgg aaaaattttc cccatattgg cctgatggac aatatcaaaa atacgttctg
     2521 ggtccacccc catcaagaca aaactgccgt aggtgaagta aagcgtgtca atcaaggcat
     2581 ccacttgccc tatcaaatct tgctgagcag gtgtcttctt ggctacttta cctgctgcct
     2641 tatcaagggc ctgatgaagt tgcgatacag cttgaccaaa atcttcttca gaaggactgg
     2701 ctgctcgaac aaactccacc aattcttcta ttttaaaacc agccctatgg gttgcaccct
     2761 ctaaatccca agctcgaggt tcttcttggg ttcgttcatc catcatgtgg tggaaggtct
     2821 tgaccttatt gaaatgatag tcacggctga caaagacttt ttctgaagac aaaacaccaa
     2881 aatgttccaa ggccttgtgg atcccatctt gttgattgct agtggtaatg tgcttggcag
     2941 cttccttgac actgctacta ccatttccca tagcgaccga cataccgacg ccagccagca
     3001 tttcaaggtc attatctgag tcaccaaaag ccatgacttg gttgaggtca aagccatatt
     3061 ctttcccaac tcggcgaatg ccttctaatt tagaatttcc ctgattgatg acatccgatg
     3121 caaaaggatt gctacgtgtc aatttcaagt cttcaaaatc agctgccgcc ttctcagatt
     3181 cttctggtgt catcagcatc aaaacttggt agataggctg attcatcagg tgaagcaggt
     3241 cctcttcctt ttggggaaca accttgctga ccatgcgatt aaaagactga ctcaccgtcc
     3301 gagttaaaac agagggaacg aagcgactaa ttcgttggga aaaagaaccc agaccaaagg
     3361 acatgatttt agaacccaac atggcatcct tggtccctag agcaatctcc gtgccctctt
     3421 ttttagcata gctaattaga tggcgcaaat gtaacttgga aatagggctc gtgaacaaga
     3481 ctctgtcttt actaaagata tactggccat tataggttac cgcaaaatcc agatccaaat
     3541 cgtccatcaa ttccttaaca aaaaaaggtc ctcgccctgt cgctacgcca actagtaccc
     3601 cttgttcttt gacaatctta atcgcgtcct tagtggattt caaaacactc ttgcgattgt
     3661 tgaccaaggt tccatcgata tcaaaaaaaa cagctttgac ttccatccta ttccaatctc
     3721 cccttttgtg atacaatgat tataccacat ttcagaaaga gttagtaaat catgcctaag
     3781 aaaatccttg ttttacatac gggtggaact atttccatgc aggccgatgc ttctggcgct
     3841 gttgtgacga gttcagataa tcccatgaac catgtgtcca acccacttga aggaatccaa
     3901 gtccacgcct tggacttttt taaccttcca agtccccata tcaaacccaa acatatgctg
     3961 gtcctctacc agaaaattaa agaggaagca gataactacg atggagtggt gatcacacac
     4021 ggaaccgata ctttagagga aacagcctat ttccttgata ccatggaagt tccccatatg
     4081 cctatcgttc taacaggagc catgcgtagc tccaatgagc tcggtagtga tggtgtttat
     4141 aattacctaa gtgctttacg agtggccagc gatgacaggg ctgctgacaa aggagttttg
     4201 gtcgttatga acgatgaaat ccacgctgcc aagtatgtca ccaaaacaca tacgactaat
     4261 gtcagcacct tccagactcc aacacatggc cccctcggtc tcatcatgaa acaggaaatc
     4321 ctctacttca aaacagctga acctcgtgtt cgctttgacc ttgatcacat acaaggttta
     4381 gtccctatca tctcggctta tgctggtatg acagatgagc tgattgatat gctggattta
     4441 gaacacttgg acggtttgat tatccaagcc ttcggagctg gtaatattcc caaagaaacg
     4501 gctcaaaaat tagaaagcct tctgcaaaaa ggaatcccag tcgctctggt atcacgatgc
     4561 tttaacggta ttgccgagcc tgtttatgcc taccagggtg ggggcgtaca gttgcaaaaa
     4621 gcaggcgttt tctttgttaa agaactcaac gcccaaaaag cccgcttgaa actcctcatc
     4681 gccctcaatg ccggactaac aggacaggct ttgaaagact atatggaagg ctaatactct
     4741 tcgaaaatct ctgcaaacca cgtcagcgtc gccttaccgt atgtatggtt actgacttcg
     4801 tcagtttcat ctgcaacctc aaaacagtgt gttgcgcagc ctttaaccag ccgcctagtc
     4861 cgctctatgg tattcattaa gtcaacatct cttgtttaag agcacaaaat caggaaatct
     4921 tctcgattcc ctgatttttt ctatttacgt tttcgtgttg agctacgttc tgtcaaacca
     4981 tgaggtaaga gaacttcacg ttcttccaac tcttccttat gcataatctt ggtcaacata
     5041 cgcatactaa tggcaccaag gtcataaaga ggttgggcaa tcgttgtcaa gtttggacgg
     5101 gtaaagcgtg agatttgtga atcatcacta gtaataattt caaaatcttc tggcacagaa
     5161 acacccttat cagccaaacc gttcaagact cctgctgcca actcatcacc tgtcacaact
     5221 gctgcagttg catttgatga aatcaaacgc tctgctaagg cgtaaccatc atcatagcta
     5281 tatttagatt caaataccaa accctcacta taagcgattc ctgctttttt caaggtttcc
     5341 ttgtagccaa ctaaacgaac cttaccattg atgtcatcca ctagcggacc gctaacgaaa
     5401 gcaatacgct cattttcttt agcaaggtaa ctcactgcat caattgttgc ttgcttatag
     5461 tcaatattga cacttggcaa ctggtgctca acatcgacag ttcctgcgag aacaatcgga
     5521 gtacgtgaac gcgaaaattc tgagcgaatt ttatctgtca agtgataacc catatagata
     5581 atgccatcta cctgctttga aaagagggta ttgacaacag aaacttcttt ctcgttatct
     5641 tcatcgctat tagctaggac aatattgtac ttgtacattt ctgcaatatc atcaatcccc
     5701 ttagccaaac tcgaaaaata accattggta atatttggaa tcacgacacc gacagtggtt
     5761 gtctttttac ttgcaagacc acgcgcaact gcatttggac gataatccaa acgatcaatt
     5821 acctctagca cttttttacg ggtattctct tttacatttt tattgccatt gaccacacgg
     5881 ctgaccgtcg ccatggaaac acctgcttca cgagcgacat cataaatggt tactgtatca
     5941 tctgcattca ttccttttcc tgtcctttct atctcacaca ttcttttaca agtagaggtg
     6001 ctgattgaag ctctatatct acttacaaaa gtgaagatgt gaaaatttcg ttttcatatt
     6061 tctacttatt ccattctatc actaattgta aacactttca agtgtttttt gaagattgat
     6121 tgaaaaaatt tcatagaaaa cctaggttta gctccttgct agcaccttag actaaacaaa
     6181 aaggaggaaa ctaagccctc ctaaagttat agtaaaatga aataagaaca ggataaatcg
     6241 atcaggacag tcaaatcgat ttctaacaat gttttagaag tagaggtgta ctattctagt
     6301 ttcaatctac tataggtatt gttccattca ctaccgtcaa ttttagcaca tagtcttcat
     6361 gaaaatatta tatcatcata accaaccaga ttcttttgcg atattagctg cctctgttcg
     6421 attaccagca tccagttttg aaagaatatt ggtgacatag tttcgaatag ttccgtttga
     6481 gaggtaaagc tgatctgcga tttcttggtt ggataagccc cgggcgattc cctttaagac
     6541 agcaatctct tgttctgtca acggattggg acgggtcatc accacttcca tcaattcagg
     6601 cgaatactcc ttgcgtcctt cgaggacggt gtgcaaggtt tgcatgaggt ctgcaatgct
     6661 tcgttccttt aatacataag catccactcc agccttgacc gcacgttcaa aatacccagc
     6721 acgcttgaag gtcgtcacca caaccacctt tgtttcaagc ttttctgatc gtatccactc
     6781 caagacttca agacctgtct taacaggcat ttctacgtca aggatggcga tatctacaga
     6841 ctccttttct aatagttgga ttgcttcttg cccattcttg gtttgaagga cagactccac
     6901 atctggttga agcgtgagca attgacacat ggcatctcgc aacatacttt gatcttctgc
     6961 gactaatact ttcatcttag tttctctcct tataaggtag tcgaacttgc acttccgttg
     7021 gatgtttctg actgattaca cttacttctc ctgaaaatgg aaaaacacga tctcggactg
     7081 tatggagctc atctcctttt agaaaagcaa agccgcagcc atcatcactt actgttaaaa
     7141 tgagttcctt ctctgtccgt tctaatttta agtaagcttt aaacgctttg gcatgtttga
     7201 tgatattggt caccaactca agcaaaatca tagcagccgt cgactccaca tcctgggtca
     7261 agctagcctt gtctaagtga ttctcaactt gaacctcaat tccagcaatt tctaacatct
     7321 ttttcacagt ctctagttcg gatgtcaaag ttctagactt aagattttcc acaatggttc
     7381 gcacttcatt catggaatcc ttgctgatct ggtgaatttc ttttaattcc ttttccacct
     7441 gtggataagc ctccatctga aataactgca aggctagatc agttttaaca ctaagcatag
     7501 caaaggtatg ccccagacta tcatgcaaat cttgaccgat acgattgcgt tcattttcag
     7561 caagcaatag atttatctgg gcattttgct tagcctgtgc ttctttcaaa tcctccacaa
     7621 ttcgaatccg aaccaagcca aaagtcatta aatcgacaaa agcaagaatt acaagtagat
     7681 agaatagaaa ctcaacttcg attctctgaa aaatcaacag ttgacccaca acaaggactt
     7741 gagcaagaag aaaagtccag acatgtaaag actttaaacc acctacgctg aaatgatagc
     7801 ttaagagatt ggataggaaa aagaaaaacc agatataatt aacagccaca aaggcagtat
     7861 tcccaactac ataagtcagc aggatgcccc aatatagcca agatagacgc tggctcttag
     7921 ttgttaaaac acccaaatac gccactacaa atagaatatc aatcaataaa tgccaggcag
     7981 aaagccaccc aatcactaca ggtaggatgg ggaaaaccat aaaaattaaa ctgatccaaa
     8041 acatataatg tatgcttttc agtctttcaa gcattaagca ttctccttat gaccttgaag
     8101 gtaaatggtc aaaccaaaca aaactactga aaaaacaagt aaataaactg tggctgatag
     8161 attgattcca ccttcattta agaaggtctt gattaattcc atcaactgat atgttggaag
     8221 acacttaccc actacttgca tccagtctgg aaataaagag ataggcatcc aaagtccacc
     8281 taaaacagcc aatcctagat aaagaagatt acccacgaca gacatcagct gactagtcgg
     8341 taagagagtc aaggtcaagc caagcgctac aaaagcaata cttcccacaa tcagcaaaat
     8401 cgcagctcca acccagcttg ctagagacat gtccacacct cttacaaaat gcccaactga
     8461 gaaaaccacc aagattgaaa ccaaataatc aaccagcata cttgttatct ttgatagata
     8521 atattctacc atatttacag ggctatgacg taatgttttc tgccagttgt tcatcttgtc
     8581 ggtatgtaaa acaactggaa atgagaagat agctgtcgac atcatagaaa aggcagtcat
     8641 ggagataaga taatcacgca taaaattcgc gggtccacct ggtgtatcct ggtacatgct
     8701 agaaaagaat agatagaagg ctgtcggcat ccctactgat aataaataat agactgattg
     8761 ccgtttggtc aatagaaatt ctatcttatt taatgctatc catcgtttca tcttagtcat
     8821 ctcccttttg tgtttcttca aagattgtat ccaacaagct acgattatta acttcaattt
     8881 cttgaatcct acatcctgct tgcactaaca gttgccaaaa agaatccgct tcacgtgtaa
     8941 ctacttgcag agcatcttgt ttttgtaccc agttttcaac caagactgac ttctcaacga
     9001 cttccttgta agctagagga aggataaaat gcttttcaat ctcctcacta cgcatagcta
     9061 gaggcgtcgt atcacgaatc aactctccct tatttaaaac caaaatccgg tcagctgtat
     9121 gttctacctc ttcaatataa tgagacgaat agagaatggt gactccttgc gcttttaggt
     9181 cccgaacaat ttcccaaaaa cgttgacggg tagaggtatc catggcagca gttggctcat
     9241 ctaaaaagac aagctttggt cgaccaatca aggtcaagac gaaagaaaag agacgctttt
     9301 gtccacctga taatttttct gcaaattgtt ctttctgttg ctggtcaaac tgcaatagtt
     9361 gatcgatttc ctgctcgctc aagggatttg ggtaaatgct ttgaaagaaa gcaatcaact
     9421 ctttgacctt taatttctgt acaatcacat tttcttgaga gaggtaagcc ctagtatagt
     9481 ctaacttaga actcgtcact ggtaaacctt gaatagatac ttgaccgctg gtgaccagtt
     9541 tatctccgag caaacagtcc aaaagtgtcg tcttaccagc accattaggg ccaatcaagg
     9601 caacgcattc accttctgct acttcaaagg aaatatcctt taaaatagcc ttgcccttaa
     9661 tatttttatg taatccttga accttaatca tgttcatgat attctccttc cagcaactcc
     9721 tttcccatcg gaaaggcgat aaaaatcata aatcctaatc cccatgcacc acggatgaac
     9781 tggtgaagga aggtttgagc aaaccaacct gtaaacattt ctaccagcca taccaagagt
     9841 gacaggccga taaagaaata gatagttgct tttttcattt ttcaaactcc tttttcacat
     9901 ctcttactaa tttcaaacct tctctgacaa gccaagacat cattccaaag ccagcaaaga
     9961 cctcccaagg aaaatggtag aaattctcat ccaatcccga aaacatgaga taggtcataa
    10021 ctcctgctac tactaaactt actgcgataa tcattttatt tctcatctct tcttccccca
    10081 tttcatacta caattatagt cttttaaaat cagaggaggc agaagcttct gtcactagaa
    10141 aatatgacaa atgtcataaa aaattctgtt caaaacaagc aagatacact gtacaataaa
    10201 acacaatcag aaaaatctaa ggcaacttcc tcaaaagaga tatcaaaccc aattcacacc
    10261 ataatgtaaa ctaatactta tttaaaatca aaaagagtag aaatttttat cagacaaaca
    10321 catatatagt gtattgaatc tataacagta gggcttaaat actaaaatat ttctataaat
    10381 taatttaact ttcctgatag agctgttcat atcttatttc aattctctat attatacgtt
    10441 gaacaaaacc cttctattgc tttcttaaaa atttataaga gttataaaat ctgttaaatt
    10501 tcaatgtgta tacctaaact acggtattta ttgaaaagac tggggacaaa aagtatacgc
    10561 tgccaaaatg aattactgaa aatcaaaaaa gagagaacca aactgattcc ctcttaatgt
    10621 atataatatc tagttttaaa aatacacact cacatatctc tgt
//
LOCUS       DAVKMO010000059        10064 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVKMO010000059 DAVKMO010000000
VERSION     DAVKMO010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10064
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.059"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            159..5069
                     /locus_tag="VW361_001782"
     CDS             159..5069
                     /locus_tag="VW361_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU9744781.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEAASAAKPEEKAGEVVAETPS
                     AEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKTLKPKEIKFNS
                     WEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSNTNSKAKDHAS
                     VGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLFFNWSNSIADQ
                     ERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLGEKMRQFMLYS
                     KEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPADNFFANFNWD
                     KAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGKLRLSLGLFAP
                     DTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADRTPAVGNTFTT
                     SFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAEYDFTDAYNGG
                     NSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAFSTTPDYKFDD
                     ADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNLGQLTISDNHQ
                     EPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKLLTGSSSTTIY
                     LPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLPKPLAENIVPG
                     ATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKPRTVVRWVMDH
                     AGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLDKPITAQDWRL
                     NVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQVGFADVPAGA
                     TITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGKEISNVLAVSV
                     PKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIRLTHAGVSVSG
                     FDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQEPKKDYLVGDSL
                     DLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLHYQGHEVSFDVLVSP
                     KAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEAFLKAIEAAEQVLKDHETSTQDQV
                     NDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLAAKPNHPSGSALAPLLEKNK
                     ALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSNKEKTVIKGLK
                     VERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEKDKKVKKVFFL
                     PEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNTVLPKPTYQPA
                     SDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVFEVDENGQRRL
                     RSTEVIQEAIPEIVEIGTKVKTVLAVVATQEKPAQNTAVKSEEASKQLPNTGTADANE
                     ALIAGLASLGLASLALTLRRKREDKD"
     gene            5159..6355
                     /locus_tag="VW361_001783"
     CDS             5159..6355
                     /locus_tag="VW361_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU9744782.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            6491..7018
                     /locus_tag="VW361_001784"
     CDS             6491..7018
                     /locus_tag="VW361_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9744783.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            7095..7451
                     /gene="glnR"
                     /locus_tag="VW361_001785"
     CDS             7095..7451
                     /gene="glnR"
                     /locus_tag="VW361_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU9744784.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            7488..8834
                     /gene="glnA"
                     /locus_tag="VW361_001786"
     CDS             7488..8834
                     /gene="glnA"
                     /locus_tag="VW361_001786"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU9744785.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(8924..9043)
                     /locus_tag="VW361_001787"
     CDS             complement(8924..9043)
                     /locus_tag="VW361_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU9744786.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            9531..10064
                     /locus_tag="VW361_001788"
                     /pseudo
     CDS             9531..10064
                     /locus_tag="VW361_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3242 a         1809 c         2185 g         2828 t
ORIGIN      
        1 ttaaccttat tttagatttg tgcaaacagt tattgttttt tgtctaaaaa tgttttagga
       61 taaaaatgtg attatcatgg ttctagagtt tgataaaaaa ctacagaata taaagcgctt
      121 tctttaaaac aacaaaatca atcttttagg aggagaaaat gaagaatcca ttttttgaaa
      181 gacgttgtcg ttacagtatt cgtaagttat cagtaggagc ctgctcgctg atgattggtg
      241 ctgttttatt tgctggtcca gccttggctg aagaaactgc agttcctgaa aatagcggag
      301 ctaatacaga gcttgtttca ggagagagtg agcattcgac caatgaagct gataagcaga
      361 atgaagggga acatgctaga gaaaacaagc tagaaaaggc agaagcagct agcgcagcta
      421 aaccagagga aaaagcaggt gaggtggttg cagaaacacc atctgcagaa gcaaaaccta
      481 agtctgacaa ggaaacagaa gcaaagcccg aagcaactaa ccaaggggat gagtctaagc
      541 cagcagcaga agctaataag actgaaaaag aagtccagcc agatgtccct aaaaatacag
      601 aaaaaacatt aaaaccaaag gaaatcaaat ttaattcttg ggaagaattg ttaaaatggg
      661 aaccaggtgc tcgtgaagat gatgctatta accgcggatc tgttgtcctc gcttcacgtc
      721 ggacaggtca tttagtcaat gaaaaagcta gcaaggaagc aaaagttcaa gccttatcaa
      781 acaccaattc taaagcaaaa gaccatgctt ctgttggtgg agaagagttc aaggcctatg
      841 cttttgacta ttggcaatat ctagattcaa tggtcttctg ggaaggtctc gtaccaactc
      901 ctgacgttat tgatgcaggt caccgtaacg gggttcctgt atacggtaca ctcttcttca
      961 actggtctaa tagtattgca gatcaagaaa gatttgctga agctttgaag caagacgcag
     1021 atggtagctt cccaattgcc cgtaaattgg tagacatggc caagtattat ggctatgatg
     1081 gctatttcat caaccaagaa acaactggag atttggttaa acctcttgga gaaaagatgc
     1141 gccagtttat gctctatagc aaggaatatg ctgctaaggt aaaccatcca atcaagtatt
     1201 cttggtatga tgccatgacc tataactatg gacgttacca tcaagatggt ttgggagaat
     1261 acaactacca attcatgcaa ccagaaggag ataaggttcc ggcagataac ttctttgcta
     1321 actttaactg ggataaggct aaaaatgatt acactattgc aactgccaac tggattggtc
     1381 gtaatcctta tgatgtattt gcaggtttgg aattgcaaca gggtggttcc tacaagacaa
     1441 aggttaagtg gaatgacatt ttagacgaaa atgggaaatt gcgcctttct cttggtttat
     1501 ttgccccaga taccattaca agtttaggaa aaactggtga agattatcat aaaaatgaag
     1561 atatcttctt tacaggttat caaggagacc ccactggcca aaaaccaggt gacaaagatt
     1621 ggtatggtat tgctaaccta gttgcggacc gtacgccagc ggtaggtaat acttttacta
     1681 cttcttttaa tacaggtcat ggtaaaaaat ggttcgtaga tggtaaggtt tctaaggatt
     1741 ctgagtggaa ttatcgttca gtatcaggtg ttcttccaac atggcgctgg tggcagactt
     1801 caacagggga aaaacttcgt gcagaatatg attttacaga tgcctataat ggcggaaatt
     1861 cccttaaatt ctctggtgat gtagctggta agacagatca ggatgtgaga ctttattcta
     1921 ctaagttaga agtaactgag aagaccaaac ttcgtgttgc ccacaaggga ggaaaaggtt
     1981 ctaaagttta tatggcattc tctacaactc cagactacaa attcgatgat gcagatgcat
     2041 ggaaagagct aaccctttct gacaactgga caaatgaaga atttgatctc agctcactag
     2101 cgggtaaaac catctatgca gtcaaactat ttttcgagca tgaaggtgct gtaaaagatt
     2161 atcagttcaa cctcggacaa ttaactatct cggacaatca ccaagagcca caatcgccga
     2221 caagcttttc tgtagtgaaa caatctctta aaaatgccca agaagcggaa gcagttgtgc
     2281 aatttaaagg caacaaggat gcagatttct atgaagttta tgaaaaagat ggagacagct
     2341 ggaaattact aactggctca tcttctacaa ctatttatct accaaaagtt agccgctcag
     2401 caagtgctca gggtacaact caagaactga aggttgtagc agtcggtaaa aatggagttc
     2461 gttcagaagc tgcaaccaca acctttgatt ggggtatgac tgtaaaagat accagcctac
     2521 caaaaccact agctgaaaat atcgttccag gtgcaacagt tattgatagt actttcccta
     2581 agactgaagg tggagaaggt attgaaggta tgttgaacgg taccattact agcttgtcag
     2641 ataaatggtc ttcagctcag ttgagtggta gtgtggatat tcgtttgacc aagccacgta
     2701 ccgttgttag atgggtcatg gatcatgcag gggctggtgg tgagtctgtt aacgatggct
     2761 tgatgaacac caaagacttt gacctttatt ataaagatgc agatggtgag tggaagctag
     2821 ctaaggaagt ccgtggtaac aaagcacacg tgacagatat cactcttgat aaaccaatca
     2881 ctgctcaaga ctggcgcttg aatgttgtca cttctgacaa tggaactcca tggaaggcta
     2941 ttcgtatcta taactggaaa atgtatgaaa agcttgatac tgagagtgtc aatattccga
     3001 tggccaaggc tgcagcccgt tctctaggca ataacaaggt acaagttggc tttgcagatg
     3061 taccggctgg agcaactatt accgtttatg ataatccaaa ttctcaaact ccgcttgcaa
     3121 ccttgaagag cgaagttgga ggagacctag caagtgcacc attggatttg acaaatcaat
     3181 ctggtcttct ttattatcgt acccagttgc caggcaagga aattagtaat gtcctagcag
     3241 tttccgttcc aaaagatgac agaagaatca agtcagtcag cctagaaaca ggacctaaga
     3301 aaacaagcta cgccgaaggg gaggatttgg accttagagg tggtgttctt cgagttcagt
     3361 atgaaggagg aactgaggac gaactcattc gcctaactca cgcaggtgta tcagtatcag
     3421 gttttgatac gcatcataag ggagaacaga atcttactct ccaatatttg ggacaaccgg
     3481 taaatgctaa tttgtcagtg actgtcactg gccaagacga agcaagtccg aaaactattt
     3541 tgggaattga agtaagtcag gaaccgaaaa aagattacct agttggtgat agcttagact
     3601 tgtctgaagg acgctttgca gtggcttata gcaatgacac catggaagaa cattccttta
     3661 ctgatgaggg agttgaaatt tctggttacg atgctcaaaa gactggtcgt caaaccttga
     3721 cgcttcatta ccaaggccat gaagttagct ttgatgtttt ggtatctcca aaagcagcat
     3781 tgaacgatga gtacctcaaa caaaaattag cagaagttga agctgctaag aacaaggtgg
     3841 tctataactt tgcttcatca gaagtaaaag aagccttctt gaaagcaatt gaagcggccg
     3901 aacaagtgtt gaaagaccat gaaactagca cccaagatca agtcaatgac cgacttaata
     3961 aattgacaga agctcataaa gctctgaatg gtcaagagaa atttaaggaa gaaaagacag
     4021 agcttgatcg tttaacaggt gaggttcaag aactcttggc tgccaaacca aaccatcctt
     4081 caggttctgc cctagctccg cttcttgaga aaaacaaggc cttggttgaa aaagtagatt
     4141 tgagtccaga agagcttgca acagcgaaac agagtctaaa agatctggtt gctttattga
     4201 aagaagacaa gccagcagtc ttttctgata gtaaaacagg tgttgaagta cacttctcaa
     4261 ataaagagaa gactgtcatc aagggtttga aagtagagcg tgttcaagca agtgctgaag
     4321 agaagaaata ctttgctgga gaagatgctc atgtctttga aatagaaggt ttggatgaaa
     4381 aaggtcaaga tgttgatctc tcttatgctt ctattgtgaa aatcccaatt gaaaaagata
     4441 agaaagttaa gaaagtattt ttcttacctg aaggcaaaga ggcagtagaa ttggcttttg
     4501 aacaaacgga tagtcatgtt atctttacag cacctcactt tactcattat gcctttgttt
     4561 atgaatctgc tgaaaaacca caacctgcta aaccagcacc acaaaacaca gtccttccaa
     4621 aacctactta tcaaccggct tctgatcaac aaaaggctcc taaattggaa gttcaagagg
     4681 aaaaggttgc ctttcatcgt caagagcatg aaaatgctga gatgctagtt ggggaacaac
     4741 gagtcatcat acagggacga gatggactgt taagacatgt ctttgaagtt gatgaaaacg
     4801 gtcagcgtcg tcttcgttca acagaagtca tccaagaagc gattccagaa attgttgaaa
     4861 ttggaacaaa agtaaaaaca gtactagcag tagtagctac acaggaaaaa ccagctcaaa
     4921 atacagcagt taaatcagaa gaagcaagca aacaattgcc aaatacagga acagctgatg
     4981 ctaatgaagc cctaatagca ggcttagcca gccttggtct tgctagttta gccttgacct
     5041 tgagacggaa aagagaagat aaagattaaa tatcgaaaaa tcttgtgaaa tctttcctta
     5101 tatttccaaa gtgtgatata atagtttcga ataaaataaa taaaggagtt tttgtaacat
     5161 ggcaaaactt actgttaaag acgttgactt gaaaggtaaa aaagtcctcg ttcgtgttga
     5221 cttcaacgta ccattgaaag atggcgtaat cactaacgat aaccgtatca cagcagctct
     5281 tccaactatt aagtacatca tcgaacaagg tggacgtgca attcttttct ctcaccttgg
     5341 acgtgtgaaa gaagaagctg ataaagctgg taaatcactt gctcctgtag cagctgactt
     5401 ggcagcaaaa cttggtcaag atgttgtttt cccaggtgtc actcgtggtg ctgaattgga
     5461 agcggcaatc aacgctcttg aagatggaca agttctcttg gttgaaaaca ctcgttacga
     5521 agatgttgac ggcaagaaag aatctaaaaa cgatcctgaa cttggtaaat actgggcatc
     5581 acttggagat ggtatcttcg taaacgatgc attcggtaca gctcaccgtg cacacgcatc
     5641 taatgttggt atctcagcaa acgttgaaaa agcagttgct ggtttccttc ttgaaaatga
     5701 aattgcctac atccaagaag cagttgaaac tccagaacgt ccattcgtgg ctatccttgg
     5761 tggttcaaaa gtttcagaca agatcggtgt tatcgaaaac ttgcttgaaa aagctgataa
     5821 agtccttatc ggtggtggga tgacttacac attctacaaa gcacaaggta tcgaaatcgg
     5881 taactcactt gtagaagaag acaaattgga tgttgcgaaa gctcttcttg aaaaagcaaa
     5941 tggtaaattg atcttgccag ttgactcaaa agaagctaac gcatttgctg gttacactga
     6001 agtgcgtgac actgaaggtg aagcagtttc tgaaggcttc cttggtcttg acatcggtcc
     6061 aaaatctatc gccaaatttg acgaagcttt gactggtgcc aaaacagttg tatggaacgg
     6121 acctatgggt gtatttgaaa acccagattt ccaagctggt acaatcggtg tgatggacgc
     6181 tatcgtgaaa caaccaggag ttaaatcaat catcggtggt ggtgactcag ctgccgcagc
     6241 gattaacctt ggccgtgcag acaagttctc atggattagt acgggtggtg gagcatcaat
     6301 ggaacttctt gaaggtaagg ttcttccagg acttgcagcc ttgacagaaa aataagattt
     6361 tataaacaaa tcaaagaaga gagggatgaa agttcctctt ttcttttgct taaaataaaa
     6421 acgcttcctc tcaactatta ctcataaaaa tcaccgattt atgataaaat ggaaatagaa
     6481 agttgagatt atgagttatt ttaaaaaata taaattcgat aaatcccagt tcaaacttgg
     6541 tatgcgaacc tttaaaacag gtattgctgt ttttctagtt ctcttgattt ttggcttttt
     6601 tggctggaaa ggtcttcaaa ttggtgcttt gacagccgtt tttagcctga gggagagttt
     6661 tgatgagagt gttcattttg ggacttcgcg tattctagga aatagtatcg gtggactcta
     6721 tgccttggtc ttcttcttat taaatacctt tttccacgaa gccttttggg tgaccttggt
     6781 agttgttcca atctgcacca tgttaaccat tatgacaaat gtagccatga ataacaaagc
     6841 aggggttatt ggtggtgtag cagctatgtt aatcattacc ctatcaattc caagtggtga
     6901 gacaatttcg tacgtgtttg tgcgtgtatc agaaacgttt atgggagttt ttgtcgcaat
     6961 tatcgtaaat tacgatattg atcgtattcg tctcttttta gagaaaaaag aaaaataatg
     7021 ttacatttta taacattatc aattgacgtt tgtctttttt tagactataa tagacagaaa
     7081 gaaggaaatt gtaaatgaag gaaaaagaat ttcgccgaaa tatggctgtt tttcctatcg
     7141 gcagtgttat gaagttgacc gatctatcgg cgcgtcagat tcgttattat gaagatcaag
     7201 agttgatcaa gcccgatcga aacgaaggaa atcgtcgcat gtattccttg aatgacatgg
     7261 atcgtctgct tgaaatcaaa gattatatct ctgaaggtta taatatcgct gccattaaga
     7321 aaaaatatgc tgaacgtgaa gcgaaatcca agaaagcggt tagtcagact gaagtacgtc
     7381 gtgcacttca caatgaactc ctccaacagg ggcgttttgc ttcagtacag tcaccttttg
     7441 gtcgcggtta ggcaaccgca agtagtcata gattaaggag aaaacttatg ccaatcacag
     7501 ctgcagatat tcgtcgtgaa gtcaaggaaa aaaatgttac ctttattcgt cttatgttct
     7561 cagatatttt gggaaccatg aaaaacgtcg aaattcctgc tacagatgaa cagttagata
     7621 aggtcttgtc gaacaaggtt atgtttgatg gatcttctat tgaaggtttt gtacgtatca
     7681 atgagtcgga tatgtacttg tacccggact tggatacatg gacagtcttc ccttggggag
     7741 atgaaaatgg aagtgttgca ggtctgatct gtgatgtcta tacaacagaa ggtgaaccat
     7801 ttgcgggtga ccctcgtggt aatttgaaac gagctcttcg tcacatggaa gaagttggat
     7861 tcaaatcctt caaccttggt ccagagccag aattcttcct atttaagttg gatgaaaatg
     7921 gggacccaac acttgaagtg aatgacaagg gtggctactt tgatttggca cctactgacc
     7981 ttgcggacaa cacacgtcgt gagattgtga atgtcttgac caaaatggga tttgaagtag
     8041 aagcgagtca ccacgaggtt gcggttggac agcatgagat tgactttaag tacgatgaag
     8101 ttctccgtgc ttgtgataag attcaaatct ttaaacttgt tgttaaaacc attgctcgca
     8161 aacacggact ttacgcaaca tttatggcga agccaaaatt tggtattgct ggctcaggta
     8221 tgcactgtaa tatgtccttg tttgatgcag aaggaaataa cgccttcttt gatccaaatg
     8281 atccaaaagg aatgcagttg tcagaaacag cttaccattt cctaggcggt ttgatcaagc
     8341 atgcttacaa ctatactgcc atcatgaacc caacagttaa ctcatacaaa cgtttggttc
     8401 caggttatga agcgcctgtt tacattgctt gggctggtcg taaccgttcg ccacttgtgc
     8461 gcgtacctgc ttcacgtggt atgggaactc gtcttgagtt gcgttcagtg gatccaatgg
     8521 cgaaccctta cattgctatg gctgttcttt tggaagttgg tttgtatggt attgaaaata
     8581 aaatcgaagc accagctcct atcgaagaaa atatctacat catgacagca gaagagcgca
     8641 aggaagctgg tattacagac cttccatcaa ctcttcataa tgctttgaaa gctttgacag
     8701 aagatgaagt ggttaaagct gctctcggag atcacatcta cactagcttc cttgaagcca
     8761 aacgaatcga atgggcaagt tatgcaacct tcgtttcaca atgggaaatt gataattatt
     8821 tagaccttta ctaatataga agaaagattg cctgtgggta aacagtcaca cagcagtcta
     8881 agccatcaaa tacctataac ccttaaaata gcgatttcgg tcgctattta tttttcgaaa
     8941 aatcctcttg actcttttgc gaattagatt tatcatcaga cgtgtagaag aaaatcaagg
     9001 agtcactatg gaaaaattca atttcaaaaa caatatcggg caagaaaaca agttacttca
     9061 aatcgaaatc tacaagttta ctaacttttg caagcttcaa aattacacat ctgtaaatat
     9121 tttttcgaaa gatatatttg aagccatagt aaattgagac tagaatagta cactacatct
     9181 gctaaaaatt tctagaaatt aatttaactt tcctaatcga tttgtttaca tcttatttca
     9241 atctactata ttatctcaat aaatgatgat ggcgactgtt ttgtttgtgc ttgtcgattt
     9301 ttgaatcctg atcgagcgga agaatatttc tgccgaggtt gtcaagggga aaatcctgaa
     9361 gatattgaat tttatgatga acaattacag gcagaaaagg tggaggcttt gaatattcga
     9421 ttggaagtaa aaaattgaat tatctacaat ctcatcaaca ataaacctat ttcaacccca
     9481 ttatctatag gcgtattttt acgccttttt atatacttga agcacataag aaacattatg
     9541 ggaagtttgc tgatggaagc actcaagaaa ttgatgttcc ttatgatatt cctgatactt
     9601 gggagtgggt gaggttttct acattggttg aaattgtcag aggtggctct ccacgaccaa
     9661 tcaaagatta tcttacttct gaagtagatg gaataaattg gataaaaata ggtgatactg
     9721 aaaagggtga aaagtatata aataatgtta aagaaaaaat caaaaaatca gggcttaaca
     9781 aaactagatt tgtaaaaaaa ggtacatttt tgttaactaa ttctatgagt tttggtagac
     9841 cttatatttt gaatgttgat ggtgcaatac acgatggatg gttggctatt tcgaactatg
     9901 aaaactcatt aaataaagat tacctattct atattctttc atcaaatgta gtttattctc
     9961 aatttctatc tctaattagt ggagctgttg tgaaaaactt gaatagtgat aaagttgctt
    10021 ctattcttat ccctctccct ccgctagctg aacaacaacg cata
//
LOCUS       DAVKMO010000060         9805 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVKMO010000060 DAVKMO010000000
VERSION     DAVKMO010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9805
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.060"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            5..208
                     /locus_tag="VW361_001789"
     CDS             5..208
                     /locus_tag="VW361_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU9744787.1"
                     /translation="MHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTVLPDI
                     KIKLPIDSRGTPDWNYMERYRDR"
     gene            174..488
                     /locus_tag="VW361_001790"
     CDS             174..488
                     /locus_tag="VW361_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744788.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            1173..1334
                     /locus_tag="VW361_001791"
     CDS             1173..1334
                     /locus_tag="VW361_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744789.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1426..1910
                     /locus_tag="VW361_001792"
                     /pseudo
     CDS             1426..1910
                     /locus_tag="VW361_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861739.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            1944..3104
                     /locus_tag="VW361_001793"
     CDS             1944..3104
                     /locus_tag="VW361_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU9744790.1"
                     /translation="MFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQN
                     GKNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEA
                     IVSDEVWQAAQVKLKSQAKRYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKK
                     DGTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQE
                     KINMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLY
                     RMYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISA
                     LISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3372..3938
                     /locus_tag="VW361_001794"
     CDS             3372..3938
                     /locus_tag="VW361_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744791.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4260..4448
                     /locus_tag="VW361_001795"
     CDS             4260..4448
                     /locus_tag="VW361_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU9744792.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4510..5268
                     /locus_tag="VW361_001796"
     CDS             4510..5268
                     /locus_tag="VW361_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9744793.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     ISEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            5326..6180
                     /locus_tag="VW361_001797"
     CDS             5326..6180
                     /locus_tag="VW361_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU9744794.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            6292..7176
                     /locus_tag="VW361_001798"
     CDS             6292..7176
                     /locus_tag="VW361_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU9744795.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7339..9078
                     /locus_tag="VW361_001799"
     CDS             7339..9078
                     /locus_tag="VW361_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEU9744796.1"
                     /translation="MELSAIYHRPESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGEFMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            9353..>9805
                     /locus_tag="VW361_001800"
     CDS             9353..>9805
                     /locus_tag="VW361_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744797.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
BASE COUNT         3522 a         1353 c         2047 g         2883 t
ORIGIN      
        1 gaaaattcat tgtttaaaat taaaaaataa agaattgaat aaagaagtag cattctattt
       61 aacttcaatt attaggcaag ctttaaaaaa tactgaatat aaagatcaaa tatctagcac
      121 agtattgcca gatatcaaaa ttaaattacc gatagacagt agaggtactc cagattggaa
      181 ttacatggaa agatatagag atagataaag agagagaggg agagatagat aaaaagtcca
      241 cccccatttt ttatggagaa ttcaaaaatg taaggttaag caaagaagaa tataaaaatc
      301 taaaagaaaa attaaactca cacacagata taatgataaa taaactatcc agatacatgg
      361 aaagcagtgg taagacctat caaaaccact atgtgacaat cttaaaatgg tatgaagaag
      421 ataaagacaa actaagacag aaaggtttaa ataaaaaaat gaattatgat gtaggagaat
      481 ctttatagat aaaaagaggt ggaaaggcac tattaaagac tttaagtcta aaaaggtatc
      541 aaagtatgcc agagataaaa aaaatataaa tatgacactt taaaggcgat tagaaaatta
      601 aagaaatgct agaagacttt tagatgacag ttaccaagag ggtctaattt tcactgctat
      661 ttatgcagtg ggaattggac ctttttatat aagcaaattc tatttcaaaa ttggttacca
      721 agaaagactt cttttcactg ttaagtataa gagggtaatt tatagaattt tgttacatca
      781 agataaatat tttctgatgg tcaaatttta aaaagattaa taactctcga taaattttga
      841 accttaacaa ttgaatagac caagacaaga cgttaattat ttttggagcg taataaccta
      901 tccgtcaaga tctttcggct gaataattcg gcaaaaaaag ttctgctaag caaaaagaaa
      961 gtgagcgata agtaagagtt tgaatatagg gagggatacc ctatccgcta tgaagaaaat
     1021 gagggtaatg atacttctaa ggttgaagcc ggctcatccg gaatagaggc ggaagtgaga
     1081 ttcctatgtt gctaatccaa agcacttgtc aatgtcaaaa aacttaatta aacaaataat
     1141 tattagatat aaaactttag aggaggtata tattggacaa tgactggaat ggattggctg
     1201 atttaatagc aaatctgatt gcaaaatatg ctggtgcttt agatttagat aatctacccg
     1261 atccaacgcc agcaaaaaat caagagatga aaaatagttt tgacatggca aaaacacaaa
     1321 ttgagacgga ctaataaaag tgttataata tacttgaaat gatagtccaa acttaaatta
     1381 aaaaaattat atatgatata gaaaaattat attgaggtta atactatgtc aaaagaaaaa
     1441 ataaaagtat acctctatac acgagtatct acgtcaatac agatagaggg gtattcgtta
     1501 gaggcacaaa aatcacgaat gaaagctttt gctatttaca acgattatga aattgttgga
     1561 gagtatgaag atgccgggaa gtctggcaag tctattgaag gtagaataca gttcaatcga
     1621 atgatggaag atataaaatc tggaaaagat ggagtatctt ttgttcttgt gtttaagtta
     1681 tcaagatttg caagaaatgc cgctgatgtt ctttctacac ttcagataat gcaggattat
     1741 ggagttaatc ttatctgcgt tgaagatggc attgattcat ctaaagatgc tgggaaacta
     1801 atgatttctg ttttatcagc tgtggctgaa atagaaagag aaaacatccg tattcaaaca
     1861 atggaaggtc gcattcaaag gcaagggaag gaaaatggaa tggtggcttt gctccgtatg
     1921 gatataaact tgaagacggc aagctgttta taaatgagga agaggcagtt gcaataagaa
     1981 cgattttcga ccagtatgta aatactacga taggagccaa tgggatatct aaatacttag
     2041 agaatcatgg aattagaaaa atcccaagac agaatggtaa gaatcctttg tttgatgcag
     2101 gtcttataag aaagatatta aagaatcctg tatataatgg gaaaatagca tttggaagaa
     2161 gaactttaga aaaagttcat ggtacaagaa atgaatataa gcaggttgaa caagatgaat
     2221 atctaatatc tgaagggata catgaagcta tagtttccga tgaagtttgg caagctgctc
     2281 aggttaagct aaaatctcaa gcaaagagat atgagcatgt gaataaagga aaagatacac
     2341 gcacacactt gctttctgga attgtaaaat gcccgatatg tggagtggga atgtttggga
     2401 acaagtgtat caagaaaaag aaagatggca caaagtataa agatttttat tactatggtt
     2461 gtaaacatag gcagatgata agaggtcata agtgtacatt cagtaagcaa attagagaag
     2521 aattgttaga tgatgctgtt gcagaggtga ttgtcaagat agtaagtaat ccgaaatttg
     2581 cttctatgat gcaagaaaaa atcaacatga aggtggatac ctctgaaata gaaaaagaaa
     2641 tagataatta ccaaaaggaa ttgagaaaga gtcattctac aaagtttaag ctaattgagg
     2701 aaatagataa tttagatgtt gaagataagc attataagag aaggaaacag gatttagatg
     2761 atagactata tcgtatgtat gacaaaatag atgaattaga atcatcacta attgatgcga
     2821 aagcaaagaa acagactatt gaagctgaaa agcttacagg agataacata tataaggttt
     2881 tgatctattt tgataagctc tataaagtca tgaatgatgt agagcgtagg cagttaattt
     2941 cagctttgat ttctgaaatt caagtttatg aagaaaaaca atctaacgga caatggctaa
     3001 aatccattac ttttaagcta ccaattatag aagaaaatct caacatagat ttggacaatg
     3061 atgaacaagt tgaatgtgta agtttattag agaaacgtag ttaatcctca aaaggttccc
     3121 caaacctttt gagtcccact gacgcatcac gctgaggcgg tatcactgct tgtacgagtt
     3181 gaagcatcag cgaagtaaaa gtagatgttc agccaatgcg acgaggtgag accgaaggtc
     3241 gataaggtgt gttctgggta taggactcgt aaagtaagta ggaaatatga tgagatgata
     3301 cagagagcct gaattggtca ggtgacgtgc ttatttacat tagcctgata atgaaaatgg
     3361 agagattatt gatggttata ttggaattgt accaaaatga ttattctaaa gatttagtag
     3421 catttgattc catagaagat gggaaagcct ttgtagctca aatcccggga tacactctgg
     3481 aaacagaaga tggttttgaa gtggagtatt ttaatcctaa aaacataccg gattatatgg
     3541 aaattatttt taacggaaat attgttcctt tatctaaatt tatgttcgat cctgaggaaa
     3601 atgtaaacat tatttggaaa gagatttcaa atttatccct caaaaatgat agagtgatcg
     3661 aaggatattc aaaaattgat gcatatgtcg ttaacaacca tgaagttaaa gcctatgtcg
     3721 aaacaagaga aacgaactat cgtaaagcaa aagacttctt agaaagccgc ggatatgaaa
     3781 tcgacagaag ctttttcgga agtgaagacg gtgaagcgat tctttacaga aaaaaaggga
     3841 tcgaagtttg gcatttcttg tgtcacttag acccaatgtt tgtagagatt gaagatgtag
     3901 aaggatatgt taaagaagaa gttggagaga ttcaatagtc aaccaaagtt ccttgtgagt
     3961 atataccttt gctagtaaaa gagtcaaaac gttataacga aggggggtaa gaaaaccctt
     4021 gagtgtaagt ctttttcttg tttagaggga aagtattaga gtagccgctc ataatttata
     4081 ctagatttga taactgattt gagacagatt ttatttctat aaatattgtg aaaatttttt
     4141 aataccaaag atttaaagtt actgtgttaa aaatcctctc cacttttaaa ctaatgtatt
     4201 ataaaagcca gttgacacaa gtgttacacc tgtgatagaa ttaacttgag gtgatgaaaa
     4261 tggcaaccga taaaaataga ataatgatta gcttggatga taaaaatcta gagaaacttg
     4321 aaaatttagt agaagatgct agagatagaa ggggaatgcg actaacaaag tcccaggtta
     4381 ttgaattact cctaaatacc gttgattatt tcgatgatat tatgggggct atttactcaa
     4441 aaaaataaga gcaaaattgc tattattttt tacaaattgg tgtaacacta gtgatatagg
     4501 agtgatgaaa tggttgttta tattagacaa agtaaattac caagtgaggt ttcaattaat
     4561 aaatacaatg ctcaagtagg tgcctactta caaggagaag aagttatttt atatcaatct
     4621 ttttctgaaa taaaagagtt aataagtgaa gatatagttg tagattatat aatggagact
     4681 agagcattac taaaaatgat gggcttaaac gttccggttt atgactatcc tattgagctt
     4741 aaagagtttt atggtcgaaa gatttatgct ggtattttag gagagattgt gaatatacct
     4801 gataattggg gaaaatttat taagcctaaa gctggttcaa aagtctttac tggaagagtt
     4861 gttaatggaa cccatgattt aataggtatt ggtctacctt tcgactatcc tatatggatt
     4921 agtgaggttg tagaattcat agctgaatgg cgttgttttg tgttagatgg tcgcgtatta
     4981 gatgttcgac cctatacagg tgattatcat gcacaatttg atgcaagtgt aattgatgaa
     5041 gcgatatcat gttggaaaga tgcgccaata gcttatggac tagatatcgg tgttactcgc
     5101 gatggcagaa cacttgttgt tgaagtaaat gatggttatg cattgggaaa ttatggccta
     5161 tctcctttaa aatcaatcaa ttttcataga gctaggtgga aagaaatggt aaaaccctat
     5221 tttgaaaaaa atgaaatttt taaaatccaa caggatgtta ttttctaaaa taaatatggt
     5281 agataaccaa tataaaaagc atcaaaatga acaaggagga atctgatgct tggagcaatt
     5341 attggagata ttgtcggttc tgtttacgaa tggaacaata tcaaaacaaa ggactttcct
     5401 ttatttcgga aggactgctt ttttacagat gacacggtta tgacctgtgc tgttgcagaa
     5461 gcaattatga atggtggaca aaaagacgat ttcattgacg cgatgaagaa atatggcaga
     5521 atgtatccga atgctgatta cggtgctcgg tttaatgcat ggctaaacag cgataaccgt
     5581 gagccttata atagctttgg gaatggatca gctatgcgta tttctccatg tgcttggatc
     5641 atggactgtg gtttttatgc gaaaactggt atgtggccat catctagagg acttacgagt
     5701 ctttctgcag aggtaactca taatcatcca gaaggtgtca aaggcgctat ggctacagct
     5761 gatgctatct ttctatgtcg tttttacttt ggtggttatt gtagagagta cgagcaatca
     5821 attaacgaca atcctacaga gtgtaaaaga cgaattaagg attatataga aaaagaatac
     5881 gattacaatt tatctcaaac tttagatgaa atccgtccta actatcgttt taacgaaaca
     5941 tgtcaggaaa ctgtccctca agctattatc gcctttcttg aaagtagaga cttcgaagat
     6001 gcgataagaa atgccatctc acttggtggc gacagtgata ctctcgcagc aatcacttgt
     6061 aacatagcag aggcagctta cggtattcct gattggatca aggataaggc ctattcttac
     6121 ttggatgaac ccttaaagga tgtagttagg cgatgggaaa atagaataaa agcgtattaa
     6181 tctccagtac gtcagatttc tcttttctgt attttcattg tataatagga ttacatttac
     6241 ttgcatacga cgaaatgtaa acatttctgt ttaaaattaa ggataaaatc aatgaaaaaa
     6301 gcaatggtaa ttatcaaccc tacttctggt ggcgagaagg ctttggatta caaagaaaag
     6361 ctggagaata aagcaaaaga atactttgaa tatgttgaaa ccaaaattac cgaaaaagcg
     6421 ctggatgcaa cacattttgc tgaagaagct tctcgtgagc agtatgatgc agtggttgtg
     6481 tttggtggag atggaactgt caatgaagtc atttcaggta ttgatgagag agactacatt
     6541 cctaagttag ggattatccc aggcggtacg ggtaacctca ttacaaaact tttggaaatc
     6601 aatcaagaca tcgatggcgc aattgacgaa ctggattttg atttaaccaa taagattgat
     6661 atcggtaaag caaatgacaa ctattttggt tatatcttta gtatcggttc tctgcctgag
     6721 gcgattcaca atgttgaaat agaggacaaa acaaaattcg gtattttaac ctatgctgta
     6781 aataccatga agtctgtcat gacagatcag gtctttaaca ttaaggttga gacagaaaat
     6841 ggaaattatg ttggtgaagc tagccatgtt ttggtccttt tgacaaatta cttcgctgat
     6901 aagaaaatct ttgaagaaaa caaggacggc tatgccaaca ttttgattct gaaagatgcc
     6961 tctatattct ccaaattatc cgtcattcct gatttattaa aaggggatgt tgtcgcaaat
     7021 gataatatcg agtatatcaa agcgcgtaat attaaaatct cttcagatag tgaattggag
     7081 tcagatgttg acggagataa atcagataac ctacctgtag aaatcaaagt cctagctcag
     7141 cgagtagaag tattttcaaa accgaaagag gattagtata tagagaaagc cttttttaag
     7201 gctttttgta tactttaaaa gatagttcct ttaacaacgg acattccttg caaatagttt
     7261 acaaaaatag tatactggat tcattgagtt tgaaaacgtt tgcgtaaaat ttgaatgaat
     7321 actttaggag acaaattgat ggaattgagt gctatttacc ataggcctga gtcggagtat
     7381 gcctatcttt ataaggataa gaaactccat attcgaattc gaactaagaa aggggacatt
     7441 gaaagcatca acttgcacta tggggaccct tttatcttta tggaggagtt ttatcaggat
     7501 acaaaagaaa tggtcaagat aacttctggt accttatttg accattggca ggttgaagtg
     7561 tcagttgact ttgcacgtat ccagtatctc tttgagctca gagatacaga aggtcaaaat
     7621 attttgtatg gcgataaagg gtgtgtggaa aattctctag aaaatcttca tgcaatcggg
     7681 aatggattta agttgcctta tcttcatgag attgatgcct gcaaggttcc tgactgggtt
     7741 tcaaatacgg tatggtatca gatatttcct gaaaggtttg ccaatggcaa tgctctatta
     7801 aacccagaag ggactttaga ctgggattca tctgtcacac ctaagagcga tgatttcttt
     7861 ggtggtgatt tacaggggat tattgatcat atggattact tgcaagactt gggtattact
     7921 ggactatatc tttgtcccat ctttgaatct acaagcaatc acaagtacaa tacgacagat
     7981 tactttgaaa ttgaccgtca ttttggagac aaggagacct ttcgggaact ggtggatcaa
     8041 gcgcatcatc gtggcatgaa agtcatgctg gatgcggtat ttaatcatat tggttcgcaa
     8101 tctcttcaat ggaaaaatgt cgtcaaaaat ggtgaacagt ctgcttataa ggattggttc
     8161 catattcaac aattcccagt gacaactgaa aagctagtta ataagagaga cttaccctat
     8221 catgtttttg gtttcgagga ctatatgcct aagctaaata cagccaatcc agaggtcaag
     8281 aattatcttt taaaggttgc gacttattgg attgaagagt ttaatatcga tgcttggcgt
     8341 ttggatgtgg ctaatgagat tgaccatcag ttctggaagg attttcgtaa ggcagtttta
     8401 gctaaaaatc ctgatcttta tatcctagga gaagtctggc atacatctca gccttggcta
     8461 aatggagatg agttccatgc cgtcatgaat tatcctttat ctgatagtat caaggactat
     8521 ttcttacgag gaattaagaa gacagaccag ttcatcgatg aaatcaatgg agagtttatg
     8581 tattacaagc agcagatttc agaggtcatg tttaatctct tggattcaca tgatacagag
     8641 cgaatcctgt ggacggccaa tgaagatgtt caactggtta aatcagcctt agcctttctc
     8701 tttttacaaa aaggaacacc gtgcatttat tacggaaccg agctagcctt gactggagga
     8761 ccagatccag attgtcgtcg ttgtatgcct tgggaacgtg tatcaagtga caatgatatg
     8821 ctgaacttta tgaagaggct gattaaaatt cggaaatacg cgtcagtaat catttcgcat
     8881 ggcaagtata gccttcaaga aatcaaatct gatctagtag ctctggaatg gaaatacgaa
     8941 ggacggatcc tcaaagcaat attcaaccaa tcaacagaag attatctttt agagaaagaa
     9001 gcagtagcac tagcaagcaa ttgccaagaa ttggagaatc agcttgtcat ctctccagat
     9061 ggatttgtga ttttctaaaa actagttgat gaagattatg gtacatttca tatcttatat
     9121 agtataataa ggctagttac taaacttgta aaggagaact taaatgaatt gtagaggaca
     9181 tgaaacaaga caaagaattg ttagagattt tgaagtttag cctaaagcac atattaagct
     9241 gttagcaaat caacaaaaac atagtgatgc aggagcaact attgaagatg aatattatgt
     9301 atttatcgct gagagtaaaa ttgatggcaa gaaggaagtt attcagtgtt gcatgggtgc
     9361 ggcaagggat tttttagaac taattaatca caaagggcta cctcttttta atccgcttgt
     9421 aggtgattct catgtaaata atagacaaga atatgacaat acagggagtg gaaatttaca
     9481 acctgaaaag tggaatgaaa ctgcaaagca gctttataat gttataatgt ggttgattat
     9541 tttatggaat gctaagccgg atacaccttt atttaatttt aaagacgaag taattaagta
     9601 taaaacatat gagccttttg aaagcagtat aaaaagagta aatactacta taaagaatgg
     9661 tagtaaaggg aaaactctga ctgagatgat taatggctac agagcggata acgatattag
     9721 agatgaaatt tgtaacttta atattctgaa aaataaaatt cgtgatatga aagaccaaca
     9781 aggaaataca atggaatctt acttt
//
LOCUS       DAVKMO010000061         8599 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVKMO010000061 DAVKMO010000000
VERSION     DAVKMO010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8599
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.061"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     misc_feature    78..213
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            252..752
                     /locus_tag="VW361_001801"
     CDS             252..752
                     /locus_tag="VW361_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU9744798.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            828..1196
                     /gene="rplL"
                     /locus_tag="VW361_001802"
     CDS             828..1196
                     /gene="rplL"
                     /locus_tag="VW361_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU9744799.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            1383..1553
                     /locus_tag="VW361_001803"
     CDS             1383..1553
                     /locus_tag="VW361_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744800.1"
                     /translation="MQKEGQSSRQFMKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            1553..1801
                     /locus_tag="VW361_001804"
                     /pseudo
     CDS             1553..1801
                     /locus_tag="VW361_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            1815..2138
                     /locus_tag="VW361_001805"
     CDS             1815..2138
                     /locus_tag="VW361_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744801.1"
                     /translation="MTFLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDH
                     QNLVFVLYGQGYRAEGKEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLW
                     EVSYD"
     gene            2131..2511
                     /locus_tag="VW361_001806"
     CDS             2131..2511
                     /locus_tag="VW361_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744802.1"
                     /translation="MIDLYLSKNSRRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLKLTDFIEMILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            2524..2757
                     /locus_tag="VW361_001807"
     CDS             2524..2757
                     /locus_tag="VW361_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU9744803.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            2760..3347
                     /locus_tag="VW361_001808"
     CDS             2760..3347
                     /locus_tag="VW361_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9744804.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYCASLIS
                     FLWMYAQRKQAHKVNMKSRIKWIGIGLASLLIISLCFSLIHAQESTNQANLIGLQYQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            3549..3686
                     /locus_tag="VW361_001809"
                     /pseudo
     CDS             3549..3686
                     /locus_tag="VW361_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
     gene            4480..4767
                     /locus_tag="VW361_001810"
     CDS             4480..4767
                     /locus_tag="VW361_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744805.1"
                     /translation="MKVVNLYDLKQMGNKGGCTIQLIHHFPFGMGLGHLKKDYIEFKR
                     VGIFDGKAVEVTLREPYSRDILQVVKSIKQRQKLIAYRYKEGKLLFVKKEV"
     gene            4925..5221
                     /locus_tag="VW361_001811"
     CDS             4925..5221
                     /locus_tag="VW361_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000941983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744806.1"
                     /translation="MLQSPYAIDTINLKKDFLEKPIDIEKFKAFLEKEEIPLAIAWQG
                     DSLHFYTKDRSILDNHLDHLLEKMVNDPEKLSDFSMDKSLDDTIDEAKSQITFK"
     gene            complement(5455..6501)
                     /locus_tag="VW361_001812"
                     /pseudo
     CDS             complement(5455..6501)
                     /locus_tag="VW361_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            6757..7566
                     /locus_tag="VW361_001813"
                     /pseudo
     CDS             6757..7566
                     /locus_tag="VW361_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            7583..8161
                     /locus_tag="VW361_001814"
                     /pseudo
     CDS             7583..8161
                     /locus_tag="VW361_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            8174..8344
                     /locus_tag="VW361_001815"
     CDS             8174..8344
                     /locus_tag="VW361_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744807.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT         2810 a         1350 c         1712 g         2727 t
ORIGIN      
        1 aaaagaaaaa tcacgaaaaa ttttaaaaaa agtttgcaaa aatcttgcat tctttttttg
       61 actatgctat acttatatac ggtttaaaaa aactgcctaa gacagtaggg gagctcgact
      121 cataaatatc ctaccgagga caaaacgtat catgtaaaaa gaagcgtatt gtactttcgt
      181 gtctaggttt gggcgcgttt ttctttttga aaaattcccc aagcaaaata attacggagg
      241 tgaacacact aatgagtgaa gcaattattg ctaaaaaagc ggaactagtt gacgtagtag
      301 ctgaaaaaat gaaagctgct gcatctatcg tcgttgtaga cgctcgtggt ttgacagttg
      361 agcaagatac agttcttcgt cgtgagcttc gtggaagcga agttgagtat aaagttatta
      421 aaaactcaat cttgcgtcgt gcagctgaaa aagctggtct tgaagatctt gcatctgtat
      481 ttgttggacc atctgcagta gcattttcta atgaagatgt tatcgcacca gcgaaaatct
      541 tgaacgactt ttctaaaaac gctgaagcac ttgaaattaa aggtggtgca atcgaaggcg
      601 ctgtcgcatc taaagaagag attcttgcac ttgcaactct tccaaaccgc gaaggacttc
      661 tttctatgct cctttctgta cttcaagcgc cagtgcgcaa cgttgctctt gcagtcaaag
      721 cggttgcaga aagcaaagaa gacgcggctt aatcttaagc tacacagcgt agcctagcta
      781 cgaaaaaaac tattataaaa tttaaaactt atttggagga aataacaatg gcattgaaca
      841 ttgaaaacat tattgctgaa attaaagaag cttcaatcct tgaattgaac gaccttgtaa
      901 aagctatcga agaagaattt ggtgtaactg cagctgctcc tgtagctgtt gctgcagctg
      961 atgcagctga tgctggtgct gctaaagatt cattcgacgt tgaattgaca tctgcaggcg
     1021 acaaaaaagt tggcgttatc aaagttgtac gtgaaatcac tggtcttggt cttaaagaag
     1081 ctaaagaact tgttgacggt gcaccagcac ttgttaaaga aggcgttgca actgcagaag
     1141 ctgaagaaat caaagctaaa ttggaagaag ctggagcttc agttactctt aaataataga
     1201 gtatcgcaat ttgattgcgg aatccctatt taccagtctt tgagagcgat aagcgattga
     1261 tagaaactga taaattgatt tggtttcctg ccaaaaattc tttggcagga tttttgtttt
     1321 aataaacttt cgggggtaga cactagattg tctacccctt tttttgtgtt tcggaggtaa
     1381 ttatgcaaaa ggaaggacag tcatcacgtc aattcatgaa gagtcatctc atgactatca
     1441 tgggagttga tattgtaaaa gcaactcagt tagttgatga aatggaacaa gtaggtttaa
     1501 tccgatttga tgaatttgga aatgttggaa ttttagtctt ggagggacaa taatgaagcg
     1561 tattaccgct aatcaatatc agacatcaga gcgttattat aagctcccca aacttttatt
     1621 tgagagtgaa cggtataaga atatgaaacc ggaggttaag gtggtttact cagttttaaa
     1681 agatcggttg gagttgtctt tgagcaaagg ttggattgat gaggatggga ctatttattt
     1741 gatttattcc aattcaaatt tgatggcact tttaggctgt tcaaagtcaa aattactctc
     1801 catgtgagtt tgaagtgaca tttttagatg attaccataa aaaacataac tacccactat
     1861 tttacgaatc ctatcttcaa aacgttatgg aattccttga aagtcaagac ataaagaatg
     1921 gggttgatgc ctttgtagat gatcatcaaa atctcgtttt tgttttatat ggacaaggct
     1981 atcgagccga gggaaaagag ggaatactta caacccaagt aactgtaaaa gcttatgatg
     2041 aagacaagaa accgattaac ttcgcaaatt tattagattc cttaatcgtg tcagaatatc
     2101 aaatggaacc gaatctttgg gaggtctcct atgattgatc tctatctaag taaaaatagc
     2161 cgaagaaatc aacttctttt agacttcttc caaaactatg gcatcgaggt atcttgtcat
     2221 tcagtttctg aaatgacaaa ggacaaatta attgagatga tgagctattc ttcagattgt
     2281 tttgagtttt tatctccaaa tttattacgt tttaagaatc gagataacct aaaattaaca
     2341 gatttcatcg aaatgatatt aaaaaatcct gaactaacca tcagacttcc tcttgcggtt
     2401 tcaaataagc gagtttatcc aagtctgaat ttggaagagg ctagagctct attgccaaga
     2461 gatacgaaac aattgattta catggcgcaa acacattatt tatctaacta aaggagaagc
     2521 aatatggctg aacgattttg ggagaacttg tccattattt tggctgaaag aaatatcagc
     2581 tggattgagc taaccagaaa aatgtttgcg ggagagtttc actatccaag tgaattgaat
     2641 cgtttgtatc aaaagattcg tcactacaag atggaacaac gaatgcctca aagtccatgg
     2701 gtagaaagga ttgtgcaggt attagattta gattatgaag atttatttcg gaggtaacta
     2761 tgaaaagaat aattccagtt tatatattcc aacaagtaaa tgtcctattg gtatctctat
     2821 acttactgaa atttctttgt atcggtgagt taactatact acagattcta tattgtgcgt
     2881 cactcatttc ttttttatgg atgtatgccc aacgtaaaca agcgcataag gtcaatatga
     2941 aatcaaggat aaaatggatt ggtattggat tagccagtct actgattata agtctatgtt
     3001 ttagtctaat ccatgcgcaa gaaagcacga atcaagcaaa cttaattggg cttcaatatc
     3061 aagttccttg gttttcattt ttattgttct taatcaatgc gagtatggtt gaagaatttc
     3121 tgtatagaga aattttatgg aacttggtta gaaaattaga tattcgagtt gctttgacaa
     3181 gtgttttatt tgccttagca catcatccag gaaccattat agcttggtgt ttgtatgtat
     3241 cgctggggat gtttttaggg cttgtacgct acaaattgga cttatggggc agtatggggc
     3301 tacatttggt gtggaaccta ctagtttata gtttgctgct tttttaaaat aggtaacctg
     3361 atttttaggt aacttctaaa actaacttcc agttttggga gagagatgga agttactttg
     3421 aaaagttacg gaaacattat tttctatgtg acaacattgt atcattgctt gcattttact
     3481 gctggagaga gtataatgaa tgtggataaa gcacttaatc ccaaaaattt aaataggagg
     3541 agttagctat ggcagaagaa gtattaaatc tttaattagt atctgttcaa gttgacgaaa
     3601 cagatgaagt tgatggaatg cgatttagta cattcagtac aaaccgttgc ggtaactgga
     3661 gtgcttttag ttgggaaaat tgttaattca tttaaattgt aaactttaga gattctctgg
     3721 agttatggat ctcgttccaa tatgtgcacg ttggaatgtt agtgcttata tggggggaac
     3781 agaatcctct cttgattgaa gacaagctag tcattaggct agtttgtctt tttgtcaact
     3841 gtagtgggtt gatataatag tattagtgag tgggataaaa gtttcattta gtttattcag
     3901 tacaaattta acgggtcaag atttatatac tggtggtgtt tttggggctg agagaagtat
     3961 cttgatttta tgtgtggttt ttatacttac agttgttctg ctccaaagag cttgtagaga
     4021 agaattagct cataaaggag attgattatt ttgatatcaa aaaaatgcac aggataacct
     4081 gatgcatttt tttagcgaca atgcttgcta cttccttctg tcgaatttag acaattttaa
     4141 ataaaagaat gaaatattcc ctactgtatt tttagacgaa gaacgttagt taataatact
     4201 caaatttatt tcaaactctt tgattagtat gaatttagct ctacagaaaa ataaaaaatg
     4261 tgataaaaat ttcaactact cttatctata ataaagctac ctgttctttg aaaattgaat
     4321 ccactccgtc ttgattagcg tgcctgtgta agtagggact gagagtattt ccctgtgaag
     4381 ggcaactggc acaagacgtg tgtgagaatt ttctaacaga cacggagttt atcgtttcca
     4441 gactcaaacg atgcgacaaa ctagataaag gagttaatca tgaaggtagt aaacttgtat
     4501 gatttgaaac aaatgggaaa taaaggtggt tgtaccatcc aattgattca tcactttcct
     4561 tttggtatgg gcttaggaca tctcaaaaag gactacattg aatttaaacg tgttggtatc
     4621 tttgatggga aagcagtaga agttactctt cgagaacctt attcgagaga tatactgcag
     4681 gttgtcaagt cgattaagca acgtcagaaa ttgatagctt atcgttataa agaaggaaag
     4741 ctgctatttg ttaagaagga ggtctgagat gtcctctgaa caacaggaac gaatggcagt
     4801 tcaatatgct gagcgtagtc ttttatttac tgtaaaaggt cttttaaaga tactagaatg
     4861 gtctagatgt caggctttag aacaggattc cgcctataag ataggggtgt agaaattaga
     4921 agaattgcta caatctccct atgcgattga tacgattaat ctgaaaaaag attttttaga
     4981 aaaaccaatt gatatagaga aatttaaagc ttttttagaa aaagaagaga ttcctttagc
     5041 catcgcttgg caaggggatt ctctgcattt ctacacgaaa gaccgttcga ttctagacaa
     5101 tcatttagac catctgttag aaaaaatggt gaatgatcct gagaaattat ctgatttttc
     5161 catggataag tcattagacg atacaattga tgaggctaaa tcccaaatta cctttaaata
     5221 atagagtatc gcaatttgat tgcggaactc ttgtttaatg agagttgaga taatataaag
     5281 gcgataataa ttgggagaat aattatattc cccgccaaac cccactaagt ttttatcttg
     5341 gtggggtttc ttggtacgac ttacccttat taaaattatt atgtagtttt tttgaattta
     5401 gcatcatcaa gattctgatt gttttgatat tgacttttca tttatttcta atactcatct
     5461 gttttcaaaa agcattctag tccatctccg attaacgatg gactttatca cctccttctc
     5521 cagtccttgt atgacatctt gaagttgatt catgacatct tccaaagttc gaaaggcctt
     5581 attcttaaat ccacgtttac gaatctcttt ccacacttgt tcaatgggtt catctctggt
     5641 gtgtatggag gaataaaggt aaaaccaata ttagtcggaa tctttaaggt acttgattta
     5701 tgccatatag cattgtccat aacgagtaaa agataatcat ctggataagc ttgtgaaagc
     5761 tcttctaaaa aggagttcat ccactcagta ttacatccac cagctattaa gaaaaatgat
     5821 tcgcctgtat gggcatcaac agctccataa caatagtgaa attctcgtat atagtgacta
     5881 tggacatgtg gacctactcc tattggagac caacaagatc ccagtttact gattctaccg
     5941 aaaccagcct catcttggta catcaagcga accttatgaa aacgtctact ggttttaaat
     6001 cgctttcttg tcttcttgaa ttgagatttt atttttagac gcgacaatgg tttgagcgtc
     6061 tgctttctta ggatgttctg gacgtggcat aatatttcgc cagccatggc gcttcaacag
     6121 ttgatagaag gcatcacgtg tgtaggaacg acctaactcc tttttataag cctgaaataa
     6181 ggcatcaatt gtaacaaatt ctcctgcctc tgtagccttc aaatggcggg caagaaagac
     6241 tttctcttcc tcaactgtca tatatgcatg gttacgacca ccacgtgttt cttgaaggag
     6301 agagtcgagt ccgaactcct catatttttt tacattttgc taaatcgttg tttaattaca
     6361 gtctaaaagc tctataatct ctttataaga tttgcccatc agacgaaata gaacgatttg
     6421 aaggcgttta tgatatttag ctgtacgaga gtcttttaaa agtgttttga tggtttggat
     6481 ttcttcttta gttgatttca tatcactatt gtataatgct ttttgatttt agtctagtat
     6541 aaatagcgag aaatatctat cctatcttct agaatgtctt ccaaacgagg aaactctcgt
     6601 aaacaaagag gttttagagg cctatttacc gtggactaaa gttgtacaag aaaagtgcaa
     6661 ataagaaatc tccagattag gaactatccg tgagttctct agtctggaga tttttcaata
     6721 gacttcctgc gaaacaaaat atggtataat agttctatga atgatgaagc aagtaaacaa
     6781 ctaaccgatg cacgatttaa gcgtcttgtt ggtgttcaac gcacgacttt tgaagagatg
     6841 ttagctgtat taaaaacagc ttatcaactt aaacacgcaa aaggtggacg aaaacctaaa
     6901 ttaagcctag aagactttct tatggccact cttcaatatg tgcgagaata ccgcacttat
     6961 gaagaaattg cggctgattt tggtatccac gaaagcaact tactccgtcg gagccaatgg
     7021 gttgaagtaa ctcttgttca aaggtggtgt tacgatttca agaactcctc tcagttctga
     7081 agacacggta atgattgatg cgacggaagt aaaaatcaat cgccctaaaa aaaaaaacaa
     7141 ttagcgaatg attctggtaa aaagaaattt tacgctatga aggctcaagc gattgtcaca
     7201 agtcaaggaa gaattatttc tttggatatc actgtgaact attgtcatga tatgaagttg
     7261 ttcaaaatga gtcgcggaaa tatcggacaa gctggtaaaa tcttggctga cagtaattat
     7321 caagggctca tgaagatata tcctcaagca caaactccac gtaaatccag caaactcaag
     7381 ccgctaatag ctgaagataa agcctataac catgcactat ctaaggatag aagcaaggtt
     7441 gagaacatcc ttgccaaagt aaaaacgttt aaaatgtttt caacaaccta tcgaaatcat
     7501 cgtaaacgct ttggattacg aatgaatttg agtgctggta ttatcaatca tgaactagga
     7561 ttctagtttt gcaggaagtc tattatcaaa aataccatca ggattatata agattgatac
     7621 aggaaaagtt ttatttgatg gtgtaaatat taatcaaata gataaaaaaa tattaagtca
     7681 aaatttagga gtagttccac aggattcgtt tttattgaac agaagtattc ttgataacat
     7741 aactttaaag cacgaagtta cttcacaaaa gatagaggaa gtttgtaaag cagttcaaat
     7801 ctatgatgaa atcatggcta tgccgatgaa atttaatact atcatctcag agatgggttc
     7861 aaatatttca ggtggtcaaa gacaacggat agcactggca cgtgcattaa taaataatcc
     7921 tagtattgta attttagatg aagcaactag tgctttagac actattaatg aggaaagaat
     7981 aacaaagtat ataaaaagtc agggctgtac tcaaataatt gtagctcata gattgtcaac
     8041 gattaaggat gcggatatta ttgttgtaat gaaaggtggt aagattgttg agtcaggaaa
     8101 tcataagtac ttaatggatc ttggtggaga gtactacagc ttatatacaa aaaggaaatg
     8161 aggtgtaaag aaaatgaaga aagaaaatga atatgtaatt ttaacaacag cctcactagg
     8221 ggtgatgatt ggaatagtgt ttgcaatttt tttagatttt ccagttgaat atggtatttc
     8281 tttaggattg ttgaatggaa tagtattggg ttcgctgatt gtttacaaaa acaataagaa
     8341 ttaagcataa ttttttgctg taaactaagg agtagagatg gctatagttg aaattataaa
     8401 tctaacaaaa agctttaaag atattgaagt tattcataac acttaaataa tagagcaact
     8461 acagtagtag cttaaaaaca tgattaaatc gctattctta ggagtagcgt tttttctttt
     8521 tgtttaatac tctttgaaaa tctcttcaaa ccacgtcagc tttgccttgc cgtactcaag
     8581 tacagcctgc gactcgctt
//
LOCUS       DAVKMO010000062         8561 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVKMO010000062 DAVKMO010000000
VERSION     DAVKMO010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8561)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8561)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8561
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.062"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            80..395
                     /locus_tag="VW361_001816"
                     /pseudo
     CDS             80..395
                     /locus_tag="VW361_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
     gene            610..726
                     /locus_tag="VW361_001817"
     CDS             610..726
                     /locus_tag="VW361_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU9744808.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            719..970
                     /locus_tag="VW361_001818"
     CDS             719..970
                     /locus_tag="VW361_001818"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744809.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGLSVSEFEPFCVEKSPI"
     gene            1014..1292
                     /locus_tag="VW361_001819"
                     /pseudo
     CDS             1014..1292
                     /locus_tag="VW361_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1429..2397)
                     /locus_tag="VW361_001820"
     CDS             complement(1429..2397)
                     /locus_tag="VW361_001820"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9744810.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(2542..3084)
                     /locus_tag="VW361_001821"
     CDS             complement(2542..3084)
                     /locus_tag="VW361_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001839529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU9744811.1"
                     /translation="MDQLLGVLFPDSTFLNAFESAIVAPLVEEPLKLLPLVFVLALIP
                     VRKLKSLFLLGIASGLGFQMIEDIGYIRTDLPEGFDFTISRILERIISGIASHWTFSG
                     LAVVGVYLLYRAYKGQKVGKKQGLIFLGLALGTHFLFNSPFVELETELPLAIPVVTAI
                     ALYGFYHAYCFVEKHNELMT"
     gene            complement(3088..3372)
                     /locus_tag="VW361_001822"
     CDS             complement(3088..3372)
                     /locus_tag="VW361_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744812.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFLALFYM
                     IPALYFLFHIGKKWELPKKVLILSLLGAICSFTSLLLFGIYNHRRKSSKV"
     gene            complement(3397..3894)
                     /locus_tag="VW361_001823"
     CDS             complement(3397..3894)
                     /locus_tag="VW361_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU9744813.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(3967..5328)
                     /gene="radA"
                     /locus_tag="VW361_001824"
     CDS             complement(3967..5328)
                     /gene="radA"
                     /locus_tag="VW361_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU9744814.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(5342..5857)
                     /locus_tag="VW361_001825"
     CDS             complement(5342..5857)
                     /locus_tag="VW361_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9744815.1"
                     /translation="MKIIFVRHGEPDYRELEERFYIGFGIDLAPLSEMGRQQVQKLSK
                     TPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(5859..6302)
                     /locus_tag="VW361_001826"
     CDS             complement(5859..6302)
                     /locus_tag="VW361_001826"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU9744816.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(6362..6455)
                     /gene="ffs"
                     /locus_tag="VW361_001827"
     ncRNA           complement(6362..6455)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VW361_001827"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(6488..6955)
                     /locus_tag="VW361_001828"
     CDS             complement(6488..6955)
                     /locus_tag="VW361_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU9744817.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(7156..8442)
                     /locus_tag="VW361_001829"
     CDS             complement(7156..8442)
                     /locus_tag="VW361_001829"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU9744818.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
BASE COUNT         2681 a         2073 c         1471 g         2336 t
ORIGIN      
        1 ttcacatctt atttcaactc actatagaag gaggaatagg aggattctca gacatccggg
       61 catcagccca actaatgatt tgattgctaa gaaaatattc agcaatccag aaatcacttg
      121 tcaatttatt cgcgatatgc tggacttgcc agcaaaaaat gtgaccattt tggagggaag
      181 cgatattcac gtattacttc tccatgcctt actcagtgca ggatttttat accagtatag
      241 acgtcttggc ggagttggat aacggtactc aagtaattat tgagattcaa gtccatcatc
      301 agaatttttt catcaatcac ttgtggactt acctgtgcag tcaggttaat caaaatcttg
      361 aaaaaattcg tcagcgagaa ggtgatactc actagagcta caaacacatc gctcctgttt
      421 acgccattgc tatcgtggat agtaattatt tctcagatga cctggctttt catagcttta
      481 gtatgcgcga agacacaaca ggtgaggtat tggcgattac caacaatgga caggaaaacc
      541 atctggttaa gatggcattc ttggaattaa aaaatacaga gaaaccagca aggacgaggt
      601 tcgcaagcca tggttggagt ttttcggcaa caagcccttt acccagcaac cgcaacgagc
      661 cattacccaa gcaaatcaac tgctggacta caagagctgg tccgaggagg acaggaaaat
      721 gtttagtcaa ctacatatgc gagaagaaca agtcttgtta gcacaggact atgccttgga
      781 aactgctagg gctgaaggcc ttgaacaagg actagagcgt gggaaagttg aaggaagggc
      841 agaaaggaaa ctttttgcct tcctagacat agtacgccaa ggtcttctga cttctgaggt
      901 tgccagccag caattaggtc tgtcagtatc tgaatttgag ccattttgtg tagaaaaaag
      961 tcccatataa cctataatga aaagcgacaa aacaactcat tagaaagaat catatggaac
     1021 aattacattt tatcacaaaa ttactagaca ttaaagaccc taatgtccag attttaaaca
     1081 tcatcaataa ggatacacac aaggaaatca tcgccaaact ggactacgac gccccatctt
     1141 gccctgagtg cggaaaccaa ttgaagaaat atgactttca aaaaccttct aaaattcctt
     1201 atcttgaaac gactggtata cctactagaa ttctccttag aaagcgtcga ttcaagtgct
     1261 atcactgttc aaaaatgatg gtcgctgaaa cttatgatga cgtacagtca tatttcttct
     1321 ctttttatta tatcacagtt ttaaatctag ctttactaga ttcaccgcta ctatctattt
     1381 attcggaaaa aagacgaaaa aacctgagaa tcatctcagg cttggtcatt aaattttttt
     1441 ctcaatatcg aaaagtggag aaagtggtcg tttttcatga atacgtacga tagcatcccc
     1501 taggagatga gcgattgaaa tctgctcaat cttatcaatc aaacgctctt ctggcagata
     1561 gatggtatcc aaaacaacca atttcttaat agctgatttt tggatattgt ccgtagcagg
     1621 accagaaaga actgggtgcg tacagcttgc atagacttca acagcaccag cttccgcaag
     1681 agcatctgcc gcatgacaaa tcgttccagc ggtatcaatc atatcatcaa tcaagataca
     1741 agtcttgcct tcaaccttac cgatgatgtt cataacttca ctagtattca tcttatcaac
     1801 gctacgacgt ttatcaataa tagcgataga tgttttcaaa aattctgcca acttacgagc
     1861 acgagtcacc cctccatggt ccgggctgac aaccacatag tcagaaccaa ccataccacg
     1921 acgctcaaaa taatctgcaa tcagaggagc acccatcaaa tgatccacag gaatatcaaa
     1981 gaatccttga atttgcgcag catgcaagtc gatggtcaat aaacgatcca ctccagctac
     2041 ttcaagcata tttgcgacaa gttttgaagt gattggctca cgcgctctcg cctttctatc
     2101 ctgacgtgca tacccatagt aaggcatgac aacattgaca gattctgcac tcgcacgctt
     2161 caaagcatct accataatca aaatttcaag cagattgtca tttacaggcg aactagttga
     2221 ttgtaagata aagacgtgtt tcccacggat tgattcttca atgttgacct gaatctctcc
     2281 atctgaaaat tggcgaacac ttgatttccc caactctatc ccaatctcct gcgccacacg
     2341 ttctgccaat tctttattag aagaaagggc aaacagcttt aaatcagaaa aagacatgat
     2401 ttcctccggt atatatgtat aacttgtgtt tttcacaaga ttttccatct accattgtag
     2461 cgctttttgc actatttttc aatcaaaaat aaaagaaggg caccatattt gtacccttgc
     2521 atcattcttt tgaaaaatat tctaggtcat caactcattg tgtttctcaa caaagcaata
     2581 agcatgataa aaaccataga gagcaatagc cgtaaccact ggaatcgcta aaggcaactc
     2641 tgtttccaac tccacaaaag gagagttaaa caagaagtga gttcccaagg ctaaacctag
     2701 aaaaataagg ccctgtttct tgccaacctt ctgtccttta taggctctgt aaagcaagta
     2761 aacacctact acagctagac ctgaaaaagt ccagtgagag gcaattcctg agatgatacg
     2821 ctctaaaatt cgcgaaatag taaagtcaaa gccctctggc aaatccgtac gaatataacc
     2881 aatatcctca atcatttgga atcccaaacc ggaagcaatt ccaagtaaaa acaaagattt
     2941 taattttcgc acaggaatca aagccaaaac aaaaacaagt ggcaataatt tcaagggttc
     3001 ttctaccaaa ggagccacaa tagcactttc aaaggcattt aaaaatgtac tatctgggaa
     3061 aagaaccccc agtaactggt cgatttttta taccttagat gactttcgtc tgtgattata
     3121 gattccaaat agtaagagag aagtaaagga acagattgct cccaataaag acagaatcaa
     3181 aaccttcttt ggcaattccc attttttccc aatatggaag agaaaataaa gagccggaat
     3241 catgtaaaag agagctagaa agatagaaac tcccattagt ccatattccg cacctgacct
     3301 cgaaccgtcc gtatagtaga tggtttcata ctgtaaacca atacatagca ataaaatact
     3361 gcttttcttc atacactttc tttctaaatg aagtatttat aattctacga ctgtcatact
     3421 tcctgtatca acattgtaaa tagcaccaga gataatgaca tcgtctggta ttaggggaga
     3481 ctcgataagc agttgcatat cctcgcgtac actctcttct atatcttgga agggcaagaa
     3541 gtcctggtct gacacatcta cacctaattc ctcttttaaa tactcctgaa aaggttcatt
     3601 ttcaaaggtc tgagcaccac agtctgtatg gtgcaatacc acaatctctc ttgtccccat
     3661 ttgttgctgg gaaataacta gcgaacgaat catgtcttca gtcactcgac cacctgcatt
     3721 ccgcaagata tgagcatccc caagtgccaa gcccagagct tgcgcaacgt gcagacgaga
     3781 gtccatacag gtcacaatag ctactcttgt tttgggttta agtggcagat ttaactgccc
     3841 atgtagggca acataagcct gattagcttg cataaactgt tcaaaatacg acacgattcc
     3901 ctccttgaaa atttgatagt caaatatttc tcctatctta tcatttttaa gagaatttgt
     3961 cacggattat gcaaagacct ttttcaaaac ttcctgaatc gttgtcacgc caatgacctg
     4021 aatttcctta ggcagagtga ttcctgtcaa ggaattctta ggtacataaa tcttagtaaa
     4081 gcccagttta gcagcttcgt tgatgcgttg ctcaatacga ttcacgcgcc gaatctctcc
     4141 tgtcaagccc agttctccga caaaacattc ctgaggatta gttggcttgt ctttgtagct
     4201 cgaagcaata gcaactgcaa cagccaagtc aatggcaggt tcatccaatt taacaccacc
     4261 agcagatttg agataggcat cctgattttg caagagaagc cctgcccgtt tttccaaaac
     4321 agccataatc aagctagcac ggttaaaatc aagtcctgtc gtagtacgct tggcatttcc
     4381 aaacatggtc ggtgttacca aagcctgaac ctccgccaaa atcggacgcg tcccttccat
     4441 ggttacaacg atggaggaac cagtcgcccc atccaaacgc tcttctagga aaacttgact
     4501 cggattgagt acctcaacca agccgcccga ctgcatctca aaaatcccaa tctcattagt
     4561 ggaaccaaaa cgatttttga ccgctctcaa aatacgaaag gtgtggtgac gctccccttc
     4621 aaagtaaagc accgtatcca ccatatgctc caacatacga ggcccagcca aggttccttc
     4681 tttggtcaca tgacctacga taaagatggc aatgttattg gtcttggcca actgcatgag
     4741 ttcagcggtc acttcacgca cctgagaaac agacccctgc acccctgaaa tctcaggaga
     4801 catgatggtc tggatggaat caataatgag aaagtctggc tggatacgct ccacttctgc
     4861 acgaacactc tgcatattgg tctctgcata gagataaaac tcactatcaa tatcacctaa
     4921 gcgctctgca cgtagtttaa tctgctgggc agactcctcc ccactgacat agagaactgt
     4981 ccccacttgg gacaactggg ttgagacttg taggagaaga gttgatttcc caatcccagg
     5041 atccccaccg atgaggacga gacttcctgg tacaactccg cctccaagca cacggttgaa
     5101 ttcctccatc tccgtcttgg ttcgattgac attgatggaa gtcacctcag ctagtttcat
     5161 gggcttggtt ttctcacctg tcaaggacac acgcgcattc ttgacctcgg caacctcaac
     5221 ctcttccaca aaagaagacc aagacccaca gttggggcaa cgtcccagat atttagggga
     5281 attataccca caattttgac atacaaatgt cgcttttttc tttgcgatga caaacctctt
     5341 tctatatctc taactcacac tcaatcactt ggcaaaaatc aatcttctca tttggcacaa
     5401 actggcgcat gagcattcga tgagcaacaa ctaccacagt ctgatgttct cgatacttag
     5461 acatacattc tagaaaccga gacttcattt ccgtagctgt ctcatattga ataggactat
     5521 taggaagcaa ctcccccttg ttttctaaaa acagtcttct agctgtttca aagttttcta
     5581 ttcctgtttt atagacctgc cattcatgta ataaaggctc tactcttaaa ggaagacccg
     5641 tagcacagac cacatacgaa gccgtttcta aagctcttgt gactgcagaa gatacgatta
     5701 tttcagctga cgagagtaaa ggagttttgc tcaatttctg gacttgctgc cgtcccatct
     5761 cagacaaggg tgccaaatct atcccaaatc ctatataaaa acgctcctct aactcacggt
     5821 aatctggctc cccatgacgt acaaagataa tcttcattct agtgccctgt cgatccaaat
     5881 ccaccagttc gaacgccatc agccgcatct ccatctgcaa ttaagaaagt agcaaaaaca
     5941 gcctggacaa tacgctcccc aacttcaaga acaacctctt ggtctgtgat attcttcatc
     6001 tgcgcaaaaa tatgcccttc atttccagga tttccataat aatccccatc aatgacccca
     6061 actgagttaa ttaaaaccaa gcccttctta cgaggatttg aagaacgatc atagaggtag
     6121 agaacctcag tcggctgcat ataagcctta acccctgtcg gaaccaagac aatctctcct
     6181 ggcgcaacaa ctgtacgcac agcaaccttt aagtcgtaac cagccgcatg cgctgtctca
     6241 cgcttgggca ataaattttc atctgtaaaa ctcgaaacca attcaaaacc acgaattttc
     6301 ataattttct cttttctatt atcatttatt ctagattatt ctatcttatt tattcggaaa
     6361 aagcacgaaa aaagagcaca caattcaaat cgcttagggc tgctggattc ctcccctgac
     6421 ccgcttcacg cagaactgtt gctccactat ttattatatc acattcctat tcattttaaa
     6481 agcaaaatta ttttttccgt ctatttctaa aaaaatcctg catgatagct gcgcattcat
     6541 cttccaaaat tcctatttca acctccacac gatgattgag acgctcatct gtcaagatat
     6601 cgtacaaact cccagcagcg ccaaatttct ggtttttagc cccatagacc acatttggaa
     6661 tgcgggcaag cccaatcgcc ccactacaca tgacacaagg ttcaatggtc acaaaaagtg
     6721 tgcaatccag caagcgccag ctctcctcac tcaagttcgc atcctctata gccataattt
     6781 ccgcatgcat aaccgctcgc tgtaattcct cacgcgcatt atgcccacga ccaatgattt
     6841 ccccatcttt gacaatcaca caaccaattg gaatttcatc gtgttcaaga gcaatctcag
     6901 cctctctcaa agcctccctc ataaagactt ctttttcttc aagcgtataa tacatctctt
     6961 ttctcttttc ctacttatcg attttattat tatatcatga atcccaacac aaaaaaagcc
     7021 accgaatgcg gtgactctat agggagatta ttatgaaaaa gaaaagttta ggatatttgt
     7081 tacaacaagt taggaggtct tcttgtaact gtctatagta tacccgacct atcttaaaca
     7141 aatcttaaaa atctcttagg accaaacact ttctaaaata tttgtttgtt cacgaccagg
     7201 acctactgag aaagtagaaa tacgaacgcc aaccaattca ctcacacgac gaacatagtt
     7261 acgcgcattc tcaggaagat cttccaaatt gcgaactccg gtaatatctt ctgaccaacc
     7321 tggcaactct tcatagatag gcttgcaacg tttcaattgc tcaagactag ctggatagta
     7381 gtcaatacgt tgaccgtcaa gatcataggc cacacagatt ttcacagtat ccaaaccgct
     7441 caaaacatca atagagttca aagaaaggtt agtaatacca gaaacacgac ggctatgacg
     7501 catcacaact gagtcaaacc aacctacacg acgtggacga ccagttgttg taccatactc
     7561 atgacccact tcacggatac gttctcccac ttcatcaaac aactcagttg ggaaaggacc
     7621 atctcctaca cgactcgtat aagctttaca tacacctaca accttgtcaa tcttgcttgg
     7681 accgacacca gaaccaattg tcacaccacc agctacaggg tttgatgacg taacaaatgg
     7741 ataagtacct tggtcgatat ctagcataac accttgtgca ccttcaaaaa gcacacgttt
     7801 gccattatca agcgcatcat tcaagataac agatgtatct atcacgtatt tcttgatttg
     7861 ttgaccatat tcgtaatatt cttcaaaaat atcatcgaaa acaatcgctt tactgtcata
     7921 caatttttca aaaagacgat tcttttcagc aaggttacgt tctaaacgct cacggaaaat
     7981 atctttatct aaaagatctg caatacgaat tccaacacga gcagccttgt ccatataagc
     8041 tggaccaatt cccttaattg tcgtaccaat cttattgtcg cccttagctt cttcttgcaa
     8101 gcgatccaac tcgatatgat aaggcaaaat aacatgcgca cgatcagaaa tacgcaagtt
     8161 atcagttgtt acaccttcct catgaagata gctcaactct tttacaagag atttaggatt
     8221 tacaaccata ccattcccaa tgacagatat tttttcaggg aagaaaatcc cagatggaat
     8281 caagtgcaac ttaaatttct taccgtcaat cacaatcgtg tgaccagcat tatcaccacc
     8341 ttggtaacgt gcaatcactt ctgcattcgc tgaaaggaag tctgtaatct tccctttacc
     8401 ttcatcaccc cattgggtac ctacaacaac aactgaagtc ataatcttgt ctgagccctc
     8461 aggctcttcc tttctcacat acatggcagg actctcacct gcaattatat cttacaattt
     8521 attataataa aaaatcgcct ttttatcaag aagaaacaat a
//
LOCUS       DAVKMO010000063         8535 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVKMO010000063 DAVKMO010000000
VERSION     DAVKMO010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8535
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.063"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..333
                     /locus_tag="VW361_001830"
     CDS             <1..333
                     /locus_tag="VW361_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9744819.1"
                     /translation="INVKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMT
                     SSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLG
                     LKNKKEEN"
     gene            500..1198
                     /locus_tag="VW361_001831"
     CDS             500..1198
                     /locus_tag="VW361_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9744820.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1195..2247
                     /locus_tag="VW361_001832"
     CDS             1195..2247
                     /locus_tag="VW361_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9744821.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2442..3053
                     /gene="rpsD"
                     /locus_tag="VW361_001833"
     CDS             2442..3053
                     /gene="rpsD"
                     /locus_tag="VW361_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU9744822.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(3147..4313)
                     /locus_tag="VW361_001834"
     CDS             complement(3147..4313)
                     /locus_tag="VW361_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU9744823.1"
                     /translation="MQIKQITKKDGSIVYRANVYLGVDKVTGKDVKTSITGRTKKEVK
                     QKTKEAEIAFLQNGSTRFQASNITTYKELASLWWESYKHTVKPNTQLNVRRLLDNHIL
                     PLFGSYKLDKLTTPLIQNIVNKLADKTNKGEEGAFLYYDSLHALNKRILQYGVVMQAI
                     PFNSAREVILPRNTQKAKREKVKHFDNDELKSFLKYLDTLDLSRYRYYYEITLYKFLL
                     ATGCRINEALALSWSDIDLDNAIVHITKTLNYNQELNSPKSKSSYRDIDIDQATVSML
                     KQYKHRQVQEAWQLGRSETVVFSDFINEYPNNRTLQTRLRTHFKRADVPNIDFHDFRH
                     THASLLLNSGIPYKELQHRLGHSQLSMTMDIYSHLSKENAKKAVSFYETALKSL"
     gene            4582..4764
                     /locus_tag="VW361_001835"
     CDS             4582..4764
                     /locus_tag="VW361_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744824.1"
                     /translation="MDPDKRQKIFSQCKKEGDSLEQRKQEILEKYANKQDKPKSRKND
                     SKGSESHKRKTKSKEF"
     gene            4814..5674
                     /locus_tag="VW361_001836"
     CDS             4814..5674
                     /locus_tag="VW361_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEU9744825.1"
                     /translation="MTTNLVKQKENLEAYIRSTGYNTRGMNVENNHVLIEKPILDSYE
                     DEHQRKELVDLVNVIETRTRGGKYEVTDFESDSLQEISENFVERTESDKKKTISVDYL
                     VKLFSGKLDFSQEQLDDGQYNLTDFLGKKIIKLKRRTRNREIGKILQTAKVQTATSLD
                     DLKSIVSLINPERNVSIVISQSLFSVLEKMKDTSGNYLLKVDKETGTSETFFVDNFLI
                     VDDTTLGNEGDKKGFIGDLENFVTLFDRKKDTLSWVNANDYFRKRLILHTRFDVKKVE
                     EDCGYFIQWN"
     gene            5684..6232
                     /locus_tag="VW361_001837"
     CDS             5684..6232
                     /locus_tag="VW361_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744826.1"
                     /translation="MDINQVFDTLDDLDNKKSKIYSAREQLSEKRKSLLGIQTVSFEN
                     INSFLSNNLESLEKLEKMEKAINSLQEKYNSDFSEAKAVIFEYIFKETKQRMETKKIY
                     KQYRKKLRRILDAYDEIQELKKDVEEIHTGVVREISQKHSLSLYRTEVSPLTVLPFLN
                     PDISGWMDFSKEYRDIKEYLEK"
     gene            6610..7020
                     /locus_tag="VW361_001838"
     CDS             6610..7020
                     /locus_tag="VW361_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEU9744827.1"
                     /translation="MYELSNRDLDGIDIELGRYRTLASKIYLRRQELIHNKKHSTEDY
                     TGGKGKTVYSPTEATIIRIEEDQTLRYLEGFKLIVDTLMENLIDTDLVIFKMRFLEAG
                     VTWEDVAEKLNKTTRYINSRRKVIAKRFIELKGY"
     gene            7396..>8535
                     /locus_tag="VW361_001839"
     CDS             7396..>8535
                     /locus_tag="VW361_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744828.1"
                     /translation="MTAEIGILNKNGVVLAADSAVTLSDGINSKVFNSARKLFTLSRV
                     HSVGIMIYGDASFMGVPWEVIISEYKKSIGNEVLADTAMYINNFVDFLLQFMLIQSND
                     ALVNYIIRQTRSYLKIIHESTQEIADHRSDQGDVITLEIFKNILWEVIEEYSNDISKS
                     ISETEFEYLDGELDLIREQLDEYFNNNEYSDEQLNFLSKTIYKAMLVGFDRNSVTGLV
                     IAGYGVEEIFPSLRQIELSGVFAKRLVWRVITEKEISQNVACHIIPFAQSEMVDTIMN
                     GIDPMLNAFIGQQINEILESNNISDAQEELFETIARVQQQYYINPIFELIGMQPIDEM
                     ASTAKTFIELTSFKRKIVNTLETVGGPVDVLAISKGEGPIWIERKH"
BASE COUNT         2888 a         1323 c         1766 g         2558 t
ORIGIN      
        1 ataaatgtta aagaaacatc agacacagca aatggttcat tatcaccttc taactctggt
       61 tctggcgtga ctccgatgaa tcacaatcat gctacaggta ctacagatag catgcctgct
      121 gacaccatga caagttctac caacacgatg gcaggtgaaa acatggctgc ttctgctaac
      181 aagatgtctg atacgatgat gtcagaggat aaagctatgc taccaaatac tggtgagact
      241 caaacatcaa tggcaagtat tggtttcctt gggcttgcgc ttgcaggttt actcggtggt
      301 ctaggtttga aaaacaaaaa agaagaaaac taatcagcta aggaaataaa tgatggatag
      361 tgggctgact aagattagtt taacaactca atcagcaatc aggactttct ttcaatagca
      421 gattaaaatc atcgtaaaac aataaaaata gtgttatact taaagcagta tagcactgtt
      481 tttatcaaag gagagacaga tgggaaagac aattttactc gttgacgacg aggtagaaat
      541 cacagatatt catcagagat acttaattca ggcaggttat caggtcttgg tagcccatga
      601 tggactggaa gcgctagagc tgttcaagaa aaaaccgatt gatttgatta tcacagatgt
      661 catgatgcct cggatggatg gttatgattt aatcagtgag gttcaatact tatcaccaga
      721 gcagcctttc ctatttatta ctgctaagac cagtgaacag gacaagattt acggcctgag
      781 cttgggagca gatgatttta ttgctaagcc ttttagccca cgtgagctag ttttgcgtgt
      841 ccacaatatt ttgcgccgcc ttcatcgtgg gggcgaaaca gagctgattt cccttggcaa
      901 tctaaaaatg aatcatagta gtcatgaagt tcaaatagga gaagaaatgc tggatttaac
      961 tgttaaatca tttgaattgc tgtggatttt agctagcaat ccagagcgag ttttctccaa
     1021 gacagacctc tatgaaaaga tctggaaaga agactacgtg gatgacacca ataccttgaa
     1081 tgtgcatatc catgctcttc gacaggagct ggcaaaatat agtagtgacc aaacgcccac
     1141 tattaagaca gtttgggggt tgggatataa gatagagaaa ccgagaggac aaacatgaaa
     1201 ctaaaaagtt atattttggt tggatatatt atttcaaccc tcttaaccat tttggttgtt
     1261 ttttgggctg ttcaaaaaat gctgattgcg aaaggcgaga tttacttttt gcttgggatg
     1321 accatcgttg ccagccttgt cggtgctggg attagtctct ttctcctatt gccagtcttt
     1381 acgtcgttgg gcaaactcaa ggagcatgcc aagcgggtag cggccaagga ttttccttca
     1441 aatttggagg ttcaaggtcc tgtagaattt cagcaattag ggcaaacttt taatgagatg
     1501 tcccatgatt tgcaggtaag ctttgattcc ttggaagaaa gcgaacgaga aaagggcttg
     1561 atgattgccc agttgtcgca tgatattaag acccctatca cttcgatcca agcgacggta
     1621 gaagggattt tggatgggat tatcaaggag tcggagcaag ctcattatct agcaaccatt
     1681 ggacgccaga cggagaggct caataaactg gttgaggagt tgaatttttt gaccctaaac
     1741 acagctagaa atcaggtgga aactaccagt aaagacagta tttttctgga caagctctta
     1801 attgagtgca tgagtgaatt tcagtttttg attgagcagg agagaagaga tgtccacttg
     1861 caggtaatcc cagagtctgc ccggattgag ggagattatg ctaagctttc tcgtatcttg
     1921 gtgaatctgg tcgataacgc ttttaaatat tctgctccag gaaccaagct ggaagtggtg
     1981 gctaagctgg agaaggacca gctttcaatc agtgtgaccg atgaagggca gggtattgcc
     2041 ccagaggatt tggaaaatat tttcaaacgc ctttatcgtg tcgaaacttc gcgtaacatg
     2101 aagacaggtg gtcatggatt aggacttgcg attgcgcgtg aattggccca tcaattgggt
     2161 ggggaaatca cagtcagcag ccagtacggt ctaggaagta cctttaccct cgttctcaac
     2221 ctctctggta gtgaaaataa agcctaaaac ccctttacaa atccagctat tcatggtaga
     2281 atagattttg tgtgaaatat cagcaggaaa gcatgaagct cgtcaacagg tgtcttatga
     2341 caagtaacct tggctgttta ggcgaagggc atctgcacga atcagggctt tctaagtgac
     2401 tatttccacc gaaatattat ttatatcagg aggacattca tatgtcacgt tatacaggac
     2461 catcttggaa acaagctcgt cgccttggcc tttcacttac aggtacaggt aaagaattgg
     2521 cacgtcgtaa ctacgtacca ggacaacacg gaccaaacaa ccgttctaaa ttgtcagaat
     2581 acggtttgca attggctgaa aaacaaaaac ttcgtttcac ttacggtgta ggtgaaaaac
     2641 aattccgtaa cttgttcgta caagctacaa aaatcaaagg cggaatccta ggtttcaact
     2701 ttatgcttct tttggaacgt cgtttggata acgttgttta ccgtcttggt ctcgcgacta
     2761 ctcgtcgtca agctcgtcaa ttcgtaaacc acggtcacat ccttgttgac gggaaacgcg
     2821 ttgatatccc atcataccgc gtaactccag gtcaagtgat ctcagttcgt gaaaaatcat
     2881 tgaaagttcc agcaatcctt gaagcagtag aagctactct tggacgtcca gcattcgtat
     2941 cattcgacgc tgaaaaattg gaaggttcat tgactcgctt gccagaacgc gacgaaatca
     3001 acccagaaat caacgaagca cttgtcgttg aattctacaa caaaatgctt taattttaag
     3061 aaatatctta cagaaagcct acaacagtgg gctttttgct ttgtcttaaa atgttgattt
     3121 ctgggtttgt tcagttattt gttcagttat aaacttttta gtgcagtttc atagaacgaa
     3181 actgcttttt ttgcattctc ttttgagagg tgactgtata tatccatggt catagataat
     3241 tgggaatgtc ctagacggtg ctgaagttcc ttgtaaggta ttccagagtt aagcaagaga
     3301 ctagcgtgag tatggcgaaa atcatgaaaa tcaatgttag gtacgtcagc acgtttaaag
     3361 tgagttctta acctggtttg tagagttcga ttattggggt actcatttat gaagtcagaa
     3421 aagactacag tttcagagcg cccaagttgc caagcttctt gtacttgtct atgtttgtac
     3481 tgcttcagca tactaacagt cgcttgatct atatcgatat cacgatagct agattttgat
     3541 ttaggactat tgagttcttg attatagttt agtgtttttg tgatatgcac aatagcatta
     3601 tctaagtcaa tatcagacca tgataaggct aaagcttcat tgatacgaca accagtagca
     3661 agtagaaact tataaagtgt aatctcataa taatagcgat acctacttag atccagagta
     3721 tctaagtatt taagaaagct ttttaattcg tcattatcaa agtgctttac tttttctcgc
     3781 tttgcttttt gtgtgttgcg aggtaatatt acctcacgag cagaattaaa cggtatagct
     3841 tgcataacta caccatactg taaaatacgc ttatttaaag cgtgtaagct atcgtagtat
     3901 agaaaagcgc cttcttcccc tttattggtt ttgtcagcaa gtttattgac tatattttga
     3961 ataagtggag tagttagttt atccaactta taagagccaa ataaaggtaa gatatggtta
     4021 tctagcagtc ttctaacgtt taattgtgtg ttaggtttta ctgtatgctt gtaactttcc
     4081 caccataagg aagctaattc cttgtaagta gtaatatttg aagcctggaa tctagtagat
     4141 ccattttgta aaaaagcaat ttcagcttct tttgtctttt gcttaacttc tttttttgtc
     4201 cttcctgtta tgcttgtctt tacatctttt ccagtgactt tatcaacacc aagatagaca
     4261 ttagcacgat atactattga accgtctttt tttgtgattt gttttatttg catagtattc
     4321 ttttccatca gcaggcaagc aattagaaaa ggttttgagt ttataccatg ctaggagcta
     4381 cgagaacccc tctattttcg attttaagag aacgaacggt aaaatgtacc aggtaagaaa
     4441 atgaagcgat tatggaactt ataaagggta ttaattagat aatcttctca aataccattg
     4501 tggcttgaat gcggtcacca ccgcctaaac ctttgcttcc accattggcg gttgtgatgg
     4561 tatgcaggtg ataagttttc tatggatcca gataaaagac agaaaatctt ttctcagtgt
     4621 aaaaaagaag gtgatagctt agaacaacgg aaacaagaaa tactagagaa atatgctaac
     4681 aaacaagaca aaccaaaatc tagaaaaaat gattctaaag gctcggagag tcataaaaga
     4741 aaaactaaga gcaaagaatt ttagaaaaaa ttataaacaa aaatcagata ttaaaagatg
     4801 aaggagcaaa aaaatgacaa ctaacttagt taaacaaaaa gaaaatttag aagcttatat
     4861 ccgaagtaca ggttataaca ctagagggat gaatgtagaa aataatcatg tactcattga
     4921 aaaaccaatc cttgatagtt acgaagatga acatcaacgt aaagaactgg ttgatctagt
     4981 aaatgttatt gagactcgta cccgtggcgg gaagtatgag gtaactgact ttgaatctga
     5041 ttcattacaa gaaattagtg aaaattttgt tgagagaaca gaatcagata aaaagaaaac
     5101 tatcagcgtt gattacttag ttaaattatt cagtggaaaa cttgattttt cacaggaaca
     5161 attagatgat ggccaatata atttaacgga ttttcttggt aagaagatta ttaaattaaa
     5221 acgtagaaca cgaaatagag agattgggaa aattctccaa actgcgaaag tacagaccgc
     5281 tacaagtctg gacgacttga aatctattgt ttctttaatc aatccagagc gcaatgtatc
     5341 tatagttatt agtcaatcac tatttagtgt cttagaaaaa atgaaagaca cttcaggaaa
     5401 ttatcttctt aaagttgata aagagacagg aacgagtgaa acattctttg tagataactt
     5461 tttaattgta gatgatacga cattagggaa cgaaggcgac aaaaaaggat ttatcggaga
     5521 tctagaaaac tttgttactt tgtttgatcg aaagaaagat acacttagtt gggtgaatgc
     5581 gaatgactat tttagaaaac ggttgatttt acatacccga tttgatgtaa aaaaagttga
     5641 agaagattgt ggttacttta ttcaatggaa ctaggaggaa gaaatggata ttaatcaagt
     5701 atttgataca ctggatgatt tagataataa aaaaagtaag atttattcag cacgagaaca
     5761 gttaagcgaa aaaaggaaga gtcttttagg cattcaaaca gtttcatttg agaatataaa
     5821 ttcttttttg tcaaataact tagaatcttt agaaaagctg gaaaagatgg aaaaagctat
     5881 taattctctt caggaaaaat ataatagtga tttttcagaa gctaaagcag tcatctttga
     5941 atacattttt aaagaaacta agcaacggat ggaaactaag aagatctata aacaataccg
     6001 aaagaaactt agacgaattc tggacgcata tgatgaaatt caagaactaa agaaggatgt
     6061 agaagaaatt catacaggtg tagtcaggga aataagtcag aaacattctc tatcgctata
     6121 tcgaacggaa gtaagtccgc ttactgtcct accattctta aaccctgata ttagcgggtg
     6181 gatggatttt tctaaggaat atcgggacat taaagagtat ttagaaaaat agggaacaaa
     6241 ttaagtaagg ctagtgatat atggctgaaa cagaagagat atcgctagtc ctacttttat
     6301 gctttactaa gtttcacata acaaagtaag cataaactaa aatagagtat aggcttggaa
     6361 gtcatatata tcagtaagtt acagaatgga gtgagtttca cagaatgtaa gatatgagaa
     6421 acttagggga taaattaaag aaatttccct tgaacttgtc atattgaaga gttgtcaaac
     6481 ttaaaacaat gatacctggt aagtggagtg ttggaaggct tttagcgctt tttgtcagtt
     6541 tgacagaatt tacaatttga caaattgaaa gataaaaaaa tttttaaatt taagtggagg
     6601 tacttgccta tgtacgagtt gagtaacaga gacctggacg ggatagatat tgagttagga
     6661 cgatatagaa cgcttgctag taaaatttat ttaagaagac aggaactgat acataataag
     6721 aaacatagca ctgaagatta tactggtgga aaaggcaaga cagtatatag tcctaccgaa
     6781 gcaactatta ttagaattga agaagaccaa acactaagat atttagaagg tttcaaacta
     6841 attgtagata ccttgatgga aaatctgatt gatactgatc tagtcatctt taaaatgaga
     6901 tttttagaag ctggtgtgac ttgggaagat gtggcagaga aactaaataa aactactcgt
     6961 tatataaata gtcgaagaaa agtaatcgct aaaagattta tagaactgaa aggatattga
     7021 ctccccccac gttgaaaaaa attttttgaa tactttgaga accggtgaag ggaacttttt
     7081 ctaagtcgga gacctccaga caaaaagggg gtaaaaactt gttgatttat aaggtgaagg
     7141 ctagtttttt gaaattaaac atatgcattc aaaagtcatt gaaataaatg aggaggttaa
     7201 actgaagata atttttctag attaaagtga agctatgata tattgttaga aattggagat
     7261 gtgtttgcat agttaaaaga atgtactttt agtatgaatt gtattataat tagttaaagg
     7321 gaattgttgt ataaattgaa aaatatttaa tgatttttaa ctgttaagtt atgtaaaata
     7381 attggaggct caattttgac tgcagaaatt ggaatactaa ataagaatgg agttgtttta
     7441 gctgcagata gcgcggtgac tttatctgac gggattaact ccaaagtgtt taatagtgct
     7501 cggaaattat ttactttatc tagagtgcat tcggttggaa ttatgattta tggagatgcc
     7561 tcctttatgg gtgtaccgtg ggaagtaatc ataagtgagt ataaaaagtc aattggcaac
     7621 gaagtactag ctgacacagc aatgtacatt aataattttg ttgatttttt attgcaattt
     7681 atgctaatac aaagtaatga tgccttggtt aattatataa ttagacagac tagaagttat
     7741 ttaaaaataa tacacgagag cacccaagaa atagctgatc atagatcaga tcagggagat
     7801 gtaataactc tagaaatttt taaaaatatt ttatgggaag ttatagaaga atattcaaat
     7861 gatatctcca aatcaatatc tgaaactgaa tttgaatatt tagatggcga acttgattta
     7921 atacgggaac aactagatga gtactttaac aataatgaat actccgatga gcaactaaac
     7981 tttttatcta aaacaatata caaagcaatg ttagttggtt ttgatagaaa ttctgtaaca
     8041 gggttggtaa ttgctgggta tggtgttgaa gaaatttttc catcccttag acaaatagag
     8101 ttaagtggtg tatttgctaa acgccttgtc tggcgtgtaa ttaccgagaa agaaattagc
     8161 caaaatgttg cttgtcatat tattcccttt gctcaatccg aaatggtaga tactataatg
     8221 aatggcatag atccaatgtt aaacgcattt ataggacaac aaattaatga aattttggaa
     8281 agtaataata tatcggatgc acaggaagag ttgtttgaaa ctatcgctag agtccaacaa
     8341 caatattata taaatccaat ttttgagttg attgggatgc aacctattga tgagatggct
     8401 tctactgcaa aaacattcat tgagttgact tcttttaaga gaaagattgt gaatacactt
     8461 gaaacagttg gaggaccagt ggatgtttta gctatttcta aaggggaagg tcctatctgg
     8521 attgaaagaa aacac
//
LOCUS       DAVKMO010000064         8514 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVKMO010000064 DAVKMO010000000
VERSION     DAVKMO010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8514
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.064"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            9..1010
                     /locus_tag="VW361_001840"
     CDS             9..1010
                     /locus_tag="VW361_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9744829.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            1618..1695
                     /locus_tag="VW361_001841"
                     /pseudo
     CDS             1618..1695
                     /locus_tag="VW361_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            1908..2063
                     /locus_tag="VW361_001842"
     CDS             1908..2063
                     /locus_tag="VW361_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744830.1"
                     /translation="MEKLQFFLSQRACGCWKQAEKAVKLGSSETREENIILKGVPFIA
                     QPVTGDI"
     gene            2198..3559
                     /gene="trpE"
                     /locus_tag="VW361_001843"
     CDS             2198..3559
                     /gene="trpE"
                     /locus_tag="VW361_001843"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU9744831.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYIVFDHKKEKIHVIEDAFYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            3556..4122
                     /locus_tag="VW361_001844"
     CDS             3556..4122
                     /locus_tag="VW361_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU9744832.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            4133..5137
                     /gene="trpD"
                     /locus_tag="VW361_001845"
     CDS             4133..5137
                     /gene="trpD"
                     /locus_tag="VW361_001845"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU9744833.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            5134..5901
                     /gene="trpC"
                     /locus_tag="VW361_001846"
     CDS             5134..5901
                     /gene="trpC"
                     /locus_tag="VW361_001846"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU9744834.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGIALMQAENVVQRIKELQIDKG"
     gene            5888..6487
                     /locus_tag="VW361_001847"
     CDS             5888..6487
                     /locus_tag="VW361_001847"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU9744835.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKNGISRTK"
     gene            6465..7688
                     /gene="trpB"
                     /locus_tag="VW361_001848"
     CDS             6465..7688
                     /gene="trpB"
                     /locus_tag="VW361_001848"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU9744836.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGRDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            7681..8457
                     /locus_tag="VW361_001849"
     CDS             7681..8457
                     /locus_tag="VW361_001849"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU9744837.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(8429..>8514)
                     /locus_tag="VW361_001850"
     CDS             complement(8429..>8514)
                     /locus_tag="VW361_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU9744838.1"
                     /translation="KKKERLPFVPFLLLATCLIIFGKLLLV"
BASE COUNT         2527 a         1601 c         2045 g         2341 t
ORIGIN      
        1 ggactgaaat gaaaaatata aatgggaaaa aggtaactat ttatgatatt gcacgtttat
       61 caggtttttc tccaaaaaca gtttcacgag ttattaatgg tggagtaaat gttaaagaag
      121 aaacttatca agcgattcaa aaagttatag aggaattgtc gtatattcca aatgcgtatg
      181 caaaaaattt aactaaaaaa gaagctataa atatattgat ttctgtaaaa aaaatcgact
      241 cttttccttt aatttggttt catacgctgt tagataaagt gttacggacg tgtaaagaat
      301 ttggtgttaa tgctatagtt gagtactttg gagaggagga tacaattagt aattcaatta
      361 tatcaagcac aggtagccta gtagatggtg ttattgtttt ttatgaaagt gtagatgata
      421 tcagaattca gtatttaaag aagaaccata tgccttttct tgttttcggt gaatctcaaa
      481 cgtctggagt agtctatgta tctaataata attttcaagc tacttatgat atgatgaaag
      541 ctgtaactga agaaaaattt aaaaatatgt ggttgcttat gggaggagaa tctcatgtta
      601 ataaggatcg tgaaagaggt gtgcgttctt ttctgaatga taaaaattac tttatggatt
      661 taaaagtcat ttatggctta tctacaattg attcagttta ttcttatgca atgcagcact
      721 tgactaccca aaattatccg gacattattt ttgtttcagg agatgaaaag gttcagggct
      781 tgattcgtgc gtgctatgag aaaggaattc ttattccaga tgatatttct atcattggat
      841 ttgataatat tcctatttct cagtattata ctccagcttt gtctacaatt gctcccaatt
      901 atgttaaatt ggctaaagaa atgatagaag gtgttttagc aattattaaa ggggaaagtg
      961 tcacatctgt tgaagtttct cctaaatttg ttaggagaca gagtttctag tattgtttaa
     1021 ttcttgaaaa tcctagtgga aaatatggag tgttctaaaa taagttctgt ttagcctcca
     1081 ttcagtttct attgagttgg atccaatttc taacgagtgg gacatgttca tgttcgatct
     1141 aaggaagaca tggtcacatt cgaatgatat tttcaaaaaa atcgtaaaaa agtcttgaca
     1201 aagaaaaaac aaagtattaa aataagttca acaaatcaga aaagtaacta tttttgatct
     1261 tcagggagcc tgtggtgatt gtgaataggt ggttggaagt agtgaaagtg ggctgatttt
     1321 gaaaatgaat ttgaaacaat gaaaattcgg tgcgcacacc ttacagtgca gcttgttgtt
     1381 aaacaaggca gagatgtaaa gggatagtcc ctttataatt gaggtggcac cgcgttacca
     1441 acgccctcac acggaagtat attctgtgtg tgggcttttt tctatccgtc gtttggttta
     1501 tcttttatta gggccttaag tcgctttgat gaacttgagt tctatctaca gctccttgcc
     1561 tcctactaaa agtaaacaaa aaggctggac taatacgaaa aaagctagta atactcaatg
     1621 aaaatcaaag agcaaactag gaaactagcc gcaggctgct caaaacactg ttttgaggtt
     1681 gcagatagaa ctgacgaagt cagctcaaaa cactgttttg aggttgcaga tagaactgac
     1741 gaagtcagta accaatacct acggcaaggc gacgttgacg cagtttgaag agattttcga
     1801 agagtataaa ggtgtaccga gatgaacatc tcttcatcaa tgtctctggt cgtggaggca
     1861 aggacctagc tgcgattgca gactacctag aagctaaaaa ataatagatg gaaaaattac
     1921 agttctttct ctcacagaga gcttgtggtt gctggaaaca agcagagaaa gctgtaaagt
     1981 tgggttcatc tgaaacgaga gaagaaaaca tcattctcaa gggagtgccc tttatcgcac
     2041 agcctgttac aggagatatc tgagacagga atgagagata ggagaaatcc tataattgag
     2101 gtggcaccgc gaatttcgtc ctcacgcaag ttattttgcg tggggatttt tcatacagtc
     2161 gctacgaact agaattagaa ctgaaaggga aattacaatg gaacgaatca ttcatggaga
     2221 tgtcttatca ccaatcttgg cttatatgcg cttaaagggg caacacaagg ttatcttaga
     2281 gagtattccg agagacaagg aaacagctcg tttttctatc ctagcctata atcctgtttt
     2341 tgagattaag tttgaaaatg gagttcttta tcaaaatggt caagtgattg atcgggatcc
     2401 cttggatttc ctttatgaag tgattcataa gagtcagcac cattcagagc taccttttgg
     2461 tggtggagcc attggttttg tgggttacga tatgatttcg ctttatgaag aaattggtca
     2521 aatccctgag gatacaattg ggacgccaga catgcatttc tttgtctatg agagctatat
     2581 agtctttgac cacaagaagg agaagataca tgtcatagag gatgcatttt atagtgagcg
     2641 cagtcaagag gccttggaaa aatccttgaa ccaagtgctt gaggaattac gcattcctgc
     2701 tccaaatgaa tttgaagact tggatttatc accacttgac ttcaaaccgc atatcgctcc
     2761 acataagttt gagggaatgg tagaaacagc tcgtgacttg attcgtaacg gcgatatgtt
     2821 ccaatgtgta ctcagccagc gtttctcagc agaagttact ggaaatccat ttgacttcta
     2881 cagaaatctc cgcgtaacta atccttctaa ttacctttat ttctatgatt ttggggatta
     2941 tcaaatcatc ggagctagtc cagaaagttt ggtttctgtc aaaaatggca tcgtgacaac
     3001 caatccgatt gcagggacgc gaccaagagg ggctacggat gaagaagaca aggccttggc
     3061 gactgacctc ctctctgatg agaaggaaac agcagaacat cgaatgttgg tagacttggg
     3121 gcgtaacgat attggccgca tctctgaaac gaccagtgtc caagtcacta agtatatgga
     3181 agtggagctc ttccgctacg tcatgcattt gaccagcgta gtcaaggggc gtttgcttgc
     3241 agaactcact gccatggatg ccttgaaagc aacgcttcct gctggaaccg tttctggagc
     3301 accaaagatt cgagcgatga gacgtatcta tgaactggaa acggaaaaac ggggagtata
     3361 cgctggggca atcggctact tgtctgcgac gggtgatatg gatttggcca tcgccatccg
     3421 aaccatgatt ctcaaaaatc aaagagccta tgtgcaggct ggggcaggga ttgtctacga
     3481 ctctatcgcc caaaacgaat accaagaaac cattaacaaa gcaaaatcta tgactagaat
     3541 tggagaacta agaccatgat tttattgatt gacaactatg attcttttac ctataacttg
     3601 gcccaataca ttgggaattt tgcagaagtt caggttctga gaaatgatga ttccaagctg
     3661 tatgaagaag ctgaaaaagc agatggtctg gtcttttctc ctggtcctgg ttggccagtt
     3721 gatgctggaa agatggaaga catgattcgt gattttgcag gcaagaagcc gattcttggg
     3781 atttgtttgg gccaccaagc cattgcagaa gtctttggtg gtaagctagg tttggctcca
     3841 aaagtcatgc atgggaaaca gagcaatatc aactttgaag cgccatctgt tttgtatcaa
     3901 ggtattgagg atggccgtgc ggtcatgcgt tatcacagta ttttgattga ggaaatgcca
     3961 gaagactttg aagtgacagc tcgttcgact gatgaccaag ccatcatggg gattcaacat
     4021 aaaaacctac cgatttatgg cttccagtac catccagaga gcattggaac gccagacggc
     4081 ttgtcttcta ttcggaattt tatcgaggag gttgtaaagt gaggaaacta ggatgaaaga
     4141 gattattgaa aaactagcaa aatttgaaaa tttatcaggt gtggaaatga cggatgtcat
     4201 tgagcgtatc gtaactgggc gtgtaactga agcgcagatt gcttctctcc tcttagctct
     4261 taagatgaag ggggaaacac ctgaagaacg cacagccatt gcccaagtca tgagaggaca
     4321 tgcccagcat attccaactg agattcatga tgccatggac aactgtggta caggtgggga
     4381 caagtctttc agttttaata tttccacaac tgcagccttt gtcttggctg gtggcggtat
     4441 tcacatggcc aaacacggta accgctcgat atcttctaaa tctggttccg cagatgtcct
     4501 cgaagccttg ggaatcaatc ttgacctcaa accagctgaa ctaggtaagg tctttgataa
     4561 aactggaatc gtctttctct tcgctaaaaa tatgcaccca gctatgaaat acatcatgcc
     4621 agctcgtttg gaattgggaa ttccaacgat tatgaacttg actggtccac tgattcatcc
     4681 aatggcttta gaaacacagc ttcttggaat tagtcgtcca gaactcctag aaagtacagc
     4741 tcaggttttg aaaaatatgg gtcgcaaacg tgccatcgtg gttgctggac cagaagggtt
     4801 ggatgaagct ggcttgaacg gaacaaccaa gattgcactt cttgaaaatg gcgaaatcag
     4861 cttgtcaagc tttactccag aggatttggg aatggaaggc tatgctatgg aagatattcg
     4921 tggtgggaat gctcaggaaa atgcagaaat tttgcttagc gttctgaaaa acgaagcaag
     4981 tccattcttg gaaacgacag tcttgaatgc tggtcttggt ttctatgcta atggtaagat
     5041 tgatagcatc aaggaaggag ttgccttggc tcgtcaagtg attgctagag gcaaggccct
     5101 tgaaaaactc agactgttac aggagtacca aaaatgagtc aggaattttt agcacgaatc
     5161 ttagagcaga aggcgcgtga ggtggagcag atgaagctgg agcaaatcca gcctctgcgc
     5221 cagacctatc gcttggcaga atttttgaag aatcatcagg accgcttgca ggtaatcgct
     5281 gaggtcaaga aagctagccc tagtttggga gatatcaatc tcgatgtgga tattgtgcaa
     5341 caggcccaga cttatgaaga aaacggagca gtgatgattt cggtgttgac agatgaggtt
     5401 ttctttaaag ggcatttgga ttatctacgg gaaatttcca gtcaggtaga gattccgacg
     5461 ctcaacaaag actttatcat cgatgaaaag caaatcatcc gcgctcgcaa tgcaggtgcg
     5521 acagttatct tgctcattgt ggcagccttg tccgaagaac gcctcaagga actgtatgac
     5581 tacgcgacag agcttggtct ggaagtctta gtggagactc acaatctagc tgaactagag
     5641 gtagcccaca gacttggtgc tgagattatc ggggtcaaca accgcaactt gactaccttt
     5701 gaggtcgact tgcagaccag tgtagattta gccccttact ttgaggaagg tcgctattac
     5761 atttctgaat ctgccatttt cacagggcag gatgcggaac gactagcccc atactttaat
     5821 ggaattttgg tagggatagc tcttatgcag gcagaaaatg tggtccagag aatcaaggag
     5881 ttgcagattg acaaaggtta aaatttgtgg actatcgacc aaagaagcgg tggaaacagc
     5941 cgtttcagca ggagccgact atatcggttt tgtctttgca cctagtaaaa gacaggtgac
     6001 tttagaagag gcagctgagt tggcaaagct tattcctgca gatgtgaaaa aggttggagt
     6061 atttgtttca ccaagtcggg tagaactgct ggaagcgatt gacaaagttg gcttggactt
     6121 ggttcaagtt cacggtcagg tagcagatga tttatttgag aatttgcctt gtgccagtat
     6181 tcaggctgtg caggtagatg gaaatgggca tgtccctaat tctcaggcag attatctact
     6241 ctttgatgcc cctgtggcag gaagtggcca gccctttgat tggggtcaac tggatacgac
     6301 tggactagca cagcccttct ttatcgcagg tggccttaat gaagataatg tagtaaaagc
     6361 aattcaacac tttactccct atgcagtaga tgtatcaagc ggagtggaga cagatggaca
     6421 aaaagatcat gaaaagatta gaagatttat agagagggta aagaatggca tatcaagaac
     6481 caaataaaga tggattttac ggaaaatttg gcggacgttt tgtcccagaa acattgatga
     6541 cagcagtttt ggagttggag aaggcctacc gtgaaagtca ggcagaccca agtttccaag
     6601 aggaattaaa ccaacttttg cgccagtatg tgggacgtga aactcccctt tactacgcaa
     6661 aaaacttgac ccagcatatc ggcggagcca agatttatct caaacgggaa gaccttaacc
     6721 atacaggagc ccacaagatt aacaatgcct taggacaagt ttggcttgcc aaacgcatgg
     6781 gtaaaaagaa aattatcgca gaaactggtg ctggtcagca cggtgtggca actgcaactg
     6841 ctgcggccct ctttaacatg gaatgtacca tctacatggg tgaggaagat gtcaaacgcc
     6901 aagccctcaa tgtcttccgt atggagcttt tgggagctaa ggtcgaggcc gtgacagatg
     6961 gttcgcgcgt gctcaaggat gcggtcaatg cagctcttcg ttcatgggta gctaatatcg
     7021 atgataccca ctatatcctt ggttctgcct tggggcctca tccatttcca gaaatcgttc
     7081 gtgacttcca aagtgtcatc ggtcgagagg ctaaacaaca gtaccgtgac ttgacaggtc
     7141 gagatctgcc agatgcccta gtagcctgtg ttggtggtgg gtcgaatgct atcgggctct
     7201 tccatccctt tgtagaagat gagtcagtag ctatgtatgg aactgaagca gcagggcttg
     7261 gtgtggatac agagcaccac gctgctacct tgaccaaggg tcgtccggga gttcttcacg
     7321 gttctctcat ggatgtgctc caagatgccc atggtcaaat tcttgaagcc ttctctatct
     7381 cagcaggttt ggactatcct ggtattggtc cagaacattc tcactaccac gatatcaaac
     7441 gtgccagcta tgtccctgtg acagacgaag aagccttgga aggattccaa ctcttgtctc
     7501 gtgtggaagg gattatccca gccttggaat ctagccatgc tatcgctttt gcggtgaaat
     7561 tggccaaaga acttggacca gaaaagtcta tgattgtctg cctatcaggt cgtggggaca
     7621 aggatgtggt tcaagtcaaa gaccgcttgg aagcagatgc agcaaagaag ggagaagctc
     7681 atgcctaaga cactaacaga aaaattaaat gctataaaag cagctggaaa aggaattttt
     7741 gttccctata tcatggctgg agaccacgag aaaggtttgg atggactagg agaaacaatc
     7801 cactttctag aagatttggg tgtctctgca attgaagtgg gtattccctt ttcagaccct
     7861 gttgcagatg gacctgttat cgaagaagct ggcttgcgca gtttagccca cgggacctct
     7921 acccaggctt tagttgaaac cttgaaaacc attgaaacag agattccact ggtcatcatg
     7981 acctacttca accccctctt tcagtacggt gtggagaact ttgtcaaaga tctggctgat
     8041 acagctgtga agggcttgat tatcccagac ttgcctcatg aacatgccaa ctttgtagaa
     8101 ccatttttgg cagatacaga tatcgccttg attcctttag taagcttgac cacaggaatt
     8161 gagcgccaga aagagttgat tgaaggggcg gagggattcg tctatgccgt tgccatcaat
     8221 ggagtgacag ggaaatcagg caattaccgt gcagatttgg acaagcactt ggcgcaactt
     8281 catcaagtgg ccgacatccc agtcttgaca ggttttggtg tatctagtca agccgatctg
     8341 gaacgcttca atgcggtgtc agatggtgtt atcgtcggtt caaaaatagt aaaagctctc
     8401 caccaaggag agccgattca ggattttatc agacaagcag tagcttacca aaaataatca
     8461 aacaagtagc aagtaagagg aaaggcacga aaggaagtct ttcctttttc tttt
//
LOCUS       DAVKMO010000065         8203 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVKMO010000065 DAVKMO010000000
VERSION     DAVKMO010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8203
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.065"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..608
                     /locus_tag="VW361_001851"
                     /pseudo
     CDS             1..608
                     /locus_tag="VW361_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(1346..1606)
                     /locus_tag="VW361_001852"
     CDS             complement(1346..1606)
                     /locus_tag="VW361_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744839.1"
                     /translation="MRERSATGAQDLSKSIKKHLNDITRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1665..2216)
                     /locus_tag="VW361_001853"
     CDS             complement(1665..2216)
                     /locus_tag="VW361_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744840.1"
                     /translation="MPANTKVIFQETFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYTLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(2206..3210)
                     /locus_tag="VW361_001854"
     CDS             complement(2206..3210)
                     /locus_tag="VW361_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744841.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLSISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQI
                     KSVSNLLYGGAYALSHSTFLAETDENTSYVIWQRKFNQLSLPLSQHILKGKMLEIWKY
                     RPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS
                     "
     gene            complement(3618..4043)
                     /locus_tag="VW361_001855"
     CDS             complement(3618..4043)
                     /locus_tag="VW361_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744842.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(4172..4530)
                     /locus_tag="VW361_001856"
                     /pseudo
     CDS             complement(4172..4530)
                     /locus_tag="VW361_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835110.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4576..4782)
                     /locus_tag="VW361_001857"
     CDS             complement(4576..4782)
                     /locus_tag="VW361_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744843.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTHFSLIAVNSDMPLGR"
     gene            complement(4769..4930)
                     /locus_tag="VW361_001858"
     CDS             complement(4769..4930)
                     /locus_tag="VW361_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9744844.1"
                     /translation="MYMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(5321..6277)
                     /gene="lytA"
                     /locus_tag="VW361_001859"
     CDS             complement(5321..6277)
                     /gene="lytA"
                     /locus_tag="VW361_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU9744845.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(6653..8023)
                     /locus_tag="VW361_001860"
     CDS             complement(6653..8023)
                     /locus_tag="VW361_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9744846.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLDQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILLQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQSSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIAQGLRIGSRLSISWAVFVCIF
                     LFFASPALISFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
BASE COUNT         2649 a         1662 c         1323 g         2569 t
ORIGIN      
        1 aacttatgaa gaaattgcgg ctgattttgg tatccacgaa agcaacttac tccgtcggag
       61 ccaatgggtt gaagtaactc ttgttcaaag tggttttacg atttcaagaa ctcctctcag
      121 ttctgaggac acggtaatga ttgatgcgac ggaagtaaaa atcaatcgcc ctaaaaaaag
      181 aattagcgaa tgattctggt aaaaagaaat gccacgctat gaaggctcaa gcgattgtca
      241 caagtcaagg gagaattgtt tctttggata tcactgtgaa ctattgtcat gatatgaagt
      301 tgttcaaaat gagttgcaga aatatcggac aagctggtaa aatcttggct gacagtgatt
      361 atcaagggcc catgaagata tatcctcaag cacaaactcc acgtaaatcc agcaaactca
      421 agccgctaac agctgaagat aaagcctgta accatgcgct atccaaggaa agaagcaagg
      481 ttgagaacat ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc
      541 atcgtaaacg ctttggatta cgaatgaatt tgattgctgg tattatcaat catgaactag
      601 gattctagtt ttgcaggaag tctattatat atgcacagac atatgaaatc tttttgagac
      661 agcagttatg atatatttat ccattcacaa catcttctgt actaatacta caatattggt
      721 acattttgat tacacaatcg tttcaaaaaa tatgatggaa gcctgagtat tttatagtaa
      781 ttcccttcct atcaactaga tcaaccagtt gagtgttgaa tgttgaaaca ccctagcctc
      841 agcaaaggac tatgatcagc atttcctagc caataggacg ctccaaatca cctattctaa
      901 gtccatcact agcttggtca gtaagataca gactgcaagg cgagactgat gtggttgatg
      961 agattttgga agagtattac aatcatagat tcaccagtag acttgaccgc agatttaact
     1021 atagtagatt gaaactagaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     1081 tgactgtcct gatcaatttg tcctgttctc gtttcatttt actatactaa aaaaccacct
     1141 gaaacaaatc aagtgactag aggataaaaa caaaaactgg gcaaaaagtt ttgaaaagca
     1201 aaaaacgcat aatatcaggt cttgaaaaac cttgatacta tacgtttgat tgtgggaaga
     1261 ttgacttcat tttctcctga aattgaagtt ttttctagtt tccagatata aacgaattca
     1321 atatagccat ctcgctacaa ttattttaac catcgagaaa atttttcaga atttcaaaaa
     1381 tttcattttg atccaatgaa atgtcatcat tttgaagaat agttgacttc acaggctcta
     1441 attctatcac aaagcggtgc atgtctgctt ttaccgcact acttgatgtt atagccgata
     1501 acttttcatc tcctagcaag gaagctgtca aacgggtaat gtcattcaaa tgctttttaa
     1561 tggacttact taaatcttga gcacctgtag cagagcgctc tctcatatcc agccaagctt
     1621 tagccttaaa aataattaat actcaatgaa aatcaaagag caaactagga agctagctgc
     1681 aggctgctca aaacactgtt ttgaggctgt agatggaagc tgacgtggtt tgaagagatt
     1741 ttcgaagagt atagaccaca attactcaat accgaatacc cctgaatggt ttctttttca
     1801 tgcaccaata tattataata atcttcatcc aataataagg ctgataaact agcatcttgg
     1861 tcaaaatgta agggaatttc tcggccgtcc ttctttaatg tatattctgg taagatacta
     1921 aatagttcaa tcatagaagg aaactcagga ttagttgttg taaatcgaaa aagctgcgct
     1981 ttctcatctt tctgacttcc ttgatactct cccaattcta aaaaatgatt caaggtagta
     2041 taaaattcct tattttttac ttcatcaatg atgaccatat cataatcttt tgttgtgcga
     2101 cttttaaatc cttgcgaatc caatacgata gaggtagcag ttcccccaat cagaacataa
     2161 tagttctgaa aatccgcaaa cgtttcttga aaaataactt tcgtattagc tggcatcatc
     2221 ttctcccaga tactgtaata tcatattttc tagtgcttca ctctcttcct ctatacgtgg
     2281 gtcatcatca tcttttaagg tcaaataaag agaaatcgga tctacaaatt gtttatcatg
     2341 attattttta aaatcattcc aaaactcaga tacaaaagga cgatatttcc atatctctag
     2401 catctttcct tttaaaatat gctgagaaag tggcaaggat aactgattga attttctctg
     2461 ccatatgaca tagctagtat tttcatccgt ttcagctaaa aaagttgaat gcgacaaagc
     2521 ataagcacca ccatatagaa ggttagaaac agattttatc tgctttatat cgccatctgg
     2581 caataaaatc cgttttttga tgggattaaa taaacatgac acggatttta agaataattc
     2641 tttctttgac accgtatatg tgtaaagctt attttgctta ttttgcttgt ttaaccaata
     2701 taaagcttta aaagtcctca aacacctata aattgttgag tttggaagtc cagtgacttg
     2761 tgaaagcaaa tcaacatcta ctactttttg accttttgtc aataaaaagg caatccacgt
     2821 taattgttcg ctaggtgtta attccttagg gacttcagta tcattcgcat tgagtactag
     2881 tcccaatgga gggaagaaga ggtttccctt aaagtctaca aacggaactc tagcttgaag
     2941 taattgcttt ttttcactgt ctgataactt cgaaaacacc aaaacaacat ccatattggc
     3001 tttttcaccc atagtgcgag cctgagtaac aaatgaactc aaactccccc ttctcttttc
     3061 tttaatcaat aaaaatgatt ccttatgaaa agtcatttga gtatactcaa acctttttac
     3121 aaaactgatt gataaagtca aagtcagttc ctcaatactg acatcaacat aaaaggattg
     3181 aaaaattgac attatctttt tgacattcat gttttttcct tattctatca tttttattat
     3241 attttatcat tcggtataat aaaatataag ttttttgata aaataaccaa aaactactcc
     3301 ctatcccctc tcacactacc ctacatatcg tttgacatgc gactgatagt tcaggaaaac
     3361 ttcaaggaga acttttctct catccactat gcaggactta ctatttcact tctactccta
     3421 taggctcaat ttgacacttt tctttttcga attgctcata tgcctcctga atagtgagtt
     3481 cgatttatcc aaatttattt ttgtctattt tgatgaatac ttccacgaag atagtctgaa
     3541 aatgaatttg caccaatttt ccttctcttt ttaagcatat tattccagat atgattgccc
     3601 tcttgttcag taataaatta cgctttaaac gcttcaatca gtatatctcc tgttgtcata
     3661 tgttctaaag aaaattcttc tacatatgat ttaacatctc ttaggttatt acttcctaat
     3721 atcccattat gctttttcgc taaggaaata gaagccgctt ctcccttacc aataatcttg
     3781 ttactatcat gatttcttgt taaatctcta tataatgcgt attcttcagt tccaatgtct
     3841 atgctcacaa tctcagctga acccttagct accaactgat ctatcctaga ttttaaatgg
     3901 ggaattgtag gtatattgat ttcatcatac acctcttgtg gaataacaat tttacccgaa
     3961 tagagctttt ctaaaagatg ttcagtacca acccataaaa atactgaaat acaatctgca
     4021 tcaataaata cacgactagt caaacgacaa ctcccccctc ttcatctagc ccatatacaa
     4081 tatcatatct gaaagcatct agtaacagtt cctcatactt cccttgcgaa attctgctat
     4141 tttctaaaag ttgttcagtc aaattaatat attatactaa taccatttcc tttttacttt
     4201 ctgacaaagg acgatataaa cttgtatcat agcctaatct tgaagctgtc tctataacac
     4261 taatatccat atttttaatt tcttctgcat caaggtatcc atcattcctc aatctatata
     4321 acatagcttt atgactgata ccataaaact gacccaattt tataatatct tctacttcaa
     4381 gatgagttct attggcattt tctctgattt cctcaaccat cctatacagt gaaatgggaa
     4441 aattaaaaaa taagaagcaa actgatccgc ttttctttca gtttcatctc cttcaccaat
     4501 caagataaga ctgactgaac tcttcttcac ctcatcataa taaagatgat acagttcatg
     4561 tgctaaagaa aatctttacc ttcctaatgg catgtctgaa ttgactgcaa tgagactgaa
     4621 atgagttcct ttataacaga ctccgctaat attctttccg agtccataaa ataccagcgt
     4681 caaattttct atcttttgta ccaatttaaa aatatctatc ggcgattcac catcagctcc
     4741 caactttttt ctaagatttg gagctttatt acttaaatcc attcgtgata ttcctttcac
     4801 ctttttccat tttggcaatc atgctttgat tcaaagacaa atactcagca atcttatctt
     4861 gagtaagatt tgaagatatt ctaagttctt ttattctttt tccaacatca catacattta
     4921 tcatatacat ttatcatatt catttatcat attcatacac ctctcataaa aagaatagca
     4981 cactcctgtc ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg
     5041 atgctgctta aaaatctaaa attgatgata ttaaacctat ttgatgaatt cctatcaaaa
     5101 atcgtatctt caacctcaaa acagtactta aagctatccg actcggttta cattgtcaaa
     5161 tttagatttt atttgagcat aactttctag tttgcttttt gatttttgtt taatatagta
     5221 gcaaaaattg aaggaaatat ctccacaaga aaacgcatac tattaagctt tttcaagacc
     5281 taataatatg cgctgttctg atttgaaaga cattccatta ttattttact gtaatcaagc
     5341 catctggctc tactgtgaat tctggcttgt ctgccagtgt tccgtctggt ttgaggtagt
     5401 accagcctgt tccgtccgct gactggataa aggcatttga taccatggcg ccttctttag
     5461 cgtctaagta gtaccaagtg tccttgtact tgacccagcc tgtcttcatg gcaccttctt
     5521 cgttgaaata gtaccactta tcagcgattt tcttccagcc tgtagccatt tcgcctgagt
     5581 tgtcgaacca gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca agcatatagc
     5641 ctgaactgtc aaagtagtac caagtgccat tgattttctc aaacttgtct tttggataag
     5701 agccgtctga gtgtacgtac cagtagccag tgtcattctt ctgccagcct gtttcaatcg
     5761 tcaagccgtt ctcaatatca tgcttaaact gctcacggct aatgccccat tttgccaagt
     5821 aagggtatgg atccacatgg tctgagtggt tgtttggttg gttattcgtg caatactcgt
     5881 gcgttttaat tccagctaaa ctccctgtat caagcgtttt cggcaaacct gcttcatctg
     5941 ctagattgcg taagagttcg atataaaggc ggtagtccgt catgaactct tctttagttg
     6001 aatggctttc aatcagttca accgctgcat aggtctcagc attccaaccg cccccaacgt
     6061 cccaggcacc attatcaaca ggtcctacct gcatgatgca accgttccca acaatgtgcg
     6121 agaaaaaacc taattctggg tctttccgcc agtgataatc cgcttcattc tgtacggttg
     6181 aatgcggatt cccagttgag tgtgcgtgta cttgcctata tggttgcacg ccgacttgag
     6241 gcaaatctgt tcttaattta ctcacattaa tttccatatt ctactcctta tcaattaaaa
     6301 caactcattt tttacaatcc aaaaccagaa actcctttat ttctacctta caaagaagac
     6361 aatcttagtc acgattaggc ttgtagatag aacctcaaaa cgcactattt tgacactgta
     6421 aataggactg acaaggtctg cattctatct acaataacac cccagactaa aaagcttttc
     6481 aaaagtatat ttttacagtc tctatatgtc cttttcataa atactatact ttattatatc
     6541 atataaaaga agtcaaaagt ctgttaaact attttcaaca ccaaactaaa gaagagaaca
     6601 caagtttttt cgatgttcac tagaggaaat ggattttatt cagtaaatcc aactaggatt
     6661 gcactttggt tgccaaaatt gcctttcctt cttttatcaa gggatgacgg aatagtgaga
     6721 agtacagttg aactgtcatg gcaacccaga taagaggttc acaaaggata acacccttat
     6781 atcctgccca aggaataatc aaaaccacaa aaacgatttt tccgattagt tcaataaagc
     6841 tagaaactag aggaaggatc ttctgcccca agccctgcaa gcaattgcga taaatcaaca
     6901 agaggctcaa aatgggataa aaggctgaac tgatttgcag atagagactt ccattttcta
     6961 tcaagtaacc atctgtcgaa ctagccaaga aggaaatcaa ggctgggctg gcaaaaaaga
     7021 ggaaaataca aacaaaaact gcccaggata tacttaaacg actgccgatt cgaagacctt
     7081 gagcaatgcg gtcaggtcgc ttagctccta gattctgaga agcaaaggtc gtcattgatg
     7141 cagaaatagc ggtcatagga agaagggcaa aggtcataat gcgtcgagct gccgtctggg
     7201 cactaataat cactgcacca aatgtattaa cagaagactg taaaatcaca ctgccgatag
     7261 atacaattga actcatcaag cccatagcca aaccttgctc caagagatcc gcgtacaagc
     7321 ttttgtccca tttgaaatgt ttaaactgtg gcaagagttc tggcacactt ttacgaatat
     7381 aataaaagca gagaaccgct gataaacctt gtgaaataat ggtagcaagt cctgcggatt
     7441 gaactcccag atgcaattgc gtaataaaat agagatccag aaccacatta accaaggcag
     7501 agaaaatcag aaatcccagg gctgctagac tgtcaccaat agaccgcaac aagcctgcaa
     7561 aaagattata agcaaagctg acacctacac aggtcacaat catagaaata tattgataag
     7621 attgaagaag aatttctgca ggagtatcta agtattgcaa gagaggatac aagccaagaa
     7681 agcccagtaa cataactaga atgctcaaaa gagcacctaa aatccaggtg gctgctactg
     7741 cttccttgat tttagtgaaa ttccgagccc cataataacg agcaatgaca atccccatgc
     7801 cattgccaac accaagtgta aaacctacaa tcaggtcaaa aatcgctgtc gtcgctccta
     7861 ctgcagccaa ggattcttga tcaagaaatc gtccaacaat caagacatca gcagtgttat
     7921 agagctgttg aaaaatattt gatagcaaga ttggaaaggt gaagcttaag agcgagggaa
     7981 gaatcggacc atgtatcagg tccactgttc gttttttatt cataaagcta ttatatcagc
     8041 tttccagagg agcgacaaga aacagcaaac ttatatatag cggaatgaaa taaggaaagt
     8101 caaatcgatt tttaacaatg ttttagaagt agatgtgtac tattctagtt tcgatctatt
     8161 atagttggtt gagtttggaa tagtacgctg tagctgctaa aac
//
LOCUS       DAVKMO010000066         8133 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVKMO010000066 DAVKMO010000000
VERSION     DAVKMO010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.066"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..244
                     /locus_tag="VW361_001861"
     CDS             <1..244
                     /locus_tag="VW361_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744847.1"
                     /translation="IIYDNEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQIVVI
                     NEFIACLNSRCVPSQYDRFFYKDRPYIFSRKSPIKG"
     gene            559..1536
                     /locus_tag="VW361_001862"
     CDS             559..1536
                     /locus_tag="VW361_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744848.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIVCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYIGIKHVSIRR"
     gene            1913..2287
                     /locus_tag="VW361_001863"
     CDS             1913..2287
                     /locus_tag="VW361_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU9744849.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            2495..3397
                     /locus_tag="VW361_001864"
     CDS             2495..3397
                     /locus_tag="VW361_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744850.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLITIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIRWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEAILGKI
                     VDSESTLLCIGLVELLLYEMSISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            3453..3806
                     /locus_tag="VW361_001865"
     CDS             3453..3806
                     /locus_tag="VW361_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU9744851.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGTYLSKRACQGICVALAMSPGT
                     FIALTGAAVLTKKLINYIKVGSFGGWLIGAAAGVLATAAGKIAYCIGYGVLNRGCDIN
                     GNPYPWDGFISATVR"
     gene            3803..4531
                     /locus_tag="VW361_001866"
     CDS             3803..4531
                     /locus_tag="VW361_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744852.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVANHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            5663..5902
                     /locus_tag="VW361_001867"
     CDS             5663..5902
                     /locus_tag="VW361_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744853.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            5887..6165
                     /locus_tag="VW361_001868"
     CDS             5887..6165
                     /locus_tag="VW361_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744854.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVASDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYVKVRKTDVKEMKWL"
     gene            6451..>8133
                     /locus_tag="VW361_001869"
     CDS             6451..>8133
                     /locus_tag="VW361_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEU9744855.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTFVRAEDAPVANQSQAEK
                     DYDAAMKKSEAAKKEYETAKKKAEDAQKKYDEDQKKTEEKAELVRKADEKRQKANLAV
                     QEAYVKFQEAQREFNESPSRKKSDAKKKLDDASAHIEEVKLKQKEADANFNKEQAKVI
                     PEASDLAVTKQKAEEAKKEAEVAKEKYDKAVQEVEVEKNKILEQDAENEKKIDVLQNK
                     VADLEKGIAPYQNKVAELNKEIARLQSDLKDAEENNVEDYIKEGLEQAIADKKAELAT
                     TQQNIDKTQKDLEDAELELEKVLATLDPEGKTQDELDKEAAEDANIEALQNKVADLEN
                     KVAELDKEVTRLQSDLKDAEENNVEDYVKEGLDKALTDKKVELNNTQKALDTAQKALD
                     TALNELGPDGDEEETPAPAPKPEQPAEQPKPAPAPQPAPAPKPEKTDDQQAEEDYARR
                     SEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAPKTGWKQENGMWYFYNTDGSMATGWLQ
                     NNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGA"
BASE COUNT         2868 a         1124 c         1500 g         2641 t
ORIGIN      
        1 aatcatttac gataatgaag cattaagaga tttgtcaaaa caatatttaa acaaaaatat
       61 ttcggaatta caagatggtt ctttcgaggg cggtatacaa gatgctgttg cctctaaaca
      121 aatagtagtt ataaatgaat ttatagcttg tttaaattcc agatgcgtgc catcccaata
      181 tgatagattt ttttataaag atagacctta tattttttcc agaaagagtc ctattaaggg
      241 gtgaaaattt gttacatttg gattaacaag tgtcctaggg attagaaata actctagtat
      301 agctagatat ttttgagtaa ctagaaatat cattaggcta cccatatgat tgccagaaaa
      361 gatggctgat gaatcttatt tatactgttg cagtaggcat tgtctaggat aaataagcta
      421 tcttgatggg ggagattgga ataattttag tagaaacatt aaaggattat ggacaagtag
      481 cgtaggatta ggtgatgcaa tgtgctaagt tggcttggtg ttagcagtag tattatttaa
      541 caatggaaag tagactaaat gaaaaataag cgttattttt ttgacacaat tttaataatt
      601 ttactgctta taagcacgat attttgtgtc agcccagtat ttataaaatt ggacatctta
      661 ggaactccct ctcatgccat cttaaccttt gtattggcga taccgttatt ctatattttg
      721 tctcaatgct tacatacttt gctattacta gtttcctcaa tcgtttgtaa attaagacca
      781 atttattttt attttatatt tgtgatcatt ataggagcta ggaaatacta tcgaattctc
      841 tttcaccaac taatgggatt tagtccagga atagcagtgt tttataagga gagtcaaaca
      901 actaagaatc tgtttaaatt ttactacttc ttgtacttta caacactaat ttcatactat
      961 tttttcttta cttttgtgta tgacaaatcg ttgcttttgc ctcttattcc attttctatt
     1021 atcatagcat tagtacaaaa actttataga attgagaatc aacaattatt tctgttaaaa
     1081 tcaaaggtac taacaatact ggaatctaag agggattgtg agtttaatct tcaggattat
     1141 catgaaattt ggaaattgca atcaaaatct gagttgccat gcgtggcttt atcttatatc
     1201 agtttgatca agccatatct ttcagagagc gtgcgtgaac aaattgattt attagaagtt
     1261 aagcgattta aaaaaataaa tcatccaata tcactttatg gtatgttgga tgttataaaa
     1321 ttaaatctat atttacggca ttataatgaa aaaaataaat atgaatcaat gttaaagaaa
     1381 attttagagg taagaccaga ctttgtttta atcgagcaga atattgatga tagtttaaat
     1441 agctcgcaac cattatcttt atctttagct atttcagaaa tccaactttt gcttgaagtg
     1501 tatataggga tcaaacatgt ttcaattagg agataaaact agaataacat ttgctattat
     1561 aggggcaagt tgcatattag tcagtatgta tcttatacct ctcattaaca cggataataa
     1621 attttgggaa atacttttat ttatattagg tgtattgcta attggaattg cgttactaag
     1681 tcaaaaaaaa taaattttga aatagtatta gtgagttcgc aatcatttat tgctagtggc
     1741 ttagaactgt taagtttcaa acaataattg attttaaacc ttaggtaacc tataaaaaca
     1801 aataaggtag agaaaggata tcttatctag gtagctaagt gataaaaaca cagtcgtcta
     1861 tcacttgtta ggaaactatc ctaactatgc ttaataaaaa aggagaaaat aaatggaact
     1921 cgtattacca aataattatg ttgttcttga gcaagaagag atgatgtatc ttgatggggg
     1981 attttctatt ccgagatggc ctgttgcaac agccattaat atagctttta atggtgtttt
     2041 aggtggagga gcaatcagtc tagttagaaa ttatattcgt aattatggtt tgcggcgagt
     2101 tacaagcgca attgctggag cagctgcaag atatgttggg gtacgagttg caaatagagt
     2161 ggcaggattt gcactgtctg ctattaatgg atttgcagct tggatgtcaa ttggcgatgc
     2221 tattacaaca atctgggcca ataatgatgt aaataggaga gacccaaatt taaacgcctt
     2281 gtggtaacta gatatgggta ttaaaatgga aaaaattttt gttattattt tttttgtatg
     2341 tctatttata tcatccataa cttttttagc ctatgatttt gttagcgaag aaataaaaaa
     2401 gttgattatt tggatgaatg tcgttttttt gattttaatc atagcaatga tgatttatcc
     2461 aaaattaaga aaatgataag gacactgtaa aattatgata cgtaaactaa ttgttttctt
     2521 actaatgctc cctctttttg tcttgtggct agagttgcat gtcctagtga ataacttact
     2581 attgaatcta gaatctcccc ttgattttgt gattagtatg agtcttgctt tttgtagttt
     2641 gattttatca aaaatagttt tagacatact atacgcattg aaagatttat acaagaaaga
     2701 aggtcttatt acgatttttc cctttatttt tataagaagg aaaaaagtga atgtgagatt
     2761 ctcgccctat ttttcattcc atcgtaaaag tttgtcgcct gatgatttaa gatctaggat
     2821 tagatggagt tttattcttg aaattgctat tatcctagta tttattttaa aaattccttt
     2881 tgcaatcatc atgcttacta caatattttt ctggactata atggatatca atcatctcgt
     2941 ttttaataag acggaatttc tttttaatca aaacaaatgg caaaaagaag attcgtttga
     3001 aagtgatttg acgaaaacgt taaaggataa aatacaaaag tcagagctaa gttattctga
     3061 cttaatgtct ctacagctgt atgatgcgat gaaccaatcc acctttttaa cggatagtga
     3121 actctttgag gctattctgg gaaaaattgt agattctgag agcactcttc tttgtatagg
     3181 acttgtagag ttgctgctat atgaaatgtc tattagtaac aataacaact ggtccaacaa
     3241 ggttgataaa attaggatac acctcatcag aatcaatcaa ttagattttt tctattatac
     3301 aagttggtta aggcaaaatt ttgatttctg tatgaataga gagtatcata aaatgaaatc
     3361 tcggaaatta ttactgagta ataaaaagat agtttaagtt cgtcctattt gtaaaacaaa
     3421 tgaaacaatt tcaactaagg aggagaaaac aaatggaact tgtattacca aataattatg
     3481 ttgtgattga tgaagaagaa atgatgtatc ttgatggggg aacttattta agcaagcgtg
     3541 cttgtcaagg aatttgcgta gctttagcta tgagtccagg aacttttata gcattgactg
     3601 gagctgcagt tttaaccaaa aaactaataa actatattaa ggttggaagc tttggaggct
     3661 ggcttattgg tgcagcagca ggtgtattgg ctacagcagc aggaaaaata gcttactgta
     3721 ttggatatgg tgttcttaat agaggttgtg atattaacgg gaacccttat ccttgggatg
     3781 gattcatatc tgcaacagta agatgagtaa tgtagataag attcgaaaaa tacacatcat
     3841 cgtgtgttgg gtgtatatat ttttatcatt cagggcgatt ataaatgata cggagtattt
     3901 tttgcttatt tttttagctt ttatctactc aatagtatca ctacctctat attctgtgaa
     3961 aaataaaata gtatctatct gtctagccat aaattcgatt ctgttaatga gtttccccat
     4021 tttaatcaat aagtttttcc cagaaagttt tttgacttat accgtattaa taagtgtttt
     4081 tattacagag ttgataattt ttcatttaat tgggaaagat tttgatatta aattgactaa
     4141 cgaatataag aaaattagtc agtttagaag caaggtgtct caatctcctt ggataaaata
     4201 tttagagatt tctagtttta tattaactat atttccatct attctttatg gtacagttgc
     4261 taatcatgta ctgactctta tctttttgat aaaaatttgt gtagatacca cgataaaatt
     4321 tttattcatc agattatttg acacaagtac tttaatgaag aggagaatat tttttctttt
     4381 cgcattggat gttatagctt acttattttt aggatatctt ttagtgattc aaaaagcagg
     4441 ctatttgttt tcggttttac ttcttttttc taatttttca gttccattta tcaaagaaaa
     4501 ggaatacgaa ttatttaaaa atagcaagta atagaaatat ggattaaatc ttagaacggc
     4561 ttaaaatcag atatgataaa gggaaatagt cttatctagg taactaagtg ctacaaacac
     4621 agtcgaggat cacttgttag gattacattt taatcatgct taataagaat ggagaattcc
     4681 tatggggatt gtattactct gaagtttcga ataccttagt tctcgtgatt ttgagctatt
     4741 ctagctttag aatccttcag aacgtaaaat tttaagcagt caaagactta gaatagcccg
     4801 aaaacattta ttttataaca attctaagat tagaattgct catatatatg tatttgagct
     4861 gctcgatagt taggacagct ctattctgag aaatctgacc tatcaatgct tcagaatagt
     4921 atttcgcaaa tggtttttat tgaagaggtg attgttttat gatagtctaa aataaaactg
     4981 atttatggag taaatggaga atcgtcacat gaaacatttt tttgcaggaa ttggtgagat
     5041 aaaacttgtt ggctacttat tgtatatatg tgtaggacta gcccctcttt ttcatatata
     5101 tgtcataggt tcggaactga gttttgtgaa aatagtgtta tctattttgg gagttatatt
     5161 tgtaagtatg ttaactattg ctcgaattta tcggactttt ctataaagaa tagtttggac
     5221 ttgaactgta tctaaaaaca gaggttggtc gattatcagc ctctttcttg tcgttgaaaa
     5281 gagtgagata tattgacttt tgaaaaaaat gtcataattg agttgggata aacctaaaag
     5341 taatatagta gattgaatct ggaatagtcc gttatgactg ttaaaatatt tctagaaatt
     5401 aatttgactt tcctaatcga tttgttcaca tcttgtttca atctactata ctttctcgtt
     5461 aaaccgttcg gcaattcatg gtgacatgga cacatagtag taagcacact atgtggcttg
     5521 gcagagctaa aaactgttcc cttgcgataa gcctaataag cacaacatag ggagttagag
     5581 aagccgactc taatcaacca ctttgggcaa tagtgagaac tgccccgtgc ttttttattt
     5641 tgagaaaata tggagtttgt cgttgaaatt acttgattgt attttggact atcaagaaag
     5701 attcaatgga aaaacatgtc aagtatcaac gaattataag tatttagaga ttttcaaagt
     5761 gaatttttgt ttgactgatt tacatcattt atttgactta tacaaaatca cacgagatta
     5821 tgctagtcaa acaaaacctg ctattcaagc tggtgttttt attttagaag attttagaaa
     5881 tatcctatgt acaatgatgt aatcgaaagg atatctttat atgagtttat cggtgatatt
     5941 ttctattcta aaataataag ttgttgcatc gtagctagcg atttatctaa aaatactatg
     6001 aaattggacg tcatattttt tgaggataaa aataaaagat ccgcagtttt aggtttacga
     6061 agagacaaaa gcggagtatt taaaccagtt actctacatt ttacaagcgc taagaaatat
     6121 gttaaagttc gtaaaacaga tgtgaaagaa atgaaatggc tataaagatt gtccgcaggc
     6181 ttaagcttgc gttttttgtt gtttaacgaa attaaaaaac aagctctctc atcggaaatg
     6241 tttttatagg aatgaaggaa gatgatgcta tgtttaaaaa gagaatcgaa aagggcaaaa
     6301 gtagtgtctt tatctttttg gagtagaagc ttatgatata gaaatttgta ataaaaatgt
     6361 aatataaaac atttgacaaa tatttacggg gggagtatac ttaatataag tatagtctaa
     6421 aaatgactat cagaaaagag gtaaatttag atgaataaga aaaaaatgat tttaacaagt
     6481 ctagccagcg tcgctatctt aggggctggt tttgttgcgt ctcagcctac ttttgtaaga
     6541 gcagaagacg ctcccgtagc taaccagtct caagctgaga aagactacga tgcagcaatg
     6601 aaaaaatctg aagctgctaa gaaagaatac gaaacggcta aaaagaaagc agaagacgct
     6661 cagaagaaat atgatgagga tcagaagaaa actgaggaga aagcagagct tgttcgaaaa
     6721 gcggatgaaa aacgtcaaaa agcgaatttg gcagttcaag aagcatatgt aaaattccaa
     6781 gaagcacaaa gagaatttaa cgaaagtcca agcagaaaaa aatctgatgc taaaaagaaa
     6841 ttagatgatg catcagctca tattgaagag gtaaaattaa aacaaaaaga ggcggatgcg
     6901 aattttaata aggaacaagc aaaagtaatt cccgaagcaa gtgacttagc tgttactaaa
     6961 caaaaagcgg aagaagctaa aaaagaagca gaagtagcta aggaaaaata tgataaggca
     7021 gttcaagagg tagaagtaga gaaaaataaa atacttgaac aagatgctga aaacgaaaag
     7081 aaaattgacg tacttcaaaa caaagtcgct gatttagaaa aaggaattgc tccttatcaa
     7141 aacaaagtcg ctgaattaaa taaagaaatt gctagacttc aaagcgattt aaaagatgct
     7201 gaagaaaata atgtagaaga ctatattaaa gaaggtttag agcaagctat cgctgataaa
     7261 aaagctgaat tagctacaac tcaacaaaac atagataaaa ctcaaaaaga tttagaggat
     7321 gctgaattag aacttgaaaa agtattagct acattagacc ctgaaggtaa aactcaagat
     7381 gaattagata aagaagctgc agaagatgct aatattgaag ctcttcaaaa caaagttgct
     7441 gatctagaaa acaaggttgc tgaattagat aaagaagtta ctagacttca aagcgattta
     7501 aaagatgctg aagaaaacaa tgtagaagac tacgttaaag aaggcttaga taaagctctt
     7561 actgataaaa aagttgaatt aaataatact caaaaagcat tagatactgc tcaaaaagca
     7621 ttagatactg ctcttaatga attaggtcct gacggtgatg aagaagaaac tccagctcca
     7681 gcaccaaaac cagagcaacc agctgaacaa ccaaaaccag cgccggctcc tcaaccagct
     7741 ccagcaccaa aaccagaaaa aacagatgat caacaagctg aagaagacta tgctcgtaga
     7801 tcagaagaag aatataaccg cttgccccaa cagcaaccgc caaaagcaga aaaaccagct
     7861 ccagcaccaa aaccagagca accagttcct gcaccaaaaa caggttggaa acaagaaaac
     7921 ggtatgtggt acttctacaa tactgatggt tcaatggcta caggttggct ccaaaacaac
     7981 ggttcatggt attacctcaa cagcaatggc gctatggcta caggttggct ccaatacaat
     8041 ggttcatggt attacctaaa cgctaacggc gctatggcta caggttgggc taaagtcaac
     8101 ggttcatggt actacctcaa cgctaatggt gct
//
LOCUS       DAVKMO010000067         8049 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVKMO010000067 DAVKMO010000000
VERSION     DAVKMO010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8049
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.067"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            144..725
                     /locus_tag="VW361_001870"
     CDS             144..725
                     /locus_tag="VW361_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9744856.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            722..1999
                     /locus_tag="VW361_001871"
     CDS             722..1999
                     /locus_tag="VW361_001871"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU9744857.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLIEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            2017..2679
                     /gene="deoC"
                     /locus_tag="VW361_001872"
     CDS             2017..2679
                     /gene="deoC"
                     /locus_tag="VW361_001872"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU9744858.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            2666..3055
                     /locus_tag="VW361_001873"
     CDS             2666..3055
                     /locus_tag="VW361_001873"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9744859.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGNVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            3146..4198
                     /locus_tag="VW361_001874"
     CDS             3146..4198
                     /locus_tag="VW361_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU9744860.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            4342..5877
                     /locus_tag="VW361_001875"
     CDS             4342..5877
                     /locus_tag="VW361_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744861.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            5870..6928
                     /locus_tag="VW361_001876"
     CDS             5870..6928
                     /locus_tag="VW361_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9744862.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            6931..7887
                     /locus_tag="VW361_001877"
     CDS             6931..7887
                     /locus_tag="VW361_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9744863.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            7972..>8049
                     /locus_tag="VW361_001878"
     CDS             7972..>8049
                     /locus_tag="VW361_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9744864.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSN"
BASE COUNT         2284 a         1445 c         1926 g         2394 t
ORIGIN      
        1 atggtttatt atttataagt gttgaaagag attgaagaaa atggcttcgt gactcgcttt
       61 cttcggtctt tttcgtttta ttatcaattt gtaaacgatt tacaatttga gtcaaattat
      121 ggtaaaatag tgtcatgagt aaaatgtatt atgcagaaaa tcctgacgct gctcacgaca
      181 ttcatgagtt gagagtagag ttgttgggac aaaaaatgac ctttttaacg gatgcgggtg
      241 tttttagcaa gaaaatagtt gactttggaa gtcaactatt gctcaagtgt cttgaggtca
      301 accaaggaga aactgtcctt gatgtaggct gtggttacgg acctttgggt ttgtccttag
      361 ctaaggctta tggagttcag gctactatgg ttgatatcaa cactcgtgcc ttggatttag
      421 ctcggagaaa tgctgaaaaa aataatgcaa aagcgacgat tttccagtcc aacatctatg
      481 aacaagttga aggacatttt gatcatgtca tttccaatcc tcctatccgt gcgggcaagc
      541 aagtcgttca tgaaatcatt gagaaaagta aagatttctt ggaaactggt ggggatttga
      601 caatcgtcat ccagaaaaaa caaggggctc caagtgctaa gtccaagatg gaggatgtgt
      661 ttggtaattg tgaaatcctt aaaaaagaca aaggatacta tatccttaga agtgtgaaag
      721 aatgagagca gttgatttaa tccaaaaaaa acgagacggt caagaactga cttcaagtga
      781 aattgaatgg ctgatagaag gctatgtatc aggaactgtt cctgattatc agatgtctgc
      841 ctttgctatg gctgtttatt ttaaaggaat gacgactcga gaaatctctg atttaacgat
      901 gaatatggtt aagactgggc aagagtttga cctgtcagcc attgatggtg tgaaagttga
      961 caagcattct actggtggtg tcggcgataa ggtaaccttg attttagctc ctcttgttgc
     1021 tagcttcggt gtgcctgtag caaaaatgag tggtcgtggt cttggccata caggcggaac
     1081 aattgataaa ttggagtcca ttaggggcta tcaagtagaa cgtagtcaag aggattttat
     1141 tcgtcaggtt caggatattg gagtatctgt cattgggcaa tcagaccagc tggtcaaagc
     1201 agataagctt ctctatgccc ttcgtgatgt gaccgcaact gtcgacacga ttcctttgat
     1261 tgcgagttcg gtgatgagca agaaaatcgc ggcaggggcg gatgctattt tgctagacgt
     1321 gactgtcggt gagggtgcct tcatgaagac ggttgatgag gcgcgtgagt tggctcaaac
     1381 tatggtagat cttggtaagg ttgttggacg gaagacagta gcagtgatta cggatatgag
     1441 ccagcctctg ggacgagcga ttggaaatcg tctggaaatc cttgaagcat tggagatttt
     1501 gcaaggtcaa ggacgtcagg atattaccca ctttatttgt gaattggctc aaattatgct
     1561 tggtttggca aatgttaaca agactgttga agaagttcgc caacatcttg agaatggtca
     1621 agcactggct aagtttgagg aaatggtgca agcccaaggt ggagacttgg aagacctcta
     1681 tcgtcctgta aatgtagctc atgtggtgga aatccctgct caggaaacgg gtgtcatttc
     1741 agctcttcca gctatggact ttggtcttta tgccatgagg ttgggtgctg gtcgtgcagt
     1801 taagtctgat gccttggact atgaaacagg aattgttttt gaaaagaaga ttggagactc
     1861 cgttcaaaag ggtgaaattg ttgcaaaagt atacacaaat gaaaaaattc cacctcaact
     1921 agttacagat ttccaaaaat gtgttaaaat aagtgatgaa gtgaaaaaaa tccgtgaaat
     1981 tgtagaaatc atctcctaaa tggagggaaa accgaaatga aattaaataa atatatagat
     2041 catacgcttt taaaacaaga tgcaaagaaa aaacaaattg atagtttgtt gtctgaggct
     2101 agagagtatg actttgccag tgtttgcgtt aatccgacct gggttgaaca tgctaaaaaa
     2161 ggacttgaag gcacagatgt taaggtttgc acagtagtag gtttcccttt gggagcaaca
     2221 acttcagccg tgaaagcatt tgagacaaaa gaagctatcc aaaatggtgc agatgagatt
     2281 gatatggtga tcaatgttgg agctctcaaa tcaggtaatt tagccttggt tgagtcagat
     2341 attcgcgcag tagtggaagc aagtggtgat aagttagtga aagtcattat tgaagcttgc
     2401 cttctgacag accaagaaaa aattgttgtt tgccaattgg cccaaaaagc tggggctgac
     2461 tttgttaaaa catctactgg tttttcaact ggtggtgcta cgatagcaga tgttacatta
     2521 atgcgtgaaa cagttggatc tgatatggga gtcaaggctg ctggtggagc tcgttcttat
     2581 gcagatgctc ttgcctttgt cgaagcaggt gcgacccgta tcggaacgtc agctggggta
     2641 gctattttaa aaggagaatt ggcagatggc gactactgag ttgattgaac tggcaattga
     2701 aaccagcaaa catgcctatg tcccctattc tcactttcct atcggagcag ttttagtagc
     2761 caaagacgga aatgtttaca cgggagtgaa tatcgaaaat gctagctatc ctttgaccaa
     2821 ttgcggtgag agaacagcta tttttaaggc tatatctgaa ggccaaagag aattttcaga
     2881 attgattgtc tatggtcaaa ctgaaaaacc gatttcacca tgtggtgctt gtcgccaagt
     2941 aatggtcgaa ttttttgaac aagatttaaa agtgacctta gtcgcaaaag ataaatcgac
     3001 ggtcgagatg acggtcgggg agttacttcc atattctttt acagacttaa attagtctga
     3061 gtcgctcttt gagtggcaag ggtctttgtg accaatcaat ccatacttgc aacatcgttg
     3121 cacatcttat ttaggaggtt cagtaatgaa caagaaacaa tggctaggtc ttggcctagt
     3181 tgcagtggca gcagttggac ttgctgcatg tggtaaccgc tcttctcgta acgcagcttc
     3241 atcttctgat gtgaagacaa aagcagcaat cgtcactgat actggtggtg ttgatgacaa
     3301 atcattcaac caatcagctt gggaaggttt gcaggcttgg ggtaaagaac acaatctttc
     3361 aaaagataac ggtttcactt acttccaatc aacaagtgaa gctgactacg ctaacaactt
     3421 gcaacaagcg gctggaagtt acaacctaat ctttggtgtt ggttttgccc ttcacaatgc
     3481 agttgaagaa gcagctaaag aacacactga cttgaactat gtcttgattg atgatgtgat
     3541 taaagaccaa aagaatgttg cgagcgtaac tttcgctgat aatgagtcag gttaccttgc
     3601 aggtgtggct gcagcaaaaa caactaagac aaaacaagtt ggttttgtag gtggtatcga
     3661 atctgaagtt atctctcgtt ttgaagcagg attcaaggct ggtgttgcgt cagtagaccc
     3721 atctatcaaa gtccaagttg actacgctgg ttcatttggt gatgcggcta aaggtaaaac
     3781 aattgcagcc gcacaatacg cagccggtgc agatattgtt taccaagtag ctggtggtac
     3841 aggtgcaggt gtctttgcag aggcaaaatc tctcaacgaa agccgtcctg aaaatgaaaa
     3901 agtttgggtt atcggtgttg accgtgacca agaagcagaa ggtaaataca cttctaaaga
     3961 tggcaaagaa tcaaactttg ttcttgtatc tactttgaaa caagttggta caactgtaaa
     4021 agatatttct aacaaggcag aaaaaggaga attccctggc ggtcaagtga tcgtttactc
     4081 attgaaggat aaaggggttg acttggcagt aacaaacctt tcagaagaag gtaaaaaagc
     4141 tgtcgaagat gcaaaagcta aaatccttga tggaagcgta aaagttcctg aaaaataatg
     4201 gatggaagtc atttcttagg aagcggccaa gggccgcttt tttaagagtt gagacaaagt
     4261 cattttgtct cagtaaagct tgctactaga caaactagca agttttattg aaataaaata
     4321 agactctgaa aggaagagca catggcacac gaaaatgtca ttgagatgcg tgatattacc
     4381 aaggtgtttg gtggatttgt tgctaacgac aaaatcaact tgcacctacg aaaaggtgaa
     4441 attcatgcac ttttaggaga aaatggggct ggtaagtcca cgctaatgaa catgttagca
     4501 gggcttcttg aaccaactag tggtgaaatc gcggtcaacg gtcaagttgt caatctcgac
     4561 tccccatcta aagcagctag cttgggaatc gggatggttc accagcactt tatgttggtt
     4621 gaagccttca cagtggctga aaacatcatt ttaggtagtg aattgactaa aaatggtgtg
     4681 ctagatatcg ctggagctag caaagaaatc aaggctcttt ctgaacgtta tggcttagct
     4741 gttgaccctt ctgccaaggt agcagatatc tcagttggag cccaacaacg tgtagaaatt
     4801 ttaaaaacac tttatcgggg ggctgatatc cttatctttg acgaaccaac ggctgttttg
     4861 actccatcag aaattgatga gttgatggct attatgaaaa atcttgtcaa agaaggaaaa
     4921 tcaattatct tgattaccca caaattggat gaaattcgag cagtttctga ccgtgttaca
     4981 gttatccgtc gtgggaaatc aattgaaacc gttgaaattg caggggctac caatgctgat
     5041 ttggcggaaa tgatggtagg acgttctgtt tcctttaaaa cagagaagca agcctctaaa
     5101 ccaaaagaag tggttttgtc tatcaaagat ttggtggtca atgaaaaccg tggtgttcca
     5161 gctgttaaaa atctgtcctt ggatgttcgt gctggagaga ttgttggtat tgcggggatt
     5221 gatggaaatg gtcagtctga actgattcaa gccattacag gtcttcgtaa ggttgaatct
     5281 ggtagcattg agctaaaagg agattcaatt gtaggcttgc acccacgtca gattacagaa
     5341 ctaagtgttg ggcacgttcc agaagaccgt caccgtgatg gcttgatttt ggaaatgatg
     5401 atatctgaaa atattgccct tcaaacctac tataaagaac cacatagtaa aaatggaatt
     5461 ttgaattatt caaatattac ttcttatgct aaaaagctga tggaagagtt tgatgttcgc
     5521 gctgccagtg aattagttcc tgcagctgca ctctcaggag gaaatcaaca aaaagcaatt
     5581 attgctcgtg aaattgatcg agatcctgat ctccttatcg ttagccagcc aactcgtggg
     5641 ttggatgtcg gtgccattga gtatatccac aaacgcttga ttgaagagcg tgataatggc
     5701 aaggctgtcc ttgttgtcag ctttgaattg gatgagattt taaacgtctc agaccgtatt
     5761 gccgttatcc acgatggtaa gattcaaggt attgtatcac cagaaacaac caataaacaa
     5821 gaacttggtg tcttgatggc tggtggaaac ttgggaaagg agaagagtga tgtctaaaaa
     5881 attacaacaa atttcggttc ccttgatttc tgtatttcta ggaattttac tcggagccat
     5941 tgtcatgtgg atcttcggtt atgatgctat ttggggctac gaagaattgt tctatacagc
     6001 ctttggcagt ctgcgtggga ttggagaaat cttccgtgct atgggtcctc tggtcttgat
     6061 tggtcttggt tttgcggttg ccagtcgagc tggtttcttt aacgtcggac ttcctggtca
     6121 ggctttggca ggttggattc tcagtggttg gtttgcgctg tcgcatccag atatgccccg
     6181 tcccttgatg attctagcaa ccatcgtgat tgccttgatt gctggtggga ttgtcggagc
     6241 gattccaggt attcttaggg cctatctagg gacgtcagag gttattgtaa ccatcatgat
     6301 gaactacatt gtcttgtatg tagggaatgc ctttatccat gctttcccta aagacttcat
     6361 gcaaagtaca gattcgacca ttcgtgttgg ggctaatgca acctatcaga caccttggtt
     6421 ggctgagttg actggtaact cacggatgaa tattggtatt ttctttgcca tcattgccgt
     6481 tgcagttatt tggttcatgc tcaagaaaac aactcttggt tttgaaatcc gtgcagttgg
     6541 tcttaatcca catgcttcag aatatgctgg tatttctgcc aagcggacta ttatcctatc
     6601 tatgattatt tcaggtgcct tggcaggtct tggtggagct gttgaaggtt tgggaacctt
     6661 ccagaacgtc tatgttcaag gttcgtcatt agctatcgga tttaacggaa tggcggttag
     6721 tttgcttgcg gccaactcac caattggtat actctttgca gccttcctat ttggcgttct
     6781 ccaagttggg gctcctggta tgaatgcggc gcaggtacca tctgagcttg tcagcattgt
     6841 aacagcgtct attatcttct ttgtcagtgt tcattacctt atcgaacgct ttgtcaaacc
     6901 gaaaaaacaa gttaaaggag gtaagtaaag atgtctatta taaccttgct ccccctcttg
     6961 gtgtcttcta tgctgattta ctcagcacct ctcatcttta caagtatcgg tggtgttttc
     7021 tctgaacgtg gtggtgtggt aaacgttggc cttgaaggaa ttatggttat gggtgccttt
     7081 tctggagttg tctttaacct tgaatttgca gaacaatttg gagcagcaac tccatggcta
     7141 tccttgcttg tagcaggatt ggttggtagt gttttctcta tcatccacgc agcagcgacg
     7201 gttcatttcc gtgcagacca tgttgtcagc ggtacggtat tgaacttgat ggcgcctgcc
     7261 ttggctgttt tcttagttaa agttctttat aacaaaggac aaaccgacaa cctaagtcaa
     7321 acttttggac gctttgattt cccagtcttg gcaaatatcc cagtgattgg tgatatcttc
     7381 ttcaagtcaa ctagtctact tggttatctg gcgattgcct tctcattcct tgcttggttt
     7441 attctcttta agactcaatt tggtcttcgt ctccgctctg tcggtgaaca tcctcaagca
     7501 gcggatacct tgggaatcaa cgtctacaag atgagatatt tagggattat tatttcaggt
     7561 tttctaggtg gaattggcgg agcgatttat gcgcaatcaa tctcagttaa cttttcagtg
     7621 acaactattg ttggacctgg atttatcgcc cttgctgcga tgatctttgg gaaatggaat
     7681 ccaatcggtg ctatgctttc tagtctcttc tttggacttt cacaaagttt ggctgttatc
     7741 ggttctcaat tgccgttcct acaaggagtg ccagcggttt atcttcaaat tgcaccttat
     7801 gttttgacaa ttcttgtctt agcagccttc tttggaaaag cagtcgcacc aaaagcagat
     7861 ggtatcaact acatcaaatc aaaataagca tacaaaaaaa cgtcagtcca atgactgaac
     7921 tgccccccaa aagttagaca gaaaaaatct aacttttggg gtgtttttat tatgaaacta
     7981 acttatgatg ataaagttca gatctatgaa cttagaaaac aaggatatag cttagagaag
     8041 ctttcaaat
//
LOCUS       DAVKMO010000068         7963 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVKMO010000068 DAVKMO010000000
VERSION     DAVKMO010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.068"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..383)
                     /locus_tag="VW361_001879"
     CDS             complement(<1..383)
                     /locus_tag="VW361_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744865.1"
                     /translation="MGGAYLSKSACQGICAALAMSSGTFIALTGAAVLTKKLINYIKV
                     GGLGGWLIGAAAGVLALIFLIKICVDTTIKVLLNRIFKASKVMKRRIFSLFVLDLMVY
                     IFLGYVLVIQKDVYLFSILIIFSNFS"
     gene            complement(422..760)
                     /locus_tag="VW361_001880"
     CDS             complement(422..760)
                     /locus_tag="VW361_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HEU9744866.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            1353..1673
                     /locus_tag="VW361_001881"
     CDS             1353..1673
                     /locus_tag="VW361_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9744867.1"
                     /translation="MQRLEVYKNYQRLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(1963..2433)
                     /locus_tag="VW361_001882"
     CDS             complement(1963..2433)
                     /locus_tag="VW361_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU9744868.1"
                     /translation="MRMPLKRPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVAVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(2399..3205)
                     /locus_tag="VW361_001883"
     CDS             complement(2399..3205)
                     /locus_tag="VW361_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9744869.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(3412..4053)
                     /locus_tag="VW361_001884"
     CDS             complement(3412..4053)
                     /locus_tag="VW361_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744870.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(4050..6158)
                     /locus_tag="VW361_001885"
     CDS             complement(4050..6158)
                     /locus_tag="VW361_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9744871.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKNLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(6210..6461)
                     /locus_tag="VW361_001886"
     CDS             complement(6210..6461)
                     /locus_tag="VW361_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU9744872.1"
                     /translation="MVCSILASTSVLAVWVDGGQWNYGVGWSGNFGYSDYLHSTRSHT
                     ATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            6913..7233
                     /locus_tag="VW361_001887"
     CDS             6913..7233
                     /locus_tag="VW361_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9744873.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            complement(7284..7871)
                     /locus_tag="VW361_001888"
     CDS             complement(7284..7871)
                     /locus_tag="VW361_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9744874.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNG
                     DYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY"
BASE COUNT         2500 a         1717 c         1244 g         2502 t
ORIGIN      
        1 gaaaaattag aaaaaattat cagaattgaa aacagatata cgtctttttg tatcactaaa
       61 acataaccta aaaatatata gaccatcaaa tctagtacaa aaagagaaaa tatcctcctt
      121 ttcattacct tacttgcctt aaagattctg tttaatagaa cctttatcgt agtatctaca
      181 caaattttta tcaaaaagat aagagccaat acacctgctg ctgcaccaat aagccaacct
      241 ccaaggcctc caaccttaat atagtttatt agtttttttg ttaaaactgc agctccagtc
      301 aatgctataa aagttcctga gctcatagct aaagctgcgc aaattccttg acaagcactc
      361 ttgcttaaat aagccccccc catcaagata catcatctcc tcttgctcaa gagcaacata
      421 attatttggt aatacgagtt ccatttattt tctcctttat actatgtaat accacaaaat
      481 gattttgacc taaatcattc ttaacttgaa gaatcgcagg aaatgttaat tttggagtca
      541 aatcttccag tgccactcga acagctttta ctgtaaaatt caacttattc agacctgaaa
      601 caataccact gacagtcgtt ccatacatgt ctgtaccaat aatttcccga atcttcatga
      661 ttgatagttc ctttttgtaa gataaaagaa ctgttgaaac aactgccgca gcacaatctg
      721 actgatcatg ttgcatcgta caaggatatt tttttaacat agaaatactc aattctttag
      781 aattaatcta acttttcttt gatgtcaccc aaacctcaat cactgcccag tagttcttga
      841 atcagtttat tttcaatcgt atcattcttt gttcttgata tctttccaag cattgtagta
      901 cagcagattt ttgtccaagg actaagcctc ctttaacaac tcaagctccc ttacattata
      961 tcgaccagcc ccatggaaag attatggcca gactaatcaa tgatatcata catactagaa
     1021 tacaaaatat ttttttattc atactttttc tcctatcttt attttctacc tacatcatac
     1081 ctcttattaa gctcatttta aaattacgtt aacttttttc acgaaaagga gaaaattatg
     1141 cgttatgatt atggatagcg ctttcaaatt tttaaactcc tatcccgtcc ttttatctat
     1201 ataataagca taagcgaaaa tataataact gtcaagtatc tgaagtgaat tttataaaaa
     1261 aattacaagc caaatttgta aagtttacac taagccgcta gggcaatcgt ctatcagaat
     1321 gtccgtttat ttgtcaataa tccgagaaaa tcttgcaacg cttagaagtc tataaaaact
     1381 atcaacgttt atatgacttg cgaatagcaa tcctgctcaa cctttccaca ctctatctat
     1441 acaatcaaga taaaaacatg tgtaagcaaa tctgctacac tttactggag gacgccaaga
     1501 ataagaaaag ctacgatagg ctggctatct gctatgttcg tattgggatt tgtagggata
     1561 atgctaaact tatccaaaaa ggtttctcac tcctagagct gaccgaggaa acttctatgc
     1621 tgtctcatct caaaaaagaa gtagagaccc attatcaacc aaagaaatta taaaaaaagt
     1681 cgagggattt cctcgactct ttacatatta tttgttcgtt agttcttaat atcagccatt
     1741 gttaaaccag aagtttttag ctctgccaag ccacatagtg tgtttacttc tatgtgtcca
     1801 tgtcaccatg aatcgccgaa cgatttaacg agaaagtatg acttttacgt ttatcccaac
     1861 tcaattatga catttttttc aaaagtcaat atatctcact ttttcaacga caagaaagag
     1921 gctgataatc taccaacctc ttattctgaa cccatcactc catcactttt tagcttcatt
     1981 cgctttctta gcgactgcaa tctggtattc gacttggtca ttccccttac ctgtacaacc
     2041 atgagcaatt gtagtcgctc ctgtctgatg cgctatttca accaattttt tagaaataag
     2101 agggcggctc aaggcagata ccaaggggta cttttgttca tagtaggcat gtgactggag
     2161 agctactagc acataatctg tagcaaattc gtccttaaca tcaatgacat aagattcgac
     2221 tgccccaacc ttaagagcct tatcatggat gaaatctaag tctttccctt cacccacatc
     2281 catacaaact gcaacaacat catagtcttt cttcagccag gtaatagcaa ctgatgtgtc
     2341 taaaccgcca gaataggcca aaattacttt ttctttactc atgttctttt ccttctttct
     2401 atttttcaat ggacgcttta aaggcatcct caatgagttt gtctaattcc ccagactcct
     2461 tcaacttttg aatggtttta tcgactgcct ctttcaattc cttgctatct tttttcatgg
     2521 ctaccgcata ggaatcatct tgctcttttt caaaattgag gtctgcgatt gctaaatcag
     2581 gattattttc cacaaatccc ttggcaacgg gttcttcaaa aataacggca tccacttgcc
     2641 ctgattttaa atctgtgatt aaattcccat ttttaggcag agatacgagg gaagaatttt
     2701 gtagcaaatc tttcgccatc gtctcttgaa tcgaaccttt ctgcgctccg acctttttct
     2761 gcgccaaatc gttgacagac tgataagtgg ctaaatcaga ttttttgaca atgagtttat
     2821 tttttgcagt atagtaggga gttgaaaaat caaacacctt gctccgttca tctgtcttag
     2881 aaacacctga tatggcaagg tcggcttttc ctgattgaac actagccagt acattatcaa
     2941 aactcatggg agatagttcc aattcgacac ctagttctgt tgcgatagcc ttggctaatt
     3001 cgatatctga acccacaatc tgatttttcc catcaaccac tttttgatat tcaaatggag
     3061 caaaatctgg attgagggct acaaccaatt ttcctttgga cttgatggct tcaattccag
     3121 ccgattgatt gttactacaa gcaaatagta gggggagcat cactaaacca aacatcgtca
     3181 tcaacacctt cttcatctta ttcataacaa agcctccttt atgtttattc ttttttattg
     3241 tataaataat actcctatac tcatcctttg tcaagcctaa attgaaaaaa ttttcaattt
     3301 gaaacaaaaa aaacctagaa atactacata aaatgtcatt cctaggcgta tttatgctat
     3361 ttttctctgg aaaacatgag tattcagcca gtcaaaagga gctgaatgaa ctcattttcc
     3421 ctcgcccaat tcaatgacac gatgacattg ttgggctaca taagcatcgt gggtcacaat
     3481 aatgactgtt ttcccttctc gattcatctc taagagaaac ttcaagacca aatctctatt
     3541 ttcaggatcc agcgaacctg taggttcatc ggctaaaatc agctggctgg gttttaagat
     3601 ggctctagca actgcaattc gttgttgttc gcccccagac aactcggaga ccctttgatg
     3661 caaagtagct gacaaaccta ctctctctaa aatctcttcc acctttttga gcttgtcttt
     3721 cttaggcaat ttcacatatt tcagcgccag catgagattg tactcgaccg tttcatcatc
     3781 aatcagggca aaattttgaa acagataaga gatatgttca cggattattg tttgcgactt
     3841 agcagaatta accgctagat ttgtctgacc aaaaatctca taccgtccgc tataatcacc
     3901 atctatcaaa cccaataaat ttaacaaggt cgacttccca ctaccactct taccaacaat
     3961 agctaccaaa tccccctgat caatcctgag agataagtta tccaaaatca cttttccccc
     4021 aatggttttg gtaatatttt tcaactcaat cataagatgc cccctttcaa taactctact
     4081 agacttcttt tctccatcct agaagctaag cctagcacaa atagtatatc cagacatgta
     4141 aaacctgcaa acagtagaag tggtaagaac gcatgggcaa agaaaatcaa gactagaaga
     4201 gggaaactat agcccagcaa gagcagaacg aggagaggac ggtagcgatc gaccagtttc
     4261 caccccataa acttcttggt aatgatatcc ctgcgcttca ataagaaagt tgttactagt
     4321 aagaagtagg aaatcatcat gctaaggaga ccaaacaaag caaagagtag gttaaaattc
     4381 cgaacagcat ctctataaga atccactttc tcttgttgaa tggcttgaat agatgaaaat
     4441 tttaaataat ttccatctga caatttctca actaactctg taatctcttt ttgatgttga
     4501 accgtatttt caattttaat cggattattt aagccagttg ttgacaggga ggctttctca
     4561 tcccacatca tatcagaatc attgaccaag ctaataattg gattggagag attttccttt
     4621 cgcttatcac tatatgggaa aaatgaccaa tctccttcat aataggcaat ctcgacatcc
     4681 atctcctcta tcgttcgttt ttgctgctct tcatacttca tcgaatgaaa ggcaattaac
     4741 ttccccaaga gctgattttt atcttcttca cctttcgtac ttgctggcat caaaataact
     4801 tttttaatac cggtatctgg tagcttgaat cccttgctct ttagaaaatt gcgattggca
     4861 tagtaaacat ccaccgtatc tgttaactga tattgctgaa tctgttctga ttggacaaaa
     4921 ttttttacag gaagactgct actctgcaca tagcccgcct gcgttttttc taccaaatcc
     4981 tgataaaatc gatagaaata atctgtagat ttccctgacc ctgctagctc ttcttgccac
     5041 agattatcat tgagtttgaa ggtttctaag gtcaggtaat taccttgact tacccactgt
     5101 tgctgataag caagttcttt gttttcttgt tctaaacttc tgcccacccc aatcagtaag
     5161 gccgtcagta aaatagttgt ccctattttc atcacataat tgaagataag accaaatttg
     5221 aaagatgaaa aacctttcag cagagagctg attgtcattt tttggattaa gaggtaagtc
     5281 aaccaactga taaagagata aagctgcaac agcaaaaaat gagacaacca cagcatagga
     5341 aacaaatttt ttggcttata atcaagcaag aaaaacacgc ctagattgat cacaagagcc
     5401 ccacctagga ggaggtaaag gttgcctttt acaacatcag ctaaaacagc cctatcttga
     5461 aaaccaagta atttttgtac cccaactctt ttcatctcca tcatcggttg atacactgtc
     5521 actaacacaa gaagcaaaat agccaagaca aaaacaatgg cagataaaag caaatctcga
     5581 tttatgactt ccactgcact tttgtaggtc ggctctagca aggtagcctg gtctatcttg
     5641 aaaaaatcgc tccatttctg tacaatccta tccttgtcca tctcttgtgt agaagttatc
     5701 gtatagcgac catttaaact acgagatgta tccttgatat aggtttgaaa agtcataagc
     5761 tgaataggtt tggcttttag aaaggtcgga atcgtaccaa gtttattgga aatttcttta
     5821 ttactataga ctccttcacc atctgtggta aaatcaagag aagaaatccc aaactcttgg
     5881 taggggaagg tatctttatc aaaaacacca gacttgacca cctcatcacc actgtctgtt
     5941 ttgatgatgg agactttata ctcctttgat acatcctcaa aaaatcgaag aacagacgct
     6001 gcaggttcgt taatatcttt caaatacaaa tccaaagaat ctacagtctt tcccatttct
     6061 tgaatccgaa ccacttctcg tgtatagttt acattaaaaa caaaaaaagt ggtacacaga
     6121 agcaggagta acatacagaa attactgatt tttttcataa aagtgcctcc actacagttt
     6181 tccctctcca aataggagag ggaagaattt tactcaaatc catagaaata ttccattcct
     6241 gttggcggaa tcttggtgag ggaagctcta gcccatgcct caggttttgc ataatcctta
     6301 gaggttctac ccccatgtct aacagttgct gtatgagagc gagtagaatg taaataatca
     6361 gaataaccaa aatttcctga ccatcctact ccatagttcc attgaccacc atcaacccat
     6421 actgccaaaa cacttgtaga agcaagtata ctacatacca ttaaagatgc aacaccaatt
     6481 ttctcatgat ttatttctcc tattatcgag agctattccg tagaaacagc tatagtaatt
     6541 tgtcaacaag tatcgtagtc cattggactc accttccttc tatctcattt catttttaaa
     6601 caacgaactt actcttaact agaagaatag ttctcttctg tatcaggtct ttgaacaacc
     6661 agagtagtat taatcacact ctaactatta ctcaagaatc agcccaataa acaatatgga
     6721 tagcgctttc aaatttttaa actcttatcc catcctttta tctatataat aagtgaaaat
     6781 ataataactg tcaagtaatc gaagtgaatt ttataaaaaa aattacaagc caaatttgca
     6841 aagtttacaa taagccgcta gggcaatcgt ctatcagaat gtccgtttat ttgtcaataa
     6901 tccgagaaaa tcttgcaacg cttagaagtc tataaaaact atcaacattt atatgacttg
     6961 cgaatagcaa tcctgctcaa cctttccaca ctctatctat acaatcaaga taaaaacatg
     7021 tgtaagcaaa tctgctacac tttactagag gacgccaaga ataagaaaag ctacgatagg
     7081 ctggctatct gctatgtccg tattgggatt tgtacagacg attctaaact tatccaaaaa
     7141 ggtttctcac tcctagagct gaccgaggaa acttctatgc tgtctcatct caaaaaagaa
     7201 gtagagatct attaccaagc gaaggaaaga taaaaaagcc gagggagctc ctcgaccttt
     7261 tcatattatt tgttcgttag ttcttaatac cagccattgt taagccagaa gtttttagca
     7321 gcagtccatg aaccgtaacg tcctgcaacg taggcatctg ctacacgttc ttggttttca
     7381 gctgagtagt caccgttcag gtatgaatct gttaattggt aacgtccgat ataacgtcca
     7441 tttgtagctg tatagctacc acctgattct ttttgagcga tccattcttt ggcttctgct
     7501 tcagatccgc ttacagttga aacaactgtt tcacttacta ctggagtttc tgctactgga
     7561 gctgaaacag tttcatcttg agcggctggt gccgcataag tagctggcgc tggtgttgca
     7621 acaggcgcta cagggccatc gataaccaac tcttgaccaa cataaatcaa atgaatgtta
     7681 tcaatgtggt tgttttctgc caatttttca actgttgtgt tgtgagtttc agcgatttct
     7741 gaaagtgtat caccttcttt aacagtgtaa gttgatgatt cttgagcaga tacaaatgat
     7801 ggagcaaata ctgcaaacaa ggcagctact cctgcaagag ttgctttaat ctttttagtt
     7861 attgatttca tattcgaaaa ttctccttct ttctatagtt ctatcatacc ctttaaatat
     7921 taccgtttct tgacactttt atgtagaaat attacaaaat tat
//
LOCUS       DAVKMO010000069         7157 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVKMO010000069 DAVKMO010000000
VERSION     DAVKMO010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7157
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.069"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(1..604)
                     /locus_tag="VW361_001889"
                     /pseudo
     CDS             complement(1..604)
                     /locus_tag="VW361_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            663..845
                     /locus_tag="VW361_001890"
     CDS             663..845
                     /locus_tag="VW361_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU9744875.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIASELVAGLR"
     gene            1146..1985
                     /locus_tag="VW361_001891"
     CDS             1146..1985
                     /locus_tag="VW361_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU9744876.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            2003..3841
                     /locus_tag="VW361_001892"
     CDS             2003..3841
                     /locus_tag="VW361_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9744877.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTLAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3854..5269
                     /locus_tag="VW361_001893"
     CDS             3854..5269
                     /locus_tag="VW361_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9744878.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLKRYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGSGTLNRY
                     KKMSFTWYKEVIESNGESLFK"
     gene            5567..6913
                     /locus_tag="VW361_001894"
     CDS             5567..6913
                     /locus_tag="VW361_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEU9744879.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     QISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLKLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT         2304 a         1116 c         1366 g         2371 t
ORIGIN      
        1 ggtttgtcta gctgtttcaa gtgatagtag taggtcgaac gagctagttt aatggctttt
       61 agaagaagat ctaacgaaaa ctcagtcatt aattcttgaa caatttctgt ctttcttctt
      121 tctctttttc ctccttcaat cggagttctc ttaacttttt taggatggca ttctccgctc
      181 tcaggtactc attttctgat tgaagacgtt ctaattctgt cctctcttca ggtctcgttt
      241 ttggattacg tcccatttta ggtactctcc ctcttgtttt ctcaacaata gtatacccgt
      301 ttttcctgta ttgtgctagc cagttaagaa gtatcgtacg acttgggagg cagtattcaa
      361 gagaaactct atctttagtc cagccttcat gtcagacttt atgaatcatt tcttgtttta
      421 aatcaggaga atagtaacga ttttttcctt ttttgacgaa ctctattccg taacgatcaa
      481 tcaatttaat catgtaccta agattagaat tgtttatccc aaatttattt gaaagcttct
      541 ctaagctata tccttgtttt ctaagttcat agatctgaac tttatcatca taagttagtt
      601 tcatactaaa acaccccaaa agttagattt tttctgtcta acttttgggg tgcagttcac
      661 agttgaagag ccagaaaatt aaagtgtctt ttactcaatc aaaaatagta acgcctattc
      721 ttttggtgaa taagactatt gtttggtatg gtgcaatgcc attattaggg aaggtagatg
      781 agatgaccat attacgtttg gaatcagcta gtatagcttc tgaactagtg gcaggtttac
      841 gatagagaaa atttttaaaa atttctatgt atgattttca tttctttagt gagactgttg
      901 ccattatcac attcgaatca cacaaaataa aaaaattttt ataagtactt gacaaataga
      961 ttgaaatatc ataaaataaa aacggttaca gagttattaa ttatttaagc ttcatgtcac
     1021 cattaaaaat tgaaataaaa ggatgttatc actaatacaa gtgagcagga acctatttaa
     1081 tcacatcaga agaagtttct tgatgttttt taagtaggtt ccttttattt taaaagggaa
     1141 attttatgat cataaaacga atactaaacc acaatgccgt aattgcgcaa agtaaaaaag
     1201 atatcgatat tcttcttttt ggaaggggaa tagcttttgg aagaaaaatt ggagataaag
     1261 taaatccaat tgatattgag aaaagttttt ttctcaaaaa tagagataat atgacccgtt
     1321 ttacagagat gtttattaac gttcctttgg agttggtgta catcaccgaa aaaataatta
     1381 atctaggtaa aataacatta ggtaataatt ttgatgagat tatctatata aatctaacgg
     1441 atcatatttc ttcgagtata gaacgttata aagaaggagt tattatttcg aatcccctac
     1501 gctgggaaat atcgaaatat tataaagaag aatttgagct tgggaaaagg gctttacaaa
     1561 taataaaaaa agagttaggt attgaacttc caattgacga agctgcattc atagcgctac
     1621 attttgttaa tgctaattta gaaaataatt ttcaagagtc gtataaaatc actgaaataa
     1681 ttatgggaat tgagaaaatc attcaagatt tctattgtac tgagtttaac caagattcta
     1741 ttgattatta tagattcata actcatataa aattatttgc ccatcgcttg gttgaaaata
     1801 caacttattg tgacgatgat gatgaagact tgttagcatt aatgaaaaat aaatatccta
     1861 gagaatatga atgtggtgaa caggtggcaa tgtttataca aactgagtac aattatttgc
     1921 tgacttctag tgaattagtt tatttgatgg ctcatattcg tcgcttaaca aaaaatttag
     1981 attaatagaa taggagaata ccatgagtta taaagatacg gtacaaaaaa tcctcgatgt
     2041 aattggaggt gaaaaaaatg tcaatagagt tacccattgt gtaacacgtt taagattaga
     2101 attaaaagat gaaaatttag tcaatgatga tgatgtgaag aagataccag gtgtaatagg
     2161 tattatgaaa aagaatggac aatatcaaat tatacttggt aatgatgtag ctaattatta
     2221 taaagaattc gttaaacttg gcaattttga atccgattca gttgttcaag ggcacaaagg
     2281 gaatatttta gaaagaatca ttgagtatat cgctggttcc atgactccaa tcattccagc
     2341 aatgttaggg ggaggtatgt tgaaagtctt ggtaatcatt ttaccaatgc ttggtatatt
     2401 gcaatcagat tctcagacta ttgctttttt gacatttttt ggggatgctc catattattt
     2461 cttaccgctg ttattagctt attctgcatc acaaaaatta aaagtaacat ctacattagc
     2521 tatgtctgta gcaggtgtac ttctccatcc aaattttgtt caaatggtgc aatcagggaa
     2581 tcctcttagt ttatttggtg cacctgtgac accagctagt tatggttcat cagtcgttcc
     2641 aattcttatt atggtttggt tgatgaaata tattgaaaaa ataattgcta aattaacact
     2701 agctattact aagagttttt tgcaacctac gctagtatta ttagtatcaa gctgtattgc
     2761 cttagttgta gtcggaccta ttggagtaat tgttggtgaa ggattatcaa atctagttgg
     2821 gcaaatgtat ggtgtagctg gatggcttac attagctatt cttggtgcta ttatgccatt
     2881 tattgttatg actggaatgc attgggcttt tgcacctatt tttttggcgg catctattgc
     2941 tactccagac gtattaattc ttccagcaat gttagggtca aacttagctc aaggggctgc
     3001 ttcgatggct gttgcattaa agagtaaaaa taataataca aaacaaattg cttttgcagc
     3061 aggtttctca gccttacttg cagggattac cgaacctgca ttatatggtg tgactttaaa
     3121 atataaaaaa ccgctttatg cagctatgat tggtggtgga ttagcgggat tatttgcagg
     3181 tcttactagt gttaaagcat atctatttgc tgtcccatct ttgatagcgt tgcctcaatt
     3241 tatttattct gatgtgccat caaatattgt aaatgcttta attgtggcgg tcatttcggt
     3301 tgttattacc tttgtattag cttatatatt tggaatcgat gaagaagaga gttctagcaa
     3361 tttagaagtt gaagctggag tttcaaataa aaaaatgata ttttctccta tatcaggaga
     3421 aatcattccg ttaagcgatg tccaggataa aacattttca gataaactaa ttggagacgg
     3481 agtagcgatt atcccaagtg aaggtaaggt ttatgcacca tttgatggga aaattacaaa
     3541 tatttttccg actaagcacg caattggatt gaagagtgat gagggtgttg agttactaat
     3601 tcatattgga ttagatactg ttgagctaaa aggtcaaggt tttattagtc atgtagaaga
     3661 aggagacaga gttttcaaaa atcagttgat ttttgaaatg gacttgaatt taatcaagac
     3721 taaaggctac gaaacagtta caccagtaat tgtaacgaat accaatgatt ttctagatgt
     3781 attagtatta cctaataatc agacaatcga gcattctaag gaattactgg taatattata
     3841 atggaggaaa gttatgacca tttttccaga tgattttctt tggggtggag ctgttgcagc
     3901 taatcaagta gagggagcat ataatgaaga tggtaagggc ttatcagttc aggatgtgtt
     3961 acccaaaggt ggattaggag aagcaacaga aaatcctaca gaagataact taaaattgat
     4021 aggtattgat ttttatcata aatataagga agatatatcc ttgttttctg aaatgggctt
     4081 taatgttttt cgtacttcta ttgcatggag tagaattttt ccaaaaggag atgaggaaga
     4141 acctaacgaa gctggtttga aatattatga tgaattattt gatgaactac atgctcacgg
     4201 gatagaacca cttgtaactc tttcacacta tgagactcca ttatatttag caagaaaata
     4261 tcatggatgg attgatagga gaatgattca tttttatgaa aaatttgctc gaacagtttt
     4321 aaaaaggtat aaagataaag ttaaatattg gcttacattt aacgaagtaa actctgtttt
     4381 ggaattaccg tttactagtg gaggaataga tatacctaag gagaatcttt cgaaacaaga
     4441 attatatcaa gctatacatc atgaattagt cgcctcgagt ttggttacaa aaattgctcg
     4501 tgagattaat tcagagttta aggtggggtg tatggtatta gctatgccag cttatccaat
     4561 gactccaaat ccaaaagatg tatgggcgac tcatgagtat gagaatctaa attatctatt
     4621 ttcagatgtg catgttagag gttattatcc gaattatgca aaaagatatt ttaaggaaca
     4681 tgacattaac atagagtttg cagctgaaga tgcagagtta ttaaaaaatt ataccgtaga
     4741 ttttttatcc tttagctatt acatgagtgt gactcaatct gctcttccaa cacagtataa
     4801 ttcaggagaa gggaatatta ttggtggctt agtaaatcct tatttagagt cttctgagtg
     4861 gggatggcaa attgatccaa ttggactacg tataatttta aatagatatt atgaccgtta
     4921 tcaaattcca ttatttatag tggaaaacgg attaggtgct aaagatcaac taataaaaga
     4981 tgaatttaat aacttaacag tccaagatga ttatagaatt cagtatatga aagaacattt
     5041 attgcaagta gctgaagctc tacaagatgg tgtggaaatt atgggctata cgtcttgggg
     5101 atgtattgac tgtgtttcta tgtccactgc acaactttct aaaaggtacg gtctcattta
     5161 tgttgatcga aacgatgatg gaagtggtac attaaatcga tataagaaaa tgtcttttac
     5221 ttggtataaa gaagtgattg aatcaaatgg agaatcctta ttcaaatagt tttttattga
     5281 tgactagcta ttatcacggt taaggcagca tttcattaaa tatggaataa agaagtttgg
     5341 aagacattaa attctaaact tctttatttt atagggggat taattaattt aattttgtta
     5401 cccccaatta ttcaccccta atctaaaaac catccagaat ccttgcctta gcttagatcc
     5461 tggatggttt cttttttcac ccaatgggtg ttttttacta gacaaaaaag agtttcccct
     5521 ttatggtata agtgtagaaa aaaacacaaa aagaaaggaa actcacatga acagtttacc
     5581 aaatcatcac ttccaaaaca agtcttttta ccaactatct ttcgatggag gtcatttaac
     5641 ccagtatggt ggtcttatct tttttcagga acttttttcc cagttgaaac taaaagagca
     5701 gatttctaag tatttagtaa cgaatgacca acgccgctac tgtcgttatt cggattcaga
     5761 tatccttgtc cagttcctct ttcaactgtt aacaggctat ggaacggact atgcttgtaa
     5821 agaattgtca gctgatgcct actttccaaa attgttggaa ggagggcagc ttgcttcaca
     5881 gccaacctta tcccgttttc tttccagaac tgacgaggaa acagtccata gtttgcgatg
     5941 cctcaacctt gaattggtcg aattcttttt acagtttcac cagctaaacc aactcattgt
     6001 agatatcgat tctacccatt tcacaactta tggcaagcaa gaaggtgttg cttataacgc
     6061 tcactatcgt gctcatggct atcatcctct ttatgctttc gaggggaaga caggttattg
     6121 tttcaatgct cagcttcgtc ctggtaatcg ttattgttct gaagaggcag acagctttat
     6181 cacacctgtt ttagaacggt ttaatcaact tctctttcga atggatagtg gctttgcgac
     6241 ccccaaatta tacgatttaa ttgaaaaaac agggcaatac tacctcataa aactcaagaa
     6301 aaatactgtt ctgagccgtc ttggagacct ttccctccct tgcccacagg atgaggactt
     6361 aaccatcttg ccccactccg cctactcaga aactctctat caagcaggat cttggtcgca
     6421 caagcgtcgt gtctgccagt tctctgaacg aaaagaagga aacttgttct acgatgttat
     6481 ttctctcgtt acaaatatga cgagtggaac aagccaagac cagtttcagc tttatcgtgg
     6541 acgtggtcaa gccgagaatt tcatcaagga gatgaaggag ggattttttg gcgataaaac
     6601 ggatagttca accttaatca aaaacgaagt tcgtatgatg atgagctgta tcgcctacaa
     6661 tctctatctt tttctcaaac atctagctgg aggtgacttc caaactttaa caatcaaacg
     6721 cttccgccat ctttttcttc acgtggtagg aaaatgtgtt cgaacaggac gcaagcagct
     6781 cctcaaattg tctagtctct atgcctattc cgaattgttt tcagcacttt attctaggat
     6841 tagaaaagtc aacctgaatc ttcctgttcc ttatgaacca cctagaagaa aagcgtcgtt
     6901 aatgatgcat taaagaacag tcgagatgaa aaaatcgtgt gacgcaccaa gggaggagtc
     6961 tgcccttttg aggaaatcta gcgaggaaaa acgatactgg aacagcagaa agtaaaactg
     7021 acctcatgag gaggaagaaa gtggctcatg aggtcagggg ttttgtaagt tacatctagt
     7081 tgagagaggt atgaatgatt tggggttaca gagagccgat tataaatagt taacttagga
     7141 tagattggtt atatata
//
LOCUS       DAVKMO010000070         7003 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVKMO010000070 DAVKMO010000000
VERSION     DAVKMO010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7003
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.070"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..437
                     /locus_tag="VW361_001895"
                     /pseudo
     CDS             1..437
                     /locus_tag="VW361_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            592..792
                     /locus_tag="VW361_001896"
     CDS             592..792
                     /locus_tag="VW361_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744880.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRVLSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            834..1238
                     /locus_tag="VW361_001897"
     CDS             834..1238
                     /locus_tag="VW361_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744881.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1469..2176
                     /gene="ccdA2"
                     /locus_tag="VW361_001898"
     CDS             1469..2176
                     /gene="ccdA2"
                     /locus_tag="VW361_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9744882.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2187..2744
                     /gene="sdbB"
                     /locus_tag="VW361_001899"
     CDS             2187..2744
                     /gene="sdbB"
                     /locus_tag="VW361_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU9744883.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            3119..4510
                     /locus_tag="VW361_001900"
     CDS             3119..4510
                     /locus_tag="VW361_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU9744884.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4653..5570
                     /gene="adcAII"
                     /locus_tag="VW361_001901"
     CDS             4653..5570
                     /gene="adcAII"
                     /locus_tag="VW361_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU9744885.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5578..>7003
                     /gene="phtD"
                     /locus_tag="VW361_001902"
     CDS             5578..>7003
                     /gene="phtD"
                     /locus_tag="VW361_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEU9744886.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNEL
                     SASELAAAEAYWNGKQGSRPSSSSSYNANPVQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIA
                     RIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRK
                     VGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFY
                     NKAYDLLARIHQDLLDNKGRQVDFE"
BASE COUNT         2161 a         1285 c         1474 g         2083 t
ORIGIN      
        1 agacgcttat ttgactgaaa tagcttctga atttggctgt catccaacta ccatccacta
       61 tgcgctcaaa gctatgggct acactcgaaa aaaagaacca cacctactat gaacaagacc
      121 cagaaaaagc agccttattt cttaagaatt ttaatagttt aaagcaccta gcacctgttt
      181 agattgatga aacaggattc gatacttatt tttatcgaga atatggtcgc tcattaaaag
      241 gtcagttaag aagaggcaaa gtatctggaa gaagatatca gaggatttct ttggttgcag
      301 gtctaacaaa tggtgagtta atcgttccaa tgacttacga agagacgatg acgagcgact
      361 tttttgaagc ttggtttcag aagtttttct taccaacatt aaccacacca tcggttatta
      421 tagtaaaacg aaataagaat aggacaaatc gatcaggaca gtaaaatcga attctaacaa
      481 tgttttagaa gtccatatgt actattctag tttcaatata ccataactgc tcctagtcaa
      541 cctgcaagtc ctggcccagc tccaagctca gctccgactc aagatcctag agtggtagca
      601 agcgcttcgg ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt
      661 cgtgtcttga gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatccg
      721 aaaatcgatg caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc
      781 ttgacagagt aaggtctgca tactgcagta gagtctgtga aggctgggct gccttggact
      841 ctctcaaaga tgtgaaagca aatgctagcg acagcaagcc tgcacaggac aagaaggatg
      901 caaaacaagg aacggaagat agtaaggatt cagataagat gactgaaaca aactcagttc
      961 cggcaggagt gattgtggtc agtctacttg ccctcctagg cgtgattgcc ttctggctga
     1021 ttcgccgtaa gaaagagtca gaaatccagc aattaagcac ggaattgatc aaggttctag
     1081 gacagctaga tgcagaaaaa gcggataaaa aagtccttgc caaagcccaa aaccttctcc
     1141 aagaaaccct tgatttcgtg aaagaagaaa atggctcagc agagacagaa actaaactag
     1201 tagaggagct taaagcaatc cttgacaaac tcaagtaaaa catgatttat gaaatgtcag
     1261 acctaaaaga cattttcgtt cacaaaagca gcgatgagta atccttgtcg ttgctttttg
     1321 gctattttgg gggataagat ccgccttgac tagcaaaaga aaagattggt ccaatagtgc
     1381 ccgatacgat tttgcgtagc agaaagctta caaataaaat tgaatatagt aaaataggat
     1441 tagaattatt aagaaagttg gttctttatt ggaaacgata gtatttttaa tctctgtttt
     1501 tctagcaggt gttttatcct ttttttctcc ttgtattttt cctcttctgc cagtctatgc
     1561 tgggatttta ttggatgatc aagaaagtgc aaaaagcttt tctttgtttg ggagaaaggt
     1621 tctctggtca ggcttgattc gaacactttg ctttatcgct ggtatctctc tcattttctt
     1681 tattctaggc tttggtgctg gttactttgg tcatattctc tatgcaaatt ggtttcgata
     1741 tgtcatggga gctattatta tcattttggg tcttcaccag atggaaattt ttcatttgaa
     1801 gaaattagaa gttcaaaaaa gttttacctt taaaaaatca gattctaatc gttattggtc
     1861 agctttttta cttggtatta cctttagctt tggttggaca ccttgtattg gtccagtttt
     1921 aagttctgtt ttagcacttg cggcttctgg aggcaatggt gcttggcaag gagcgattta
     1981 tactctcatt tacactctgg gcatggccct tcctttcttg gtcttggcac tagcttcagg
     2041 tctagtcatg ccatatttta gtaaaatcaa gcgtcatatg atgctactaa agaaaattgg
     2101 tggtttcctc attgttttaa tgggaatttt gttactatta ggacaagtaa atgttctagc
     2161 tggaattttt gaataaagga ggacaaatga aaaaagtaat gtttgctggc ttaagtctct
     2221 tgtcattagt tgtattgatg gcctgtggtg aggaagaaac taaaaagact caagcagcac
     2281 aacagccaaa acaacaaacg actgtacaac aaattgctgt tggaaaagat gctccagact
     2341 tcacattgca atccatggat ggcaaagaag ttaagttatc tgattttaag ggtaaaaagg
     2401 tttacttgaa gttttgggct tcatggtgtg gtccatgcaa gaaaagtatg ccagagttga
     2461 tggaactagc ggcgaaacca gatcgtgatt tcgaaattct tactgtcatt gcaccaggaa
     2521 ttcaaggtga aaaaactgtt gagcaattcc cacaatggtt ccaggaacaa ggatataagg
     2581 atatcccagt tctttatgat accaaagcaa ccaccttcca agcttatcaa attcgaagca
     2641 ttcctacaga atatttaatt gatagccaag gaaagattgg aaagattcaa tttggtgcta
     2701 tcagtaatgc ggatgcagaa gcagcattta aagaaatgaa ctagaatcga taaaatctga
     2761 ttacaagatg tagtcagatt ttggtaactt ctaaaactaa cttctagttt cccacaacct
     2821 agcttttagt atgagaaaaa cgtgtgacac cagtggaaat ccgtcttaga ctaacttcca
     2881 ctggttttct ttttcttgat atataagggt tcaaaagcga aaagactcag aaaaaagtgc
     2941 acgacaaata gccctaaaac agagtcgttt tagagtaact tccagttttg ggagagagat
     3001 ggaagttact ttgagaagtt acggtagtca gattttttta gaaaaacatt ttataaatat
     3061 tcacatatct cctatattta tggtaaaata gaatcatcag tttattttgg agtcaaagat
     3121 gaatatattt agaacaaaga atgttagttt agataaaaca gagatgcata ggcatttgaa
     3181 gttatgggat ttgattttgc tgggtattgg agccatggta gggacaggtg tctttacaat
     3241 cacaggtact gcagctgcta cacttgctgg tccagcacta gtgatttcaa tcgttatttc
     3301 tgccttgtgt gtgggattat cagccctctt ttttgcagaa tttgcctcgc gagtacccgc
     3361 tacaggaggt gcctatagtt acctctatgc tatcttagga gaattccctg cctggttggc
     3421 tggttggtta accatgatgg agttcatgac agccatatca ggcgtagctt cgggttgggc
     3481 agcttatttt aaaggcttgc tctctcaata cgggatagcc cttcctcagg ctttaaatgg
     3541 tacctttaat cctcaagcag ggacatttgt tgatttattg cctattcttg tcttggtctt
     3601 ggtgacttcg cttgttttac taaatgccaa ggcagcctta cgctttaatt cgattctagt
     3661 tattttgaaa ttttccgctt tagctctctt tgttttagta ggaatttgga atattaagtt
     3721 tgataattgg agcaattttg ctccttacgg ttttggacaa atctatggag ctagtactgg
     3781 tattatggct ggtgcgtcct tgatgttctt cggttttttg ggatttgaat ccatctctat
     3841 ggctgtagat gaagtcaaga ctcctcaaaa aaatattcct agagggattg tcttatcgct
     3901 ttctatcgta accattctct atgccttggt gacccttgtt ttgactggtg tggttcacta
     3961 tagtcattta aatgtcgatg atgccgttgc ctttgccctt cgtagtgttg ggattagttg
     4021 ggcagccaac tatgtgtcat tagtggctat cttgaccttg attacagttt gtatttcgat
     4081 gacctatgcc ctatcgcgta tgatttacag tttagcacgt gacggcttag tgcctgctgc
     4141 ctttaaggaa ctgacgaaga ctagcaagat accaaagaat gctactatct tgacaggtct
     4201 agcttcagca gtagcagcag gaatgttccc actagccagt attgcagcct ttttaaatat
     4261 ttgtacctta gcctacttga tcatgctggc ttatggtctg attcgcttac ggaaagaaaa
     4321 aggaatgccc aaagctgggg aatttaaaac accattggta cctctgttac caattttatc
     4381 gatcatcatt tgtttatcct tcatgttaca gtataatatg aacacctgga ttgctttcct
     4441 agttgcgttg ttagtaggaa gtattattta cttcacttat ggctataagc attctaccat
     4501 agaagaataa agtgaaagtc tattgagttg ttgacactca gtagattttt atatgtgaaa
     4561 gaaatttcaa attttttcta aaaatatctt gacagattaa attttcagga gtagaatatt
     4621 tactagttaa ttaaatggtt aaggagttgt tcatgaagaa acaaaattta tttttagtcc
     4681 tgttaagtgt ctttcttttg tgcttggggg cttgtggtca aaaggaaagt cagacaggaa
     4741 aggggatgaa aattgtgacc agtttttatc ctatctacgc tatggttaag gaagtatctg
     4801 gtgacttgaa tgatgttcgg atgattcagt caagtagtgg tattcactcc tttgaacctt
     4861 cggcaaatga tatcgcagcc atctatgatg cagatgtctt tgtttaccat tctcatacac
     4921 tcgaatcttg ggcaggaagt ctggatccaa atctaaaaaa atccaaagtg aaggtcttag
     4981 aggcttctga gggaatgacc ttggaacgtg tccctggact agaggatgtg gaagcagggg
     5041 atggagttga tgaaaaaacg ctctatgacc ctcacacatg gctagatcct gaaaaagctg
     5101 gagaagaagc ccaaattatc gctgataaac tttcagaggt ggatagtgag cataaagaga
     5161 cttatcaaaa aaatgcgcaa gcctttatca aaaaagctca ggaattgact aagaaattcc
     5221 aaccaaaatt tgaaaaagcg actcagaaaa catttgtaac acaacataca gccttttctt
     5281 atctagcgaa gagatttggg cttaatcaac ttggtattgc aggcatctct cctgaacaag
     5341 aaccaagtcc acgacaatta acagaaattc aggaatttgt taaaacctat aaggttaaaa
     5401 cgatttttac agaaagtaat gcttcttcaa aagtagctga aactcttgtc aaatcaacag
     5461 gtgtgggtct taaaactctg aatcctttag aggcagaccc acaaaatgac aagacctatt
     5521 tagaaaatct ggaagaaaat atgagtgttc tagcagaaga attaaagtga ggaaagaatg
     5581 aaaatcaata aaaaatatct agcaggttca gtggcagtcc ttgccctaag tgtttgttcc
     5641 tatgaacttg gtcgtcacca agctggtcag gttaagaaag agtctaatcg agtttcttat
     5701 atagatggtg atcaggctgg tcaaaaggca gaaaatttga caccagatga agtcagtaag
     5761 agagagggga tcaacgccga acaaattgtt atcaagatta cggatcaagg ttatgtgacc
     5821 tctcatggag accattatca ttactataat ggcaaggttc cttatgatgc catcatcagt
     5881 gaagaacttc tcatgaaaga tccgaattat cagttgaagg attcagacat tgtcaatgaa
     5941 atcaagggtg gctatgtgat taaggtagac ggaaaatact atgtttacct taaagatgcg
     6001 gcccatgcgg acaatattcg gacaaaagaa gagattaaac gtcagaagca ggaacacagt
     6061 cataatcata actcaagagc agataatgct gttgctgcag ccagagccca aggacgttat
     6121 acaacggatg atgggtatat cttcaatgca tctgatatca ttgaggacac gggtgatgct
     6181 tatatcgttc ctcacggcga ccattaccat tacattccta agaatgagtt atcagctagc
     6241 gagttagctg ctgcagaagc ctattggaat gggaagcagg gatctcgtcc ttcttcaagt
     6301 tctagttata atgcaaatcc agttcaacca agattgtcag agaaccacaa tctgactgtc
     6361 actccaactt atcatcaaaa tcaaggggaa aacatttcaa gccttttacg tgaattgtat
     6421 gctaaaccct tatcagaacg ccatgtagaa tctgatggcc ttattttcga cccagcgcaa
     6481 atcacaagtc gaaccgccag aggtgtagct gtccctcatg gtaaccatta ccactttatc
     6541 ccttatgaac aaatgtctga attggaaaaa cgaattgctc gtattattcc ccttcgttat
     6601 cgttcaaacc attgggtacc agattcaaga ccagaacaac caagtccaca atcgactccg
     6661 gaacctagtc caagtctgca acctgcacca aatcctcaac cagctccaag caatccaatt
     6721 gatgagaaat tggtcaaaga agctgttcga aaagtaggcg atggttatgt ctttgaggag
     6781 aatggagttt ctcgttatat cccagccaag gatctttcag cagaaacagc agcaggcatt
     6841 gatagcaaac tggccaagca ggaaagttta tctcataagc taggagctaa gaaaactgac
     6901 ctcccatcta gtgatcgaga attttacaat aaggcttatg acttactagc aagaattcac
     6961 caagatttac ttgataataa aggtcgacaa gttgattttg agg
//
LOCUS       DAVKMO010000071         6886 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVKMO010000071 DAVKMO010000000
VERSION     DAVKMO010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6886
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.071"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(565..1557)
                     /locus_tag="VW361_001903"
     CDS             complement(565..1557)
                     /locus_tag="VW361_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9744887.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            1717..3471
                     /locus_tag="VW361_001904"
     CDS             1717..3471
                     /locus_tag="VW361_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744888.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNEGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            3455..5176
                     /locus_tag="VW361_001905"
     CDS             3455..5176
                     /locus_tag="VW361_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744889.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     EDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSIMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            5187..5816
                     /locus_tag="VW361_001906"
     CDS             5187..5816
                     /locus_tag="VW361_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9744890.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            5717..6274
                     /locus_tag="VW361_001907"
     CDS             5717..6274
                     /locus_tag="VW361_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9744891.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            6262..>6886
                     /locus_tag="VW361_001908"
     CDS             6262..>6886
                     /locus_tag="VW361_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744892.1"
                     /translation="MVEIKNLSLDYGEKHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDR"
BASE COUNT         2468 a          946 c         1194 g         2278 t
ORIGIN      
        1 ttgaacttac aatcgaaaaa tggttaagta aaagtcaaca gttactatag tttgcaaatt
       61 atttacagaa agaacaaaaa atgctctgaa acactgattt caaagcattt tttgttagtt
      121 taaaattact cccattcttc ttttccaaac gtacaatata tccaaaacca ttcaaaatac
      181 tagattctat tttttataat atcactaaat ccacctaatt ataggacgtt ttcagatttt
      241 tagtcccgtc ccagtcccag taccggagaa atattgtttt aatataatat ctctttttgt
      301 cttctaagct cttaaaagca aaagaacaag taaagagtca agacaaggat aaaaagtcca
      361 tattagggca aataaaaagc tttaagacag atgacaaatc taagtcaaat aagaaagacc
      421 atagcaaagg tgcagagaga taaatattgg cggtcttcgg actgccttta tttttttatc
      481 catttttcaa atcaaattta ttcagactat atatgcacat atacacttaa attcatataa
      541 aaacatggct tgtaaaaaat tactttaatc acaataatcg catttaaaat tgtgatgttt
      601 gcaagctaaa ttacggactt cacttggaag ttttcccttg tatcttttat aatagataga
      661 aaatttgctg gcagatgaat atccaacaga ttctgctatc tcttttatag gtagttcagt
      721 gtttaaaaga agagtttcag ctacattcat tctttttctt tgagtgtact ctgtaatgct
      781 ttgacaatat ttttccttaa ataaattttt taatttagta ccactcattt tagatatttt
      841 ttcaagcgtg ccttgattta cattcgttgc aaaatgatca tctaagaatc ttgctacatc
      901 ttcaagtgct ttatcatcat caatttcaat tttatatttt tttctattta agtatgtgtc
      961 aattactata cttatccatt catttgcctt tgctttaaag aaaaaatcag cggcaggagc
     1021 gtccatctta caatttaata tttccattgc cactctttct aaggcctttg taagtattat
     1081 ttgattcggt tgaagcaagg ttgaataaaa agattctgga ttaatgttaa tagatgctaa
     1141 atgtttttct attagctctt ttttaaaacc aatggaaaca gcaagataac aacaattctc
     1201 gtgtaataaa aaaacaaaat catcttttat attatcaaaa tcaaaagtac ataaagagtt
     1261 tgcggtaata gtttgatacg gattaaactt ttctccgttt gcactgacaa tataacttga
     1321 ataaattgaa acatagtctg acatactata agtgctattt tgaactactt cctctttgat
     1381 ataaaaatca tgtatatcga taatgaagct gcctccttca taaaaccaat ataggccttc
     1441 tgcataagtt gaattctctt ttttccaaca aaatgtatga cctgcacttg aatacttctc
     1501 attgttttta cattcatcta ctttcatata atcttttaca aaatcataat atgacataac
     1561 acactatccc ttttagacaa tattccaatt agccttatta attcaaaact attgtattag
     1621 taattataac agatgtataa tagaaaagca atgatagata ttatcaatta agcgaattta
     1681 tatctaaaag ggatattaaa gaaaggagat atgcttatga agatttacaa aaaactattt
     1741 gcttatgtcc aagataagaa atatcttggg gttttggcca taattttttc tgctatatct
     1801 gctgcactta cagtatatgg atattattta atctacaaat ttctagataa gttaataatt
     1861 aattcaaact tatccggtgc agagagtata gcattaaaat ctgttattac actaacaagt
     1921 ggagcgatat tttattttgt ctcaggaatg ttttcacata tcttgggatt taggcttgaa
     1981 acaaatttaa gaaaaagggg aatcgatggt ctggaaaaag caagttttag gttctttgac
     2041 ttaaatccat ctggtcaaat aagaaagatc atagatgata atgcagcaca aactcatcag
     2101 gtggtagctc acatgattcc agatagctct caggcaatag tcacacctat acttgtcctt
     2161 gtactaggct ttatagtaag tataagagtt ggcataattt tgcttgctct tactataatt
     2221 ggtggcttaa ttttaggggc aatgatgggc gagcaagaat ttatgaagat ataccaagaa
     2281 tccctatcta aactaagtgc tgaaactgtt gagtacgtga gaggaatgca agttgtaaaa
     2341 atatttaaag caaatgtaga gtcatttaaa agcttttaca aggctataaa agattactca
     2401 aagtatgctt atgattattc cctatcttgt aaaaggcctt atgttttgta tcaatggtta
     2461 ttttttggac tgattgcaat tttaattatt cctatagttt attttatgac tagcttagct
     2521 agcgcaaagg tgattttact tgagcttatc atgattttat ttttatcagg agttctcttt
     2581 gtttcattca tgagaatgat gtggtactcc atgtatattt ctcaaggaaa ttatgcagta
     2641 gatactttag aggcgcttta cgaagatatg caaaaagaca aattagtgca tggtaatgtc
     2701 aataatttta aaaactataa tatagaattt gagaatgtta gctttgctta taatgataaa
     2761 gctgtcattg aaaatttatc ctttaattta gaagaaggaa agtcctacgc acttgtcggt
     2821 tcatctggat caggcaaatc aacagtagca aaacttatat caggttttta caatgttaat
     2881 gaaggaagca taaagatagg cgggatagca ataagtgaat attctgacga agccttaatt
     2941 aaagccattt cctttgtttt tcaagattca aaattattca agaagagcat ttatgataat
     3001 gtagctttag ctaataaaga tgcgacgaaa gatgacgtta tgagagcctt aaaattagca
     3061 ggatgcgatt taatattaga caaattccca gaaagagaaa atacaatcat aggctcaaaa
     3121 ggtgtttatt tatccggtgg agaaaaacaa agaattgcaa ttgctagagc aattttaaag
     3181 gattccaaaa ttattattat ggatgaagca tcagcatcta ttgacccaga taatgagttt
     3241 gaattgcaaa aagcttttaa aaatcttatg aaggataaaa cagttatcat gattgcacac
     3301 aggctatcta caattaaaga ccttgatgaa attattgtca tggatagtgg aaaaattata
     3361 gaaagagggt ctgacaaaga attaatgtca aaagatacaa ggtataagag cctgcaagag
     3421 atgtttaaca gtgcgaatga atggagggtt tcaaatgaaa gagttttata aaaaaagatt
     3481 tgctcttaca gatggaggag caagaaattt aagtaaagca acactggctt catttttcgt
     3541 ttattgtata aacatgcttc ctgccatatt acttatgatt tttgctcagg aagttttgga
     3601 aaatatgggc aaaagcaatg gcttttatat agtattctca gttttgactt tgatagcaat
     3661 gtatattttg ctttctatcg aatacgataa attatataac acaacctatc aagaaagtgc
     3721 agatttaaga ataaggacag cggagaattt atcaaaatta cctctatctt acttttctaa
     3781 acatgacatt tccgacattt cacaaacaat catggctgat attgaaggca tagagcatgc
     3841 aatgagccac tcaataccaa aggtgggcgg catggtactg tttttcccat taatatctgt
     3901 aatgatgcta gcgggcaatg tcaagatggg tttagctgta attattccat ctattttaag
     3961 ctttatattt atacctttat ctaaaaaata tcaggttaat ggacagaata gatattatga
     4021 tgtcttaaga aaaaactcag aaagctttca agaaaatatc gaaatgcaaa tggagattaa
     4081 agcatataat ttatcgaagg atattaaaga agacttatat aaaaaaatgg aagatagtga
     4141 gagagtacac ttaaaggcag aagtaactac aattttaact ttgtctatat cttcaatatt
     4201 tagctttata tctcttgctg ttgtgatatt tgtcggcgta aatctaatta ttaataaaga
     4261 gataaattct ctctacctta taggatattt actagctgct atgaagataa aagactcttt
     4321 agatgcatct aaagagggct tgatggaaat attttattta tcgcccaaaa tagaaagatt
     4381 aaaagaaatt caaaatcaag atttacaaga aggcgatgac tatagcttaa aaaaatttga
     4441 tattgatcta aaagatgttg agtttgccta caataaagac gcaaaagttt taaatggtgt
     4501 aagttttaaa gctaagcagg gagaggtcac tgctttggta ggtgcaagtg gctgcggtaa
     4561 aacaactatc ttgaaactta tatcaagact ttatgattat gacaagggac aaatcttaat
     4621 cgatggcaaa gatataaaag aaatatcaac agaatctctt tttgataagg tctctatagt
     4681 tttccaagat gtggttctct ttaatcaaag cattatggaa aatattagaa tcggaaagca
     4741 agatgcaagt gacgaagagg ttaaaagagc agcaaaactt gcaaattgca cagattttat
     4801 agaaaaaatg gataaaggtt tcgatacagt tattggtgag aacggagctg agctatcagg
     4861 aggagaaaga caaagattat caatagccag agccttctta aaagatgcgc cgatattgat
     4921 cttagatgag ataacagcaa gccttgatgt taacaacgag aaaaagattc aagagtcttt
     4981 aaataattta gttaaagata aaactgttgt aatcatttca catagaatga aatccataga
     5041 aaatgcagac aagatagtag ttcttcaaaa cggaagagta gaaagcgaag gtaagcatga
     5101 agagctttta caaaaatcaa aaatttacaa aaatttaata gaaaagacaa aaatggcaga
     5161 agaatttatt tattaggagg actacaatgg ataataaaaa attaaaagta aaagatttag
     5221 taagtatcgg tgtttttggc gtaatttatt ttgccttcat gtttggagtt ggtatgatgg
     5281 gcttgattcc aatattgttc ttaatatacc cgacagtatt agccatagtt gcaggaactg
     5341 ttgttatgtt atttatggct aaggttcaaa agccatgggc actatttata tttggtatga
     5401 tatcaccact tgtgatgttt gcagctggtc atacctacgt agttgtggtt ttatcactta
     5461 tagtaatgat aatagcagaa ttaattagaa agattggtaa ttataattca tttaaataca
     5521 atatgctttc ttatgcaatc ttcagcacat ggatatgtag ctctttaatg caaatgcttt
     5581 tagcaaaaga aaaatatatg gagtggtctt tgatgacgat gggaaaagat tatgttgatg
     5641 tattagaaaa gttaataact tatcctcaca tggctttagt agccttaggt gctttcttag
     5701 gaggaattct tggagcatat ataggcaagg ctctattgaa aaaacacttt tcaaatggat
     5761 tatattgtgt gggatacttt actccttgcc taattttatg gtgttatctg aattaaaccc
     5821 tatagttaag atgtttttga gtatacctat tgttattaga atgtttattt taccatttat
     5881 ggcagcaagc tttatgataa agacctcgga tgtaggcgca ataatttcat cgatggataa
     5941 gcttaagatt tcaaagaatg tatccatacc tattgcggtt atgtttagat tcttcccatc
     6001 ttttaaggag gagaagaaaa acatcaaaat ggctatgaga gtaagaggga taaattttaa
     6061 aaacccagtc aaatatcttg aatatgtttc tgtaccacta ctcattatat catctaatat
     6121 atcagatgac attgcaaaag cggcagaaac aaaggcaata gaaaatccaa ttgctaagac
     6181 cagatacatt cgcgtaaaga tacagctaat tgattttgtt tatgttttag cggttgctgg
     6241 acttattgtg ggaggcttaa tatggttgaa ataaaaaatt taagtcttga ttatggtgaa
     6301 aagcatatat tagatgatat atcactatcc atagccgagg gagagtgcgt gctatttaca
     6361 ggaaaaagtg gaaatggtaa gtcatcttta ataaattcaa tcaatggact agctgtaagg
     6421 tatgataacg caaagacaaa gggcgaaata attattgatg gtaagaatat aaaaaatttg
     6481 gaactttatc aaatctcaat gcttgtttca actgtttttc aaaatcctaa gacatatttt
     6541 tttaatgtca atacgacatt agaattatta ttttatttgg aaaatatcgg tcttgcaaga
     6601 gaagagatgg acaggcgttt gaaggatata cttgagatat tcccgataaa aaatcttttg
     6661 aacagaaata tatttaatct atccggcggt gaaaaacaaa ttctttgcat tgcagcttct
     6721 tatatagcag gtacaaagat tatagttatg gatgagcctt catcgaattt agatattaaa
     6781 agcataagtg ttttggcaaa gatgctaaag atattaaaag agaaaggcat aagcataatt
     6841 gttgcagagc atagaattta ttatttgatg gacatagttg accgtg
//
LOCUS       DAVKMO010000072         6745 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVKMO010000072 DAVKMO010000000
VERSION     DAVKMO010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6745
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.072"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            186..1049
                     /locus_tag="VW361_001909"
     CDS             186..1049
                     /locus_tag="VW361_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9744893.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFAYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            1432..2052
                     /locus_tag="VW361_001910"
     CDS             1432..2052
                     /locus_tag="VW361_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744894.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2138..2581
                     /gene="tsaE"
                     /locus_tag="VW361_001911"
     CDS             2138..2581
                     /gene="tsaE"
                     /locus_tag="VW361_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU9744895.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2571..3089
                     /locus_tag="VW361_001912"
     CDS             2571..3089
                     /locus_tag="VW361_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744896.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            3097..4113
                     /locus_tag="VW361_001913"
     CDS             3097..4113
                     /locus_tag="VW361_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU9744897.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4197..5453
                     /locus_tag="VW361_001914"
     CDS             4197..5453
                     /locus_tag="VW361_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU9744898.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKVSSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5508..6674
                     /gene="recA"
                     /locus_tag="VW361_001915"
     CDS             5508..6674
                     /gene="recA"
                     /locus_tag="VW361_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU9744899.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
BASE COUNT         2134 a         1097 c         1503 g         2011 t
ORIGIN      
        1 tgaaaccctt ttctttttcc ttgtttttat tttaatatat atatattatt cggtcaagca
       61 tttttatgta atttttgact ttttttagtt tattaccata aagaattatt tattccttta
      121 acttgctatt ttgaactaaa aattttataa tgcaattaag caaataggaa ggtttattat
      181 ctttaatgaa tacactcgca gagaaattca gattgaaaag aaaagagttg agactctccc
      241 aacaaactct tgcagaagga atttgtgaac aaagccagat tagtaaaatt gagagagggc
      301 atttcattcc ctccgcagac cttttgttca aactctctca acgacttgaa gtaccattag
      361 attatttttt taatgaacaa attgaaatta aatctaacct ctctaatttc aagcaattgt
      421 ctgctcgact attagacgat agaaattatg acgatttgga atatatttat agaatagaga
      481 ttgaacgaag tacttttcta acactagaag accgaactta ccttgaatgg attaaagcta
      541 ttattgactt ctatcaatat gacagtaagt gtgaggcaat ttcttcattg gaaaatatat
      601 tattaaaagt ctcttcaaat actctgattt atttaaaggc gttgaatact ctatctaatt
      661 tctattcctt agtgggtcgt gaacaagaat atgaggcaaa ctactctcat ttaatagagt
      721 tgtatcagac aaaaaatttg gaccatcaag agtttttatt tgcctacatc agagttcgtt
      781 acaactacgc tcactaccta gtatcaaagg aaaaatataa tgaagccatc caagaagctc
      841 ttgaaacgat tgaactctgt aaacaaagac agacaagcta ccaattggct cctctactta
      901 ttcttgtagg aaatgctgga gccaaatttc tagacagaga acaagtcaaa aattattata
      961 tagaagcaag agagttatgt aagatttata acaatccttt aatgttgatg aagatagaaa
     1021 attatttgaa ggaactagat actgtttagt taatcttgac attatagttt ttctgaaacg
     1081 ttaaataacc tgtaaggctg atagttagat taatactatc agccttataa ttatgtgact
     1141 ctgagtccgt ctcgctccgt gaggtgcgag acaaaacaac cacccgtttg acggattttc
     1201 atgatttcaa atttatattc ttcgaaaatc tcttcaaacc acgtcagctc tatctgcaat
     1261 ctcaaaacag tgttttgagc aacctgtggc tagctaccta gtttgctctt tgattttcat
     1321 tgagtattag tctctagtgt ttgtttagcg tcttaaagag acatttgaga agattagaaa
     1381 cagttctctc ttttctccta gtataatgat tggtaggaag ggagagagaa gatgaaatca
     1441 atgagaatct tatttttgtt agctttaatt caaatcagtt tgagtagctg tttcctatgg
     1501 aaggaatgca tcttgtcctt taaacaaagt acagcttttt tcatcggaag catggttttc
     1561 gtttcaggaa tctgtgctgg agtaaattat ctttataccc gtaagcaaga agtccatagt
     1621 gtcctagcca gtaagaagtc ggtgaagctt ttttacagta tgttactctt aattaatttg
     1681 ttaggagctg ttcttgtttt gtcagataac ttgttcatca aaaatacgct gcagcaagaa
     1741 ttagttgact ttttattgcc atccttcttt ttcctatttg ggctagattt gctgattttt
     1801 ttacccttga aaaaatacgt gcgcgatttt cttgctatgc tagacagaaa aaagacagtg
     1861 ttggtgacta ttttagcaac acttcttttc ttaagaaatc caatgaccat tgtctcactt
     1921 ctgatttata ttggactggg cttgtttttt gcagcctatc ttgtcccaaa ttcggttaag
     1981 aaggaagttt ccttttatgg tcatattttc cgagatcttg tattggtcat tgttacgctc
     2041 attttctttt agagaaagcc tgttttttat ggatgttatg atgataagtt tagtaggaaa
     2101 atagacacaa aagaaaagtt tttggtataa taagagtatg tacacaaaaa atgaagaaga
     2161 gttgcaagcc ttaggggagc gtttgggcca tctattagca aagaatgatg ttttaatctt
     2221 aactggagaa ctgggtgcag gtaaaacgac ctttactaaa ggacttgcaa aaggattaca
     2281 gatttctcaa atgattaaaa gtcccaccta tactatcgtg agagagtatg aaggtcgact
     2341 tccactttat cacctagatg tttatcgtat tgaaggagat gctgattcta tcgacttgga
     2401 tgagtttatc tttggtggcg gcgtgactgt tattgagtgg ggaaatctct taggagatgc
     2461 cttgccagat gcttatttag aattggaaat tctaaaagaa gcagatggac gccgtttaaa
     2521 ttttcaggca aagggtttgc gtgctgagaa attgttagag gagcttcaat atggagtatg
     2581 aattgctcat tagggaagca gagcccaaag atgcagctga attagtggcc tttttaaatc
     2641 gtgtgagttt ggagacagac tttaccagcc tagacggaga tggtattctc ttgactagtg
     2701 aggagatgga aatattcctc aacaagcaag ctagttcgga caatcagata accttacttg
     2761 cattcttaaa tggcaaaatt gctggtattg taaatattac agctgaccag cgtaagagag
     2821 tccgtcatat tggagatctc ttcattgtga ttggaaaaag atattggaat aatggcttgg
     2881 gaagtttgtt gctagaagaa gcgatagagt gggcacaagc aagtggcatt ctgcgtcgtc
     2941 tccaactgac tgtccaaact cgtaatcaag cagcagtcca tctttatcaa aagcatggct
     3001 ttgtcattga aggtagccaa gagcgtgggg catatataga agaagggaaa tttatcgatg
     3061 tttacttgat gggtaaactg ataggttagt agaaatatgg ttaaaaaaat tattggaatg
     3121 gtgctagctt tactttctgt aactgtagta ggagtaggtg tttttgctta tactatttat
     3181 caacaaggga cagaaacctt agctaaaacc tataaaaaaa tcggcgaaga aaccaaggtt
     3241 attgaagcga ctgaacctct aaccattctg ttaatgggag tggacaccgg aaatgttgaa
     3301 cgaactgaaa cttgggtcgg tagaagtgat agcatgatct tgatgacagt gaatcctaaa
     3361 acgaaaaaaa caacaatgat gagtttagag cgggatattc tgacgcgcat tgaatcaggg
     3421 aatggtcagg ctcatgaagc gaaactgaac tcagcatatg cagatggtgg agcagagctt
     3481 gctatagaaa ccattcaaaa aatgatgaat atccatattg atcgctatgt gatggtcaat
     3541 atgagagggt tgcaaaaact agtggatgca gtaggaggta ttacagtcaa taatatccta
     3601 ggtttcccaa tttctatcag tgaccaagaa gaatttaata ctatttctat cggtgttggg
     3661 gagcaacata ttgggggaga agaagcccta gtctatgcac gaatgcgtta ccaagatcct
     3721 gagggggatt atggtcgtca aaaacgtcaa cgtgaagtta ttcaaaaagt catggaaaaa
     3781 gctctcagtt taaatagcat tggtcattat caagagattc taaaagcttt gagtgacaat
     3841 atgcagacca atattgattt gtctgcaaaa agtatcccta acttgctagg ctataaagat
     3901 tcatttaaaa ccattgaaac tcagcagttg cagggtgaag gagagatact tcaaggtgtt
     3961 tcttaccaga ttgtttcgag agcacatatg ttggaaatgc aaaatatact ccgacgttct
     4021 ttgggacaag aagaagttac tcagcttgaa accaatgcgg ttttatttga agatttattt
     4081 ggcagagcac ctgttggtga tgaagataat taacttttga tacaaataaa aaatcaatcg
     4141 taggaaaatt cctgcgattt tttcaaaaaa atacgaatag ataggtagga ggaaacatga
     4201 aagcagaaat cattgctgtt ggaacagaga ttttgacagg acagattgtc aacaccaatg
     4261 cccagttttt gtcggaaaaa ctagctgaga ttggggtaga tgtatatttt cagacggctg
     4321 taggagacaa tgaagttcgt ctcttgtctt tgcttgagat tgccagtcaa cgtagcagtc
     4381 tggtgatttt gacaggcggt ttggggccaa ctgaggacga cctaaccaaa caaaccctag
     4441 ctaaattttt agggaaagca ttagtctttg atcctcaggc tcaggagaag ttggatatct
     4501 tttttgccct gcgaccagac tatgcccgaa caccgaataa cgaaagacaa gctcaaattg
     4561 tagaaggagc gattccactg ccaaacgaaa caggactggc tgttggagga aaattagaag
     4621 tagacggagt gacctatgtc gtccttccag gtccgccaag tgaattgaaa cccatggtct
     4681 taaaccaact tctacccaag ttgatgacag ggagcaagct gtattcccga gttcttcgtt
     4741 tctttgggat tggcgagagc cagttggtta cgattttggc tgatttaatt gataatcaga
     4801 tcgatcctac cttggcccct tatgccaaga caggagaagt cactctacgt ctgtcaacaa
     4861 aggttagcag tcaagaagag gcgaatcaag cgctggatat cttggaaaat caaatcttgg
     4921 actgccagac tttcgaagga atttctttac gagacttttg ctatggttat ggggaagaaa
     4981 ctagtttagc cagcattgtg gtagaagaac tgaaaaggca agggaaaacc atcgcggctg
     5041 cagagagttt gacggcaggt cttttccaag ctaccgtggc gaatttttct ggagtttcaa
     5101 gtatatttaa gggtggtttt gtgacctata gcttggagga aaaatcaagg atgttggata
     5161 ttcctgccaa gaatttggaa gaacatggtg tggtgtctga atttacagct cagaagatgg
     5221 ctgagcaggc acgaagcaag acccagtctg attttggaat tagtttgact ggagtggcag
     5281 gaccagatag cctagaagga cacccagttg ggacagtctt cataggcttg gcgcaagatc
     5341 aaggaactga ggttatcaag gttaatattg gaggcagaag ccgagcagat gtacgtcaca
     5401 ttgcggttat gcatgccttt aacctagttc gcaaggcttt attaagtgac taacttttga
     5461 tataatagta gataggtctg aggatcatta gaatgtagga gaatagaatg gcgaaaaaac
     5521 caaaaaaatt agaagaaatt tcaaaaaaat ttggggcaga acgtgaaaag gccttgaatg
     5581 acgctcttaa attgattgag aaagactttg gtaaaggatc aatcatgcgt ttgggtgaac
     5641 gtgcggagca aaaggtgcaa gtgatgagct caggttcttt agctcttgac attgcccttg
     5701 gctcaggtgg ttatcctaag ggacgtatca tcgaaatcta tggcccagag tcatctggta
     5761 agacaacggt tgcccttcat gcagttgcac aagcgcaaaa agaaggtggg attgctgcct
     5821 ttatcgatgc ggaacatgcc cttgatccag cttatgctgc ggcccttggt gtcaatattg
     5881 acgaattgct cttgtctcaa ccagactcag gagagcaagg tcttgagatt gcgggaaaat
     5941 tgattgactc aggtgcagtt gatcttgtcg tagtcgactc agttgctgcc cttgttcctc
     6001 gtgcggaaat tgatggagat atcggagata gccatgttgg tttgcaggct cgtatgatga
     6061 gccaggccat gcgtaaactt ggcgcctcta tcaataaaac caaaacaatt gccattttta
     6121 tcaaccaatt gcgtgaaaaa gttggagtga tgtttggaaa tccagaaaca acaccgggcg
     6181 gacgtgcttt gaaattctat gcttcagtcc gcttggatgt tcgtggtaat acacaaatta
     6241 agggaactgg tgaccaaaaa gaaaccaatg tcggtaaaga aactaagatt aaggttgtaa
     6301 aaaataaggt agctccaccg tttaaggaag ccgtagttga aattatgtac ggagaaggaa
     6361 tttctaagac tggtgagctt ttgaagattg caagcgattt ggatattatc aaaaaagcag
     6421 gggcttggta ttcttacaaa gatgaaaaaa ttgggcaagg ttctgagaat gctaagaaat
     6481 acttggcaga gcacccagaa atctttgatg aaattgataa gcaagtccgt tctaaatttg
     6541 gcttgattga tggagaagaa gtttcagaac aagatactga aaacaaaaaa gatgagccaa
     6601 agaaagaaga agcagtgaat gaagaagttc cgcttgactt aggcgatgaa cttgaaatcg
     6661 aaattgaaga ataagctgtt aaagcagtgg agaaatccgc tactttttcg atttttgatt
     6721 caagttttta gattatatat agtag
//
LOCUS       DAVKMO010000073         6307 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVKMO010000073 DAVKMO010000000
VERSION     DAVKMO010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6307
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.073"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            44..1744
                     /locus_tag="VW361_001916"
     CDS             44..1744
                     /locus_tag="VW361_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU9744900.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
     gene            1737..2213
                     /gene="ilvN"
                     /locus_tag="VW361_001917"
     CDS             1737..2213
                     /gene="ilvN"
                     /locus_tag="VW361_001917"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU9744901.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            2279..3301
                     /gene="ilvC"
                     /locus_tag="VW361_001918"
     CDS             2279..3301
                     /gene="ilvC"
                     /locus_tag="VW361_001918"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU9744902.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVTEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            3408..3644
                     /locus_tag="VW361_001919"
     CDS             3408..3644
                     /locus_tag="VW361_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744903.1"
                     /translation="MLADQNKADWSYDENTVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHFPFERAGATKSARYIAKWILRNKKH"
     gene            3882..4238
                     /locus_tag="VW361_001920"
     CDS             3882..4238
                     /locus_tag="VW361_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU9744904.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            4288..5538
                     /gene="ilvA"
                     /locus_tag="VW361_001921"
     CDS             4288..5538
                     /gene="ilvA"
                     /locus_tag="VW361_001921"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU9744905.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
BASE COUNT         1955 a         1046 c         1434 g         1872 t
ORIGIN      
        1 atgatagtaa caagttattt ttaagaggaa agaaagggga ataatggaga aaatcagttt
       61 agaatctcct aagacggggt cggacctagt tttggaaaca cttcgtgatt taggagttga
      121 taccatcttt ggttatcctg gtggtgcggt tttgcctttt tatgatgcga tatataattt
      181 taaaggcatt cgccacattc tagggcgcca tgagcaaggt tgtttgcatg aagctgaagg
      241 ttatgccaaa tcaactggaa agttgggtgt tgccgtcgtc actagtggac caggagcaac
      301 aaatgccatt acagggattg cggatgccat gagcgatagc gttccccttt tggtctttac
      361 aggtcaggtg gcgcgagcag ggattgggaa ggatgccttt caggaggcag acatcgtggg
      421 aattaccatg ccaatcacta agtacaatta ccaagttcgt gagacagctg atattccgcg
      481 tatcatcacg gaagctgtcc atatcgcaac tacaggccgt ccagggccag ttgtaattga
      541 cctaccaaaa gacatatctg ctttagaaac agacttcatt tattcaccag aagtgaattt
      601 accaagttat cagccgactc ttgagccgaa tgatatgcaa atcaagaaaa tcttgaagca
      661 attgtccaag gctaaaaagc cagtcttgtt agctggtggt ggaattagtt atgctgaggc
      721 tgctacggaa ctaaatgaat ttgcagaacg ctatcaaatt ccagtggtaa ccagtctttt
      781 gggacaagga acgattgcaa cgagtcaccc actctttctt ggaatgggag gcatgcacgg
      841 gtcattcgca gcaaatattg ccatgacgga agcggacttt atgattagta ttggttctcg
      901 tttcgatgac cgtttgacgg ggaatcctaa gactttcgct aagaatgcta aggttgccca
      961 cattgatatt gacccagctg agattggcaa gattatcagt gcagacattc ctgtagttgg
     1021 agatgctaag aaggccttgc aaatgttgct agcagaacca acagttcaca acaatactga
     1081 aaagtggatt gagaaagtca ctaaagacaa gaatcgtgtt cgttcttatg acaagaaaga
     1141 gcgtgtggtt caaccgcaag cagttattga acgaattggt gaattgacga atggagatgc
     1201 cattgtggta acagacgttg gtcaacacca aatgtggaca gctcagtatt atccctacca
     1261 aaatgagcgt cagttagtga cttcaggtgg tttgggaaca atgggctttg gaattccagc
     1321 agcaatcggt gctaaaattg ctaacccaga taaggaagta gtcttgtttg ttggggatgg
     1381 tggtttccaa atgaccaacc aggagttggc tattttgaat atttacaagg tgccaatcaa
     1441 ggtggttatg ctgaacaatc attcacttgg aatggttcgc cagtggcagg aatccttcta
     1501 tgaaggcaga acatcagagt cggtctttga tacccttcct gatttccaat tgatggcgca
     1561 ggcttatggt attaaaaact ataagtttga caatcctgag accttggctc aagaccttga
     1621 agtcatcact gaggatgttc ctatgctaat tgaggtagat atttctcgta aggaacaggt
     1681 gttaccaatg gtaccggctg gtaagagtaa tcatgagatg ttgggggtga agttccatgc
     1741 gtagaatgtt aacagcaaaa ctacaaaatc gttcaggagt cctcaatcgc tttacaggtg
     1801 tcctatctcg tcgtcaggtt aatattgaaa gcatctctgt tggagcaaca gaagatccga
     1861 atgtatcgcg tatcactatt attattgatg ttgcttctca tgatgaagtg gagcaaatca
     1921 tcaaacagct caatcgtcag attgatgtga ttcgcattcg agatattaca gacaagcctc
     1981 atttggagcg cgaggtgatt ttggttaaga tgtcagcgcc agctgagaag agagctgaga
     2041 ttttagcgat tattcaacct ttccgtgcaa cagtggtaga cgtagcgcca agctcgatta
     2101 ccattcagat gacgggaaat gcagaaaaga gcgaagccct attgcgagtc attcgcccat
     2161 acggtattcg caatattgct cgaacgggtg caactggatt tacccgcgat taaaaatcca
     2221 acttaaattt gttaaaccag cttaaaaggc aataaataat agaaaagaga gaaaagctat
     2281 gacagttcaa atggaatatg aaaaagatgt taaagtagca gcacttgacg gtaaaaaaat
     2341 cgccgttatc ggttatggtt cacaagggca tgcgcatgct caaaacttgc gtgattcagg
     2401 tcgtgacgtt attatcggtg tacgtccagg taaatctttt gataaagcaa aagaagatgg
     2461 atttgatact tacacagtaa cagaagctac taagttggct gatgttatca tgatcttggc
     2521 gccagacgaa attcaacaag aattgtacga agcagaaatc gctccaaact tggaagctgg
     2581 aaacgcagtt ggatttgccc atggtttcaa catccacttt gaatttatca aagttcctgc
     2641 ggatgtagat gtcttcatgt gtgctcctaa aggaccagga cacttggtac gtcgtactta
     2701 cgaagaagga tttggtgttc cagctcttta tgcagtatac caagatgcaa caggaaatgc
     2761 taaaaacatt gctatggact ggtgtaaagg tgttggagcg gctcgtgtag gtcttcttga
     2821 aacaacttac aaagaagaaa ctgaagaaga tttgtttggt gaacaagctg tactttgtgg
     2881 tggtttgact gcccttatcg aagcaggttt cgaagtcttg acagaagcag gttacgctcc
     2941 agaattggct tactttgaag ttcttcacga aatgaaattg atcgttgact tgatctacga
     3001 aggtggattc aagaaaatgc gtcaatctat ttcaaacact gctgaatacg gtgactatgt
     3061 atcaggtcca cgtgtaatca ctgaacaagt taaagaaaat atgaaggctg tcttggcaga
     3121 catccaaaat ggtaaatttg caaatgactt tgtaaatgac tataaagctg gacgtccaaa
     3181 attgactgct taccgtgaac aagcagctaa ccttgaaatt gaaaaagttg gtgcagaatt
     3241 gcgtaaagca atgccattcg ttggtaaaaa cgacgatgat gcattcaaaa tctataacta
     3301 attagaaata tatagcgctg gagatgattt tatgaaaaag attatgagaa aaattgcatc
     3361 gttattattg gttctagttg tataatgtaa ttacaccgtc ggtaatagtg ctagcagacc
     3421 aaaataaagc agattggtcg tatgatgaaa atactgtaat taacatttat gatgatgcta
     3481 attttgaaga tggtaggttg catatgacct ttgaacaatt cttcaaattg gcacaaatag
     3541 ctagagaaga aggtcttgaa attcattttc cgtttgagag agctggtgcg actaaatctg
     3601 ctcgttatat agcgaaatgg attttgagaa ataaaaaaca ttaacaaata tagttggtaa
     3661 atcattagga cctaaatcag ctgttagatt cggagaagct ttatcctata ttgaaggtcc
     3721 tcttcgcaga ataaatgaga cgatagatgg cggtttatat caaatagagc aaattattgc
     3781 atctggattg aaagaatcgg gtttaaatga ctggactgcg aaaactttag cttcagctat
     3841 tcgtgggata ttagatgtac ttatttaggg gttgaaatca tatgaatatt accaatttgt
     3901 tttctatcaa gacaggatgt gatgaaactg ataggcaact gcaaaaacta ttttttcagt
     3961 tggatttaca attgggagaa ttgacagatc aactaagaaa attagattct aattttgttc
     4021 ctcgtagtca atttgtagac acgttggatt tgaatgatgt agaatataaa gaaattttaa
     4081 actattttat cttccatcgt aatgatagtg aagaaagttt ggtagaatgg ttatatgatt
     4141 ggatttccac aaatcgttat gaacttccta aagagttttc gattcgtatg gctcataaat
     4201 accatgaaag tgttactgaa gttttcggag atgaataact aaaaaacagt cattagtgac
     4261 tgttttttat agaaaaagag gttttatatg ttaagttcaa aagatataat caaggctcac
     4321 aaggtcttga acggtgtggt tgtgaatact ccactggatt acgatcatta tttatcggag
     4381 aagtatggtg ctaagattta tttgaaaaaa gaaaatgccc agcgtgttcg ctcctttaaa
     4441 attcgtggtg cctattatgc catttcccag ctcagcaagg aagaacgtga acgtggggta
     4501 gtctgcgctt ctgcgggaaa tcatgcgcag ggagtagcct atacttgtaa tgaaatgaaa
     4561 attcctgcta ctatctttat gcccattact acgccacaac aaaagattgg tcaggttcgc
     4621 ttttttggtg gggattttgt aactattaaa ctagttggag atacctttga tgcctcagcc
     4681 aaagcagctc aagaatttac agtctctgaa aatcgtacct ttattgatcc ttttgatgat
     4741 gctcatgttc aagcaggtca aggaacagtt gcttatgaga ttttagaaga agctcgaaaa
     4801 gaatcgattg attttgatgc tgtcttggtt cctgttggtg gtggcggtct cattgccggg
     4861 gtttctacct atatcaagga aacaagtcca gagattgagg ttatcggagt agaggcgaat
     4921 ggagcgcgtt ccatgaaagc tgcctttgag gctggaggtc cagtaaaact caaggaaatt
     4981 gataaatttg ctgatgggat tgctgtgcaa aaggtaggtc agttgaccta tgaagcaact
     5041 cgtcaacata ttaaaacttt ggtaggtgtc gatgagggat tgatttctga aaccttgatt
     5101 gacctttact ctaagcaagg gatagtcgca gaacctgctg gagcggctag tatcgcctct
     5161 ttagaggttt tagctgaata tattaagggg aaaaccattt gttgtatcat ttctggagga
     5221 aataatgata tcaaccgtat gccagaaatg gaagagcgtg ccttgattta tgatggtatc
     5281 aaacattact ttgtggtcaa tttcccacaa cgtccaggag ctttgcgtga gtttgtaaat
     5341 gatatcctgg ggccaaatga tgatatcaca cgttttgagt atatcaaacg agctagcaag
     5401 ggaacaggcc cagtattaat tgggatcgct ttagcagata agcatgatta tgcaggtttg
     5461 attcgtagaa tggaaggttt tgatccagct tatattaact taaatggtaa tgaaacgctt
     5521 tataatatgc ttgtctgagg actaataaaa aaatatcata ttatttgtac aactgatgta
     5581 tatgtgctat aatgaagatg aagaaagggg acgattccta tggttttaga aaacttatcg
     5641 tgcaattctt acttctgttc attatagcac ttatgatgtt tggctcagat ttccatcctt
     5701 cattttgatt tcctatctat tgacaagcat agtcacactg tttttaatac tcttcgaaaa
     5761 tctcttcaaa ccacgttagc tctatctgca acctcaaaac agtgttttga gcaacttgcg
     5821 gctagcttcc tagtttgctc tttgattttc attgagtata aggtatgatt tgatttcttt
     5881 ttgttgacaa atataccata ttaaaaagat atataagtaa ttaactgagc ttatctgtct
     5941 tgtcatctct attaaggatg gtttagataa tcgggtgtct gcttctaggc tagcacctca
     6001 atatccaaag gagtgatgaa tttgaaggac ataaggaata cctatctctc agatgattta
     6061 ttgaggaaga aagataggag tttttgagct agtgaaggct tggatttcta aaggttagaa
     6121 ctatcatctt cagttcttaa atcgaagaaa taagctatct tacggaaata gagaagcatt
     6181 ttttaagaac ttgaataatt tcgcacctta agagggtaat aatacagtat ttttattagc
     6241 aaatatttat ggtgtagagg ctagcaaaac ctatatgtta tcggatttaa aaaggaagta
     6301 agaaaat
//
LOCUS       DAVKMO010000074         5988 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVKMO010000074 DAVKMO010000000
VERSION     DAVKMO010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5988
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.074"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            49..444
                     /locus_tag="VW361_001922"
     CDS             49..444
                     /locus_tag="VW361_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU9744906.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            455..826
                     /locus_tag="VW361_001923"
     CDS             455..826
                     /locus_tag="VW361_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU9744907.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            836..3079
                     /locus_tag="VW361_001924"
     CDS             836..3079
                     /locus_tag="VW361_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9744908.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEAIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLAGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            3286..5061
                     /gene="spxB"
                     /locus_tag="VW361_001925"
     CDS             3286..5061
                     /gene="spxB"
                     /locus_tag="VW361_001925"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU9744909.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            5172..5519
                     /locus_tag="VW361_001926"
     CDS             5172..5519
                     /locus_tag="VW361_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9744910.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(5636..5988)
                     /locus_tag="VW361_001927"
                     /pseudo
     CDS             complement(5636..5988)
                     /locus_tag="VW361_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         1760 a         1132 c         1364 g         1732 t
ORIGIN      
        1 gtatactgtt gagtgtaatt gacaaatgta gattttggag gtatggtaat gcagatttca
       61 gatgcagaat ggcaggtcat gaagattatt tggatgcagg gggagcagac cagtacagat
      121 ttgattaggg ttttggcaga gcggtttgac tggtccaagt ccacggttca gacacttttg
      181 gctcgtctag ttgagaaaga gtgtttgact cggaaaaaag aaggcaagtc ctttgtttat
      241 tcagcgcttt taactctaga ccaaagtcgg gatttacttg tccaagatat caaagacaag
      301 gtttgttccc gtaggattag gaatttgttg gctgacttga ttgtagaatg tgaatttact
      361 cagactgact tggaagactt ggaagctgtg atttcagaga agaaatcaag tgctgtaaca
      421 gaagtaagat gtaattgtat gtaaaggaga cgtcatgtta aatagtattg taaccattat
      481 ttgtattgcc cttatcgcgt ttatcttgtt ttggtttttc aaaaagcctg aaaaatctgg
      541 acaaaaagcc cagcaaaaaa acggatacca agagattcga gtggaagtca tgggaggcta
      601 tactcctgag ttgattgtcc tcaagaaatc agtgccagcc cgcattgtct ttgaccgcaa
      661 ggatccttca ccatgtctgg atcaaattgt ttttccagat tttggtgtac atgcgaacct
      721 gccaatgggg gaagagtatg tagtggaaat cacgcctgaa caggctggag agtttggctt
      781 tgcttgtggt atgaacatga tgcacggcaa gatgattgta gagtaggtgg agactatgac
      841 agaaattgtg aaagcaagct tagaaaatgg cattcaaaaa atccgtatcc gagctgaaaa
      901 aggctatcat ccagcccata tccagcttca aaagggaatt ccagctgaga ttacctttca
      961 tcgtgctact ccttcaaact gttataagga aattctgttt gaagaagaag gtatcttgga
     1021 agcaatcggc gtagatgagg agaaagtcat tcgttttaca cctcaagaat tagggagaca
     1081 tgaattttct tgtggcatga agatgcaaaa gggaagctat atagtcgttg agaagactcg
     1141 aaaatctcta tctctcctgc aacgtttttg gattactagt atctttactg tgcctcttgt
     1201 gattctcatg attgggatgt tggcaggtag cattagtcat caagtcatgc attggggaac
     1261 ctttttagca acaacgccta ttatgttagt tgcgggtaag ccatatatcc agagtgcttg
     1321 ggccagtttt aaaaagcaca atgccaacat ggataccttg gttgcgctgg gaactctagt
     1381 ggcttatttc tatagcctag ttgctctctt tgctggtctc cctgtttact tcgaaagtgc
     1441 tggatttatc ctctttttcg ttcttttggg agcagttttt gaggaaaaaa tgaggaaaaa
     1501 tacgtcccaa gctgtggaga aattactgga cttgcaagct aaaaccgcag aagtcttgag
     1561 tgatgatagt tatgtccaag ttcctttgga acaagtcaag gtaggcgacc tgattcgagt
     1621 gcgtcccggt gaaaagattg ctgttgatgg tgtcgtagta gaaggtgtct ctagtattga
     1681 cgaatccatg gtgacaggtg agagtctgcc tgtggacaag acagttggag atactgtcat
     1741 tggctcaacc atcaatcata gtggaacgct tgtctttaga gcagaaaaag ttggctcaga
     1801 gactgttttg gctcagattg tagattttgt gaagaaagct cagacaagtc gtgcgccgat
     1861 tcaggacttg acggataaga tttcagggat ttttgtccca gtagttgtca ttttaggaat
     1921 catgaccttt tgggtttggt tcgtcttgct cagggatagt gtggtcgtgc ttggagctag
     1981 ctttgtgtcc tctcttctct acggagtggc ggttttgatt atcgcctgtc cttgtgcctt
     2041 gggacttgca acaccgacag cccttatggt ggggacagga cgtagtgcca agatgggggt
     2101 tctcctcaaa aatggaactg tcttacagga aatccagaaa gttcaaactc ttgtctttga
     2161 taagaccggg actttgacgg aagggaaacc tgtggtaaca gatatcatcg gcgacgaagt
     2221 agaagtgttt gggttggcag cctccttgga agatgcttct caacacccac tggctgaggc
     2281 tatcgttaag cgagcgagtg aagctggact tgagtttcaa actgttgaaa attttcagac
     2341 cttgcacggg aaaggtgttt cagggcgaat taatggaaaa caagttttac ttggaaatgc
     2401 taaaatgctg gatggcatgg atatttctaa tacttatcaa gataaactag aagaactaga
     2461 aaaagaagct aagacagttg tgttcttagc tgttgacaat gaaatcaaag gtttgcttgc
     2521 tttgcaagat attcctaagg aaaatgctaa gctagtcatc agtcagctaa aaaaacgtgg
     2581 tctccgaaca gtcatgctga caggagacaa tgctggtgtg gcgcgtgcta ttgcagatca
     2641 aatcggaatt gaagaggtca ttgcaggcgt cttgccagaa gaaaaagccc atgaaatcca
     2701 taaactgcaa cagtcaggta aagtagcctt tgttggtgat gggatcaatg acgctcctgc
     2761 ccttagtgta gcagatgtgg ggattgctat gggagctgga acagatatcg ccatcgagtc
     2821 agcagatttg gtgttgacaa ccaataatct tttaggagtg gtgcgtgcct ttgatatgag
     2881 taagaaaacc tttcatcgaa ttctactcaa tcttttctgg gcttttatct acaatgttgt
     2941 cggaattccg attgcagcag gagtcttttc aggtgttgga ctggctctca acccagaatt
     3001 ggcaggtcta gccatggcct ttagttctgt atctgttctg accagttccc ttctgttaaa
     3061 ttttagtaaa atagactaaa agtaatgact agatttcttt gttataaaac aaaaatgaca
     3121 acaccttcaa aactgtatta gaatagagaa tagagagttt tgagcagatt tttagaaaag
     3181 tcagcataaa tatgatacag tggaatagta aaaatttgga gaacgtttcc aattctatgt
     3241 aatcgtattc tccaagtcta aaaaaattga aggagagtta tcattatgac tcaagggaaa
     3301 attactgcat ctgcagcaat gcttaacgta ttgaaaacat ggggcgtaga tacaatctac
     3361 ggtatcccat caggaacact cagctcattg atggacgctt tggctgaaga caaagatatc
     3421 cgtttcttac aagttcgcca cgaagagaca ggtgctcttg cagcggttat gcaagctaaa
     3481 ttcggcggct caatcggggt tgcagttggt tcaggtggtc caggtgcgac tcacttgatt
     3541 aacggtgttt acgatgcagc tatggataac actccattcc tagcgatcct tggatcacgt
     3601 ccagttaacg aattgaacat ggatgctttc caagagctta accaaaaccc aatgtacaac
     3661 ggtatcgctg tttacaacaa acgtgtagct tacgctgagc aattgccaaa agtaattgac
     3721 gaagcctgcc gtgctgcagt ttctaaaaaa ggtccagctg ttgttgaaat tccagtaaac
     3781 ttcggtttcc aagaaatcga tgaaaactca tactacggtt caggttcata cgaacgctca
     3841 ttcatcgctc ctgctttgaa cgaagttgaa atcgacaaag ctgttgaaat cttgaacaat
     3901 gctgaacgcc cagttatcta tgctggattt ggtggtgtta aagctggtga agtgattact
     3961 gaattgtcac gtaaaatcaa agcaccaatc atcacaactg gtaaaaactt tgaagctttc
     4021 gaatggaact atgaaggttt gacaggttct gcttaccgtg ttggttggaa accagccaac
     4081 gaagtggtct ttgaagcaga cacagttctt ttccttggtt caaacttccc atttgctgaa
     4141 gtttacgaag cattcaagaa cactgaaaaa ttcatccaag tcgatatcga cccttacaaa
     4201 cttggtaaac gtcatgccct tgacgcttca atccttggtg atgctggtca agcagctaaa
     4261 gctatccttg acaaagtaaa cccagttgaa tcaactccat ggtggcgtgc aaacgttaag
     4321 aacaaccaaa actggcgtga ttacatgaac aaactcgaag gtaaaactga gggtgaattg
     4381 caattgtatc aagtttacaa tgcaatcaac aaacatgctg atcaagacgc tatctactca
     4441 atcgacgtag gtaacactac tcaaacatct actcgtcacc ttcacatgac acctaagaat
     4501 atgtggcgta catctccgct ctttgcgaca atgggtattg cccttcctgg tggtatcgct
     4561 gctaagaaag acaatccaga tcgccaagta tggaacatca tgggtgatgg agcattcaac
     4621 atgtgctacc cagacgttat cacaaacgtt caatacgacc ttccagttat caaccttgtc
     4681 ttctcaaatg ctgagtacgg cttcatcaag aacaaatacg aagatacaaa caaacacttg
     4741 tttggtgtag acttcacaaa cgctgactac gctaaaattg cggaagctca aggagctgtt
     4801 ggattcacag ttgaccgtat cgaagacatc gatgcagttg ttgcagaagc tgttaaattg
     4861 aacaaagaag gtaaaactgt tgtcatcgat gctcgcatca ctcaacaccg tccacttcca
     4921 gtagaagtac ttgaattgga tccaaaactt cactcagaag aagctatcaa agccttcaag
     4981 gaaaaatacg aagcagaaga actcgtacca ttccgtctct tcttggaaga agaaggattg
     5041 caatcacgcg caattaaata attcctctcg ccgaaaatca aatatgaaac ttgtagactt
     5101 tattctttga ttttcataga gcagaacttt aaaagatcgg agcaatccgg tctttttatg
     5161 gaggagagta aatgaattta aatcaattag atattatcgt ttcaaatgtt ccccaagtct
     5221 gtgctgactt ggagcatatt ttggataaaa aggcagatta tgctgatgat ggttttgctc
     5281 agtttacgat tggtagtcac tgccttatgt tgtcacaaaa tcatttggtt cctttggaaa
     5341 actttcagtc aggaatcatt attcatatcg aggttgagga tgtagaccag aactacaaac
     5401 ggttgaacga gcttggtata aaggttttac acggaccaac tgtaaccgat tggggaacag
     5461 agtccttatt agttcaagga cctgctggtc tagtgcttga tttttatcgt atgaaatagg
     5521 tcgcgtagtc atttgacgtt aaccttagct atttttaaaa tagaaattga gaatatgaac
     5581 tattgaaaga tcggagcaat ccggtctttt tatataaaga aattgcatat aatactcatc
     5641 tgctttcaaa aagcattcta gtccatctcc gattaacgat ggactttatc acctccttct
     5701 ccagtccttg tatgacatct tggagttgat tcatgacctc ttccaatatg ggcatcaaca
     5761 gctccataac aatagcgaaa ttctcgtata tagtgactat ggatatgtgg acctactcct
     5821 attggagccc aacaagatcc cagtttactg attctaccga aaccagcctc atcttggtac
     5881 atcaagcgaa ccttacgaaa acgtctactg gttttaaagc gctttcttgt cttcttgaat
     5941 tgagatttta tttttagacg cgacaatggt ttgagcgtct gctttctt
//
LOCUS       DAVKMO010000075         5162 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVKMO010000075 DAVKMO010000000
VERSION     DAVKMO010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.075"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            49..942
                     /locus_tag="VW361_001928"
     CDS             49..942
                     /locus_tag="VW361_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HEU9744911.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLGKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NVMYMPIIKTIEELDFVLSFEGINTVAVELVFQDLENPIISKKVIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     NNNKGELSCSKTLKRLHSLLH"
     gene            900..1961
                     /locus_tag="VW361_001929"
     CDS             900..1961
                     /locus_tag="VW361_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9744912.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTGFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNELKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            1978..2982
                     /locus_tag="VW361_001930"
     CDS             1978..2982
                     /locus_tag="VW361_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744913.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSETQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIEEKVTMYINPRDIMQF
                     "
     gene            2994..4688
                     /locus_tag="VW361_001931"
     CDS             2994..4688
                     /locus_tag="VW361_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9744914.1"
                     /translation="MRKSLNWKDCLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEADKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIAAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            4690..>5162
                     /locus_tag="VW361_001932"
     CDS             4690..>5162
                     /locus_tag="VW361_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU9744915.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSS"
BASE COUNT         1760 a          723 c          953 g         1726 t
ORIGIN      
        1 aagaaatcgg atacaatgta attaacaata aagataggag aaaataattt gaatccatta
       61 aaagaatgct atgaaaaaaa cggtatacta attgcagcac accgtggtac aaacggagga
      121 aatatattac aaaacacatc aaaagcctat ttgaattcca tacgccataa cgcagatatg
      181 tttgaggttg atgtaattcg ttcaaaagat ggagaatttt ttgcatttca cgatgggcaa
      241 gaacctttag tatttggtga aaaaattgat attagaactt tgagttctga agagatccaa
      301 agaaaggaat gttttaattc actgaatgaa cccatattac aaaagattga aaaaatttct
      361 gatgtattaa aaaattttga gggacagtct ttaataaata tagatagaag ttggttttac
      421 tgggatacct tcctaggtaa gttaaaaaca tatccatctt tgaatcaagt tcttttaaaa
      481 tcacctgtaa aaaaagaatt attggaaatg cttagagact ctggtttgaa tgttatgtat
      541 atgccaatta tcaaaacaat tgaagagtta gattttgttc tttcatttga aggaataaat
      601 acagtagctg tcgaacttgt attccaagat ttagaaaatc caatcataag taagaaagta
      661 attgatgatt tacatgaaaa aggattactt atttgggtta atgctttaac cttaagtgat
      721 tcaattattc tttcggctaa gattgatgat gatacagcta ttgctcatga tggcgaatct
      781 tgggggaaat tggtttcaat aggatttgat attattcaaa cagattggcc attattactt
      841 tatcaatatc tagttgaaaa aaataaaaaa ataaaaaata ataataaagg agaactatca
      901 tgttcaaaaa ctttaaaaag attgcattca cttcttcact aattttactt gctgcttgct
      961 caaacaatgc ttcaaataca aatcagtcta ctgatgaagg aagtgttgat aaatctcaag
     1021 aaattgtaat ctatacaaat tcggcttcta atggacgtgc agattggtta caaactaaag
     1081 catcagagca aggatacaat ctccgtttgg tagatatttc aggtggagaa ctagctgacc
     1141 gtttgattgc agaaaagaat aatgctgtgg ctgatatggt aattggatta aataaattag
     1201 aatttaaccg tattaaagct gaaaaacttc ttgtaaaata ctcaccaaaa tgggctgatg
     1261 aagtagatag ctctttggga gattctgaag ggtattattc accaattgta aatcaaccat
     1321 tagttttgat tggtaataaa gatgctaaaa tgccatccga ctggacaggt tttactgatt
     1381 catcttataa aggtaaatat ggtatttcaa aattaagtac aggtacatct aagaacatct
     1441 ttgcaagtat tgtttcgaga tataaagatg aaaaaggtga gttaggaata tctgatgaag
     1501 gttggaaagt tgcaaaagct taccttaaaa atgcacacgt ttatgcagaa ggtgaagact
     1561 atatctcttc aattatggat aataataatg agctaaaata tagtatgatg tggggatctg
     1621 gtgttctaca aaatcaaaaa gaacgtgaat ataaattcca agtaatgtca ccaaaagttg
     1681 gtgttcctta tgtaactgaa caagttggga ttttaaatac aagtaagaag caagcattat
     1741 taaaagaatt tgtagattgg tttggctctt cagaacttca aaaagaatgg tctgataaat
     1801 ttggttcaat tccagctaat aaaaaagctc tagagcaagc aaaagatgaa ctcaaacagt
     1861 ttgctaatag tgttaaacca caagaacttg actgggaatt tatcgggaaa aacatcgatt
     1921 cttggattga aaaagcacag cttgaatttg ttgaacaata atagttagga ttaagtgatg
     1981 attacattta aggatattca aattaagtat aatgatttta ttgccatcga taatctcaat
     2041 ttaacaatca atgagggaga gtttttcaca tttttaggac caagtggttg tgggaaatca
     2101 acaactcttc gtgcactagt tggatttttg gagccttcac aggggcaaat actagttgat
     2161 aatcaagata ttacgaattt agatccagaa aaacgcgaaa ttggtattgt gtttcaaagt
     2221 tatgcattat tcccaacaat gactgttttt gataatattg cttttggtct aaaagttaaa
     2281 aaagtttctc ctgaaattat taaagctaaa gttcatgaaa ttgcgaaaaa aattaatatc
     2341 tcagacgagc aactaaaccg aaatatttct gaattatcag ggggacaaca acagcgtgta
     2401 gctttagcac gtgcattagt attagaacca aaaattcttt gtttggatga accgttatca
     2461 aacctagatg ccaaactacg agtttcgttg agaaaagaat tgaaacgatt gcaaaaagaa
     2521 ctaggaatca ctactcttta tgtcacacat gatcaagaag aagcattaac attatcagat
     2581 aggattgctg tgtttaataa tggatttatt gagcaagttg gcacgccgta tgatatttat
     2641 aatcaatccg aaactcaatt tgtctgtgat tttattggct caatcaataa aattagccaa
     2701 gaagttctta aaaaattaca aggcgagaat aaatacttta aagaaactga aggatacata
     2761 cgcttagagc gtgttaagtt agagaaaact tcacctcaag atttatctat aacaggggta
     2821 attagtgata ttgagtttaa tggtgtactt attaagtata aagtagactt gtcgaatagt
     2881 gaaagtattc atattatcga aaagaatgat ggactatcac gtcatataat cgaagaaaaa
     2941 gtcactatgt acattaatcc gcgtgatata atgcaatttt aaggagattg tgcatgagaa
     3001 agagtctaaa ctggaaagat tgtctcataa gattaggagt tttatggcta atctttgccc
     3061 tgattattta tccaaatatt gaacttttgt ctggagtgtt ttataaaaat ggttcattta
     3121 ctctagaggc attcaataag attatacact ctcagagagc gatgagtagt atatttaata
     3181 gctttatttt ggcgatttca atggtcttta ctgtaaatat tgttgggaca ttgattgttc
     3241 tactcacaga gtactgggat attaggggtt caaaaatact taaattaggt tatatgagct
     3301 ctctagtata tggaggaatt gtattagcga caggatataa atttgtttat ggcgctaatg
     3361 gtcttgtaac taaaacgctc tcaagtataa ttccaggtct tgcccctaac tggtttcaag
     3421 gatttggtgc agtattgttt attatgacat ttgcttgtac ctcaaatcac ataatgtttt
     3481 taacaaatgc agttcgtagt gttgattatc atacaattga agcagataaa aatatgggtg
     3541 caagtccttt aaaagttttc tttagtgtgg tttttccaac ttttaaacct acgttatttg
     3601 ccttaaccat cttaactttt ttgacaggtc tttcagcagt ttctgctcct ttgatagtag
     3661 gggggaaaga ttttcaaact attaacccat tgattatcag tttcgctaaa actacaagtt
     3721 cgagagattt agcagcttta ctagctatca tgttaggttt agcaactatt ctattattga
     3781 cacttttgaa tcatgtcgaa aaaggaggta attatgtatc tgtttcgaaa accaaggcta
     3841 gtattaagaa gcagataatt tcttctccat tatggaatac tcttgctcac attgctgcgt
     3901 atgtattgtt tgcaatctat atgttaccaa tagttttgat aattctatac tcgtttacag
     3961 actcgttgac gatcaagacg ggaactttag atctatctaa atttacgtta gcgaactatg
     4021 ctaatttatt tacagatgct caatcatttc gtccttacct agtcagcgtt gtttatgcaa
     4081 ttttagctgc ggtaattgct acaattatag caatagtaat ttcacgtatt gtacataaaa
     4141 acaagagtaa gttcgataaa ttctttgagt atggtgcact gataccatgg atattgccag
     4201 gtacattgat tgcactagga ttaatgttca cttataatat acctcattta atactattta
     4261 atttagtttt agtaggaaca gtaattattt tacttattgc atatactatt caaaaattac
     4321 cattttctta tagaatgatt cgggctgtat ttttcagtat agataatgat atggaagaag
     4381 ctgcacgtag tatgggtgca tctagtttct acactatggt gcgagttatt ataccgtata
     4441 ttttaccagt cgtattatca gtagttgtgt taaactttaa ttctttatta tctgactatg
     4501 acttatctgt attcttgtac catccacttt tccaaccatt gggaatcgtt attaaacagt
     4561 ctactgatga aacagcaact ttaaatgcac aggcaatgat gtttgtttat tctgtaattt
     4621 taatgattat gtctagtgca gctctttatt tatcaagcct attccaaggt aaacgaggta
     4681 agagataata tgaatctttc atacgaactg agtatttggg aaatacttct taggtgcttt
     4741 ttagcgattc ttttcggtgg cattgttggc tatgagcgag gagtcaaaaa ccaagcagca
     4801 gggattagaa cctacttact agtttgtttg ggaacttgtg ttgtaatgat gacaaatcag
     4861 ttcatcacta gtcgttatgg tagcggtgat cctagtcgaa tgggagccca agtaattagt
     4921 ggcttgggtt tcctaggggc aggaacaatc atggtaacta atcaaaaagt taaaggttta
     4981 acaacagcag ctggattatg gtcttcagca actattggtt tagctatagg cattggtttt
     5041 tatgaaggtg ctattttagc cggagttgta ctcatagcag ttttaactct atttactcct
     5101 cttaaagatt atttaaactc gaaaactaaa attgctgatt actacttggt ttttagttct
     5161 tt
//
LOCUS       DAVKMO010000076         4854 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVKMO010000076 DAVKMO010000000
VERSION     DAVKMO010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.076"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            146..1691
                     /locus_tag="VW361_001933"
     rRNA            146..1691
                     /locus_tag="VW361_001933"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1743..1815
                     /locus_tag="VW361_001934"
     tRNA            1743..1815
                     /locus_tag="VW361_001934"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1776..1778,aa:Ala,seq:tgc)
     gene            1940..4841
                     /locus_tag="VW361_001935"
     rRNA            1940..4841
                     /locus_tag="VW361_001935"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1363 a          994 c         1433 g         1064 t
ORIGIN      
        1 tcgcttgaga gaagcaagtg acaaagacct ttgaaaactg aacaagacga accaatgtgc
       61 agggcgctac aacataagtt gtagtactga acaatgaaaa aaacaataaa tctgtcagtg
      121 acagaaatga gtaagaactc aaacttttaa tgagagtttg atcctggctc aggacgaacg
      181 ctggcggcgt gcctaataca tgcaagtaga acgctgaagg aggagcttgc ttctctggat
      241 gagttgcgaa cgggtgagta acgcgtaggt aacctgcctg gtagcggggg ataactattg
      301 gaaacgatag ctaataccgc ataagagtag atgttgcatg acatttgctt aaaaggtgca
      361 cttgcatcac taccagatgg acctgcgttg tattagctag ttggtggggt aacggctcac
      421 caaggcgacg atacatagcc gacctgagag ggtgatcggc cacactggga ctgagacacg
      481 gcccagactc ctacgggagg cagcagtagg gaatcttcgg caatggacgg aagtctgacc
      541 gagcaacgcc gcgtgagtga agaaggtttt cggatcgtaa agctctgttg taagagaaga
      601 acgagtgtga gagtggaaag ttcacactgt gacggtatct taccagaaag ggacggctaa
      661 ctacgtgcca gcagccgcgg taatacgtag gtcccgagcg ttgtccggat ttattgggcg
      721 taaagcgagc gcaggcggtt agataagtct gaagttaaag gctgtggctt aaccatagta
      781 ggctttggaa actgtttaac ttgagtgcaa gaggggagag tggaattcca tgtgtagcgg
      841 tgaaatgcgt agatatatgg aggaacaccg gtggcgaaag cggctctctg gcttgtaact
      901 gacgctgagg ctcgaaagcg tggggagcaa acaggattag ataccctggt agtccacgct
      961 gtaaacgatg agtgctaggt gttagaccct ttccggggtt tagtgccgta gctaacgcat
     1021 taagcactcc gcctggggag tacgaccgca aggttgaaac tcaaaggaat tgacgggggc
     1081 ccgcacaagc ggtggagcat gtggtttaat tcgaagcaac gcgaagaacc ttaccaggtc
     1141 ttgacatccc tctgaccgct ctagagatag agttttcctt cgggacagag gtgacaggtg
     1201 gtgcatggtt gtcgtcagct cgtgtcgtga gatgttgggt taagtcccgc aacgagcgca
     1261 acccctattg ttagttgcca tcatttagtt gggcactcta gcgagactgc cggtaataaa
     1321 ccggaggaag gtggggatga cgtcaaatca tcatgcccct tatgacctgg gctacacacg
     1381 tgctacaatg gctggtacaa cgagtcgcaa gccggtgacg gcaagctaat ctcttaaagc
     1441 cagtctcagt tcggattgta ggctgcaact cgcctacatg aagtcggaat cgctagtaat
     1501 cgcggatcag cacgccgcgg tgaatacgtt cccgggcctt gtacacaccg cccgtcacac
     1561 cacgagagtt tgtaacaccc gaagtcggtg aggtaaccgt aaggagccag ccgcctaagg
     1621 tgggatagat gattggggtg aagtcgtaac aaggtagccg tatcggaagg tgcggctgga
     1681 tcacctcctt tctaaggata aggaactgcg cattggtctt gtttagtctt gagaggtctt
     1741 gtggggcctt agctcagctg ggagagcgcc tgctttgcac gcaggaggtc agcggttcga
     1801 tcccgctagg ctccattggt gagagatcac caagtaatgc acattgaaaa ttgaatatct
     1861 atatcaaata gtaacaagaa aataaaccga aaacgctgta gtattaataa gagtttatga
     1921 ctgaaaggtc agaaaataag gttaagttaa taagggcgca cggtggatgc cttggcacta
     1981 ggagccgacg aaggacgtga caaacgacga tatgccttgg gtagctgtaa gtaagcgatg
     2041 atccagggat ttccgaatgg gggaacccaa caggtaatac ctgttaccca catctgttaa
     2101 ggatgtgagg aggaagacgc agtgaactga aacatctaag tagctgcagg aagagaaagc
     2161 aaaagcgatt gccttagtag cggcgagcga aacggcagaa gggcaaaccg aagagtttac
     2221 tcttcggggt tgtaggactg caatgtggac tcaaagatta tagaagaatg atttgggaag
     2281 atcagccaaa gagagtaata gcctcgtatt taaaatagtc tttgtaccta gcagtatcct
     2341 gagtacggcg ggacacgtga aatcccgtcg gaatctggga ggaccatctc ccaaccctaa
     2401 atactcccta gtgaccgata gtgaaccagt accgtgaggg aaaggtgaaa agcaccccgg
     2461 gaggggagtg aaatagaacc tgaaaccgtg tgcctacaac aagttcgagc ccgttaatgg
     2521 gtgagagcgt gccttttgta gaatgaaccg gcgagttacg ttatgatgcg aggttaagtt
     2581 gaagagacgg agccgtaggg aaaccgagtc tgaatagggc gccttagtat catgacgtag
     2641 acccgaaacc atgtgaccta cccatgagca ggttgaaggt gcggtaagac gcactggagg
     2701 accgaaccag ggcacgttga aaagtgcttg gatgacttgt gggtagcgga gaaattccaa
     2761 acgaacttgg agatagctgg ttctctccga aatagcttta gggctagcgt cgacattaga
     2821 gattcttgga ggtagagcac tgtttgggtg aggggtccat cccggattac caatctcaga
     2881 taaactccga atgccaatga attatggtcg gcagtcagac tgcgagtgct aagatccgta
     2941 gtcgaaaggg aaacagccca gaccaccagc taaggtccca aaataattgt taagtggaaa
     3001 aggatgtggg gttgcacaga caactaggat gttagcttag aagcagctat tcattcaaag
     3061 agtgcgtaat agctcactag tcgagtgacc ctgcgccgaa aatgtaccgg ggctaaaaca
     3121 atttaccgaa gctgtggata cctttatagg tatggtagga gagcgttcta tgtgtgatga
     3181 aggtataccg tgaggagtgc tggaacgcat agaagtgaga atgccggtat gagtagcgaa
     3241 agacaggtga gaatcctgtc caccgtaaga ctaaggtttc caggggaagg ctcgtccgcc
     3301 ctgggttagt cgggacctaa ggagagaccg aaaggtgtat ccgatggaca acaggttgat
     3361 attcctgtac tagagtatgt agtgatggag ggacgcagta ggctaactaa agcagacgat
     3421 tggaagagtc tgtctaagca gtgaggtgtg aattgagtca aatgcttaat tctataacat
     3481 tgagctgtga tggggagcga agtttagtag cgaagttagt gacgtcacac tgccaagaaa
     3541 agcttctagc gtttaaacat actctacccg taccgcaaac cgacacaggt agtcgaggcg
     3601 agtagcctca ggtgagcgag agaactctcg ttaaggaact cggcaaaatg accccgtaac
     3661 ttcgggagaa ggggtgctga ctttaagtca gccgcagtga ataggcccaa gcaactgttt
     3721 atcaaaaaca cagctctctg ctaaatcgta agatgatgta tagggggtga cgcctgcccg
     3781 gtgctggaag gttaagagga gtgcttagcg taagcgaagg tatgaattga agccccagta
     3841 aacggcggcc gtaactataa cggtcctaag gtagcgaaat tccttgtcgg gtaagttccg
     3901 acccgcacga aaggcgtaat gatttgggca ctgtctcaac gagagactcg gtgaaatttt
     3961 agtacctgtg aagatgcagg ttacccgcga caggacggaa agaccccatg gagctttact
     4021 gcagtttgat attgagtgtc tgtaccacat gtacaggata ggtaggagtc taagagatcg
     4081 ggacgccagt ttcgaaggag acgctgttgg gatactaccc ttgtgttatg gccactctaa
     4141 cccagatagg tgatccctat cggagacagt gtctgacggg cagtttgact ggggcggtcg
     4201 cctcctaaaa ggtaacggag gcgcccaaag gttccctcag aatggttgga aatcattcgc
     4261 agagtgtaaa ggtataaggg agcttgactg cgagagctac aactcgagca gggacgaaag
     4321 tcgggcttag tgatccggtg gttccgtatg gaagggccat cgctcaacgg ataaaagcta
     4381 ccctggggat aacaggctta tctcccccaa gagttcacat cgacggggag gtttggcacc
     4441 tcgatgtcgg ctcgtcgcat cctggggctg tagtcggtcc caagggttgg gctgttcgcc
     4501 cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag acagttcggt ccctatccgt
     4561 cgcgggcgta ggaaatttga gaggatctgc tcctagtacg agaggaccag agtggactta
     4621 ccgctggtgt accagttgtc ttgccaaagg catcgctggg tagctatgta gggaagggat
     4681 aaacgctgaa agcatctaag tgtgaaaccc acctcaagat gagatttccc atgattatat
     4741 atcagtaaga gccctgagag atgatcaggt agataggtta gaagtggaag tgtggcgaca
     4801 catgtagcgg actaatacta atagctcgag gacttatcca aagtaactga gaat
//
LOCUS       DAVKMO010000077         4765 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVKMO010000077 DAVKMO010000000
VERSION     DAVKMO010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.077"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            302..1681
                     /locus_tag="VW361_001936"
     CDS             302..1681
                     /locus_tag="VW361_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9744916.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAQTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGCLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIASRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMLLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            1695..2360
                     /locus_tag="VW361_001937"
     CDS             1695..2360
                     /locus_tag="VW361_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU9744917.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            2474..2569
                     /locus_tag="VW361_001938"
                     /pseudo
     CDS             2474..2569
                     /locus_tag="VW361_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2715..3253
                     /locus_tag="VW361_001939"
                     /pseudo
     CDS             2715..3253
                     /locus_tag="VW361_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            3320..3730
                     /locus_tag="VW361_001940"
     CDS             3320..3730
                     /locus_tag="VW361_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU9744918.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQENPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            3846..>4765
                     /gene="pavB"
                     /locus_tag="VW361_001941"
     CDS             3846..>4765
                     /gene="pavB"
                     /locus_tag="VW361_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU9744919.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVK"
BASE COUNT         1341 a          900 c         1072 g         1452 t
ORIGIN      
        1 gacttcgtca gttctatcca caacctcaaa acagtgtttt gagcaacctg tgactagctt
       61 tctaatcgat gccttggttc tcattgccta taatcaaaaa gagaaatttt ctcctgaaaa
      121 gcatatagag tagctggcgt taaaagctcc tgtctcgctt ttttgaccta tagtcacatc
      181 tatcaagtat tgttcttgcc taagctatca ataaaaaggt ggcatttttt aggcttggtg
      241 ttagtagatt ttgccttatc ctatctaagt catttcgaac tttttatggt acaatggaaa
      301 catgttattc aaattatcta aggaaaaaat agagctaggc ttatctcgtt tatcgccagc
      361 ccgtcgtatt tttttgagtt ttgccttggt cattttacta ggctctcttc ttttgagctt
      421 gccctttgtc caagttgaaa gctcacgagc gacttatttt gatcatcttt tcactgctgt
      481 ctctgcagtc tgtgtgacag gtctctcaac ccttccagta gctcaaacct ataatatatg
      541 gggccaaata atctgtttgc ttttgattca gatcggtggt ctagggctca tgacctttat
      601 tggggttttc tatatccaga gcaagcaaaa gcttagtctt cgtagccgtg caactattca
      661 ggatagtttt agttatggag aaactcgatc tttgagaaag tttgtctatt ctatttttct
      721 cacgaccttt ttggttgaga gcttgggagc tattttgctt agttttcgcc ttattcctca
      781 acttggctgg ggacgtggtc tttttagttc catttttcta gcgatctcag ccttctgtaa
      841 tgccggtttt gataatttag ggagcaccag tttatttgct tttcagaccg atttactggt
      901 caatctggtg attgcaggct tgattattac aggctgcctt ggttttatgg tctggtttga
      961 tttggctggt catgtaggaa gaaagaaaaa aggacgtctg cactttcata cgaagcttgt
     1021 actattgttg actataggtt tgttgttatt tggaacggca actactctct ttcttgagtg
     1081 gaacaatgct ggaacgattg gcaatctccc tgttgccgat aaggttttag ttagcttttt
     1141 tcaaacagtg acgatgcgaa cagctggctt ttctacgata gattatactc aggctcatcc
     1201 tgtgactctt ttgatttata tcttacagat gtttctaggt ggggcacctg gaggaacagc
     1261 tgggggactc aagattacga cattttttgt cctcttggtc tttgcacgaa gtgagcttct
     1321 aggcttgcct catgccaatg ttgcgagacg aacgattgcg tcgcgaacgg ttcaaaaatc
     1381 ctttagtgtc tttattatct ttttgatgag cttcttgata ggattgattc tgctagggat
     1441 aacagccaaa ggcaatcctc cctttatcca cctcatattt gaaaccattt cagctcttag
     1501 tacagttggt gtaacggcaa atctgactcc tgaccttggg aaattggctc tcagtgttat
     1561 catgctactt atgtttatgg gacgaattgg tcccttgacc ttgtttgtta gcttggcaga
     1621 ttaccatcca gaaaagaaag atatgattca ctatatgaaa gcagatatta gtattggtta
     1681 agaaaggaaa gagcatgtca gatcgtacga ttggaatttt gggcttggga atttttggga
     1741 gcagtgtcct agctgcccta gccaagcagg atatgaatat tatcgctatt gatgaccacg
     1801 cagagcgcat caatcagttt gagccagttt tggcgcgtgg agtgattggt gacatcacag
     1861 atgaagaatt attgagatca gcagggattg atacctgcga taccgttgta gtcgcgacag
     1921 gtgaaaatct ggagtcgagt gtgcttgcgg ttatgcactg taagagtttg ggggtaccga
     1981 ctgttattgc taaggtcaaa agtcagaccg ctaagaaagt gctagaaaag attggagctg
     2041 actcggttat ctcgccagag tatgaaatgg ggcagtctct agcacagacc attcttttcc
     2101 ataatagtgt tgatgtcttt cagttggata aaaatgtgtc tatcgtggag atgaaaattc
     2161 ctcagtcttg ggcaggtcaa agtctgagta aattagacct ccgtggcaaa tacaatctga
     2221 atattttggg tttccgagag caggaaaatt ccccattgga tgttgaattt ggaccagatg
     2281 acctcttgaa agcagatacc tatattttgg cagtcatcaa caaccagtat ttggataccc
     2341 tagtagcatt gaattcgtaa agagggatga cccctctttt ttgatgccca agatggcaaa
     2401 tagagacaga agccccttgt cttctagtaa aagttcttca aaggctggac tttatggtaa
     2461 aatagaagga agtgacaaga gagagtaata ctcaatgaaa atcaaagatc aaactaggaa
     2521 actagctgcg ggctgctcaa aacactgttt tgaggttgtg gatagaactg acgaagtcag
     2581 ctcaaaacac tgttttgagg ttgcagatag aactgacgaa gtcagtaaca tctatacggc
     2641 aaggcgacgt tgacgcggtt tgaagagatt ttcgaagagt ataagaaaaa atcagtcccc
     2701 taaaggagca gattatgaag ttattgtcta tcgccatttc tagctataat gcagcagcct
     2761 atcttcatta ctgtgtggag tcgctagtga ttggtggtga gcaagttggg attttgatta
     2821 tcaatgacgg gtctcaggac cagactcagg aaatcgctga gtgtttagct agcaagtatc
     2881 ctaatatcgt tagagccatc tatcaggaaa ataaaggcca tggcggtgtg gtcaatcgcg
     2941 gcttggcaga ggcttctggg cgctatttta aagtagttga cagtgatgac tggtggatcc
     3001 tcgtgcctac ttgaaaattc ttgaaacctt gcaggaactt gagagcaagg gtcaagagat
     3061 ggatgtcttt gtgaccaatt ttgtctatga aaaggaaggt cagtctcgta agaagagtat
     3121 gagttacgag tcagtcttgc ctgttcggca gatttttggc tgggaccagg tcggaaattt
     3181 ctccaaaggc cagtatatca tgatgcactc gctgatttat cggacagatt tgttgcgtgc
     3241 tagccagttc taactgcctg aacatacttt ttatgtcgat aatctctttg tctttacgcc
     3301 ccttcagcag gtcaagacca tgtactatct gcctgtcgat ttctatcgtt acttgattgg
     3361 gcgtgaggac cagtctgtca atgagcaagt gatgattaag tgcattgacc agcaactcaa
     3421 ggtcaatcga ctcttggtag accagcttga tttgtcccaa gtgagtcatc ccaaaatgcg
     3481 agaatatctg ctgaatcata ttgaaatcac gacggtgatt tccagtaccc tgctcaaccg
     3541 atctgaaaca gcggagcatc tggcaaaaaa acgccaattg tggacctata ttcagcagga
     3601 aaatccagaa gtctttcagg ctattcgtaa gaccatgttg agccgtttga ccaaacattc
     3661 tgtcttgcca gatcgcaaac tgtccaatgt cgtctatcaa atcaccaaat ctgtttatgg
     3721 atttaattaa tataagtgtt ttataagagg gatttaagaa aaattttaac tttttcttag
     3781 tcctttttaa tttcaggaga ttatactaga gtcatcaaat aaagaaagac tctaaggaga
     3841 atcctatgaa attcaatcca aatcaaagat atactcgttg gtctattcgc cgtctcagtg
     3901 tcggtgttgc ctcagttgtt gtggctagtg gcttctttgt cctagttggt cagccaagtt
     3961 ctgtacgtgc cgatgtggtc aatccgaccc caggtcaagt cttacctgaa gagacatcgg
     4021 gaacgaaaga gggtgactta tcagaaaaac caggagacac cgttctcact caagcgaaac
     4081 ctgagggcgt tactggaaat acgaattcac ttccgacacc tacagaaaga actgaagtga
     4141 gcgaggaaac aaactcttct agtctggata cactttttga aaaagatgaa gaagctcaaa
     4201 aaaatccaga gctaacagat gtcttaaaag aaactgtaga tacagctgat gtggatggga
     4261 cacaagcaag tccagcagaa actactcctg aacaagtaaa aggtggagtg aaagaaaata
     4321 caaaagacag catcgatgtt cctgctgctt atcttgaaaa agctgaaggg aaaggtcctt
     4381 tcactgccgg tgtaaaccaa gtaattcctt atgaactatt cgctggtgat ggtatgttaa
     4441 ctcgtctatt actaaaagct tcggataatg ctccttggtc tgacaatggt actgctaaaa
     4501 atcctgcttt acctcctctt gaaggattaa caaaagggaa atacttctat gaagtagact
     4561 taaatggcaa tactgttggt aaacaaggtc aagctttaat tgatcaactt cgagctaatg
     4621 gtactcaaac ttataaagct actgttaaag tttacggaaa taaagacggt aaagctgact
     4681 tgactaatct agttgctact aaaaatgtag acatcaacat caatggatta gttgctaaag
     4741 aaactgtcga aaaagctgtt aaaga
//
LOCUS       DAVKMO010000078         4427 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVKMO010000078 DAVKMO010000000
VERSION     DAVKMO010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4427
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.078"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..488
                     /locus_tag="VW361_001942"
                     /pseudo
     CDS             1..488
                     /locus_tag="VW361_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            416..868
                     /locus_tag="VW361_001943"
     CDS             416..868
                     /locus_tag="VW361_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744920.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            1700..2059
                     /locus_tag="VW361_001944"
     CDS             1700..2059
                     /locus_tag="VW361_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744921.1"
                     /translation="MGQEIKLIRKQFRITRQEEKQIKEMMREQKVDSFSEFLRQNLLK
                     KNYQDRIFESWFSLWQSQKFEQISRDVYEVLVVARENHQVTQEHVSILLTCVQELIAE
                     VNQVQPLSREFREKYMG"
     gene            2069..2434
                     /gene="mobC"
                     /locus_tag="VW361_001945"
                     /pseudo
     CDS             2069..2434
                     /gene="mobC"
                     /locus_tag="VW361_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
     gene            2421..4271
                     /locus_tag="VW361_001946"
     CDS             2421..4271
                     /locus_tag="VW361_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU9744922.1"
                     /translation="MVVTKHFAIHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSHAEMVEIYNVNFSNNDKLYESRNDRQEKHQQNIHAHHLIQSFSPEDNLTPKEINR
                     IGYETIMELTGGRFRFIVATHTDKDHIHNHILINAIDCNSDKKLIWNYALERNLRMIS
                     DRISKMAGAKIIEKRFSYRDYQEYRATSHKFELKQRLYFLMQQSKSFDDFLEKAEQLH
                     VHIDFSQKHSRFMMTDRAMTKPIRGRQLSKRDLYDEDFFRMHFAKQEIASRLEFLLNC
                     VNSLEGLLTKSKELNLTIDLKQKNVIFILEENGKQFSLSHKKISDEKLYDVNFFQDYF
                     KNKEVGVSEGIENLQAQYRAFQEERDKEKVSTEEIEEAFETFKEKRDAVHEFEVKLTE
                     HQIEKLVDEGIYIKVSFGINQSGLIFIPNYQLDIMEEDNHKKYKVYIRETSSYFVYNK
                     ENRDNNCFIKGRTLIRQLSNDSQKLPYRRPTLKSLQEKISEINLMIELSNTNKQYQEI
                     KDELVLEIAEIDMKLEETQEKIATLNKMAEVLINLKSEDEIGRKLARYDFSKLNLTES
                     TSLENVNEEIRVLQENLDYYLYEFEKRAIRLEIFVSTLNMEKDVFVIDKF"
BASE COUNT         1643 a          633 c          860 g         1291 t
ORIGIN      
        1 agcagaggca atcataaaaa atggaataga aatagttgta gtaactgatc ataatactac
       61 caaaggtatt aaaaagttac aaatggcagt ctcaatcata atgaaaaatt atccgattta
      121 tgatatacat cctcatattt tacatggagt agaaattagt gcagcagata aattgcatat
      181 tgtatgtata tatgattatg aacaagaatc atgggttaat caatggttaa gtgaaaatat
      241 tataagtgag aaagatggaa gttatcaaca ttcactgact ataatgaagg atttcaataa
      301 tcaaaaaata gttaactata ttgctcattt caatagttat gacattttga aaaaaggttc
      361 tcacttatta ggtgcatata aacgaaaaat tttttctaaa gaaaatacac gatttttgga
      421 gtttaatatt aactcgaaag aatcttcgca acaacttgat attctctata aagaagttgg
      481 tgtattaagt ttgggacaaa aagttgtagc catgcttgat tttttattag catatagtga
      541 ctattctaaa gacttcagac cattgattat tgatcagcct gaagacaatc tagacaatcg
      601 ttatatttac aggcatttag ttcagcagtt tagagatgtg aaagctcaac gtcaaattat
      661 tttagcaaca cataatgcta caattgtaac aaattctatg acagatcaag ttgttattat
      721 ggagtcagat ggagttaacg gatggattga atcacaggga tatgttagtg aaaaatatat
      781 aaaaaatcat atcatcaatc aattagaggg aggaaaagat tccttcaagc ataaaatgtc
      841 tatatatgag acggctttat cagagtagag tcagaaaaag taggctagaa atttagccta
      901 cttttttctt tgtccgacag gcatagtgta catctgaggt ccaagtcctc tgtggatatt
      961 tgctgcagat gaaaccaata gcgactccta atcctgaata tcgtgaggta ggggggatag
     1021 gaaggaatta gcgaaatcaa ggctctacaa acagaatcgt gacttgaagc catatatagc
     1081 ggatgaggaa ctctaaaatc caaataggtg tcgtaaccta tatacgtgaa ttacgagagt
     1141 aaactaggaa agatgtacgg cttattccgt gagcgtttag gacgtagtac aacgaatcat
     1201 gggagtcagc tgaacacata gtattgaaga aatttctgta atggaaatgg agcgaagaag
     1261 tgaacaatta aatgaatacc tctctaatta aatttgtcaa ttctaattcc tggtatgaaa
     1321 agacagtgac ctgaaaatgt aaatgatggg agctgatcat aaatatagga cgatacatgc
     1381 agtagtgtta gagattagtc cctacttgat ttgtgataac ttccccaaat ttcttctgct
     1441 atacttttct caacttttaa aaatccaact aagaatttta cctgggtgtt tgggggcgga
     1501 gccaccaagt tatcttatgg ttagctgtca aaactagaag gttttgatag gctggcgata
     1561 tgatttttgg gatattgtgt ccacaatatc tgagctcgca aagaccgaac aaggagagac
     1621 tgaggtcttt aggaatcgta ctgacaatgt gaggcagcct tacactgtca gacaagttga
     1681 atgttgaagg aatatcagaa tgggacaaga aattaagtta atccgtaagc aatttagaat
     1741 cacgagacaa gaagaaaaac agataaaaga aatgatgagg gaacaaaaag tggatagttt
     1801 ctcagaattt cttcgtcaaa atttattgaa aaagaattat caggatagaa tttttgaaag
     1861 ttggttctcc ctttggcagt ctcaaaagtt tgaacagatt agtcgagatg tgtatgaagt
     1921 tctggttgtc gcaagagaaa atcatcaagt gactcaagag cacgtctcaa tcttattgac
     1981 ttgcgttcaa gaattgattg cagaagtgaa tcaagtacag ccactcagtc gtgagtttcg
     2041 tgaaaaatat atgggttagg aggatgtaat ggtttatcgc tatcgtacca atctcaaaaa
     2101 agtatttcta actgatccag aattgaatta attaaatgat cgtattacta agagtcactg
     2161 tcaaaatttc tcagtctacg ccagaaaagt gttacttaat cctaatatgg cttttgtcac
     2221 aattaacacg gatacctatg aacagttagt atttgaattg agacggattg gaaataatat
     2281 taatcaaatt gcgcgcgcta tcaatcagag ccatctgatt tctcaggacc aattacaaga
     2341 attgagtaag ggaattagtg agttaattac tggagtagag aaagattttc aagttgaagt
     2401 gaatagactg aaggagtttt atggtagtca ctaaacattt tgcgatacat ggtaaaaaat
     2461 atcgtaggcg tttaattaag tatattctca accctgataa aacggacaat ttgaaattgg
     2521 tatctgattt tggcatgagc aattacttgg acttccctag tcatgcagaa atggtagaga
     2581 tatacaatgt caacttcagc aataatgaca agttgtacga atccagaaac gaccgacagg
     2641 aaaaacacca acaaaatatt catgctcatc accttattca atcattttct cctgaggata
     2701 atttaacacc aaaagaaatc aatcggattg gttatgagac cattatggaa ttaacaggag
     2761 gccgttttcg tttcatcgta gcgactcata cagacaaaga tcatattcat aatcacatct
     2821 taatcaacgc cattgactgt aattcagata aaaagttgat atggaattat gccttggaac
     2881 gaaaccttcg tatgatttca gaccgcattt ctaaaatggc tggggcgaaa attattgaaa
     2941 agcgtttctc ttaccgtgac tatcaagaat atagagcgac tagccataag tttgaactaa
     3001 agcaacgtct ttattttttg atgcagcagt caaaatcctt tgatgatttt ttagaaaaag
     3061 cagagcaatt acatgttcat attgatttta gtcagaagca tagtcgattc atgatgacgg
     3121 atcgggcaat gacaaaacca attcgaggac gtcaactcag taaacgagat ttatatgatg
     3181 aagatttttt tagaatgcat tttgccaagc aagagattgc aagtcgttta gaatttttgt
     3241 tgaactgtgt caattcttta gaagggttac taacaaaatc aaaagaattg aatctaacca
     3301 ttgacttaaa acaaaaaaat gtaatcttta tacttgaaga aaatggaaag caattcagtc
     3361 tgagtcataa aaaaataagt gatgagaaat tatatgatgt caattttttt caagattatt
     3421 ttaaaaataa ggaagtaggt gtttcagaag gaatagaaaa tctacaggca cagtaccgtg
     3481 cttttcaaga agaacgagat aaggagaagg tatctactga agaaattgag gaagcctttg
     3541 agacatttaa ggaaaaacga gatgccgttc atgaatttga agtaaaactt acagaacacc
     3601 aaattgagaa gttagttgat gaggggattt atatcaaagt gtcctttggt ataaatcaga
     3661 gtggtcttat tttcattcct aactatcaac tggatattat ggaagaagac aatcataaaa
     3721 aatataaagt ctacattcga gaaacgtctt cttactttgt ctataataaa gaaaacaggg
     3781 ataataattg tttcatcaag ggtaggacct taatcagaca attgagcaac gatagccaaa
     3841 aactccccta tagacgacca actttaaaaa gtcttcaaga gaagatttct gaaattaatc
     3901 ttatgattga actatctaac acgaacaaac aataccaaga aatcaaagat gagcttgtgt
     3961 tagaaattgc agagattgat atgaagctag aagaaaccca agaaaaaatc gccaccttaa
     4021 acaaaatggc ggaagtgctt atcaatctga agagtgaaga tgagatcggt agaaaattag
     4081 ccaggtatga cttttcaaaa ctgaacttaa cagaatcaac ttcattagaa aatgtgaacg
     4141 aagaaataag agtattgcaa gaaaacttag actattatct ttatgagttt gagaaaagag
     4201 caataagatt agaaattttt gtaagcacgt taaatatgga aaaagatgtt ttcgtaattg
     4261 acaaatttta gaggagggat aaagctagaa atgctggatt atgcttgatt taaggaactg
     4321 caatacatgg agcacactca tatggtttaa gcacaaataa tttttgacaa taggattaaa
     4381 aaattgtaaa ataaaaatag aagcgctttc ttttgcaaat attagaa
//
LOCUS       DAVKMO010000079         4203 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVKMO010000079 DAVKMO010000000
VERSION     DAVKMO010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4203
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.079"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            713..1705
                     /locus_tag="VW361_001947"
     CDS             713..1705
                     /locus_tag="VW361_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9744923.1"
                     /translation="MAMIEVEHLQKHFVKIVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="VW361_001948"
     CDS             1707..2525
                     /locus_tag="VW361_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU9744924.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="VW361_001949"
     CDS             2527..3312
                     /locus_tag="VW361_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9744925.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLIFFVISLKLWDKGLDSYESAGS"
     gene            3351..3629
                     /locus_tag="VW361_001950"
     CDS             3351..3629
                     /locus_tag="VW361_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU9744926.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3566..3811
                     /locus_tag="VW361_001951"
     CDS             3566..3811
                     /locus_tag="VW361_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744927.1"
                     /translation="MSRRKKAYQGRKIGSQLFATLESEARKKVGYLQVKTVAEGSNKD
                     YDRTNDFYRGFGFKKLEIFLQLWNPQNPCQILIKKLE"
BASE COUNT         1167 a          721 c          909 g         1406 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattaatatc tgattacaaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttacaaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 tggtttaggt agtcggtgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 agggagtatc cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttca tgagagaaat
      541 cctaatttca caatccatag gcaaacgctt gcattctgtt ttttattgga ctataatagg
      601 ttggtataaa gccttctgta gtaataaaat gtagaaggtg tagaaagtaa ggatttagaa
      661 tatttgtagt taaaaacaca atgttgctat tccttatgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaacattt tgtgaagatt gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccagg acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccag actcgctctt tcataagcgt atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcggact ctttcactgg gacaacggat
     1201 gcgggcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcacgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaagagatt tttgatggaa cagtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 gtctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattgtg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatgtcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtca
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattctt tccaaaggtt gtttcagata
     2341 ttctctcctt tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagttg atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtgga ttttgtggtt ggtgtcttgg gagtctttct ggctcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggctggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaagggga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaatttct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct
     3241 ctgattttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa ggaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa aggcagttgt cgctgaggtt ttgaaggatt
     3421 tgccagaatg gtttggaatc ccagaaagca cacaagccta tatagaagga accacgacac
     3481 tgcaagtttg gaccgcctat caggagagtg atttgactgg atttgtaagc ttatcctatt
     3541 cgagtgaaga ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa
     3601 aattgggagc caattgtttg ctactttaga gagtgaagct cgtaaaaaag ttggttatct
     3661 gcaggtcaaa acagtggcag aaggttctaa taaagattat gatcgaacaa atgactttta
     3721 tcgaggtttt ggctttaaaa agttagagat ttttcttcaa ctatggaatc cgcaaaatcc
     3781 ttgtcagatt ttgattaaaa agcttgaata atattatttg acatctattc tcagagtgct
     3841 atactgtaag tgtaatcgcc gatttagctc agttggtaga gcaaggcact cgtaaagcct
     3901 aggttatagg tagataaacg actgaggagt tgaaaaaata gataggtaga agataaccgt
     3961 taagccttat tcttagcggt tatttatatt gtttaatagc gctgatattt catcaattat
     4021 gcctgttttc gtgtttctgg tagttgttca agtttattgc tactattttt gatggtatga
     4081 atgtgcttat aatgtatccc ggttaacgaa agttttggac ttatactctt agaaaatctc
     4141 ttcaaaccac gtcaacgtcg ccttgccgtg cgtatggtta ctgacttcgt cagttctatc
     4201 cac
//
LOCUS       DAVKMO010000080         4058 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVKMO010000080 DAVKMO010000000
VERSION     DAVKMO010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4058
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.080"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..667
                     /locus_tag="VW361_001952"
     CDS             <1..667
                     /locus_tag="VW361_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEU9744928.1"
                     /translation="KVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYE
                     APKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVRKNKADQDSKPDEDKGHDEV
                     SEPTHPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAK
                     IADAEALLEKVTDPSIRQNAMETLTGLKSSLLLGTKDNNTISAEVDSLLALLKKSQPA
                     PIQ"
     gene            877..3996
                     /gene="phtE"
                     /locus_tag="VW361_001953"
     CDS             877..3996
                     /gene="phtE"
                     /locus_tag="VW361_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU9744929.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKIDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEEVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQQSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1503 a          670 c          799 g         1086 t
ORIGIN      
        1 gaaggtgcca cttgatcgta tgccttacaa tcttcaatat actgtagaag tcaaaaacgg
       61 tagtttaatc atacctcatt atgaccatta ccataacatc aaatttgagt ggtttgacga
      121 aggcctttat gaggcaccta aggggtatac tcttgaggat cttttggcga ctgtcaagta
      181 ctatgtcgaa catccaaacg aacgtccgca ttcagataat ggttttggta acgctagcga
      241 ccatgttcgt aaaaataagg cagaccaaga tagtaaacct gatgaagata agggacatga
      301 tgaagtaagt gagccaactc accctgaatc tgatgaaaaa gagaatcacg ctggtttaaa
      361 tccttcagca gataatcttt ataaaccaag cactgatacg gaagagacag aggaagaagc
      421 tgaagatact acagatgagg ctgaaattcc tcaagtagag cattctgtta ttaacgctaa
      481 gatagcagat gcggaggcct tgctagaaaa agtaacagat cctagtatta gacaaaatgc
      541 tatggagaca ttgactggtc taaaaagtag tcttcttctc ggaacgaaag ataataacac
      601 tatttcagca gaagtagata gtctcttggc tttgttaaaa aaaagtcaac cggctccgat
      661 acagtagtaa aatgaatgga gcatatttta tggagaagta acctttcgtg ttacttctct
      721 tttttagaaa aatgtaacag aaacttgaca aaagtaattt taaatagtaa actatttact
      781 ggttaattaa atggttaaat aaccggttta gaaaactatt taataaagta aaagaagttg
      841 agaaaaaact tcatcattta ttgaaatgag ggatttatga aatttagtaa aaaatatata
      901 gcagctggat cagctgttat cgtatccttg agtctatgtg cctatgcact aaatcagcat
      961 cgttcgcagg aaaataagga caataatcgt gtctcttatg tggatggcag ccagtcaagt
     1021 cagaaaagtg aaaacttgac accagaccag gttagccaga aagaaggaat tcaggctgag
     1081 caaattgtaa tcaaaattac agatcagggc tatgtaacgt cacacggtga ccactatcat
     1141 tactataatg ggaaagttcc ttatgatgcc ctctttagtg aagaactctt gatgaaggat
     1201 ccaaactatc aacttaaaga cgctgatatt gtcaatgaag tcaagggtgg ttatatcatc
     1261 aagatcgatg gaaaatatta tgtctacctg aaagatgcag ctcatgctga taatgttcga
     1321 actaaagatg aaatcaatcg tcaaaaacaa gaacatgtca aagataatga ggaggttaac
     1381 tctaatgttg ctgtagcaag gtctcaggga cgatatacga caaatgatgg ttatgtcttt
     1441 aatccagctg atattatcga agatacgggt aatgcttata tcgttcctca tggaggtcac
     1501 tatcactaca ttcccaaaag cgatttatct gctagtgaat tagcagcagc taaagcacat
     1561 ctggctggaa aaaatatgca acagagtcag ttaagctatt cttcaacagc tagtgacaat
     1621 aacacgcaat ctgtagcaaa aggatcaact agcaagccag caaataaatc tgaaaatctc
     1681 cagagtcttt tgaaggaact ctatgattca cctagcgccc aacgttacag tgaatcagat
     1741 ggcctggtct ttgaccctgc taagattatc agtcgtacac caaatggagt tgcgattccg
     1801 catggcgacc attaccactt tattccttac agcaagcttt ctgccttaga agaaaagatt
     1861 gccagaatgg tgcctatcag tggaactggt tctacagttt ctacaaatgc aaaacctaat
     1921 gaagtagtgt ctagtctagg cagtctttca agcaatcctt cttctttaac gacaagtaag
     1981 gagctctctt cagcatctga tggttatatt tttaatccaa aagatatcgt tgaagaaacg
     2041 gctacagctt atattgtaag acatggtgat catttccatt acattccaaa atcaaatcaa
     2101 attgggcaac cgactcttcc aaacaatagt ctagcaacac cttctccatc tcttccaatc
     2161 aatccaggaa cttcacatga gaaacatgaa gaagatggat acggatttga tgctaatcgt
     2221 attatcgctg aagatgaatc aggttttgtc atgagtcacg gagaccacaa tcattatttc
     2281 ttcaagaagg acttgacaga agagcaaatt aaggctgcgc aaaaacattt agaggaagtt
     2341 aaaactagtc ataatggatt agattctttg tcatctcatg aacaggatta tccaagtaat
     2401 gccaaagaaa tgaaagattt agataaaaaa atcgaagaaa aaattgctgg cattatgaaa
     2461 caatatggtg tcaaacgtga aagtattgtc gtgaataaag aaaaaaatgc gattatttat
     2521 ccgcatggag atcaccatca tgcagatccg attgatgaac ataaaccggt tggaattggt
     2581 cattctcaca gtaactatga actgtttaaa cccgaagaag gagttgctaa aaaagaaggg
     2641 aataaagttt atactggaga agaattaacg aatgttgtta atttgttaaa aaatagtacg
     2701 tttaataatc aaaactttac tctagccaat ggtcaaaaac gcgtttcttt tagttttccg
     2761 cctgaattgg agaaaaaatt aggtatcaat atgctagtaa aattaataac accagatgga
     2821 aaagtattgg agaaagtatc tggtaaagta tttggagaag gagtagggaa tattgcaaac
     2881 tttgaattag atcaacctta tttaccagga caaacattta agtatactat cgcttcaaaa
     2941 gattatccag aagtaagtta tgatggtaca tttacagttc caacctcttt agcttacaaa
     3001 atggccagtc aaacgatttt ctatcctttc catgcagggg atacttattt aagagtgaac
     3061 cctcaatttg cagtgcctaa aggaactgat gctttagtca gagtgtttga tgaatttcat
     3121 ggaaatgctt atttagaaaa taactataaa gttggtgaaa ttaaattacc gattccgaaa
     3181 ttaaaccaag gaacaaccag aacggccgga aataaaattc ctgtaacctt catggcaaat
     3241 gcttatttgg acaatcaatc gacttatatt gtggaagtac ctatcttgga aaaagaaaat
     3301 caaactgata aaccaagtat tctaccacaa tttaaaagga ataaagcaca agaaaactca
     3361 aaacttgatg aaaaggtaga agaaccaaag actagtgaga aggtagaaaa agaaaaactt
     3421 tctgaaactg ggaatagtac tagtaattca acgttagaag aagttcctac agtggatcct
     3481 gtacaagaaa aagtagcaaa atttgctgaa agttatggga tgaagctaga aaatgtcttg
     3541 tttaatatgg acggaacaat tgaattatat ttaccatcgg gagaagtcat taaaaagaat
     3601 atggcagatt ttacaggaga agcacctcaa ggaaatggtg aaaataaacc atctgaaaat
     3661 ggaaaagtat ctactggaac agttgagaac caaccaacag aaaataaacc agcagattct
     3721 ttaccagagg caccaaacga aaaacctgta aaaccagaaa actcaacgga taatggaatg
     3781 ttgaatccag aagggaatgt ggggagtgac cctatgttag atccagcatt agaggaagct
     3841 ccagcagtag atcctgtaca agaaaaatta gaaaaattta cagctagtta cggattaggt
     3901 ttagatagtg ttatattcaa tatggatgga acgattgaat taagattgcc aagtggagaa
     3961 gtgataaaaa agaatttatc tgatctcata gcgtaaggaa tagcagtaga aaaagtctga
     4021 atcaaaaatg aagttctctc aaaagttaga aataaaac
//
LOCUS       DAVKMO010000081         3991 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVKMO010000081 DAVKMO010000000
VERSION     DAVKMO010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.081"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(297..1523)
                     /locus_tag="VW361_001954"
     CDS             complement(297..1523)
                     /locus_tag="VW361_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9744930.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLVSDTLSAFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1595..2260)
                     /locus_tag="VW361_001955"
     CDS             complement(1595..2260)
                     /locus_tag="VW361_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9744931.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2328..2525)
                     /locus_tag="VW361_001956"
     CDS             complement(2328..2525)
                     /locus_tag="VW361_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEU9744932.1"
                     /translation="MLNLQFAETMELTEAELETVYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            complement(2816..3680)
                     /locus_tag="VW361_001957"
                     /pseudo
     CDS             complement(2816..3680)
                     /locus_tag="VW361_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
BASE COUNT         1393 a          760 c          724 g         1114 t
ORIGIN      
        1 aacatatata cggcaaagtg aagctgacgt ggtttgaaga gagtttcgaa gagtataagt
       61 aggctgaaaa gaatccagcc acagcatgga ctattatata gcagattgaa ataagatgag
      121 aacaaatcga ttgggaaagt aaaattaatt tctataaatg ttttagcaat tgtttcgtac
      181 tattttagat tcagtctatt ataacacatt cagaaaagag aaaaaagtct gttgattttg
      241 accatcataa aaagactggc aatccagtct caaacatata ttatagaaat tctccactaa
      301 atactttcac gaatattcag aagcatgaca aaggcaacta gaagaaatag caataaaaca
      361 aagctaactg ccagagttcc aaagctagta gcaatggtta ccaaagctat tgtaaataag
      421 ctaggtaaaa caaccgtaat ggcactgata gaagattgaa ctgctcccat tgactcctca
      481 ggtatttgtt taaaaacgag ttcttgcaat ctaggagaga gaacacctgc gaaaaaggca
      541 tccaaggtac taaagatgag aatccagtca aaacgaactg tggcaaatcc tactagaaga
      601 agcaactgga tgacaagtga ggcatagaga gctgttttta tggaaatggt atgttgcaga
      661 tagccactta caaggcttcc gacaatcagg gctgacagtt caaaagtgga tagcaaggca
      721 agagattgac ctgtttgtaa attcaaaaag ggttgattcc tcaaaaatag agtagagaca
      781 ggaaccgtaa catttatcac tgcttgacta gtagagataa taaacaaaac caagagcacc
      841 ttattcatat tccatatcaa tttcgatgat tggagcaaat gctggcaaaa ggattttaca
      901 gagagtcctt cttgatagct aatcgttttt tctactttca agaggtcagt ttttatgaag
      961 aggataccta aaaatgcgat taaaaaggta agagcgttca gtaaggaaat aaactggatg
     1021 gatagaatgc ctagtaagac tcctcctagg atattactga ttgttttcac taaactaaca
     1081 gttgactgtt taaatccaat agcttctgcc agatggtctt gcccaataat tctaatgaaa
     1141 atcggagtga gcatggcgcc tgaaaaagca ctcaatgtat cagacacgag gttaagcaga
     1201 caaataaagg ttactagcaa caaggaaaaa gactgccctg aaagcgatag ggacactata
     1261 gagtaaagca aaaattttgt aaaactaatg actgtgtatt tcaagacacg atgatgttga
     1321 aaatctgcca aaactcccag aaagatttgt aaaatttggg gaagggtttc tgaaatcgta
     1381 atgagtaaaa tcgccaaagg tgcaaaagac gcatctgcca cataattcag aaaggccaga
     1441 taaaaaatcg tatccccaag cgttgaaatc cactggttga tagttaattg cctaaaatct
     1501 ctattttgaa gaaatacttt catcacaact ccttcttaag ttcaaatggg aatctttccc
     1561 cagaaataga ccgcgatact actaacaacc aaaattacag taacatcaaa agctgaccaa
     1621 tgccgttgta gactatatgc agtccaatag gccaataaat tgactttgtc attctaaata
     1681 agactgcaaa tataagacct ccacccatat agaagacaaa gtctgtcaag acccaaccgt
     1741 gattactaat gtgcgagacc ccaaataaaa cagcggaacc aagtacatct agcccccatt
     1801 tctttccttt ttccagagca gtcatcacta atccacgata aatcatgtct tcaaaaatgg
     1861 gacctgcaat cacaggataa aaaaaataca tcaaaaatgc cgtagctcct gtaaaagtag
     1921 gagcagcatg ttgataagaa atttcatttc gagtaggtgg gaaaagaaaa aaggtgacaa
     1981 aattccaagc aacaaaagca agcagagcta ggaaggaata gaaaagatag gatcctttaa
     2041 actttctact attgattttc tgccatttcc ccgaccaaat catagcaata agagcaaata
     2101 aaaccacaag aaaattcaac atcatatccg acagataata ggcaaagtca gatagcccag
     2161 caacaaggtc gctgcgtaaa actaaaacac tgaacttctg gtcagcaata actagtagaa
     2221 aaactataat aaagtagcgg tgtgagatta tctttttcat tctattttct cctatactat
     2281 gaaataaaga cagtccctac ccaagaaaaa ggcaaggact ctgaatatca ataatggcga
     2341 cgattaacag tggaagaatc atggttaaaa tatttcttcc agaaattagt gattgaccaa
     2401 gacgttccta aacctcccca agcaccggct gggataacag cattattccc aaattcccct
     2461 ccataaactg tctccaactc agcttctgtc aattccattg tttctgcaaa ttgtaaattt
     2521 aacatctttt acactccttc aattatcttc atttgtaaac cacttctgcg acctaggatt
     2581 tgcttcaagt gctttacaag tacagtataa cacgaaaatt ggcttatttt aaaaaatcgc
     2641 atatttgata ttttttctta tagaaatttc ttatttgcga ttttgataga tttgattatt
     2701 tccctggtat aataaagtta ttactaacaa ggaggaatat aatagatgaa gaaaagaaaa
     2761 atccaactga tactcctact tatttcggag tgggttattg ccattccatt tttaactaat
     2821 ctataagttc tttatattgc tgaaaacgca attcaaaaag ggatgttaat tgtggatttt
     2881 ctaatacctg cagagattgg ataaagcgtt caatctcttt ttgattgctt ccctttgttt
     2941 gaagaaagac actcatcttc tttaaaaatt gccacgatac tttttcaaaa acatcatacg
     3001 gtcgtaacat cctctccaac tcggcttcga agattgggat gtaggagaaa agttttcgct
     3061 ccatgagttc tgataagata tttaagagtc cttgcttcat atacaatcga ttgtgtacta
     3121 actctttaaa ttctttggat ttttcgagta aggaggttga taaaaaaaat cagatcttga
     3181 ttgctcaaga agggcatggt attgcaaaag agatagagtt caaaccaggt ccaagactcg
     3241 atagcataga gataggtggt caaaaactcg ctatcctcct ctgctagtgg gtagctttta
     3301 tttagtgaat ggatggcatc tttaatcacg atggcattca aacgacgata ggtctgcgcc
     3361 atctgttctt gatcgacttc ctccaatagc tgctctaaag cagctatatc ctgatgggca
     3421 aagcgattca caacctttcg accgattcgc atatgtggag attcttgata gttgatgagc
     3481 ttgtgcccaa actcatcaat ggtcacattt ataccttgga tagctagaat caacttatcc
     3541 gcagacagca tagactgccc tagttcaaac ttggacaact gagaagctgt tagaccctca
     3601 caagccacat ctgtctgctt aagctttctc gccaaacgta attccttgta aaattccccc
     3661 agttccattt tttcaatcat cctaccacct cctagctttt gcatattata tcattatttg
     3721 tgttcatttg tcaaaacatt ctgacacttt ggtgattgaa aaagccagcc ttaagctgac
     3781 tctaaaagga ccgagccttg tacaatacag aactcaatcc tcgttctaaa tagaatgtct
     3841 aacttttttg ggcagtacac gagcttgggg aacagccact ggaacgatga ggtgtgagct
     3901 caaaatatcc tccagttatg tttttcctaa tagtataccg gaagagtgaa aggattttat
     3961 aatggagcgg ttacaaagaa cctactttct a
//
LOCUS       DAVKMO010000082         3725 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVKMO010000082 DAVKMO010000000
VERSION     DAVKMO010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3725
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.082"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            71..298
                     /locus_tag="VW361_001958"
     CDS             71..298
                     /locus_tag="VW361_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744933.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            586..3468
                     /gene="nanA"
                     /locus_tag="VW361_001959"
     CDS             586..3468
                     /gene="nanA"
                     /locus_tag="VW361_001959"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU9744934.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPKGRVRLYVNGVLSRTSLRSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NERAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWDFLSKDLISPTEAKVKRTREMGKGVIG
                     LEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKGSIESM
                     HNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLVTLTTK
                     EDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1271 a          627 c          843 g          984 t
ORIGIN      
        1 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
       61 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      121 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      181 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      241 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      301 aggaagtatg gtgtaaatag cataggctga tgtccatcat ttgcttataa agagatattt
      361 tagtttaatt gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga
      421 aaggagaggg gaaatttggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      481 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      541 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt
      601 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      661 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
      721 cctctggcaa atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag
      781 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
      841 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
      901 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
      961 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1021 gatgccaagg ccccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat
     1081 gagtacttca ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat
     1141 gggaaacagt tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg
     1201 aattctgtga ctttcacagt tgaaaaaccg acagcagaac tacctaaagg ccgagtgcgc
     1261 ctctacgtaa acggggtatt atctcgaaca agtctgagat ctggcaattt cattaaagat
     1321 atgccagatg taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg
     1381 gggtcaaatc tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag
     1441 gtacaaaaac gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga
     1501 gcggctttaa cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa
     1561 gatggaatca agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc
     1621 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1681 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     1741 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     1801 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     1861 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     1921 tatcaaatcc tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     1981 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2041 gcctatagcg acaagggtga tctatacaag ggtaaccaat tactaggcaa tatctacttc
     2101 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2161 agtgatgacg acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc
     2221 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2281 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttaaatggc
     2341 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2401 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2461 gaacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2521 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2581 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2641 atccatacga tgcacgaagg aaaagaatac atcatcctca gtaatgcagg tggaccgaaa
     2701 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     2761 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     2821 ggggagtatg gtatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     2881 tttagaaaat ttaattggga ctttttgagc aaagatctga tttctcctac cgaagcgaaa
     2941 gtgaagcgaa ctagagagat gggcaaagga gttattggct tggagttcga ctcagaagta
     3001 ttggtcaaca aggctccaac ccttcaattg gcaaatggta aaacagcgac tttcctaact
     3061 cagtatgata gcaagacctt gttgtttgca gtagataagg aagatatcgg acaggaaatt
     3121 attggtatag ctaaaggaag catcgaaagt atgcataatc ttcctgtaaa tctagcaggt
     3181 gccagagttc ctggcggagt aaatggtagc aaagcagcgg tgcatgaagt tccagaattt
     3241 acagggggag ttaatggtac agagccagct gttcatgaaa tcgcagagta taagggatct
     3301 gattcgcttg taactcttac tacaaaagaa gattatactt acaaagctcc tcttgctcag
     3361 caggcacttc ctgaaacagg aaacaaggag agtgacctcc tagcttcact aggactaaca
     3421 gctttcttcc ttggtctgtt tacgctaggg aaaaagagag aacaataaga gaagaattct
     3481 aaacatttga ttttgtaaaa atagaaggag atagcaggtt ttcaagcctg ctatcttttt
     3541 ttgatgacat tcaggctgat acgaaatcat aagaggtctg aaactacttt cagagtagtc
     3601 tgttctataa aatatagtag attgaaataa gatgtgaaca actctatcag gaaagtcaaa
     3661 ttaatttata gaaaaatttt agcagtcaag gtgtactgtt atagattcaa tatattatgt
     3721 gacta
//
LOCUS       DAVKMO010000083         3440 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVKMO010000083 DAVKMO010000000
VERSION     DAVKMO010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3440
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.083"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            136..2769
                     /gene="polA"
                     /locus_tag="VW361_001960"
     CDS             136..2769
                     /gene="polA"
                     /locus_tag="VW361_001960"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU9744935.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGVKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHIELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            2854..3291
                     /locus_tag="VW361_001961"
     CDS             2854..3291
                     /locus_tag="VW361_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU9744936.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
BASE COUNT          931 a          605 c          883 g         1021 t
ORIGIN      
        1 tatgttatag cacattttta aatctaggtt tactaaattc tctggctcta tctatttatt
       61 cggaaaaagt ttgaaaaata cttgctctag ctcttcccaa tggtattttt tgattctttc
      121 ctttataatg ggtgtatgga taagaaaaaa ttattattga ttgatgggtc ttctgtagct
      181 tttcgggcgt tttttgcgct gtatcagcag ttggaccgtt ttaagaatgc ggctggtttg
      241 cataccaatg cgatttatgg tttccagttg atgttgagtc atttgttgga gcgggttgag
      301 ccgagtcata ttttggtggc ttttgatgcg ggaaagacga ccttccggac agagatgtat
      361 gcggactata agggtggtcg ggccaagact cctgatgagt ttcgtgagca atttcctttc
      421 attcgtgagt tgctggatca tatggggatt cgtcactatg agctggctca gtatgaggcg
      481 gatgacatca ttgggacgct ggataagcta gcagagcagg atggttttga tattaccatt
      541 gtcagtgggg acaaggattt gattcagctg acggatgagc atacggtggt tgaaatttcc
      601 aagaaaggtg tggctgagtt tgaggccttt acgccagatt acctcatgga agaaatgggc
      661 ctcacaccag ctcagtttat cgatctcaag gcgctcatgg gtgataagtc ggataatatc
      721 cctggggtga ccaaagtcgg tgaaaagacg ggtgttaagc tcttgctgga gcatggttcg
      781 cttgagggga tttatgaaaa tattgatgga atgaagactt ctaagatgaa ggaaaatctc
      841 atcaatgaca aggaacaggc ctttttgtct aaaacactag cgaccattga taccaaggca
      901 ccgattgcga ttggtttaga ggacttggtc tatagtggtc cagatgttga aaatcttggg
      961 aaattttacg atgagatggg cttcaaacag ctcaagcagg ctttaaatgt gtcgtcagct
     1021 gatgtggctg agggtttgga ttttactatt gttgaccaaa tcagtcaaga tatgctgagt
     1081 gaagagtcta tcttccacat tgagcttttt ggtgagaatt accatacgga taatttggtt
     1141 ggatttgcct ggtcttgtgg ggataagctc tatgccacag acaagcttga gctgttgcaa
     1201 gacccgattt tcaaggattt cttagaaaaa acatctctga gagtttatga ctttaagaag
     1261 gttaaagttc ttttgcaacg ttttggtgtg gatttgcagg cgcctgcttt tgacatccgt
     1321 ttggctaaat acctcctttc gactgtggag gacaatgaaa ttgcgaccat cgctagtctt
     1381 tatggtcaga cttacttggt tgatgatgaa actttctacg gtaagggtgt taaaaaggcc
     1441 attcctgaac gtgagaaatt cttggaacac ttagcttgta aacttgctgt tttggtagaa
     1501 acagagccta ttttacttga aaaactcagc gaaaatgggc aattagagct tctttatgat
     1561 atggagcaac ctctggcttt tgtccttgcc aagatggaaa ttgctgggat tatggtcaag
     1621 aaagagacct tgcttgagat gcaggctgaa aatgagcttg tcattgaaaa actgactcaa
     1681 gagatttacg agctggctgg tgaggagttt aatgtcaact cgcctaagca gttgggcgtg
     1741 cttctctttg agaaattggg acttcctcta gaatacacta agaaaaccaa gacaggttat
     1801 tcgacagcag tggatgtttt ggagcgtctc gctcctattg ctccgattgt taagaaaatc
     1861 ctggattacc gtcaaattgc taagattcaa tctacttatg taattggctt gcaggactgg
     1921 attttggctg atggaaagat tcatactcgc tatgtgcagg atttgaccca aaccgggcgt
     1981 ttgtctagtg tggatccaaa cttgcaaaat attcctgccc gattggaaca ggggcgcttg
     2041 attcggaagg cttttgtgcc agagtgggag gatagtgtgc tactcagctc tgactattca
     2101 cagattgaat tgcgcgtttt ggcgcatatt tctaaggatg agcacttgat taaggccttc
     2161 caagaggggg cagatatcca tacttcgaca gccatgcggg tctttggcat tgagcgtcct
     2221 gatgatgtga ctgcaaacga ccgtcgcaat gccaaggcag ttaactttgg agtggtttat
     2281 gggatttcag actttggctt gtctaataat ttgggaatta gtcgtaagga agctaaagcc
     2341 tacattgata cctactttga acgttttcca ggtattaaaa actacatgga tgaagtggtg
     2401 cgggaggcgc gtgataaggg ctatgtagag accctcttta agcgtcgccg tgagttgcca
     2461 gatatcaatt cgcgcaactt caatattcgt ggttttgcgg agcgaactgc tatcaactca
     2521 cctatccagg gttcggcagc agatattctc aagattgcca tgattcagct ggataaagcc
     2581 ttggttgcag gtggttatca gactaagatg ctgttacaag tgcacgatga aatcgtcctt
     2641 gaagtgccta aatctgaatt ggtagagatg aaaaaattgg tgaaacaaac catggaagaa
     2701 gccattcaac tcagtgttcc tcttatcgca gatgagaatg aaggggcaac ctggtacgag
     2761 gctaaataaa aagggggcta gtcctccttt tttgtagtag aattctgcaa accttttcaa
     2821 aatgtgctat actgatgaaa aaggaggatt tctatgagtc aagaatttat caatccaagt
     2881 gatggcgtga ttcgtcagta tctcgcaacg agtaaaaccc ttgctgtggt gggtttgtct
     2941 gaccgtgaag aaacaaccag caatcgagta acaaaggaaa tgcaggctcg gggctataaa
     3001 atcatcccag tcaatcccaa ggcggcaggt ggcgaaatct tgggtgaaaa ggcttatgct
     3061 agcctcgctg aaattccttt tcctgtagat attgtcaatg tttatcgtcg cagtgaattt
     3121 ctgcccgatg tggcgcgtga ttttctcaaa gctgatgcca agattttttg ggcacagcta
     3181 ggacttgaaa gtttagaagc gaaagagatt ttgcgtgatg gtggatgtga tgatatcgtg
     3241 atgaatcgct gtatcaagag agaacatact cgcttgattg aggaagcata agaaaaaggt
     3301 agctgatggg ctaccttttg tgttatactc aatgaaaatc aaagagcaaa ctaggaaact
     3361 agctgcgggt tgctcaaaac actgttttga ggttgtagat agaactgacg aagtcagctc
     3421 aaaacaccgt tttgaggttg
//
LOCUS       DAVKMO010000084         3363 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVKMO010000084 DAVKMO010000000
VERSION     DAVKMO010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3363
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.084"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..708)
                     /locus_tag="VW361_001962"
     CDS             complement(<1..708)
                     /locus_tag="VW361_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9744937.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQ
                     NKPEKSFRYIDTSSIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLK
                     NIAVVRELKEYLIASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDY
                     NFNLLLIALPPLSEQQRI"
     gene            complement(708..2171)
                     /locus_tag="VW361_001963"
     CDS             complement(708..2171)
                     /locus_tag="VW361_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9744938.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILDPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            complement(2184..>3363)
                     /locus_tag="VW361_001964"
     CDS             complement(2184..>3363)
                     /locus_tag="VW361_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HEU9744939.1"
                     /translation="NGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFD
                     KTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNF
                     PAIVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDF
                     RNVTNLFADPDFDGDPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNST
                     VQVLDENGKLITESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYLD
                     AIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEIL
                     LNKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA
                     "
BASE COUNT         1005 a          662 c          502 g         1194 t
ORIGIN      
        1 tattcgttgt tgttcggata gtggggggag agcaattaat aatagattaa aattataatc
       61 attgattgca ggataacttg ttccagtaga tttattatta acacgattga taaaattatc
      121 tgataataaa taatatttca aatatgtttc gttaagtaaa gtatccaaaa caataaatgc
      181 tgtactagct atcaaatact ctttaagttc tctaactaca gcaatatttt ttagatatgg
      241 tctaactgtt gaaaataaga cactattctg cgaaactaat tttctagcac gggaaggcgc
      301 ttgttcaggt gaaagatatt gtagattttt gtagttgatt atgttctttt ttctatcaat
      361 actagacgta tctatatacc taaaggattt ctctggctta ttttgcccaa aattccaata
      421 aattgatttt atcctcaccc actcccaagt atcaggaata tcataaggaa catcaatttc
      481 ttgagtgctt ccatcagcaa acttcccata atgtttccca tcatcaccac gaaatatctc
      541 agtttccttt ttatctcgtt tgatttttcc ttcactgata agtttttctt tttcagcttt
      601 aattctcttt aataattcac ttgcaggttc gtcattggga ttttgcggca ctaatttccc
      661 ttccatcgct ctttggagaa tacttgcttt aagttgttct ggtgtcatta tttgtcctcc
      721 aacaactgca aaatatcagc taatacatta tcaatcttat gatttaaagt tgctctttcc
      781 gcttgataat tctgaatcaa ctcaaaggga tctaagattt cctcttcctc ttttggaaag
      841 ccacactggt ctaaattata attcaactca gccaattcac taggtgtaaa tgatttagat
      901 ttgtagaact taccttccag aatctcttca cgattttccc accagtcacg aacaggattg
      961 aagtgttctg acttcatcgg cttagttttc gagaaatttt tataaccatc tggcatatct
     1021 aaacgataaa accaagtttc ttctgttttc tttgttttat caaagaaaag aatgttcgta
     1081 tggattcctg tatacggtgc aaagacacta tgaggcaacc taataatcgt atgcaagttg
     1141 aactcatcta ccagtttttg tttcaagcga gtttttacac cttcaccaaa tagaaaacca
     1201 tcaggtaaaa taactccaac acgaccattt tctttcaaac gatacataat gacagccata
     1261 aataaatcag ctgtttcaga actccgtaat tctgctggaa agttattttt tattgtttct
     1321 aattctgacc ctccaaaagg tggattcatc ataataatgt caaatttttc atcatccgta
     1381 tattcacgaa catttttctc caaagtattt ccatgaacaa ttttagggtc atcaatttcg
     1441 tgaagaaaca gatttgtaac tgctaaaaga tgaggaaatg ctttcttttc aataccaaaa
     1501 acagctgtat tatatttttt ggtatcttca ctagttttac gttgactact taaacggttc
     1561 agagtcgaag tcaagaagcc tcctgttccg caagcaaggt ctgccattga ttctccaagt
     1621 tttgggttaa gaacttcggc aataaaatca gtcgctgcac gtggcgtata aaattctcct
     1681 gagttcccag cattttgaat atctttaaga attttttcgt aaatatcatt aaacgaatga
     1741 cgatcttcag ggctattgaa atcaacttca tcaataacat tgatgacttg gcgtaacaag
     1801 acgccatttt tcatatagtt gttcgcatct tcaaaagctg atttaacaat cgtttttcga
     1861 ataggcatat ttgaagttat ttcaagctct ttcaactctt tgaataactt gttattgaca
     1921 aaatcaagta attcatcgcc tgtcaatacc cgttccccat tttgagcatg agcccaattt
     1981 cgccatttta attcctctgg gataattgac tcatactcgt cttcttctaa ttcccaaacc
     2041 atttcacggc tatcataaat ttttaagaat aataaccaag acatttgctc aatacgttga
     2101 gcatcaccat taacaccagc atcgtttcga gtgatatctt gaattctttt tacaaatgat
     2161 gtaattgaca tactttcctt tcattaagct actgtaaata gctcttgctc caattcttta
     2221 attgcttgta aatatcgttt tttatctcca aaataagtat tgatgatttt gaaggttcca
     2281 ccatatatct gaaattctgg aagttttaat gtttcaatgc tttcgagttc tccaatacct
     2341 ttatccatgt atttgttcag taaaatttcc aaaacagcac gcgcttcctc actatattta
     2401 tataaatatc cgctttgttt gagtttattg atacgttccg ttttggttaa ttctttttga
     2461 ccataggcaa gttttaggag taaatcaaaa tcatcgattt cttgttctga tattccctcc
     2521 gactctcgaa tagcatctag ataaactcct tttttataaa gttcgtctaa gataagcttc
     2581 tttttatccg ccgtatgcca aactgtgata aaatcgttca aagtggcgta gctacctaag
     2641 atattcttcc gagtgtagtc ggtcaggctt tcggtaatca gtttcccgtt ttcatctaat
     2701 acttgaacag tagaattaag aatggtaacc tgcttgtctg taacgatata tttttctact
     2761 gggtcacctt cctcatctac gaaaccgggc gtagaaccac tgactgtttt cgcacctgtt
     2821 tccagcacct tcacaggatc accatcaaaa tcagggtcag caaacaaatt ggtaacattt
     2881 cgaaaatcaa taatcgtaaa aaattctttc cccttttgag gataaagacg tgtgccacga
     2941 ccaataattt gtttaaattc agtcatggat tggatattag agtctaaaac aatcaaacga
     3001 catgttttag cattaactcc tgtcgttaat aatttagacg ttgttacaat agcgggaaaa
     3061 ttagaattga catccataaa gttatccagt tgagcttttc cttcagcgtt gtcaccagtt
     3121 acttgcatga cataacgata gtcttcttgg actaagtcta gattctcttt tacaagtgca
     3181 gcacgcattc gctcggcatg gtcaatatca acacaaaaaa caattgtttt atcaaatcgt
     3241 gcattgcttt gcttcatata atcagaaaca aacttggcaa ctctttgcgt tctatcatca
     3301 atgacaatgg ttttatcaaa atctttcctg ccgtagtacc tatcttctat taattgtccg
     3361 tta
//
LOCUS       DAVKMO010000085         3141 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVKMO010000085 DAVKMO010000000
VERSION     DAVKMO010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3141
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.085"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(140..673)
                     /locus_tag="VW361_001965"
     CDS             complement(140..673)
                     /locus_tag="VW361_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU9744940.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTAGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(762..1538)
                     /gene="recX"
                     /locus_tag="VW361_001966"
     CDS             complement(762..1538)
                     /gene="recX"
                     /locus_tag="VW361_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU9744941.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKLISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKKISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            1576..2931
                     /gene="rlmD"
                     /locus_tag="VW361_001967"
     CDS             1576..2931
                     /gene="rlmD"
                     /locus_tag="VW361_001967"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9744942.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVIVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            2993..3064
                     /locus_tag="VW361_001968"
     tRNA            2993..3064
                     /locus_tag="VW361_001968"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3026..3028,aa:Glu,seq:ttc)
BASE COUNT         1000 a          559 c          587 g          995 t
ORIGIN      
        1 tacgaattct gcataaattt ctttctagta atgtgttgta actctgctat aatggattta
       61 ttcctttttg tgtttacaca atttatttta tactaccaaa aaaacaaggt caggattttg
      121 ttcctgacct ttgacaactt taccgattct ttagttctac atagcgcttg taccaaatgt
      181 ttacataggc ttctgagaaa ggaccacgtc cattgttaat ccaatcaaca agaattttga
      241 catgttcttt taaaatatag tccaagtcat cagaataatt cattttgcgt ttgtgacgct
      301 cgtactcttc aacgtccaag agacgttttt ccccagctgt aaaaatttta acatccaaat
      361 cgtaatcaat atacttcagt gcttcttcat ccagatagta ggggctagcc atattgcaat
      421 agtaagaagt tccattatca cgaatcatgg caatgatatt aaaccaatat ttcttgtgaa
      481 agtaaacaat agccggttct cgagtgaccc aacgacgacc atcactttcg gtaacaagtg
      541 tatgatcgtt gacaccaata atggcgtttt ctgttgtttt tagtaccatg gtgtcccgcc
      601 aagttcggtg gagactccca tcatgcttat aactttgaat tgtaataaag tcgccttctt
      661 ttggaagctt cataactaac caactttcta caatttataa gtttatcatt tactattgta
      721 ccataaaatt acctaaaatc tgtgaatttc acttggaaat attaaagata ttctctaaga
      781 gcgcttgcta tatccgaaaa atcgtagccc tttcgtgcta aaacttgagt taaacgctgc
      841 ttcagttcgt atccttcata ctttcgagca tacttagtat attgcttatc aagttccttg
      901 aagatgagtt cttgagtcgt ttcttggtca acttggctat ctaagtcgtc aaaggcaatt
      961 ttagcatcag aataagagaa gcccttgtta gtcaagttct ggataatctt atcttgcagg
     1021 gcacgagctg gaagttttcc ctcatatttt ttcaatagtt tattagctac acgttgagca
     1081 acttcagaaa aatcaaattc tttcaagttc tcttctatag tagattttga aatctttttt
     1141 tgagctagtt tctgagtcag cacataagga cccttgtctc ctgaaagttg attggtattg
     1201 atgatagcat aagcgtactg accatcatta atccacttat cttctttaag attagcaata
     1261 acttgagaaa cgatgttttt atcaatatcg tattttttca gatattctct gacttctttt
     1321 tcagtgcgtg ctttaaagga taagtggtag agggccagat tcttaccata agaaaattga
     1381 gcaaagtctt gaatctcttt caattcctct tcgcttatca gcttatctct cgataacata
     1441 aaacgaacaa ttgtatcttc ggtgatatag catttgtcgc cattatcaag ctccatcaga
     1501 tagagtcttt ttttcttttc aagttttgtg attttcatag ctctattata actcaaaatg
     1561 tgataagata ggggtatgaa tctgaaagtg aaacaaaaaa taccattaaa aatcaagcgc
     1621 atgggaatta acggtgaggg aatcggcttt taccaaaaaa cattagtctt tgtaccagga
     1681 gctctcaaag gcgaagatat ctattgtcag attacttcta ttagacgcaa ctttgttgaa
     1741 gcaaaattac tgaaggtcaa caagaagtct aaatttcgaa ttgtgccatc ttgtactatt
     1801 tataatgaat gcggaggctg ccaaatcatg cacctgcatt atgataagca gctggagttc
     1861 aagacggact tacttcatca agcgctgaaa aaatttgctc ctgcaggata tgaaaattat
     1921 gaaattcgtc caactattgg aatgcaggaa ccaaaatatt acagagctaa gttacaattt
     1981 cagactcgaa aatttaaaaa tcaggtcaag gcgggcttat atgcacaaaa ctctcactat
     2041 ttagtagagt tgaaagactg cctggtacaa gataaggaaa cccaagtgat tgctaatcgc
     2101 ttagcagaat tacttactta tcaccagatt ccaatcacgg atgagagaaa agttctaggt
     2161 gtccgtacta ttatggtccg acgcgcgaga aagaccggac aggttcagat tattattgtt
     2221 acaaaccgcc agcttaattt aactcaattg gtaaaagagt tggttaaaga tttcccagaa
     2281 gttgtgatag tagctgttaa tacaaataca gctaaaacca gtgagatata tggtgaaaag
     2341 acagagatta tctgggggca agagagtatt caagaaggtg tactcaatta tgaattttca
     2401 ctatcccctc gagcttttta tcaactaaat cctgagcaaa cagaagtcct ctatagcgaa
     2461 gcagtaaaag cgctggatgt tgataaagaa gaccatttga ttgacgctta ttgtggagtt
     2521 ggaacgattg gatttgcctt tgcaaagaaa gtaaaaacac tcagaggtat ggatattatt
     2581 ccagaagcta ttgaagatgc caagcgaaat gctaaaagaa tgggatttga caatactcat
     2641 tatgaagctg gaacggcaga agagattatt cctcgttggt acaaggaagg ctaccgagca
     2701 gatgctttga ttgttgaccc accacgtaca ggtctggatg ataagttatt agatactatt
     2761 cttacttatg taccagaaaa aatggtttat atttcttgta atgtttcgac cttggctcgt
     2821 gatttggtac gcttagtaga agtctatgat cttcattata tccagtcggt cgatatgttc
     2881 ccacatacag ctcgaactga agctgttgta aaattaataa aaaaagttta aaaaaggtgt
     2941 tgacaaagtt tgaaaagact gtataatagt aagagttgaa aataacaact caggtccgtt
     3001 ggtcaagggg ttaagacacc gccttttcac ggcggtaaca cgggttcgaa tcccgtacgg
     3061 actatggtat gttgcggttg gaacacttga tgaaaaaaag tttaaaaaag cttaaaaatc
     3121 ttcaaaaaaa gtgttgacaa g
//
LOCUS       DAVKMO010000086         2991 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVKMO010000086 DAVKMO010000000
VERSION     DAVKMO010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2991
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.086"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..335)
                     /locus_tag="VW361_001969"
     CDS             complement(<1..335)
                     /locus_tag="VW361_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744943.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGD"
     gene            complement(349..1062)
                     /locus_tag="VW361_001970"
     CDS             complement(349..1062)
                     /locus_tag="VW361_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU9744944.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1521..1901)
                     /locus_tag="VW361_001971"
     CDS             complement(1521..1901)
                     /locus_tag="VW361_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU9744945.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(2323..>2991)
                     /gene="phtB"
                     /locus_tag="VW361_001972"
     CDS             complement(2323..>2991)
                     /gene="phtB"
                     /locus_tag="VW361_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HEU9744946.1"
                     /translation="GNTEAKGAEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIP
                     HYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQ
                     RNKNGQADTNQTEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEESPEESEEPQVET
                     EKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALL
                     KESK"
BASE COUNT          903 a          595 c          485 g         1008 t
ORIGIN      
        1 aaatctccca tacagccatt acgattcata ttgaggctat attttcgatt agtaagataa
       61 ttcggaaata tatttcctat tactctaaga ttatctactt gtgaatccct tctcccaata
      121 taatcccctt ctttgactaa tgatggagat ttccaagtaa aaattaaatc gccagagaaa
      181 tttttcttat caaaaaactt aaaaagagat tgataaatac tatttgctaa ttgacaagtg
      241 tcagatgtaa attcataatt aacagcttca ttaaaatcaa cttcagacat ttcaatgtac
      301 tcttcaatag taatattagc tttttttgta gtcattagct aatctccttt aaaacgtgat
      361 cttttcaaga atatttttat ctaaacaatc cagcaagtct tggtaagaat agacttcgta
      421 agtcggctgg gcttgtgtgt gattttcgag gtgatgagga ttataccaga tagtgtcaat
      481 ccccgcatta ttgccacctt gaatgtcggc ggttagagaa tctccaatca tcagcgtctt
      541 ttctttacta aatccagcaa tttgctggcc aatcttttca taaaaaagag catccggctt
      601 ttgagtttgc aactgttctg agataaagac ttgattgaaa taaggtgcta gaccagattg
      661 agccaaacgt cctgtctgaa tggcagtaat gccatttgtc gcagcataca agttataatc
      721 acgctcaatg aggctgtcca agagatcatg agcgcccgat agtgtttgtc cctgctgggc
      781 gaggtaaaat tggtaacgct gggcaagaaa actaccgtct ttttcctgtc caaaatgagc
      841 aaataaacga gaaaagcgcg tgttaaccag ctcttgttta ctgattttct tcagctccaa
      901 gtctttccag agagccttgt tcataggaac gtaataatct ttataagcct gaatatccgc
      961 aactccttct tcttttagaa gttgagtcaa agccacatcc tcagcagcat caaaatcaag
     1021 aagagtgtgg tcgaggtcga agagtagaaa tttgtagaac aatttgaggt tttcctttct
     1081 gaaaattcat taagaacatt atatcataaa gcacctcata caattaacta atttaatcac
     1141 ttaaaaaaaa ttcgaacact ttctatacaa ctgacagctc aaatctttca gaatagaaca
     1201 atactaacta tcgaacaccc cgtcttcata aatacatatg taattctagg cctagaattc
     1261 ctataaacta aatgctttca tactcttcca agtaattgat tgccttaaat tttaattttt
     1321 gaaggtttct aaagctagaa tagccccatc acaatcagtt ttgattgatt cacaatttag
     1381 aaacactata gtttcactcc tgttaaaata aaaaggaact gcataaagca atccctttct
     1441 gattttgaaa tcatttactt aacattttat agttgagata atcaatagct tatctataaa
     1501 aagagttata gtaaaattcc ttatttattg atttcaagct ccgctaactg tatttgaata
     1561 actgacagtt ctgcaccagc ctgaagaaga gcagctgcat tataggcacc ttctacaatt
     1621 ggaaccctgt tgatgatgat acttttatca ctgaaatcag tcaccatttt taagttcatt
     1681 ttagcagaac ctaggtcaaa aaaggcaagt aaagtatctg ctggattttc ggaaacaacc
     1741 ctatctactt gatcaaaact cgttccaatt cctccgccct cggttcctcc tacataagta
     1801 atcggaacat ctttagctac tttactaatc agttcaacaa caccttctgc aatgtgtttg
     1861 gaatgtgaaa cgataacaag accaatacca atactttcca tcaaaccact ccagtttcta
     1921 aaatagcagt aaagagtaat cctgatgaga atgatccagg atcaatatgt ccaagaaacc
     1981 acatgctcct aagacaagag ctaacagact ggccatcaat aatagtattg ttcttttttt
     2041 catcattact ccttaactag tgtttaactg attaattagc cagtaaatag tttatcttta
     2101 tttacactat ctgttaagat atagtaaaat gaaataagaa caggacagtc aaatcgattt
     2161 ctaacaatgt tttagaagta gaggtatact attctagttt caatctacta tattttgcac
     2221 attttcatga aaaaaatgag aactagaact cacattctgc tctcattttt cgttttcccg
     2281 ttctcctatc ctgtttttag gagttagaaa atgctgctac ctttacttac tctcctttaa
     2341 taaagccaat agtttttcag cttctgccat aatagtattg ttgtcctggg tgccaaatag
     2401 taaattattt tttaatcctg tgagagtctc tttggcattg gacttgataa ttggatcctg
     2461 gatttttcca agtaaatctt cagcctctct cagtttttct tcaacctttt cagtctcgac
     2521 ctgaggttct tctgattcct ctggtgattc ttctggttcc tctgttggtt ttggagactc
     2581 tggtttctcg ctttgcggtt tctcttctcg aggggtttct tcctcaggtt tttctgtctg
     2641 aggtttctcc gtttgattgg tatcagcttg accatttttg tttctttgaa catggtcgct
     2701 agcgttacca aaaccattat ctgaatgcgg acgttcgttt ggatgttcga catagtactt
     2761 gacagtcgcc aaaagatcct caagagtata ccccttaggt gcctcataaa ggccttcgtc
     2821 aaaccactca aatttgatgt tatggtaatg gtcataatga ggtatgatta aactaccgtt
     2881 tttgacttct acagtatatt gaagattgta aggcatacga tcaagtggca ccttcttagc
     2941 tgctttcacg cggttgtaga tagcttctgc tccttttgcc tcagtatttc c
//
LOCUS       DAVKMO010000087         2814 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVKMO010000087 DAVKMO010000000
VERSION     DAVKMO010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2814
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.087"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            295..1257
                     /locus_tag="VW361_001973"
     CDS             295..1257
                     /locus_tag="VW361_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU9744947.1"
                     /translation="MTSSTEFGNFVSNLSFQHGIAGLLFPLNKLYPPELDSKILSIIK
                     KAVTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANVTAKKLIENYDTL
                     EEIDFALGKSGVLLSLIKYYQFTNDNTLKIFIHNSIGEIYHYFLQRDTAKESILDYSF
                     AHGYCGIAYALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKG
                     ISGIILYLCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLM
                     KKIQQVILACSERDDHGLLMFQGDSGKADLFDFGIGSMGYIGVY"
     gene            1300..2532
                     /locus_tag="VW361_001974"
     CDS             1300..2532
                     /locus_tag="VW361_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9744948.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLTLITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(2650..>2814)
                     /locus_tag="VW361_001975"
     CDS             complement(2650..>2814)
                     /locus_tag="VW361_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9744949.1"
                     /translation="DGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGY
                     SVNYNGEWVR"
BASE COUNT          867 a          575 c          459 g          913 t
ORIGIN      
        1 ttatctcatt ttactataat atttgataag ttatcctaaa agtattatta tgttgttgtg
       61 ttatagattg attgaatcta actaaaggat cctattcaat tactagaact atcacatact
      121 caaggtcagc tcacagatga gcaactattt tggttacaat gtctactaaa tttaagtcaa
      181 acaaataatt tagtcaaaat taaaaaaata gaggaacata aatatgatta caaaacagaa
      241 tgtaatagtg ttctacaatt tttactagat aaaactgtaa attctgaagg aaggatcact
      301 tcttcaacag aatttggaaa tttcgtaagt aatttatcat tccaacacgg aatagctgga
      361 ctactgtttc ctctaaataa attgtacccc ccagaactgg attctaaaat actctctatc
      421 atcaagaagg cagtgacaat tagaacgaca catacatatg aatatcaata ctcactgcta
      481 tttggtgatg caggctatct atggttactc ctacatttat tttctatcag taaaaatcaa
      541 tactatctac aattagcaaa cgtcaccgct aaaaaattaa tagagaatta tgatactcta
      601 gaggaaatag actttgcatt gggaaaatct ggtgtcctat tatcattaat aaaatactat
      661 caatttacca atgacaatac tcttaaaatt ttcatccaca atagtatagg ggaaatttat
      721 cattatttcc tacaaagaga tacagccaaa gaaagcattt tagactatag ctttgctcat
      781 ggatattgtg gaattgcata tgctttattt gcctattcta aagtcttaga accttctatg
      841 ttctataatg atctccatac attccatact gaattaaaaa aattattaga aaaagttact
      901 tctaatactg aaaatttagg aaatttacaa ctttcttggt gcaaaggaat ttccggaata
      961 atcttatatc tttgtatgta cgattgtgac ggaaacaaag atattattag taaatatcaa
     1021 gaatttgttt ttaaccatca tctaaaaatg atgacaggat attgccacgg aataactagc
     1081 ttactacaaa ccactgtcta caatcaaaac aaattactga tgaaaaaaat ccaacaggta
     1141 attttagcat gttctgaacg agatgatcac ggtttactga tgtttcaagg agatagtggt
     1201 aaagcagatt tgtttgactt cggaatagga agcatggggt atattggtgt ctattaaata
     1261 ataaattccc attcgatgtg cagacataag gagaaaagta tgaaattatt ttggacaaac
     1321 aacatatata gacagttgct gctaaacagc tgtttttcat cattcggcga cagtattttc
     1381 tacctcgcca ttatcaatta tgtggctcag tacaatttcg ctccgctagc gattttactg
     1441 atttccattt cagagatggt tcccctacta tcgcaactct ttctcgggat tctaggagat
     1501 tttcaagaaa atagagtcaa acacgcactc tggattgcca aaatcaaaat cctgctctac
     1561 gctattttga cagtatttct cgtcttgtcg cccttttcat tagtttcagt cattatgatt
     1621 gtcatcatca acctcatctc tgacaccttg agctacctgt ctgcctacat gatgaacgcc
     1681 ctctacatca gtgtaattaa ggacgacctg catgatgcca tggggttcag gcagtctctg
     1741 atgagggttg tccgtattgt cgccaatctg gctggcgcat tccttatcaa tgttataagt
     1801 attcaaacta tttcccttat caacactctg acttttgtca ttgccttttt gggcctgtat
     1861 gttattcgac ataccttgta tgaggttgaa aaaagaattg aaatgtcaca tacagcactg
     1921 agttttaaga aatattttca acatcttaaa cagtcgctgg ctgtgctcct gaggttaaaa
     1981 gataccgtca tactactgtt tctgacgacc agtatgattg ccatcttgga tgtgtcccct
     2041 cggctgattg ccctccgctt catccaacag acactagcac aactgagcat tgggcaactc
     2101 ctcgccctgc tctccatcat catgtcttgt ggagctatcc ttggcaatat gaccagcagt
     2161 aatctattta aaaatatccg tttcacgcac ctcttggttt tctgtgagat ttccctattg
     2221 actctaataa ctagtatcct ttgtcaagcc tatatcgtaa ttttcatgac cagtttcatc
     2281 agttctacga ttatcggcat tctcagccct cgcctacaag cagctgtctt tgcccatatc
     2341 cccagtgaca agatggggac ggtgggctct gctctgagca cagtggacat tctcgccccg
     2401 tccctgctct ccctattagc cctatccata gcatcgggcg tttcggtgca gttagcattg
     2461 atatttttgt atcttatttt aattgctctt atcttttgtc aatggttagt caagttcaac
     2521 actcataact aacgaaaaag catgtgtaga tttcacatgc ttttaatctc cccaatcgtc
     2581 aggtcaagta caacaaagtc acttctttga ttaagcgagt gttctaatat aattataagc
     2641 gccctgtcat taccgaaccc attcgccatt atagttgaca gaatagccat ctacggtcgt
     2701 attcactgcc aaagcacctg agctataagc atagtaccag ttgccattga cctggaacca
     2761 acctgtcttc atatctccat tacctgcatt taggtagtac caagttgaac catc
//
LOCUS       DAVKMO010000088         2287 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVKMO010000088 DAVKMO010000000
VERSION     DAVKMO010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2287
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.088"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..222
                     /locus_tag="VW361_001976"
     CDS             <1..222
                     /locus_tag="VW361_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEU9744950.1"
                     /translation="VLDGYVISCEVKMMKPQKEIYLSLVNKYQLDIKDCIFLDDLEEN
                     VEAARTLGIKAFQIKERKEISNILKDLLN"
     gene            232..2259
                     /locus_tag="VW361_001977"
     CDS             232..2259
                     /locus_tag="VW361_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9744951.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIPIFEVDTYQSNKTLSSFDSDKIFEIVLEL
                     VRTEKLSNLYFISLTNEKEHSLFEYLTQKIKNSTHIQVQERLQLLSLYPTLKNFAKYD
                     CIFVDDEDLMHTLLDLFDWFTIIDRPKICLIGSRVWFEKRNLFYIHLDYRILALNTAE
                     NLESRNSSIVPVKDGKQILIDQLFDGECDDIYLLTVHSPMNKALEILSEKYKQISGKN
                     IKIIEKRYDELLEMIESGDVSSSFDMIRMDMAWLPTFGKKYFQEITSFRQTKSINQNI
                     SKSVSREYMYIDQKQYTFPLDVSSQILVYRKDLFEDSFLQRRYFEKTKRKLTVPKSYQ
                     EFDELSEFFTLTENPFSPTLYGHSLALSSSVRAACEFIPRFRERLAQSRMNLAVLPQV
                     LTEYEKSYQFTEKSFNSSWNDFVTNLNSGKTSMEIIFSNYTSPLFDGLNVSAQFEFAT
                     ATIPGNTPVIGGGSIGISKYSNRVEECLNFINWLYSEEISILLTSLGGFLPSKYVMQN
                     RMLQFQYPWLSSLEDTFSIGSRTKWYGFNTDFRFEQMLGQELIESVKHRYG"
BASE COUNT          823 a          273 c          386 g          805 t
ORIGIN      
        1 gttttagatg gttacgtaat ttcttgtgaa gttaaaatga tgaaaccaca aaaagaaatt
       61 tacttgtcat tagttaataa atatcaatta gatataaaag attgtatatt tttagatgat
      121 ttagaagaaa atgtagaagc tgcaagaact ctaggtatta aagcatttca aattaaagag
      181 cgtaaagaga tctcaaatat actaaaagat ctcttaaact agaggttaat tatggttaca
      241 ataaaagata ttgcaagagt gtctggagtc tcacatggga cagtttcaaa cgttttaaat
      301 aaaaaaggta atgtctcagc agctaaaata aagttagtag aagagactgc gaaaaaattg
      361 ggttataata tgaattctca agctcagttt cttcgaaaag gcgcttctag taaatgtttt
      421 ttcttgttat ttaataatgc acgcaaaaag tatgctgagt attttgcaga aattgatcag
      481 ttatctttag atgtagaata tgtttactta cataaattct cagagattaa aaataagata
      541 tctgcaattt taagtgaaaa tcctcaattt atagtttgct taggtttttc tccaaaaaga
      601 ttcgttgata ttgaagataa tattccgatt tttgaagtag atacatatca atctaataaa
      661 actttatctt cctttgatag tgataaaata tttgagattg tacttgagtt ggttcggact
      721 gaaaagctat ctaatttata ttttatttca cttactaatg aaaaagaaca ttctttattt
      781 gaatatttaa ctcaaaaaat aaaaaactca actcatatac aagtgcaaga acgtttacaa
      841 ttgttgtctc tatatcctac tctaaaaaac tttgcaaagt atgattgtat atttgttgat
      901 gatgaagatt tgatgcacac gctattagac ttatttgatt ggtttactat aattgataga
      961 ccaaaaatat gtttgatagg ttcacgtgtt tggttcgaaa aaagaaatct tttttatata
     1021 catttagatt atagaatatt ggcactcaat actgccgaaa atttagaaag tagaaatagt
     1081 tcaattgtac cagttaaaga tggcaaacaa attttaattg atcaattatt tgatggagaa
     1141 tgtgatgata tttatttact tactgtccat tcaccaatga ataaagcctt agaaatttta
     1201 tcagaaaagt ataaacaaat ttctgggaaa aatattaaaa ttatcgagaa aagatatgat
     1261 gaacttttgg agatgattga gtctggcgat gtttcatcca gttttgatat gattagaatg
     1321 gatatggctt ggcttccaac atttgggaaa aagtattttc aagagattac aagctttaga
     1381 caaacaaaaa gtattaatca aaatatttct aagtcggtgt ctcgagagta tatgtatatt
     1441 gatcagaagc aatatacttt tccattggat gttagtagtc agattttagt atatagaaaa
     1501 gacttatttg aagattcatt tttacaaaga cgatactttg aaaaaacaaa aagaaaatta
     1561 actgtaccaa aaagttatca agagtttgat gagttaagtg aattttttac attaacagaa
     1621 aatccatttt cacctacact ttatggccat agtttagctt taagttcttc agtgagagca
     1681 gcatgtgaat ttattcctcg gtttcgtgag agattagcac aatctagaat gaatcttgct
     1741 gtacttcctc aggttttaac tgagtatgag aaaagttatc agtttaccga aaaatcattt
     1801 aattcttcgt ggaacgattt cgttacgaac ttaaacagtg gtaaaacttc aatggaaata
     1861 attttttcaa attatactag tccattattt gatggtctca atgtttctgc tcagtttgag
     1921 tttgcaactg ccactatacc tggtaatact cctgtgatag gtggtggctc aattggaatt
     1981 tctaaatatt caaatagagt ggaagaatgt ctaaacttta ttaattggtt atattctgaa
     2041 gagatttcta ttttactaac atctctgggt ggttttttac catcaaagta tgtcatgcaa
     2101 aataggatgt tacaatttca atatccatgg ttatctagtt tagaagatac atttagtatt
     2161 gggagtagaa caaaatggta cggctttaat actgatttta gatttgagca gatgttaggg
     2221 caagagttaa tagaaagtgt gaagcataga tatggataaa ttaatactaa atttttatta
     2281 ctagttt
//
LOCUS       DAVKMO010000089         2162 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVKMO010000089 DAVKMO010000000
VERSION     DAVKMO010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.089"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            105..1721
                     /locus_tag="VW361_001978"
     CDS             105..1721
                     /locus_tag="VW361_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744952.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT          762 a          255 c          381 g          764 t
ORIGIN      
        1 acgaatttct ttttttgaaa tatatgttat tatataattt tggttttttc tattgtatat
       61 atgacaacta tgttcaatta aaatttagaa agtgagaaac tattgtgtat actattataa
      121 aatcaaatat aaaaaaattt agtttattaa cgatatttat tgttgctggt caattattgc
      181 taatttatgc agcaactatt aatgctctgg tgttgaatga attaattgcg atgaatttag
      241 agcggttttt gaaattgtca atctaccaaa tgattgtctg gtgtgggata atattccttg
      301 actgggtagt gaaaaattat caggttgaag tgatccaaga gtttaatcta gagattcgaa
      361 atagagttgc cacagacatc tctaactcta cctatcaaga atttcatagt aaatcatcag
      421 gaacatatct ttcgtggcta aataatgatg ttcagacttt aaatgatcag gcttttaaac
      481 aacttttttt agtaataaaa ggaatttctg gtactatatt tgcagttgtg actcttaatc
      541 actatcattg gtcattgact gtagccacct tgttttcatt aatgattatg ctacttgtac
      601 caaaaatctt tgcatcgaaa atgcgagaag ttagtctaaa tttaactagc caaaatgaag
      661 cttttttaaa atctagtgag actatattga atggatttga tgtgttagcg tccttgaatc
      721 ttttatatgt attgcctaag aaaattaaag aagcaggaat tttattaaag atggttatac
      781 aaagaaagac aactgtagaa acgttagcag gcgctattag cttctttctc aatatttttt
      841 ttcagatatc tctcgttttt ttaacaggct atcttgcaat aaaaggaata gtgaaaattg
      901 gtactattga agcaatagga gcactaacag gtgttatttt tacagcgcta ggtgaattag
      961 gaggtcaatt atcctctatt attggtacga agcctatttt tttaaaattg tattcaatta
     1021 atccaattga gtcaaataaa atgaatgata tcgaaccaaa tgaggtgaat agagattttc
     1081 cgttatatga agcaaaaaat atttgctata agtatggaga taaagaaata ttaaaaaact
     1141 taaatttttg ttttcaacgt aatgaaaagt atttaatttt aggtgaaagt ggaagcggga
     1201 aatctacatt attaaaatta ttgaatggct ttttgagaga ttatagtgga gaattgcgat
     1261 tctgcgggga tgatataaaa aaaacctcct atttaaatat ggtttcgaat gttctatatg
     1321 tagatcaaaa agcttatttg tttgaaggta cgattagaga taatatttta ttggaagaaa
     1381 attatactga tgaagaaata ctacagtctt tagaacaagt tggtttgagt gtaaaagatt
     1441 ttcctaataa cattttagat tattatgttg gtgatgatgg gagattactg tcaggagggc
     1501 agaaacaaaa aattacttta gctagaggcc taattagaaa taagaaaata gtattaattg
     1561 acgagggaac ttctgctatc gataggagaa cttcgttagc gattgaacgt aagatattag
     1621 atagagagga tttgactgtc attattgtta cccatgctcc gcatccggaa cttaaacaat
     1681 attttactaa gatatatcaa tttccaaagg attttattta agaatatagg ggagggaaac
     1741 atgagattct attgtgaagc ttatgaggta attactgaag agaaaaaagt atcatttttt
     1801 tatgtagatg agaaaccctt aaggtatctg ttatttgact atatatttct actagttcta
     1861 gctaaaaaaa atatcccaat cttatgaact gcaccccaaa agttagattt attctgtcta
     1921 acttttgggg tgcagttcat tttgcatagt tttggcattc atcctagata tccatataaa
     1981 atgtctgaga ttgttgaaat gtctaaaaaa atatcaaatc taaacgataa aaaagaattt
     2041 cacaaaaaga actgtgagtt gaggtttcaa gatagtgttc ttgataacat aaatagtgtc
     2101 ccgggtacaa ctcatttatt tagttgttta aatattcaaa cattagtaaa aattatttta
     2161 ta
//
LOCUS       DAVKMO010000090         2153 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVKMO010000090 DAVKMO010000000
VERSION     DAVKMO010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2153
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.090"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            48..920
                     /locus_tag="VW361_001979"
     CDS             48..920
                     /locus_tag="VW361_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9744953.1"
                     /translation="MIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQT
                     MLRNPLASPDIIGVTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKD
                     GFSAARLIILGIGFQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLI
                     VSIIATILVLFFNKRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPI
                     ACISFLAGPIALNIGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSP
                     YLIYLLIKMNRRNI"
     gene            920..1714
                     /locus_tag="VW361_001980"
     CDS             920..1714
                     /locus_tag="VW361_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744954.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHINS"
BASE COUNT          797 a          330 c          354 g          672 t
ORIGIN      
        1 catttttcat tttacttatc ggagatgaaa gttattcttt ttcaactttg attaaagtct
       61 taaatagtga aactgttcct ggagctagtt tttcgattat ggaaattaga ttaccaaaat
      121 tattagcagg aattatagct ggctggtctt ttggattggc aggatttatc tttcaaacta
      181 tgttaagaaa tcctcttgca agtcctgata taatcggtgt cacaagttct tcatctattg
      241 cagcggtctt ttgcatattg gtattaaaaa caaatagttt aactactgga attatttcaa
      301 taacttgtgg actaacatca tctttaatat tatttttact agctaaaaaa gatggttttt
      361 cagcagcaag actgataata ttaggtattg gttttcaagc tgtcacaaga gcaggcacct
      421 catttttatt gttgaaagta gcaagatatg aattacaaga agttatgaga tggctcagtg
      481 gctctttatc ttttacaaag ttagatgaca tacctcttgt tctaatagta agtattattg
      541 ctactatatt agttttattt tttaataaaa gactagaaat tattgaactt ggtgaagaaa
      601 tagcaatcgg acttggagca aatcccgagc tttcaaggct tgttttaatt ttttgcgctg
      661 tatctttaac tgctttttct acttcaatta caggaccaat agcttgtata tcttttttag
      721 ctggtcccat agccttaaat attggcaaga aaagaagccc aatattagct ggattggttg
      781 gaattttact agttttgtta tcagacatat tctctcaaaa tattttacca gctagatatc
      841 cagtaggtgt tgtaactggc ttgttaggtt caccatactt aatatactta ctaataaaaa
      901 tgaacaggag gaatatataa tgaaaggtct gtggtcaaat aatcttacct gcggttatga
      961 tgaaaaaata atcttggaaa atataaatat aaaaatacct gaagaaaaaa tatcagttat
     1021 tattgggtca aatggttgtg ggaaatcaac actcattaaa accttgtctc gacttataaa
     1081 gccattagag ggagaagtat tgcttgataa taaatcaatt aattcttata aagaaaaaga
     1141 tttagcaaaa cacatagcta tattacctca atctccaata atccctgaat caataacagt
     1201 agctgatctt gtaagccgtg gtcgtttccc ctacagaaag ccttttaaga gtcttggaaa
     1261 agatgacctt gaaataataa acagatcaat ggttaaggcc aatgttgaag atctagcaaa
     1321 taacctagtt gaagaacttt ctgggggtca aaggcaaaga gtatggatag ctctagccct
     1381 agcccaagat acaagtatcc tacttttaga tgagccaact acttacttgg atatctcata
     1441 tcaaatagaa ctattagacc tcttgactga tctaaaccaa aaatataaga caaccatttg
     1501 catgattttg cacgatataa atctaacagc aagatacgct gattacctat ttgcaattaa
     1561 agaaggtaaa cttgttgcag agggaaagcc tgaagatata ctaaatgata aactagttaa
     1621 agatatcttt aatcttgaag caaaaattat acgtgaccct atttccaatt cgcctctaat
     1681 gattcctatt ggcaagcacc atattaactc ttaataattg aatattggaa ttcatttaaa
     1741 agtcgcaaat tttgaactga ccctcaaaag ttaggccaaa aaactaacta aaggaggtca
     1801 gttttttaat ggcaaataca gcacagaatt taagataaaa ttagtaaaag aatatcatga
     1861 atgaaaaata ggatatagag aataacagca atattaaaaa gatcaggact gataataaac
     1921 aaaaagaaag tacaacgact agttcaaaag ctaaaacttc aagtaaaaag ttattcaaga
     1981 aaatctagaa aatactcatc ctacaaagga caggtaggaa aaatatcaga caacaaaata
     2041 aaaagaaata tttattaccg aaaaaaaggg gaaatcgagt caagtaccaa caggctcatc
     2101 tattccaaaa agatatttac tcgatggaaa aactcctaga attagtgcta caa
//
LOCUS       DAVKMO010000091         2018 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVKMO010000091 DAVKMO010000000
VERSION     DAVKMO010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2018
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.092"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            20..1045
                     /locus_tag="VW361_001981"
     CDS             20..1045
                     /locus_tag="VW361_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9744955.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1035..>2018
                     /locus_tag="VW361_001982"
     CDS             1035..>2018
                     /locus_tag="VW361_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9744956.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTM"
BASE COUNT          703 a          289 c          361 g          665 t
ORIGIN      
        1 atatgtttaa ggagttttta tgaaaaacaa attttttcta atagctattt tagctatgtg
       61 tatagttttt agcgcttgtt cttctaattc tgttaaaaat gaagaaaata cttctaaaga
      121 gcatgcgcct gataaaatag ttttagatca tgctttcggt caaactatat tagataaaaa
      181 acctgaaaga gttgcaacta ttgcttgggg aaatcatgat gtagcattag ctttaggaat
      241 agttcctgtt ggattttcaa aagcaaatta cggtgtaagt gctgataaag gagttttacc
      301 atggacagaa gaaaaaatca aagaactaaa tggtaaagct aacctatttg acgatttgga
      361 tggacttaac tttgaagcaa tatcaaattc taaaccagat gttatcttag caggttattc
      421 tggtataact aaagaagatt atgacactct atcaaaaatt gctcctgtag cagcatacaa
      481 atctaaacct tggcaaactt tatggagaga tatgattaaa attgattcaa aagccttagg
      541 tatggaaaaa gaaggtgatg agttaatcaa aaatactgaa gctcgtatat ccaaagaatt
      601 agaaaaacat ccagaaatca aaggaaaaat caaaggaaaa aaagtattat ttactatgat
      661 taatgctgca gatacatcaa aattctggat ttatactagc aaagatccaa gagcaaatta
      721 tttaacagat ttaggtctag ttttccctga atcattaaaa gaatttgaga gtgaagatag
      781 ttttgcaaag gaaatttctg cagaagaagc aaataagata aatgatgctg atgtaatcat
      841 aacttatggt gatgataaaa ctcttgaagc tttacaaaaa gatcctcttt taggtaaaat
      901 aaatgcaatt aaaaatggtg ccgttgctgt aattccagat aatacaccgt tagcagcctc
      961 atgcactcca acaccacttt caataaacta tactattgaa gaatacctaa atcttttagg
     1021 aaatgcatgc aaaaatgcga aataaaaaac aaataaacct aggcataatt tttgtaatct
     1081 gcctaggtct tcttattaca atatttttgt cattaaagct tggaacaaaa gaaattaata
     1141 tcagagattt tttagcagct tttggaatgg gcaatacaaa tgatgatttt attaaatcaa
     1201 ttatatataa aagaatacct agaactattt ttgcaatttt agcaggttct agtcttgcca
     1261 taagcggtgt attgatgcaa tcagttacta gaaacccaat agctgatcca ggtatactcg
     1321 gtataaacac aggagcaagt cttagtgtag taattggtct ttctttttta ggaatttcat
     1381 caagcataag ccatataagt tttgcaatca ttggtggctt agtaagtgca atttttgtat
     1441 acgcgattgc tgtaagcgga aaagcaggcc ttacccctat aaaacttgcc ttatcaggaa
     1501 cttgtgttag tatggcttta agcagttttg taagtttttt aattttaccg aataataacg
     1561 tcttagacaa atttagattt tggcaaatag gtagccttgg agcagctaca ttatcttcta
     1621 tatctacact actacctttt ataattttag gtcacttgat agctatattt atttcatcag
     1681 atttaaacgc tttagctatg ggtgatgaaa tggctgttgg tcttggagtt aatgttaata
     1741 ggataagatc acttgcaata attgcaagtg tgcttttatg ttcaagtatt actgcaattg
     1801 gtggacctat tggcttcgta ggtcttatag ttcctcactt ttgtggctta tttataagca
     1861 aagatatacg cacaatgacc atttcttcat cttttatagg tgcagagctc ttgcttatat
     1921 gtgatataat cggccgtatg ttaggtaaac caggtgaaat tgaagtaggg ataattactg
     1981 caataatcgg gggtccagta cttatttatg taactatg
//
LOCUS       DAVKMO010000092         1952 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVKMO010000092 DAVKMO010000000
VERSION     DAVKMO010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1952
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.093"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..225
                     /locus_tag="VW361_001983"
                     /pseudo
     CDS             1..225
                     /locus_tag="VW361_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
     gene            607..1100
                     /locus_tag="VW361_001984"
                     /pseudo
     CDS             607..1100
                     /locus_tag="VW361_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000452046.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1116..1328
                     /locus_tag="VW361_001985"
     CDS             1116..1328
                     /locus_tag="VW361_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744957.1"
                     /translation="MKLNKFNFLKENIRNLYSSGVIYLGLLISFIPPILVTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHAN"
     gene            1392..1844
                     /locus_tag="VW361_001986"
     CDS             1392..1844
                     /locus_tag="VW361_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744958.1"
                     /translation="MIYVLSNFLYAISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIV
                     AIVVNTILLVLFYFLLSYIFYLYKLKSGLVFGILVALLLFIPNILNTMMMNTSNDLFI
                     KAIELLPFYSLPVFVASNTMSISQYLVLITTIILLYFFTLKKSKKYSF"
BASE COUNT          655 a          260 c          330 g          707 t
ORIGIN      
        1 gatcgagttg aattttatgg ttcaggtttc cgtcattttg aaacctatat tgaagatttg
       61 catgatgcca aaggcaataa aatcgaccgc gctccaaatc caatggaact attgactatt
      121 aaagtcccat aacctgttca atcaggagac atggttcgtg cattaaaaga aggactcatc
      181 aatctttata aggaagatgg aaccagcgtc acagttcgtg cttaatgtag ttgtttagtt
      241 ttaaaaaatt atgcaaagct ccatatacaa cacttaaacg agattaaaga atggcgaaat
      301 cccttgatgc gcaagagatt agctgtcctt ttttattttt taagtgataa agtcggagct
      361 taggtatcaa agcctatcaa attaaacaaa gaagcgatgt cttagatatt ttgaaaaaaa
      421 ttaataagca aaaaactctc tattattttg ttgtagagag ttttttgtta ataaaatttt
      481 acaaaatgac atttatatat tgcattaagt tagatatatg atataatgtt gttaaaaaga
      541 ggcgcaactt tttaaactca ataagaatca aagagcaaac catgaatatt aattgaggaa
      601 taaaaaatgt aagttataaa tgtaagtaag cattatggtc attcaatcat tctcaaagat
      661 ataaattttg cacttaacaa gggtgaaatt gttggtcaag tagggagaaa tggagttggt
      721 aagagtacgt tgatgaaaat tcttgttcag aataatcaac cgacttcagg taatattata
      781 agcagtgata atgtattgaa gaaatttgtg agagggttct tttcttggag agcgggcttt
      841 tgacatttca aaaagtagga aaagatagtc ataatttctt gtttgagata gctttttcat
      901 cagctacaga tagagacatt ttcattacca aacaagaatt tggggatatt gttcaggaag
      961 agggactgag aattactatg tctgggaata ttcaaagtag tgagcttttt aaatttttta
     1021 acgaaaactc tattaaagta gttgattttg aaactaaaaa agagacgctt aaagatattt
     1081 atctaaatcg ttcaaaataa aggaaggtta taatcatgaa attaaataaa tttaattttc
     1141 ttaaggaaaa tataagaaat ttatattcat caggtgtaat atatctcggt ttgcttatct
     1201 catttatacc gccgatattg gttacattct ttattctaaa gactcaaggg acatcgcttg
     1261 gtattaagca tatttcaaac ttttatgcta tgctcggtat gttaatggct gttatacatg
     1321 ctaattgagt cattagtaga gatttttccc acaatacggt aagtttgttt tataatcaac
     1381 agaagaatcg gatgatttac gtcttgtcta attttctata tgccatctca gtttccatta
     1441 tttatgcttt gaatggcatt gtgttactag tcatagtaag taaattgggt attccaggtg
     1501 atttaggatt agattttata gtagctattg tagtcaatac aattttgtta gtcctgtttt
     1561 attttctatt atcttacatt ttctatttat acaaattgaa aagtggcttg gtatttggta
     1621 ttttagtagc tttactactc tttatcccta atatattaaa tacgatgatg atgaatacta
     1681 gtaatgattt gtttatcaaa gcaattgaac ttcttccttt ttattcttta cctgtatttg
     1741 tggcttcaaa tacgatgtct attagtcagt atcttgtgct aatcactaca atcattttat
     1801 tgtacttttt cactctcaag aaaagcaaga agtattcatt ttagtttcat ttagtattat
     1861 tttgcatacc taaaatacag taaaaaatca gtcatcttgg tatgctcctg ctttcactat
     1921 tcaacacgtt tttgacttat actaggctca tt
//
LOCUS       DAVKMO010000093         1916 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVKMO010000093 DAVKMO010000000
VERSION     DAVKMO010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1916
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.094"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            10..735
                     /locus_tag="VW361_001987"
     CDS             10..735
                     /locus_tag="VW361_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744959.1"
                     /translation="MLKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILGISGSG
                     KSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIPSLPVI
                     ENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAVIADSD
                     IIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILKDGKIF
                     KELHRPSGEELYKILEVQSTTEE"
     gene            738..>1916
                     /locus_tag="VW361_001988"
     CDS             738..>1916
                     /locus_tag="VW361_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744960.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQMSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKVQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELRVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     S"
BASE COUNT          618 a          250 c          350 g          698 t
ORIGIN      
        1 aaagattata tattaaaagt gaaagggctg tatcatcaat ttttactagg aaataataaa
       61 acgttgcaag tgctgaaaaa tgtttctctt tctgcttcga gaggagaatt tataagtatt
      121 ctaggaatta gtggttctgg aaagtcaact ttattaaaat gtatttctag tttgcttgaa
      181 ccaacaagtg gggaagtaat tttaaatgga atcaacccct ataaaatcag aaatgcaaaa
      241 ttgtcaagta taagacgtaa cgaagtatct tttatatttc aagcatacaa tttaatacct
      301 tccctgccgg taatagaaaa tatagcactt cctttgcgat tatcacaaaa aaaattaact
      361 attaaaaatg tagaaaactt actcaaaaga atgaagttta atgctggctt aaacgatttt
      421 gttggaactc tgtctggtgg agaacaacag aaggttgcta tagctagagc ggttattgct
      481 gatagtgata taatatttgc tgatgagcca actggggctt tagacagcgt ttctcgtgaa
      541 gtaatttttg aattattgag agagttagta ggggcgggta agtgtgtaat tatggtaacg
      601 cacgatatag aattggcctc gaaaactgat cgtgcattaa tattgaaaga tggaaaaatt
      661 ttcaaagaac ttcatagacc tagcggggaa gagttgtata aaatcttaga ggtacaatca
      721 actacggagg aatagagatg ctcagattag tttactatca atttttacat aataagaaac
      781 aatggttagg cgtttcacca gtaatttttg tttcgagttt agttatggga ttggctgtta
      841 atggggtaat taatgttgag aataattcgc aagtatttgt cggacttcca gatcctaaac
      901 caatttttat gtttccgata gtattcggag gagtaacatt attctttgtg ctctctaaca
      961 taataaatat gttggttgaa atttttagag atgattacga acttctggag gtgttgggag
     1021 caagtcgcct tcaactatca tttcttgtgg ggggacagat ttttatcatt tcctcgatta
     1081 ttagttttat tgcatatcta tgctctatat ttgttacgtc aaattattat tattttttac
     1141 aatacttttt cggggaaaat atattacctg atatccaatt tcaaatgagt gctgttggat
     1201 gtatcattac agtagtgttg atttcatttt tagcctttct aagtggttgc ttttatacgt
     1261 tcaagaagat tagaaatagg aagagttcta aaataaggca tgttctttca atagtaaaaa
     1321 gaatactgct attggctggt tttagtgtta tctggttgct ttctttgcaa caaattttcc
     1381 aagatagcac aattttagcg aaggtccaga taatattcaa tattgtaatc ttagatattg
     1441 tgattattta tcaattatct ccttttatac agtcatgttt tatcaaacta ctttctataa
     1501 ttatatttag aaataatttt atgttcattg tttcgaagtg gaatttacta tatcgtaagc
     1561 cttatataaa atctatcagt gctgcaatta caggagctat attactaatt tctagttttc
     1621 aaatgatttc tcagaatata ctatctcaat ttcaagatga cagtgattta gagctaagag
     1681 tggcatttat tgtctatgta ggagcaccaa ttttgatagt acttgcaaat attatttcaa
     1741 ttgcattttt gtcatcgcat caagaaagga ttgagattca gcaatttgaa attttaggaa
     1801 cttctaatta ccagatggtt aagattaaag ttggtgaggc tatatttttg acatttgtta
     1861 cttcattaat tgcattttta cttaacatta aaattatggc tttaatatac tactct
//
LOCUS       DAVKMO010000094         1901 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVKMO010000094 DAVKMO010000000
VERSION     DAVKMO010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1901
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.095"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..245)
                     /locus_tag="VW361_001989"
     CDS             complement(<1..245)
                     /locus_tag="VW361_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744961.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFD"
     gene            complement(273..1034)
                     /locus_tag="VW361_001990"
     CDS             complement(273..1034)
                     /locus_tag="VW361_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU9744962.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFVGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLQELLFGEWSQVEKEMLRVGEKRLNELLEK"
     gene            complement(1034..1510)
                     /locus_tag="VW361_001991"
     CDS             complement(1034..1510)
                     /locus_tag="VW361_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9744963.1"
                     /translation="MIGKNIKSLRKTHDLTQHEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
BASE COUNT          588 a          359 c          242 g          712 t
ORIGIN      
        1 ttatcaaaat tactaaaaaa aattgtctta tcaactttta ttttcttatt ttcaaaaaat
       61 atatcatata gttcatcttc agtaattttt ctatatttcg ttgcagtcca attagaaaat
      121 agcttgtaat cataagaaac aggtgtatgc aaatgaatta aagtcttgtg aaagctaccg
      181 aatttctctt tggaatttgt tagttcttga taaacagact ttatcttgtt attaaaccct
      241 ctcatttcta ttctcctaaa aatatcaatt gtttattttt caagtaattc attaagtctc
      301 ttttccccta ccctcaacat ctccttctct acctgactcc actccccaaa gagtaactct
      361 tgaagaacat ctgctgctga agttgtattt tcttttgaat catatacaca acttctatct
      421 cgttggtaaa tttgaattct ttcaaaaata gctagttctt ccaattgtcg tgtattatca
      481 actagatgat ttacaatgaa atcatgatgt tcttttggag ttgcgcgtgc ttgatttgga
      541 ttgataatgt acagttcttc ataacggata agagtactta gatacgacaa ttcaggcttt
      601 gtcgcaatta aggccaattg tacttcatat cccttatttt tcaagagttg tgctgttttc
      661 tttggaacat caactgttcg taaagttccc tcgatcaaaa gattgtatct caaactactc
      721 aattttgtta ctaaagactc taccattttt cctacaaaat ctttggtata ttctacactg
      781 tctttgccat attcttgctg cagttctaaa tagtgtggat gctgagaacg aaaactatca
      841 ccatctatga taacaatatt tccttgaaat tctttctgtt taatacgatg aattgtagtc
      901 ttaccggcac cactttgacc tccaagcaaa atcgctatag gttgtttact ggactttttt
      961 cctcttgtca gtgaacgaag attccttgct aaagcatgtt tgaattcact atcagtataa
     1021 tcttggattt ccattaagct accatccgct tttcagatat ctctaacata cgttcaattc
     1081 catccaaata gccgctatat ctctctattt catcaaaatt ttctactaaa tagatatttg
     1141 tctgaatcaa gtcagataga tcatcactca ttaaaatcca aggattagat tcatcatcaa
     1201 tgctaattcc ctgactatct tgataacgat agagtcgaga taatagatta gcacctcttt
     1261 ctttcacaat ttcaattttc aaagtcaatt cataatcttc aacaggattg agcattttat
     1321 cttctcctac aatatcgaca taagatacat taaacttctg acaaatgatg tctattaatt
     1381 cggtagagac tgaactcgtt ccattttcat aacgactcag actatttcgt gaaataccta
     1441 taatccgtgc aaattcgtgt tgtgttaagt catgtgtttt acgtaaggat tttatgttct
     1501 ttccaatcat ggcaaactcc tttattttta taaatccatt atagcataaa aaagcataac
     1561 gcaccaaaaa tggtgcatta tttcttgttt ttctatccta aactttactt ctataaaagt
     1621 cacctaaaga gccataaata tttattattg tattaatttt ttcgatgcgc aaacgatatc
     1681 tacaaataca tctataacga ttcacctttt aggattttta ttgtcaaaat tgcctttatc
     1741 tacaaagaca aaatgcttat aaaatagctt gaaatcaagg attatcacct ttttcgttgt
     1801 agcaacactc cacatgtgat tattaggcta ttagcaaagc gtatccaata cctcaataaa
     1861 gtgttgtttt tactgatatt ttaactatat tgtatagtct a
//
LOCUS       DAVKMO010000095         1882 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVKMO010000095 DAVKMO010000000
VERSION     DAVKMO010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1882
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.096"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(166..1797)
                     /locus_tag="VW361_001992"
     CDS             complement(166..1797)
                     /locus_tag="VW361_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU9744964.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
BASE COUNT          574 a          373 c          394 g          541 t
ORIGIN      
        1 caggacagtc aaatcgattt ctaacaatgt tttagaaata gaggtgtact attctagttt
       61 caatatacta tatatctgca gaatactctt tcagtttcat tcagcctagt cttgcttagg
      121 aaaaagtaag aagccatcca attatgatgg atagcttctt ggttcttaga tttgttctgc
      181 aaaaaccttt tcagcaaggt tcatagcgtg gtctgataca cgagtgtagt gtgagatgat
      241 gtcgataaag ttgaccccag cttgtgttga acattcgcct ttgttgaggc gtttgatgtg
      301 ggtttttctg agaacacgtt ctatcttatt gattgcttca tgacgttcta caagactgcg
      361 tgctttttca atatcattgt tttccacact atccagagca tctttgataa agtcactagt
      421 ttggcggtaa acttcctcta attctttcaa ggcggcatca gaaaattcaa catttttccg
      481 ttgaagatag tcagtcagat tgagtagagc ctccgtgtgg tctccaatcc gttccaaatc
      541 acgggaggaa tcaaggatat tggtgagcac ttcactttct ttttggctga gagcttcgct
      601 tgaaagggca atgagataac gtgttaattg ctcatcgatg gtgttaattg cttcttcggt
      661 tttatgccct ttttcagcaa ctttttcatc caagtcaatg atgtacttat aggaaaggtc
      721 aaaggcttta gcagcgtagt ttcctaagtg caagagctct ttcttagcat ttcctagagc
      781 gatagatggg gcctgtttga tgaaatgttc atcaagatat aagggttcgt attttacaac
      841 ctcgtcctct ccaggaataa tcttggttac aaagtaagcc agagctccga taaatggaaa
      901 ttggacaatg gtgttggtaa tattaaaggt tccgtgagca aaggcgatgg tcatttccgg
      961 tgctagattt agcgtagctt caaaccaatg aatcaggaca gtaaaaggaa ctagaaaaat
     1021 aacgcagaca actgttccga taacgttgaa ggcaacatga gctcctgcta cccgtttagc
     1081 tgcaatatta gcccctaaag aggcaatgat ggctgtaatg gttgtcccga tattgtcacc
     1141 aaatagaact ggcaaagctc cctgtaggtc aattagattg ccggcgtaga ggttttgtaa
     1201 aatcccaatg gtagccgaag aagcttgaat tagcaaggtc aagccagtac cgacaaagac
     1261 acccaaaaca ggatttttac ttagctcaat catatagtcc ttaaagacct gtaaatcctt
     1321 gagtggagcc attgcgccgc tcatgagatt gagggcaaaa aagataccac cgacaccaaa
     1381 gaggatgcgt ccgatattat tgactgtccg atttttcgta aaaaagagac agacggcacc
     1441 gataaagagc ataggtaggg catagttacc taatttaaaa ccgatgagaa aggatgtgac
     1501 agttgtccca atattagcac ccatgacaat cccgatagcc tgacgtaagg ttaagagacc
     1561 ggcactgacc aggccgactg taataactgt tacaccagaa ctagactgaa ttagagcagt
     1621 catcccaata ccaaccagaa ctccaaagaa aggattacta gtatatttgt caatgtaaaa
     1681 acgaaggcga tctccagcag cttgttgcaa accgtctccc atggtcttga tgctatataa
     1741 gaatagcccc agaccaccta aaaagtgaaa taaaatttcc tgccaattaa tggacatttc
     1801 tttttcctcc gaaaaataat cgcggaatat ctcctattct attttaaagg ataaaagtaa
     1861 atctaacaag tgttaatgtc aa
//
LOCUS       DAVKMO010000096         1788 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVKMO010000096 DAVKMO010000000
VERSION     DAVKMO010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1788
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.097"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            245..1648
                     /locus_tag="VW361_001993"
     CDS             245..1648
                     /locus_tag="VW361_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEU9744965.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQKLESALKQYNGP
                     YILSDKRWDEVPIYLRYGVFRPSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYLYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAASGFRSWRETFPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
BASE COUNT          644 a          226 c          355 g          563 t
ORIGIN      
        1 tcgttccaat atgtgcacgt tggaatgtta gtgcttatat ggggggaatc caaaggattc
       61 tcccttttta ttttaataag tctgtctagc tatagatata ttaagtttga tagaatttct
      121 tggagatttt gttatggatt ataatttcaa tttggagcat cctttctttt tcactaataa
      181 tgattatagt acagatacta gcataaagta ctaagtaagt ctgcctttta attggcacga
      241 agtaatgaat aatgatgagt gggtttatca ataccctatt ggaaaatttg ttgaaagaca
      301 agggtggaaa atacacatta gttcagagta taatagttca cacgaattgt tacaagatgt
      361 agcaaaaatt tgccatgaaa tgcgaattcc atttaaacat cttagtacag aagacaaatt
      421 tatcatgcga aacgggaaat tggttagtcg aggattttct ggtaaattta ttacatgtta
      481 tccaaatcaa aatgaattag agtcggtttt gcaaaagtta gaaagtgcct taaagcaata
      541 taatgggcca tatattttaa gcgataaacg ttgggatgaa gtaccaatat atctgaggta
      601 tggtgtgttt aggccgtcaa gggatgatga aaagaaggtt gctattgatg aattaattgt
      661 tggcgatgaa gttgttaaag atgaacgttt accagtattt aaaattccaa aaggtatagt
      721 gccccctgac tttttgaata aatggcttga caagaaagat aaaaaacagg gagactttcc
      781 ctttattata gataatgcaa ttagattttc aaacagtggt gggatatata atgctagact
      841 aaaagaagat gggaaaaaaa taattttaaa agaggctaga ccgtatacag gtctaggatt
      901 tgatggtact tattcttcag agagattagc ttcggagtgc aaagcactaa aaattctaaa
      961 tgaatggagc gagatgccta aaatatactt gtacggtaag atctgggagc acaccttctt
     1021 aggaattgaa catatgaagg gcgttccact aaatagatgg gttaccaata attttccttt
     1081 atatgaagtt gttgataaga ccaaagatta tctattgaga gtttcaaaga tagtagaaaa
     1141 actcatcgat ttaacgaata agtttcattc tgaaaatgta tatcatcaag atttacattt
     1201 aggaaatatc ttggttaagg atgaagatga gattagtata atagactggg aacaggctgt
     1261 cttttcgaat gatgaaaaag ttgtacataa agttgcagcc tctggtttta gatcatggcg
     1321 agaaacattt cccagtgaga tagattggta tggtattaga caaatagctc attatttata
     1381 catgccacta gtaactacat cagatttgac atacaactat gtaagtcaaa ccaggataga
     1441 aggaaaaaaa ctatttgagt ctttgggtta tacaagagaa catatagatt atgtagaaag
     1501 tttattgtca tatctagatt ctaaatgtcc acagattgag aatatttcca ggaaaaaagt
     1561 tttaaaaccc atgcatgaga ttagaactat cgagagtgag caagatatac aagattttat
     1621 tataaaagcc tttcttttag tgaactgata ggtattttct tagcaaacga taaagtttta
     1681 gggccgatac aatcaattgc ctattcatta aataagataa atacaaccat taaggaaacc
     1741 gtttttaaaa tacttaagtg gagagaagaa ttttatagac gctgaaca
//
LOCUS       DAVKMO010000097         1658 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVKMO010000097 DAVKMO010000000
VERSION     DAVKMO010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.098"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            72..527
                     /locus_tag="VW361_001994"
     CDS             72..527
                     /locus_tag="VW361_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9744966.1"
                     /translation="MQWQTQLSEKKANTDYIARYGVYAVIPNPEQKQIVLVQEPNGAW
                     FLPCGEIEAGENHQEALKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLY
                     EATPFKEVQKPLENFNHIAWFPIDEAIKNLKRGSHKWAIESWKKQHKID"
     gene            692..991
                     /locus_tag="VW361_001995"
     CDS             692..991
                     /locus_tag="VW361_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU9744967.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            1252..1575
                     /gene="tnpB"
                     /locus_tag="VW361_001996"
                     /pseudo
     CDS             1252..1575
                     /gene="tnpB"
                     /locus_tag="VW361_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          566 a          327 c          291 g          474 t
ORIGIN      
        1 gattatacca cattgtgtac tatttttggt tcatttcact ataataataa cgatactaga
       61 taatgaggaa aatgcaatgg caaacccaac tttcggagaa aaaagcgaat acagactata
      121 ttgctcgcta tggcgtatat gcagttatcc ctaatcctga acaaaaacaa attgttcttg
      181 ttcaagaacc aaatggtgct tggttcctac catgtggaga aattgaagca ggtgaaaatc
      241 atcaggaagc cctaaagcgt gagttgattg aagagcttgg tttcacagca gaaattggta
      301 cctattacgg acaagctgac gaatatttct attctcgtca tcgtgatacc tactactaca
      361 atcctgccta cctctatgaa gcaactcctt tcaaagaagt acaaaagcca ctagaaaact
      421 ttaatcatat tgcctggttc cctattgacg aggctatcaa aaaccttaaa cgtggtagcc
      481 ataaatgggc cattgaatct tggaaaaaac agcataagat tgactaatac tcaatgaaaa
      541 taaaattcaa accacgtcag cgtcgcctta ccgtactcaa gtatagcctg cggctagctt
      601 cctagtttgc tcttttattt tcattgagta taaatcaagc gactttattc aaaaagtgct
      661 ataatagaat tagaaaatcg gaggaaatat tatgaagctt atcaatacga caaactcaca
      721 ctcgcaactt gtaaaaagtc agctagaaag taccgatgca acccttgttg aggtttattc
      781 tgcagggaat acagatgtta tttttaccca agctccgctt cactatgaaa tcctcatctc
      841 aaacaaacac cgtgctattc gtgagcctga aatcgaaacc attcaagaat ttttcttgaa
      901 acgtaaaatt gataagacct ctgttgatga agccaatatc aagacactct actcagagaa
      961 attaattgga atttcaatcc caatcaagta agaaaattga gtaaaaactc gatttgagag
     1021 aaagtccaat aagtctttcc ataataaaac gcatagtagc aagagtttct acacccacta
     1081 ttatgcgttt ttatcatttt gaaatctact gctaatcaat gaagaagcaa agatcaaact
     1141 aggcagctag ttacaagtta cgtaagcgcg tcataacaag gtatctatcc taattcccca
     1201 acttccagta tactagataa aaaataatta tcggaggaaa ggtattgtac tatgataatt
     1261 caactaagtg atttaggtca agttcacctt gtttgtggca agacagatat gaggcaggga
     1321 atagactcat tagcctatgt agttaaaacc cactttgaat tggatccttt ctccggtcaa
     1381 gcctttctct tttgtggtgg acgtaaagac cgctttaaag ccctttactg ggatggtcaa
     1441 ggattttggc tactatataa acgctttgag aacggaaaac tgacttgacc aagtacagaa
     1501 aaggatgtca aagctctcac accagaacaa gtagactggc ttatgaaggg cttttctatc
     1561 actccccaaa tatagtggat ttaaactaga atagtacacc cctacttcta aaacattgtt
     1621 agaaatcgat ttgactgtcc tgatcaattt gtcctgtt
//
LOCUS       DAVKMO010000098         1656 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVKMO010000098 DAVKMO010000000
VERSION     DAVKMO010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1656
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.099"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..883
                     /locus_tag="VW361_001997"
                     /pseudo
     CDS             1..883
                     /locus_tag="VW361_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            876..>1656
                     /locus_tag="VW361_001998"
     CDS             876..>1656
                     /locus_tag="VW361_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9744968.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSYKNIEVIIID
                     DNYSNVNLRNKIIHQFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLN"
BASE COUNT          626 a          158 c          321 g          551 t
ORIGIN      
        1 aaaatatttt aaaattatta aaaatccaac ttatacactg tcatggctac tcaactaatt
       61 attttttata tatgttaaaa aaacttgaca agaatggatt tggaaaggtt aagacagtga
      121 taacatgcca tggatgggtt gaatataact taaaaaagaa attcttgact tattttgatt
      181 tttggacata ttctatggga gatgctttta tttgtgtatc tgaaactatg aaaaaaagat
      241 tggagagtat aataaaaaaa taagaagata gttgcaataa ataacggaat taatgtatca
      301 aatagcgatt tagatgtagt aggtgttcaa gactttaaaa aagaattttg tattccaaat
      361 aacaaaaaaa tcatttgtta tgttggaagg ttggatccag aaaaaaggcc ggatagattc
      421 cttgaatttg cagaaaaatt atttttagtc agagaagatg tgatttttat tatggctgga
      481 aatggtagta tgtgggctgc tttgaaagaa aaaatttgcc atttgaaatg tagagataat
      541 ttcaggttac ttggtgaaat ctatccagct actatagttt accaaatatc ggatttattg
      601 tatattcctt ctgatacaga aggaatacct atgtgtgttt tagagtcaat gtcacaagga
      661 actccggttt tagctagtaa tgttggcggg ttaagtgaaa ttattgaaca tagggttgat
      721 ggatttttat ttgagaagga agatgttgag ggagtgtgtg cttgtgctaa ttttttactc
      781 aatgattctg agtatttgaa atatataggt gagaatagta aatcaaaaat aagaaaacat
      841 gagagtatat gatgaattat tagagaagag tagtcatgga taggaatata gatcaagaat
      901 tagtaagtat tataatacca acacataata ggtatgaatc tctgattaga gctgtgaaaa
      961 gttgtttaca tcaaagttat aaaaatatcg aagttataat tattgatgat aattatagta
     1021 atgtaaattt aagaaataaa attatccatc aatttggcta taccaatcat agaattaagt
     1081 taattttaag taatgaagat ttaggtgcaa ctaatgccag aaacataggt atcaaaaatt
     1141 ctagaggtaa gtatatatca tttttagacg atgatgatga atatatgcca gatcgaattt
     1201 taaagttgat ggcttgtttt aaaaagagta gaatgaagaa tttagcttta gtttatagtt
     1261 atggaataat aatttatcca aatggtacac gagaagagga gaagaccgat tttgttggaa
     1321 atcccttgtt tgttcaaatg gttcacaata tagcaggtac gtcattttgg ttgtgtaaaa
     1381 aagaggtgct agaattaatt aatggttttg agaaaataga ttcacatcag gacggtgttg
     1441 ttttattaaa actacttgct caaggatacc aaattgatat agtgcgagaa ttcttggtga
     1501 attactacgc tcacagtaaa gaaaacggta tcactggagt gacacaaaaa acaattaatg
     1561 cagatgaaga atattataat tactgtagga aatattttaa tttattgagt ttcaacgaga
     1621 gaatattggt tacaaagaaa tattattctt taaaca
//
LOCUS       DAVKMO010000099         1614 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVKMO010000099 DAVKMO010000000
VERSION     DAVKMO010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1614
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.100"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..753)
                     /locus_tag="VW361_001999"
     CDS             complement(<1..753)
                     /locus_tag="VW361_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744969.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLIQNQSKVDLDIFYKVLPLLYKEKY"
BASE COUNT          615 a          281 c          198 g          520 t
ORIGIN      
        1 atatttttct ttataaagca aaggtaaaac tttataaaaa atatctaagt caaccttact
       61 ctgattctga atcaagtagg agtcaagcaa attttcaaaa atagctaaca atatgattgg
      121 tgtaaagttt ttgtattcac atgtcaagta ttctgagtat cgtgcagatg atatttcttt
      181 tatataactt tttgaaagca agattttttc aaattcatca tctattatta atcttctatt
      241 tccaatccaa acggtattac cacccaaata agattgtgca aatagcaata tgtaagaaaa
      301 tatgaacgta aatactgaaa gaggtagaat tctatgcgta aaaaaataga cgataatagt
      361 agccaggagt aaagatatct ctcgtgacaa tcgaattctt ttcagcatct tttttaacag
      421 tccgtaaggt tgtccttggc aatattcttg aactaaatta atcggaatga catctctcac
      481 catttctgga aagtagagta agtttatagg ttgaaatctc cagctcccat cataagtaaa
      541 tggatataga accaaatact taaaagattt ttttcttata aacttaatta tcacaatatg
      601 aatgactgtt gcaatgaagt atattaaata taaaagtaaa accgccatca atatacttac
      661 aaaaatcccc ttggactcaa tcaatggaaa ataaaatatt gcaactagaa gcgaataaag
      721 tcccgctaat aaatatttct gatcatcttt cattcaaaac accatattat ttactaagaa
      781 tacatcaata caatagagca actctgtaag tcaatatttg ataaagcaaa gctttaaccc
      841 cttccccaga cgttagcttt tcttcaaccc actacagttg acaaggagcc caaattattg
      901 ataaaaactt tagtcatcat cgtctctata aaaatatttt ctatacactc ttgataatac
      961 caaaattaat gccaatatca taccaagagc tataataata gaatttatta gatttatttt
     1021 agtatatcca atcactagtc caataattgg actagcagac atgcttagat ataataaaaa
     1081 taacaaaaaa tgaatttcac caattcctgc aaaaaaatgt ttcatagcta tagttttacg
     1141 cccataaata cccatcaaat ttaccgtcta cgatatctaa accatatgca atggctcctc
     1201 ctaatgagaa gacttcagca acagtagccg caatattaag agcattagta atagttgcca
     1261 tactaactcc accaatatat cttgttatag cacttagtta cctagataag atatccttta
     1321 gcttgcttcc aaaatttaag tctgcaccta taatatgagt tcatattagt actgctaaat
     1381 cctatctata gtaatgtcaa acacctaaat aaagtcatct ctccaattca ttcaagaaat
     1441 gaagaaaggc aaaaaatctt taaaataaga aaaatgcata ttatcaggtg ttcaaaaata
     1501 ttgatgatat acgttatata gatagaaaga tttactcaat ctcattttca aattgagttt
     1561 tttcccagcc tcatttttaa tttatatctt caatagaatc taatgaccga gcta
//
LOCUS       DAVKMO010000100         1576 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVKMO010000100 DAVKMO010000000
VERSION     DAVKMO010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.101"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            27..1373
                     /gene="gdhA"
                     /locus_tag="VW361_002000"
     CDS             27..1373
                     /gene="gdhA"
                     /locus_tag="VW361_002000"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU9744970.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWNYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          477 a          305 c          329 g          465 t
ORIGIN      
        1 aaatatgaca ataaaaggag aacgatatga catctgctaa agaatatatc caaagcgtgt
       61 ttgaaactgt gaaagctcgt aacgggcacg aggctgaatt cctccaagct gttgaagaat
      121 ttttcaacac tttagaacct gtatttgaaa aacaccctga gtatatcgaa gaaaatatct
      181 tggcacgtat tactgagcct gagcgcgtga tttctttccg tgttccttgg gttgaccgtg
      241 atggaaaagt tcaagtaaac cgtggttacc gtgttcaatt caactcagct gttggaccat
      301 acaaaggtgg acttcgtttc cacccaactg taaaccaagg gatcttgaaa ttcctcggat
      361 ttgaacaaat ctttaaaaat gtcttgactg gacttcctat cggtggaggt aaaggtggat
      421 cagacttcga tcctaaaggt aaaacagatg ctgaagtgat gcgcttctgc caaagcttca
      481 tgactgaatt gcaaaaacac atcggaccat cacttgacgt acctgctggt gatatcggtg
      541 ttggtggacg tgagattggt tacctttacg gtcaatacaa acgtcttaac caatttgatg
      601 ctggtgtctt gactggtaaa cctcttggat ttggtggtag cttgattcgt ccagaagcaa
      661 ctggttacgg tttggtttac tatactgaag aaatgctcaa agctaacggt aacagctttg
      721 ctggtaagaa agtcgttatt tcaggttctg gtaacgttgc tcaatatgct cttcaaaaag
      781 caactgaact cggtgcaact gttatttctg tttctgactc aaatggttat gtcatcgatg
      841 aaaatggtat cgacttcgat cttttggttg atgttaaaga aaaacgtcgt gctcgtttga
      901 ctgagtatgc agctgaaaaa gcaactgcaa cctaccacga aggtactgta tggaattacg
      961 ctggaaacta tgacattgct cttccatgtg ccactcaaaa cgaaatcaac ggtgaagcag
     1021 ctaaacgttt ggttgctcaa ggcgttatct gtgtatctga aggtgccaac atgccgagcg
     1081 accttgatgc catcaaagtt tacaaagaaa atggtatctt atacggacct gcaaaagctg
     1141 ccaacgctgg tggtgtagcc gtttcagctc ttgaaatgag ccaaaacagt cttcgcctct
     1201 catggactcg tgaagaagtt gatgaccgtc tcaaagacat catgacaaac atcttcaaca
     1261 cagctaaaac gacttcagaa acatacggtc ttgataaaga ctaccttgca ggagctaaca
     1321 ttgctgcctt tgaaaatgta gcaaacgcta tgattgccca aggtattgtt taagatttat
     1381 ttgcttaatc ctcaatcact acgattgggg atttttagtt gagttagaca gttgggaaat
     1441 tctaattaaa tgaaataaaa actgaacaaa ttgattgcgg aattcaaacc aatttctaac
     1501 atatttctag aaattaattt gacttttcta atcgatttgt tcatatctta tttcaattta
     1561 ctatacttac ttaacc
//
LOCUS       DAVKMO010000101         1496 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVKMO010000101 DAVKMO010000000
VERSION     DAVKMO010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1496
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.102"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            213..1010
                     /locus_tag="VW361_002001"
                     /pseudo
     CDS             213..1010
                     /locus_tag="VW361_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1045..1254)
                     /locus_tag="VW361_002002"
                     /pseudo
     CDS             complement(1045..1254)
                     /locus_tag="VW361_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1420..1493)
                     /locus_tag="VW361_002003"
     tRNA            complement(1420..1493)
                     /locus_tag="VW361_002003"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1457..1459),aa:Asn,seq:gtt)
BASE COUNT          513 a          299 c          228 g          456 t
ORIGIN      
        1 cattcactat caattcctga attgttaaaa taccagcctc aacaagataa aaataggaaa
       61 agttgacaaa atagaaacaa atttgttacc taaatttcaa acaattaaag ttctaaaaag
      121 accgccttaa aacttttggg taaatcctat tagaactata atatttttat ataggtatta
      181 tggttctgat tttctagtat aaaaaaattc aaactagaat tcttcttaga aaaggccgtt
      241 ttaagtgcta tcattgctca aaaatggagc tcgctgagac ttctatcgtc aagaagaatc
      301 atcaaattcc ttgtatcatc aaccaaaaga ttgctcagaa gctaattaaa aagacttcta
      361 tgaccgacat tgatcatcag ttgtctattt caacttcaac tgtcattcgc aagatcaatg
      421 attttcactt tgagcatgat ttttcgcgtc ttcctgagat tatgtcctag gacgttgaaa
      481 cagtccgggg agtgactgtt tcaatcggga gatggagatg agctttattg ctcaagactt
      541 tgataagctc aatatcataa ctgttcttga gagcagaaca caagccatca tccgaaatcc
      601 catgaataca aggctatcaa gcgatactga aagctcattc aacaagatag tcagaaactg
      661 agtgataaac gattttatcg ccctactttt cgtatgcact tgactaataa agaaattcta
      721 gataaacttt tgagctattc cgaagacttg aaacaccact ataatctcta ccagctcttg
      781 cttttccacc tctttttcag actctgttta aaaccttcct caaagataaa gagaaaatcg
      841 tcaacgccct tcaattacct tattccaacg ccaaactgga agccaccaat aatctcatca
      901 aacttatcaa gtacaatgcc tttggtttta ggaactttga aaacttcaaa aaagaaagga
      961 cgaaatttgt cctttctaga tcttcgcttt cttcaaccca ctacagttga caaagaaccg
     1021 aaaaatgtct cgcctctaat atagtcaatt gaaacaagaa caagacaaaa gagcctcata
     1081 aaaggtattg caacttggta ataccttttt ggggttcttt ttgatatgaa cccatgtttt
     1141 ctcaatagga ttgtactcag gtgagtaggg aggaagaggt aaaagtttat gcccaaactc
     1201 ttcacacaag agttctagct tacccattct atggaatctt gcattgtcca taatatagta
     1261 gattgaaact agaatagtac acctctactt ctaaaacatt gttagaattc gattttactg
     1321 tcctgatcga tttgtcctat tcttatttca ttttactata acacgaaata gattattatt
     1381 acataacaaa aaagaggtct aaacctctta actaaattac tccgccagta ggactcgaac
     1441 ctacgacatc atgattaaca gtcatgcgct actaccaact gagctatggc ggatta
//
LOCUS       DAVKMO010000102         1449 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVKMO010000102 DAVKMO010000000
VERSION     DAVKMO010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1449
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.103"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            2..>1449
                     /locus_tag="VW361_002004"
     CDS             2..>1449
                     /locus_tag="VW361_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEU9744971.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVDAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHE"
BASE COUNT          552 a          168 c          256 g          473 t
ORIGIN      
        1 tatggaagaa aattataatt tatctataac tcaaataaag aattctatta aagaaaattc
       61 cttagttttg tttgttgatg caggaatatc agctaattct aatctaccaa cttggggaga
      121 attgattcaa tcattaaaaa aagaattgaa cataccagaa gaaagaacag atagtccact
      181 gagaattgct cagtattatt atgatacttt tgggaaaaat cagtacacaa agaagataga
      241 agaaattttc tttaagaagg gattgagtaa accaaatgag ttacataaat taatagaaaa
      301 aattgcacca aaacatatta ttacgacaaa ctatgattca cttctggaga gtcaatttga
      361 aagtggcttg ttaaagtaca atgtagtcgc tgaggataaa gacatccctt atacgagttc
      421 ggaaagatac ttgattaaaa tgcatggtga cttcagtaag aaaaatattg ttttgaaaga
      481 agatgattat ttagactatc atttgaactt cccaatgatt tctactttaa tccagtcatt
      541 gataatgaat catactctat tgtttgtggg gtattctcta agtgattcga cttttaattc
      601 aatttttaga atgattcaaa atacatttaa attggatgct aaaaatgctt atttttatac
      661 tcccgaggaa ccgtctatga tcattcgaga gtattataag aagcaaggaa ttttcattat
      721 ctctaatgaa gagaatctag gtcaggagac atcagaaaaa cagaacaaat tgtattgcag
      781 gacaaaagat tttttagagg ttctatcaga aaaccgaagt caagatgtaa ataatgctga
      841 tgatttatgg aatcaactgg cttttttaga tagacttagt tttattgatg cgaaagattt
      901 ttctagatat tctgatttaa agaaaagggc tttaaactgg gatgatgagt attgctggtt
      961 tggaaatgat caattaagat ttgaaattga tggtcatgaa gaattacgaa ttatggtatc
     1021 taaaaaatct ttattaaatc gctttctaga tatggagatt ggtgagccta gggatttaaa
     1081 ggggaatcga ttcttaagta aggcttttaa gttgtatgaa gaaaaacaat attctttagc
     1141 aaaagcaaaa tttagagaac tagctaatat agcatttcgt cagaaagact attttaattt
     1201 cttagtttgt gaatttaatt ttcagcaaat tcaaataatt gatagatacg aaaaaacacc
     1261 tagttatgca gagccacttt atgatggaga attaagcgaa ttaacagaac aaattcttaa
     1321 ctcggttaca ggagatgaga aaaagattat agaatttttt agagattcaa tccttaactt
     1381 caatttttta tatagaaaat tagaaactat taatgaatta tttgatgaaa ttcgtgaaga
     1441 gcatgaaag
//
LOCUS       DAVKMO010000103         1271 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVKMO010000103 DAVKMO010000000
VERSION     DAVKMO010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1271
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.104"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            99..818
                     /locus_tag="VW361_002005"
     CDS             99..818
                     /locus_tag="VW361_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9744972.1"
                     /translation="MQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISI
                     VSQGDDNSYYGNKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTEIP
                     WVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPATH
                     NEAIISIFPYAKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPISNHE
                     EMKRIISKVDLLFQKVSQLFE"
     gene            complement(766..>1271)
                     /locus_tag="VW361_002006"
     CDS             complement(766..>1271)
                     /locus_tag="VW361_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9744973.1"
                     /translation="NTGLSYKKGDLSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQF
                     ISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIFQLTPFESSEIISKF
                     LLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFEEQELITQKVEKLFE
                     KVNQLWK"
BASE COUNT          478 a          193 c          195 g          405 t
ORIGIN      
        1 tagaaaaagt agatgaatat gctgaaagtt ataatagact agaacagcta gataaagaat
       61 ttccagataa actaaaaaaa tctattcttc aatatgctat gcaaggaaaa ttagttgaac
      121 aagacccaaa tgatgaatca gtcgaagttt tacttgaaaa aatacgagca gaaaaacaaa
      181 aactctttga agaaggcaag attaaaaaga aagatttgga catttctatt gtttcccaag
      241 gagatgataa ctcttattat gggaataaag acgaaacaac ctcttatcct atatatgaaa
      301 tcccagaagc atggagatat attaaatttg ctagcctagt taacttcaga ataggaaaaa
      361 ctcctccacg cagtgaagct actttttggg gaactgaaat accttgggta tctatatcag
      421 atatgcctat atctggttat gtaactaata cgagagaatc tatttctaaa ttagcattaa
      481 aatcaaagaa aatagacatt tcacctaaag gaactttatt aatgagtttt aaattatcta
      541 ttggaaaagt tgccatattg gatattcctg ccactcataa tgaagccatt atatcgatat
      601 tcccctatgc taaagaaaat attatcagag attacttaat gatatttttg ccacttatct
      661 ctactttagg tgattcaaaa gatgctatca aagggaaaac attaaatagt accagtatct
      721 ccgaattatt aatccctatt tctaatcatg aagagatgaa aagaatcatt tccaaagttg
      781 atttactttt tcaaaaagtt tctcaacttt ttgagtaata agttcctgtt cctcaaaagg
      841 agctaacgga attaatagct cgctcagtgt agttttagga atattatata aagcttgacc
      901 tgatagttta gttattgctt tcaattgttt ataaaataac ggagaagaca agttaaataa
      961 tagaaatttt gaaataatct ctgaactttc gaatggtgtt aattggaaaa taaatccacc
     1021 agccacaaca ccatcatagt ctttatcgat tcttgcaaac tttccaatat gttctaaaga
     1081 ggttgataca ggtgttatta gctgattatg ttttaaataa acttgctcag aggagatgaa
     1141 ttgtgtatca atgtagtaat cattatccaa cagagaaaat tctaaaggct taatattacc
     1201 accacgtata attctaacac ctttattatt aatgcttaaa tcgcccttct tgtaagaaag
     1261 acctgtattt a
//
LOCUS       DAVKMO010000104         1155 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVKMO010000104 DAVKMO010000000
VERSION     DAVKMO010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1155
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.105"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(555..740)
                     /locus_tag="VW361_002007"
                     /pseudo
     CDS             complement(555..740)
                     /locus_tag="VW361_002007"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          360 a          151 c          203 g          441 t
ORIGIN      
        1 tttttcttaa ttagctcgta tctataggat gatactgaaa atcttcttgt tgctttaaat
       61 cacaatcgaa aaattctgtt tttcatctta gaaaagaatg tttagaaatg taaaatgaac
      121 cttttttctt atccgaaaac cttactaaag tatataattt aggaagtcaa ttctgtatga
      181 taatgtttgt actatcgtcg agtttttgct tgattgccta acgagataaa ttttagaaga
      241 gttttcggtg tgatttgaca agtttctgac tggaaggata gttacactag tattgtttat
      301 taaaatgagc agatagagaa aatttggaat ctatttgctt attatcaatc gttttttagc
      361 ttatttgtct tagattggta tagaactgag ctatggatta atcttcttgt atcttatcct
      421 gttcctaaat atgttggtag aaaaatgaag cagttgttac gagtgtctgt attggaaaaa
      481 aattttgtct atacaattct ttaaatgata tgaagactag gaatgccaaa acactgacat
      541 atttcgttta aagcctatcc agtctcttca attgtatttg tagaaatgct atcagtaata
      601 tattcgcgaa cactatgatt tacaacagtg tggtcgtaca tctttgtaac tttattatac
      661 aacaaccatt tacaggtgta aagttgagca gtgtctttag taaatttagg gacttgtttt
      721 gtcatagttt tgatacctgt attcgttgtt tcatgagtat ttgacgtttc ttttcatgta
      781 ggcatttcaa caattagaat gatatttttc cgaggatgag cttatatatt gtgacttttt
      841 agagttatga tgcctcttga tttgactatc gctatcaatt tcatccactt ttacagtttc
      901 atggttttat gaaccgaaac atctaggtac aggttttagc atcaattgat tgtttttgag
      961 ccatatgaag ttgaaacgtg gagatgcttt tcttgtgata acgccctatt caaagaggaa
     1021 taaccgtttt tggagagagt tcagtactat gtggcgctaa atactatatg taaaacatat
     1081 attaaacaag atttaactaa ggagaattgt aaaaacaaaa atgagaattt catataaagt
     1141 ttattctagg agtat
//
LOCUS       DAVKMO010000105         1088 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVKMO010000105 DAVKMO010000000
VERSION     DAVKMO010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.106"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(<1..200)
                     /locus_tag="VW361_002008"
     CDS             complement(<1..200)
                     /locus_tag="VW361_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEU9744974.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDT"
     gene            complement(213..961)
                     /locus_tag="VW361_002009"
                     /pseudo
     CDS             complement(213..961)
                     /locus_tag="VW361_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
BASE COUNT          387 a          203 c          117 g          381 t
ORIGIN      
        1 aatgtatcaa aaaaagtaat atttaagtta ttctcgcaaa aaaacttcat aagctcttca
       61 tttttagatg gaagaatgcc cttttttaaa ttatttattt ttacagaatc tatatcatat
      121 gcaacaactt tatatttaga tgcaaatagt aacgcgtagg ccagcccaac atgccccaaa
      181 ccaattactg ctatattcat aaaactactt ccttatttct taatccaaaa tctaatagaa
      241 taagctgccc cattccttaa atacaactct ttaatattgt ttaaaagttt ttcaactgat
      301 ttccagatta tcaaaatctg agatttatag cacaatattg atgatattct atcaatataa
      361 ttttttcatc aagttcctct tgatacattt ttaattcttt agtttttccc atataactaa
      421 ccatactact atcacttaca tatgggaagt cctcataata tattacttta taacgcataa
      481 attcaagcac ccttccaata ctattcacaa aaacatgatc aacatggtca ccaagtgaaa
      541 gcggacaata tacgacacat ttgtcgtcta aatgcattaa cagctctttt atgatatcat
      601 tctttaatgt gtcctcattt tttaattcac tatagatatg acggtataga aaattgccat
      661 ttctatcttt cctatagaga cattcatagt acgataagtg tctaaaatca cattgtagac
      721 gttcacaagc taacctgtct tctttcttcc tttcttcaat cggatatttc ccaaggttac
      781 acaacttatg aaattgctta gcagagggct gtagctgttg gctcaaaggg taaccagaaa
      841 atatagtaat aacaagtaca atttctcctt ctgaagttaa ttttgaaata taatcaccac
      901 aggaaaaaat tgcgtcatct aaatgtggag ataaaaagat atacttagta ttgttactca
      961 taaccattcc ctctacaatt tatctaaaaa ctcactaagt gtctgattaa attccacatc
     1021 atcaaaaaaa ttcaccttat tcttaataat gaatatttcg ttaaataaac atatatataa
     1081 atatttca
//
LOCUS       DAVKMO010000106         1075 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVKMO010000106 DAVKMO010000000
VERSION     DAVKMO010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1075
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.107"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            468..>1075
                     /locus_tag="VW361_002010"
     CDS             468..>1075
                     /locus_tag="VW361_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9744975.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRW"
BASE COUNT          313 a          181 c          227 g          354 t
ORIGIN      
        1 gcttttttct ttttaaatat tgattgtttc taaaagttct agtaatattg ctatttctca
       61 tttttccaaa tatgttattc aacttattag ctacgtctct attcatattt gggtataaaa
      121 caaaaaatca attctaacag ttttatatca gaataataaa taaaaaagcg atattctaga
      181 ctgtatcaat ccttttccat tataggagca acagagtggg agtagtcatc taaggactaa
      241 tttatatatt tttacgagtc agtatcttgg gatactggtt tttacttttt tagacttttt
      301 gactacttgt taaaactggg gtaattttcg actgtttaat agttattatg caaagtctaa
      361 aagattagaa ttgtcaaaac aatccgtcta ggcttgattt tatcctttat ttactataaa
      421 atgagaagga aaaatgtcaa acttttatat tgcaaatagg agaaattatg acaaaaacat
      481 taaaacgtcc tgaggtttta tcacctgcag ggactttaga gaagctaaag gtagctgttc
      541 agtatggagc agatgctgtc tttatcggtg gtcaggccta tggtcttcgt agccgtgcgg
      601 gaaactttac tttcgaacag atggaagaag gcgtgcagtt tgcggccaag tatggtgcca
      661 aggtctatgt agcggctaat atggttatgc acgaaggaaa tgaagctggt gctggtgagt
      721 ggttccgtaa actgcgtgat atcgggattg cagcagttat cgtatctgac ccagccttga
      781 ttatgattgc agctactgaa gcaccaggcc ttgaaatcca cctttctacc caagccagtg
      841 ccactaacta tgaaaccctt gagttctgga aagagctagg cttgactcgt gtcgttttag
      901 cgcgtgaggt ttcaatggaa gaattagctg aaatccgcaa acgtacagat gttgaaattg
      961 aagcctttgt ccatggagct atgtgtattt catactctgg acgttgtact ctttcaaacc
     1021 acatgagtat gcgtgatgcc aaccgtggtg gatgttctca gtcatgccgt tggaa
//
LOCUS       DAVKMO010000107         1054 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVKMO010000107 DAVKMO010000000
VERSION     DAVKMO010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.108"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            84..266
                     /locus_tag="VW361_002011"
     CDS             84..266
                     /locus_tag="VW361_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU9744976.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            276..629
                     /locus_tag="VW361_002012"
     CDS             276..629
                     /locus_tag="VW361_002012"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU9744977.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYETKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIENKKQG"
     gene            637..>1054
                     /locus_tag="VW361_002013"
     CDS             637..>1054
                     /locus_tag="VW361_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU9744978.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKF"
BASE COUNT          435 a          130 c          171 g          318 t
ORIGIN      
        1 cgaattagaa agaaaaaatc gaaaaattag ctaagaaata ttctgataac ttaaacatca
       61 aagttcaaga gagagttcgt gaaatggcaa atgataataa gagccattat ttgatataca
      121 gagttttagg tatttcattt gaagaaggag aaaatatcga tttgtatcaa aataaaggtc
      181 gttttttata caaatatgct ggttcatttt tagaagaagc tgcagtacta tcctttaacg
      241 aaaaatttgg tacagaaaat acttaaaaag ttaacattcc taattctgaa agtacaaaac
      301 ctaagacttt tgaaattgat tgtttagtcg gagaaaaaca cgcatacgaa acaaaatggt
      361 gggatgcaac tacagatgga gaccatataa ctaaagaaca cactagaata aaagttattc
      421 ataacaaagg atatatacca attcggttaa tgttctacta tccaaataga actcaagcta
      481 taaaaattca gcaaacttta gaaacattgt ataacggtat tggagggaaa tattattatg
      541 gagattctgc ctgggaacat ttaagagcag tgaccggtat tgatttactt agtattctaa
      601 cagatattga aaataaaaaa caggggtaaa atcaaaatga cagtattaaa aggagataac
      661 ttagaaatat taaaaactat tgaatcctca agtattgatt taatctatat ggaccctcct
      721 ttctttacac agaaaaccca aaaattatct aataacaaaa atattatgta ttcattcgaa
      781 gatacgtgga cttcgattga ggattacaaa gaatttttgt ctgtaagatt agaagaatgc
      841 aaaagagtgc taaaaaatag tggcagtatt ttcgttcatt gtgataaaat tgcaaatcat
      901 catattagat taattttaga taatatcttt ggagcagata tgtttcaaag cgaaattata
      961 tggaactata aacggtggtc taattcaaaa aagggattat tgaacaatca tcaaaacatt
     1021 tacttttatt caaagtcaaa agattttaaa ttta
//
LOCUS       DAVKMO010000108          846 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVKMO010000108 DAVKMO010000000
VERSION     DAVKMO010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.109"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            complement(296..607)
                     /locus_tag="VW361_002014"
     CDS             complement(296..607)
                     /locus_tag="VW361_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744979.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(622..>846)
                     /locus_tag="VW361_002015"
     CDS             complement(622..>846)
                     /locus_tag="VW361_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEU9744980.1"
                     /translation="NQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIKVPQ
                     PVQSGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT          266 a          154 c          145 g          281 t
ORIGIN      
        1 ttccaacggc atgactgaga acatccacca cggttggcat cacgcatact ctagacggat
       61 tgttttgaca attctaatct tttagacttt gcataataac tgttaaacag ttgaaaatta
      121 acccagtttt aacaagtagt caaaatacca gataaaggaa aaaagtcttt aaaatcttaa
      181 aaacgcatag tatcaggtat tgaacaatct tgatattatg cgttttattg tgggaagatt
      241 tacttcattt tctcttggaa ttgagttttc tcctacttca aaactagatg atttgctatt
      301 taaaatagcg ttccttatga ttttggcaac ctggattaaa gcgagaaaaa caaaaggggc
      361 aacttaaact ttctttatat tgcttatatg ttagtagttt tagacaaaca ccacataaaa
      421 taggcttatc ctgtatcaaa gataagggat acggctcaaa agggtgattt tctaatgaat
      481 catgacaccg ataacaagca tagtactttt tacaatcata gcattgtaaa gcaataatat
      541 ccagcttgct atggtaatga atgcatcttg tttgcttatc cactaagaaa ccctgtgcct
      601 ctatcatttc cttttccttt cttaagctcg aactgtgacg ctggttccat cttccttata
      661 aagattgatg agtccttctt ttaatgcacg aaccatgtct cctgattgaa cgggttgtgg
      721 gactttaata gtcaatagtt ccattggatt tggagcgcgg tcgattttat tgcctttggc
      781 atcatgcaaa tcttcaatat aggtttcaaa atgacggaaa cctggaccat aaaactcaac
      841 ttggtt
//
LOCUS       DAVKMO010000109          794 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVKMO010000109 DAVKMO010000000
VERSION     DAVKMO010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..794
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.110"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..>794
                     /locus_tag="VW361_002016"
     CDS             <1..>794
                     /locus_tag="VW361_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEU9744981.1"
                     /translation="LQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKIL
                     HYHKQKFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNF
                     KPAGKSIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKT
                     AESVNQALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHN
                     RLIRRWLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT          275 a          144 c          161 g          214 t
ORIGIN      
        1 tttacaacaa gtgagaaaag ggctatacaa aaaggtctat tctgccgatt acgcacaaac
       61 tgtttaccaa ttcaatcgaa aacggtcggt gaaaaagtta attttaacaa aggaaatcag
      121 agagaagatc ttacactatc ataagcaaaa attttcgcct gaaatgatgg ttaacaagaa
      181 gcaagtgaaa gttggtattt caaccatcta ctactggttt cataatggtc atttaggatt
      241 gacgaaggcc gacatgcttt atcccagaaa aaggaaaggt gtcaagaagc aagctagtcc
      301 gaactttaag ccggcaggta aatctatcga agaacgtcct gacgttatta atcttcgctt
      361 ggaaaatggt cattatgaaa ttgataccgt cctactgact aagataaaaa attattgcct
      421 gttagtctta accgaccggc ggagcagaca ccaaattata aggttaattc caaataaaac
      481 tgctgaatct gtcaatcagg cgcttacgtt actattaggg gagcatcgta ttctgtccat
      541 tactgcagat aatggttcgg agttcaaacg attgtctgag gtatttcctg aggaacatat
      601 ctactacgca catgcttact cttcatggga gagaggttca aatgaaaatc ataatcgatt
      661 aattcggaga tggttaccta aaggaaccaa gaaaacgact ccgaaagaag tagcttttat
      721 cgaaaattgg attaacaact accctaaaaa atgcttggac tacaagtcgc caagtgaatt
      781 tcttttgggt ggct
//
LOCUS       DAVKMO010000110          683 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVKMO010000110 DAVKMO010000000
VERSION     DAVKMO010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..683
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.111"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..>683
                     /locus_tag="VW361_002017"
     CDS             <1..>683
                     /locus_tag="VW361_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="catalyzes the formation of UDP-glucuronate from
                     UDP-glucose; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEU9744982.1"
                     /translation="DYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFSNKL
                     KRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTHSTANI
                     KNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPRIGN
                     FYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPKI
                     VGIYKLGMK"
BASE COUNT          251 a           82 c          126 g          224 t
ORIGIN      
        1 agattatgat gagaaaattg gtagttttaa tacatatgaa atcgaacaaa cggtatcgaa
       61 gattctgagg gtaaaaccta atggaaagat tattttaaag tcaacagttc cgatcggctt
      121 ttcaaacaaa ttaaaaaggc tgtttgatac aaaaaatatc atttttgtcc ctgaattttt
      181 gagagaaggt tgttctatat atgataattt atatccaagt cgcatagttg ttggagatga
      241 gacagttgaa ggaagaaaaa ttgcagagtt gttcctttcg attagtactc atagtactgc
      301 caatattaaa aatgttatgt tagtttctcc tactgaagca gaagcaatta agcttttttc
      361 taacacattc ttagctctcc gtgttgcttt ttttaatgaa ctagattctt ttgctgagag
      421 gagaagttta aatgctgaag ttgtaataaa aggtgtttgt ttagatccaa gaattggaaa
      481 tttttataat aatccttctt ttggatttgg aggatattgt cttcccaaag atactaaaca
      541 attaaaaaaa gaatttatag aaataaatgc cccagtgata gaagcgattg atatttcaaa
      601 cacaaataga aaacagttca tagttaaaca aatattggaa cgaaagccaa agatagtagg
      661 aatatataaa ttggggatga aat
//
LOCUS       DAVKMO010000111          503 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVKMO010000111 DAVKMO010000000
VERSION     DAVKMO010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..503
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.112"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..>503
                     /locus_tag="VW361_002018"
     CDS             <1..>503
                     /locus_tag="VW361_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9744983.1"
                     /translation="GGEYQIKNLSYKFTDDECLSLKDISFKLGKIYGIIGSNGRGKST
                     LLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVMQDVNHQLFKDEVFNELRLGVKN
                     FDEEKAKIILKDLCLDEFIERHPMSLSGGQKQRLAIASVMCKNSPFVFFDEPSSGMDY
                     SNMIKIS"
BASE COUNT          193 a           61 c          101 g          148 t
ORIGIN      
        1 ggtggagagt atcagataaa aaatcttagc tacaaattta ctgatgatga gtgtttaagc
       61 ttaaaagata tttcgttcaa gcttgggaaa atttatggca taataggatc caacggacga
      121 ggaaaatcaa cgcttttaag atgtttaata ggtcttgaga aaaaatcaaa agaagaaatt
      181 tattttaagg gagagaagct atctaaaaaa gaaagactca aaaactcttc acttgttatg
      241 caagatgtaa atcatcaatt attcaaagat gaagtattca acgagcttag attaggagta
      301 aagaattttg atgaagaaaa ggcgaaaatc attttaaaag atttatgcct ggacgaattt
      361 attgaaaggc atccgatgag tttatcagga gggcaaaagc aaaggcttgc aatagcatct
      421 gttatgtgca agaattctcc atttgtcttt tttgacgaac cttcaagtgg tatggattat
      481 tccaatatga taaaaatatc tga
//
LOCUS       DAVKMO010000112          478 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVKMO010000112 DAVKMO010000000
VERSION     DAVKMO010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.113"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            27..245
                     /locus_tag="VW361_002019"
     CDS             27..245
                     /locus_tag="VW361_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9744984.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
BASE COUNT          205 a           53 c           92 g          128 t
ORIGIN      
        1 ttaatgaaga aaaaaagagg gatattatgg cacttaacta taaaccatta tggatacagt
       61 tagcaaaaaa aggactaaag aaaacagatg taatagctat ggcaggactt acaacaaatg
      121 ttatggcaca aatgggaaag gataaaccaa ttacatttaa gaatttagaa agaatatgta
      181 aggctttatc ttgcactcct aatgatatta ttagttttga agataatttt agtgacgagg
      241 aatagaaaat gactttaagg acagaagatc aagttaggga ttatgcaaga gaagtatagg
      301 ctttaatgaa gttgaagaaa acatcaatca aggtactggt caaataacta cttttaatca
      361 attaggcttc aagggatatt cagataagcc agatggttgg tatttaccta aaaatatgaa
      421 tgatgtagca ataatccttg aaacaaaatc agaagaaaga gatattagca aacaaatt
//
LOCUS       DAVKMO010000113          410 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVKMO010000113 DAVKMO010000000
VERSION     DAVKMO010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..410
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.114"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            <1..>410
                     /locus_tag="VW361_002020"
     CDS             <1..>410
                     /locus_tag="VW361_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9744985.1"
                     /translation="FGKERKSLQGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEG
                     RMKSIHYVSTVTNCYKAAVDAYLESPEKFEAIKQDLVDEMWKVAQRELATGFYYGTPS
                     ENEQLFGARRKIPEYKFVAEVVSYDDAAQTATIR"
BASE COUNT          124 a           74 c          101 g          111 t
ORIGIN      
        1 tttgggaaag aacgtaagag tttgcagggt gagattccag aagaattttc aatgtcagcc
       61 gttgacatgt ctatgattga ccacattcca gatatgattg aaaatggtgt ggacagtcta
      121 aaaatcgaag gacgtatgaa gtctattcac tacgtatcaa cagtaaccaa ctgctacaag
      181 gcggctgtgg atgcctatct tgaaagtcct gaaaagtttg aagctatcaa acaagacttg
      241 gtggacgaga tgtggaaggt tgcccaacgt gaactggcta caggatttta ctatggtaca
      301 ccatctgaaa atgagcagtt gtttggtgct cgccgtaaaa ttcctgagta caagtttgtc
      361 gctgaagtgg tttcttatga tgatgcggca caaacagcaa ccattcgtca
//
LOCUS       DAVKMO010000114          404 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVKMO010000114 DAVKMO010000000
VERSION     DAVKMO010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..404
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.denovo.115"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            1..404
                     /locus_tag="VW361_002021"
                     /pseudo
     CDS             1..404
                     /locus_tag="VW361_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          134 a           81 c           87 g          102 t
ORIGIN      
        1 gctaaagggg ttaacgtggg aatttcaacc atttactatt ggattcatca tggaaaattg
       61 gggtaaagca agcaggatct gctttaccct agaaaaggaa aagcgcttaa gaaacaggcc
      121 agcaccaact ttaaacctgc tggtcaatcc atcgaacagc ggcctgaagc tatcaatttt
      181 cgcttggaga atgggcatta tgagattgat acggttctac ttacgagagc gaaaaactac
      241 tgcttgcttg tcttgacgga tcgaaaaagt agacatcaga tcatccgatt gattccaaat
      301 aaaagtgctg aggtggtcaa tcaggctcta aaactcatct taaaacaaca caagattctt
      361 tccatcacgg cagataatgg aacggaattc aatcgcttgt ctaa
//
LOCUS       DAVKMO010000115         2139 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00030258
            SAMN33606452-rid17954033.guided.091, whole genome shotgun sequence.
ACCESSION   DAVKMO010000115 DAVKMO010000000
VERSION     DAVKMO010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606452
            Sequence Read Archive: SRR23727343
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722385.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722385.1
            Genome Coverage       :: 151x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/07/2023 02:18:58
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,025
            CDSs (total)                      :: 1,975
            Genes (coding)                    :: 1,834
            CDSs (with protein)               :: 1,834
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 72 of 141
            Pseudo Genes (incomplete)         :: 61 of 141
            Pseudo Genes (internal stop)      :: 42 of 141
            Pseudo Genes (multiple problems)  :: 29 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2139
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606452-rid17954033.guided.091"
                     /strain="AUSMDU00030258"
                     /serotype="3"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST180"
     gene            302..730
                     /locus_tag="VW361_002022"
     CDS             302..730
                     /locus_tag="VW361_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9744986.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            809..1396
                     /locus_tag="VW361_002023"
     CDS             809..1396
                     /locus_tag="VW361_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEU9744987.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYVNQEFKSYIDHM
                     LNKEAKIIGFSAGALLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELVNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            1678..1926
                     /locus_tag="VW361_002024"
     CDS             1678..1926
                     /locus_tag="VW361_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEU9744988.1"
                     /translation="MCKPISIELCDDEVHSLHEWIDGRDAIDSILAYSENQQYTYGVE
                     AGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            2031..>2139
                     /locus_tag="VW361_002025"
     CDS             2031..>2139
                     /locus_tag="VW361_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEU9744989.1"
                     /translation="MDDEASKQLSDSRFKILVGVQRTTFEEMLAVLKTAY"
BASE COUNT          791 a          290 c          437 g          621 t
ORIGIN      
        1 cacaaggaaa tcatcgccaa actggactac gacgcaccat gttgaggcag tatcactgct
       61 tgtacaagct gaggcatcag cgaagtagaa gtaaatgatc tcccatgcgg taggactcgt
      121 agaatgagga ggaaaaccga cgaaatgata aggtaagtcc gaaccgctga gtgcgtggct
      181 ctgctcttcc gatctgagac agtcgaaaag tagaagggga tggtattggt atcaatcaat
      241 gagtaacaaa gtatcagcat gattcgaaac atttacttgt aatttgcgga ggaacatcaa
      301 tatggatgga ataacaaaag attttataaa aacggctaaa ctaatgaaac aattatggcc
      361 ccaattgacc gataaagaag ctattgatga agtaaaaaaa tatacgaatg gcaaaaatac
      421 tgcaatcttt actgaagttg aaggtgacac aattgtaggt ctagcactat gttcactcag
      481 atttgattat gttgaaggtt gtaaatatag tcctgttgga ttcttagaag ggattattgt
      541 tgacgaggaa tatcgtttaa aggatattgc taaaaatctc tgtacaaaat gtgaggaatg
      601 ggcgaaaaat aaaggatgta aggaatttgc aagtgactgt actttaacga atacggattc
      661 tataagattt catctcaata ttggatttca ggaggcaaat agaattattc attttaagaa
      721 aaaattataa tttagaaacg tgaataaact tgtttaaact ttatgtatct ttagaaagtg
      781 tgttaacttg aaagaacaaa tttttttgat gggtgggaat cccccaatga agaaatatag
      841 tattgttgat aaaattgtat tatcaaccaa gattaaaaga attatcattt ttacagtttt
      901 tcgagaaaat tgggaaccgt acatgaaaaa gtacacggaa gtttttcaaa gtcaatttcc
      961 taatctaaac attgattact tgctcctgga cactgagcag attgatcttg atagctatct
     1021 agatgctgac ataattatca tcggtggtgg aaatacggaa aaatatattg ctacttatgt
     1081 taatcaggag ttcaaaagtt atatcgatca tatgcttaat aaagaggcaa aaattatagg
     1141 attttctgca ggagccctac tattaggaga aaaagtctat gtctcaccta atgataattc
     1201 agatcatcag ataaagataa aaaatggatt aggactcttt agtcagtttt taattagtgt
     1261 ccattatgat tcctggaatg ataaagcaaa taaggataga gctgaagaac tcgttaatgt
     1321 tcccataatt ccactaaatg atcattcttg tcttgtattg gataaacttg gaaacatcat
     1381 agagaaaatt gattaacttt cataatgtaa aaatggatct aggaaataaa agtgtagacg
     1441 aactggatag gttactagtg aaaactgcaa aaagtgttgt aaagtgaatc ggagtgtgct
     1501 tgatggattt tagtagtaag atagccataa ataaaggctg gtcagatgat aaaaaatatt
     1561 gtgtgacaga tcaaaatcag taaaaatatt tcttgcgtgt ttctgataag tcgaagttag
     1621 attataaaaa aatttgaatt tgatatgatg gagaaagtag cttctcttgg agttccgatg
     1681 tgtaaaccaa ttagcattga actctgcgat gacgaagtac attctttaca cgaatggata
     1741 gacggaagag atgcaataga tagcatttta gcttattcag aaaaccaaca atacacatat
     1801 ggtgtagaag caggaaagat acttagaaag attcatacaa ttcctgctac agaagtttgt
     1861 gaagattggg aaattttttt taatctaaaa attgatgata aaatctccaa cgaaatgata
     1921 tggtaagtcc gaaacgctca gtgtgtaagc ttgttgctaa aagcgtaaaa accttggaac
     1981 gaaaggaata atagacttcc tgcgaaacaa aaatacaata caataaaact atggatgatg
     2041 aagcaagtaa acaattaagc gatagccgtt tcaagatcct tgtaggtgtt cagcgcacga
     2101 cttttgaaga gatgttagct gtgttaaaaa cagcttatc
//
